Approved Project
Predicting Response in Triple Negative Breast Cancer Using Machine Learning
Keyword(s): Triple negative breast cancer, outcome prediction, digital pathology
Year: 2025
Approved Project
Characterising the Healthy Breast across Ageing and Menopause
Keyword(s): CosMx, Ageing, Menopause, Breast Cancer
Year: 2025
Approved Project
Coming unglued - elucidating the role of Norepinephrine on Transglutaminase 2 in breast cancer C
Keyword(s): Triple Negative Breast cancer, Transglutaminase 2, stress, Norepinephrine
Year: 2025
Approved Project
Targeting 11β-HSD1 to Prevent Chemotherapy Resistance in Triple Negative Breast Cancer
Keyword(s): Triple-negative breast cancer (TNBC), Tumour associated macrophage, steroid metabolism, chemotherapy
Year: 2025
Approved Project
Project Sirius - A low cost non-invasive diagnostic platform
Keyword(s): Breast cancer, exosomes, microfluidics, surface enhanced Raman scattering (SERS), machine learning
Year: 2025
Approved Project
JAKinibs as chemosensitisers in primary poor prognosis breast cancer
Keyword(s): JAK inhibitors, cancer-associated fibroblasts, chemoresistance
Year: 2025
Approved Project
JAKinibs as chemosensitisers in primary poor prognosis breast cancer
Keyword(s): chemotherapy; metastases; combination therapy; tumour microenvironment
Year: 2025
Publications
Cancer-Associated Fibroblasts Move and Interact More with Triple-Negative Breast Cancer Cells and Stimulate Their Proliferation in a Hyaluronan-Dependent Manner
Institution: Karolinska Institutet
Keyword(s): cancer-associated fibroblasts, triple-negative breast cancer, 3D spheroid co-culture models, hyaluronan
Summary: While normal fibroblasts suppress tumor growth, during cancer initiation and progression, this capacity can be lost and even switched to tumor-promoting, for reasons that are no...
Year: 2025
Publications
Clinical utility of 'Shaken' biopsies for whole-genome sequencing
Institution: Barts Cancer Institute, Queen Mary University of London
Keyword(s): whole genome sequencing, genomics, ex vivo biopsies
Summary: AIMS. Whole-genome sequencing (WGS) is beginning to be applied to cancer samples in the clinical setting. This ideally requires high-quality, minimally degraded DNA of high tumo...
Year: 2025
