Research Catalogue

The Research Catalogue provides a comprehensive overview of research projects approved to use Breast Cancer Now Biobank specimens and the outputs generated from this work. Here, researchers can explore approved and ongoing projects, access associated publications and resources, and learn how Biobank-supported research is advancing breast cancer research.

181 to 189 of 344 results found
Publications Integrated analysis of key differentially expressed genes identifies DBN1 as a predictive marker of response to endocrine therapy in luminal breast cancer
Institution: University of Nottingham Biodiscovery Institute
Keyword(s): DBN1, oestrogen receptor, endocrine resistance, predictive biomarker
Summary: Endocrine therapy is the mainstay of adjuvant treatment for patients with luminal breast cancer. Despite ongoing advances in endocrine therapy to date, a proportion of patients...
Year: 2020
Publications PIK3Cδ expression by fibroblasts promotes triple-negative breast cancer progression
Institution: School of Life Sciences, University of Sussex
Keyword(s): triple negative breast cancer, cell biology, protein kinases, signal transduction, fibroblasts, PIK3Cδ
Summary: As there is growing evidence for the tumor microenvironment's role in tumorigenesis, we investigated the role of fibroblast-expressed kinases in triple-negative breast cancer (T...
Year: 2020
Publications Subcellular mRNA localization regulates ribosome biogenesis in migrating cells
Institution: Barts Cancer Institute, Queen Mary University of London
Keyword(s): IHC, RNA localization, ribosome biogenesis, La-related proteins, EMT, LARP6
Summary: Translation of ribosomal protein-coding mRNAs (RP-mRNAs) constitutes a key step in ribosome biogenesis, but the mechanisms that modulate RP-mRNA translation in coordination with...
Year: 2020