Publications
Diffuse reflectance and fluorescence spectroscopy for breast conserving surgery
Institution: Department of Surgery & Cancer, Imperial College London
Keyword(s): Breast cancer margins, Intraoperative margin assessment, spectroscopy, Intrinsic fluorescence, Diffuse reflectance spectroscopy
Summary: PURPOSE. The major challenge in breast conserving surgery is the high rates of re-excision due to positive resection margins. This study evaluates whether a combined diffuse ref...
Year: 2025
Publications
Epigenetic deprogramming by disruption of CIZ1-RNA nuclear assemblies in early-stage breast cancers
Institution: University of York
Keyword(s): Breast cancer, CIZ1, X chromosome, RNA-protein complexes, Chromatin
Summary: This paper shows that protein fragments derived from the CIZ1 gene disperse nuclear CIZ1-RNA assemblies, exposing underly loci and changing gene expression. The interference mec...
Year: 2025
Publications
Hidden costs and unmet supportive care needs among individuals with experience of breast cancer and their carers in the United Kingdom
Institution: Institute of Cancer Research
Keyword(s): -
Summary: BACKGROUND. The impact of cancer transcends physical health, affecting mental wellbeing, financial stability, and ability to perform daily tasks, influencing not only patients b...
Year: 2025
Publications
Subtype-Specific Detection in Stage Ia Breast Cancer: Integrating Raman Spectroscopy, Machine Learning, and Liquid Biopsy for Personalised Diagnostics
Institution: University of Edinburgh
Keyword(s): Raman spectroscopy, machine learning, early detection, stage Ia, plasma
Summary: This study explores the integration of Raman spectroscopy (RS) with machine learning for the early detection and subtyping of breast cancer using blood plasma samples. We perfor...
Year: 2025
Publications
The clinical and molecular landscape of breast cancer in women of African and South Asian ancestry
Institution: Barts Cancer Institute, Queen Mary University of London
Keyword(s): genetic ancestry, inequality, African, South Asian, European, genomics, multi-modal
Summary: Addressing existing racial disparity in breast cancer is crucial to ensure equitable benefit across diverse communities. We evaluate the molecular and clinical effects of geneti...
Year: 2025
Approved Project
AI gBRCA digital pathology tool: A non-interventional multi-centric performance study with local evidence generation
Keyword(s): BRCA, germline testing, AI, digital pathology
Year: 2024
Approved Project
Mini replicas of human breast in the lab for patient-specific cancer research
Keyword(s): organoids, hydrogels, 3D culture
Year: 2024
Approved Project
A blood test to distinguish benign from cancerous masses
Keyword(s): A blood test to distinguish benign from cancerous masses
Year: 2024
Approved Project
Uncovering the role of the oestrogen receptor in early breast cancer transformation
Keyword(s): Estrogen Receptor, Breast Cancer, Epigenetics, Transformation
Year: 2024
