Approved Project
Investigating expression of proteins associated with breast cancer metastasis and progression
Keyword(s): ER+ breast cancer, bone metastasis, protein expression, cancer progression
Year: 2024
Approved Project
COMRADE: Combined Antibody-Drug Conjugates and Radiotherapy for Triple Negative Breast Cancer
Keyword(s): antibody-drug conjugates, PARP inhibitors, radiotherapy
Year: 2024
Approved Project
Establishing the UK-Qatar Precision Healthcare collaborative (2nd application)
Keyword(s): IDC, DCIS, British, Qatari, tumour, adjacent, Nanostring
Year: 2024
Approved Project
Blood biomarkers of brain metastasis/metastasis risk in early breast cancer
Keyword(s): Metastatic risk, inflammatory proteins, blood biomarker
Year: 2024
Approved Project
The development of in vitro patient derived cell lines for anticancer lead optimisation
Keyword(s): patient-derived cell lines, targeted therapy, drug screening
Year: 2024
Approved Project
The role of breast cancer associated extracellular matrix in driving the pathogenic phenotype of macrophages and other myeloid cells
Keyword(s): extracellular matrix, macrophages, hypoxia
Year: 2024
Approved Project
Creation and Profiling of Patient-Derived Breast Lactiferous Duct in a Comprehensive Microenvironment
Keyword(s): microfluidics, lactiferous duct, organ-on-chip
Year: 2024
Publications
A gap analysis of UK biobank publications reveals SNPs associated with intrinsic subtypes of breast cancer
Institution: Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde
Keyword(s): biobanks, UK Biobank, meta-analysis, subtype analysis,
Summary: Breast cancer is a multifaceted disease and a leading cause of cancer morbidity and mortality in females across the globe. In 2020 alone, 2.3 million women were diagnosed and 68...
Year: 2024
Publications
A novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis
Institution: York Biomedical Research Institute, University of York
Keyword(s): cancer microenvironment
Summary: Solid tumours have abnormally high intracellular [Na+]. The activity of various Na+ channels may underlie this Na+ accumulation. Voltage-gated Na+ channels (VGSCs) have been sho...
Year: 2024
