The ITIM-containing receptor: Leukocyte-Associated Immunoglobulin-Like Receptor-1 (LAIR-1) modulates immune response and confers poor prognosis in invasive breast carcinoma

Institution: School of Medicine, University of Nottingham

Corresponding Researcher: Emad Rakha

Email: emad.rakha@nottingham.ac.uk

Publication Link(s): https://doi.org/10.3390/cancers13010080

Data Link(s): 3rd Party Data: Restrictions apply to the availability of these data.

Keyword(s): LAIR-1, collagens, immune cell markers, prognosis

Summary

The leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) plays a role in immune response homeostasis, extracellular matrix remodelling and it is overexpressed in many high-grade cancers. This study aimed to elucidate the biological and prognostic role of LAIR-1 in invasive breast cancer (BC).