Research Catalogue

The Research Catalogue provides a comprehensive overview of research projects approved to use Breast Cancer Now Biobank specimens and the outputs generated from this work. Here, researchers can explore approved and ongoing projects, access associated publications and resources, and learn how Biobank-supported research is advancing breast cancer research.

136 to 144 of 344 results found
Publications Rare germline copy number variants (CNVs) and breast cancer risk
Institution: Department of Public Health and Primary Care, University of Cambridge
Keyword(s): germline, BRCA1, copy number variants, genome-wide association studies, European ancestry
Summary: Germline copy number variants (CNVs) are pervasive in the human genome but potential disease associations with rare CNVs have not been comprehensively assessed in large datasets...
Year: 2022
Publications Reciprocal Interactions Between the Gut Microbiome and Mammary Tissue Mast Cells Promote Metastatic Dissemination of HR+ Breast Tumors
Institution: Department of Microbiology Immunology and Cancer Biology, University of Virginia
Keyword(s): IHC, tumor-adjacent, dysbiosis, hormone-receptor positive
Summary: Establishing commensal dysbiosis, defined as an inflammatory gut microbiome with low biodiversity, prior to breast tumor initiation, enhances early dissemination of hormone rece...
Year: 2022
Publications The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples
Institution: European Translational Oncology Prevention and Screening (EUTOPS) Institute, Universität Innsbruck; Department of Women's Cancer, University College London
Keyword(s): ovarian cancer, translational research, epigenetics, methylation, BRCA mutations
Summary: Genetic and non-genetic factors contribute to breast cancer development. An epigenome-based signature capturing these components in easily accessible samples could identify wome...
Year: 2022
Publications Volumetric high-resolution X-ray phase-contrast virtual histology of breast specimens with a compact laboratory system
Institution: Department of Medical Physics and Biomedical Engineering, University College London
Keyword(s): breast conserving surgery, multi-resolution imaging, X-ray phase contrast
Summary: The assessment of margin involvement is a fundamental task in breast conserving surgery to prevent recurrences and reoperations. It is usually performed through histology, which...
Year: 2022
Publications Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment
Institution: Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
Keyword(s): common germline genetic variants, breast cancer-specific survival, patient subgroups, tumor biology, systemic treatment
Summary: BACKGROUND. Given the high heterogeneity among breast tumors, associations between common germline genetic variants and survival that may exist within specific subgroups could g...
Year: 2021