Select features to define your cohort
| Patient ID | Age at Diagnosis | Sex | Race | Definition | Menopausal Status | Cancer Type | ER | PR | HER2 | Event | Event Site | Survival Status | Survival Time (years) | Subtype | Genetic Ancestry | hidden |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCGA-A7-A13G | 79 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | new primary | skin | alive | 1.97 | LumA | European | TCGA.A7.A13G.01A.11R.A13Q.07 |
| TCGA-A7-A13G | 79 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | new primary | skin | alive | 1.97 | LumA | European | TCGA.A7.A13G.11A.51R.A13Q.07 |
| TCGA-E2-A10B | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | new primary | lung | alive | 2.05 | LumA | European | TCGA.E2.A10B.01A.11R.A10J.07 |
| TCGA-E2-A14R | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | new primary | endometrial | alive | 2.31 | Basal | European | TCGA.E2.A14R.01A.11R.A115.07 |
| TCGA-A7-A13H | 61 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | new primary | skin | alive | 2.46 | NA | European | TCGA.A7.A13H.01A.11R.A22K.07 |
| TCGA-AR-A5QM | 62 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | new primary | melanoma | alive | 6.11 | LumA | European | TCGA.AR.A5QM.01A.11R.A27Q.07 |
| TCGA-B6-A2IU | 62 | female | White | Primary solid Tumor | indeterminate | ILC | positive | positive | not evaluated | new primary | lung | alive | 14.17 | LumA | European | TCGA.B6.A2IU.01A.32R.A18M.07 |
| TCGA-B6-A0WZ | 50 | female | Black or African American | Primary solid Tumor | indeterminate | IDC | positive | positive | not evaluated | new primary | bone | alive | 17.23 | LumA | African_admix | TCGA.B6.A0WZ.01A.11R.A109.07 |
| TCGA-BH-A18V | 48 | female | White | Primary solid Tumor | not available | IDC | negative | negative | negative | metastasis | intramammary node | dead | 4.26 | Basal | European | TCGA.BH.A18V.01A.11R.A12D.07 |
| TCGA-BH-A18V | 48 | female | White | Solid Tissue Normal | not available | IDC | negative | negative | negative | metastasis | intramammary node | dead | 4.26 | Basal | European | TCGA.BH.A18V.11A.52R.A12D.07 |
| TCGA-E9-A1NI | 51 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | positive | positive | negative | NA | NA | alive | NA | NA | European | TCGA.E9.A1NI.01A.11R.A14D.07 |
| TCGA-PL-A8LV | 54 | female | Black or African American | Primary solid Tumor | unknown | medullary carcinoma | not evaluated | not evaluated | not evaluated | NA | NA | alive | NA | Basal | African | TCGA.PL.A8LV.01A.21R.A41B.07 |
| TCGA-A2-A25D | 90 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | negative | NA | NA | alive | NA | LumA | European | TCGA.A2.A25D.01A.12R.A16F.07 |
| TCGA-A8-A06N | 66 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | NA | LumB | European | TCGA.A8.A06N.01A.11R.A00Z.07 |
| TCGA-A8-A081 | 80 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | NA | LumB | European | TCGA.A8.A081.01A.11R.A00Z.07 |
| TCGA-A8-A083 | 67 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | NA | LumA | European | TCGA.A8.A083.01A.21R.A00Z.07 |
| TCGA-A8-A08H | 66 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | NA | Normal | European | TCGA.A8.A08H.01A.21R.A00Z.07 |
| TCGA-A8-A090 | 74 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | NA | LumA | European | TCGA.A8.A090.01A.11R.A00Z.07 |
| TCGA-A8-A094 | 75 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | NA | Her2 | European | TCGA.A8.A094.01A.11R.A00Z.07 |
| TCGA-A8-A096 | 73 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | NA | LumB | European | TCGA.A8.A096.01A.11R.A00Z.07 |
| TCGA-A8-A09G | 79 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | NA | NA | alive | NA | Her2 | European | TCGA.A8.A09G.01A.21R.A00Z.07 |
| TCGA-A8-A09Z | 83 | female | not available | Primary solid Tumor | postmenopausal | ILC | positive | negative | negative | NA | NA | alive | NA | LumB | European | TCGA.A8.A09Z.01A.11R.A00Z.07 |
| TCGA-AC-A3W6 | 90 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | NA | NA | European | TCGA.AC.A3W6.01A.12R.A22K.07 |
| TCGA-C8-A12K | 80 | female | Asian | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | NA | Basal | East Asian | TCGA.C8.A12K.01A.21R.A115.07 |
| TCGA-C8-A12T | 43 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | NA | Her2 | East Asian | TCGA.C8.A12T.01A.11R.A115.07 |
| TCGA-C8-A133 | 65 | female | White | Primary solid Tumor | postmenopausal | ductal/mucinous | positive | positive | not evaluated | NA | NA | alive | NA | NA | South Asian_admix | TCGA.C8.A133.01A.32R.A12D.07 |
| TCGA-C8-A26Y | 90 | female | Asian | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | NA | Her2 | East Asian | TCGA.C8.A26Y.01A.11R.A16F.07 |
| TCGA-D8-A1JK | 90 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | positive | negative | NA | NA | alive | NA | Basal | European | TCGA.D8.A1JK.01A.11R.A13Q.07 |
| TCGA-LL-A6FP | 90 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | NA | LumA | European | TCGA.LL.A6FP.01A.11R.A31O.07 |
| TCGA-AC-A7VC | 56 | female | White | Primary solid Tumor | postmenopausal | metaplastic carcinoma | negative | negative | negative | NA | NA | alive | NA | Basal | European | TCGA.AC.A7VC.01A.11R.A352.07 |
| TCGA-C8-A275 | 56 | female | Asian | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | NA | Her2 | East Asian | TCGA.C8.A275.01A.21R.A16F.07 |
| TCGA-AN-A0AM | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.01 | LumB | European | TCGA.AN.A0AM.01A.11R.A034.07 |
| TCGA-C8-A1HJ | 53 | female | Asian | Primary solid Tumor | perimenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.01 | Basal | East Asian | TCGA.C8.A1HJ.01A.11R.A13Q.07 |
| TCGA-E9-A1N4 | 41 | female | White | Primary solid Tumor | premenopausal | IDC/ILC | positive | positive | positive | NA | NA | alive | 0.01 | NA | European | TCGA.E9.A1N4.01A.11R.A14M.07 |
| TCGA-E9-A1N4 | 41 | female | White | Solid Tissue Normal | premenopausal | IDC/ILC | positive | positive | positive | NA | NA | alive | 0.01 | NA | European | TCGA.E9.A1N4.11A.33R.A14M.07 |
| TCGA-PL-A8LX | 35 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | not evaluated | not evaluated | not evaluated | metastasis | bone|liver | alive | 0.01 | LumA | African | TCGA.PL.A8LX.01A.11R.A41B.07 |
| TCGA-C8-A273 | 29 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.02 | LumA | East Asian | TCGA.C8.A273.01A.11R.A16F.07 |
| TCGA-AN-A041 | 29 | female | White | Primary solid Tumor | premenopausal | IDC | positive | negative | positive | NA | NA | alive | 0.02 | LumA | European_admix | TCGA.AN.A041.01A.11R.A034.07 |
| TCGA-C8-A12W | 49 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.02 | LumB | East Asian | TCGA.C8.A12W.01A.11R.A115.07 |
| TCGA-C8-A138 | 54 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | negative | equivocal | NA | NA | alive | 0.02 | Her2 | East Asian | TCGA.C8.A138.01A.11R.A115.07 |
| TCGA-C8-A1HK | 53 | female | Asian | Primary solid Tumor | perimenopausal | IDC | negative | negative | positive | NA | NA | alive | 0.02 | Her2 | East Asian | TCGA.C8.A1HK.01A.21R.A13Q.07 |
| TCGA-C8-A26W | 58 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.02 | LumB | East Asian | TCGA.C8.A26W.01A.11R.A16F.07 |
| TCGA-C8-A3M8 | 68 | female | Asian | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 0.02 | LumB | East Asian | TCGA.C8.A3M8.01A.11R.A213.07 |
| TCGA-AR-A0U0 | 73 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | not evaluated | NA | NA | alive | 0.02 | Basal | European | TCGA.AR.A0U0.01A.11R.A109.07 |
| TCGA-C8-A8HP | 59 | female | Asian | Primary solid Tumor | postmenopausal | metaplastic carcinoma | negative | negative | positive | NA | NA | alive | 0.02 | Her2 | East Asian | TCGA.C8.A8HP.01A.11R.A36F.07 |
| TCGA-E9-A5FL | 65 | female | White | Primary solid Tumor | postmenopausal | metaplastic carcinoma | negative | negative | negative | NA | NA | alive | 0.02 | Basal | European | TCGA.E9.A5FL.01A.11R.A27Q.07 |
| TCGA-PL-A8LY | 30 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.02 | Normal | African | TCGA.PL.A8LY.01A.11R.A41B.07 |
| TCGA-AC-A5XU | 74 | female | Black or African American | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | alive | 0.02 | LumA | African | TCGA.AC.A5XU.01A.11R.A28M.07 |
| TCGA-AN-A0XP | 69 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.02 | LumA | European | TCGA.AN.A0XP.01A.11R.A109.07 |
| TCGA-C8-A26V | 47 | female | Asian | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.02 | LumB | East Asian | TCGA.C8.A26V.01A.11R.A16F.07 |
| TCGA-C8-A278 | 61 | female | Asian | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 0.02 | Her2 | East Asian | TCGA.C8.A278.01A.11R.A169.07 |
| TCGA-C8-A8HQ | 53 | female | Asian | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | negative | NA | NA | alive | 0.02 | NA | East Asian | TCGA.C8.A8HQ.01A.11R.A36F.07 |
| TCGA-AN-A03X | 74 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.03 | LumA | European | TCGA.AN.A03X.01A.21R.A00Z.07 |
| TCGA-AN-A03Y | 66 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.03 | LumB | European | TCGA.AN.A03Y.01A.21R.A00Z.07 |
| TCGA-AN-A046 | 68 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.03 | LumA | European | TCGA.AN.A046.01A.21R.A034.07 |
| TCGA-AN-A0AR | 55 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.03 | Basal | European | TCGA.AN.A0AR.01A.11R.A00Z.07 |
| TCGA-AN-A0AS | 70 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.03 | LumA | European | TCGA.AN.A0AS.01A.11R.A00Z.07 |
| TCGA-AN-A0AT | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.03 | Basal | European | TCGA.AN.A0AT.01A.11R.A034.07 |
| TCGA-AN-A0FV | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 0.03 | Her2 | European | TCGA.AN.A0FV.01A.11R.A00Z.07 |
| TCGA-AN-A0FX | 52 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 0.03 | Basal | European | TCGA.AN.A0FX.01A.11R.A034.07 |
| TCGA-AN-A0FY | 55 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.03 | LumB | European | TCGA.AN.A0FY.01A.11R.A034.07 |
| TCGA-AN-A0FZ | 45 | female | White | Primary solid Tumor | premenopausal | IDC | positive | negative | positive | NA | NA | alive | 0.03 | LumA | European | TCGA.AN.A0FZ.01A.11R.A034.07 |
| TCGA-AN-A0XN | 68 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | positive | negative | NA | NA | alive | 0.03 | LumA | European | TCGA.AN.A0XN.01A.21R.A109.07 |
| TCGA-AN-A0XR | 55 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.03 | LumB | European | TCGA.AN.A0XR.01A.11R.A109.07 |
| TCGA-AN-A0XS | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | positive | negative | NA | NA | alive | 0.03 | LumA | European | TCGA.AN.A0XS.01A.22R.A109.07 |
| TCGA-AN-A0XT | 54 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.03 | LumA | European | TCGA.AN.A0XT.01A.11R.A109.07 |
| TCGA-AN-A0XU | 54 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.03 | Basal | European | TCGA.AN.A0XU.01A.11R.A109.07 |
| TCGA-AN-A0FW | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | Indeterminate | negative | NA | NA | alive | 0.03 | LumA | European | TCGA.AN.A0FW.01A.11R.A034.07 |
| TCGA-E2-A1IL | 78 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 0.04 | LumA | European | TCGA.E2.A1IL.01A.11R.A14D.07 |
| TCGA-AN-A0G0 | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.04 | NA | European | TCGA.AN.A0G0.01A.11R.A034.07 |
| TCGA-AN-A049 | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.05 | LumA | European | TCGA.AN.A049.01A.21R.A00Z.07 |
| TCGA-E9-A1R2 | 51 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | equivocal | NA | NA | alive | 0.05 | LumA | European | TCGA.E9.A1R2.01A.11R.A14D.07 |
| TCGA-E9-A1RD | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.05 | LumA | European | TCGA.E9.A1RD.01A.11R.A157.07 |
| TCGA-E9-A1RD | 67 | female | White | Solid Tissue Normal | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.05 | LumA | European | TCGA.E9.A1RD.11A.33R.A157.07 |
| TCGA-E9-A244 | 54 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.06 | Basal | European | TCGA.E9.A244.01A.11R.A169.07 |
| TCGA-E9-A227 | 42 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.07 | LumA | European | TCGA.E9.A227.01A.11R.A157.07 |
| TCGA-D8-A27R | 41 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.08 | LumB | European | TCGA.D8.A27R.01A.11R.A16F.07 |
| TCGA-E9-A1R4 | 66 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.08 | LumB | European | TCGA.E9.A1R4.01A.21R.A14D.07 |
| TCGA-E9-A249 | 45 | female | White | Primary solid Tumor | premenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.08 | LumB | European | TCGA.E9.A249.01A.11R.A169.07 |
| TCGA-A8-A08A | 89 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.08 | LumA | European | TCGA.A8.A08A.01A.11R.A32Y.07 |
| TCGA-A8-A09W | 70 | female | not available | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 0.08 | LumB | European | TCGA.A8.A09W.01A.11R.A00Z.07 |
| TCGA-A8-A0A7 | 57 | female | not available | Primary solid Tumor | postmenopausal | ILC | negative | negative | positive | NA | NA | alive | 0.08 | Her2 | European | TCGA.A8.A0A7.01A.11R.A00Z.07 |
| TCGA-A8-A06Q | 63 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.08 | LumB | European | TCGA.A8.A06Q.01A.11R.A034.07 |
| TCGA-A8-A06Z | 84 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.08 | LumB | European | TCGA.A8.A06Z.01A.11R.A00Z.07 |
| TCGA-A8-A09C | 69 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.08 | LumB | European | TCGA.A8.A09C.01A.11R.A00Z.07 |
| TCGA-A8-A09N | 57 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.08 | LumB | European | TCGA.A8.A09N.01A.11R.A00Z.07 |
| TCGA-AC-A2QH | 58 | female | White | Primary solid Tumor | postmenopausal | metaplastic carcinoma | negative | negative | negative | NA | NA | alive | 0.08 | Basal | European | TCGA.AC.A2QH.01A.11R.A18M.07 |
| TCGA-AC-A8OQ | 72 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | Indeterminate | NA | NA | alive | 0.09 | Basal | African_admix | TCGA.AC.A8OQ.01A.11R.A41B.07 |
| TCGA-E2-A15K | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.09 | LumB | European | TCGA.E2.A15K.01A.11R.A12P.07 |
| TCGA-E2-A15K | 58 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.09 | LumB | European | TCGA.E2.A15K.11A.13R.A12P.07 |
| TCGA-E9-A1RF | 68 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.1 | LumA | European | TCGA.E9.A1RF.01A.11R.A157.07 |
| TCGA-E9-A1RF | 68 | female | White | Solid Tissue Normal | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.1 | LumA | European | TCGA.E9.A1RF.11A.32R.A157.07 |
| TCGA-AC-A8OR | 75 | female | White | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | negative | NA | NA | alive | 0.11 | NA | European | TCGA.AC.A8OR.01A.21R.A41B.07 |
| TCGA-E2-A15H | 38 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.11 | LumA | European | TCGA.E2.A15H.01A.11R.A12D.07 |
| TCGA-E9-A1R5 | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.11 | LumA | European | TCGA.E9.A1R5.01A.11R.A14M.07 |
| TCGA-E9-A243 | 52 | female | White | Primary solid Tumor | perimenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.12 | Basal | European | TCGA.E9.A243.01A.21R.A169.07 |
| TCGA-AC-A2FB | 65 | female | White | Primary solid Tumor | not available | ILC | positive | positive | positive | NA | NA | alive | 0.12 | LumA | European | TCGA.AC.A2FB.01A.11R.A17B.07 |
| TCGA-AC-A2FB | 65 | female | White | Solid Tissue Normal | not available | ILC | positive | positive | positive | NA | NA | alive | 0.12 | LumA | European | TCGA.AC.A2FB.11A.13R.A17B.07 |
| TCGA-E9-A1RI | 43 | female | White | Primary solid Tumor | premenopausal | IDC/ILC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.13 | NA | European | TCGA.E9.A1RI.01A.11R.A169.07 |
| TCGA-E9-A1RI | 43 | female | White | Solid Tissue Normal | premenopausal | IDC/ILC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.13 | NA | European | TCGA.E9.A1RI.11A.41R.A169.07 |
| TCGA-D8-A145 | 80 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.13 | LumA | European | TCGA.D8.A145.01A.11R.A115.07 |
| TCGA-D8-A27P | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.13 | LumA | European | TCGA.D8.A27P.01A.11R.A16F.07 |
| TCGA-D8-A1XS | 48 | male | White | Primary solid Tumor | not applicable | ductal/micropapillary | positive | positive | positive | NA | NA | alive | 0.14 | NA | European | TCGA.D8.A1XS.01A.11R.A14M.07 |
| TCGA-AC-A6NO | 43 | female | Black or African American | Primary solid Tumor | unknown | IDC | positive | positive | negative | NA | NA | alive | 0.14 | LumA | African_admix | TCGA.AC.A6NO.01A.12R.A33J.07 |
| TCGA-AN-A04D | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.14 | Basal | European | TCGA.AN.A04D.01A.21R.A034.07 |
| TCGA-A7-A3RF | 79 | female | White | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | negative | metastasis | bone>liver | alive | 0.15 | NA | European | TCGA.A7.A3RF.01A.11R.A22K.07 |
| TCGA-AN-A04C | 51 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 0.15 | Her2 | European | TCGA.AN.A04C.01A.21R.A034.07 |
| TCGA-AC-A3W5 | 65 | female | Black or African American | Primary solid Tumor | not evaluated | ILC | positive | positive | not evaluated | NA | NA | alive | 0.15 | Her2 | African | TCGA.AC.A3W5.01A.11R.A22K.07 |
| TCGA-AC-A62Y | 79 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 0.15 | LumA | European | TCGA.AC.A62Y.01A.11R.A29R.07 |
| TCGA-C8-A132 | 56 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 0.16 | LumA | East Asian | TCGA.C8.A132.01A.31R.A115.07 |
| TCGA-OL-A66P | 75 | female | Black or African American | Primary solid Tumor | not available | IDC | negative | negative | not evaluated | NA | NA | alive | 0.16 | Her2 | African | TCGA.OL.A66P.01A.11R.A31O.07 |
| TCGA-E9-A248 | 51 | female | White | Primary solid Tumor | perimenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.16 | Her2 | European | TCGA.E9.A248.01A.11R.A169.07 |
| TCGA-BH-A18G | 81 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.17 | Basal | European | TCGA.BH.A18G.01A.11R.A12D.07 |
| TCGA-D8-A142 | 74 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 0.17 | Basal | European | TCGA.D8.A142.01A.11R.A115.07 |
| TCGA-AC-A5EH | 76 | female | Black or African American | Primary solid Tumor | not available | IDC | positive | negative | negative | NA | NA | alive | 0.17 | Her2 | African_admix | TCGA.AC.A5EH.01A.11R.A28M.07 |
| TCGA-E9-A1R3 | 70 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.18 | LumA | European | TCGA.E9.A1R3.01A.31R.A14M.07 |
| TCGA-OK-A5Q2 | 59 | female | not available | Primary solid Tumor | unknown | ILC | positive | positive | negative | NA | NA | alive | 0.18 | LumA | African | TCGA.OK.A5Q2.01A.11R.A27Q.07 |
| TCGA-A7-A26J | 49 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.19 | LumA | European | TCGA.A7.A26J.01A.11R.A169.07 |
| TCGA-C8-A131 | 82 | female | Asian | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.19 | Basal | East Asian | TCGA.C8.A131.01A.11R.A115.07 |
| TCGA-AC-A8OS | 71 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 0.19 | LumA | European | TCGA.AC.A8OS.01A.12R.A41B.07 |
| TCGA-C8-A1HM | 74 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.19 | LumB | East Asian | TCGA.C8.A1HM.01A.12R.A137.07 |
| TCGA-AC-A23E | 50 | female | White | Primary solid Tumor | not available | IDC | positive | positive | not evaluated | NA | NA | alive | 0.2 | LumA | European | TCGA.AC.A23E.01A.11R.A157.07 |
| TCGA-BH-A0HL | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.2 | NA | European | TCGA.BH.A0HL.01A.11R.A10U.07 |
| TCGA-D8-A1Y2 | 71 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | Indeterminate | NA | NA | alive | 0.2 | LumB | European | TCGA.D8.A1Y2.01A.11R.A157.07 |
| TCGA-D8-A27V | 62 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 0.2 | LumA | European | TCGA.D8.A27V.01A.12R.A17B.07 |
| TCGA-AC-A7VB | 51 | female | Black or African American | Primary solid Tumor | unknown | IDC | positive | negative | not evaluated | NA | NA | alive | 0.2 | LumB | African_admix | TCGA.AC.A7VB.01A.11R.A352.07 |
| TCGA-A7-A3J1 | 63 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 0.21 | NA | European | TCGA.A7.A3J1.01A.11R.A213.07 |
| TCGA-D8-A1XG | 86 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.21 | LumA | European | TCGA.D8.A1XG.01A.11R.A14D.07 |
| TCGA-A7-A3J0 | 62 | female | White | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | negative | NA | NA | alive | 0.21 | NA | European | TCGA.A7.A3J0.01A.11R.A213.07 |
| TCGA-BH-A0HO | 48 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.21 | LumA | European | TCGA.BH.A0HO.01A.11R.A034.07 |
| TCGA-AQ-A54N | 51 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 0.21 | NA | African | TCGA.AQ.A54N.01A.11R.A266.07 |
| TCGA-BH-A0DS | 71 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.21 | LumA | European | TCGA.BH.A0DS.01A.11R.A056.07 |
| TCGA-HN-A2NL | 56 | female | not available | Primary solid Tumor | postmenopausal | ILC | negative | negative | negative | NA | NA | alive | 0.22 | Basal | European | TCGA.HN.A2NL.01A.11R.A18M.07 |
| TCGA-LL-A6FQ | 77 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.22 | LumA | African | TCGA.LL.A6FQ.01A.11R.A31O.07 |
| TCGA-D8-A1XY | 74 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.22 | LumA | European | TCGA.D8.A1XY.01A.11R.A14M.07 |
| TCGA-AR-A24P | 47 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.23 | LumA | European | TCGA.AR.A24P.01A.11R.A169.07 |
| TCGA-E9-A1R6 | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.23 | LumA | European | TCGA.E9.A1R6.01A.11R.A14D.07 |
| TCGA-D8-A1X7 | 40 | female | White | Primary solid Tumor | premenopausal | ductal partially papillary | positive | positive | negative | NA | NA | alive | 0.23 | NA | European | TCGA.D8.A1X7.01A.11R.A14M.07 |
| TCGA-MS-A51U | 44 | female | White | Primary solid Tumor | not available | ILC | positive | positive | negative | NA | NA | alive | 0.23 | NA | European | TCGA.MS.A51U.01A.31R.A266.07 |
| TCGA-AN-A04A | 36 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.25 | LumA | European | TCGA.AN.A04A.01A.21R.A034.07 |
| TCGA-E9-A6HE | 45 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 0.25 | LumA | European | TCGA.E9.A6HE.01A.11R.A31O.07 |
| TCGA-AC-A3TM | 50 | female | White | Primary solid Tumor | perimenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 0.25 | NA | European | TCGA.AC.A3TM.01A.11R.A22K.07 |
| TCGA-C8-A130 | 52 | female | Asian | Primary solid Tumor | perimenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.26 | LumB | East Asian | TCGA.C8.A130.01A.31R.A115.07 |
| TCGA-D8-A1JF | 79 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.26 | Her2 | European | TCGA.D8.A1JF.01A.11R.A13Q.07 |
| TCGA-D8-A1XF | 45 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.27 | LumB | European | TCGA.D8.A1XF.01A.11R.A14D.07 |
| TCGA-LL-A5YO | 50 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.27 | Her2 | African | TCGA.LL.A5YO.01A.21R.A28M.07 |
| TCGA-BH-A0DQ | 42 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.27 | LumA | European | TCGA.BH.A0DQ.01A.11R.A084.07 |
| TCGA-BH-A0DQ | 42 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.27 | LumA | European | TCGA.BH.A0DQ.11A.12R.A089.07 |
| TCGA-BH-A5IZ | 51 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.27 | Basal | African | TCGA.BH.A5IZ.01A.11R.A27Q.07 |
| TCGA-LL-A7T0 | 70 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.27 | LumB | African | TCGA.LL.A7T0.01A.31R.A352.07 |
| TCGA-C8-A1HN | 56 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.27 | LumB | East Asian | TCGA.C8.A1HN.01A.11R.A137.07 |
| TCGA-LL-A5YP | 49 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.27 | Basal | African | TCGA.LL.A5YP.01A.21R.A28M.07 |
| TCGA-BH-A0E0 | 38 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.37 | Basal | European | TCGA.BH.A0E0.01A.11R.A056.07 |
| TCGA-BH-A0E0 | 38 | female | White | Solid Tissue Normal | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.37 | Basal | European | TCGA.BH.A0E0.11A.13R.A089.07 |
| TCGA-BH-A6R9 | 61 | female | White | Primary solid Tumor | postmenopausal | metaplastic carcinoma | negative | positive | negative | NA | NA | alive | 0.44 | Normal | European | TCGA.BH.A6R9.01A.21R.A32P.07 |
| TCGA-AN-A0XV | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.44 | LumA | European | TCGA.AN.A0XV.01A.11R.A109.07 |
| TCGA-AN-A0XL | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.45 | LumA | European | TCGA.AN.A0XL.01A.11R.A10J.07 |
| TCGA-E2-A2P6 | 77 | female | not available | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | NA | NA | alive | 0.46 | LumA | American | TCGA.E2.A2P6.01A.11R.A19W.07 |
| TCGA-AN-A0XW | 36 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.47 | LumA | European | TCGA.AN.A0XW.01A.11R.A109.07 |
| TCGA-BH-A0RX | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.47 | Basal | European | TCGA.BH.A0RX.01A.21R.A084.07 |
| TCGA-AN-A0FF | 32 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.47 | LumB | European | TCGA.AN.A0FF.01A.11R.A034.07 |
| TCGA-BH-A0HK | 81 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.49 | LumA | European | TCGA.BH.A0HK.01A.11R.A056.07 |
| TCGA-BH-A0HK | 81 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.49 | LumA | European | TCGA.BH.A0HK.11A.11R.A089.07 |
| TCGA-EW-A1PC | 66 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.51 | NA | African | TCGA.EW.A1PC.01B.11R.A21T.07 |
| TCGA-AN-A0FD | 71 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.54 | LumA | European | TCGA.AN.A0FD.01A.11R.A034.07 |
| TCGA-BH-A28Q | 46 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 0.54 | LumA | European | TCGA.BH.A28Q.01A.11R.A16F.07 |
| TCGA-AN-A0FS | 55 | female | White | Primary solid Tumor | perimenopausal | ILC | positive | negative | positive | NA | NA | alive | 0.57 | LumA | European | TCGA.AN.A0FS.01A.11R.A034.07 |
| TCGA-AN-A0FK | 88 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.58 | LumA | European | TCGA.AN.A0FK.01A.11R.A034.07 |
| TCGA-AN-A0FT | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.59 | LumA | European | TCGA.AN.A0FT.01A.11R.A034.07 |
| TCGA-B6-A400 | 43 | female | Black or African American | Primary solid Tumor | unknown | IDC | negative | negative | negative | NA | NA | alive | 0.59 | NA | African | TCGA.B6.A400.01A.11R.A239.07 |
| TCGA-LD-A7W5 | 52 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.59 | LumA | African | TCGA.LD.A7W5.01A.22R.A352.07 |
| TCGA-AN-A0FN | 61 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 0.6 | LumA | European | TCGA.AN.A0FN.01A.11R.A034.07 |
| TCGA-BH-A18I | 53 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.6 | LumA | European | TCGA.BH.A18I.01A.11R.A12D.07 |
| TCGA-A2-A4RW | 49 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 0.61 | NA | European | TCGA.A2.A4RW.01A.21R.A266.07 |
| TCGA-AN-A0AK | 76 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | NA | NA | alive | 0.61 | LumB | European | TCGA.AN.A0AK.01A.21R.A00Z.07 |
| TCGA-AR-A2LL | 70 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 0.61 | NA | European | TCGA.AR.A2LL.01A.11R.A180.07 |
| TCGA-GI-A2C8 | 63 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | alive | 0.62 | LumA | European | TCGA.GI.A2C8.01A.11R.A16F.07 |
| TCGA-GI-A2C8 | 63 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | negative | NA | NA | alive | 0.62 | LumA | European | TCGA.GI.A2C8.11A.22R.A16F.07 |
| TCGA-AN-A0AL | 41 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.62 | Basal | European | TCGA.AN.A0AL.01A.11R.A00Z.07 |
| TCGA-A7-A0CG | 78 | female | White | Primary solid Tumor | postmenopausal | ILC/IDC (grade 1) | positive | negative | negative | NA | NA | alive | 0.63 | NA | European | TCGA.A7.A0CG.01A.12R.A056.07 |
| TCGA-AN-A0FL | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 0.63 | Basal | European | TCGA.AN.A0FL.01A.11R.A034.07 |
| TCGA-A7-A0CH | 79 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.64 | LumA | European | TCGA.A7.A0CH.01A.21R.A00Z.07 |
| TCGA-A7-A0CH | 79 | female | White | Solid Tissue Normal | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.64 | LumA | European | TCGA.A7.A0CH.11A.32R.A089.07 |
| TCGA-A1-A0SM | 77 | male | White | Primary solid Tumor | not applicable | IDC | positive | negative | positive | NA | NA | alive | 0.66 | NA | European | TCGA.A1.A0SM.01A.11R.A084.07 |
| TCGA-AN-A0FJ | 59 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | negative | positive | NA | NA | alive | 0.66 | Basal | European | TCGA.AN.A0FJ.01A.11R.A00Z.07 |
| TCGA-E2-A56Z | 69 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.69 | LumB | African_admix | TCGA.E2.A56Z.01A.12R.A29R.07 |
| TCGA-EW-A1IY | 38 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.71 | LumB | East Asian | TCGA.EW.A1IY.01A.11R.A13Q.07 |
| TCGA-A1-A0SB | 70 | female | White | Primary solid Tumor | postmenopausal | adenoid cystic carcinoma | positive | negative | negative | NA | NA | alive | 0.71 | NA | European | TCGA.A1.A0SB.01A.11R.A144.07 |
| TCGA-A7-A6VY | 48 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.73 | Basal | African_admix | TCGA.A7.A6VY.01A.12R.A33J.07 |
| TCGA-A7-A0DB | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.73 | LumA | European | TCGA.A7.A0DB.01A.11R.A00Z.07 |
| TCGA-A7-A0DB | 56 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.73 | LumA | European | TCGA.A7.A0DB.11A.33R.A089.07 |
| TCGA-BH-A18F | 50 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.73 | LumA | European | TCGA.BH.A18F.01A.11R.A12D.07 |
| TCGA-OL-A97C | 67 | female | Black or African American | Primary solid Tumor | postmenopausal | malignant phyllodes | negative | negative | not evaluated | metastasis | lung | alive | 0.74 | NA | African | TCGA.OL.A97C.01A.32R.A41B.07 |
| TCGA-A7-A0D9 | 37 | female | White | Primary solid Tumor | premenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.75 | LumA | European | TCGA.A7.A0D9.01A.31R.A056.07 |
| TCGA-A7-A0D9 | 37 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.75 | LumA | European | TCGA.A7.A0D9.11A.53R.A089.07 |
| TCGA-A8-A07R | 80 | female | not available | Primary solid Tumor | not available | IDC | negative | negative | positive | NA | NA | alive | 0.75 | NA | European | TCGA.A8.A07R.01A.21R.A034.07 |
| TCGA-A8-A09R | 82 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.75 | LumB | European | TCGA.A8.A09R.01A.11R.A00Z.07 |
| TCGA-A8-A079 | 69 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.75 | LumB | European | TCGA.A8.A079.01A.21R.A00Z.07 |
| TCGA-A7-A6VW | 48 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.78 | Basal | African_admix | TCGA.A7.A6VW.01A.21R.A33J.07 |
| TCGA-BH-AB28 | 53 | female | White | Primary solid Tumor | unknown | ILC | positive | positive | negative | NA | NA | alive | 0.79 | LumA | European | TCGA.BH.AB28.01A.31R.A41B.07 |
| TCGA-D8-A27K | 47 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.79 | LumA | European | TCGA.D8.A27K.01A.11R.A16F.07 |
| TCGA-E9-A2JT | 63 | female | White | Primary solid Tumor | postmenopausal | ILC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.79 | LumA | European | TCGA.E9.A2JT.01A.22R.A18M.07 |
| TCGA-E2-A15O | 89 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | locoregional recurrence | not available | alive | 0.79 | LumA | African | TCGA.E2.A15O.01A.11R.A115.07 |
| TCGA-BH-A0E6 | 69 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 0.8 | Basal | European | TCGA.BH.A0E6.01A.11R.A034.07 |
| TCGA-BH-A6R8 | 46 | female | Black or African American | Primary solid Tumor | unknown | IDC | positive | positive | not evaluated | NA | NA | alive | 0.8 | LumA | African | TCGA.BH.A6R8.01A.21R.A33J.07 |
| TCGA-AO-A0J4 | 41 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.8 | Basal | African | TCGA.AO.A0J4.01A.11R.A034.07 |
| TCGA-PL-A8LZ | 29 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 0.83 | Basal | African | TCGA.PL.A8LZ.01A.31R.A36F.07 |
| TCGA-5T-A9QA | 52 | female | Black or African American | Primary solid Tumor | unknown | IDC/mucinous | positive | negative | equivocal | NA | NA | alive | 0.83 | NA | African | TCGA.5T.A9QA.01A.11R.A41B.07 |
| TCGA-AN-A0AJ | 79 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.83 | LumB | European | TCGA.AN.A0AJ.01A.11R.A00Z.07 |
| TCGA-A8-A07O | 51 | female | not available | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.83 | Basal | European | TCGA.A8.A07O.01A.11R.A00Z.07 |
| TCGA-A8-A07W | 76 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.83 | LumB | European | TCGA.A8.A07W.01A.11R.A00Z.07 |
| TCGA-A8-A099 | 76 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.83 | LumA | European | TCGA.A8.A099.01A.11R.A00Z.07 |
| TCGA-A8-A09A | 40 | female | not available | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.83 | LumA | European | TCGA.A8.A09A.01A.11R.A00Z.07 |
| TCGA-A7-A0CE | 57 | female | White | Primary solid Tumor | indeterminate | IDC | negative | negative | equivocal | NA | NA | alive | 0.85 | Basal | European | TCGA.A7.A0CE.01A.11R.A00Z.07 |
| TCGA-A7-A0CE | 57 | female | White | Solid Tissue Normal | indeterminate | IDC | negative | negative | equivocal | NA | NA | alive | 0.85 | Basal | European | TCGA.A7.A0CE.11A.21R.A089.07 |
| TCGA-A7-A6VV | 51 | female | Black or African American | Primary solid Tumor | perimenopausal | IDC | negative | negative | negative | NA | NA | alive | 0.86 | Basal | African | TCGA.A7.A6VV.01A.22R.A33J.07 |
| TCGA-A7-A6VX | 68 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.87 | LumB | African | TCGA.A7.A6VX.01A.12R.A33J.07 |
| TCGA-C8-A1HL | 38 | female | Asian | Primary solid Tumor | premenopausal | Infiltrating mucinous-papillary ductal carcinoma | positive | negative | equivocal | NA | NA | alive | 0.87 | NA | East Asian | TCGA.C8.A1HL.01A.11R.A137.07 |
| TCGA-A2-A25F | 66 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | positive | negative | NA | NA | alive | 0.88 | Basal | European | TCGA.A2.A25F.01A.11R.A169.07 |
| TCGA-A7-A3IZ | 62 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | equivocal | NA | NA | alive | 0.88 | NA | European | TCGA.A7.A3IZ.01A.11R.A213.07 |
| TCGA-LD-A9QF | 73 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 0.88 | Normal | African_admix | TCGA.LD.A9QF.01A.32R.A41B.07 |
| TCGA-BH-A28O | 50 | female | White | Primary solid Tumor | not available | ILC | positive | positive | negative | NA | NA | alive | 0.89 | NA | European | TCGA.BH.A28O.01A.11R.A22K.07 |
| TCGA-A7-A5ZW | 47 | female | Black or African American | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.89 | LumA | African_admix | TCGA.A7.A5ZW.01A.12R.A29R.07 |
| TCGA-BH-A0GZ | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 0.9 | LumA | European | TCGA.BH.A0GZ.01A.11R.A056.07 |
| TCGA-AC-A23G | 76 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 0.9 | NA | European | TCGA.AC.A23G.01A.11R.A213.07 |
| TCGA-C8-A1HF | 48 | female | Asian | Primary solid Tumor | premenopausal | IDC | negative | positive | positive | NA | NA | alive | 0.91 | Her2 | East Asian | TCGA.C8.A1HF.01A.11R.A137.07 |
| TCGA-A8-A07P | 68 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 0.91 | LumA | European | TCGA.A8.A07P.01A.11R.A00Z.07 |
| TCGA-A7-A5ZX | 48 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 0.92 | LumA | European | TCGA.A7.A5ZX.01A.12R.A29R.07 |
| TCGA-E2-A1IU | 60 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.92 | LumA | European | TCGA.E2.A1IU.01A.11R.A14D.07 |
| TCGA-C8-A1HI | 40 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.94 | LumA | East Asian | TCGA.C8.A1HI.01A.11R.A137.07 |
| TCGA-A7-A3IY | 71 | female | White | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | negative | NA | NA | alive | 0.94 | NA | European | TCGA.A7.A3IY.01A.21R.A21T.07 |
| TCGA-C8-A1HG | 50 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.94 | LumB | East Asian | TCGA.C8.A1HG.01A.11R.A137.07 |
| TCGA-W8-A86G | 66 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 0.95 | LumA | European | TCGA.W8.A86G.01A.21R.A36F.07 |
| TCGA-4H-AAAK | 50 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 0.95 | LumA | European | TCGA.4H.AAAK.01A.12R.A41B.07 |
| TCGA-AO-A1KS | 69 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 0.96 | LumB | European | TCGA.AO.A1KS.01A.11R.A13Q.07 |
| TCGA-JL-A3YX | 46 | female | Asian | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 0.96 | LumA | South Asian_admix | TCGA.JL.A3YX.01A.11R.A22U.07 |
| TCGA-BH-A0BW | 71 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | not available | NA | NA | alive | 0.97 | Basal | African_admix | TCGA.BH.A0BW.01A.11R.A115.07 |
| TCGA-BH-A0BW | 71 | female | Black or African American | Solid Tissue Normal | postmenopausal | IDC | negative | negative | not available | NA | NA | alive | 0.97 | Basal | African_admix | TCGA.BH.A0BW.11A.12R.A115.07 |
| TCGA-C8-A12M | 70 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 0.98 | LumB | East Asian | TCGA.C8.A12M.01A.11R.A115.07 |
| TCGA-C8-A12N | 58 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.98 | LumA | East Asian | TCGA.C8.A12N.01A.11R.A115.07 |
| TCGA-C8-A12P | 55 | female | Asian | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 0.98 | Her2 | East Asian | TCGA.C8.A12P.01A.11R.A115.07 |
| TCGA-JL-A3YW | 49 | female | Asian | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 0.99 | NA | South Asian | TCGA.JL.A3YW.01A.12R.A239.07 |
| TCGA-D8-A13Y | 52 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 0.99 | LumB | European | TCGA.D8.A13Y.01A.11R.A115.07 |
| TCGA-C8-A12L | 67 | female | Asian | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 0.99 | Her2 | East Asian | TCGA.C8.A12L.01A.11R.A115.07 |
| TCGA-A7-A426 | 50 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.0 | NA | European | TCGA.A7.A426.01A.22R.A24H.07 |
| TCGA-A8-A07J | 35 | female | not available | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.0 | LumA | European | TCGA.A8.A07J.01A.11R.A00Z.07 |
| TCGA-A8-A08I | 53 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.0 | LumB | European | TCGA.A8.A08I.01A.11R.A00Z.07 |
| TCGA-A8-A097 | 65 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.0 | LumA | European | TCGA.A8.A097.01A.11R.A034.07 |
| TCGA-A8-A09B | 58 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.0 | LumA | European | TCGA.A8.A09B.01A.11R.A00Z.07 |
| TCGA-A8-A0A1 | 84 | female | not available | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.0 | LumA | European | TCGA.A8.A0A1.01A.11R.A00Z.07 |
| TCGA-E9-A1N8 | 48 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | not evaluated | negative | NA | NA | alive | 1.0 | Basal | European | TCGA.E9.A1N8.01A.11R.A144.07 |
| TCGA-D8-A1JG | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 1.0 | Her2 | European | TCGA.D8.A1JG.01B.11R.A13Q.07 |
| TCGA-A7-A5ZV | 62 | female | Black or African American | Primary solid Tumor | postmenopausal | infiltrating carcinoma NOS | negative | negative | equivocal | NA | NA | alive | 1.01 | NA | African | TCGA.A7.A5ZV.01A.11R.A28M.07 |
| TCGA-D8-A1JS | 77 | female | White | Primary solid Tumor | postmenopausal | papillary | positive | positive | negative | NA | NA | alive | 1.02 | NA | European | TCGA.D8.A1JS.01A.11R.A13Q.07 |
| TCGA-EW-A1IW | 80 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 1.02 | LumA | European | TCGA.EW.A1IW.01A.11R.A13Q.07 |
| TCGA-A7-A0CD | 66 | female | White | Primary solid Tumor | indeterminate | IDC | positive | positive | equivocal | NA | NA | alive | 1.02 | LumA | European | TCGA.A7.A0CD.01A.11R.A00Z.07 |
| TCGA-A7-A0DA | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.02 | Basal | European | TCGA.A7.A0DA.01A.31R.A115.07 |
| TCGA-AC-A6IX | 49 | female | White | Primary solid Tumor | perimenopausal | ILC | positive | positive | not evaluated | NA | NA | alive | 1.02 | LumA | European | TCGA.AC.A6IX.01A.12R.A32P.07 |
| TCGA-D8-A27W | 55 | female | White | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | equivocal | NA | NA | alive | 1.02 | NA | European | TCGA.D8.A27W.01A.11R.A16F.07 |
| TCGA-AN-A0XO | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 1.03 | LumA | European | TCGA.AN.A0XO.01A.11R.A109.07 |
| TCGA-C8-A1HE | 59 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.03 | LumA | East Asian | TCGA.C8.A1HE.01A.11R.A13Q.07 |
| TCGA-C8-A1HO | 34 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.03 | LumA | East Asian | TCGA.C8.A1HO.01A.11R.A13Q.07 |
| TCGA-E9-A295 | 71 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 1.03 | LumA | European | TCGA.E9.A295.01A.11R.A16F.07 |
| TCGA-C8-A26X | 58 | female | Asian | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.03 | Her2 | East Asian | TCGA.C8.A26X.01A.31R.A16F.07 |
| TCGA-C8-A137 | 34 | female | Asian | Primary solid Tumor | premenopausal | IDC | negative | negative | positive | locoregional recurrence | not available | alive | 1.04 | Her2 | East Asian | TCGA.C8.A137.01A.11R.A115.07 |
| TCGA-E9-A228 | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 1.04 | LumB | European | TCGA.E9.A228.01A.31R.A157.07 |
| TCGA-C8-A12Z | 45 | female | Asian | Primary solid Tumor | perimenopausal | IDC | negative | negative | positive | NA | NA | alive | 1.05 | Her2 | East Asian | TCGA.C8.A12Z.01A.11R.A115.07 |
| TCGA-C8-A134 | 52 | female | Asian | Primary solid Tumor | perimenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 1.05 | Basal | East Asian | TCGA.C8.A134.01A.11R.A115.07 |
| TCGA-C8-A12O | 50 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.05 | LumA | East Asian | TCGA.C8.A12O.01A.11R.A115.07 |
| TCGA-C8-A12U | 46 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.05 | LumB | East Asian | TCGA.C8.A12U.01A.11R.A115.07 |
| TCGA-C8-A12V | 55 | female | Asian | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.05 | Basal | East Asian | TCGA.C8.A12V.01A.11R.A115.07 |
| TCGA-C8-A12X | 62 | female | Asian | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | negative | NA | NA | alive | 1.05 | NA | East Asian | TCGA.C8.A12X.01A.11R.A115.07 |
| TCGA-D8-A1XW | 53 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | positive | negative | NA | NA | alive | 1.05 | Normal | European | TCGA.D8.A1XW.01A.11R.A14M.07 |
| TCGA-BH-A0HU | 52 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.07 | LumB | European | TCGA.BH.A0HU.01A.11R.A034.07 |
| TCGA-C8-A135 | 64 | female | Asian | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 1.08 | Her2 | East Asian | TCGA.C8.A135.01A.11R.A115.07 |
| TCGA-LL-A5YM | 88 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | locoregional recurrence | skin chest wall | alive | 1.08 | LumB | African | TCGA.LL.A5YM.01A.11R.A28M.07 |
| TCGA-D8-A1XU | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.08 | LumA | European | TCGA.D8.A1XU.01A.11R.A14M.07 |
| TCGA-A8-A06O | 60 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.08 | LumB | European | TCGA.A8.A06O.01A.11R.A00Z.07 |
| TCGA-A8-A06P | 63 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.08 | LumA | European | TCGA.A8.A06P.01A.11R.A00Z.07 |
| TCGA-A8-A086 | 59 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.08 | LumA | European | TCGA.A8.A086.01A.11R.A00Z.07 |
| TCGA-A8-A09D | 47 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.08 | LumA | European | TCGA.A8.A09D.01A.11R.A00Z.07 |
| TCGA-A8-A0A4 | 73 | female | not available | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.08 | LumA | European | TCGA.A8.A0A4.01A.11R.A00Z.07 |
| TCGA-D8-A27H | 72 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.09 | Basal | European | TCGA.D8.A27H.01A.11R.A16F.07 |
| TCGA-D8-A27T | 53 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.09 | LumA | European | TCGA.D8.A27T.01A.11R.A16F.07 |
| TCGA-E9-A1N9 | 58 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | negative | positive | positive | NA | NA | alive | 1.09 | NA | European | TCGA.E9.A1N9.01A.11R.A14D.07 |
| TCGA-E9-A1N9 | 58 | female | White | Solid Tissue Normal | postmenopausal | IDC/ILC | negative | positive | positive | NA | NA | alive | 1.09 | NA | European | TCGA.E9.A1N9.11A.71R.A14D.07 |
| TCGA-E9-A22D | 38 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.1 | LumB | European | TCGA.E9.A22D.01A.11R.A157.07 |
| TCGA-LD-A74U | 79 | female | White | Primary solid Tumor | not available | \ILC, classical type, focal pleomorphic type\"" | positive | negative | negative | NA | NA | alive | 1.1 | NA | European | TCGA.LD.A74U.01A.13R.A33J.07 |
| TCGA-D8-A140 | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.1 | LumA | European | TCGA.D8.A140.01A.11R.A115.07 |
| TCGA-EW-A1J2 | 50 | female | Black or African American | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.1 | LumA | South Asian | TCGA.EW.A1J2.01A.21R.A13Q.07 |
| TCGA-LD-A7W6 | 54 | female | White | Primary solid Tumor | postmenopausal | \ILC, mixed classical (70%) and pleomorphic/solid (30%) types\"" | positive | positive | negative | NA | NA | alive | 1.11 | NA | European | TCGA.LD.A7W6.01A.81R.A352.07 |
| TCGA-D8-A1JT | 70 | female | White | Primary solid Tumor | postmenopausal | ductal and papillary | positive | positive | equivocal | NA | NA | alive | 1.11 | NA | European | TCGA.D8.A1JT.01A.31R.A13Q.07 |
| TCGA-E9-A229 | 37 | female | White | Primary solid Tumor | premenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 1.11 | LumA | European | TCGA.E9.A229.01A.31R.A157.07 |
| TCGA-C8-A8HR | 49 | female | Asian | Primary solid Tumor | perimenopausal | ILC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 1.12 | Normal | East Asian | TCGA.C8.A8HR.01A.11R.A36F.07 |
| TCGA-D8-A27G | 75 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 1.12 | LumA | European | TCGA.D8.A27G.01A.11R.A16F.07 |
| TCGA-D8-A27M | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.12 | Basal | European | TCGA.D8.A27M.01A.11R.A16F.07 |
| TCGA-GM-A5PV | 63 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | NA | NA | alive | 1.13 | LumA | European | TCGA.GM.A5PV.01A.11R.A28M.07 |
| TCGA-AC-A6IW | 73 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.13 | Basal | African | TCGA.AC.A6IW.01A.12R.A33J.07 |
| TCGA-BH-A0HP | 65 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | negative | NA | NA | alive | 1.13 | LumA | European | TCGA.BH.A0HP.01A.12R.A084.07 |
| TCGA-A1-A0SJ | 39 | female | Black or African American | Primary solid Tumor | not available | IDC | positive | positive | equivocal | NA | NA | alive | 1.14 | LumA | African_admix | TCGA.A1.A0SJ.01A.11R.A084.07 |
| TCGA-AC-A62X | 72 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | not evaluated | NA | NA | alive | 1.14 | Basal | African | TCGA.AC.A62X.01A.11R.A29R.07 |
| TCGA-A7-A4SB | 56 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.14 | NA | European | TCGA.A7.A4SB.01A.21R.A266.07 |
| TCGA-E9-A1NE | 28 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.15 | LumA | European | TCGA.E9.A1NE.01A.21R.A14M.07 |
| TCGA-S3-AA11 | 67 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.15 | LumA | African | TCGA.S3.AA11.01A.31R.A41B.07 |
| TCGA-BH-A0DK | 49 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.16 | LumA | European | TCGA.BH.A0DK.01A.21R.A056.07 |
| TCGA-BH-A0DK | 49 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.16 | LumA | European | TCGA.BH.A0DK.11A.13R.A089.07 |
| TCGA-EW-A1PD | 61 | male | White | Primary solid Tumor | not applicable | IDC | positive | positive | equivocal | NA | NA | alive | 1.16 | NA | European | TCGA.EW.A1PD.01A.11R.A144.07 |
| TCGA-S3-AA17 | 64 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.16 | LumB | African_admix | TCGA.S3.AA17.01A.11R.A41B.07 |
| TCGA-A8-A07I | 69 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | NA | NA | alive | 1.17 | Her2 | European | TCGA.A8.A07I.01A.11R.A00Z.07 |
| TCGA-D8-A1JH | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.17 | LumA | European | TCGA.D8.A1JH.01A.11R.A13Q.07 |
| TCGA-E2-A15S | 34 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | equivocal | NA | NA | alive | 1.17 | LumB | European | TCGA.E2.A15S.01A.11R.A115.07 |
| TCGA-D8-A1Y3 | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | Indeterminate | NA | NA | alive | 1.18 | LumB | European | TCGA.D8.A1Y3.01A.11R.A157.07 |
| TCGA-D8-A143 | 51 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.18 | Basal | European | TCGA.D8.A143.01A.11R.A115.07 |
| TCGA-D8-A1J8 | 77 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.18 | LumB | European | TCGA.D8.A1J8.01A.11R.A13Q.07 |
| TCGA-A1-A0SG | 61 | female | White | Primary solid Tumor | postmenopausal | micropapillary carcinoma invasive | positive | positive | negative | NA | NA | alive | 1.19 | NA | European | TCGA.A1.A0SG.01A.11R.A144.07 |
| TCGA-BH-A0E2 | 49 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.19 | LumA | African | TCGA.BH.A0E2.01A.11R.A056.07 |
| TCGA-A1-A0SD | 59 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | alive | 1.2 | LumA | European | TCGA.A1.A0SD.01A.11R.A115.07 |
| TCGA-C8-A27B | 48 | female | Asian | Primary solid Tumor | perimenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.2 | Basal | East Asian | TCGA.C8.A27B.01A.11R.A169.07 |
| TCGA-D8-A27I | 58 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.2 | LumA | European | TCGA.D8.A27I.01A.11R.A16F.07 |
| TCGA-A2-A0YI | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.21 | LumA | European | TCGA.A2.A0YI.01A.31R.A10J.07 |
| TCGA-A7-A4SD | 52 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 1.21 | Basal | African | TCGA.A7.A4SD.01A.11R.A266.07 |
| TCGA-D8-A1XK | 55 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.21 | Basal | European | TCGA.D8.A1XK.01A.21R.A14M.07 |
| TCGA-D8-A3Z5 | 54 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.21 | NA | European | TCGA.D8.A3Z5.01A.41R.A24H.07 |
| TCGA-LL-A740 | 61 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 1.21 | LumA | African | TCGA.LL.A740.01A.21R.A32P.07 |
| TCGA-A2-A0YL | 48 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.22 | LumA | European | TCGA.A2.A0YL.01A.21R.A109.07 |
| TCGA-A7-A4SC | 62 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | equivocal | NA | NA | alive | 1.22 | NA | European | TCGA.A7.A4SC.01A.12R.A266.07 |
| TCGA-A7-A425 | 70 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | Indeterminate | locoregional recurrence | breast>bone | alive | 1.22 | LumA | European | TCGA.A7.A425.01A.11R.A24H.07 |
| TCGA-D8-A1JU | 51 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.22 | LumA | European | TCGA.D8.A1JU.01A.11R.A13Q.07 |
| TCGA-LL-A5YN | 46 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.22 | LumA | African | TCGA.LL.A5YN.01A.11R.A28M.07 |
| TCGA-A7-A56D | 84 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.23 | LumA | African | TCGA.A7.A56D.01A.11R.A27Q.07 |
| TCGA-E2-A158 | 43 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.23 | Basal | European | TCGA.E2.A158.01A.11R.A12D.07 |
| TCGA-E2-A158 | 43 | female | White | Solid Tissue Normal | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.23 | Basal | European | TCGA.E2.A158.11A.22R.A12D.07 |
| TCGA-AC-A3OD | 68 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.23 | LumA | European | TCGA.AC.A3OD.01A.11R.A21T.07 |
| TCGA-A7-A4SA | 40 | female | White | Primary solid Tumor | premenopausal | ILC | positive | negative | negative | NA | NA | alive | 1.24 | NA | European | TCGA.A7.A4SA.01A.11R.A266.07 |
| TCGA-AC-A3TN | 75 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 1.25 | NA | European | TCGA.AC.A3TN.01A.11R.A22K.07 |
| TCGA-E2-A15T | 65 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.25 | LumB | European | TCGA.E2.A15T.01A.11R.A115.07 |
| TCGA-A8-A09M | 75 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.25 | LumB | European | TCGA.A8.A09M.01A.11R.A00Z.07 |
| TCGA-A8-A09V | 51 | female | not available | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.25 | LumA | European | TCGA.A8.A09V.01A.11R.A034.07 |
| TCGA-A8-A084 | 81 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 1.25 | NA | European | TCGA.A8.A084.01A.21R.A00Z.07 |
| TCGA-BH-A0H0 | 69 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.26 | LumB | European | TCGA.BH.A0H0.01A.11R.A056.07 |
| TCGA-D8-A1XV | 84 | female | White | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | equivocal | NA | NA | alive | 1.26 | NA | European | TCGA.D8.A1XV.01A.11R.A14M.07 |
| TCGA-EW-A6S9 | 34 | female | Black or African American | Primary solid Tumor | not available | IDC | positive | positive | positive | NA | NA | alive | 1.27 | LumA | African_admix | TCGA.EW.A6S9.01A.22R.A33J.07 |
| TCGA-D8-A1XZ | 81 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 1.28 | LumB | European | TCGA.D8.A1XZ.01A.11R.A14M.07 |
| TCGA-XX-A899 | 46 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.28 | LumA | European | TCGA.XX.A899.01A.11R.A36F.07 |
| TCGA-A2-A0YF | 67 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 1.28 | LumA | African_admix | TCGA.A2.A0YF.01A.21R.A109.07 |
| TCGA-C8-A26Z | 59 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.29 | LumA | East Asian | TCGA.C8.A26Z.01A.11R.A16F.07 |
| TCGA-E2-A1LS | 46 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.29 | NA | European | TCGA.E2.A1LS.01A.12R.A157.07 |
| TCGA-E2-A1LS | 46 | female | White | Solid Tissue Normal | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.29 | NA | European | TCGA.E2.A1LS.11A.32R.A157.07 |
| TCGA-AC-A3W7 | 66 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | negative | NA | NA | alive | 1.29 | NA | European | TCGA.AC.A3W7.01A.11R.A22K.07 |
| TCGA-D8-A1Y0 | 65 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.29 | LumA | European | TCGA.D8.A1Y0.01A.11R.A14M.07 |
| TCGA-D8-A1XO | 56 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.3 | LumA | European | TCGA.D8.A1XO.01A.11R.A14M.07 |
| TCGA-AQ-A1H2 | 84 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | Indeterminate | NA | NA | alive | 1.3 | LumA | European | TCGA.AQ.A1H2.01A.11R.A13Q.07 |
| TCGA-BH-A0DP | 60 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.3 | LumA | European | TCGA.BH.A0DP.01A.21R.A056.07 |
| TCGA-BH-A0DP | 60 | female | White | Solid Tissue Normal | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.3 | LumA | European | TCGA.BH.A0DP.11A.12R.A089.07 |
| TCGA-BH-A0E1 | 52 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.31 | LumA | European | TCGA.BH.A0E1.01A.11R.A056.07 |
| TCGA-BH-A0E1 | 52 | female | White | Solid Tissue Normal | perimenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.31 | LumA | European | TCGA.BH.A0E1.11A.13R.A089.07 |
| TCGA-EW-A1J5 | 59 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.31 | LumA | European | TCGA.EW.A1J5.01A.11R.A13Q.07 |
| TCGA-LL-A73Y | 67 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.31 | Basal | African | TCGA.LL.A73Y.01A.11R.A33J.07 |
| TCGA-E2-A3DX | 43 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | not evaluated | NA | NA | alive | 1.31 | NA | European | TCGA.E2.A3DX.01A.21R.A213.07 |
| TCGA-D8-A1JC | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.31 | LumB | European | TCGA.D8.A1JC.01A.11R.A13Q.07 |
| TCGA-D8-A1XR | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.32 | LumB | European | TCGA.D8.A1XR.01A.11R.A14M.07 |
| TCGA-A2-A0EY | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | NA | NA | alive | 1.33 | LumB | European | TCGA.A2.A0EY.01A.11R.A034.07 |
| TCGA-E2-A14P | 79 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 1.33 | Her2 | European | TCGA.E2.A14P.01A.31R.A12D.07 |
| TCGA-AR-A5QN | 68 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 1.34 | LumA | European | TCGA.AR.A5QN.01A.12R.A28M.07 |
| TCGA-D8-A27F | 40 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.34 | Basal | European | TCGA.D8.A27F.01A.11R.A16F.07 |
| TCGA-XX-A89A | 68 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.34 | LumA | European | TCGA.XX.A89A.01A.11R.A36F.07 |
| TCGA-LL-A6FR | 50 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | positive | equivocal | NA | NA | alive | 1.34 | Basal | African | TCGA.LL.A6FR.01A.12R.A31O.07 |
| TCGA-D8-A73U | 88 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.35 | LumA | European | TCGA.D8.A73U.01A.11R.A33J.07 |
| TCGA-BH-A0DZ | 43 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.36 | LumA | European | TCGA.BH.A0DZ.01A.11R.A00Z.07 |
| TCGA-BH-A0DZ | 43 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.36 | LumA | European | TCGA.BH.A0DZ.11A.22R.A089.07 |
| TCGA-A2-A25B | 39 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | metastasis | bone | alive | 1.36 | LumB | African | TCGA.A2.A25B.01A.11R.A169.07 |
| TCGA-AC-A3HN | 87 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.36 | LumA | European | TCGA.AC.A3HN.01A.11R.A213.07 |
| TCGA-D8-A1XQ | 69 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.37 | Basal | European | TCGA.D8.A1XQ.01A.11R.A14M.07 |
| TCGA-D8-A27L | 49 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.37 | LumA | European | TCGA.D8.A27L.01A.11R.A16F.07 |
| TCGA-A2-A1G6 | 50 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.37 | Normal | European | TCGA.A2.A1G6.01A.11R.A13Q.07 |
| TCGA-E2-A1BC | 63 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.37 | LumA | European | TCGA.E2.A1BC.01A.11R.A12P.07 |
| TCGA-E2-A1BC | 63 | female | not available | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.37 | LumA | European | TCGA.E2.A1BC.11A.32R.A12P.07 |
| TCGA-D8-A1JA | 60 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | locoregional disease | NA | alive | 1.37 | Her2 | European | TCGA.D8.A1JA.01A.11R.A13Q.07 |
| TCGA-EW-A1J3 | 61 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 1.38 | LumA | European | TCGA.EW.A1J3.01A.11R.A13Q.07 |
| TCGA-D8-A1XT | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 1.39 | Her2 | European | TCGA.D8.A1XT.01A.11R.A14M.07 |
| TCGA-C8-A274 | 63 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.39 | LumB | East Asian | TCGA.C8.A274.01A.11R.A16F.07 |
| TCGA-E9-A1N5 | 45 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | positive | positive | positive | NA | NA | alive | 1.39 | NA | European | TCGA.E9.A1N5.01A.11R.A14D.07 |
| TCGA-E9-A1N5 | 45 | female | White | Solid Tissue Normal | postmenopausal | IDC/ILC | positive | positive | positive | NA | NA | alive | 1.39 | NA | European | TCGA.E9.A1N5.11A.41R.A14D.07 |
| TCGA-EW-A6SA | 59 | male | Black or African American | Primary solid Tumor | not applicable | IDC | positive | negative | negative | NA | NA | alive | 1.4 | NA | African | TCGA.EW.A6SA.01A.21R.A32P.07 |
| TCGA-BH-A0HN | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.41 | NA | European | TCGA.BH.A0HN.01A.11R.A10U.07 |
| TCGA-A8-A075 | 42 | female | not available | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.42 | LumB | European | TCGA.A8.A075.01A.11R.A084.07 |
| TCGA-A8-A0AB | 54 | female | not available | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 1.42 | LumA | European | TCGA.A8.A0AB.01A.11R.A034.07 |
| TCGA-UL-AAZ6 | 73 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.42 | LumA | African | TCGA.UL.AAZ6.01A.11R.A41B.07 |
| TCGA-D8-A27N | 36 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.42 | LumB | European | TCGA.D8.A27N.01A.11R.A16F.07 |
| TCGA-E2-A15R | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.42 | LumA | European | TCGA.E2.A15R.01A.11R.A115.07 |
| TCGA-LL-A5YL | 64 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | positive | NA | NA | alive | 1.42 | LumA | European | TCGA.LL.A5YL.01A.12R.A29R.07 |
| TCGA-E2-A1BD | 53 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.42 | LumA | European | TCGA.E2.A1BD.01A.11R.A12P.07 |
| TCGA-D8-A1XD | 36 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.43 | NA | European | TCGA.D8.A1XD.01A.11R.A14D.07 |
| TCGA-A2-A25C | 50 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.43 | LumB | European | TCGA.A2.A25C.01A.11R.A169.07 |
| TCGA-BH-A0DO | 78 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.44 | LumA | European | TCGA.BH.A0DO.01B.11R.A12D.07 |
| TCGA-BH-A0DO | 78 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.44 | LumA | European | TCGA.BH.A0DO.11A.22R.A12D.07 |
| TCGA-S3-AA15 | 51 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.44 | Basal | African | TCGA.S3.AA15.01A.11R.A41B.07 |
| TCGA-E2-A15D | 47 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.44 | LumA | European | TCGA.E2.A15D.01A.11R.A115.07 |
| TCGA-A2-A1FW | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 1.45 | LumB | European | TCGA.A2.A1FW.01A.11R.A13Q.07 |
| TCGA-OL-A66O | 39 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 1.45 | LumA | African | TCGA.OL.A66O.01A.11R.A31O.07 |
| TCGA-S3-AA14 | 47 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.45 | LumA | African | TCGA.S3.AA14.01A.11R.A41B.07 |
| TCGA-D8-A27E | 66 | female | White | Primary solid Tumor | postmenopausal | IDC/mucinous | positive | positive | negative | NA | NA | alive | 1.45 | NA | European | TCGA.D8.A27E.01A.11R.A16F.07 |
| TCGA-E2-A15I | 44 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.45 | LumA | European | TCGA.E2.A15I.01A.21R.A137.07 |
| TCGA-E2-A15I | 44 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.45 | LumA | European | TCGA.E2.A15I.11A.32R.A137.07 |
| TCGA-A2-A0T5 | 39 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.45 | LumA | European | TCGA.A2.A0T5.01A.21R.A084.07 |
| TCGA-D8-A1J9 | 48 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | NA | NA | alive | 1.46 | LumB | European | TCGA.D8.A1J9.01A.11R.A13Q.07 |
| TCGA-EW-A3U0 | 61 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.46 | NA | African_admix | TCGA.EW.A3U0.01A.11R.A22K.07 |
| TCGA-LL-A9Q3 | 69 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 1.46 | LumA | European | TCGA.LL.A9Q3.01A.11R.A41B.07 |
| TCGA-A2-A0T0 | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.46 | Basal | European | TCGA.A2.A0T0.01A.22R.A084.07 |
| TCGA-D8-A1XM | 57 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.47 | LumA | European | TCGA.D8.A1XM.01A.21R.A14M.07 |
| TCGA-AO-A1KT | 78 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.48 | LumB | European | TCGA.AO.A1KT.01A.11R.A13Q.07 |
| TCGA-D8-A1X6 | 80 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.48 | LumB | European | TCGA.D8.A1X6.01A.11R.A14M.07 |
| TCGA-E9-A1N3 | 70 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 1.48 | NA | European | TCGA.E9.A1N3.01A.12R.A157.07 |
| TCGA-BH-A0W5 | 77 | female | White | Primary solid Tumor | not available | IDC | positive | positive | equivocal | NA | NA | alive | 1.49 | LumA | European | TCGA.BH.A0W5.01A.11R.A109.07 |
| TCGA-A7-A4SF | 54 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | NA | NA | alive | 1.49 | NA | African | TCGA.A7.A4SF.01A.11R.A266.07 |
| TCGA-A8-A093 | 61 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.49 | LumA | European | TCGA.A8.A093.01A.11R.A00Z.07 |
| TCGA-A8-A06R | 69 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | NA | NA | alive | 1.5 | LumB | European | TCGA.A8.A06R.01A.11R.A00Z.07 |
| TCGA-A8-A082 | 58 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.5 | LumB | European | TCGA.A8.A082.01A.11R.A00Z.07 |
| TCGA-A8-A08F | 59 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.5 | NA | European | TCGA.A8.A08F.01A.11R.A00Z.07 |
| TCGA-GM-A5PX | 65 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.51 | LumA | European | TCGA.GM.A5PX.01A.12R.A28M.07 |
| TCGA-D8-A1JD | 41 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.51 | LumB | European | TCGA.D8.A1JD.01A.11R.A13Q.07 |
| TCGA-D8-A1XB | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.51 | LumA | European | TCGA.D8.A1XB.01A.11R.A14D.07 |
| TCGA-A1-A0SQ | 45 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.52 | LumA | European | TCGA.A1.A0SQ.01A.21R.A144.07 |
| TCGA-A2-A0YE | 48 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.52 | Basal | European | TCGA.A2.A0YE.01A.11R.A109.07 |
| TCGA-BH-A0BD | 47 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.52 | LumB | European | TCGA.BH.A0BD.01A.11R.A034.07 |
| TCGA-E2-A15G | 76 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | positive | positive | negative | NA | NA | alive | 1.52 | NA | European | TCGA.E2.A15G.01A.11R.A12D.07 |
| TCGA-BH-A0W7 | 49 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | alive | 1.53 | LumA | European | TCGA.BH.A0W7.01A.11R.A115.07 |
| TCGA-E9-A3Q9 | 78 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | Indeterminate | NA | NA | alive | 1.53 | NA | European | TCGA.E9.A3Q9.01A.11R.A21T.07 |
| TCGA-EW-A1P6 | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.54 | LumA | European | TCGA.EW.A1P6.01A.11R.A144.07 |
| TCGA-S3-A6ZG | 71 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC/ILC | positive | positive | negative | NA | NA | alive | 1.54 | NA | African_admix | TCGA.S3.A6ZG.01A.22R.A32P.07 |
| TCGA-D8-A3Z6 | 56 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.54 | LumA | European | TCGA.D8.A3Z6.01A.11R.A239.07 |
| TCGA-D8-A1X5 | 81 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.55 | LumB | European | TCGA.D8.A1X5.01A.11R.A14D.07 |
| TCGA-A2-A0YJ | 39 | female | White | Primary solid Tumor | premenopausal | IDC | positive | negative | negative | metastasis | cervical lymph node | alive | 1.55 | Basal | European | TCGA.A2.A0YJ.01A.11R.A109.07 |
| TCGA-AC-A6IV | 47 | female | White | Primary solid Tumor | not available | ILC | positive | positive | equivocal | NA | NA | alive | 1.56 | LumA | European | TCGA.AC.A6IV.01A.12R.A33J.07 |
| TCGA-A2-A0T3 | 37 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.56 | LumB | European | TCGA.A2.A0T3.01A.21R.A115.07 |
| TCGA-D8-A1JB | 54 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.56 | LumA | European | TCGA.D8.A1JB.01A.11R.A13Q.07 |
| TCGA-S3-A6ZF | 64 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.57 | LumB | African | TCGA.S3.A6ZF.01A.32R.A32P.07 |
| TCGA-BH-A8FZ | 58 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 1.57 | Normal | European | TCGA.BH.A8FZ.01A.11R.A352.07 |
| TCGA-E2-A1LG | 50 | female | Black or African American | Primary solid Tumor | perimenopausal | ILC | negative | negative | equivocal | NA | NA | alive | 1.57 | Basal | African | TCGA.E2.A1LG.01A.21R.A14M.07 |
| TCGA-S3-AA12 | 82 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | metastasis | lung|adrenal gland | alive | 1.57 | LumA | African | TCGA.S3.AA12.01A.11R.A41B.07 |
| TCGA-A2-A0T6 | 50 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.57 | LumA | European | TCGA.A2.A0T6.01A.11R.A084.07 |
| TCGA-D8-A1JE | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.57 | LumB | European | TCGA.D8.A1JE.01A.11R.A13Q.07 |
| TCGA-EW-A1PA | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.57 | LumA | European | TCGA.EW.A1PA.01A.11R.A144.07 |
| TCGA-E9-A1NH | 71 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.58 | LumA | European | TCGA.E9.A1NH.01A.11R.A14D.07 |
| TCGA-A8-A07F | 65 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.58 | LumA | European | TCGA.A8.A07F.01A.11R.A00Z.07 |
| TCGA-A8-A07G | 65 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.58 | LumA | European | TCGA.A8.A07G.01A.11R.A034.07 |
| TCGA-D8-A1JI | 54 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.58 | LumB | European | TCGA.D8.A1JI.01A.11R.A13Q.07 |
| TCGA-E2-A576 | 69 | female | Black or African American | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 1.58 | LumA | African | TCGA.E2.A576.01A.11R.A31O.07 |
| TCGA-A8-A09T | 68 | female | not available | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.59 | LumA | European | TCGA.A8.A09T.01A.11R.A00Z.07 |
| TCGA-A8-A0A2 | 66 | female | not available | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.59 | LumA | European | TCGA.A8.A0A2.01A.11R.A034.07 |
| TCGA-A8-A07C | 57 | female | not available | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.59 | NA | European | TCGA.A8.A07C.01A.11R.A034.07 |
| TCGA-A8-A08S | 71 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.59 | NA | European | TCGA.A8.A08S.01A.11R.A034.07 |
| TCGA-A8-A091 | 61 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | not available | NA | alive | 1.59 | LumA | European | TCGA.A8.A091.01A.11R.A00Z.07 |
| TCGA-A1-A0SP | 40 | female | not available | Primary solid Tumor | not available | IDC | negative | negative | negative | NA | NA | alive | 1.6 | Basal | European | TCGA.A1.A0SP.01A.11R.A084.07 |
| TCGA-A2-A1G1 | 85 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 1.6 | Basal | European | TCGA.A2.A1G1.01A.21R.A13Q.07 |
| TCGA-D8-A147 | 45 | female | White | Primary solid Tumor | indeterminate | IDC | negative | negative | negative | NA | NA | alive | 1.6 | Basal | European | TCGA.D8.A147.01A.11R.A115.07 |
| TCGA-AC-A23C | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.6 | LumA | European | TCGA.AC.A23C.01A.12R.A169.07 |
| TCGA-S3-AA10 | 65 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.6 | Basal | African | TCGA.S3.AA10.01A.21R.A41B.07 |
| TCGA-A2-A0YK | 61 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | negative | NA | NA | alive | 1.61 | Normal | European | TCGA.A2.A0YK.01A.22R.A109.07 |
| TCGA-AC-A2QI | 76 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | negative | NA | NA | alive | 1.61 | NA | European | TCGA.AC.A2QI.01A.12R.A19W.07 |
| TCGA-AC-A5XS | 74 | female | White | Primary solid Tumor | not available | ILC | positive | positive | negative | NA | NA | alive | 1.61 | LumA | European | TCGA.AC.A5XS.01A.11R.A29R.07 |
| TCGA-D8-A1JM | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 1.62 | Basal | European | TCGA.D8.A1JM.01A.11R.A13Q.07 |
| TCGA-E2-A15J | 51 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.62 | LumA | European | TCGA.E2.A15J.01A.11R.A12P.07 |
| TCGA-E2-A154 | 68 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.62 | LumA | European | TCGA.E2.A154.01A.11R.A115.07 |
| TCGA-LL-A7SZ | 49 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.63 | LumA | African | TCGA.LL.A7SZ.01A.32R.A352.07 |
| TCGA-A2-A1G4 | 71 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.63 | LumB | European | TCGA.A2.A1G4.01A.11R.A13Q.07 |
| TCGA-E2-A15P | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.63 | LumA | European | TCGA.E2.A15P.01A.11R.A115.07 |
| TCGA-LL-A8F5 | 61 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 1.63 | Basal | African | TCGA.LL.A8F5.01A.11R.A36F.07 |
| TCGA-E2-A1L9 | 40 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.64 | LumA | European | TCGA.E2.A1L9.01A.11R.A13Q.07 |
| TCGA-D8-A1XL | 34 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.66 | LumB | European | TCGA.D8.A1XL.01A.11R.A14M.07 |
| TCGA-A8-A08G | 41 | female | not available | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.66 | LumB | European | TCGA.A8.A08G.01A.11R.A00Z.07 |
| TCGA-EW-A1PH | 52 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.66 | Basal | European | TCGA.EW.A1PH.01A.11R.A14M.07 |
| TCGA-A8-A07E | 81 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.66 | LumA | European | TCGA.A8.A07E.01A.11R.A034.07 |
| TCGA-EW-A1PB | 70 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.66 | Basal | African | TCGA.EW.A1PB.01A.11R.A144.07 |
| TCGA-D8-A1JJ | 54 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.67 | LumB | European | TCGA.D8.A1JJ.01A.31R.A14M.07 |
| TCGA-D8-A1JL | 72 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.67 | Basal | European | TCGA.D8.A1JL.01A.11R.A13Q.07 |
| TCGA-BH-A2L8 | 45 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.68 | LumA | European | TCGA.BH.A2L8.01A.11R.A18M.07 |
| TCGA-AC-A8OP | 72 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | Indeterminate | NA | NA | alive | 1.68 | LumA | African | TCGA.AC.A8OP.01A.11R.A36F.07 |
| TCGA-AR-A1AY | 65 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.68 | Basal | European | TCGA.AR.A1AY.01A.21R.A12P.07 |
| TCGA-A2-A1G0 | 49 | female | White | Primary solid Tumor | premenopausal | Infiltrating Tubulolobular Carcinoma | positive | positive | equivocal | NA | NA | alive | 1.69 | NA | European | TCGA.A2.A1G0.01A.11R.A13Q.07 |
| TCGA-AO-A0J7 | 71 | female | White | Primary solid Tumor | postmenopausal | ductal/mucinous | positive | positive | negative | NA | NA | alive | 1.69 | NA | European | TCGA.AO.A0J7.01A.11R.A034.07 |
| TCGA-BH-A0HI | 78 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.7 | LumA | European | TCGA.BH.A0HI.01A.11R.A084.07 |
| TCGA-D8-A1JN | 80 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | Indeterminate | NA | NA | alive | 1.7 | LumA | European | TCGA.D8.A1JN.01A.11R.A13Q.07 |
| TCGA-OL-A5S0 | 66 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | not evaluated | NA | NA | alive | 1.7 | Basal | African_admix | TCGA.OL.A5S0.01A.11R.A28M.07 |
| TCGA-AO-A1KO | 46 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.7 | Normal | European | TCGA.AO.A1KO.01A.31R.A13Q.07 |
| TCGA-AR-A5QP | 54 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 1.7 | LumA | European | TCGA.AR.A5QP.01A.11R.A28M.07 |
| TCGA-BH-A0AW | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | NA | NA | alive | 1.7 | Her2 | European | TCGA.BH.A0AW.01A.11R.A056.07 |
| TCGA-A2-A0T4 | 62 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 1.71 | LumA | European | TCGA.A2.A0T4.01A.31R.A084.07 |
| TCGA-D8-A141 | 40 | female | White | Primary solid Tumor | indeterminate | IDC | positive | positive | negative | NA | NA | alive | 1.71 | LumA | European | TCGA.D8.A141.01A.11R.A115.07 |
| TCGA-E2-A15L | 65 | female | Black or African American | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 1.71 | LumA | African | TCGA.E2.A15L.01A.11R.A12D.07 |
| TCGA-E9-A1RH | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 1.71 | Her2 | European | TCGA.E9.A1RH.01A.21R.A169.07 |
| TCGA-E9-A1RH | 63 | female | White | Solid Tissue Normal | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 1.71 | Her2 | European | TCGA.E9.A1RH.11A.34R.A169.07 |
| TCGA-S3-AA0Z | 63 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.72 | Basal | African | TCGA.S3.AA0Z.01A.11R.A41B.07 |
| TCGA-E2-A15E | 40 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 1.72 | LumA | European | TCGA.E2.A15E.01A.11R.A12D.07 |
| TCGA-E9-A22H | 42 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.72 | LumB | European_admix | TCGA.E9.A22H.01A.11R.A157.07 |
| TCGA-A2-A0T7 | 51 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.73 | LumA | European | TCGA.A2.A0T7.01A.21R.A084.07 |
| TCGA-A1-A0SI | 52 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | alive | 1.74 | LumB | European | TCGA.A1.A0SI.01A.11R.A144.07 |
| TCGA-A2-A3KC | 55 | female | Black or African American | Primary solid Tumor | premenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 1.74 | NA | African_admix | TCGA.A2.A3KC.01A.11R.A213.07 |
| TCGA-BH-A42V | 41 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.74 | LumA | African | TCGA.BH.A42V.01A.11R.A24H.07 |
| TCGA-D8-A13Z | 51 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.74 | Her2 | European | TCGA.D8.A13Z.01A.11R.A115.07 |
| TCGA-D8-A1JP | 73 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.75 | LumA | European | TCGA.D8.A1JP.01A.11R.A13Q.07 |
| TCGA-A8-A0A6 | 64 | female | not available | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.75 | LumA | European | TCGA.A8.A0A6.01A.12R.A056.07 |
| TCGA-E2-A155 | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 1.75 | LumB | European | TCGA.E2.A155.01A.11R.A12D.07 |
| TCGA-S3-A6ZH | 29 | female | Black or African American | Primary solid Tumor | unknown | IDC | positive | positive | equivocal | NA | NA | alive | 1.75 | LumA | African | TCGA.S3.A6ZH.01A.22R.A32P.07 |
| TCGA-A2-A0D0 | 60 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.76 | Basal | African | TCGA.A2.A0D0.01A.11R.A00Z.07 |
| TCGA-A2-A4S2 | 62 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.76 | LumA | European | TCGA.A2.A4S2.01A.12R.A266.07 |
| TCGA-D8-A146 | 57 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.76 | NA | European | TCGA.D8.A146.01A.31R.A115.07 |
| TCGA-A7-A4SE | 54 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.76 | Basal | African | TCGA.A7.A4SE.01A.11R.A266.07 |
| TCGA-E9-A1R7 | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 1.77 | LumB | European | TCGA.E9.A1R7.01A.11R.A14M.07 |
| TCGA-E9-A1R7 | 64 | female | White | Solid Tissue Normal | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 1.77 | LumB | European | TCGA.E9.A1R7.11A.42R.A14M.07 |
| TCGA-LD-A66U | 44 | female | White | Primary solid Tumor | not evaluated | ILC | positive | positive | negative | NA | NA | alive | 1.77 | LumA | European | TCGA.LD.A66U.01A.11R.A31O.07 |
| TCGA-E9-A1RG | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 1.77 | LumB | European | TCGA.E9.A1RG.01A.11R.A14D.07 |
| TCGA-EW-A3E8 | 60 | female | White | Primary solid Tumor | not evaluated | ILC | positive | negative | negative | NA | NA | alive | 1.77 | NA | European | TCGA.EW.A3E8.01B.11R.A24H.07 |
| TCGA-A2-A4RY | 46 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.77 | NA | European | TCGA.A2.A4RY.01A.31R.A266.07 |
| TCGA-AO-A0JF | 68 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.78 | LumA | European | TCGA.AO.A0JF.01A.11R.A056.07 |
| TCGA-AO-A0J3 | 67 | female | White | Primary solid Tumor | postmenopausal | neuroendocrine and ductal | positive | positive | equivocal | NA | NA | alive | 1.78 | NA | European | TCGA.AO.A0J3.01A.11R.A034.07 |
| TCGA-BH-A18H | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.79 | LumA | European | TCGA.BH.A18H.01A.11R.A12D.07 |
| TCGA-E9-A1NA | 58 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | positive | positive | positive | NA | NA | alive | 1.79 | NA | European | TCGA.E9.A1NA.01A.11R.A144.07 |
| TCGA-E9-A1NA | 58 | female | White | Solid Tissue Normal | postmenopausal | IDC/ILC | positive | positive | positive | NA | NA | alive | 1.79 | NA | European | TCGA.E9.A1NA.11A.33R.A144.07 |
| TCGA-AO-A0JA | 36 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | metastasis | bone | alive | 1.79 | LumA | African_admix | TCGA.AO.A0JA.01A.11R.A056.07 |
| TCGA-E2-A15F | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.8 | LumA | European | TCGA.E2.A15F.01A.11R.A115.07 |
| TCGA-E2-A1IH | 80 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 1.8 | LumA | European | TCGA.E2.A1IH.01A.11R.A13Q.07 |
| TCGA-A2-A0YH | 53 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.8 | LumB | European | TCGA.A2.A0YH.01A.11R.A109.07 |
| TCGA-D8-A4Z1 | 68 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.8 | LumA | European | TCGA.D8.A4Z1.01A.21R.A266.07 |
| TCGA-E9-A1RE | 74 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 1.8 | LumB | European | TCGA.E9.A1RE.01A.11R.A157.07 |
| TCGA-BH-A0BJ | 41 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.81 | LumA | European | TCGA.BH.A0BJ.01A.11R.A056.07 |
| TCGA-BH-A0BJ | 41 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.81 | LumA | European | TCGA.BH.A0BJ.11A.23R.A089.07 |
| TCGA-A7-A26I | 65 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 1.81 | Basal | European | TCGA.A7.A26I.01A.11R.A169.07 |
| TCGA-BH-A8G0 | 54 | female | White | Primary solid Tumor | perimenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.81 | LumA | European | TCGA.BH.A8G0.01A.11R.A352.07 |
| TCGA-D8-A1XJ | 76 | female | White | Primary solid Tumor | postmenopausal | ductal/mucinous | positive | positive | positive | NA | NA | alive | 1.82 | NA | European | TCGA.D8.A1XJ.01A.11R.A14M.07 |
| TCGA-AQ-A54O | 51 | male | Black or African American | Primary solid Tumor | not applicable | IDC | positive | positive | negative | NA | NA | alive | 1.82 | NA | African | TCGA.AQ.A54O.01A.11R.A266.07 |
| TCGA-A2-A0YG | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.82 | LumB | European | TCGA.A2.A0YG.01A.21R.A109.07 |
| TCGA-A2-A4S3 | 59 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.82 | LumB | African_admix | TCGA.A2.A4S3.01A.21R.A266.07 |
| TCGA-A2-A04U | 47 | female | White | Primary solid Tumor | perimenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.84 | Basal | European | TCGA.A2.A04U.01A.11R.A115.07 |
| TCGA-AC-A3QP | 79 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 1.85 | LumA | European | TCGA.AC.A3QP.01A.11R.A22U.07 |
| TCGA-E2-A1IN | 60 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.85 | LumA | European | TCGA.E2.A1IN.01A.11R.A13Q.07 |
| TCGA-AC-A2B8 | 84 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | new primary | rectum | alive | 1.85 | LumA | European | TCGA.AC.A2B8.01A.11R.A17B.07 |
| TCGA-E2-A573 | 48 | female | Black or African American | Primary solid Tumor | perimenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 1.85 | Basal | African | TCGA.E2.A573.01A.11R.A29R.07 |
| TCGA-A7-A2KD | 53 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 1.86 | LumB | African | TCGA.A7.A2KD.01A.31R.A21T.07 |
| TCGA-OL-A5RZ | 57 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | not evaluated | NA | NA | alive | 1.86 | Her2 | African | TCGA.OL.A5RZ.01A.11R.A28M.07 |
| TCGA-AO-A0J8 | 61 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.86 | LumA | European | TCGA.AO.A0J8.01A.21R.A034.07 |
| TCGA-A2-A1FZ | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.87 | LumA | European | TCGA.A2.A1FZ.01A.51R.A14D.07 |
| TCGA-E2-A1IO | 37 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.88 | LumA | European | TCGA.E2.A1IO.01A.11R.A144.07 |
| TCGA-E2-A1IK | 71 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.89 | LumA | European | TCGA.E2.A1IK.01A.11R.A144.07 |
| TCGA-E9-A22B | 71 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | positive | negative | negative | NA | NA | alive | 1.89 | NA | European | TCGA.E9.A22B.01A.11R.A157.07 |
| TCGA-E2-A15C | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 1.9 | LumA | European | TCGA.E2.A15C.01A.31R.A12D.07 |
| TCGA-EW-A1OW | 58 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.9 | NA | African | TCGA.EW.A1OW.01A.21R.A144.07 |
| TCGA-BH-A0WA | 82 | female | White | Primary solid Tumor | not available | not available | negative | negative | negative | NA | NA | alive | 1.92 | NA | European | TCGA.BH.A0WA.01A.11R.A109.07 |
| TCGA-A8-A08B | 52 | female | not available | Primary solid Tumor | premenopausal | IDC | positive | negative | positive | NA | NA | alive | 1.92 | Her2 | European | TCGA.A8.A08B.01A.11R.A00Z.07 |
| TCGA-BH-A0H7 | 65 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.92 | LumA | European | TCGA.BH.A0H7.01A.13R.A056.07 |
| TCGA-BH-A0H7 | 65 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.92 | LumA | European | TCGA.BH.A0H7.11A.13R.A089.07 |
| TCGA-EW-A1P5 | 77 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.92 | LumA | European | TCGA.EW.A1P5.01A.11R.A144.07 |
| TCGA-A2-A4S0 | 77 | female | White | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | negative | NA | NA | alive | 1.93 | NA | European | TCGA.A2.A4S0.01A.21R.A266.07 |
| TCGA-AC-A3YI | 74 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 1.94 | Normal | European | TCGA.AC.A3YI.01A.21R.A239.07 |
| TCGA-E2-A153 | 51 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.94 | LumA | European | TCGA.E2.A153.01A.12R.A12D.07 |
| TCGA-E2-A153 | 51 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.94 | LumA | European | TCGA.E2.A153.11A.31R.A12D.07 |
| TCGA-E9-A1NC | 61 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | negative | positive | positive | NA | NA | alive | 1.94 | NA | European | TCGA.E9.A1NC.01A.21R.A26B.07 |
| TCGA-AR-A0TU | 35 | female | not available | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.94 | NA | European | TCGA.AR.A0TU.01A.31R.A109.07 |
| TCGA-E2-A15A | 45 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.94 | LumB | European | TCGA.E2.A15A.01A.11R.A12D.07 |
| TCGA-GI-A2C9 | 58 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.95 | NA | African | TCGA.GI.A2C9.01A.11R.A21T.07 |
| TCGA-GI-A2C9 | 58 | female | Black or African American | Solid Tissue Normal | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 1.95 | NA | African | TCGA.GI.A2C9.11A.22R.A21T.07 |
| TCGA-BH-A0DG | 30 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | negative | negative | NA | NA | alive | 1.95 | LumA | African | TCGA.BH.A0DG.01A.21R.A12P.07 |
| TCGA-BH-A0DG | 30 | female | Black or African American | Solid Tissue Normal | premenopausal | IDC | positive | negative | negative | NA | NA | alive | 1.95 | LumA | African | TCGA.BH.A0DG.11A.43R.A12P.07 |
| TCGA-E9-A22A | 74 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 1.95 | LumB | European | TCGA.E9.A22A.01A.11R.A157.07 |
| TCGA-A2-A1FV | 74 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.95 | LumA | European | TCGA.A2.A1FV.01A.11R.A13Q.07 |
| TCGA-OL-A66I | 36 | female | Black or African American | Primary solid Tumor | not evaluated | IDC | negative | negative | not evaluated | NA | NA | alive | 1.95 | Basal | African | TCGA.OL.A66I.01A.21R.A29R.07 |
| TCGA-BH-A5J0 | 63 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.96 | LumA | African | TCGA.BH.A5J0.01A.11R.A27Q.07 |
| TCGA-E9-A22G | 47 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 1.96 | Basal | European | TCGA.E9.A22G.01A.11R.A157.07 |
| TCGA-A7-A26G | 50 | female | Black or African American | Primary solid Tumor | premenopausal | IDC with Metaplastic features (area of sarcomatoid carcinoma) | negative | negative | negative | NA | NA | alive | 1.98 | NA | African | TCGA.A7.A26G.01A.21R.A169.07 |
| TCGA-A7-A26H | 72 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | equivocal | not available | NA | alive | 1.98 | LumA | European | TCGA.A7.A26H.01A.11R.A169.07 |
| TCGA-E9-A54Y | 63 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 1.98 | LumB | European | TCGA.E9.A54Y.01A.11R.A466.07 |
| TCGA-E2-A156 | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.99 | LumA | European | TCGA.E2.A156.01A.11R.A12D.07 |
| TCGA-BH-A0HF | 77 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 1.99 | NA | European | TCGA.BH.A0HF.01A.11R.A056.07 |
| TCGA-D8-A1X9 | 66 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | Indeterminate | NA | NA | alive | 1.99 | LumA | European | TCGA.D8.A1X9.01A.12R.A157.07 |
| TCGA-E9-A54X | 85 | female | White | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | negative | NA | NA | alive | 1.99 | NA | European | TCGA.E9.A54X.01A.11R.A266.07 |
| TCGA-BH-A0W3 | 58 | female | White | Primary solid Tumor | indeterminate | IDC | positive | positive | equivocal | NA | NA | alive | 1.99 | LumB | European | TCGA.BH.A0W3.01A.11R.A109.07 |
| TCGA-A2-A0EU | 79 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.01 | LumA | European | TCGA.A2.A0EU.01A.22R.A056.07 |
| TCGA-OL-A5RV | 43 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 2.01 | LumA | African | TCGA.OL.A5RV.01A.12R.A28M.07 |
| TCGA-AC-A3QQ | 54 | female | White | Primary solid Tumor | perimenopausal | ILC | positive | positive | positive | NA | NA | alive | 2.01 | LumA | European | TCGA.AC.A3QQ.01A.11R.A22K.07 |
| TCGA-A7-A26F | 55 | female | White | Primary solid Tumor | postmenopausal | \adenocarcinoma with squamous differentiation, metaplastic\"" | negative | negative | equivocal | NA | NA | alive | 2.02 | NA | European | TCGA.A7.A26F.01A.21R.A169.07 |
| TCGA-AR-A0TW | 50 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.02 | LumA | European | TCGA.AR.A0TW.01A.11R.A084.07 |
| TCGA-A2-A4RX | 67 | female | Black or African American | Primary solid Tumor | postmenopausal | metaplastic carcinoma | positive | positive | negative | NA | NA | alive | 2.03 | NA | African | TCGA.A2.A4RX.01A.11R.A266.07 |
| TCGA-BH-A0EI | 51 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.03 | LumA | European | TCGA.BH.A0EI.01A.11R.A115.07 |
| TCGA-GM-A3NY | 72 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 2.03 | NA | European | TCGA.GM.A3NY.01A.11R.A21T.07 |
| TCGA-BH-A0EB | 69 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.04 | LumA | European | TCGA.BH.A0EB.01A.11R.A034.07 |
| TCGA-BH-A0AU | 45 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 2.04 | LumB | European | TCGA.BH.A0AU.01A.11R.A12P.07 |
| TCGA-BH-A0AU | 45 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 2.04 | LumB | European | TCGA.BH.A0AU.11A.11R.A12P.07 |
| TCGA-BH-A0H6 | 82 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.05 | LumA | European | TCGA.BH.A0H6.01A.21R.A056.07 |
| TCGA-C8-A27A | 48 | female | Asian | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.05 | LumB | East Asian | TCGA.C8.A27A.01A.11R.A169.07 |
| TCGA-E9-A24A | 69 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 2.05 | LumA | European | TCGA.E9.A24A.01A.11R.A169.07 |
| TCGA-E2-A14V | 53 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 2.05 | Her2 | European | TCGA.E2.A14V.01A.11R.A12D.07 |
| TCGA-A2-A0EX | 46 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 2.06 | LumA | European | TCGA.A2.A0EX.01A.21R.A034.07 |
| TCGA-OL-A5RY | 52 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | not evaluated | NA | NA | alive | 2.06 | Normal | African | TCGA.OL.A5RY.01A.21R.A28M.07 |
| TCGA-AC-A3YJ | 66 | female | White | Primary solid Tumor | postmenopausal | invasive papillary carcinoma | positive | positive | not available | NA | NA | alive | 2.06 | NA | European | TCGA.AC.A3YJ.01A.11R.A22U.07 |
| TCGA-AQ-A04H | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | Indeterminate | NA | NA | alive | 2.06 | LumB | European | TCGA.AQ.A04H.01B.11R.A10J.07 |
| TCGA-E9-A1QZ | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 2.07 | LumA | European | TCGA.E9.A1QZ.01A.21R.A169.07 |
| TCGA-BH-A0BG | 73 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 2.07 | Basal | European | TCGA.BH.A0BG.01A.11R.A115.07 |
| TCGA-BH-A0W4 | 46 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | alive | 2.08 | LumA | European | TCGA.BH.A0W4.01A.11R.A109.07 |
| TCGA-LL-A440 | 61 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 2.08 | LumA | European | TCGA.LL.A440.01A.11R.A24H.07 |
| TCGA-A8-A07U | 66 | female | not available | Primary solid Tumor | postmenopausal | IDC | negative | positive | negative | NA | NA | alive | 2.08 | Basal | European | TCGA.A8.A07U.01A.11R.A034.07 |
| TCGA-EW-A6SB | 62 | female | Black or African American | Primary solid Tumor | not available | IDC | negative | negative | negative | NA | NA | alive | 2.08 | Basal | African | TCGA.EW.A6SB.01A.12R.A32P.07 |
| TCGA-A2-A0D2 | 45 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 2.08 | Basal | European | TCGA.A2.A0D2.01A.21R.A034.07 |
| TCGA-A8-A09Q | 83 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.08 | LumB | European | TCGA.A8.A09Q.01A.11R.A00Z.07 |
| TCGA-LL-A50Y | 84 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 2.09 | LumA | European | TCGA.LL.A50Y.01A.11R.A266.07 |
| TCGA-E2-A107 | 54 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | equivocal | NA | NA | alive | 2.09 | LumA | European | TCGA.E2.A107.01A.11R.A10J.07 |
| TCGA-A2-A04Y | 53 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.09 | LumB | European | TCGA.A2.A04Y.01A.21R.A034.07 |
| TCGA-A7-A13F | 44 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.09 | LumB | European | TCGA.A7.A13F.01A.11R.A12P.07 |
| TCGA-A7-A13F | 44 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.09 | LumB | European | TCGA.A7.A13F.11A.42R.A12P.07 |
| TCGA-A2-A0D4 | 37 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.1 | LumB | African_admix | TCGA.A2.A0D4.01A.11R.A00Z.07 |
| TCGA-D8-A73X | 53 | female | White | Primary solid Tumor | postmenopausal | tubular carcinoma | positive | positive | negative | NA | NA | alive | 2.1 | NA | European | TCGA.D8.A73X.01A.11R.A32P.07 |
| TCGA-A2-A0YD | 63 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | NA | NA | alive | 2.11 | LumA | European | TCGA.A2.A0YD.01A.11R.A109.07 |
| TCGA-E2-A150 | 48 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 2.12 | Basal | European | TCGA.E2.A150.01A.11R.A12D.07 |
| TCGA-AO-A0J6 | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 2.12 | Basal | European | TCGA.AO.A0J6.01A.11R.A034.07 |
| TCGA-BH-A0AY | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.13 | LumA | European | TCGA.BH.A0AY.01A.21R.A00Z.07 |
| TCGA-BH-A0AY | 62 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.13 | LumA | European | TCGA.BH.A0AY.11A.23R.A089.07 |
| TCGA-D8-A1X8 | 62 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | Indeterminate | negative | NA | NA | alive | 2.14 | LumA | European | TCGA.D8.A1X8.01A.11R.A14M.07 |
| TCGA-E9-A5UO | 41 | female | White | Primary solid Tumor | premenopausal | mucinous carcinoma | not evaluated | not evaluated | not evaluated | NA | NA | alive | 2.15 | NA | European | TCGA.E9.A5UO.01A.11R.A28M.07 |
| TCGA-A2-A0D1 | 76 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 2.15 | Her2 | European | TCGA.A2.A0D1.01A.11R.A034.07 |
| TCGA-EW-A2FV | 39 | female | White | Primary solid Tumor | premenopausal | invasive micropapillary ductal carcinoma | positive | positive | negative | NA | NA | alive | 2.16 | NA | European | TCGA.EW.A2FV.01A.11R.A17B.07 |
| TCGA-EW-A1OV | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 2.16 | Her2 | European | TCGA.EW.A1OV.01A.11R.A144.07 |
| TCGA-A8-A06Y | 66 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | not available | not available | alive | 2.17 | LumA | European | TCGA.A8.A06Y.01A.21R.A00Z.07 |
| TCGA-OL-A66N | 59 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | not evaluated | NA | NA | alive | 2.17 | LumA | European | TCGA.OL.A66N.01A.12R.A31O.07 |
| TCGA-E9-A3HO | 49 | female | White | Primary solid Tumor | premenopausal | ILC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 2.17 | LumB | European | TCGA.E9.A3HO.01A.11R.A213.07 |
| TCGA-BH-A202 | 60 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 2.18 | LumB | European | TCGA.BH.A202.01A.11R.A14M.07 |
| TCGA-OL-A5RW | 40 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | negative | negative | not evaluated | NA | NA | alive | 2.18 | Basal | African | TCGA.OL.A5RW.01A.11R.A28M.07 |
| TCGA-AO-A0JG | 49 | female | White | Primary solid Tumor | postmenopausal | ductal/mucinous | positive | positive | negative | NA | NA | alive | 2.18 | NA | European | TCGA.AO.A0JG.01A.31R.A084.07 |
| TCGA-E9-A5UP | 63 | female | White | Primary solid Tumor | postmenopausal | infiltrating papillary adenocarcinoma | not evaluated | not evaluated | not evaluated | NA | NA | alive | 2.2 | NA | European | TCGA.E9.A5UP.01A.11R.A28M.07 |
| TCGA-A2-A3KD | 47 | female | White | Primary solid Tumor | premenopausal | mucinous carcinoma | positive | positive | negative | NA | NA | alive | 2.2 | NA | European | TCGA.A2.A3KD.01A.12R.A213.07 |
| TCGA-BH-A0HB | 55 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.21 | LumA | European | TCGA.BH.A0HB.01A.11R.A056.07 |
| TCGA-A2-A0ET | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.21 | LumA | European | TCGA.A2.A0ET.01A.31R.A034.07 |
| TCGA-E2-A574 | 44 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 2.21 | Basal | African_admix | TCGA.E2.A574.01A.11R.A29R.07 |
| TCGA-E9-A5FK | 60 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 2.22 | LumA | European | TCGA.E9.A5FK.01A.11R.A27Q.07 |
| TCGA-OL-A66H | 74 | female | Black or African American | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | not evaluated | NA | NA | alive | 2.22 | NA | African_admix | TCGA.OL.A66H.01A.11R.A29R.07 |
| TCGA-AQ-A04J | 45 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 2.24 | Basal | European | TCGA.AQ.A04J.01A.02R.A034.07 |
| TCGA-A2-A4S1 | 66 | female | White | Primary solid Tumor | postmenopausal | metaplastic carcinoma | positive | negative | negative | NA | NA | alive | 2.25 | Basal | European | TCGA.A2.A4S1.01A.21R.A266.07 |
| TCGA-A8-A0A9 | 80 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.25 | LumA | European | TCGA.A8.A0A9.01A.11R.A00Z.07 |
| TCGA-E2-A152 | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | metastasis | liver>breast recur | alive | 2.26 | Her2 | European | TCGA.E2.A152.01A.11R.A12D.07 |
| TCGA-BH-A0BQ | 39 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | locoregional recurrence | dermis|epidermis | alive | 2.26 | LumA | European | TCGA.BH.A0BQ.01A.21R.A115.07 |
| TCGA-BH-A0BQ | 39 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | positive | locoregional recurrence | dermis|epidermis | alive | 2.26 | LumA | European | TCGA.BH.A0BQ.11A.33R.A115.07 |
| TCGA-E9-A247 | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 2.27 | LumA | European | TCGA.E9.A247.01A.11R.A169.07 |
| TCGA-BH-A0HX | 54 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.27 | LumA | European | TCGA.BH.A0HX.01A.21R.A056.07 |
| TCGA-E2-A572 | 72 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.28 | NA | African_admix | TCGA.E2.A572.01A.13R.A31O.07 |
| TCGA-E2-A14S | 65 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.28 | NA | European | TCGA.E2.A14S.01A.11R.A12D.07 |
| TCGA-E2-A1L7 | 40 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | new primary | contralateral | alive | 2.28 | LumB | European | TCGA.E2.A1L7.01A.11R.A144.07 |
| TCGA-E2-A1L7 | 40 | female | White | Solid Tissue Normal | premenopausal | IDC | negative | negative | negative | new primary | contralateral | alive | 2.28 | LumB | European | TCGA.E2.A1L7.11A.33R.A144.07 |
| TCGA-E2-A108 | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.29 | Normal | European | TCGA.E2.A108.01A.13R.A10J.07 |
| TCGA-E2-A14U | 74 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 2.29 | NA | European_admix | TCGA.E2.A14U.01A.11R.A22K.07 |
| TCGA-E9-A1ND | 75 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 2.29 | Basal | European | TCGA.E9.A1ND.01A.11R.A144.07 |
| TCGA-E9-A1ND | 75 | female | White | Solid Tissue Normal | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 2.29 | Basal | European | TCGA.E9.A1ND.11A.43R.A144.07 |
| TCGA-D8-A1XA | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.3 | LumA | European | TCGA.D8.A1XA.01A.11R.A14D.07 |
| TCGA-OL-A5RU | 63 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 2.3 | LumA | African | TCGA.OL.A5RU.01A.11R.A28M.07 |
| TCGA-AR-A2LR | 49 | female | White | Primary solid Tumor | postmenopausal | metaplastic carcinoma | negative | negative | negative | NA | NA | alive | 2.32 | NA | European | TCGA.AR.A2LR.01A.12R.A18M.07 |
| TCGA-OL-A6VR | 48 | female | Black or African American | Primary solid Tumor | unknown | IDC | positive | positive | negative | NA | NA | alive | 2.32 | LumA | African_admix | TCGA.OL.A6VR.01A.32R.A33J.07 |
| TCGA-LQ-A4E4 | 73 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | metastasis | bone | alive | 2.32 | NA | European | TCGA.LQ.A4E4.01A.11R.A266.07 |
| TCGA-E2-A1II | 51 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | positive | negative | NA | NA | alive | 2.33 | Basal | European | TCGA.E2.A1II.01A.11R.A144.07 |
| TCGA-A1-A0SO | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 2.33 | Basal | European | TCGA.A1.A0SO.01A.22R.A084.07 |
| TCGA-A8-A07Z | 85 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.34 | LumA | European | TCGA.A8.A07Z.01A.11R.A00Z.07 |
| TCGA-E2-A10C | 54 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.34 | LumB | European | TCGA.E2.A10C.01A.21R.A10J.07 |
| TCGA-BH-A0HA | 31 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | not available | NA | NA | alive | 2.34 | LumA | European | TCGA.BH.A0HA.01A.11R.A12P.07 |
| TCGA-BH-A0HA | 31 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | not available | NA | NA | alive | 2.34 | LumA | European | TCGA.BH.A0HA.11A.31R.A12P.07 |
| TCGA-BH-A201 | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.34 | LumA | European | TCGA.BH.A201.01A.11R.A14M.07 |
| TCGA-OL-A6VO | 43 | female | Black or African American | Primary solid Tumor | unknown | IDC | negative | negative | negative | NA | NA | alive | 2.35 | Basal | African_admix | TCGA.OL.A6VO.01A.12R.A33J.07 |
| TCGA-A2-A3Y0 | 57 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 2.35 | Basal | African | TCGA.A2.A3Y0.01A.11R.A239.07 |
| TCGA-E9-A1R0 | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 2.35 | LumA | European | TCGA.E9.A1R0.01A.22R.A16F.07 |
| TCGA-AO-A12H | 69 | female | Black or African American | Primary solid Tumor | premenopausal | mucinous/papillary | positive | positive | negative | NA | NA | alive | 2.36 | NA | African | TCGA.AO.A12H.01A.11R.A115.07 |
| TCGA-E2-A10E | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.37 | NA | European | TCGA.E2.A10E.01A.21R.A10J.07 |
| TCGA-E2-A1IJ | 57 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 2.37 | LumA | European | TCGA.E2.A1IJ.01A.11R.A144.07 |
| TCGA-BH-A0AZ | 47 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.37 | LumA | European | TCGA.BH.A0AZ.01A.21R.A12P.07 |
| TCGA-BH-A0AZ | 47 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.37 | LumA | European | TCGA.BH.A0AZ.11A.22R.A12P.07 |
| TCGA-E2-A1B6 | 44 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 2.37 | Basal | European | TCGA.E2.A1B6.01A.31R.A12P.07 |
| TCGA-BH-A0HY | 60 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | NA | NA | alive | 2.38 | LumB | European | TCGA.BH.A0HY.01A.11R.A056.07 |
| TCGA-E2-A14Y | 35 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.38 | Basal | European | TCGA.E2.A14Y.01A.21R.A12D.07 |
| TCGA-A2-A0D3 | 42 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.4 | LumA | European | TCGA.A2.A0D3.01A.11R.A115.07 |
| TCGA-EW-A1PG | 53 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 2.4 | Normal | European | TCGA.EW.A1PG.01A.11R.A144.07 |
| TCGA-E2-A10F | 47 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 2.4 | LumA | European | TCGA.E2.A10F.01A.11R.A10J.07 |
| TCGA-OL-A5RX | 51 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 2.4 | LumA | African | TCGA.OL.A5RX.01A.11R.A28M.07 |
| TCGA-A8-A08C | 65 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 2.41 | NA | European | TCGA.A8.A08C.01A.11R.A00Z.07 |
| TCGA-WT-AB44 | 77 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 2.42 | LumA | European | TCGA.WT.AB44.01A.11R.A41B.07 |
| TCGA-AO-A03V | 41 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.43 | LumA | European | TCGA.AO.A03V.01A.11R.A115.07 |
| TCGA-LL-A442 | 56 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.43 | NA | African | TCGA.LL.A442.01A.11R.A24H.07 |
| TCGA-AC-A4ZE | 63 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 2.44 | LumA | European | TCGA.AC.A4ZE.01A.11R.A41B.07 |
| TCGA-E2-A14T | 52 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.44 | LumA | European | TCGA.E2.A14T.01A.11R.A115.07 |
| TCGA-AR-A2LQ | 59 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 2.45 | Normal | European | TCGA.AR.A2LQ.01A.22R.A18M.07 |
| TCGA-AR-A0TV | 66 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.48 | LumB | European | TCGA.AR.A0TV.01A.21R.A084.07 |
| TCGA-EW-A1OY | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.49 | LumB | European | TCGA.EW.A1OY.01A.11R.A144.07 |
| TCGA-EW-A1OX | 43 | female | White | Primary solid Tumor | premenopausal | mucinous carcinoma | positive | positive | negative | NA | NA | alive | 2.49 | NA | African_admix | TCGA.EW.A1OX.01A.11R.A144.07 |
| TCGA-A8-A09K | 68 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.5 | NA | European | TCGA.A8.A09K.01A.11R.A00Z.07 |
| TCGA-BH-A0DI | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.5 | LumA | European | TCGA.BH.A0DI.01A.21R.A12P.07 |
| TCGA-E9-A22E | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 2.5 | LumB | European | TCGA.E9.A22E.01A.11R.A157.07 |
| TCGA-E9-A3QA | 33 | female | White | Primary solid Tumor | premenopausal | medullary carcinoma | not evaluated | not evaluated | not evaluated | NA | NA | alive | 2.51 | Basal | European | TCGA.E9.A3QA.01A.61R.A22K.07 |
| TCGA-EW-A1P1 | 68 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | metastasis | lung | alive | 2.52 | Normal | European | TCGA.EW.A1P1.01A.31R.A14D.07 |
| TCGA-BH-A0GY | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.53 | LumA | European | TCGA.BH.A0GY.01A.11R.A056.07 |
| TCGA-E9-A3X8 | 48 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | alive | 2.54 | LumA | European | TCGA.E9.A3X8.01A.31R.A22U.07 |
| TCGA-A7-A0CJ | 57 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.55 | LumB | European | TCGA.A7.A0CJ.01A.21R.A00Z.07 |
| TCGA-E2-A570 | 47 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 2.55 | LumA | African | TCGA.E2.A570.01A.11R.A29R.07 |
| TCGA-A2-A1FX | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 2.56 | LumB | European | TCGA.A2.A1FX.01A.11R.A13Q.07 |
| TCGA-AR-A2LO | 46 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 2.56 | LumA | European | TCGA.AR.A2LO.01A.31R.A18M.07 |
| TCGA-EW-A1OZ | 56 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | negative | equivocal | NA | NA | alive | 2.58 | LumB | African | TCGA.EW.A1OZ.01A.11R.A144.07 |
| TCGA-A8-A092 | 48 | female | not available | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.58 | LumB | European | TCGA.A8.A092.01A.11R.A00Z.07 |
| TCGA-A8-A08O | 45 | female | not available | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | not available | not available | alive | 2.58 | LumA | European | TCGA.A8.A08O.01A.21R.A056.07 |
| TCGA-A8-A08P | 70 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 2.58 | LumB | European | TCGA.A8.A08P.01A.11R.A00Z.07 |
| TCGA-A8-A09E | 73 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 2.58 | NA | European | TCGA.A8.A09E.01A.11R.A00Z.07 |
| TCGA-BH-A0EE | 68 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 2.58 | Her2 | European | TCGA.BH.A0EE.01A.11R.A034.07 |
| TCGA-OL-A66L | 71 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 2.59 | LumA | African | TCGA.OL.A66L.01A.12R.A31O.07 |
| TCGA-BH-A0DE | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.6 | LumA | European | TCGA.BH.A0DE.01A.11R.A115.07 |
| TCGA-EW-A6SC | 60 | female | Black or African American | Primary solid Tumor | not available | ILC | positive | positive | negative | NA | NA | alive | 2.61 | LumA | African | TCGA.EW.A6SC.01A.12R.A32P.07 |
| TCGA-A7-A26E | 71 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 2.61 | LumA | European | TCGA.A7.A26E.01A.11R.A169.07 |
| TCGA-E2-A1IF | 74 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.62 | LumA | European | TCGA.E2.A1IF.01A.11R.A144.07 |
| TCGA-A2-A0YM | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | not evaluated | NA | NA | alive | 2.64 | Basal | European | TCGA.A2.A0YM.01A.11R.A109.07 |
| TCGA-A7-A13D | 46 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | positive | equivocal | NA | NA | alive | 2.64 | Basal | African | TCGA.A7.A13D.01A.13R.A12P.07 |
| TCGA-A2-A0EV | 80 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.65 | LumA | European | TCGA.A2.A0EV.01A.11R.A034.07 |
| TCGA-E2-A14X | 55 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 2.66 | Basal | African_admix | TCGA.E2.A14X.01A.11R.A115.07 |
| TCGA-E2-A1LB | 41 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | negative | negative | positive | NA | NA | alive | 2.66 | Her2 | African | TCGA.E2.A1LB.01A.11R.A144.07 |
| TCGA-E2-A1LB | 41 | female | Black or African American | Solid Tissue Normal | premenopausal | IDC | negative | negative | positive | NA | NA | alive | 2.66 | Her2 | African | TCGA.E2.A1LB.11A.22R.A144.07 |
| TCGA-A2-A3XZ | 46 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | negative | negative | positive | NA | NA | alive | 2.66 | Her2 | African | TCGA.A2.A3XZ.01A.42R.A239.07 |
| TCGA-OL-A5D8 | 40 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 2.66 | LumA | African | TCGA.OL.A5D8.01A.11R.A27Q.07 |
| TCGA-BH-A0BC | 60 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.67 | LumA | European | TCGA.BH.A0BC.01A.22R.A084.07 |
| TCGA-BH-A0BC | 60 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.67 | LumA | European | TCGA.BH.A0BC.11A.22R.A089.07 |
| TCGA-E2-A14Q | 50 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.67 | LumA | European | TCGA.E2.A14Q.01A.11R.A12D.07 |
| TCGA-E2-A14W | 78 | male | White | Primary solid Tumor | not applicable | IDC | positive | positive | not evaluated | NA | NA | alive | 2.67 | NA | European | TCGA.E2.A14W.01A.11R.A12D.07 |
| TCGA-A8-A07L | 58 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.67 | LumB | European | TCGA.A8.A07L.01A.11R.A00Z.07 |
| TCGA-E9-A1RA | 48 | female | White | Primary solid Tumor | premenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 2.67 | LumA | European | TCGA.E9.A1RA.01A.11R.A14D.07 |
| TCGA-GM-A3XG | 46 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 2.69 | NA | European | TCGA.GM.A3XG.01A.31R.A24H.07 |
| TCGA-E2-A1IE | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | metastasis | liver | alive | 2.69 | LumA | European | TCGA.E2.A1IE.01A.11R.A13Q.07 |
| TCGA-E2-A1B5 | 46 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 2.69 | LumA | European | TCGA.E2.A1B5.01A.21R.A12P.07 |
| TCGA-AC-A3BB | 46 | female | Black or African American | Primary solid Tumor | not available | ILC | positive | positive | negative | NA | NA | alive | 2.7 | NA | African | TCGA.AC.A3BB.01A.21R.A19W.07 |
| TCGA-EW-A1P3 | 48 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.7 | LumA | European | TCGA.EW.A1P3.01A.11R.A144.07 |
| TCGA-AQ-A1H3 | 49 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.71 | LumA | European | TCGA.AQ.A1H3.01A.31R.A13Q.07 |
| TCGA-A2-A0YC | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | metastasis | bone | alive | 2.71 | LumA | European | TCGA.A2.A0YC.01A.11R.A109.07 |
| TCGA-AR-A24W | 55 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.71 | LumA | European | TCGA.AR.A24W.01A.11R.A169.07 |
| TCGA-A2-A3XV | 46 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | negative | equivocal | NA | NA | alive | 2.73 | Her2 | African_admix | TCGA.A2.A3XV.01A.21R.A239.07 |
| TCGA-LL-A441 | 62 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 2.73 | NA | African | TCGA.LL.A441.01A.11R.A24H.07 |
| TCGA-AO-A0J2 | 41 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 2.73 | Her2 | European | TCGA.AO.A0J2.01A.11R.A034.07 |
| TCGA-AR-A2LN | 65 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 2.73 | LumA | European | TCGA.AR.A2LN.01A.21R.A18M.07 |
| TCGA-E2-A1IG | 45 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.73 | LumA | European | TCGA.E2.A1IG.01A.11R.A144.07 |
| TCGA-E2-A1IG | 45 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 2.73 | LumA | European | TCGA.E2.A1IG.11A.22R.A144.07 |
| TCGA-EW-A6SD | 32 | female | Black or African American | Primary solid Tumor | not available | IDC | negative | negative | not evaluated | NA | NA | alive | 2.77 | Her2 | African | TCGA.EW.A6SD.01A.12R.A33J.07 |
| TCGA-BH-A0HQ | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 3.07 | LumA | European | TCGA.BH.A0HQ.01A.11R.A034.07 |
| TCGA-A8-A085 | 44 | male | not available | Primary solid Tumor | not applicable | IDC | positive | positive | negative | NA | NA | alive | 3.08 | NA | European | TCGA.A8.A085.01A.11R.A00Z.07 |
| TCGA-BH-A0BA | 51 | female | White | Primary solid Tumor | premenopausal | IDC/ILC | positive | positive | negative | NA | NA | alive | 3.1 | NA | European | TCGA.BH.A0BA.01A.11R.A056.07 |
| TCGA-BH-A0BA | 51 | female | White | Solid Tissue Normal | premenopausal | IDC/ILC | positive | positive | negative | NA | NA | alive | 3.1 | NA | European | TCGA.BH.A0BA.11A.22R.A19E.07 |
| TCGA-BH-A0B1 | 66 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 3.14 | NA | European | TCGA.BH.A0B1.01A.12R.A056.07 |
| TCGA-AR-A1AS | 54 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 3.15 | LumA | South Asian | TCGA.AR.A1AS.01A.11R.A12P.07 |
| TCGA-BH-A0DH | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 3.16 | LumA | European | TCGA.BH.A0DH.01A.11R.A084.07 |
| TCGA-BH-A0DH | 63 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 3.16 | LumA | European | TCGA.BH.A0DH.11A.31R.A089.07 |
| TCGA-A8-A0AD | 83 | female | not available | Primary solid Tumor | postmenopausal | IDC/ILC | positive | positive | negative | NA | NA | alive | 3.17 | NA | European | TCGA.A8.A0AD.01A.11R.A056.07 |
| TCGA-BH-A0B4 | 65 | male | White | Primary solid Tumor | not applicable | IDC | positive | positive | equivocal | NA | NA | alive | 3.26 | NA | European | TCGA.BH.A0B4.01A.11R.A00Z.07 |
| TCGA-A1-A0SN | 50 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 3.27 | LumB | European | TCGA.A1.A0SN.01A.11R.A144.07 |
| TCGA-BH-A0B3 | 53 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 3.29 | Basal | European | TCGA.BH.A0B3.01A.11R.A056.07 |
| TCGA-BH-A0B3 | 53 | female | White | Solid Tissue Normal | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 3.29 | Basal | European | TCGA.BH.A0B3.11B.21R.A089.07 |
| TCGA-EW-A1IX | 48 | female | Asian | Primary solid Tumor | perimenopausal | invasive tubulolobular carcinoma | positive | positive | negative | NA | NA | alive | 3.31 | NA | East Asian | TCGA.EW.A1IX.01A.12R.A144.07 |
| TCGA-A8-A08Z | 76 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 3.33 | LumA | European | TCGA.A8.A08Z.01A.21R.A00Z.07 |
| TCGA-E9-A1RC | 56 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 3.35 | NA | European | TCGA.E9.A1RC.01A.11R.A157.07 |
| TCGA-E9-A1RC | 56 | female | White | Solid Tissue Normal | postmenopausal | IDC/ILC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 3.35 | NA | European | TCGA.E9.A1RC.11A.33R.A157.07 |
| TCGA-BH-A0H9 | 69 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 3.41 | LumA | European | TCGA.BH.A0H9.01A.11R.A056.07 |
| TCGA-BH-A0H9 | 69 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 3.41 | LumA | European | TCGA.BH.A0H9.11A.22R.A466.07 |
| TCGA-EW-A1P0 | 55 | female | White | Primary solid Tumor | postmenopausal | IDC/mucinous | positive | negative | negative | metastasis | mediastinal lymph node | alive | 3.43 | NA | European | TCGA.EW.A1P0.01A.11R.A144.07 |
| TCGA-BH-A0C0 | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 3.48 | LumB | European | TCGA.BH.A0C0.01A.21R.A056.07 |
| TCGA-BH-A0C0 | 62 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 3.48 | LumB | European | TCGA.BH.A0C0.11A.21R.A089.07 |
| TCGA-A8-A095 | 45 | female | not available | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 3.5 | LumB | European | TCGA.A8.A095.01A.11R.A00Z.07 |
| TCGA-A8-A07B | 69 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 3.58 | LumA | European | TCGA.A8.A07B.01A.11R.A00Z.07 |
| TCGA-A8-A08X | 43 | female | not available | Primary solid Tumor | premenopausal | IDC | negative | negative | positive | not available | not available | alive | 3.58 | Her2 | European | TCGA.A8.A08X.01A.21R.A00Z.07 |
| TCGA-E2-A105 | 79 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 3.58 | LumA | European | TCGA.E2.A105.01A.11R.A10J.07 |
| TCGA-E2-A1LL | 73 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | metastasis | liver | alive | 3.58 | Basal | African_admix | TCGA.E2.A1LL.01A.11R.A144.07 |
| TCGA-A1-A0SE | 56 | female | White | Primary solid Tumor | premenopausal | IDC/ILC | positive | positive | negative | NA | NA | alive | 3.62 | NA | European | TCGA.A1.A0SE.01A.11R.A084.07 |
| TCGA-B6-A1KC | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 3.63 | LumB | European | TCGA.B6.A1KC.01B.11R.A157.07 |
| TCGA-A2-A0SY | 62 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | NA | NA | alive | 3.69 | LumA | European | TCGA.A2.A0SY.01A.31R.A084.07 |
| TCGA-E2-A14O | 76 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 3.72 | LumB | European | TCGA.E2.A14O.01A.31R.A115.07 |
| TCGA-BH-A0E7 | 79 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 3.73 | LumA | European | TCGA.BH.A0E7.01A.11R.A034.07 |
| TCGA-A8-A09I | 84 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 3.75 | LumB | European | TCGA.A8.A09I.01A.22R.A034.07 |
| TCGA-E2-A109 | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | equivocal | NA | NA | alive | 3.88 | LumB | European | TCGA.E2.A109.01A.11R.A10J.07 |
| TCGA-E2-A14N | 37 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 3.93 | Basal | European | TCGA.E2.A14N.01A.31R.A137.07 |
| TCGA-A1-A0SH | 39 | female | White | Primary solid Tumor | premenopausal | IDC | negative | positive | equivocal | NA | NA | alive | 3.93 | LumA | European | TCGA.A1.A0SH.01A.11R.A084.07 |
| TCGA-3C-AALK | 52 | female | Black or African American | Primary solid Tumor | unknown | IDC | positive | positive | positive | NA | NA | alive | 3.96 | LumA | African | TCGA.3C.AALK.01A.11R.A41B.07 |
| TCGA-A1-A0SF | 54 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 4.01 | LumA | European | TCGA.A1.A0SF.01A.11R.A144.07 |
| TCGA-5L-AAT1 | 63 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | metastasis | bone | alive | 4.03 | NA | European | TCGA.5L.AAT1.01A.12R.A41B.07 |
| TCGA-3C-AALJ | 62 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | Indeterminate | NA | NA | alive | 4.04 | LumB | African_admix | TCGA.3C.AALJ.01A.31R.A41B.07 |
| TCGA-C8-A12Y | 44 | female | Asian | Primary solid Tumor | premenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 4.04 | LumA | East Asian | TCGA.C8.A12Y.01A.11R.A12D.07 |
| TCGA-BH-A0BV | 78 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 4.16 | LumA | European | TCGA.BH.A0BV.01A.11R.A00Z.07 |
| TCGA-BH-A0BV | 78 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 4.16 | LumA | European | TCGA.BH.A0BV.11A.31R.A089.07 |
| TCGA-AO-A0JI | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 4.18 | LumA | European | TCGA.AO.A0JI.01A.21R.A056.07 |
| TCGA-A2-A0SX | 48 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 4.2 | Basal | European | TCGA.A2.A0SX.01A.12R.A084.07 |
| TCGA-AO-A0JB | 50 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 4.22 | Normal | European | TCGA.AO.A0JB.01A.11R.A32Y.07 |
| TCGA-AO-A0JC | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 4.24 | LumA | European | TCGA.AO.A0JC.01A.11R.A056.07 |
| TCGA-AR-A24K | 46 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 4.24 | LumB | European | TCGA.AR.A24K.01A.11R.A169.07 |
| TCGA-BH-A0HW | 62 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | negative | equivocal | NA | NA | alive | 4.27 | LumB | East Asian | TCGA.BH.A0HW.01A.11R.A034.07 |
| TCGA-BH-A0B8 | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 4.3 | NA | European | TCGA.BH.A0B8.01A.21R.A056.07 |
| TCGA-BH-A0B8 | 64 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 4.3 | NA | European | TCGA.BH.A0B8.11A.41R.A089.07 |
| TCGA-BH-A0B9 | 44 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 4.3 | Basal | European | TCGA.BH.A0B9.01A.11R.A056.07 |
| TCGA-A2-A259 | 70 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 4.37 | LumA | African_admix | TCGA.A2.A259.01A.11R.A16F.07 |
| TCGA-EW-A2FS | 41 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | negative | negative | NA | NA | alive | 4.39 | LumA | African | TCGA.EW.A2FS.01A.11R.A17B.07 |
| TCGA-WT-AB41 | 55 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 4.41 | LumA | African | TCGA.WT.AB41.01A.11R.A41B.07 |
| TCGA-AO-A0J9 | 61 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | metastasis | bone | alive | 4.42 | LumA | European | TCGA.AO.A0J9.01A.11R.A034.07 |
| TCGA-A8-A06T | 75 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 4.42 | LumA | European | TCGA.A8.A06T.01A.11R.A00Z.07 |
| TCGA-A2-A0CZ | 46 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 4.42 | NA | European | TCGA.A2.A0CZ.01A.11R.A034.07 |
| TCGA-BH-A0H5 | 45 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not available | NA | NA | alive | 4.44 | LumA | European | TCGA.BH.A0H5.01A.21R.A115.07 |
| TCGA-BH-A0H5 | 45 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | not available | NA | NA | alive | 4.44 | LumA | European | TCGA.BH.A0H5.11A.62R.A115.07 |
| TCGA-E2-A1B0 | 50 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 4.47 | Her2 | European | TCGA.E2.A1B0.01A.11R.A12P.07 |
| TCGA-AO-A12G | 75 | female | White | Primary solid Tumor | postmenopausal | pleomorphic ILC | positive | positive | positive | NA | NA | alive | 4.49 | NA | European | TCGA.AO.A12G.01A.11R.A10J.07 |
| TCGA-A8-A076 | 66 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 4.5 | LumB | European | TCGA.A8.A076.01A.21R.A00Z.07 |
| TCGA-E2-A1L6 | 44 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 4.51 | LumA | European | TCGA.E2.A1L6.01A.11R.A13Q.07 |
| TCGA-A2-A0SU | 66 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 4.55 | LumA | European | TCGA.A2.A0SU.01A.11R.A084.07 |
| TCGA-A2-A0CY | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 4.58 | NA | European | TCGA.A2.A0CY.01A.12R.A034.07 |
| TCGA-EW-A2FR | 59 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 4.58 | Her2 | South Asian | TCGA.EW.A2FR.01A.11R.A21T.07 |
| TCGA-AO-A0JL | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 4.61 | NA | European | TCGA.AO.A0JL.01A.11R.A056.07 |
| TCGA-A2-A04X | 34 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 4.62 | Her2 | European | TCGA.A2.A04X.01A.21R.A034.07 |
| TCGA-A2-A3XW | 42 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | negative | negative | NA | NA | alive | 4.69 | Normal | African_admix | TCGA.A2.A3XW.01A.11R.A239.07 |
| TCGA-A2-A0CX | 52 | female | White | Primary solid Tumor | premenopausal | IDC | positive | negative | positive | NA | NA | alive | 4.73 | Her2 | European | TCGA.A2.A0CX.01A.21R.A00Z.07 |
| TCGA-OL-A5D7 | 70 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | not evaluated | NA | NA | alive | 4.87 | Basal | African_admix | TCGA.OL.A5D7.01A.11R.A27Q.07 |
| TCGA-OL-A5DA | 61 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | NA | NA | alive | 4.88 | LumA | European | TCGA.OL.A5DA.01A.11R.A27Q.07 |
| TCGA-BH-A0AV | 52 | female | Black or African American | Primary solid Tumor | not available | IDC | negative | negative | not available | NA | NA | alive | 4.98 | Basal | African_admix | TCGA.BH.A0AV.01A.31R.A115.07 |
| TCGA-AO-A12F | 36 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 5.04 | Basal | European | TCGA.AO.A12F.01A.11R.A115.07 |
| TCGA-AC-A2FG | 79 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | not evaluated | NA | NA | alive | 5.07 | LumA | European | TCGA.AC.A2FG.01A.11R.A17B.07 |
| TCGA-AR-A1AV | 68 | male | White | Primary solid Tumor | not applicable | IDC | positive | positive | negative | NA | NA | alive | 5.1 | NA | European | TCGA.AR.A1AV.01A.21R.A12P.07 |
| TCGA-AO-A03M | 29 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 5.11 | LumA | European | TCGA.AO.A03M.01B.11R.A10J.07 |
| TCGA-BH-A0BM | 54 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 5.14 | LumA | European | TCGA.BH.A0BM.01A.11R.A056.07 |
| TCGA-BH-A0BM | 54 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 5.14 | LumA | European | TCGA.BH.A0BM.11A.12R.A089.07 |
| TCGA-AO-A1KQ | 84 | male | White | Primary solid Tumor | not applicable | IDC | positive | positive | negative | NA | NA | alive | 5.15 | NA | European | TCGA.AO.A1KQ.01A.11R.A13Q.07 |
| TCGA-AO-A0JJ | 54 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 5.17 | LumA | European | TCGA.AO.A0JJ.01A.11R.A056.07 |
| TCGA-BH-A0H3 | 46 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | not available | NA | NA | alive | 5.28 | LumA | European | TCGA.BH.A0H3.01A.11R.A12P.07 |
| TCGA-AR-A2LM | 49 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | not evaluated | NA | NA | alive | 5.3 | LumA | European | TCGA.AR.A2LM.01A.11R.A180.07 |
| TCGA-PE-A5DD | 64 | female | Asian | Primary solid Tumor | postmenopausal | ILC | positive | negative | positive | NA | NA | alive | 5.35 | LumA | East Asian_admix | TCGA.PE.A5DD.01A.12R.A27Q.07 |
| TCGA-AR-A0TX | 64 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 5.4 | Her2 | European | TCGA.AR.A0TX.01A.11R.A084.07 |
| TCGA-OL-A66J | 80 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | NA | NA | alive | 5.46 | LumA | European | TCGA.OL.A66J.01A.11R.A29R.07 |
| TCGA-GM-A3XN | 44 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 5.53 | NA | European | TCGA.GM.A3XN.01A.12R.A22U.07 |
| TCGA-AO-A03N | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | locoregional disease | NA | alive | 5.56 | LumB | European | TCGA.AO.A03N.01B.11R.A10J.07 |
| TCGA-V7-A7HQ | 75 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 5.57 | LumA | African_admix | TCGA.V7.A7HQ.01A.11R.A33J.07 |
| TCGA-BH-A0DV | 54 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 5.65 | LumA | European | TCGA.BH.A0DV.01A.21R.A12P.07 |
| TCGA-BH-A0DV | 54 | female | White | Solid Tissue Normal | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 5.65 | LumA | European | TCGA.BH.A0DV.11A.22R.A12P.07 |
| TCGA-B6-A408 | 55 | female | Black or African American | Primary solid Tumor | unknown | IDC/ILC | positive | positive | equivocal | NA | NA | alive | 5.67 | NA | African | TCGA.B6.A408.01A.12R.A24H.07 |
| TCGA-B6-A0RG | 26 | female | White | Primary solid Tumor | indeterminate | IDC | negative | negative | not evaluated | NA | NA | alive | 5.7 | LumA | European | TCGA.B6.A0RG.01A.11R.A056.07 |
| TCGA-AO-A03R | 57 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 5.72 | Normal | European | TCGA.AO.A03R.01A.21R.A034.07 |
| TCGA-GM-A3XL | 49 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | not evaluated | NA | NA | alive | 5.77 | Basal | African | TCGA.GM.A3XL.01A.11R.A22U.07 |
| TCGA-AO-A03T | 42 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 5.82 | Normal | European | TCGA.AO.A03T.01A.21R.A034.07 |
| TCGA-BH-A0B5 | 40 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 5.85 | LumA | European | TCGA.BH.A0B5.01A.11R.A12P.07 |
| TCGA-BH-A0B5 | 40 | female | White | Solid Tissue Normal | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 5.85 | LumA | European | TCGA.BH.A0B5.11A.23R.A12P.07 |
| TCGA-AO-A12E | 51 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 5.86 | LumA | European | TCGA.AO.A12E.01A.11R.A10J.07 |
| TCGA-GM-A2DF | 53 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 5.9 | Basal | African | TCGA.GM.A2DF.01A.11R.A180.07 |
| TCGA-BH-A0DX | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 5.9 | LumA | European | TCGA.BH.A0DX.01A.11R.A115.07 |
| TCGA-AR-A255 | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 5.92 | LumA | European | TCGA.AR.A255.01A.11R.A169.07 |
| TCGA-B6-A40C | 51 | female | White | Primary solid Tumor | unknown | ILC | positive | positive | negative | NA | NA | alive | 5.92 | LumA | European | TCGA.B6.A40C.01A.11R.A239.07 |
| TCGA-A2-A0ES | 52 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 6.0 | LumA | European | TCGA.A2.A0ES.01A.11R.A115.07 |
| TCGA-AO-A0JD | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 6.0 | LumB | European | TCGA.AO.A0JD.01A.11R.A056.07 |
| TCGA-GM-A4E0 | 67 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | NA | NA | alive | 6.0 | LumA | European | TCGA.GM.A4E0.01A.12R.A266.07 |
| TCGA-GM-A2DH | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 6.0 | Her2 | European | TCGA.GM.A2DH.01A.11R.A180.07 |
| TCGA-BH-A0BO | 54 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 6.02 | LumA | European | TCGA.BH.A0BO.01A.23R.A12D.07 |
| TCGA-AC-A2BK | 78 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 6.08 | Basal | African | TCGA.AC.A2BK.01A.11R.A21T.07 |
| TCGA-B6-A1KI | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 6.12 | LumA | European | TCGA.B6.A1KI.01A.11R.A14M.07 |
| TCGA-E2-A1L8 | 52 | female | Black or African American | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 6.13 | LumA | African | TCGA.E2.A1L8.01A.11R.A13Q.07 |
| TCGA-A2-A04T | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 6.15 | Basal | European | TCGA.A2.A04T.01A.21R.A034.07 |
| TCGA-AC-A2FO | 65 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | negative | NA | NA | alive | 6.17 | LumA | European | TCGA.AC.A2FO.01A.11R.A180.07 |
| TCGA-BH-A0BZ | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 6.17 | LumB | European | TCGA.BH.A0BZ.01A.31R.A12P.07 |
| TCGA-BH-A0BZ | 59 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 6.17 | LumB | European | TCGA.BH.A0BZ.11A.61R.A12P.07 |
| TCGA-A2-A0ER | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 6.2 | LumA | European | TCGA.A2.A0ER.01A.21R.A034.07 |
| TCGA-BH-A0BL | 35 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 6.24 | Basal | European | TCGA.BH.A0BL.01A.11R.A115.07 |
| TCGA-B6-A402 | 47 | female | Black or African American | Primary solid Tumor | unknown | IDC | negative | negative | negative | locoregional recurrence | breast>lymph node | alive | 6.25 | NA | African | TCGA.B6.A402.01A.11R.A239.07 |
| TCGA-GM-A2DD | 53 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 6.25 | Normal | European | TCGA.GM.A2DD.01A.11R.A180.07 |
| TCGA-A2-A0CT | 71 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | equivocal | NA | NA | alive | 6.27 | LumA | European | TCGA.A2.A0CT.01A.31R.A056.07 |
| TCGA-E2-A1AZ | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | Indeterminate | NA | NA | alive | 6.38 | Basal | American | TCGA.E2.A1AZ.01A.11R.A12P.07 |
| TCGA-BH-A0BR | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 6.38 | LumA | European | TCGA.BH.A0BR.01A.21R.A115.07 |
| TCGA-AO-A0JE | 53 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 6.39 | Her2 | African | TCGA.AO.A0JE.01A.11R.A056.07 |
| TCGA-BH-A0BT | 56 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | alive | 6.48 | LumA | European | TCGA.BH.A0BT.01A.11R.A12P.07 |
| TCGA-BH-A0BT | 56 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | negative | NA | NA | alive | 6.48 | LumA | European | TCGA.BH.A0BT.11A.21R.A12P.07 |
| TCGA-AO-A12C | 42 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 6.49 | NA | European | TCGA.AO.A12C.01A.11R.A10J.07 |
| TCGA-BH-A0DL | 64 | female | White | Primary solid Tumor | postmenopausal | IDC with metaplastic carcinoma and focal apocrine features | positive | negative | negative | NA | NA | alive | 6.52 | NA | European | TCGA.BH.A0DL.01A.11R.A115.07 |
| TCGA-BH-A0DL | 64 | female | White | Solid Tissue Normal | postmenopausal | IDC with metaplastic carcinoma and focal apocrine features | positive | negative | negative | NA | NA | alive | 6.52 | NA | European | TCGA.BH.A0DL.11A.13R.A115.07 |
| TCGA-AR-A1AJ | 83 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 6.52 | Basal | European | TCGA.AR.A1AJ.01A.21R.A12P.07 |
| TCGA-A2-A04Q | 48 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 6.53 | Basal | European | TCGA.A2.A04Q.01A.21R.A034.07 |
| TCGA-BH-A0DT | 41 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 6.58 | LumA | European | TCGA.BH.A0DT.01A.21R.A12D.07 |
| TCGA-BH-A0DT | 41 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 6.58 | LumA | European | TCGA.BH.A0DT.11A.12R.A12D.07 |
| TCGA-GM-A2DB | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 6.59 | Her2 | European | TCGA.GM.A2DB.01A.31R.A18M.07 |
| TCGA-A2-A0EQ | 64 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | alive | 6.64 | Her2 | African | TCGA.A2.A0EQ.01A.11R.A034.07 |
| TCGA-A2-A0EO | 54 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 6.69 | LumA | European | TCGA.A2.A0EO.01A.11R.A034.07 |
| TCGA-AO-A03L | 34 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 6.69 | LumA | South Asian_admix | TCGA.AO.A03L.01A.41R.A056.07 |
| TCGA-BH-A0B0 | 56 | female | Black or African American | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 6.78 | LumA | African_admix | TCGA.BH.A0B0.01A.21R.A115.07 |
| TCGA-BH-A0B6 | 47 | female | White | Primary solid Tumor | not available | IDC | positive | positive | positive | NA | NA | alive | 6.8 | NA | European | TCGA.BH.A0B6.01A.11R.A19W.07 |
| TCGA-BH-A0DD | 58 | male | White | Primary solid Tumor | not applicable | IDC | positive | positive | positive | NA | NA | alive | 6.81 | NA | European | TCGA.BH.A0DD.01A.31R.A12P.07 |
| TCGA-BH-A0DD | 58 | male | White | Solid Tissue Normal | not applicable | IDC | positive | positive | positive | NA | NA | alive | 6.81 | NA | European | TCGA.BH.A0DD.11A.23R.A12P.07 |
| TCGA-BH-A0E9 | 53 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 6.81 | LumA | European | TCGA.BH.A0E9.01B.11R.A115.07 |
| TCGA-AO-A1KR | 51 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 6.88 | Basal | European | TCGA.AO.A1KR.01A.12R.A144.07 |
| TCGA-AO-A12D | 43 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | positive | NA | NA | alive | 6.89 | Her2 | European | TCGA.AO.A12D.01A.11R.A115.07 |
| TCGA-GM-A2DC | 57 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 6.94 | LumA | European | TCGA.GM.A2DC.01A.11R.A18M.07 |
| TCGA-E2-A106 | 34 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 6.96 | NA | East Asian | TCGA.E2.A106.01A.11R.A10J.07 |
| TCGA-AR-A0TS | 46 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 7.0 | Basal | European | TCGA.AR.A0TS.01A.11R.A115.07 |
| TCGA-BH-A0B7 | 42 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 7.01 | Her2 | European | TCGA.BH.A0B7.01A.12R.A115.07 |
| TCGA-BH-A0B7 | 42 | female | White | Solid Tissue Normal | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 7.01 | Her2 | European | TCGA.BH.A0B7.11A.34R.A115.07 |
| TCGA-GM-A2DI | 52 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | not evaluated | NA | NA | alive | 7.09 | LumA | European | TCGA.GM.A2DI.01A.31R.A18M.07 |
| TCGA-B6-A401 | 47 | female | Black or African American | Primary solid Tumor | unknown | IDC | positive | positive | negative | NA | NA | alive | 7.11 | LumA | African_admix | TCGA.B6.A401.01A.11R.A239.07 |
| TCGA-GM-A2DO | 54 | female | Black or African American | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 7.11 | LumB | African | TCGA.GM.A2DO.01A.11R.A18M.07 |
| TCGA-AR-A254 | 50 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | positive | NA | NA | alive | 7.13 | Her2 | European | TCGA.AR.A254.01A.21R.A169.07 |
| TCGA-BH-A0BS | 55 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not available | NA | NA | alive | 7.15 | LumA | European | TCGA.BH.A0BS.01A.11R.A12P.07 |
| TCGA-BH-A0BS | 55 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | not available | NA | NA | alive | 7.15 | LumA | European | TCGA.BH.A0BS.11A.11R.A12P.07 |
| TCGA-AR-A1AO | 47 | female | White | Primary solid Tumor | premenopausal | IDC | positive | negative | negative | NA | NA | alive | 7.17 | Normal | European | TCGA.AR.A1AO.01A.11R.A12P.07 |
| TCGA-AR-A1AX | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 7.2 | LumA | European | TCGA.AR.A1AX.01A.11R.A12P.07 |
| TCGA-AR-A1AW | 65 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 7.21 | LumB | European | TCGA.AR.A1AW.01A.21R.A12P.07 |
| TCGA-AR-A2LJ | 40 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | positive | NA | NA | alive | 7.21 | NA | European | TCGA.AR.A2LJ.01A.12R.A19W.07 |
| TCGA-GM-A2DK | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 7.24 | LumA | European | TCGA.GM.A2DK.01A.21R.A180.07 |
| TCGA-PE-A5DE | 41 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 7.24 | LumA | European | TCGA.PE.A5DE.01A.11R.A27Q.07 |
| TCGA-AC-A2FK | 45 | female | White | Primary solid Tumor | not available | ILC | positive | positive | not evaluated | NA | NA | alive | 7.26 | Normal | American | TCGA.AC.A2FK.01A.12R.A180.07 |
| TCGA-E2-A1B1 | 45 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 7.26 | LumA | European | TCGA.E2.A1B1.01A.21R.A12P.07 |
| TCGA-A2-A0CQ | 62 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 7.38 | LumA | African_admix | TCGA.A2.A0CQ.01A.21R.A034.07 |
| TCGA-AR-A250 | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | equivocal | NA | NA | alive | 7.41 | LumB | European | TCGA.AR.A250.01A.31R.A169.07 |
| TCGA-BH-A0C3 | 47 | female | White | Primary solid Tumor | premenopausal | with IDC/ILC phenotypes | positive | negative | negative | metastasis | bone | alive | 7.42 | NA | European | TCGA.BH.A0C3.01A.21R.A12P.07 |
| TCGA-BH-A0C3 | 47 | female | White | Solid Tissue Normal | premenopausal | with IDC/ILC phenotypes | positive | negative | negative | metastasis | bone | alive | 7.42 | NA | European | TCGA.BH.A0C3.11A.23R.A12P.07 |
| TCGA-B6-A0RT | 39 | female | White | Primary solid Tumor | indeterminate | IDC | negative | negative | not evaluated | NA | NA | alive | 7.45 | Basal | European | TCGA.B6.A0RT.01A.21R.A084.07 |
| TCGA-AC-A2FF | 40 | female | Asian | Primary solid Tumor | not available | ILC | positive | positive | not evaluated | NA | NA | alive | 7.55 | LumA | South Asian_admix | TCGA.AC.A2FF.01A.11R.A17B.07 |
| TCGA-AC-A2FF | 40 | female | Asian | Solid Tissue Normal | not available | ILC | positive | positive | not evaluated | NA | NA | alive | 7.55 | LumA | South Asian_admix | TCGA.AC.A2FF.11A.13R.A17B.07 |
| TCGA-BH-A0C7 | 48 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | negative | not available | NA | NA | alive | 7.58 | LumB | European | TCGA.BH.A0C7.01B.11R.A115.07 |
| TCGA-A2-A3XT | 45 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 7.58 | Basal | African | TCGA.A2.A3XT.01A.11R.A22U.07 |
| TCGA-A2-A0CP | 60 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 7.7 | LumA | European | TCGA.A2.A0CP.01A.11R.A034.07 |
| TCGA-AR-A252 | 50 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 7.77 | LumA | European | TCGA.AR.A252.01A.11R.A169.07 |
| TCGA-AR-A1AP | 80 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 7.82 | LumA | European | TCGA.AR.A1AP.01A.11R.A12P.07 |
| TCGA-AR-A1AU | 39 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 7.85 | LumA | European | TCGA.AR.A1AU.01A.11R.A12P.07 |
| TCGA-AR-A1AN | 46 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 7.99 | LumA | European | TCGA.AR.A1AN.01A.11R.A12P.07 |
| TCGA-AO-A1KP | 77 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 8.08 | LumB | European | TCGA.AO.A1KP.01A.11R.A13Q.07 |
| TCGA-AR-A1AL | 60 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 8.13 | LumA | European | TCGA.AR.A1AL.01A.21R.A12P.07 |
| TCGA-AR-A24S | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 8.15 | LumB | European | TCGA.AR.A24S.01A.11R.A169.07 |
| TCGA-AR-A0TQ | 27 | female | White | Primary solid Tumor | premenopausal | IDC | positive | negative | equivocal | NA | NA | alive | 8.19 | LumB | European | TCGA.AR.A0TQ.01A.11R.A084.07 |
| TCGA-AR-A1AM | 52 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 8.19 | NA | European | TCGA.AR.A1AM.01A.41R.A22K.07 |
| TCGA-AR-A24Z | 57 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 8.22 | LumB | European | TCGA.AR.A24Z.01A.11R.A169.07 |
| TCGA-AR-A24X | 52 | female | White | Primary solid Tumor | premenopausal | IDC/ILC | positive | positive | equivocal | NA | NA | alive | 8.22 | NA | European | TCGA.AR.A24X.01A.11R.A169.07 |
| TCGA-A2-A0CV | 41 | female | Asian | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 8.24 | LumA | East Asian | TCGA.A2.A0CV.01A.31R.A115.07 |
| TCGA-A2-A0CL | 37 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 8.25 | Normal | African | TCGA.A2.A0CL.01A.11R.A115.07 |
| TCGA-A2-A0ST | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | not evaluated | NA | NA | alive | 8.26 | Basal | European | TCGA.A2.A0ST.01A.12R.A084.07 |
| TCGA-AR-A1AQ | 49 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 8.27 | Basal | European | TCGA.AR.A1AQ.01A.11R.A12P.07 |
| TCGA-AC-A2BM | 41 | female | Black or African American | Primary solid Tumor | not available | IDC | positive | positive | not evaluated | NA | NA | alive | 8.27 | LumB | African | TCGA.AC.A2BM.01A.11R.A21T.07 |
| TCGA-AR-A251 | 51 | female | White | Primary solid Tumor | premenopausal | IDC | positive | negative | equivocal | NA | NA | alive | 8.3 | Basal | European | TCGA.AR.A251.01A.12R.A169.07 |
| TCGA-AR-A24N | 54 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 8.31 | LumB | European | TCGA.AR.A24N.01A.11R.A169.07 |
| TCGA-B6-A1KF | 68 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 8.45 | Basal | European | TCGA.B6.A1KF.01A.11R.A13Q.07 |
| TCGA-GM-A2DN | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 8.46 | LumA | European | TCGA.GM.A2DN.01A.11R.A180.07 |
| TCGA-A2-A0EM | 73 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 8.47 | LumA | European | TCGA.A2.A0EM.01A.11R.A034.07 |
| TCGA-A2-A04W | 50 | female | White | Primary solid Tumor | premenopausal | apocrine | negative | negative | positive | NA | NA | alive | 8.49 | NA | European | TCGA.A2.A04W.01A.31R.A115.07 |
| TCGA-AO-A12A | 47 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 8.52 | LumA | European | TCGA.AO.A12A.01A.21R.A115.07 |
| TCGA-E2-A1LI | 57 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | NA | NA | alive | 8.54 | Basal | European | TCGA.E2.A1LI.01A.12R.A157.07 |
| TCGA-AR-A24U | 47 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | positive | NA | NA | alive | 8.56 | Her2 | European | TCGA.AR.A24U.01A.11R.A169.07 |
| TCGA-B6-A40B | 76 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 8.63 | LumA | European | TCGA.B6.A40B.01A.11R.A239.07 |
| TCGA-AR-A1AK | 70 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 8.65 | LumA | European | TCGA.AR.A1AK.01A.21R.A12P.07 |
| TCGA-AR-A24Q | 49 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 8.68 | Basal | European | TCGA.AR.A24Q.01A.12R.A169.07 |
| TCGA-AR-A24T | 46 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 8.77 | LumA | European | TCGA.AR.A24T.01A.11R.A169.07 |
| TCGA-AR-A24V | 52 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 8.77 | LumA | European | TCGA.AR.A24V.01A.21R.A169.07 |
| TCGA-A2-A25E | 34 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | locoregional recurrence | chest wall | alive | 8.77 | LumB | African | TCGA.A2.A25E.01A.11R.A169.07 |
| TCGA-GM-A2DM | 57 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 8.83 | LumA | American | TCGA.GM.A2DM.01A.11R.A180.07 |
| TCGA-E2-A1LH | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 8.89 | Basal | European | TCGA.E2.A1LH.01A.11R.A14D.07 |
| TCGA-E2-A1LH | 59 | female | White | Solid Tissue Normal | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 8.89 | Basal | European | TCGA.E2.A1LH.11A.22R.A14D.07 |
| TCGA-AO-A128 | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | alive | 8.89 | Basal | European | TCGA.AO.A128.01A.11R.A10J.07 |
| TCGA-Z7-A8R6 | 46 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | NA | NA | alive | 8.91 | LumB | European | TCGA.Z7.A8R6.01A.11R.A41B.07 |
| TCGA-AR-A0U4 | 54 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 8.93 | Basal | European | TCGA.AR.A0U4.01A.11R.A109.07 |
| TCGA-A2-A25A | 44 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 8.97 | Normal | European | TCGA.A2.A25A.01A.12R.A16F.07 |
| TCGA-A2-A0CR | 54 | female | Asian | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 8.99 | LumA | East Asian | TCGA.A2.A0CR.01A.11R.A22K.07 |
| TCGA-A2-A0CW | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 8.99 | LumB | European | TCGA.A2.A0CW.01A.21R.A115.07 |
| TCGA-AO-A129 | 29 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | alive | 9.0 | Basal | European | TCGA.AO.A129.01A.21R.A10J.07 |
| TCGA-Z7-A8R5 | 61 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | locoregional recurrence | recur>bone | alive | 9.0 | LumA | European | TCGA.Z7.A8R5.01A.42R.A41B.07 |
| TCGA-AR-A1AI | 47 | female | White | Primary solid Tumor | postmenopausal | medullary carcinoma | negative | negative | equivocal | NA | NA | alive | 9.02 | Basal | European | TCGA.AR.A1AI.01A.11R.A12P.07 |
| TCGA-AO-A126 | 39 | female | Asian | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | locoregional recurrence | NA | alive | 9.05 | LumA | East Asian | TCGA.AO.A126.01A.11R.A10J.07 |
| TCGA-AR-A0TT | 53 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | negative | negative | NA | NA | alive | 9.08 | LumB | African_admix | TCGA.AR.A0TT.01A.31R.A084.07 |
| TCGA-GM-A3NW | 63 | female | White | Primary solid Tumor | postmenopausal | ILC | negative | positive | equivocal | NA | NA | alive | 9.2 | LumA | European | TCGA.GM.A3NW.01A.21R.A22K.07 |
| TCGA-BH-A42U | 80 | female | Black or African American | Primary solid Tumor | postmenopausal | ILC | negative | negative | negative | NA | NA | alive | 9.21 | Normal | African | TCGA.BH.A42U.01A.12R.A24H.07 |
| TCGA-AR-A24R | 45 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | alive | 9.39 | LumB | European | TCGA.AR.A24R.01A.11R.A169.07 |
| TCGA-AO-A125 | 72 | female | Black or African American | Primary solid Tumor | postmenopausal | papillary carcinoma | positive | positive | negative | NA | NA | alive | 9.46 | NA | African | TCGA.AO.A125.01A.11R.A10J.07 |
| TCGA-AO-A124 | 38 | female | White | Primary solid Tumor | premenopausal | mucinous/ductal | negative | negative | negative | NA | NA | alive | 9.6 | NA | European | TCGA.AO.A124.01A.11R.A10J.07 |
| TCGA-GM-A2DL | 50 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | positive | negative | NA | NA | alive | 9.63 | LumA | European | TCGA.GM.A2DL.01A.11R.A18M.07 |
| TCGA-A2-A0EP | 56 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | negative | NA | NA | alive | 9.86 | LumA | European | TCGA.A2.A0EP.01A.52R.A22U.07 |
| TCGA-AR-A24O | 43 | female | White | Primary solid Tumor | premenopausal | ILC with ductal features | positive | positive | negative | not available | not available | alive | 9.88 | NA | European | TCGA.AR.A24O.01A.11R.A169.07 |
| TCGA-AR-A24M | 38 | female | White | Primary solid Tumor | premenopausal | IDC/ILC | positive | positive | negative | NA | NA | alive | 10.02 | NA | European | TCGA.AR.A24M.01A.11R.A169.07 |
| TCGA-A2-A04R | 36 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | alive | 10.15 | LumB | African_admix | TCGA.A2.A04R.01A.41R.A109.07 |
| TCGA-AR-A1AH | 51 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | alive | 10.42 | Basal | European | TCGA.AR.A1AH.01A.11R.A12D.07 |
| TCGA-AQ-A04L | 48 | female | White | Primary solid Tumor | perimenopausal | IDC | positive | negative | positive | NA | NA | alive | 10.83 | NA | European | TCGA.AQ.A04L.01B.21R.A10J.07 |
| TCGA-3C-AALI | 50 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | alive | 10.97 | Her2 | African | TCGA.3C.AALI.01A.11R.A41B.07 |
| TCGA-3C-AAAU | 55 | female | White | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | metastasis | lung | alive | 11.08 | LumA | European | TCGA.3C.AAAU.01A.11R.A41B.07 |
| TCGA-AR-A0U3 | 59 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | alive | 11.17 | LumA | European | TCGA.AR.A0U3.01A.11R.A109.07 |
| TCGA-A2-A0EN | 70 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | alive | 11.19 | LumA | European | TCGA.A2.A0EN.01A.13R.A084.07 |
| TCGA-A2-A0CK | 60 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | new primary | contralateral | alive | 11.39 | LumA | European | TCGA.A2.A0CK.01A.11R.A22K.07 |
| TCGA-B6-A1KN | 57 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | not evaluated | NA | NA | alive | 11.59 | LumB | European | TCGA.B6.A1KN.01A.11R.A13Q.07 |
| TCGA-AR-A0TP | 43 | female | White | Primary solid Tumor | premenopausal | IDC | positive | negative | negative | NA | NA | alive | 11.7 | Basal | European | TCGA.AR.A0TP.01A.11R.A084.07 |
| TCGA-B6-A0IQ | 40 | female | White | Primary solid Tumor | indeterminate | IDC | negative | negative | not evaluated | NA | NA | alive | 11.73 | Basal | European | TCGA.B6.A0IQ.01A.11R.A034.07 |
| TCGA-A2-A04N | 66 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 11.92 | LumA | European | TCGA.A2.A04N.01A.11R.A115.07 |
| TCGA-B6-A0I2 | 45 | female | White | Primary solid Tumor | indeterminate | IDC | not evaluated | not evaluated | not evaluated | NA | NA | alive | 11.94 | Basal | European | TCGA.B6.A0I2.01A.11R.A034.07 |
| TCGA-AR-A24H | 65 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | alive | 13.4 | LumB | European | TCGA.AR.A24H.01A.11R.A169.07 |
| TCGA-B6-A0RO | 71 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | alive | 13.49 | LumA | European | TCGA.B6.A0RO.01A.22R.A084.07 |
| TCGA-B6-A0IO | 66 | female | White | Primary solid Tumor | indeterminate | IDC | positive | Indeterminate | not evaluated | NA | NA | alive | 13.8 | LumA | European | TCGA.B6.A0IO.01A.11R.A034.07 |
| TCGA-AR-A2LE | 69 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | not evaluated | new primary | endoometrium | alive | 13.86 | LumA | European | TCGA.AR.A2LE.01A.11R.A180.07 |
| TCGA-B6-A0RV | 42 | female | White | Primary solid Tumor | indeterminate | IDC/ILC | positive | positive | not evaluated | NA | NA | alive | 14.12 | NA | European | TCGA.B6.A0RV.01A.11R.A084.07 |
| TCGA-B6-A0WT | 61 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | new primary | contralateral | alive | 15.71 | LumA | European | TCGA.B6.A0WT.01A.11R.A109.07 |
| TCGA-B6-A0IJ | 42 | female | Black or African American | Primary solid Tumor | indeterminate | IDC | positive | positive | not evaluated | NA | NA | alive | 19.46 | Basal | African | TCGA.B6.A0IJ.01A.11R.A034.07 |
| TCGA-B6-A0RI | 44 | female | White | Primary solid Tumor | indeterminate | IDC | positive | positive | not evaluated | locoregional disease | chest wall | alive | 19.51 | LumA | European | TCGA.B6.A0RI.01A.11R.A056.07 |
| TCGA-B6-A0RE | 61 | female | Black or African American | Primary solid Tumor | indeterminate | IDC | negative | negative | not evaluated | NA | NA | alive | 21.29 | Basal | African_admix | TCGA.B6.A0RE.01A.11R.A056.07 |
| TCGA-B6-A0RN | 60 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | not evaluated | NA | NA | alive | 21.92 | LumA | European | TCGA.B6.A0RN.01A.12R.A084.07 |
| TCGA-B6-A0IA | 51 | female | White | Primary solid Tumor | indeterminate | ductal/cribiform | positive | positive | not evaluated | NA | NA | alive | 22.97 | NA | European | TCGA.B6.A0IA.01A.11R.A034.07 |
| TCGA-B6-A0I5 | 49 | female | White | Primary solid Tumor | indeterminate | IDC | positive | positive | not evaluated | NA | NA | alive | 23.43 | LumA | European | TCGA.B6.A0I5.01A.11R.A034.07 |
| TCGA-B6-A0RU | 40 | female | White | Primary solid Tumor | indeterminate | ductal/metaplastic | negative | negative | not evaluated | NA | NA | alive | 23.56 | NA | European | TCGA.B6.A0RU.01A.11R.A084.07 |
| TCGA-AC-A23H | 90 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | NA | NA | dead | NA | Her2 | European | TCGA.AC.A23H.01A.11R.A157.07 |
| TCGA-AC-A23H | 90 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | negative | positive | NA | NA | dead | NA | Her2 | European | TCGA.AC.A23H.11A.12R.A157.07 |
| TCGA-E9-A1N6 | 52 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | metastasis | bone>recur>liver | dead | NA | NA | European | TCGA.E9.A1N6.01A.11R.A144.07 |
| TCGA-E9-A1N6 | 52 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | positive | metastasis | bone>recur>liver | dead | NA | NA | European | TCGA.E9.A1N6.11A.32R.A144.07 |
| TCGA-E9-A1NG | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | NA | LumA | European | TCGA.E9.A1NG.01A.21R.A14M.07 |
| TCGA-E9-A1NG | 62 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | NA | LumA | European | TCGA.E9.A1NG.11A.52R.A14M.07 |
| TCGA-E9-A1NF | 60 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | positive | positive | negative | NA | NA | dead | NA | NA | European | TCGA.E9.A1NF.01A.11R.A14D.07 |
| TCGA-E9-A1NF | 60 | female | White | Solid Tissue Normal | postmenopausal | IDC/ILC | positive | positive | negative | NA | NA | dead | NA | NA | European | TCGA.E9.A1NF.11A.73R.A14D.07 |
| TCGA-C8-A3M7 | 60 | female | Asian | Primary solid Tumor | postmenopausal | ILC | negative | negative | negative | locoregional recurrence | NA | dead | 0.0 | LumA | East Asian | TCGA.C8.A3M7.01A.12R.A21T.07 |
| TCGA-AC-A62V | 58 | male | Black or African American | Primary solid Tumor | not applicable | IDC | positive | positive | not evaluated | metastasis | bone | dead | 0.01 | NA | African | TCGA.AC.A62V.01A.11R.A31O.07 |
| TCGA-C8-A12Q | 78 | female | Asian | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | metastasis | liver | dead | 0.01 | Her2 | East Asian | TCGA.C8.A12Q.01A.11R.A115.07 |
| TCGA-E9-A2JS | 72 | female | White | Primary solid Tumor | postmenopausal | ILC | not evaluated | not evaluated | not evaluated | metastasis | bone|liver | dead | 0.04 | LumB | European | TCGA.E9.A2JS.01A.11R.A180.07 |
| TCGA-E9-A226 | 45 | female | White | Primary solid Tumor | premenopausal | IDC | not evaluated | not evaluated | not evaluated | metastasis | bone|liver | dead | 0.04 | LumB | European | TCGA.E9.A226.01A.21R.A157.07 |
| TCGA-AC-A3EH | 79 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | negative | negative | NA | NA | dead | 0.05 | NA | European | TCGA.AC.A3EH.01A.22R.A22K.07 |
| TCGA-E9-A1RB | 40 | female | White | Primary solid Tumor | premenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | dead | 0.06 | LumB | European | TCGA.E9.A1RB.01A.11R.A157.07 |
| TCGA-E9-A1RB | 40 | female | White | Solid Tissue Normal | premenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | dead | 0.06 | LumB | European | TCGA.E9.A1RB.11A.33R.A157.07 |
| TCGA-E9-A245 | 47 | female | White | Primary solid Tumor | premenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | dead | 0.07 | LumA | European | TCGA.E9.A245.01A.22R.A16F.07 |
| TCGA-A8-A08L | 89 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | dead | 0.08 | Her2 | European | TCGA.A8.A08L.01A.11R.A00Z.07 |
| TCGA-BH-A42T | 75 | female | Black or African American | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | dead | 0.88 | NA | African_admix | TCGA.BH.A42T.01A.11R.A24H.07 |
| TCGA-AC-A2QJ | 48 | female | White | Primary solid Tumor | perimenopausal | metaplastic carcinoma | negative | negative | negative | metastasis | bone | dead | 1.22 | NA | American | TCGA.AC.A2QJ.01A.12R.A19W.07 |
| TCGA-D8-A1XC | 85 | female | White | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | negative | metastasis | bone | dead | 1.03 | NA | European | TCGA.D8.A1XC.01A.11R.A14D.07 |
| TCGA-D8-A1Y1 | 80 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 0.83 | LumB | European | TCGA.D8.A1Y1.01A.21R.A14M.07 |
| TCGA-LL-A73Z | 55 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | metastasis | skin | dead | 0.62 | Normal | African | TCGA.LL.A73Z.01A.11R.A32P.07 |
| TCGA-A2-A0CU | 73 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | dead | 0.43 | LumA | European | TCGA.A2.A0CU.01A.12R.A034.07 |
| TCGA-E2-A15M | 66 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | dead | 0.92 | LumA | European | TCGA.E2.A15M.01A.11R.A12D.07 |
| TCGA-E2-A15M | 66 | female | White | Solid Tissue Normal | postmenopausal | ILC | positive | positive | negative | NA | NA | dead | 0.92 | LumA | European | TCGA.E2.A15M.11A.22R.A12D.07 |
| TCGA-D8-A73W | 79 | female | White | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | negative | negative | metastasis | lung|bone | dead | 1.05 | NA | European | TCGA.D8.A73W.01A.22R.A352.07 |
| TCGA-A2-A0T2 | 66 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | metastasis | liver|abdomen | dead | 0.7 | Basal | European | TCGA.A2.A0T2.01A.11R.A084.07 |
| TCGA-AQ-A7U7 | 55 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | dead | 1.6 | LumA | European | TCGA.AQ.A7U7.01A.22R.A352.07 |
| TCGA-E2-A2P5 | 78 | female | Black or African American | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | metastasis | bone | dead | 2.25 | NA | admix | TCGA.E2.A2P5.01A.11R.A19W.07 |
| TCGA-OL-A5D6 | 71 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | not evaluated | NA | NA | dead | 3.02 | Normal | African_admix | TCGA.OL.A5D6.01A.21R.A27Q.07 |
| TCGA-E2-A14Z | 64 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | metastasis | bone | dead | 1.54 | LumA | European | TCGA.E2.A14Z.01A.11R.A115.07 |
| TCGA-A2-A04P | 36 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | negative | negative | not evaluated | metastasis | bone>axilla recur|lung>liver | dead | 1.5 | Basal | African | TCGA.A2.A04P.01A.31R.A034.07 |
| TCGA-A7-A13E | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | equivocal | metastasis | lung|bone|liver|brain|skin | dead | 1.68 | Basal | European | TCGA.A7.A13E.01A.11R.A12P.07 |
| TCGA-A7-A13E | 62 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | negative | equivocal | metastasis | lung|bone|liver|brain|skin | dead | 1.68 | Basal | European | TCGA.A7.A13E.11A.61R.A12P.07 |
| TCGA-A2-A0YT | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | not evaluated | NA | NA | dead | 1.98 | LumB | European | TCGA.A2.A0YT.01A.11R.A109.07 |
| TCGA-AO-A0J5 | 48 | female | White | Primary solid Tumor | premenopausal | ductal/micropapillary | positive | negative | equivocal | metastasis | lung|bone|liver | dead | 2.17 | NA | European | TCGA.AO.A0J5.01A.11R.A034.07 |
| TCGA-A2-A0CM | 40 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | dead | 2.06 | Basal | African_admix | TCGA.A2.A0CM.01A.31R.A034.07 |
| TCGA-A2-A0EW | 53 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | metastasis | bone | dead | 5.16 | LumA | European | TCGA.A2.A0EW.01A.21R.A115.07 |
| TCGA-BH-A0BF | 56 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 3.62 | LumB | European | TCGA.BH.A0BF.01A.21R.A12P.07 |
| TCGA-A2-A3XY | 49 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | metastasis | lung>lymph nodes>brain | dead | 2.99 | NA | African | TCGA.A2.A3XY.01A.11R.A239.07 |
| TCGA-AC-A2FE | 62 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | NA | bone>liver | dead | 7.22 | NA | European | TCGA.AC.A2FE.01A.11R.A19W.07 |
| TCGA-A2-A0SV | 63 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | metastasis | bone | dead | 2.26 | LumB | European | TCGA.A2.A0SV.01A.11R.A084.07 |
| TCGA-A8-A06U | 80 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | dead | 2.42 | LumA | European | TCGA.A8.A06U.01A.11R.A00Z.07 |
| TCGA-E2-A1B4 | 74 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 2.75 | LumA | European | TCGA.E2.A1B4.01A.11R.A12P.07 |
| TCGA-A2-A3XU | 35 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | not evaluated | metastasis | bone>breast recur|chest wall | dead | 2.5 | Basal | African_admix | TCGA.A2.A3XU.01A.12R.A22U.07 |
| TCGA-A8-A06X | 77 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | negative | positive | NA | NA | dead | 2.58 | LumB | European | TCGA.A8.A06X.01A.21R.A00Z.07 |
| TCGA-A1-A0SK | 54 | female | Asian | Primary solid Tumor | indeterminate | \neuroendocrine carcinoma, large-cell type, high-grade\"" | negative | negative | negative | NA | NA | dead | 2.65 | NA | East Asian | TCGA.A1.A0SK.01A.12R.A084.07 |
| TCGA-OL-A66K | 72 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | NA | NA | dead | 3.49 | LumA | European | TCGA.OL.A66K.01A.11R.A29R.07 |
| TCGA-A2-A3XS | 62 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | not evaluated | metastasis | lung | dead | 2.83 | NA | African_admix | TCGA.A2.A3XS.01A.11R.A22U.07 |
| TCGA-A8-A08J | 52 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | NA | NA | dead | 3.09 | Her2 | European | TCGA.A8.A08J.01A.11R.A00Z.07 |
| TCGA-B6-A3ZX | 50 | female | Black or African American | Primary solid Tumor | unknown | IDC/ILC | negative | negative | negative | metastasis | bone | dead | 3.15 | NA | African | TCGA.B6.A3ZX.01A.11R.A239.07 |
| TCGA-A2-A3XX | 49 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | NA | NA | dead | 3.94 | Basal | African | TCGA.A2.A3XX.01A.21R.A239.07 |
| TCGA-AR-A2LK | 62 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | equivocal | metastasis | bone | dead | 4.51 | LumB | European | TCGA.AR.A2LK.01A.11R.A180.07 |
| TCGA-BH-A0C1 | 61 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | metastasis | bone | dead | 3.86 | LumA | European | TCGA.BH.A0C1.01B.11R.A12D.07 |
| TCGA-A2-A0SW | 82 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | not evaluated | metastasis | liver | dead | 3.74 | LumB | European | TCGA.A2.A0SW.01A.11R.A084.07 |
| TCGA-A2-A0CO | 85 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | dead | 4.02 | NA | European | TCGA.A2.A0CO.01A.13R.A22K.07 |
| TCGA-BH-A0BP | 76 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 6.29 | LumA | European | TCGA.BH.A0BP.01A.11R.A115.07 |
| TCGA-HN-A2OB | 45 | female | not available | Primary solid Tumor | premenopausal | ILC | positive | positive | negative | metastasis | bone|omentum | dead | 5.2 | LumA | European | TCGA.HN.A2OB.01A.21R.A27Q.07 |
| TCGA-A2-A04V | 39 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | dead | 5.26 | LumA | European | TCGA.A2.A04V.01A.21R.A034.07 |
| TCGA-AR-A24L | 26 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | NA | NA | dead | 7.85 | LumA | European | TCGA.AR.A24L.01A.11R.A169.07 |
| TCGA-AR-A0TZ | 43 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | equivocal | metastasis | bone | dead | 8.93 | LumA | European | TCGA.AR.A0TZ.01A.12R.A084.07 |
| TCGA-A2-A0CS | 73 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | metastasis | ovary | dead | 6.43 | LumA | European | TCGA.A2.A0CS.01A.11R.A115.07 |
| TCGA-AO-A03P | 54 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | metastasis | liver | dead | 7.97 | LumB | African | TCGA.AO.A03P.01A.11R.A00Z.07 |
| TCGA-B6-A0IP | 74 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | NA | NA | dead | 10.75 | LumA | European | TCGA.B6.A0IP.01A.11R.A034.07 |
| TCGA-A8-A08T | 64 | female | not available | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | not available | not available | dead | 9.33 | LumA | European | TCGA.A8.A08T.01A.21R.A00Z.07 |
| TCGA-B6-A0IM | 75 | female | Black or African American | Primary solid Tumor | postmenopausal | ductal/cribiform | positive | positive | not evaluated | NA | NA | dead | 10.6 | NA | African | TCGA.B6.A0IM.01A.11R.A034.07 |
| TCGA-B6-A0X1 | 48 | female | White | Primary solid Tumor | indeterminate | IDC | negative | negative | not evaluated | NA | NA | dead | 20.41 | Basal | European | TCGA.B6.A0X1.01A.11R.A109.07 |
| TCGA-B6-A0RH | 51 | female | Black or African American | Primary solid Tumor | indeterminate | IDC | positive | positive | not evaluated | NA | NA | dead | 17.68 | Her2 | African | TCGA.B6.A0RH.01A.21R.A115.07 |
| TCGA-GM-A2DA | 46 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | metastasis | bone>liver>lymph node>brain | dead | 18.05 | LumA | European | TCGA.GM.A2DA.01A.11R.A18M.07 |
| TCGA-B6-A0IC | 90 | female | White | Primary solid Tumor | postmenopausal | invasive papillary | positive | positive | not evaluated | NA | NA | dead | NA | NA | European | TCGA.B6.A0IC.01A.11R.A034.07 |
| TCGA-BH-A1F8 | 90 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | dead | NA | LumB | European | TCGA.BH.A1F8.01A.11R.A13Q.07 |
| TCGA-BH-A1F8 | 90 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | positive | NA | NA | dead | NA | LumB | European | TCGA.BH.A1F8.11B.21R.A13Q.07 |
| TCGA-UU-A93S | 63 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | metastasis | bone|liver | dead | 0.32 | Her2 | African_admix | TCGA.UU.A93S.01A.21R.A41B.07 |
| TCGA-AR-A0TR | 68 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | equivocal | NA | NA | dead | 0.44 | LumA | European | TCGA.AR.A0TR.01A.11R.A084.07 |
| TCGA-AQ-A0Y5 | 70 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | dead | 0.47 | LumA | European | TCGA.AQ.A0Y5.01A.11R.A14M.07 |
| TCGA-BH-A18T | 70 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | dead | 0.61 | Basal | European | TCGA.BH.A18T.01A.11R.A12D.07 |
| TCGA-EW-A1P8 | 58 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | metastasis | lung|bone|liver|skin | dead | 0.65 | Basal | European | TCGA.EW.A1P8.01A.11R.A144.07 |
| TCGA-E2-A1LK | 84 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | equivocal | locoregional recurrence | axilla | dead | 0.73 | Basal | African_admix | TCGA.E2.A1LK.01A.21R.A14D.07 |
| TCGA-BH-A8FY | 87 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | negative | NA | NA | dead | 0.81 | LumA | European | TCGA.BH.A8FY.01A.11R.A36F.07 |
| TCGA-AR-A5QQ | 68 | female | White | Primary solid Tumor | postmenopausal | squamous (metaplastic) carcinoma | negative | negative | negative | locoregional recurrence | chest wall|lung|liver|bone|adrenal glands | dead | 0.88 | NA | European | TCGA.AR.A5QQ.01A.11R.A28M.07 |
| TCGA-B6-A0I9 | 62 | female | White | Primary solid Tumor | indeterminate | IDC | Indeterminate | positive | not evaluated | metastasis | bone | dead | 0.99 | Her2 | European | TCGA.B6.A0I9.01A.11R.A034.07 |
| TCGA-BH-A1EV | 45 | female | White | Primary solid Tumor | not available | IDC | positive | positive | positive | NA | NA | dead | 1.0 | Her2 | European | TCGA.BH.A1EV.01A.11R.A137.07 |
| TCGA-BH-A1EV | 45 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | positive | NA | NA | dead | 1.0 | Her2 | European | TCGA.BH.A1EV.11A.24R.A137.07 |
| TCGA-A8-A09X | 62 | female | not available | Primary solid Tumor | postmenopausal | ILC | negative | negative | negative | NA | NA | dead | 1.17 | Her2 | European | TCGA.A8.A09X.01A.11R.A00Z.07 |
| TCGA-BH-A18N | 88 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | dead | 1.28 | LumA | European | TCGA.BH.A18N.01A.11R.A12D.07 |
| TCGA-BH-A18N | 88 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | negative | NA | NA | dead | 1.28 | LumA | European | TCGA.BH.A18N.11A.43R.A12D.07 |
| TCGA-AR-A1AR | 50 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | negative | new primary | contralateral | dead | 1.43 | Basal | European | TCGA.AR.A1AR.01A.31R.A137.07 |
| TCGA-BH-A1EY | 79 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | metastasis | lung|liver | dead | 1.47 | LumA | European | TCGA.BH.A1EY.01A.11R.A13Q.07 |
| TCGA-B6-A0WW | 58 | female | Black or African American | Primary solid Tumor | indeterminate | IDC | positive | positive | not evaluated | metastasis | brain | dead | 1.53 | LumB | African | TCGA.B6.A0WW.01A.11R.A109.07 |
| TCGA-B6-A0IK | 63 | female | White | Primary solid Tumor | indeterminate | IDC | negative | negative | not evaluated | metastasis | lung | dead | 1.56 | Her2 | European | TCGA.B6.A0IK.01A.12R.A056.07 |
| TCGA-B6-A409 | 44 | female | Black or African American | Primary solid Tumor | premenopausal | IDC | negative | negative | equivocal | metastasis | lung | dead | 1.57 | Basal | African | TCGA.B6.A409.01A.11R.A24H.07 |
| TCGA-BH-A1FG | 88 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 1.58 | LumA | European | TCGA.BH.A1FG.01A.11R.A13Q.07 |
| TCGA-BH-A1FG | 88 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 1.58 | LumA | European | TCGA.BH.A1FG.11B.12R.A13Q.07 |
| TCGA-BH-A18J | 56 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | metastasis | bone | dead | 1.68 | LumA | European | TCGA.BH.A18J.01A.11R.A12D.07 |
| TCGA-BH-A18J | 56 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | negative | metastasis | bone | dead | 1.68 | LumA | European | TCGA.BH.A18J.11A.31R.A12D.07 |
| TCGA-AR-A2LH | 55 | female | White | Primary solid Tumor | postmenopausal | ILC | negative | negative | equivocal | metastasis | bone|liver | dead | 1.69 | Normal | European | TCGA.AR.A2LH.01A.31R.A18M.07 |
| TCGA-B6-A0WX | 40 | female | Black or African American | Primary solid Tumor | premenopausal | pleomorphic/lobular | negative | negative | not evaluated | metastasis | bone | dead | 1.75 | NA | African | TCGA.B6.A0WX.01A.11R.A109.07 |
| TCGA-B6-A0I8 | 46 | female | White | Primary solid Tumor | indeterminate | IDC | not evaluated | not evaluated | not evaluated | locoregional disease | pectoral muscle | dead | 2.05 | NA | European | TCGA.B6.A0I8.01A.11R.A034.07 |
| TCGA-BH-A1F0 | 80 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | Indeterminate | negative | NA | NA | dead | 2.15 | Basal | European | TCGA.BH.A1F0.01A.11R.A137.07 |
| TCGA-BH-A1F0 | 80 | female | White | Solid Tissue Normal | postmenopausal | IDC | negative | Indeterminate | negative | NA | NA | dead | 2.15 | Basal | European | TCGA.BH.A1F0.11B.23R.A137.07 |
| TCGA-AC-A2FM | 87 | female | White | Primary solid Tumor | postmenopausal | ILC | not evaluated | not evaluated | not evaluated | metastasis | bone marrow | dead | 2.17 | NA | European | TCGA.AC.A2FM.01A.11R.A19W.07 |
| TCGA-AC-A2FM | 87 | female | White | Solid Tissue Normal | postmenopausal | ILC | not evaluated | not evaluated | not evaluated | metastasis | bone marrow | dead | 2.17 | NA | European | TCGA.AC.A2FM.11B.32R.A19W.07 |
| TCGA-BH-A18L | 50 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | dead | 2.22 | LumB | European | TCGA.BH.A18L.01A.32R.A12D.07 |
| TCGA-BH-A18L | 50 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | negative | NA | NA | dead | 2.22 | LumB | European | TCGA.BH.A18L.11A.42R.A12D.07 |
| TCGA-B6-A0X4 | 62 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | metastasis | bone | dead | 2.35 | LumA | European | TCGA.B6.A0X4.01A.11R.A109.07 |
| TCGA-E2-A1LE | 71 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | metastasis | lung | dead | 2.41 | NA | European | TCGA.E2.A1LE.01A.12R.A19W.07 |
| TCGA-BH-A18P | 60 | female | White | Primary solid Tumor | not available | IDC | positive | negative | positive | NA | NA | dead | 2.52 | Her2 | European | TCGA.BH.A18P.01A.11R.A12D.07 |
| TCGA-BH-A18P | 60 | female | White | Solid Tissue Normal | not available | IDC | positive | negative | positive | NA | NA | dead | 2.52 | Her2 | European | TCGA.BH.A18P.11A.43R.A12D.07 |
| TCGA-BH-A1F2 | 53 | female | White | Primary solid Tumor | not available | IDC | positive | positive | positive | NA | NA | dead | 2.63 | LumB | European | TCGA.BH.A1F2.01A.31R.A13Q.07 |
| TCGA-BH-A1F2 | 53 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | positive | NA | NA | dead | 2.63 | LumB | European | TCGA.BH.A1F2.11A.32R.A13Q.07 |
| TCGA-B6-A0I6 | 49 | female | Black or African American | Primary solid Tumor | indeterminate | IDC | negative | negative | not evaluated | metastasis | bone|skin | dead | 2.71 | NA | African | TCGA.B6.A0I6.01A.11R.A034.07 |
| TCGA-BH-A0EA | 72 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 2.71 | LumA | European | TCGA.BH.A0EA.01A.11R.A115.07 |
| TCGA-BH-A1FD | 68 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 2.76 | LumB | European | TCGA.BH.A1FD.01A.11R.A13Q.07 |
| TCGA-BH-A1FD | 68 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 2.76 | LumB | European | TCGA.BH.A1FD.11B.21R.A13Q.07 |
| TCGA-BH-A1FH | 47 | female | White | Primary solid Tumor | not available | IDC | positive | negative | not evaluated | metastasis | bone | dead | 2.83 | LumA | European | TCGA.BH.A1FH.01A.12R.A13Q.07 |
| TCGA-BH-A1FH | 47 | female | White | Solid Tissue Normal | not available | IDC | positive | negative | not evaluated | metastasis | bone | dead | 2.83 | LumA | European | TCGA.BH.A1FH.11B.42R.A13Q.07 |
| TCGA-BH-A18R | 50 | female | White | Primary solid Tumor | not available | IDC | Indeterminate | negative | positive | NA | NA | dead | 3.13 | Her2 | European | TCGA.BH.A18R.01A.11R.A12D.07 |
| TCGA-BH-A18R | 50 | female | White | Solid Tissue Normal | not available | IDC | Indeterminate | negative | positive | NA | NA | dead | 3.13 | Her2 | European | TCGA.BH.A18R.11A.42R.A12D.07 |
| TCGA-BH-A203 | 78 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | dead | 3.21 | Her2 | European | TCGA.BH.A203.01A.12R.A169.07 |
| TCGA-BH-A203 | 78 | female | White | Solid Tissue Normal | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | dead | 3.21 | Her2 | European | TCGA.BH.A203.11A.42R.A169.07 |
| TCGA-AR-A1AT | 62 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | dead | 3.48 | NA | European | TCGA.AR.A1AT.01A.11R.A12P.07 |
| TCGA-BH-A1EU | 83 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 3.52 | LumA | European | TCGA.BH.A1EU.01A.11R.A137.07 |
| TCGA-BH-A1EU | 83 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 3.52 | LumA | European | TCGA.BH.A1EU.11A.23R.A137.07 |
| TCGA-BH-A1FM | 44 | female | White | Primary solid Tumor | not available | IDC | positive | negative | not evaluated | NA | NA | dead | 3.8 | LumB | European | TCGA.BH.A1FM.01A.11R.A13Q.07 |
| TCGA-BH-A1FM | 44 | female | White | Solid Tissue Normal | not available | IDC | positive | negative | not evaluated | NA | NA | dead | 3.8 | LumB | European | TCGA.BH.A1FM.11B.23R.A13Q.07 |
| TCGA-PE-A5DC | 72 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | positive | NA | NA | dead | 3.92 | LumA | European | TCGA.PE.A5DC.01A.12R.A27Q.07 |
| TCGA-BH-A1EX | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | dead | 4.13 | LumA | East Asian | TCGA.BH.A1EX.01A.11R.A13Q.07 |
| TCGA-BH-A18U | 72 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | positive | NA | NA | dead | 4.28 | LumB | European | TCGA.BH.A18U.01A.21R.A12D.07 |
| TCGA-BH-A18U | 72 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | positive | NA | NA | dead | 4.28 | LumB | European | TCGA.BH.A18U.11A.23R.A12D.07 |
| TCGA-BH-A1FR | 73 | female | White | Primary solid Tumor | not available | IDC/mucinous | positive | positive | not evaluated | NA | NA | dead | 4.5 | NA | European | TCGA.BH.A1FR.01A.11R.A13Q.07 |
| TCGA-BH-A1FR | 73 | female | White | Solid Tissue Normal | not available | IDC/mucinous | positive | positive | not evaluated | NA | NA | dead | 4.5 | NA | European | TCGA.BH.A1FR.11B.42R.A13Q.07 |
| TCGA-BH-A1FL | 69 | female | White | Primary solid Tumor | not available | IDC | positive | positive | not evaluated | NA | NA | dead | 4.58 | LumA | European | TCGA.BH.A1FL.01A.11R.A13Q.07 |
| TCGA-BH-A1FU | 44 | female | White | Primary solid Tumor | not available | IDC | negative | negative | not evaluated | NA | NA | dead | 4.62 | Normal | European | TCGA.BH.A1FU.01A.11R.A14D.07 |
| TCGA-BH-A1FU | 44 | female | White | Solid Tissue Normal | not available | IDC | negative | negative | not evaluated | NA | NA | dead | 4.62 | Normal | European | TCGA.BH.A1FU.11A.23R.A14D.07 |
| TCGA-BH-A18Q | 56 | female | White | Primary solid Tumor | not available | IDC | negative | negative | positive | NA | NA | dead | 4.63 | Basal | European | TCGA.BH.A18Q.01A.12R.A12D.07 |
| TCGA-BH-A18Q | 56 | female | White | Solid Tissue Normal | not available | IDC | negative | negative | positive | NA | NA | dead | 4.63 | Basal | European | TCGA.BH.A18Q.11A.34R.A12D.07 |
| TCGA-BH-A1EW | 38 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | NA | NA | dead | 4.64 | LumA | European | TCGA.BH.A1EW.01A.11R.A137.07 |
| TCGA-BH-A1EW | 38 | female | White | Solid Tissue Normal | premenopausal | IDC | negative | negative | negative | NA | NA | dead | 4.64 | LumA | European | TCGA.BH.A1EW.11B.33R.A137.07 |
| TCGA-AR-A0TY | 54 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | negative | negative | metastasis | bone | dead | 4.65 | LumB | European | TCGA.AR.A0TY.01A.12R.A115.07 |
| TCGA-BH-A208 | 48 | female | White | Primary solid Tumor | not available | IDC | not evaluated | not evaluated | not evaluated | NA | NA | dead | 4.82 | Normal | European | TCGA.BH.A208.01A.11R.A157.07 |
| TCGA-BH-A208 | 48 | female | White | Solid Tissue Normal | not available | IDC | not evaluated | not evaluated | not evaluated | NA | NA | dead | 4.82 | Normal | European | TCGA.BH.A208.11A.51R.A157.07 |
| TCGA-B6-A0X7 | 62 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | positive | positive | not evaluated | new primary | colon | dead | 4.88 | NA | European | TCGA.B6.A0X7.01A.11R.A10J.07 |
| TCGA-AO-A03U | 31 | female | White | Primary solid Tumor | premenopausal | secretory | negative | negative | negative | NA | NA | dead | 4.91 | NA | European | TCGA.AO.A03U.01B.21R.A10J.07 |
| TCGA-GM-A2D9 | 69 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | metastasis | bone>lymph node|lung | dead | 4.96 | LumA | European | TCGA.GM.A2D9.01A.11R.A18M.07 |
| TCGA-BH-A1FJ | 66 | female | White | Primary solid Tumor | not available | IDC | negative | positive | not evaluated | NA | NA | dead | 5.28 | LumB | European | TCGA.BH.A1FJ.01A.11R.A13Q.07 |
| TCGA-BH-A1FJ | 66 | female | White | Solid Tissue Normal | not available | IDC | negative | positive | not evaluated | NA | NA | dead | 5.28 | LumB | European | TCGA.BH.A1FJ.11B.42R.A13Q.07 |
| TCGA-B6-A0IE | 38 | female | Black or African American | Primary solid Tumor | premenopausal | IDC/ILC | negative | negative | not evaluated | metastasis | bone | dead | 5.46 | NA | African_admix | TCGA.B6.A0IE.01A.11R.A034.07 |
| TCGA-BH-A18S | 79 | female | White | Primary solid Tumor | postmenopausal | mucinous carcinoma | positive | positive | negative | NA | NA | dead | 5.5 | NA | European | TCGA.BH.A18S.01A.11R.A12D.07 |
| TCGA-BH-A18S | 79 | female | White | Solid Tissue Normal | postmenopausal | mucinous carcinoma | positive | positive | negative | NA | NA | dead | 5.5 | NA | European | TCGA.BH.A18S.11A.43R.A12D.07 |
| TCGA-B6-A0X5 | 61 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | metastasis | bone|liver|pleura | dead | 5.74 | LumB | African_admix | TCGA.B6.A0X5.01A.21R.A109.07 |
| TCGA-BH-A1EN | 78 | female | White | Primary solid Tumor | postmenopausal | IDC | negative | negative | positive | NA | NA | dead | 5.82 | Her2 | European | TCGA.BH.A1EN.01A.11R.A13Q.07 |
| TCGA-BH-A1EN | 78 | female | White | Solid Tissue Normal | postmenopausal | IDC | negative | negative | positive | NA | NA | dead | 5.82 | Her2 | European | TCGA.BH.A1EN.11A.23R.A13Q.07 |
| TCGA-BH-A1FN | 34 | female | White | Primary solid Tumor | not available | IDC | positive | positive | not evaluated | NA | NA | dead | 6.0 | LumB | European | TCGA.BH.A1FN.01A.11R.A13Q.07 |
| TCGA-BH-A1FN | 34 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | not evaluated | NA | NA | dead | 6.0 | LumB | European | TCGA.BH.A1FN.11A.34R.A13Q.07 |
| TCGA-BH-A18M | 39 | female | White | Primary solid Tumor | not available | IDC | positive | positive | positive | NA | NA | dead | 6.04 | LumA | European | TCGA.BH.A18M.01A.11R.A12D.07 |
| TCGA-BH-A18M | 39 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | positive | NA | NA | dead | 6.04 | LumA | European | TCGA.BH.A18M.11A.33R.A12D.07 |
| TCGA-BH-A1FE | 31 | female | White | Primary solid Tumor | not available | IDC | positive | positive | not evaluated | NA | NA | dead | 6.22 | LumA | European | TCGA.BH.A1FE.01A.11R.A13Q.07 |
| TCGA-BH-A1FE | 31 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | not evaluated | NA | NA | dead | 6.22 | LumA | European | TCGA.BH.A1FE.11B.14R.A13Q.07 |
| TCGA-B6-A0I1 | 73 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | negative | negative | not evaluated | metastasis | lung | dead | 6.46 | Basal | African_admix | TCGA.B6.A0I1.01A.11R.A21T.07 |
| TCGA-B6-A0RM | 57 | female | Black or African American | Primary solid Tumor | indeterminate | IDC | positive | positive | not evaluated | NA | NA | dead | 6.5 | LumA | African_admix | TCGA.B6.A0RM.01A.11R.A084.07 |
| TCGA-B6-A0WV | 67 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | not evaluated | NA | NA | dead | 6.62 | LumB | European | TCGA.B6.A0WV.01A.11R.A109.07 |
| TCGA-B6-A0RL | 60 | female | Black or African American | Primary solid Tumor | not available | IDC | positive | positive | not evaluated | NA | NA | dead | 6.76 | LumB | African | TCGA.B6.A0RL.01A.11R.A084.07 |
| TCGA-AO-A03O | 69 | female | Black or African American | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 6.8 | LumB | African_admix | TCGA.AO.A03O.01A.11R.A00Z.07 |
| TCGA-BH-A1ET | 55 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | dead | 6.9 | LumA | European | TCGA.BH.A1ET.01A.11R.A137.07 |
| TCGA-BH-A1ET | 55 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | negative | NA | NA | dead | 6.9 | LumA | European | TCGA.BH.A1ET.11B.23R.A137.07 |
| TCGA-BH-A204 | 80 | female | White | Primary solid Tumor | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | dead | 6.94 | LumB | European | TCGA.BH.A204.01A.11R.A157.07 |
| TCGA-BH-A204 | 80 | female | White | Solid Tissue Normal | postmenopausal | IDC | not evaluated | not evaluated | not evaluated | NA | NA | dead | 6.94 | LumB | European | TCGA.BH.A204.11A.53R.A157.07 |
| TCGA-AR-A0U2 | 47 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | metastasis | bone|liver | dead | 6.98 | LumB | European | TCGA.AR.A0U2.01A.11R.A109.07 |
| TCGA-B6-A0IN | 45 | female | White | Primary solid Tumor | indeterminate | IDC with mucinous features | positive | negative | not evaluated | metastasis | bone|brain | dead | 7.04 | NA | European | TCGA.B6.A0IN.01A.11R.A034.07 |
| TCGA-BH-A1F5 | 62 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | dead | 7.43 | NA | European | TCGA.BH.A1F5.01A.12R.A13Q.07 |
| TCGA-BH-A18K | 46 | female | White | Primary solid Tumor | not available | IDC | positive | positive | negative | NA | NA | dead | 7.56 | LumA | European | TCGA.BH.A18K.01A.11R.A12D.07 |
| TCGA-BH-A18K | 46 | female | White | Solid Tissue Normal | not available | IDC | positive | positive | negative | NA | NA | dead | 7.56 | LumA | European | TCGA.BH.A18K.11A.13R.A12D.07 |
| TCGA-BH-A1EO | 68 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC features | positive | positive | negative | NA | NA | dead | 7.66 | NA | European | TCGA.BH.A1EO.01A.11R.A137.07 |
| TCGA-BH-A1EO | 68 | female | White | Solid Tissue Normal | postmenopausal | IDC/ILC features | positive | positive | negative | NA | NA | dead | 7.66 | NA | European | TCGA.BH.A1EO.11A.31R.A137.07 |
| TCGA-AR-A256 | 45 | female | White | Primary solid Tumor | premenopausal | IDC | negative | negative | negative | locoregional disease | NA | dead | 7.81 | Basal | European | TCGA.AR.A256.01A.11R.A169.07 |
| TCGA-B6-A0IH | 81 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | NA | NA | dead | 8.12 | LumA | European | TCGA.B6.A0IH.01A.11R.A115.07 |
| TCGA-B6-A0WS | 58 | female | Black or African American | Primary solid Tumor | indeterminate | IDC | positive | positive | not evaluated | NA | NA | dead | 8.12 | LumA | African_admix | TCGA.B6.A0WS.01A.11R.A115.07 |
| TCGA-BH-A1F6 | 51 | female | White | Primary solid Tumor | not available | IDC | negative | negative | negative | NA | NA | dead | 8.12 | Basal | European | TCGA.BH.A1F6.01A.11R.A13Q.07 |
| TCGA-BH-A1F6 | 51 | female | White | Solid Tissue Normal | not available | IDC | negative | negative | negative | NA | NA | dead | 8.12 | Basal | European | TCGA.BH.A1F6.11B.94R.A13Q.07 |
| TCGA-B6-A0RS | 38 | female | White | Primary solid Tumor | indeterminate | IDC | negative | negative | not evaluated | new primary | contralateral | dead | 8.39 | Her2 | European | TCGA.B6.A0RS.01A.11R.A084.07 |
| TCGA-B6-A0RP | 73 | female | White | Primary solid Tumor | postmenopausal | IDC/ILC | positive | positive | not evaluated | metastasis | bone | dead | 8.56 | NA | European | TCGA.B6.A0RP.01A.21R.A084.07 |
| TCGA-B6-A0WY | 40 | female | White | Primary solid Tumor | premenopausal | IDC | positive | negative | not evaluated | metastasis | bone | dead | 9.48 | LumA | European | TCGA.B6.A0WY.01A.11R.A109.07 |
| TCGA-BH-A1ES | 35 | female | White | Primary solid Tumor | premenopausal | IDC | positive | positive | negative | NA | NA | dead | 9.48 | NA | European | TCGA.BH.A1ES.01A.11R.A137.07 |
| TCGA-BH-A1FC | 78 | female | Black or African American | Primary solid Tumor | postmenopausal | medullary carcinoma | negative | negative | negative | NA | NA | dead | 9.51 | Basal | African | TCGA.BH.A1FC.01A.11R.A13Q.07 |
| TCGA-BH-A1FC | 78 | female | Black or African American | Solid Tissue Normal | postmenopausal | medullary carcinoma | negative | negative | negative | NA | NA | dead | 9.51 | Basal | African | TCGA.BH.A1FC.11A.32R.A13Q.07 |
| TCGA-BH-A1FB | 60 | female | White | Primary solid Tumor | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 10.05 | NA | European | TCGA.BH.A1FB.01A.11R.A13Q.07 |
| TCGA-BH-A1FB | 60 | female | White | Solid Tissue Normal | postmenopausal | IDC | positive | positive | negative | NA | NA | dead | 10.05 | NA | European | TCGA.BH.A1FB.11A.33R.A13Q.07 |
| TCGA-B6-A0IB | 64 | female | White | Primary solid Tumor | indeterminate | IDC | positive | positive | not evaluated | metastasis | skin>lung|bone|liver | dead | 10.79 | LumB | European | TCGA.B6.A0IB.01A.11R.A034.07 |
| TCGA-B6-A0X0 | 54 | female | White | Primary solid Tumor | indeterminate | cribiform | positive | positive | not evaluated | NA | NA | dead | 10.8 | NA | European | TCGA.B6.A0X0.01A.21R.A115.07 |
| TCGA-BH-A209 | 77 | female | Black or African American | Primary solid Tumor | postmenopausal | medullary carcinoma | positive | positive | not evaluated | NA | NA | dead | 10.84 | LumB | African | TCGA.BH.A209.01A.11R.A157.07 |
| TCGA-BH-A209 | 77 | female | Black or African American | Solid Tissue Normal | postmenopausal | medullary carcinoma | positive | positive | not evaluated | NA | NA | dead | 10.84 | LumB | African | TCGA.BH.A209.11A.42R.A157.07 |
| TCGA-B6-A0RQ | 68 | female | White | Primary solid Tumor | postmenopausal | ILC | positive | positive | not evaluated | NA | NA | dead | 11.68 | Normal | European | TCGA.B6.A0RQ.01A.11R.A115.07 |
| TCGA-B6-A0IG | 50 | female | White | Primary solid Tumor | indeterminate | IDC | positive | positive | not evaluated | NA | NA | dead | 12.2 | LumA | European | TCGA.B6.A0IG.01A.11R.A034.07 |
There are patients available from the BCN Tissue Bank that match the selected/a subset of the criteria. Explore the data available for these patients using our Sample Finder
Overview
Patient Statistics
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Survival Status
Age at Diagnosis
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Menopausal Status
Tumour Statistics
ER Status
PR Status
HER2 Status
Cohort Summary
Drug Prediction
Cancer Genome Interpreter (CGI) help
| Gene | Protein Alteration | Alteration Match | Drug | Effect | Tumour | Evidence |
|---|---|---|---|---|---|---|
| BRCA1 | Q934* | Complete Match | Chemotherapy (PARP inhibitor;Chemotherapy) | Responsive | OV | Early trials |
| BRCA1 | Q934* | Complete Match | PARP inhibitor | Responsive | BRCA | Early trials |
| BRCA1 | Q934* | Complete Match | PARP inhibitor;Chemotherapy | Responsive | OV | Early trials |
| BRCA1 | Q934* | Complete Match | Rucaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | Q934* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | Q934* | Complete Match | WEE1 inhibitor | Responsive | CANCER | Case report |
| BRCA1 | Q934* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | OV | Late trials |
| BRCA1 | Q934* | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| BRCA1 | Q934* | Complete Match | Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | Q934* | Complete Match | PARP inhibitor | Responsive | PA | Case report |
| BRCA1 | Q934* | Complete Match | Olaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | Q934* | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q944* | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q944* | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q944* | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | Q944* | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| PIK3CA | H1047L | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | H1047L | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | H1047L | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | H1047L | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | H1047L | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | H1047L | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | H1047L | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | H1047L | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | H1047L | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047L | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | H1047L | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047L | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | H1047L | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | H1047L | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| CDH1 | Q23* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| ROS1 | P194S | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | P194S | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | P194S | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | P194S | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | P194S | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| CDH1 | R63* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| NF1 | R366* | Different Mutation | Vemurafenib (BRAF inhibitor) | Resistant | CM | Pre-clinical |
| NF1 | R366* | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | HNC | Case report |
| NF1 | R366* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | R366* | Complete Match | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | R366* | Complete Match | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Complete Match | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Complete Match | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | R366* | Complete Match | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | R366* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | NF | Late trials |
| NF1 | R366* | Complete Match | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | R366* | Complete Match | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Complete Match | Nilotinib (BCR-ABL inhibitor) | Responsive | MPN, PLEN | Pre-clinical |
| NF1 | R366* | Complete Match | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | HNC, SG | Case report |
| NF1 | R366* | Complete Match | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | R366* | Complete Match | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | R366* | Complete Match | MEK inhibitor | Responsive | LK, G | Pre-clinical |
| NF1 | R366* | Complete Match | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | R366* | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | R366* | Complete Match | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Complete Match | MTOR inhibitor | Responsive | LK, G, MPN | Pre-clinical |
| NF1 | R366* | Complete Match | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | R366* | Complete Match | Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) | Responsive | HC | Case report |
| NF1 | R366* | Complete Match | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | R366* | Complete Match | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | R366* | Complete Match | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | R366* | Complete Match | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | R366* | Complete Match | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | R366* | Complete Match | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | R366* | Complete Match | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | R366* | Complete Match | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | R366* | Complete Match | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Complete Match | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | R366* | Complete Match | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | R366* | Complete Match | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | R366* | Different Alteration | MTOR inhibitor | Responsive | MPN, G, LK | Pre-clinical |
| NF1 | R366* | Different Alteration | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | R366* | Different Alteration | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | R366* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | R366* | Different Alteration | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Different Alteration | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | R366* | Different Alteration | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | R366* | Different Alteration | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | R366* | Different Alteration | MEK inhibitor | Responsive | G, LK | Pre-clinical |
| NF1 | R366* | Different Alteration | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | R366* | Different Alteration | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Different Alteration | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | R366* | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | R366* | Different Alteration | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Different Alteration | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | R366* | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | R366* | Different Alteration | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | SG, HNC | Case report |
| NF1 | R366* | Different Alteration | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | R366* | Different Alteration | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | R366* | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | R366* | Different Alteration | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | R366* | Different Alteration | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | R366* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | R366* | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | PLEN, MPN | Pre-clinical |
| NF1 | R366* | Different Alteration | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | R366* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | R366* | Different Alteration | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Different Alteration | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | R366* | Different Alteration | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | R366* | Different Alteration | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | R366* | Different Alteration | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| PIK3CA | E542K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E542K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E542K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E542K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E542K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E542K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E542K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E542K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E542K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E542K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E542K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E542K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E542K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E542K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| ARID1A | Q479* | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q479* | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q479* | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | Q479* | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| ERBB2 | V777L | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | V777L | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | V777L | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, BRCA, GEJA | FDA guidelines |
| ERBB2 | V777L | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | V777L | Different Alteration | MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) | Responsive | SOLID | Early trials |
| ERBB2 | V777L | Complete Match | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | V777L | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | V777L | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER, BRCA | Pre-clinical |
| ERBB2 | V777L | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | V777L | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | V777L | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Case report |
| ERBB2 | V777L | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA, LUAD | Case report |
| ERBB2 | V777L | Different Mutation | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | L | Early trials |
| ERBB2 | V777L | Different Mutation | Neratinib (ERBB2 inhibitor) | Resistant | BRCA | Case report |
| ERBB2 | V777L | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | V777L | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Case report |
| ERBB2 | V777L | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | V777L | Different Mutation | Lapatinib (ERBB2 inhibitor) | Resistant | BRCA | Pre-clinical |
| ERBB2 | V777L | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB2 | V777L | Complete Match | Temsirolimus (MTOR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V777L | Complete Match | Dacomitinib (Pan ERBB inhibitor) | Responsive | NSCLC | Early trials |
| ERBB2 | V777L | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V777L | Different Mutation | ERBB2 inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | V777L | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V777L | Different Mutation | ERBB2 mAb inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | V777L | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V777L | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V777L | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V777L | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | V777L | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | V777L | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | COREAD | Late trials |
| ERBB2 | V777L | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | OV | Early trials |
| ERBB2 | V777L | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB2 | V777L | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | COREAD | Case report |
| ERBB2 | V777L | Different Alteration | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | V777L | Different Alteration | Osimertinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | V777L | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | V777L | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| ERBB2 | V777L | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BT | Early trials |
| ERBB2 | V777L | Different Alteration | Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) | Responsive | BRCA | Early trials |
| ERBB2 | V777L | Different Alteration | HER2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | V777L | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | V777L | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | ST | Early trials |
| ERBB2 | V777L | Different Alteration | Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| ERBB2 | V777L | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, GEJA | FDA guidelines |
| ERBB2 | V777L | Different Alteration | ERBB2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | V777L | Different Alteration | Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | V777L | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | HNC | Case report |
| ERBB2 | V777L | Different Alteration | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | V777L | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | No Responsive | ED | Early trials |
| ERBB2 | V777L | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | ED | Pre-clinical |
| ERBB2 | V777L | Different Alteration | Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) | Responsive | ST | Early trials |
| ERBB2 | V777L | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | ST | Case report |
| ERBB2 | V777L | Different Alteration | EGFR inhibitor | Resistant | LUAD | Pre-clinical |
| CDH1 | splice_donor_variant | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| RB1 | S829* | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | S829* | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | S829* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | S829* | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | S829* | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | S829* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | S829* | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| TP53 | R175H | Complete Match | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R175H | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R175H | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R175H | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R175H | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R175H | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R175H | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R175H | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R175H | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R175H | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R175H | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R175H | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R175H | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R175H | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R175H | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (E726K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| AKT3 | L151F | Different Alteration | ATP competitive AKT inhibitor | Responsive | BRCA | Pre-clinical |
| ARID1A | Q393* | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q393* | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q393* | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | Q393* | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| ERCC4 | R8* | Complete Match | Cisplatin (Chemotherapy) | Responsive | OV | Pre-clinical |
| NF1 | Q535* | Different Mutation | Vemurafenib (BRAF inhibitor) | Resistant | CM | Pre-clinical |
| NF1 | Q535* | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | HNC | Case report |
| NF1 | Q535* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q535* | Complete Match | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | Q535* | Complete Match | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Complete Match | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Complete Match | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | Q535* | Complete Match | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | Q535* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | NF | Late trials |
| NF1 | Q535* | Complete Match | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | Q535* | Complete Match | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Complete Match | Nilotinib (BCR-ABL inhibitor) | Responsive | MPN, PLEN | Pre-clinical |
| NF1 | Q535* | Complete Match | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | HNC, SG | Case report |
| NF1 | Q535* | Complete Match | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q535* | Complete Match | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | Q535* | Complete Match | MEK inhibitor | Responsive | LK, G | Pre-clinical |
| NF1 | Q535* | Complete Match | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | Q535* | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q535* | Complete Match | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Complete Match | MTOR inhibitor | Responsive | LK, G, MPN | Pre-clinical |
| NF1 | Q535* | Complete Match | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q535* | Complete Match | Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) | Responsive | HC | Case report |
| NF1 | Q535* | Complete Match | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q535* | Complete Match | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q535* | Complete Match | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | Q535* | Complete Match | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | Q535* | Complete Match | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | Q535* | Complete Match | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | Q535* | Complete Match | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q535* | Complete Match | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q535* | Complete Match | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Complete Match | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | Q535* | Complete Match | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q535* | Complete Match | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | Q535* | Different Alteration | MTOR inhibitor | Responsive | MPN, G, LK | Pre-clinical |
| NF1 | Q535* | Different Alteration | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | Q535* | Different Alteration | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q535* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | Q535* | Different Alteration | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Different Alteration | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | Q535* | Different Alteration | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q535* | Different Alteration | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | Q535* | Different Alteration | MEK inhibitor | Responsive | G, LK | Pre-clinical |
| NF1 | Q535* | Different Alteration | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | Q535* | Different Alteration | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Different Alteration | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q535* | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q535* | Different Alteration | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Different Alteration | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | Q535* | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q535* | Different Alteration | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | SG, HNC | Case report |
| NF1 | Q535* | Different Alteration | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | Q535* | Different Alteration | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q535* | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q535* | Different Alteration | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | Q535* | Different Alteration | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q535* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q535* | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | PLEN, MPN | Pre-clinical |
| NF1 | Q535* | Different Alteration | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | Q535* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | Q535* | Different Alteration | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Different Alteration | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | Q535* | Different Alteration | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | Q535* | Different Alteration | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q535* | Different Alteration | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| ESR1 | Q17H | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| JAK2 | R133P | Different Alteration | Ruxolitinib (JAK inhibitor) | Responsive | ALL | Pre-clinical |
| BRAF | S112C | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | CM, LUAD, PRAD | Pre-clinical |
| BRAF | S112C | Different Alteration | MEK inhibitor | Responsive | LUAD, CM, PRAD | Pre-clinical |
| BRAF | S112C | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | OV | Case report |
| BRAF | S112C | Different Alteration | BRAF inhibitor;MEK inhibitor | Responsive | LUAD | Case report |
| SETD2 | S461* | Complete Match | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| SETD2 | S461* | Different Alteration | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E542K), PIK3CA MUT (R88Q | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| PML | intron_variant | Different Alteration | Volasertib (PLK1 inhibitor) | Responsive | AML | Early trials |
| PML | intron_variant | Different Alteration | Tretinoin (Retinoid) | Responsive | APML | FDA guidelines |
| PML | intron_variant | Different Alteration | Tretinoin;Arsenic Trioxide (Retinoid;Chemotherapy) | Responsive | AML | FDA guidelines |
| NF1 | W571* | Different Mutation | Vemurafenib (BRAF inhibitor) | Resistant | CM | Pre-clinical |
| NF1 | W571* | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | HNC | Case report |
| NF1 | W571* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W571* | Complete Match | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | W571* | Complete Match | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Complete Match | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Complete Match | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | W571* | Complete Match | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | W571* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | NF | Late trials |
| NF1 | W571* | Complete Match | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | W571* | Complete Match | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Complete Match | Nilotinib (BCR-ABL inhibitor) | Responsive | MPN, PLEN | Pre-clinical |
| NF1 | W571* | Complete Match | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | HNC, SG | Case report |
| NF1 | W571* | Complete Match | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | W571* | Complete Match | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | W571* | Complete Match | MEK inhibitor | Responsive | LK, G | Pre-clinical |
| NF1 | W571* | Complete Match | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | W571* | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W571* | Complete Match | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Complete Match | MTOR inhibitor | Responsive | LK, G, MPN | Pre-clinical |
| NF1 | W571* | Complete Match | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | W571* | Complete Match | Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) | Responsive | HC | Case report |
| NF1 | W571* | Complete Match | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | W571* | Complete Match | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | W571* | Complete Match | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | W571* | Complete Match | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | W571* | Complete Match | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | W571* | Complete Match | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | W571* | Complete Match | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | W571* | Complete Match | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W571* | Complete Match | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Complete Match | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | W571* | Complete Match | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | W571* | Complete Match | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | W571* | Different Alteration | MTOR inhibitor | Responsive | MPN, G, LK | Pre-clinical |
| NF1 | W571* | Different Alteration | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | W571* | Different Alteration | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | W571* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | W571* | Different Alteration | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Different Alteration | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | W571* | Different Alteration | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | W571* | Different Alteration | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | W571* | Different Alteration | MEK inhibitor | Responsive | G, LK | Pre-clinical |
| NF1 | W571* | Different Alteration | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | W571* | Different Alteration | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Different Alteration | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | W571* | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | W571* | Different Alteration | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Different Alteration | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | W571* | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W571* | Different Alteration | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | SG, HNC | Case report |
| NF1 | W571* | Different Alteration | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | W571* | Different Alteration | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | W571* | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W571* | Different Alteration | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | W571* | Different Alteration | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | W571* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W571* | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | PLEN, MPN | Pre-clinical |
| NF1 | W571* | Different Alteration | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | W571* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | W571* | Different Alteration | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Different Alteration | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | W571* | Different Alteration | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | W571* | Different Alteration | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W571* | Different Alteration | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| TP53 | V272M | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | V272M | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | V272M | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | V272M | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | V272M | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | V272M | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | V272M | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V272M | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V272M | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | V272M | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | V272M | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | V272M | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V272M | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | V272M | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V272M | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | H1047R | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | H1047R | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | H1047R | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | H1047R | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | H1047R | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | H1047R | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | H1047R | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | H1047R | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | H1047R | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | H1047R | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | H1047R | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | H1047R | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | M133K | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | M133K | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | M133K | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | M133K | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | M133K | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | M133K | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | M133K | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | M133K | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | M133K | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | M133K | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | M133K | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | M133K | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | M133K | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | M133K | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | M133K | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | G118D | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | G118D | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | G118D | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | G118D | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | G118D | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | G118D | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | G118D | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | G118D | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | G118D | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | G118D | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | G118D | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | G118D | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | G118D | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | G118D | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| KMT2A | V3015I | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | V3015I | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | V3015I | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | V3015I | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | V3015I | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | V3015I | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E542K), PIK3CA MUT (M1004I | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | R196* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R196* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R196* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R196* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R196* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R196* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R196* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R196* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R196* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R196* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R196* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R196* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R196* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R196* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R196* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| AKT3 | L274L | Different Alteration | ATP competitive AKT inhibitor | Responsive | BRCA | Pre-clinical |
| PIK3CA | G1049R | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | G1049R | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | G1049R | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | G1049R | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | G1049R | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | G1049R | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | G1049R | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | G1049R | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | G1049R | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | G1049R | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | G1049R | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | G1049R | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | G1049R | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | G1049R | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| CHEK2 | Q69* | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| CHEK2 | Q69* | Different Alteration | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| PTPRD | L1535* | Complete Match | IGF1R inhibitor | Responsive | S | Case report |
| TP53 | S183* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | S183* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | S183* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | S183* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | S183* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | S183* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | S183* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | S183* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | S183* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | S183* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | S183* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | S183* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | S183* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | S183* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | S183* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R273L | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R273L | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R273L | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R273L | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R273L | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R273L | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R273L | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R273L | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R273L | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R273L | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R273L | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R273L | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R273L | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R273L | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R273L | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| BRCA1 | splice_donor_variant | Complete Match | Chemotherapy (PARP inhibitor;Chemotherapy) | Responsive | OV | Early trials |
| BRCA1 | splice_donor_variant | Complete Match | PARP inhibitor | Responsive | BRCA | Early trials |
| BRCA1 | splice_donor_variant | Complete Match | PARP inhibitor;Chemotherapy | Responsive | OV | Early trials |
| BRCA1 | splice_donor_variant | Complete Match | Rucaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | splice_donor_variant | Complete Match | Platinum Agent (Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | splice_donor_variant | Complete Match | WEE1 inhibitor | Responsive | CANCER | Case report |
| BRCA1 | splice_donor_variant | Complete Match | Platinum Agent (Chemotherapy) | Responsive | OV | Late trials |
| BRCA1 | splice_donor_variant | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| BRCA1 | splice_donor_variant | Complete Match | Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | splice_donor_variant | Complete Match | PARP inhibitor | Responsive | PA | Case report |
| BRCA1 | splice_donor_variant | Complete Match | Olaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | splice_donor_variant | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| TP53 | Y220C | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Y220C | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Y220C | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Y220C | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Y220C | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Y220C | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Y220C | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y220C | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y220C | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Y220C | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Y220C | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Y220C | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y220C | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Y220C | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y220C | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NTRK1 | L196M | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Case report |
| NTRK1 | L196M | Different Alteration | Pan-TKR inhibitor | Responsive | CANCER | Early trials |
| NTRK1 | L196M | Different Alteration | Pan-TK inhibitor | Responsive | LUAD | Pre-clinical |
| NTRK1 | L196M | Different Alteration | Pan-TK inhibitor | Responsive | COREAD | Case report |
| BRD4 | 3-UTRSNV | Different Alteration | BET inhibitor | Responsive | NMC | Case report |
| FGFR2 | V122M | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | V122M | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| TP53 | R273H), TP53 MUT (D208G | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R273H), TP53 MUT (D208G | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R273H), TP53 MUT (D208G | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R273H), TP53 MUT (D208G | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R273H), TP53 MUT (D208G | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R273H), TP53 MUT (D208G | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R273H), TP53 MUT (D208G | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R273H), TP53 MUT (D208G | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R273H), TP53 MUT (D208G | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R273H), TP53 MUT (D208G | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R273H), TP53 MUT (D208G | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R273H), TP53 MUT (D208G | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R273H), TP53 MUT (D208G | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R273H), TP53 MUT (D208G | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R273H), TP53 MUT (D208G | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| EGFR | L792L | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | L792L | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| PIK3CA | H1047Y | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | H1047Y | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | H1047Y | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | H1047Y | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | H1047Y | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | H1047Y | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | H1047Y | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | H1047Y | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | H1047Y | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047Y | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | H1047Y | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047Y | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | H1047Y | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | H1047Y | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| PIK3CA | R88Q | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | R88Q | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | R88Q | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | R88Q | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | R88Q | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | R88Q | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | R88Q | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | R88Q | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | R88Q | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | R88Q | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | R88Q | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | R88Q | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | R88Q | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | R88Q | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| PTEN | R130* | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | R130* | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | R130* | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | R130* | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | R130* | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | R130* | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | R130* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | R130* | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | R130* | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | R130* | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | R130* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | R130* | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | R130* | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | R130* | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | R130* | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | R130* | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | R130* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | R130* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | R130* | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | R130* | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | R130* | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | R130* | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | R130* | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | R130* | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | R130* | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| CDH1 | G278* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| PIK3CA | E545K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E545K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E545K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E545K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E545K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E545K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E545K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E545K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E545K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E545K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E545K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E545K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | Q331* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Q331* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Q331* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Q331* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Q331* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Q331* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Q331* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q331* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q331* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Q331* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Q331* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Q331* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q331* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Q331* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q331* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R273C | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R273C | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R273C | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R273C | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R273C | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R273C | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R273C | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R273C | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R273C | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R273C | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R273C | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R273C | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R273C | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R273C | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R273C | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| CDH1 | Q511* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| BRCA2 | Y3308* | Complete Match | PD1 Ab inhibitor | Responsive | CM | Case report |
| BRCA2 | Y3308* | Complete Match | Olaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA2 | Y3308* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | OV | Late trials |
| BRCA2 | Y3308* | Complete Match | Chemotherapy (PARP inhibitor;Chemotherapy) | Responsive | OV | Early trials |
| BRCA2 | Y3308* | Complete Match | PARP inhibitor;Chemotherapy | Responsive | OV | Early trials |
| BRCA2 | Y3308* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | PA | Case report |
| BRCA2 | Y3308* | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| BRCA2 | Y3308* | Complete Match | Rucaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA2 | Y3308* | Complete Match | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| BRCA2 | Y3308* | Complete Match | Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA2 | Y3308* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA2 | Y3308* | Complete Match | PARP inhibitor | Responsive | BRCA | Early trials |
| BRCA2 | Y3308* | Different Alteration | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| BRCA2 | Y3308* | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| AKT3 | G265R | Different Alteration | ATP competitive AKT inhibitor | Responsive | BRCA | Pre-clinical |
| BCR | T634T | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| BCR | T634T | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| BCR | T634T | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | T634T | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | T634T | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| BCR | T634T | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| STAG2 | G540* | Complete Match | PARP inhibitor | Responsive | G | Pre-clinical |
| TP53 | G199V | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | G199V | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | G199V | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | G199V | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | G199V | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | G199V | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | G199V | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G199V | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G199V | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | G199V | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | G199V | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | G199V | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G199V | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | G199V | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G199V | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| RB1 | L206* | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | L206* | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | L206* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | L206* | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | L206* | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | L206* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | L206* | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| PIK3CA | N345K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | N345K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | N345K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | N345K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | N345K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | N345K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | N345K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | N345K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | N345K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | N345K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | N345K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | N345K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | N345K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | N345K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| KMT2A | S2872L | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | S2872L | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | S2872L | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | S2872L | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | S2872L | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | S2872L | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| BCR | intron_variant | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| BCR | intron_variant | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| BCR | intron_variant | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | intron_variant | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | intron_variant | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| BCR | intron_variant | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| TP53 | Y234C | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Y234C | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Y234C | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Y234C | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Y234C | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Y234C | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Y234C | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y234C | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y234C | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Y234C | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Y234C | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Y234C | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y234C | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Y234C | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y234C | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| RNF43 | S425* | Complete Match | Porcupine inhibitor | Responsive | COREAD | Case report |
| NOTCH2 | G2381G | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | L824L | Different Alteration | IGF1R inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | L824L | Different Alteration | PI3K pathway inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | L824L | Different Alteration | Midostaurin (Pan-TK inhibitor) | Responsive | BRCA | Pre-clinical |
| SF3B1 | K700E | Complete Match | Spliceosome inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R342* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R342* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R342* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R342* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R342* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R342* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R342* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R342* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R342* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R342* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R342* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R342* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R342* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R342* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R342* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| KMT2A | K3048T | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | K3048T | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | K3048T | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | K3048T | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | K3048T | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | K3048T | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| ATM | R3047* | Different Mutation | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ATM | R3047* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| ATM | R3047* | Complete Match | Olaparib (PARP inhibitor) | Responsive | ST, PRAD | Early trials |
| ATM | R3047* | Complete Match | PARP inhibitor | Responsive | ST | Early trials |
| ATM | R3047* | Complete Match | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | R3047* | Complete Match | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | R3047* | Complete Match | Temozolomide (Chemotherapy) | Responsive | G | Pre-clinical |
| ATM | R3047* | Complete Match | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | R3047* | Different Alteration | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | R3047* | Different Alteration | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | R3047* | Different Alteration | PARP inhibitor | Responsive | ST | Early trials |
| ATM | R3047* | Different Alteration | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | R3047* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| FBXW7 | R479Q | Complete Match | Steroid | Responsive | ALL | Late trials |
| FBXW7 | R479Q | Complete Match | Tubulin inhibitor | Resistant | CANCER | Pre-clinical |
| FBXW7 | R479Q | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | COREAD | Pre-clinical |
| FBXW7 | R479Q | Different Alteration | Tubulin inhibitor | Resistant | CANCER | Pre-clinical |
| BRCA2 | L2926* | Complete Match | PD1 Ab inhibitor | Responsive | CM | Case report |
| BRCA2 | L2926* | Complete Match | Olaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA2 | L2926* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | OV | Late trials |
| BRCA2 | L2926* | Complete Match | Chemotherapy (PARP inhibitor;Chemotherapy) | Responsive | OV | Early trials |
| BRCA2 | L2926* | Complete Match | PARP inhibitor;Chemotherapy | Responsive | OV | Early trials |
| BRCA2 | L2926* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | PA | Case report |
| BRCA2 | L2926* | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| BRCA2 | L2926* | Complete Match | Rucaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA2 | L2926* | Complete Match | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| BRCA2 | L2926* | Complete Match | Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA2 | L2926* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA2 | L2926* | Complete Match | PARP inhibitor | Responsive | BRCA | Early trials |
| BRCA2 | L2926* | Different Alteration | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| BRCA2 | L2926* | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| SMARCA4 | E1611* | Complete Match | EZH2 inhibitor | Responsive | OVRT | Case report |
| SMARCA4 | E1611* | Complete Match | AURKA inhibitor | Responsive | NSCLC | Pre-clinical |
| SMARCA4 | E1611* | Complete Match | EZH2 inhibitor | Responsive | OV | Case report |
| SMARCA4 | E1611* | Different Alteration | EZH2 inhibitor | Responsive | OVRT | Case report |
| SMARCA4 | E1611* | Different Alteration | EZH2 inhibitor | Responsive | OV | Case report |
| PDGFRA | R981P | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | MDPS, MDS, ECL, HES | FDA guidelines |
| CDH1 | splice_acceptor_variant | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| PIK3CA | Q546R | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | Q546R | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | Q546R | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | Q546R | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | Q546R | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | Q546R | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | Q546R | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | Q546R | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | Q546R | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | Q546R | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | Q546R | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | Q546R | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | Q546R | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | Q546R | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| ERBB2 | L755W | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | L755W | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | L755W | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, BRCA, GEJA | FDA guidelines |
| ERBB2 | L755W | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | L755W | Different Alteration | MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) | Responsive | SOLID | Early trials |
| ERBB2 | L755W | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | L755W | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | L755W | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER, BRCA | Pre-clinical |
| ERBB2 | L755W | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | L755W | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | L755W | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Case report |
| ERBB2 | L755W | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA, LUAD | Case report |
| ERBB2 | L755W | Different Mutation | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | L | Early trials |
| ERBB2 | L755W | Different Mutation | Neratinib (ERBB2 inhibitor) | Resistant | BRCA | Case report |
| ERBB2 | L755W | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | L755W | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Case report |
| ERBB2 | L755W | Different Mutation | Lapatinib (ERBB2 inhibitor) | Resistant | BRCA | Pre-clinical |
| ERBB2 | L755W | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB2 | L755W | Complete Match | Temsirolimus (MTOR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755W | Complete Match | Dacomitinib (Pan ERBB inhibitor) | Responsive | NSCLC | Early trials |
| ERBB2 | L755W | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755W | Different Mutation | ERBB2 inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | L755W | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755W | Different Mutation | ERBB2 mAb inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | L755W | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755W | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755W | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755W | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | L755W | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | L755W | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | COREAD | Late trials |
| ERBB2 | L755W | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | OV | Early trials |
| ERBB2 | L755W | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB2 | L755W | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | COREAD | Case report |
| ERBB2 | L755W | Different Alteration | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | L755W | Different Alteration | Osimertinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | L755W | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | L755W | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| ERBB2 | L755W | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BT | Early trials |
| ERBB2 | L755W | Different Alteration | Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) | Responsive | BRCA | Early trials |
| ERBB2 | L755W | Different Alteration | HER2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | L755W | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | L755W | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | ST | Early trials |
| ERBB2 | L755W | Different Alteration | Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| ERBB2 | L755W | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, GEJA | FDA guidelines |
| ERBB2 | L755W | Different Alteration | ERBB2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | L755W | Different Alteration | Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | L755W | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | HNC | Case report |
| ERBB2 | L755W | Different Alteration | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | L755W | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | No Responsive | ED | Early trials |
| ERBB2 | L755W | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | ED | Pre-clinical |
| ERBB2 | L755W | Different Alteration | Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) | Responsive | ST | Early trials |
| ERBB2 | L755W | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | ST | Case report |
| ERBB2 | L755W | Different Alteration | EGFR inhibitor | Resistant | LUAD | Pre-clinical |
| ERBB2 | R678Q | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | R678Q | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | R678Q | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, BRCA, GEJA | FDA guidelines |
| ERBB2 | R678Q | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | R678Q | Different Alteration | MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) | Responsive | SOLID | Early trials |
| ERBB2 | R678Q | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | R678Q | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | R678Q | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER, BRCA | Pre-clinical |
| ERBB2 | R678Q | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | R678Q | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Case report |
| ERBB2 | R678Q | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA, LUAD | Case report |
| ERBB2 | R678Q | Different Mutation | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | L | Early trials |
| ERBB2 | R678Q | Different Mutation | Neratinib (ERBB2 inhibitor) | Resistant | BRCA | Case report |
| ERBB2 | R678Q | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | R678Q | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Case report |
| ERBB2 | R678Q | Different Mutation | Lapatinib (ERBB2 inhibitor) | Resistant | BRCA | Pre-clinical |
| ERBB2 | R678Q | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB2 | R678Q | Complete Match | Temsirolimus (MTOR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | R678Q | Complete Match | Dacomitinib (Pan ERBB inhibitor) | Responsive | NSCLC | Early trials |
| ERBB2 | R678Q | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | R678Q | Different Mutation | ERBB2 inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | R678Q | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | R678Q | Different Mutation | ERBB2 mAb inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | R678Q | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | R678Q | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | R678Q | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | R678Q | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | R678Q | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | R678Q | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | COREAD | Late trials |
| ERBB2 | R678Q | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | OV | Early trials |
| ERBB2 | R678Q | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB2 | R678Q | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | COREAD | Case report |
| ERBB2 | R678Q | Different Alteration | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | R678Q | Different Alteration | Osimertinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | R678Q | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | R678Q | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| ERBB2 | R678Q | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BT | Early trials |
| ERBB2 | R678Q | Different Alteration | Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) | Responsive | BRCA | Early trials |
| ERBB2 | R678Q | Different Alteration | HER2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | R678Q | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | R678Q | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | ST | Early trials |
| ERBB2 | R678Q | Different Alteration | Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| ERBB2 | R678Q | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, GEJA | FDA guidelines |
| ERBB2 | R678Q | Different Alteration | ERBB2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | R678Q | Different Alteration | Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | R678Q | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | HNC | Case report |
| ERBB2 | R678Q | Different Alteration | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | R678Q | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | No Responsive | ED | Early trials |
| ERBB2 | R678Q | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | ED | Pre-clinical |
| ERBB2 | R678Q | Different Alteration | Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) | Responsive | ST | Early trials |
| ERBB2 | R678Q | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | ST | Case report |
| ERBB2 | R678Q | Different Alteration | EGFR inhibitor | Resistant | LUAD | Pre-clinical |
| MET | I565M | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | G | Case report |
| TP53 | P278L | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | P278L | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | P278L | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | P278L | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | P278L | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | P278L | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | P278L | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P278L | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P278L | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | P278L | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | P278L | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | P278L | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P278L | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | P278L | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P278L | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NF1 | W1048* | Different Mutation | Vemurafenib (BRAF inhibitor) | Resistant | CM | Pre-clinical |
| NF1 | W1048* | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | HNC | Case report |
| NF1 | W1048* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W1048* | Complete Match | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | W1048* | Complete Match | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Complete Match | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Complete Match | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | W1048* | Complete Match | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | W1048* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | NF | Late trials |
| NF1 | W1048* | Complete Match | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | W1048* | Complete Match | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Complete Match | Nilotinib (BCR-ABL inhibitor) | Responsive | MPN, PLEN | Pre-clinical |
| NF1 | W1048* | Complete Match | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | HNC, SG | Case report |
| NF1 | W1048* | Complete Match | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | W1048* | Complete Match | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | W1048* | Complete Match | MEK inhibitor | Responsive | LK, G | Pre-clinical |
| NF1 | W1048* | Complete Match | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | W1048* | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W1048* | Complete Match | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Complete Match | MTOR inhibitor | Responsive | LK, G, MPN | Pre-clinical |
| NF1 | W1048* | Complete Match | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | W1048* | Complete Match | Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) | Responsive | HC | Case report |
| NF1 | W1048* | Complete Match | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | W1048* | Complete Match | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | W1048* | Complete Match | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | W1048* | Complete Match | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | W1048* | Complete Match | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | W1048* | Complete Match | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | W1048* | Complete Match | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | W1048* | Complete Match | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W1048* | Complete Match | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Complete Match | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | W1048* | Complete Match | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | W1048* | Complete Match | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | W1048* | Different Alteration | MTOR inhibitor | Responsive | MPN, G, LK | Pre-clinical |
| NF1 | W1048* | Different Alteration | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | W1048* | Different Alteration | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | W1048* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | W1048* | Different Alteration | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Different Alteration | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | W1048* | Different Alteration | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | W1048* | Different Alteration | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | W1048* | Different Alteration | MEK inhibitor | Responsive | G, LK | Pre-clinical |
| NF1 | W1048* | Different Alteration | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | W1048* | Different Alteration | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Different Alteration | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | W1048* | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | W1048* | Different Alteration | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Different Alteration | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | W1048* | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W1048* | Different Alteration | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | SG, HNC | Case report |
| NF1 | W1048* | Different Alteration | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | W1048* | Different Alteration | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | W1048* | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W1048* | Different Alteration | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | W1048* | Different Alteration | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | W1048* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | W1048* | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | PLEN, MPN | Pre-clinical |
| NF1 | W1048* | Different Alteration | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | W1048* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | W1048* | Different Alteration | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Different Alteration | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | W1048* | Different Alteration | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | W1048* | Different Alteration | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | W1048* | Different Alteration | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Different Mutation | Vemurafenib (BRAF inhibitor) | Resistant | CM | Pre-clinical |
| NF1 | Q554* | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | HNC | Case report |
| NF1 | Q554* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q554* | Complete Match | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | Q554* | Complete Match | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Complete Match | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Complete Match | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | Q554* | Complete Match | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | Q554* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | NF | Late trials |
| NF1 | Q554* | Complete Match | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | Q554* | Complete Match | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Complete Match | Nilotinib (BCR-ABL inhibitor) | Responsive | MPN, PLEN | Pre-clinical |
| NF1 | Q554* | Complete Match | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | HNC, SG | Case report |
| NF1 | Q554* | Complete Match | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q554* | Complete Match | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | Q554* | Complete Match | MEK inhibitor | Responsive | LK, G | Pre-clinical |
| NF1 | Q554* | Complete Match | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | Q554* | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q554* | Complete Match | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Complete Match | MTOR inhibitor | Responsive | LK, G, MPN | Pre-clinical |
| NF1 | Q554* | Complete Match | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q554* | Complete Match | Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) | Responsive | HC | Case report |
| NF1 | Q554* | Complete Match | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q554* | Complete Match | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q554* | Complete Match | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | Q554* | Complete Match | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | Q554* | Complete Match | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | Q554* | Complete Match | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | Q554* | Complete Match | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q554* | Complete Match | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q554* | Complete Match | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Complete Match | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | Q554* | Complete Match | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q554* | Complete Match | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | Q554* | Different Alteration | MTOR inhibitor | Responsive | MPN, G, LK | Pre-clinical |
| NF1 | Q554* | Different Alteration | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | Q554* | Different Alteration | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q554* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | Q554* | Different Alteration | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Different Alteration | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | Q554* | Different Alteration | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q554* | Different Alteration | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | Q554* | Different Alteration | MEK inhibitor | Responsive | G, LK | Pre-clinical |
| NF1 | Q554* | Different Alteration | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | Q554* | Different Alteration | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Different Alteration | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q554* | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q554* | Different Alteration | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Different Alteration | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | Q554* | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q554* | Different Alteration | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | SG, HNC | Case report |
| NF1 | Q554* | Different Alteration | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | Q554* | Different Alteration | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q554* | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q554* | Different Alteration | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | Q554* | Different Alteration | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q554* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q554* | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | PLEN, MPN | Pre-clinical |
| NF1 | Q554* | Different Alteration | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | Q554* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | Q554* | Different Alteration | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Different Alteration | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | Q554* | Different Alteration | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | Q554* | Different Alteration | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q554* | Different Alteration | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| TP53 | Y163C | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Y163C | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Y163C | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Y163C | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Y163C | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Y163C | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Y163C | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y163C | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y163C | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Y163C | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Y163C | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Y163C | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y163C | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Y163C | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y163C | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | I255S | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | I255S | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | I255S | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | I255S | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | I255S | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | I255S | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | I255S | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | I255S | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | I255S | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | I255S | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | I255S | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | I255S | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | I255S | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | I255S | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | I255S | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| CDH1 | Y835* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| TP53 | E221* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | E221* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | E221* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | E221* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | E221* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | E221* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E221* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E221* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E221* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | E221* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | E221* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | E221* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E221* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | E221* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E221* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C135R | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C135R | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C135R | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C135R | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C135R | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C135R | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C135R | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C135R | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C135R | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C135R | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C135R | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C135R | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C135R | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C135R | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C135R | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ERBB4 | P920R | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| NOTCH1 | T887I | Different Alteration | Gamma secretase inhibitor | Responsive | ALL | Pre-clinical |
| NOTCH1 | T887I | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| ARID1A | splice_donor_variant | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | splice_donor_variant | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | splice_donor_variant | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | splice_donor_variant | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | I195T | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | I195T | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | I195T | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | I195T | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | I195T | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | I195T | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | I195T | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | I195T | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | I195T | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | I195T | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | I195T | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | I195T | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | I195T | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | I195T | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | I195T | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NPM1 | splice_acceptor_variant | Complete Match | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| NPM1 | splice_acceptor_variant | Complete Match | DOT1L inhibitor;MLL1 inhibitor | Responsive | AML | Pre-clinical |
| ATR | splice_acceptor_variant | Complete Match | Temozolomide (Chemotherapy) | Responsive | G | Pre-clinical |
| ATR | splice_acceptor_variant | Complete Match | Olaparib (PARP inhibitor) | Responsive | CANCER, OV | Pre-clinical |
| ATR | splice_acceptor_variant | Different Alteration | Olaparib (PARP inhibitor) | Responsive | OV, CANCER | Pre-clinical |
| KMT2A | P1367P | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | P1367P | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | P1367P | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | P1367P | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | P1367P | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | P1367P | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| TP53 | K132E | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | K132E | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | K132E | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | K132E | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | K132E | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | K132E | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | K132E | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | K132E | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | K132E | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | K132E | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | K132E | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | K132E | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | K132E | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | K132E | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | K132E | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| EGFR | D314G | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | D314G | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| RET | R330Q | Different Alteration | Nintedanib (Pan-TK inhibitor) | Responsive | LUAD | Case report |
| RET | R330Q | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Early trials |
| RET | R330Q | Different Alteration | RET inhibitor | Responsive | LUAD | Pre-clinical |
| RET | R330Q | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | R330Q | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | R330Q | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | THCA | Pre-clinical |
| RET | R330Q | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | R330Q | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | R330Q | Different Alteration | RET inhibitor | Responsive | TH | Pre-clinical |
| PIK3CA | N345T | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | N345T | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | N345T | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | N345T | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | N345T | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | N345T | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | N345T | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | N345T | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | N345T | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | N345T | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | N345T | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | N345T | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | N345T | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | N345T | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| ERBB2 | S310F | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | S310F | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | S310F | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, BRCA, GEJA | FDA guidelines |
| ERBB2 | S310F | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | S310F | Different Alteration | MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) | Responsive | SOLID | Early trials |
| ERBB2 | S310F | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | S310F | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | S310F | Complete Match | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER, BRCA | Pre-clinical |
| ERBB2 | S310F | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | S310F | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | S310F | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Case report |
| ERBB2 | S310F | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA, LUAD | Case report |
| ERBB2 | S310F | Complete Match | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | L | Early trials |
| ERBB2 | S310F | Different Mutation | Neratinib (ERBB2 inhibitor) | Resistant | BRCA | Case report |
| ERBB2 | S310F | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | S310F | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Case report |
| ERBB2 | S310F | Different Mutation | Lapatinib (ERBB2 inhibitor) | Resistant | BRCA | Pre-clinical |
| ERBB2 | S310F | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB2 | S310F | Complete Match | Temsirolimus (MTOR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | S310F | Complete Match | Dacomitinib (Pan ERBB inhibitor) | Responsive | NSCLC | Early trials |
| ERBB2 | S310F | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | S310F | Different Mutation | ERBB2 inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | S310F | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | S310F | Different Mutation | ERBB2 mAb inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | S310F | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | S310F | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | S310F | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | S310F | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | S310F | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | S310F | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | COREAD | Late trials |
| ERBB2 | S310F | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | OV | Early trials |
| ERBB2 | S310F | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB2 | S310F | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | COREAD | Case report |
| ERBB2 | S310F | Different Alteration | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | S310F | Different Alteration | Osimertinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | S310F | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | S310F | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| ERBB2 | S310F | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BT | Early trials |
| ERBB2 | S310F | Different Alteration | Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) | Responsive | BRCA | Early trials |
| ERBB2 | S310F | Different Alteration | HER2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | S310F | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | S310F | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | ST | Early trials |
| ERBB2 | S310F | Different Alteration | Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| ERBB2 | S310F | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, GEJA | FDA guidelines |
| ERBB2 | S310F | Different Alteration | ERBB2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | S310F | Different Alteration | Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | S310F | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | HNC | Case report |
| ERBB2 | S310F | Different Alteration | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | S310F | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | No Responsive | ED | Early trials |
| ERBB2 | S310F | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | ED | Pre-clinical |
| ERBB2 | S310F | Different Alteration | Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) | Responsive | ST | Early trials |
| ERBB2 | S310F | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | ST | Case report |
| ERBB2 | S310F | Different Alteration | EGFR inhibitor | Resistant | LUAD | Pre-clinical |
| TP53 | C135F | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C135F | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C135F | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C135F | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C135F | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C135F | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C135F | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C135F | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C135F | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C135F | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C135F | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C135F | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C135F | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C135F | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C135F | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ERBB3 | G284R | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | CANCER | Pre-clinical |
| ERBB3 | G284R | Complete Match | Lapatinib (ERBB2 inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB3 | G284R | Complete Match | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB3 | G284R | Complete Match | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB3 | G284R | Complete Match | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB3 | G284R | Complete Match | ERBB3 mAb inhibitor | Responsive | CANCER | Pre-clinical |
| ERBB3 | G284R | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| STAG2 | splice_acceptor_variant | Complete Match | PARP inhibitor | Responsive | G | Pre-clinical |
| BRCA1 | E720* | Complete Match | Chemotherapy (PARP inhibitor;Chemotherapy) | Responsive | OV | Early trials |
| BRCA1 | E720* | Complete Match | PARP inhibitor | Responsive | BRCA | Early trials |
| BRCA1 | E720* | Complete Match | PARP inhibitor;Chemotherapy | Responsive | OV | Early trials |
| BRCA1 | E720* | Complete Match | Rucaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | E720* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | E720* | Complete Match | WEE1 inhibitor | Responsive | CANCER | Case report |
| BRCA1 | E720* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | OV | Late trials |
| BRCA1 | E720* | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| BRCA1 | E720* | Complete Match | Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | E720* | Complete Match | PARP inhibitor | Responsive | PA | Case report |
| BRCA1 | E720* | Complete Match | Olaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | E720* | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| TP53 | R280S | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R280S | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R280S | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R280S | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R280S | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R280S | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R280S | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R280S | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R280S | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R280S | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R280S | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R280S | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R280S | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R280S | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R280S | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | splice_acceptor_variant | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | splice_acceptor_variant | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | splice_acceptor_variant | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | splice_acceptor_variant | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | splice_acceptor_variant | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | splice_acceptor_variant | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | splice_acceptor_variant | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | splice_acceptor_variant | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | splice_acceptor_variant | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | splice_acceptor_variant | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | splice_acceptor_variant | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | splice_acceptor_variant | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | splice_acceptor_variant | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | splice_acceptor_variant | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | splice_acceptor_variant | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | T155P | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | T155P | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | T155P | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | T155P | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | T155P | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | T155P | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | T155P | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | T155P | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | T155P | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | T155P | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | T155P | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | T155P | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | T155P | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | T155P | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | T155P | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| RET | V778I | Different Alteration | Nintedanib (Pan-TK inhibitor) | Responsive | LUAD | Case report |
| RET | V778I | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Early trials |
| RET | V778I | Different Alteration | RET inhibitor | Responsive | LUAD | Pre-clinical |
| RET | V778I | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | V778I | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | V778I | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | THCA | Pre-clinical |
| RET | V778I | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | V778I | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | V778I | Different Alteration | RET inhibitor | Responsive | TH | Pre-clinical |
| PTEN | I135K | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | I135K | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | I135K | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | I135K | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | I135K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | I135K | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | I135K | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | I135K | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | I135K | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | I135K | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | I135K | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | I135K | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | I135K | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | I135K | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | I135K | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | I135K | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | I135K | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | I135K | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | I135K | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | I135K | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | I135K | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | I135K | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | I135K | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | I135K | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | I135K | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| TP53 | Y220H | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Y220H | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Y220H | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Y220H | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Y220H | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Y220H | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Y220H | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y220H | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y220H | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Y220H | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Y220H | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Y220H | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y220H | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Y220H | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y220H | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C238Y | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C238Y | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C238Y | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C238Y | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C238Y | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C238Y | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C238Y | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C238Y | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C238Y | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C238Y | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C238Y | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C238Y | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C238Y | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C238Y | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C238Y | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ERBB2 | G309A | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | G309A | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | G309A | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, BRCA, GEJA | FDA guidelines |
| ERBB2 | G309A | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | G309A | Different Alteration | MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) | Responsive | SOLID | Early trials |
| ERBB2 | G309A | Complete Match | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | G309A | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | G309A | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER, BRCA | Pre-clinical |
| ERBB2 | G309A | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | G309A | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Case report |
| ERBB2 | G309A | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA, LUAD | Case report |
| ERBB2 | G309A | Different Mutation | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | L | Early trials |
| ERBB2 | G309A | Different Mutation | Neratinib (ERBB2 inhibitor) | Resistant | BRCA | Case report |
| ERBB2 | G309A | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | G309A | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Case report |
| ERBB2 | G309A | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | G309A | Different Mutation | Lapatinib (ERBB2 inhibitor) | Resistant | BRCA | Pre-clinical |
| ERBB2 | G309A | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB2 | G309A | Complete Match | Temsirolimus (MTOR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | G309A | Complete Match | Dacomitinib (Pan ERBB inhibitor) | Responsive | NSCLC | Early trials |
| ERBB2 | G309A | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | G309A | Different Mutation | ERBB2 inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | G309A | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | G309A | Different Mutation | ERBB2 mAb inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | G309A | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | G309A | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | G309A | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | G309A | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | G309A | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | G309A | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | COREAD | Late trials |
| ERBB2 | G309A | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | OV | Early trials |
| ERBB2 | G309A | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB2 | G309A | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | COREAD | Case report |
| ERBB2 | G309A | Different Alteration | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | G309A | Different Alteration | Osimertinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | G309A | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | G309A | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| ERBB2 | G309A | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BT | Early trials |
| ERBB2 | G309A | Different Alteration | Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) | Responsive | BRCA | Early trials |
| ERBB2 | G309A | Different Alteration | HER2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | G309A | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | G309A | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | ST | Early trials |
| ERBB2 | G309A | Different Alteration | Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| ERBB2 | G309A | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, GEJA | FDA guidelines |
| ERBB2 | G309A | Different Alteration | ERBB2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | G309A | Different Alteration | Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | G309A | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | HNC | Case report |
| ERBB2 | G309A | Different Alteration | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | G309A | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | No Responsive | ED | Early trials |
| ERBB2 | G309A | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | ED | Pre-clinical |
| ERBB2 | G309A | Different Alteration | Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) | Responsive | ST | Early trials |
| ERBB2 | G309A | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | ST | Case report |
| ERBB2 | G309A | Different Alteration | EGFR inhibitor | Resistant | LUAD | Pre-clinical |
| TSC2 | R1459* | Different Mutation | Temsirolimus (MTOR inhibitor) | Responsive | ED | Case report |
| TSC2 | R1459* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | RA, GCA | FDA guidelines |
| TSC2 | R1459* | Complete Match | SRC inhibitor | Responsive | LAM | Pre-clinical |
| TSC2 | R1459* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | BLCA | Early trials |
| TSC2 | R1459* | Complete Match | MTOR inhibitor | Responsive | RA | Early trials |
| TSC2 | R1459* | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | THCA | Case report |
| TSC2 | R1459* | Different Alteration | SRC inhibitor | Responsive | LAM | Pre-clinical |
| TP53 | C176F | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C176F | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C176F | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C176F | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C176F | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C176F | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C176F | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C176F | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C176F | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C176F | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C176F | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C176F | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C176F | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C176F | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C176F | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NOTCH2 | R1630G | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | R130Q | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | R130Q | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | R130Q | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | R130Q | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | R130Q | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | R130Q | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | R130Q | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | R130Q | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | R130Q | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | R130Q | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | R130Q | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | R130Q | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | R130Q | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | R130Q | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | R130Q | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | R130Q | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | R130Q | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | R130Q | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | R130Q | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | R130Q | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | R130Q | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | R130Q | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | R130Q | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | R130Q | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | R130Q | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| NOTCH2 | S1388T | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| TP53 | M237I | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | M237I | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | M237I | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | M237I | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | M237I | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | M237I | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | M237I | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | M237I | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | M237I | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | M237I | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | M237I | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | M237I | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | M237I | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | M237I | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | M237I | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | splice_donor_variant | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | splice_donor_variant | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | splice_donor_variant | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | splice_donor_variant | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | splice_donor_variant | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | splice_donor_variant | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | splice_donor_variant | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | splice_donor_variant | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | splice_donor_variant | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | splice_donor_variant | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | splice_donor_variant | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | splice_donor_variant | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | splice_donor_variant | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | splice_donor_variant | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | splice_donor_variant | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | E545K), PIK3CA MUT (E453K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E545K), PIK3CA MUT (E453K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E545K), PIK3CA MUT (E453K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | H179R | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | H179R | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | H179R | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | H179R | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | H179R | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | H179R | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | H179R | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H179R | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H179R | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | H179R | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | H179R | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | H179R | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H179R | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | H179R | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H179R | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ESR1 | K472K | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | Q52* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Q52* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Q52* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Q52* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Q52* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Q52* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Q52* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q52* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q52* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Q52* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Q52* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Q52* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q52* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Q52* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q52* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| RET | L963V | Different Alteration | Nintedanib (Pan-TK inhibitor) | Responsive | LUAD | Case report |
| RET | L963V | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Early trials |
| RET | L963V | Different Alteration | RET inhibitor | Responsive | LUAD | Pre-clinical |
| RET | L963V | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | L963V | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | L963V | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | THCA | Pre-clinical |
| RET | L963V | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | L963V | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | L963V | Different Alteration | RET inhibitor | Responsive | TH | Pre-clinical |
| EGFR | A147T | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | A147T | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| TP53 | P250L | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | P250L | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | P250L | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | P250L | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | P250L | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | P250L | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | P250L | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P250L | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P250L | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | P250L | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | P250L | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | P250L | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P250L | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | P250L | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P250L | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ESR1 | P336P | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | G279E | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | G279E | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | G279E | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | G279E | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | G279E | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | G279E | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | G279E | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G279E | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G279E | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | G279E | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | G279E | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | G279E | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G279E | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | G279E | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G279E | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ROS1 | splice_donor_variant | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | splice_donor_variant | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | splice_donor_variant | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | splice_donor_variant | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | splice_donor_variant | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| MET | G225D | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | G | Case report |
| PDGFRA | intron_variant | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | MDPS, MDS, ECL, HES | FDA guidelines |
| BRCA1 | E272* | Complete Match | Chemotherapy (PARP inhibitor;Chemotherapy) | Responsive | OV | Early trials |
| BRCA1 | E272* | Complete Match | PARP inhibitor | Responsive | BRCA | Early trials |
| BRCA1 | E272* | Complete Match | PARP inhibitor;Chemotherapy | Responsive | OV | Early trials |
| BRCA1 | E272* | Complete Match | Rucaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | E272* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | E272* | Complete Match | WEE1 inhibitor | Responsive | CANCER | Case report |
| BRCA1 | E272* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | OV | Late trials |
| BRCA1 | E272* | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| BRCA1 | E272* | Complete Match | Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | E272* | Complete Match | PARP inhibitor | Responsive | PA | Case report |
| BRCA1 | E272* | Complete Match | Olaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | E272* | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| BRD4 | K546N | Different Alteration | BET inhibitor | Responsive | NMC | Case report |
| TP53 | S215I | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | S215I | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | S215I | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | S215I | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | S215I | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | S215I | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | S215I | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | S215I | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | S215I | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | S215I | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | S215I | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | S215I | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | S215I | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | S215I | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | S215I | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | G266E | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | G266E | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | G266E | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | G266E | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | G266E | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | G266E | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | G266E | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G266E | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G266E | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | G266E | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | G266E | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | G266E | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G266E | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | G266E | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G266E | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| BRD4 | A264A | Different Alteration | BET inhibitor | Responsive | NMC | Case report |
| ABL1 | Y440H | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| ABL1 | Y440H | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | Y440H | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| ABL1 | Y440H | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | Y440H | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| ABL1 | Y440H | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| EGFR | E282K | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | E282K | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| AKT1 | E17K | Complete Match | BRAF inhibitor | Resistant | CM | Case report |
| AKT1 | E17K | Complete Match | allosteric AKT inhibitor | Responsive | CANCER | Early trials |
| AKT1 | E17K | Complete Match | non-allosteric AKT inhibitor | Responsive | CANCER | Early trials |
| AKT1 | E17K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| AKT1 | E17K | Complete Match | Temsirolimus (MTOR inhibitor) | Responsive | ED | Early trials |
| AKT1 | E17K | Complete Match | AKT inhibitor | Responsive | CANCER | Pre-clinical |
| AKT1 | E17K | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | FH | Case report |
| ERBB2 | V842I | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | V842I | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | V842I | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, BRCA, GEJA | FDA guidelines |
| ERBB2 | V842I | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | V842I | Different Alteration | MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) | Responsive | SOLID | Early trials |
| ERBB2 | V842I | Complete Match | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | V842I | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | V842I | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER, BRCA | Pre-clinical |
| ERBB2 | V842I | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | V842I | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | V842I | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Case report |
| ERBB2 | V842I | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA, LUAD | Case report |
| ERBB2 | V842I | Different Mutation | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | L | Early trials |
| ERBB2 | V842I | Different Mutation | Neratinib (ERBB2 inhibitor) | Resistant | BRCA | Case report |
| ERBB2 | V842I | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | V842I | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Case report |
| ERBB2 | V842I | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | V842I | Different Mutation | Lapatinib (ERBB2 inhibitor) | Resistant | BRCA | Pre-clinical |
| ERBB2 | V842I | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB2 | V842I | Complete Match | Temsirolimus (MTOR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V842I | Complete Match | Dacomitinib (Pan ERBB inhibitor) | Responsive | NSCLC | Early trials |
| ERBB2 | V842I | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V842I | Different Mutation | ERBB2 inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | V842I | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V842I | Different Mutation | ERBB2 mAb inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | V842I | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V842I | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V842I | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | V842I | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | V842I | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | V842I | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | COREAD | Late trials |
| ERBB2 | V842I | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | OV | Early trials |
| ERBB2 | V842I | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB2 | V842I | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | COREAD | Case report |
| ERBB2 | V842I | Different Alteration | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | V842I | Different Alteration | Osimertinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | V842I | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | V842I | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| ERBB2 | V842I | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BT | Early trials |
| ERBB2 | V842I | Different Alteration | Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) | Responsive | BRCA | Early trials |
| ERBB2 | V842I | Different Alteration | HER2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | V842I | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | V842I | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | ST | Early trials |
| ERBB2 | V842I | Different Alteration | Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| ERBB2 | V842I | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, GEJA | FDA guidelines |
| ERBB2 | V842I | Different Alteration | ERBB2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | V842I | Different Alteration | Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | V842I | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | HNC | Case report |
| ERBB2 | V842I | Different Alteration | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | V842I | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | No Responsive | ED | Early trials |
| ERBB2 | V842I | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | ED | Pre-clinical |
| ERBB2 | V842I | Different Alteration | Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) | Responsive | ST | Early trials |
| ERBB2 | V842I | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | ST | Case report |
| ERBB2 | V842I | Different Alteration | EGFR inhibitor | Resistant | LUAD | Pre-clinical |
| KMT2A | Q1195* | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | Q1195* | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | Q1195* | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | Q1195* | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | Q1195* | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | Q1195* | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| TMPRSS2 | P83P | Different Alteration | DNA-PKc inhibitor | Responsive | PRAD | Pre-clinical |
| TMPRSS2 | P83P | Different Alteration | PARP inhibitor | Responsive | PRAD | Pre-clinical |
| JAK2 | Y44* | Different Alteration | Ruxolitinib (JAK inhibitor) | Responsive | ALL | Pre-clinical |
| ROS1 | R1182S | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | R1182S | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | R1182S | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | R1182S | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | R1182S | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| FAT1 | Q1722* | Complete Match | BET inhibitor | Responsive | HNSC | Pre-clinical |
| BRCA2 | splice_donor_variant | Complete Match | PD1 Ab inhibitor | Responsive | CM | Case report |
| BRCA2 | splice_donor_variant | Complete Match | Olaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA2 | splice_donor_variant | Complete Match | Platinum Agent (Chemotherapy) | Responsive | OV | Late trials |
| BRCA2 | splice_donor_variant | Complete Match | Chemotherapy (PARP inhibitor;Chemotherapy) | Responsive | OV | Early trials |
| BRCA2 | splice_donor_variant | Complete Match | PARP inhibitor;Chemotherapy | Responsive | OV | Early trials |
| BRCA2 | splice_donor_variant | Complete Match | Platinum Agent (Chemotherapy) | Responsive | PA | Case report |
| BRCA2 | splice_donor_variant | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| BRCA2 | splice_donor_variant | Complete Match | Rucaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA2 | splice_donor_variant | Complete Match | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| BRCA2 | splice_donor_variant | Complete Match | Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA2 | splice_donor_variant | Complete Match | Platinum Agent (Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA2 | splice_donor_variant | Complete Match | PARP inhibitor | Responsive | BRCA | Early trials |
| BRCA2 | splice_donor_variant | Different Alteration | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| BRCA2 | splice_donor_variant | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| JAK2 | Y132* | Different Alteration | Ruxolitinib (JAK inhibitor) | Responsive | ALL | Pre-clinical |
| SETD2 | S470* | Complete Match | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| SETD2 | S470* | Different Alteration | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | H1047L), PIK3CA MUT (E726K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| ROS1 | E596K | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | E596K | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | E596K | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | E596K | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | E596K | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| RB1 | E864* | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | E864* | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | E864* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | E864* | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | E864* | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | E864* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | E864* | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| PIK3CA | Q546K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | Q546K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | Q546K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | Q546K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | Q546K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | Q546K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | Q546K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | Q546K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | Q546K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | Q546K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | Q546K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | Q546K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | Q546K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | Q546K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | C141Y | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C141Y | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C141Y | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C141Y | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C141Y | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C141Y | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C141Y | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C141Y | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C141Y | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C141Y | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C141Y | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C141Y | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C141Y | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C141Y | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C141Y | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| FGFR3 | H711H | Different Alteration | FGFR inhibitor | Responsive | BLCA | Case report |
| FGFR3 | H711H | Different Alteration | FGFR inhibitor | Responsive | G | Early trials |
| FGFR3 | H711H | Different Alteration | FGFR inhibitor | Responsive | NSCLC | Pre-clinical |
| TP53 | Q144* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Q144* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Q144* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Q144* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Q144* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Q144* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Q144* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q144* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q144* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Q144* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Q144* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Q144* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q144* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Q144* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q144* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| CDH1 | Q641* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| PTEN | Y46* | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | Y46* | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | Y46* | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | Y46* | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | Y46* | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | Y46* | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | Y46* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | Y46* | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | Y46* | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | Y46* | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | Y46* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | Y46* | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | Y46* | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | Y46* | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | Y46* | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | Y46* | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | Y46* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | Y46* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | Y46* | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | Y46* | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | Y46* | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | Y46* | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | Y46* | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | Y46* | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | Y46* | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| TP53 | H193R | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | H193R | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | H193R | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | H193R | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | H193R | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | H193R | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | H193R | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H193R | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H193R | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | H193R | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | H193R | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | H193R | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H193R | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | H193R | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H193R | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NTRK3 | splice_donor_variant | Different Alteration | IGF1R inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | splice_donor_variant | Different Alteration | PI3K pathway inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | splice_donor_variant | Different Alteration | Midostaurin (Pan-TK inhibitor) | Responsive | BRCA | Pre-clinical |
| AKT3 | A373G | Different Alteration | ATP competitive AKT inhibitor | Responsive | BRCA | Pre-clinical |
| PML | L726L | Different Alteration | Volasertib (PLK1 inhibitor) | Responsive | AML | Early trials |
| PML | L726L | Different Alteration | Tretinoin (Retinoid) | Responsive | APML | FDA guidelines |
| PML | L726L | Different Alteration | Tretinoin;Arsenic Trioxide (Retinoid;Chemotherapy) | Responsive | AML | FDA guidelines |
| PIK3CA | E726K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E726K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E726K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E726K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E726K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E726K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E726K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E726K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E726K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E726K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E726K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E726K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E726K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E726K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| FGFR2 | V113A | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | V113A | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| STAG2 | Q167* | Complete Match | PARP inhibitor | Responsive | G | Pre-clinical |
| KMT2A | S3380L | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | S3380L | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | S3380L | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | S3380L | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | S3380L | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | S3380L | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| NOTCH1 | F1259F | Different Alteration | Gamma secretase inhibitor | Responsive | ALL | Pre-clinical |
| NOTCH1 | F1259F | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| PDGFRA | D985N | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | MDPS, MDS, ECL, HES | FDA guidelines |
| ALK | R1209P | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | R1209P | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | R1209P | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | R1209P | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | R1209P | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | R1209P | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | R1209P | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | R1209P | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | R1209P | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | R1209P | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | R1209P | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | R1209P | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | R1209P | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | R1209P | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | R1209P | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | R1209P | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | R1209P | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | R1209P | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | R1209P | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| NTRK1 | S371F | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Case report |
| NTRK1 | S371F | Different Alteration | Pan-TKR inhibitor | Responsive | CANCER | Early trials |
| NTRK1 | S371F | Different Alteration | Pan-TK inhibitor | Responsive | LUAD | Pre-clinical |
| NTRK1 | S371F | Different Alteration | Pan-TK inhibitor | Responsive | COREAD | Case report |
| NOTCH2 | A2331S | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| ESR1 | L448L | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| EGFR | D1051N), EGFR MUT* (intron_variant | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | D1051N), EGFR MUT* (intron_variant | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| ABL1 | E588Q | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| ABL1 | E588Q | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | E588Q | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| ABL1 | E588Q | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | E588Q | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| ABL1 | E588Q | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| ROS1 | H189Y), ROS1 MUT* (3-UTRSNV | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | H189Y), ROS1 MUT* (3-UTRSNV | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | H189Y), ROS1 MUT* (3-UTRSNV | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | H189Y), ROS1 MUT* (3-UTRSNV | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | H189Y), ROS1 MUT* (3-UTRSNV | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| MET | R992T), MET MUT* (L581L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | G | Case report |
| BRAF | D449N | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | CM, LUAD, PRAD | Pre-clinical |
| BRAF | D449N | Different Alteration | MEK inhibitor | Responsive | LUAD, CM, PRAD | Pre-clinical |
| BRAF | D449N | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | OV | Case report |
| BRAF | D449N | Different Alteration | BRAF inhibitor;MEK inhibitor | Responsive | LUAD | Case report |
| ERBB4 | S184L), ERBB4 MUT* (E1144Q), ERBB4 MUT* (3-UTRSNV | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| SETD2 | S791* | Complete Match | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| SETD2 | S791* | Different Alteration | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| ERBB2 | L755S | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | L755S | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | L755S | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, BRCA, GEJA | FDA guidelines |
| ERBB2 | L755S | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | L755S | Different Alteration | MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) | Responsive | SOLID | Early trials |
| ERBB2 | L755S | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | L755S | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | L755S | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER, BRCA | Pre-clinical |
| ERBB2 | L755S | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | L755S | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | L755S | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Case report |
| ERBB2 | L755S | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA, LUAD | Case report |
| ERBB2 | L755S | Different Mutation | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | L | Early trials |
| ERBB2 | L755S | Different Mutation | Neratinib (ERBB2 inhibitor) | Resistant | BRCA | Case report |
| ERBB2 | L755S | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | L755S | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Case report |
| ERBB2 | L755S | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | L755S | Different Mutation | Lapatinib (ERBB2 inhibitor) | Resistant | BRCA | Pre-clinical |
| ERBB2 | L755S | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB2 | L755S | Complete Match | Temsirolimus (MTOR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755S | Complete Match | Dacomitinib (Pan ERBB inhibitor) | Responsive | NSCLC | Early trials |
| ERBB2 | L755S | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755S | Different Mutation | ERBB2 inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | L755S | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755S | Different Mutation | ERBB2 mAb inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | L755S | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755S | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755S | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | L755S | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | L755S | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | L755S | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | COREAD | Late trials |
| ERBB2 | L755S | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | OV | Early trials |
| ERBB2 | L755S | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB2 | L755S | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | COREAD | Case report |
| ERBB2 | L755S | Different Alteration | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | L755S | Different Alteration | Osimertinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | L755S | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | L755S | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| ERBB2 | L755S | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BT | Early trials |
| ERBB2 | L755S | Different Alteration | Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) | Responsive | BRCA | Early trials |
| ERBB2 | L755S | Different Alteration | HER2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | L755S | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | L755S | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | ST | Early trials |
| ERBB2 | L755S | Different Alteration | Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| ERBB2 | L755S | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, GEJA | FDA guidelines |
| ERBB2 | L755S | Different Alteration | ERBB2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | L755S | Different Alteration | Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | L755S | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | HNC | Case report |
| ERBB2 | L755S | Different Alteration | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | L755S | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | No Responsive | ED | Early trials |
| ERBB2 | L755S | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | ED | Pre-clinical |
| ERBB2 | L755S | Different Alteration | Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) | Responsive | ST | Early trials |
| ERBB2 | L755S | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | ST | Case report |
| ERBB2 | L755S | Different Alteration | EGFR inhibitor | Resistant | LUAD | Pre-clinical |
| FGFR2 | S588C | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | S588C | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| TP53 | M246I | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | M246I | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | M246I | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | M246I | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | M246I | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | M246I | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | M246I | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | M246I | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | M246I | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | M246I | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | M246I | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | M246I | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | M246I | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | M246I | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | M246I | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| GNAS | R201C | Complete Match | JAK inhibitor | Responsive | CANCER | Pre-clinical |
| KMT2D | L2255* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | LUSC | Pre-clinical |
| TP53 | D281Y | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | D281Y | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | D281Y | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | D281Y | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | D281Y | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | D281Y | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | D281Y | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | D281Y | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | D281Y | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | D281Y | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | D281Y | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | D281Y | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | D281Y | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | D281Y | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | D281Y | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| CDH1 | Q503* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| NTRK1 | G319D | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Case report |
| NTRK1 | G319D | Different Alteration | Pan-TKR inhibitor | Responsive | CANCER | Early trials |
| NTRK1 | G319D | Different Alteration | Pan-TK inhibitor | Responsive | LUAD | Pre-clinical |
| NTRK1 | G319D | Different Alteration | Pan-TK inhibitor | Responsive | COREAD | Case report |
| NOTCH2 | T2159T | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| RAF1 | V226D | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | PRAD | Pre-clinical |
| RAF1 | V226D | Different Alteration | Pan-RAF inhibitor | Responsive | PRAD | Pre-clinical |
| RAF1 | V226D | Different Alteration | U0126 (MEK inhibitor) | Responsive | PRAD | Pre-clinical |
| ESR1 | 3-UTRSNV | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| SF3B1 | E622Q | Different Mutation | Spliceosome inhibitor | Responsive | CANCER | Pre-clinical |
| RB1 | Y606* | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | Y606* | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | Y606* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | Y606* | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | Y606* | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | Y606* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | Y606* | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| ATM | Q2800* | Different Mutation | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ATM | Q2800* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| ATM | Q2800* | Complete Match | Olaparib (PARP inhibitor) | Responsive | ST, PRAD | Early trials |
| ATM | Q2800* | Complete Match | PARP inhibitor | Responsive | ST | Early trials |
| ATM | Q2800* | Complete Match | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | Q2800* | Complete Match | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | Q2800* | Complete Match | Temozolomide (Chemotherapy) | Responsive | G | Pre-clinical |
| ATM | Q2800* | Complete Match | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | Q2800* | Different Alteration | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | Q2800* | Different Alteration | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | Q2800* | Different Alteration | PARP inhibitor | Responsive | ST | Early trials |
| ATM | Q2800* | Different Alteration | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | Q2800* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| KMT2A | P3959P | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | P3959P | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | P3959P | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | P3959P | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | P3959P | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | P3959P | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| CDH1 | Q647* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB4 | E1205K | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| PIK3CA | E545A | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E545A | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E545A | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E545A | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E545A | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E545A | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E545A | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E545A | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E545A | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545A | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E545A | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545A | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E545A | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E545A | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| MET | A932A | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | G | Case report |
| TP53 | R342P | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R342P | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R342P | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R342P | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R342P | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R342P | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R342P | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R342P | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R342P | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R342P | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R342P | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R342P | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R342P | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R342P | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R342P | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| GATA3 | splice_acceptor_variant | Complete Match | Aromatase ihibitor | Responsive | BRCA | Pre-clinical |
| CDH1 | R74* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| ALK | N1544N | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | N1544N | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | N1544N | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | N1544N | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | N1544N | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | N1544N | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | N1544N | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | N1544N | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | N1544N | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | N1544N | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | N1544N | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | N1544N | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | N1544N | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | N1544N | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | N1544N | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | N1544N | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | N1544N | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | N1544N | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | N1544N | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| ALK | G1121D | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | G1121D | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | G1121D | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | G1121D | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | G1121D | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | G1121D | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | G1121D | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | G1121D | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | G1121D | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | G1121D | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | G1121D | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | G1121D | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | G1121D | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | G1121D | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | G1121D | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | G1121D | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | G1121D | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | G1121D | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | G1121D | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| HIF1A | R463* | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | R | Pre-clinical |
| RB1 | splice_donor_variant | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | splice_donor_variant | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | splice_donor_variant | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | splice_donor_variant | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | splice_donor_variant | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | splice_donor_variant | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | splice_donor_variant | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| ERCC6 | R612* | Complete Match | Cisplatin (Chemotherapy) | Responsive | OV | Pre-clinical |
| PTEN | S59* | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | S59* | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | S59* | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | S59* | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | S59* | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | S59* | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | S59* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | S59* | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | S59* | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | S59* | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | S59* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | S59* | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | S59* | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | S59* | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | S59* | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | S59* | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | S59* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | S59* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | S59* | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | S59* | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | S59* | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | S59* | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | S59* | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | S59* | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | S59* | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| FGFR2 | V635A | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | V635A | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| KMT2A | R3744Q), MLL MUT* (R652* | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | R3744Q), MLL MUT* (R652* | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | R3744Q), MLL MUT* (R652* | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | R3744Q), MLL MUT* (R652* | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | R3744Q), MLL MUT* (R652* | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | R3744Q), MLL MUT* (R652* | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| SMARCA4 | E1426* | Complete Match | EZH2 inhibitor | Responsive | OVRT | Case report |
| SMARCA4 | E1426* | Complete Match | AURKA inhibitor | Responsive | NSCLC | Pre-clinical |
| SMARCA4 | E1426* | Complete Match | EZH2 inhibitor | Responsive | OV | Case report |
| SMARCA4 | E1426* | Different Alteration | EZH2 inhibitor | Responsive | OVRT | Case report |
| SMARCA4 | E1426* | Different Alteration | EZH2 inhibitor | Responsive | OV | Case report |
| NF1 | E1734* | Different Mutation | Vemurafenib (BRAF inhibitor) | Resistant | CM | Pre-clinical |
| NF1 | E1734* | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | HNC | Case report |
| NF1 | E1734* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | E1734* | Complete Match | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | E1734* | Complete Match | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Complete Match | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Complete Match | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | E1734* | Complete Match | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | E1734* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | NF | Late trials |
| NF1 | E1734* | Complete Match | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | E1734* | Complete Match | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Complete Match | Nilotinib (BCR-ABL inhibitor) | Responsive | MPN, PLEN | Pre-clinical |
| NF1 | E1734* | Complete Match | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | HNC, SG | Case report |
| NF1 | E1734* | Complete Match | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | E1734* | Complete Match | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | E1734* | Complete Match | MEK inhibitor | Responsive | LK, G | Pre-clinical |
| NF1 | E1734* | Complete Match | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | E1734* | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | E1734* | Complete Match | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Complete Match | MTOR inhibitor | Responsive | LK, G, MPN | Pre-clinical |
| NF1 | E1734* | Complete Match | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | E1734* | Complete Match | Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) | Responsive | HC | Case report |
| NF1 | E1734* | Complete Match | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | E1734* | Complete Match | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | E1734* | Complete Match | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | E1734* | Complete Match | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | E1734* | Complete Match | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | E1734* | Complete Match | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | E1734* | Complete Match | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | E1734* | Complete Match | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | E1734* | Complete Match | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Complete Match | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | E1734* | Complete Match | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | E1734* | Complete Match | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | E1734* | Different Alteration | MTOR inhibitor | Responsive | MPN, G, LK | Pre-clinical |
| NF1 | E1734* | Different Alteration | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | E1734* | Different Alteration | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | E1734* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | E1734* | Different Alteration | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Different Alteration | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | E1734* | Different Alteration | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | E1734* | Different Alteration | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | E1734* | Different Alteration | MEK inhibitor | Responsive | G, LK | Pre-clinical |
| NF1 | E1734* | Different Alteration | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | E1734* | Different Alteration | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Different Alteration | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | E1734* | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | E1734* | Different Alteration | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Different Alteration | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | E1734* | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | E1734* | Different Alteration | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | SG, HNC | Case report |
| NF1 | E1734* | Different Alteration | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | E1734* | Different Alteration | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | E1734* | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | E1734* | Different Alteration | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | E1734* | Different Alteration | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | E1734* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | E1734* | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | PLEN, MPN | Pre-clinical |
| NF1 | E1734* | Different Alteration | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | E1734* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | E1734* | Different Alteration | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Different Alteration | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | E1734* | Different Alteration | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | E1734* | Different Alteration | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | E1734* | Different Alteration | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| BRD4 | P723P | Different Alteration | BET inhibitor | Responsive | NMC | Case report |
| ESR1 | A593D | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| ROS1 | K1661Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | K1661Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | K1661Q | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | K1661Q | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | K1661Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| NRG1 | R155I | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Pre-clinical |
| NRG1 | R155I | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Case report |
| APC | E109*), APC MUT (S2223* | Complete Match | Tankyrase inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3R1 | R557*), PIK3R1 MUT (R348* | Complete Match | AKT inhibitor | Responsive | G | Pre-clinical |
| PIK3R1 | R557*), PIK3R1 MUT (R348* | Complete Match | PI3K pathway inhibitor | Responsive | ED | Case report |
| PDGFRA | I139I | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | MDPS, MDS, ECL, HES | FDA guidelines |
| ERBB4 | F401L | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| ATR | R1368* | Complete Match | Temozolomide (Chemotherapy) | Responsive | G | Pre-clinical |
| ATR | R1368* | Complete Match | Olaparib (PARP inhibitor) | Responsive | CANCER, OV | Pre-clinical |
| ATR | R1368* | Different Alteration | Olaparib (PARP inhibitor) | Responsive | OV, CANCER | Pre-clinical |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | Y1021C), PIK3CA MUT (R349* | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| RAF1 | S605F | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | PRAD | Pre-clinical |
| RAF1 | S605F | Different Alteration | Pan-RAF inhibitor | Responsive | PRAD | Pre-clinical |
| RAF1 | S605F | Different Alteration | U0126 (MEK inhibitor) | Responsive | PRAD | Pre-clinical |
| NTRK3 | T369N | Different Alteration | IGF1R inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | T369N | Different Alteration | PI3K pathway inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | T369N | Different Alteration | Midostaurin (Pan-TK inhibitor) | Responsive | BRCA | Pre-clinical |
| TP53 | L194R | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | L194R | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | L194R | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | L194R | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | L194R | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | L194R | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | L194R | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L194R | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L194R | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | L194R | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | L194R | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | L194R | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L194R | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | L194R | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L194R | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NF1 | splice_donor_variant | Different Mutation | Vemurafenib (BRAF inhibitor) | Resistant | CM | Pre-clinical |
| NF1 | splice_donor_variant | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | HNC | Case report |
| NF1 | splice_donor_variant | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_donor_variant | Complete Match | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | splice_donor_variant | Complete Match | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | splice_donor_variant | Complete Match | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Everolimus (MTOR inhibitor) | Responsive | NF | Late trials |
| NF1 | splice_donor_variant | Complete Match | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | splice_donor_variant | Complete Match | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Nilotinib (BCR-ABL inhibitor) | Responsive | MPN, PLEN | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Everolimus (MTOR inhibitor) | Responsive | HNC, SG | Case report |
| NF1 | splice_donor_variant | Complete Match | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | splice_donor_variant | Complete Match | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | MEK inhibitor | Responsive | LK, G | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_donor_variant | Complete Match | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | MTOR inhibitor | Responsive | LK, G, MPN | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) | Responsive | HC | Case report |
| NF1 | splice_donor_variant | Complete Match | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | splice_donor_variant | Complete Match | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | splice_donor_variant | Complete Match | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | splice_donor_variant | Complete Match | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | splice_donor_variant | Complete Match | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | splice_donor_variant | Complete Match | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | splice_donor_variant | Complete Match | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | splice_donor_variant | Complete Match | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_donor_variant | Complete Match | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | splice_donor_variant | Complete Match | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | splice_donor_variant | Different Alteration | MTOR inhibitor | Responsive | MPN, G, LK | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | splice_donor_variant | Different Alteration | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | splice_donor_variant | Different Alteration | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | splice_donor_variant | Different Alteration | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | splice_donor_variant | Different Alteration | MEK inhibitor | Responsive | G, LK | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | splice_donor_variant | Different Alteration | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | splice_donor_variant | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | splice_donor_variant | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_donor_variant | Different Alteration | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | SG, HNC | Case report |
| NF1 | splice_donor_variant | Different Alteration | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | splice_donor_variant | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_donor_variant | Different Alteration | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | splice_donor_variant | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_donor_variant | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | PLEN, MPN | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | splice_donor_variant | Different Alteration | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | splice_donor_variant | Different Alteration | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | splice_donor_variant | Different Alteration | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_donor_variant | Different Alteration | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| TP53 | P278S | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | P278S | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | P278S | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | P278S | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | P278S | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | P278S | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | P278S | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P278S | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P278S | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | P278S | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | P278S | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | P278S | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P278S | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | P278S | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P278S | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| KMT2D | W1491* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | LUSC | Pre-clinical |
| RB1 | Q383* | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | Q383* | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | Q383* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | Q383* | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | Q383* | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | Q383* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | Q383* | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| FGFR2 | L262P | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | L262P | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| PIK3CA | E545G), PIK3CA MUT (E545K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E545G), PIK3CA MUT (E545K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E545G), PIK3CA MUT (E545K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| ERBB4 | 3-UTRSNV | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| ALK | E780D | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | E780D | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | E780D | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | E780D | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | E780D | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | E780D | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | E780D | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | E780D | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | E780D | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | E780D | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | E780D | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | E780D | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | E780D | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | E780D | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | E780D | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | E780D | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | E780D | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | E780D | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | E780D | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| NOTCH2 | V1015A | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| EGFR | S246S | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | S246S | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| ROS1 | L567L), ROS1 MUT* (I745I), ROS1 MUT* (3-UTRSNV | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | L567L), ROS1 MUT* (I745I), ROS1 MUT* (3-UTRSNV | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | L567L), ROS1 MUT* (I745I), ROS1 MUT* (3-UTRSNV | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | L567L), ROS1 MUT* (I745I), ROS1 MUT* (3-UTRSNV | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | L567L), ROS1 MUT* (I745I), ROS1 MUT* (3-UTRSNV | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| MET | P485L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | G | Case report |
| PTEN | splice_acceptor_variant | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | splice_acceptor_variant | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | splice_acceptor_variant | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | splice_acceptor_variant | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | splice_acceptor_variant | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | splice_acceptor_variant | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | splice_acceptor_variant | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | splice_acceptor_variant | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | splice_acceptor_variant | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | splice_acceptor_variant | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | splice_acceptor_variant | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | splice_acceptor_variant | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | splice_acceptor_variant | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | splice_acceptor_variant | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | splice_acceptor_variant | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | splice_acceptor_variant | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | splice_acceptor_variant | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | splice_acceptor_variant | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | splice_acceptor_variant | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | splice_acceptor_variant | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | splice_acceptor_variant | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | splice_acceptor_variant | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | splice_acceptor_variant | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | splice_acceptor_variant | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | splice_acceptor_variant | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| KMT2A | P654P | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | P654P | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | P654P | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | P654P | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | P654P | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | P654P | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| ERBB4 | splice_acceptor_variant | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | CM | Pre-clinical |
| ERBB4 | splice_acceptor_variant | Different Mutation | ERBB2 inhibitor | Resistant | BRCA | Case report |
| ERBB4 | splice_acceptor_variant | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| TP53 | E294* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | E294* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | E294* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | E294* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | E294* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | E294* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E294* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E294* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E294* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | E294* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | E294* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | E294* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E294* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | E294* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E294* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| DNMT3A | R882H | Complete Match | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| AKT1 | L52R | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| AKT1 | L52R | Different Mutation | allosteric AKT inhibitor | Responsive | CANCER | Early trials |
| AKT1 | L52R | Different Mutation | non-allosteric AKT inhibitor | Responsive | CANCER | Early trials |
| AKT1 | L52R | Different Mutation | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| AKT1 | L52R | Different Mutation | Temsirolimus (MTOR inhibitor) | Responsive | ED | Early trials |
| AKT1 | L52R | Different Mutation | AKT inhibitor | Responsive | CANCER | Pre-clinical |
| AKT1 | L52R | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | FH | Case report |
| ESR1 | E380Q | Different Mutation | Fulvestrant (Hormonal therapy) | Resistant | BRCA | Pre-clinical |
| ESR1 | E380Q | Complete Match | novel ER degrader | Responsive | BRCA | Case report |
| ESR1 | E380Q | Complete Match | Tamoxifen (Hormonal therapy) | Resistant | BRCA | Early trials |
| ESR1 | E380Q | Complete Match | Exemestane (Hormonal therapy) | Resistant | BRCA | Late trials |
| ESR1 | E380Q | Complete Match | Fluvestrant (Hormonal therapy) | Responsive | BRCA | Late trials |
| ESR1 | E380Q | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| ALK | D525N | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | D525N | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | D525N | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | D525N | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | D525N | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | D525N | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | D525N | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | D525N | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | D525N | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | D525N | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | D525N | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | D525N | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | D525N | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | D525N | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | D525N | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | D525N | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | D525N | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | D525N | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | D525N | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| PIK3CA | R108H | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | R108H | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | R108H | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | R108H | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | R108H | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | R108H | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | R108H | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | R108H | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | R108H | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | R108H | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | R108H | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | R108H | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | R108H | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | R108H | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| RAF1 | Q253* | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | PRAD | Pre-clinical |
| RAF1 | Q253* | Different Alteration | Pan-RAF inhibitor | Responsive | PRAD | Pre-clinical |
| RAF1 | Q253* | Different Alteration | U0126 (MEK inhibitor) | Responsive | PRAD | Pre-clinical |
| BRAF | K698R | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | CM, LUAD, PRAD | Pre-clinical |
| BRAF | K698R | Different Alteration | MEK inhibitor | Responsive | LUAD, CM, PRAD | Pre-clinical |
| BRAF | K698R | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | OV | Case report |
| BRAF | K698R | Different Alteration | BRAF inhibitor;MEK inhibitor | Responsive | LUAD | Case report |
| STAG2 | R216* | Complete Match | PARP inhibitor | Responsive | G | Pre-clinical |
| PTEN | Y88* | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | Y88* | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | Y88* | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | Y88* | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | Y88* | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | Y88* | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | Y88* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | Y88* | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | Y88* | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | Y88* | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | Y88* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | Y88* | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | Y88* | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | Y88* | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | Y88* | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | Y88* | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | Y88* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | Y88* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | Y88* | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | Y88* | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | Y88* | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | Y88* | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | Y88* | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | Y88* | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | Y88* | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PIK3CA | E453K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E453K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E453K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E453K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E453K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E453K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E453K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E453K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E453K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E453K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E453K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E453K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E453K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E453K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | R282W | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R282W | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R282W | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R282W | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R282W | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R282W | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R282W | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R282W | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R282W | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R282W | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R282W | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R282W | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R282W | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R282W | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R282W | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NTRK3 | S359S | Different Alteration | IGF1R inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | S359S | Different Alteration | PI3K pathway inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | S359S | Different Alteration | Midostaurin (Pan-TK inhibitor) | Responsive | BRCA | Pre-clinical |
| FAT1 | Q3825* | Complete Match | BET inhibitor | Responsive | HNSC | Pre-clinical |
| RB1 | R552* | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | R552* | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | R552* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | R552* | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | R552* | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | R552* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | R552* | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| TP53 | V173M | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | V173M | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | V173M | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | V173M | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | V173M | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | V173M | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | V173M | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V173M | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V173M | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | V173M | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | V173M | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | V173M | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V173M | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | V173M | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V173M | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | L265R | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | L265R | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | L265R | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | L265R | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | L265R | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | L265R | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | L265R | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L265R | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L265R | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | L265R | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | L265R | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | L265R | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L265R | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | L265R | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L265R | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3R1 | splice_donor_variant | Complete Match | AKT inhibitor | Responsive | G | Pre-clinical |
| PIK3R1 | splice_donor_variant | Complete Match | PI3K pathway inhibitor | Responsive | ED | Case report |
| PTPRD | G574* | Complete Match | IGF1R inhibitor | Responsive | S | Case report |
| PDGFB | K155N | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | DFS | FDA guidelines |
| TP53 | R248W | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R248W | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R248W | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R248W | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R248W | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R248W | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R248W | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R248W | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R248W | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R248W | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R248W | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R248W | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R248W | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R248W | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R248W | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| FGFR2 | N550K), FGFR2 MUT (N550K | Different Alteration | FGFR inhibitor | Resistant | CH | Early trials |
| FGFR2 | N550K | Different Mutation | FGFR inhibitor | Responsive | LUSC | Pre-clinical |
| FGFR2 | N550K | Complete Match | Dovitinib (FGFR inhibitor) | Resistant | ED | Pre-clinical |
| FGFR2 | N550K | Complete Match | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | ED | Pre-clinical |
| FGFR2 | N550K | Complete Match | FGFR inhibitor | Responsive | ED | Pre-clinical |
| FGFR2 | N550K | Different Mutation | FGFR inhibitor | Responsive | L | Pre-clinical |
| FGFR2 | N550K | Different Mutation | FGFR inhibitor | Responsive | ED | Pre-clinical |
| FGFR2 | N550K | Different Mutation | FGFR inhibitor | Responsive | BT | Case report |
| FGFR2 | N550K | Different Alteration | FGFR inhibitor | Responsive | ST | Early trials |
| FGFR2 | N550K | Different Alteration | FGFR inhibitor | Responsive | BRCA | Case report |
| FGFR2 | N550K | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | N550K | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| BRCA1 | G1788V | Complete Match | Chemotherapy (PARP inhibitor;Chemotherapy) | Responsive | OV | Early trials |
| BRCA1 | G1788V | Complete Match | PARP inhibitor | Responsive | BRCA | Early trials |
| BRCA1 | G1788V | Complete Match | PARP inhibitor;Chemotherapy | Responsive | OV | Early trials |
| BRCA1 | G1788V | Complete Match | Rucaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | G1788V | Complete Match | Platinum Agent (Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | G1788V | Complete Match | WEE1 inhibitor | Responsive | CANCER | Case report |
| BRCA1 | G1788V | Complete Match | Platinum Agent (Chemotherapy) | Responsive | OV | Late trials |
| BRCA1 | G1788V | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| BRCA1 | G1788V | Complete Match | Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | G1788V | Complete Match | PARP inhibitor | Responsive | PA | Case report |
| BRCA1 | G1788V | Complete Match | Olaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | G1788V | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| NOTCH2 | R268S | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| TP53 | L252P | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | L252P | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | L252P | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | L252P | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | L252P | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | L252P | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | L252P | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L252P | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L252P | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | L252P | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | L252P | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | L252P | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L252P | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | L252P | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L252P | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ABL1 | P112Q | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| ABL1 | P112Q | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | P112Q | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| ABL1 | P112Q | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | P112Q | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| ABL1 | P112Q | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| TP53 | R213* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R213* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R213* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R213* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R213* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R213* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R213* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R213* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R213* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R213* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R213* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R213* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R213* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R213* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R213* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PTEN | K128N | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | K128N | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | K128N | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | K128N | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | K128N | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | K128N | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | K128N | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | K128N | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | K128N | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | K128N | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | K128N | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | K128N | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | K128N | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | K128N | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | K128N | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | K128N | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | K128N | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | K128N | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | K128N | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | K128N | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | K128N | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | K128N | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | K128N | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | K128N | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | K128N | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| EZH2 | S639* | Different Mutation | EZH2 inhibitor | Responsive | LY | Pre-clinical |
| EZH2 | S639* | Different Mutation | EZH2 inhibitor | Responsive | LY | Early trials |
| PML | P419P | Different Alteration | Volasertib (PLK1 inhibitor) | Responsive | AML | Early trials |
| PML | P419P | Different Alteration | Tretinoin (Retinoid) | Responsive | APML | FDA guidelines |
| PML | P419P | Different Alteration | Tretinoin;Arsenic Trioxide (Retinoid;Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | C2068Y | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | C2068Y | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | C2068Y | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | C2068Y | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | C2068Y | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | C2068Y | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| TP53 | G245D | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | G245D | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | G245D | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | G245D | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | G245D | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | G245D | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | G245D | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G245D | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G245D | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | G245D | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | G245D | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | G245D | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G245D | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | G245D | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G245D | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | H193L | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | H193L | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | H193L | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | H193L | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | H193L | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | H193L | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | H193L | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H193L | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H193L | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | H193L | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | H193L | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | H193L | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H193L | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | H193L | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H193L | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| BCR | Q300H | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| BCR | Q300H | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| BCR | Q300H | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | Q300H | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | Q300H | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| BCR | Q300H | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ALK | M301I | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | M301I | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | M301I | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | M301I | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | M301I | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | M301I | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | M301I | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | M301I | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | M301I | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | M301I | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | M301I | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | M301I | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | M301I | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | M301I | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | M301I | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | M301I | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | M301I | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | M301I | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | M301I | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| ERBB4 | N278S | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| TP53 | V216M | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | V216M | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | V216M | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | V216M | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | V216M | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | V216M | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | V216M | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V216M | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V216M | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | V216M | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | V216M | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | V216M | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V216M | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | V216M | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V216M | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| EGFR | C526S | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | C526S | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| TP53 | R273P | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R273P | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R273P | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R273P | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R273P | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R273P | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R273P | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R273P | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R273P | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R273P | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R273P | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R273P | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R273P | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R273P | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R273P | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ROS1 | T2266R | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | T2266R | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | T2266R | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | T2266R | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | T2266R | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| EGFR | Y900Y | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | Y900Y | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| TP53 | E198* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | E198* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | E198* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | E198* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | E198* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | E198* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E198* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E198* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E198* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | E198* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | E198* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | E198* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E198* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | E198* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E198* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (M1004I | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| PDGFRA | E571K | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | MDPS, MDS, ECL, HES | FDA guidelines |
| ATM | splice_donor_variant | Different Mutation | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ATM | splice_donor_variant | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| ATM | splice_donor_variant | Complete Match | Olaparib (PARP inhibitor) | Responsive | ST, PRAD | Early trials |
| ATM | splice_donor_variant | Complete Match | PARP inhibitor | Responsive | ST | Early trials |
| ATM | splice_donor_variant | Complete Match | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | splice_donor_variant | Complete Match | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | splice_donor_variant | Complete Match | Temozolomide (Chemotherapy) | Responsive | G | Pre-clinical |
| ATM | splice_donor_variant | Complete Match | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | splice_donor_variant | Different Alteration | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | splice_donor_variant | Different Alteration | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | splice_donor_variant | Different Alteration | PARP inhibitor | Responsive | ST | Early trials |
| ATM | splice_donor_variant | Different Alteration | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | splice_donor_variant | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| TP53 | V197G | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | V197G | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | V197G | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | V197G | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | V197G | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | V197G | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | V197G | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V197G | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V197G | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | V197G | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | V197G | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | V197G | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V197G | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | V197G | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V197G | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| SETD2 | S180* | Complete Match | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| SETD2 | S180* | Different Alteration | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Y205C | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Y205C | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Y205C | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Y205C | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Y205C | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Y205C | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Y205C | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y205C | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y205C | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Y205C | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Y205C | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Y205C | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y205C | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Y205C | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y205C | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| KMT2A | Q900* | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | Q900* | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | Q900* | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | Q900* | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | Q900* | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | Q900* | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| ATM | R2993* | Different Mutation | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ATM | R2993* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| ATM | R2993* | Complete Match | Olaparib (PARP inhibitor) | Responsive | ST, PRAD | Early trials |
| ATM | R2993* | Complete Match | PARP inhibitor | Responsive | ST | Early trials |
| ATM | R2993* | Complete Match | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | R2993* | Complete Match | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | R2993* | Complete Match | Temozolomide (Chemotherapy) | Responsive | G | Pre-clinical |
| ATM | R2993* | Complete Match | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | R2993* | Different Alteration | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | R2993* | Different Alteration | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | R2993* | Different Alteration | PARP inhibitor | Responsive | ST | Early trials |
| ATM | R2993* | Different Alteration | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | R2993* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| PDGFRA | R822H | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | R | Pre-clinical |
| PDGFRA | R822H | Complete Match | Sunitinib (Pan-TK inhibitor) | Responsive | GIST | NCCN guidelines |
| PDGFRA | R822H | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | GIST | NCCN guidelines |
| PDGFRA | R822H | Complete Match | Regorafenib (Pan-kinase inhibitor) | Responsive | GIST | NCCN guidelines |
| PDGFRA | R822H | Different Mutation | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | CM | Pre-clinical |
| PDGFRA | R822H | Different Mutation | Crenolanib (FLT3 inhibitor) | Responsive | CM | Pre-clinical |
| PDGFRA | R822H | Different Mutation | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Resistant | HES | Case report |
| PDGFRA | R822H | Different Mutation | Crenolanib (FLT3 inhibitor) | Responsive | GIST | Early trials |
| PDGFRA | R822H | Different Mutation | HSP90 inhibitor | Responsive | GIST | Pre-clinical |
| PDGFRA | R822H | Different Mutation | HSP90 inhibitor (HSP90 inhibitor) | Responsive | GIST | Pre-clinical |
| PDGFRA | R822H | Different Mutation | Dasatinib (BCR-ABL inhibitor) | Responsive | GIST | Pre-clinical |
| PDGFRA | R822H | Different Mutation | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Resistant | GIST | Late trials |
| PDGFRA | R822H | Different Mutation | PDGFR inhibitor | Responsive | GIST | Early trials |
| PDGFRA | R822H | Different Mutation | Sunitinib (Pan-TK inhibitor) | Resistant | GIST | Late trials |
| PDGFRA | R822H | Different Mutation | Sorafenib (Pan-TK inhibitor) | Responsive | GIST | Early trials |
| PDGFRA | R822H | Different Mutation | Sunitinib (Pan-TK inhibitor) | Responsive | GIST | Late trials |
| PDGFRA | R822H | Different Alteration | PDGFR inhibitor | No Responsive | G | Pre-clinical |
| PDGFRA | R822H | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | MDPS, MDS, ECL, HES | FDA guidelines |
| RB1 | S215* | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | S215* | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | S215* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | S215* | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | S215* | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | S215* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | S215* | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| AKT3 | 3-UTRSNV | Different Alteration | ATP competitive AKT inhibitor | Responsive | BRCA | Pre-clinical |
| MET | Y390Y | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | G | Case report |
| EGFR | S198S | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | S198S | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| ATM | Q2269* | Different Mutation | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ATM | Q2269* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| ATM | Q2269* | Complete Match | Olaparib (PARP inhibitor) | Responsive | ST, PRAD | Early trials |
| ATM | Q2269* | Complete Match | PARP inhibitor | Responsive | ST | Early trials |
| ATM | Q2269* | Complete Match | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | Q2269* | Complete Match | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | Q2269* | Complete Match | Temozolomide (Chemotherapy) | Responsive | G | Pre-clinical |
| ATM | Q2269* | Complete Match | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | Q2269* | Different Alteration | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | Q2269* | Different Alteration | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | Q2269* | Different Alteration | PARP inhibitor | Responsive | ST | Early trials |
| ATM | Q2269* | Different Alteration | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | Q2269* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| TP53 | E51* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | E51* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | E51* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | E51* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | E51* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | E51* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E51* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E51* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E51* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | E51* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | E51* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | E51* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E51* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | E51* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E51* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ARID1A | S711* | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | S711* | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | S711* | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | S711* | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| CDH1 | Q255* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| CDKN1A | S98* | Complete Match | CDK2/4 inhibitor | Responsive | CANCER | Pre-clinical |
| CDKN1A | S98* | Different Alteration | CDK2/4 inhibitor | Responsive | CANCER | Pre-clinical |
| BRD4 | P15L | Different Alteration | BET inhibitor | Responsive | NMC | Case report |
| PTEN | H123D | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | H123D | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | H123D | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | H123D | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | H123D | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | H123D | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | H123D | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | H123D | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | H123D | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | H123D | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | H123D | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | H123D | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | H123D | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | H123D | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | H123D | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | H123D | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | H123D | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | H123D | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | H123D | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | H123D | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | H123D | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | H123D | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | H123D | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | H123D | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | H123D | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| NOTCH2 | L566F | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| KRAS | G12C | Complete Match | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | FDA guidelines |
| KRAS | G12C | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | FDA guidelines |
| KRAS | G12C | Different Mutation | Cetuximab (EGFR mAb inhibitor) | No Responsive | COREAD | Late trials |
| KRAS | G12C | Complete Match | MEK inhibitor | Responsive | ALL | Pre-clinical |
| KRAS | G12C | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Resistant | GIST | Case report |
| KRAS | G12C | Complete Match | MEK inhibitor | Responsive | OV, CER, AML | Pre-clinical |
| KRAS | G12C | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Responsive | L | Early trials |
| KRAS | G12C | Complete Match | MEK inhibitor;PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12C | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | NCCN guidelines |
| KRAS | G12C | Complete Match | Sorafenib;MEK inhibitor (Pan-TK inhibitor;MEK inhibitor) | Responsive | HC | Early trials |
| KRAS | G12C | Complete Match | EGFR inhibitor | Resistant | L | NCCN guidelines |
| KRAS | G12C | Complete Match | CDK4 inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12C | Complete Match | Selumetinib (MEK inhibitor) | Responsive | NSCLC | Early trials |
| KRAS | G12C | Complete Match | BET inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12C | Complete Match | Decitabine;BCL2 inhibitor (Chemotherapy;BCL2 inhibitor) | Responsive | OV | Pre-clinical |
| KRAS | G12C | Complete Match | FAK inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12C | Complete Match | EGFR inhibitor | Resistant | NSCLC | Pre-clinical |
| KRAS | G12C | Complete Match | EZH2 inhibitor | Resistant | CANCER | Pre-clinical |
| KRAS | G12C | Complete Match | MEK inhibitor | Responsive | BT, L | Early trials |
| KRAS | G12C | Complete Match | MEK inhibitor;IGF1R inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12C | Complete Match | MTOR inhibitor;BH3 mimetics | Responsive | COREAD | Pre-clinical |
| KRAS | G12C | Complete Match | EGFR mAb inhibitor;MEK inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12C | Complete Match | pan-RAF inhibitor | Responsive | ED | Case report |
| KRAS | G12C | Complete Match | EGFR mAb inhibitor | Resistant | ST | Pre-clinical |
| KRAS | G12C | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | L | Early trials |
| KRAS | G12C | Complete Match | Selumetinib (MEK inhibitor) | No Responsive | L | Early trials |
| KRAS | G12C | Complete Match | CDK4/6 inhibitor;MEK inhibitor | Responsive | L | Early trials |
| KRAS | G12C | Complete Match | Trametinib;Ponatinib (MEK inhibitor;BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | LUAD | Pre-clinical |
| KRAS | G12C | Complete Match | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Resistant | COREAD | Late trials |
| KRAS | G12C | Complete Match | pan-RAF inhibitor | Responsive | L | Early trials |
| KRAS | G12C | Complete Match | JAK/TBK1/IKKε inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12C | Complete Match | FAS inhibitor | Responsive | L | Case report |
| KRAS | G12C | Complete Match | HSP90 inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12C | Complete Match | ERK inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12C | Complete Match | PI3K pathway inhibitor;MEK inhibitor | No Responsive | PA | Early trials |
| KRAS | G12C | Complete Match | MEK inhibitor;BCL-XL inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12C | Complete Match | Gemcitabine;MEK inhibitor (Chemotherapy;MEK inhibitor) | Responsive | PA | Early trials |
| KRAS | G12C | Complete Match | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | NCCN guidelines |
| KRAS | G12C | Complete Match | PI3K pathway inhibitor | Resistant | ED | Pre-clinical |
| KRAS | G12C | Complete Match | CDK4/6 inhibitor;MEK inhibitor | Responsive | CESC | Pre-clinical |
| KRAS | G12C | Different Alteration | BRAF inhibitor;MEK inhibitor | Resistant | COREAD | Case report |
| KRAS | G12C | Different Alteration | BRAF inhibitor;EGFR mAb inhibitor | Resistant | COREAD | Case report |
| FBXW7 | Y545C | Complete Match | Steroid | Responsive | ALL | Late trials |
| FBXW7 | Y545C | Complete Match | Tubulin inhibitor | Resistant | CANCER | Pre-clinical |
| FBXW7 | Y545C | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | COREAD | Pre-clinical |
| FBXW7 | Y545C | Different Alteration | Tubulin inhibitor | Resistant | CANCER | Pre-clinical |
| TP53 | F270I | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | F270I | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | F270I | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | F270I | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | F270I | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | F270I | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | F270I | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | F270I | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | F270I | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | F270I | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | F270I | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | F270I | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | F270I | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | F270I | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | F270I | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R273H | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R273H | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R273H | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R273H | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R273H | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R273H | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R273H | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R273H | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R273H | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R273H | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R273H | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R273H | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R273H | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R273H | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R273H | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E285K | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | E285K | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | E285K | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | E285K | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | E285K | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | E285K | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E285K | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E285K | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E285K | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | E285K | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | E285K | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | E285K | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E285K | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | E285K | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E285K | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NTRK1 | P695P | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Case report |
| NTRK1 | P695P | Different Alteration | Pan-TKR inhibitor | Responsive | CANCER | Early trials |
| NTRK1 | P695P | Different Alteration | Pan-TK inhibitor | Responsive | LUAD | Pre-clinical |
| NTRK1 | P695P | Different Alteration | Pan-TK inhibitor | Responsive | COREAD | Case report |
| TP53 | D281V | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | D281V | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | D281V | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | D281V | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | D281V | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | D281V | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | D281V | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | D281V | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | D281V | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | D281V | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | D281V | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | D281V | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | D281V | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | D281V | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | D281V | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ERBB3 | V104L | Different Mutation | PI3K pathway inhibitor;MEK inhibitor | Responsive | CANCER | Pre-clinical |
| ERBB3 | V104L | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB3 | V104L | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB3 | V104L | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB3 | V104L | Different Mutation | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB3 | V104L | Different Mutation | ERBB3 mAb inhibitor | Responsive | CANCER | Pre-clinical |
| ERBB3 | V104L | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| KRAS | G12V | Complete Match | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | FDA guidelines |
| KRAS | G12V | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | FDA guidelines |
| KRAS | G12V | Different Mutation | Cetuximab (EGFR mAb inhibitor) | No Responsive | COREAD | Late trials |
| KRAS | G12V | Complete Match | MEK inhibitor | Responsive | ALL | Pre-clinical |
| KRAS | G12V | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Resistant | GIST | Case report |
| KRAS | G12V | Complete Match | MEK inhibitor | Responsive | OV, CER, AML | Pre-clinical |
| KRAS | G12V | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Responsive | L | Early trials |
| KRAS | G12V | Complete Match | MEK inhibitor;PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12V | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | NCCN guidelines |
| KRAS | G12V | Complete Match | Sorafenib;MEK inhibitor (Pan-TK inhibitor;MEK inhibitor) | Responsive | HC | Early trials |
| KRAS | G12V | Complete Match | EGFR inhibitor | Resistant | L | NCCN guidelines |
| KRAS | G12V | Complete Match | CDK4 inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12V | Complete Match | Selumetinib (MEK inhibitor) | Responsive | NSCLC | Early trials |
| KRAS | G12V | Complete Match | BET inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12V | Complete Match | Decitabine;BCL2 inhibitor (Chemotherapy;BCL2 inhibitor) | Responsive | OV | Pre-clinical |
| KRAS | G12V | Complete Match | FAK inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12V | Complete Match | EGFR inhibitor | Resistant | NSCLC | Pre-clinical |
| KRAS | G12V | Complete Match | EZH2 inhibitor | Resistant | CANCER | Pre-clinical |
| KRAS | G12V | Complete Match | MEK inhibitor | Responsive | BT, L | Early trials |
| KRAS | G12V | Complete Match | MEK inhibitor;IGF1R inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12V | Complete Match | MTOR inhibitor;BH3 mimetics | Responsive | COREAD | Pre-clinical |
| KRAS | G12V | Complete Match | EGFR mAb inhibitor;MEK inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12V | Complete Match | pan-RAF inhibitor | Responsive | ED | Case report |
| KRAS | G12V | Complete Match | EGFR mAb inhibitor | Resistant | ST | Pre-clinical |
| KRAS | G12V | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | L | Early trials |
| KRAS | G12V | Complete Match | Selumetinib (MEK inhibitor) | No Responsive | L | Early trials |
| KRAS | G12V | Complete Match | CDK4/6 inhibitor;MEK inhibitor | Responsive | L | Early trials |
| KRAS | G12V | Complete Match | Trametinib;Ponatinib (MEK inhibitor;BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | LUAD | Pre-clinical |
| KRAS | G12V | Complete Match | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Resistant | COREAD | Late trials |
| KRAS | G12V | Complete Match | pan-RAF inhibitor | Responsive | L | Early trials |
| KRAS | G12V | Complete Match | JAK/TBK1/IKKε inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12V | Complete Match | FAS inhibitor | Responsive | L | Case report |
| KRAS | G12V | Complete Match | HSP90 inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12V | Complete Match | ERK inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12V | Complete Match | PI3K pathway inhibitor;MEK inhibitor | No Responsive | PA | Early trials |
| KRAS | G12V | Complete Match | MEK inhibitor;BCL-XL inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12V | Complete Match | Gemcitabine;MEK inhibitor (Chemotherapy;MEK inhibitor) | Responsive | PA | Early trials |
| KRAS | G12V | Complete Match | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | NCCN guidelines |
| KRAS | G12V | Complete Match | PI3K pathway inhibitor | Resistant | ED | Pre-clinical |
| KRAS | G12V | Complete Match | CDK4/6 inhibitor;MEK inhibitor | Responsive | CESC | Pre-clinical |
| KRAS | G12V | Different Alteration | BRAF inhibitor;MEK inhibitor | Resistant | COREAD | Case report |
| KRAS | G12V | Different Alteration | BRAF inhibitor;EGFR mAb inhibitor | Resistant | COREAD | Case report |
| NOTCH1 | A2441T | Different Alteration | Gamma secretase inhibitor | Responsive | ALL | Pre-clinical |
| NOTCH1 | A2441T | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| TP53 | C124* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C124* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C124* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C124* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C124* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C124* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C124* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C124* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C124* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C124* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C124* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C124* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C124* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C124* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C124* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | D350G | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | D350G | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | D350G | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | D350G | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | D350G | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | D350G | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | D350G | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | D350G | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | D350G | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | D350G | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | D350G | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | D350G | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | D350G | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | D350G | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| MET | V797M | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | G | Case report |
| ERBB3 | D297Y | Different Mutation | PI3K pathway inhibitor;MEK inhibitor | Responsive | CANCER | Pre-clinical |
| ERBB3 | D297Y | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB3 | D297Y | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB3 | D297Y | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB3 | D297Y | Different Mutation | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB3 | D297Y | Different Mutation | ERBB3 mAb inhibitor | Responsive | CANCER | Pre-clinical |
| ERBB3 | D297Y | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| MET | G1364G | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | G | Case report |
| MET | Q830L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | G | Case report |
| EGFR | A1201V | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | A1201V | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| ABL1 | splice_acceptor_variant | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| ABL1 | splice_acceptor_variant | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | splice_acceptor_variant | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| ABL1 | splice_acceptor_variant | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | splice_acceptor_variant | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| ABL1 | splice_acceptor_variant | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| ATM | splice_acceptor_variant | Different Mutation | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ATM | splice_acceptor_variant | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| ATM | splice_acceptor_variant | Complete Match | Olaparib (PARP inhibitor) | Responsive | ST, PRAD | Early trials |
| ATM | splice_acceptor_variant | Complete Match | PARP inhibitor | Responsive | ST | Early trials |
| ATM | splice_acceptor_variant | Complete Match | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | splice_acceptor_variant | Complete Match | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | splice_acceptor_variant | Complete Match | Temozolomide (Chemotherapy) | Responsive | G | Pre-clinical |
| ATM | splice_acceptor_variant | Complete Match | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | splice_acceptor_variant | Different Alteration | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ATM | splice_acceptor_variant | Different Alteration | DNA-PKc inhibitor | Responsive | LY | Pre-clinical |
| ATM | splice_acceptor_variant | Different Alteration | PARP inhibitor | Responsive | ST | Early trials |
| ATM | splice_acceptor_variant | Different Alteration | ATR inhibitor | Responsive | COREAD | Case report |
| ATM | splice_acceptor_variant | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (P539R | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | C135Y | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C135Y | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C135Y | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C135Y | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C135Y | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C135Y | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C135Y | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C135Y | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C135Y | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C135Y | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C135Y | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C135Y | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C135Y | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C135Y | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C135Y | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R248Q | Complete Match | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R248Q | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R248Q | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R248Q | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R248Q | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R248Q | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R248Q | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R248Q | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R248Q | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R248Q | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R248Q | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R248Q | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R248Q | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R248Q | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R248Q | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Y220S | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Y220S | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Y220S | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Y220S | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Y220S | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Y220S | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Y220S | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y220S | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y220S | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Y220S | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Y220S | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Y220S | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y220S | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Y220S | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y220S | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NTRK3 | V753G | Different Alteration | IGF1R inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | V753G | Different Alteration | PI3K pathway inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | V753G | Different Alteration | Midostaurin (Pan-TK inhibitor) | Responsive | BRCA | Pre-clinical |
| FGFR2 | V342V | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | V342V | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| NOTCH1 | P2399S | Different Alteration | Gamma secretase inhibitor | Responsive | ALL | Pre-clinical |
| NOTCH1 | P2399S | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | C124S | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | C124S | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | C124S | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | C124S | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | C124S | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | C124S | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | C124S | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | C124S | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | C124S | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | C124S | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | C124S | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | C124S | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | C124S | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | C124S | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | C124S | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | C124S | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | C124S | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | C124S | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | C124S | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | C124S | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | C124S | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | C124S | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | C124S | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | C124S | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | C124S | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| NOTCH1 | S2523L | Different Alteration | Gamma secretase inhibitor | Responsive | ALL | Pre-clinical |
| NOTCH1 | S2523L | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| EGFR | E114K | Different Alteration | Cetuximab (EGFR mAb inhibitor) | Responsive | COREAD | FDA guidelines |
| EGFR | E114K | Different Alteration | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | FDA guidelines |
| EGFR | E114K | Different Mutation | Rindopepimut (Vaccine) | Responsive | GB | Late trials |
| EGFR | E114K | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | E114K | Different Mutation | Gefitinib (EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | E114K | Different Mutation | HSP90 inhibitor | Responsive | L | Early trials |
| EGFR | E114K | Different Mutation | Afatinib;Cetuximab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) | Responsive | L | Early trials |
| EGFR | E114K | Different Mutation | MEK inhibitor | Responsive | L | Pre-clinical |
| EGFR | E114K | Different Mutation | EGFR TK inhibitor | Responsive | L | Late trials |
| EGFR | E114K | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | NCCN guidelines |
| EGFR | E114K | Different Mutation | Osimertinib (EGFR inhibitor) | Resistant | L | Early trials |
| EGFR | E114K | Different Mutation | EGFR-TKI's (EGFR inhibitor) | Resistant | L | Late trials |
| EGFR | E114K | Different Mutation | HSP90 inhibitor | Responsive | L | Case report |
| EGFR | E114K | Different Mutation | EGFR inhibitor | Resistant | L | Late trials |
| EGFR | E114K | Different Mutation | Poziotinib (EGFR inhibitor) | Responsive | L | Early trials |
| EGFR | E114K | Different Mutation | Osimertinib (EGFR inhibitor) | Responsive | L | Pre-clinical |
| EGFR | E114K | Different Mutation | HSP90 inhibitor (HSP90 inhibitor) | Responsive | L | Early trials |
| EGFR | E114K | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | G | Pre-clinical |
| EGFR | E114K | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | E114K | Different Mutation | Osimertinib (EGFR inhibitor) | Responsive | L | Early trials |
| EGFR | E114K | Different Mutation | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| EGFR | E114K | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Responsive | COREAD | Case report |
| EGFR | E114K | Different Mutation | novel EGFR mAb inhibitor | Responsive | COREAD | Early trials |
| EGFR | E114K | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| EGFR | E114K | Different Mutation | Cetuximab;Sirolimus (EGFR mAb inhibitor;MTOR inhibitor) | Responsive | HNC | Case report |
| EGFR | E114K | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | E114K | Different Mutation | Gefitinib (EGFR inhibitor) | No Responsive | HNC | Case report |
| EGFR | E114K | Different Mutation | EGFR inhibitor | Responsive | L | Early trials |
| EGFR | E114K | Different Mutation | Erlotinib (EGFR inhibitor) | Resistant | L | NCCN/CAP guidelines |
| EGFR | E114K | Different Mutation | Osimertinib (EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | E114K | Different Mutation | EGFR inhibitor | Responsive | NSCLC | Late trials |
| EGFR | E114K | Different Mutation | Afatinib;Nimotuzumab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) | Responsive | L | Early trials |
| EGFR | E114K | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Resistant | L | NCCN/CAP guidelines |
| EGFR | E114K | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | L | Early trials |
| EGFR | E114K | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | L | Late trials |
| EGFR | E114K | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Pre-clinical |
| EGFR | E114K | Different Mutation | Erlotinib (EGFR inhibitor) | No Responsive | L | Case report |
| EGFR | E114K | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | ED | Case report |
| EGFR | E114K | Different Mutation | EGFR inhibitor | No Responsive | G | Early trials |
| EGFR | E114K | Different Mutation | EGFR inhibitor | Resistant | NSCLC | Case report |
| EGFR | E114K | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| EGFR | E114K | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant;Resistant | COREAD | Pre-clinical;Case report |
| EGFR | E114K | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Responsive | HNC | Case report |
| EGFR | E114K | Different Alteration | Gefitinib (EGFR inhibitor) | Responsive | ED | Late trials |
| EGFR | E114K | Different Alteration | Gefitinib (EGFR inhibitor) | No Responsive | HNC | Early trials |
| EGFR | E114K | Different Alteration | EGFR inhibitor | Responsive | HNSC | Case report |
| EGFR | E114K | Different Alteration | EGFR inhibitor | No Responsive | G | Early trials |
| EGFR | E114K | Different Alteration | Erlotinib (EGFR inhibitor) | No Responsive | L | Early trials |
| EGFR | E114K | Different Alteration | EGFR mAb inhibitor | Responsive | COREAD | Late trials |
| EGFR | E114K | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | E114K | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| AKT3 | S375* | Different Alteration | ATP competitive AKT inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK1 | Q626K | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Case report |
| NTRK1 | Q626K | Different Alteration | Pan-TKR inhibitor | Responsive | CANCER | Early trials |
| NTRK1 | Q626K | Different Alteration | Pan-TK inhibitor | Responsive | LUAD | Pre-clinical |
| NTRK1 | Q626K | Different Alteration | Pan-TK inhibitor | Responsive | COREAD | Case report |
| ARID1A | Q2037* | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q2037* | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q2037* | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | Q2037* | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| ERBB4 | T703K | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| TP53 | P278T | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | P278T | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | P278T | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | P278T | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | P278T | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | P278T | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | P278T | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P278T | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P278T | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | P278T | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | P278T | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | P278T | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P278T | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | P278T | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P278T | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| HRAS | G13R | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | CER | Pre-clinical |
| HRAS | G13R | Complete Match | MEK inhibitor +/- MTOR inhibitor | Responsive | AML | Pre-clinical |
| HRAS | G13R | Complete Match | MTOR inhibitor | Responsive | CESC | Pre-clinical |
| HRAS | G13R | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | Responsive | CANCER | Early trials |
| ABL1 | D482E | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| ABL1 | D482E | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | D482E | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| ABL1 | D482E | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | D482E | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| ABL1 | D482E | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| TP53 | L265P | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | L265P | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | L265P | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | L265P | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | L265P | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | L265P | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | L265P | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L265P | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L265P | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | L265P | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | L265P | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | L265P | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L265P | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | L265P | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L265P | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| CDKN1B | S27* | Complete Match | CDK2/4 inhibitor | Responsive | CANCER | Pre-clinical |
| CDKN1B | S27* | Different Alteration | CDK2/4 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | P151H | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | P151H | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | P151H | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | P151H | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | P151H | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | P151H | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | P151H | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P151H | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P151H | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | P151H | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | P151H | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | P151H | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P151H | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | P151H | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P151H | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R248W), TP53 MUT (L114* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R248W), TP53 MUT (L114* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R248W), TP53 MUT (L114* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R248W), TP53 MUT (L114* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R248W), TP53 MUT (L114* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R248W), TP53 MUT (L114* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R248W), TP53 MUT (L114* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R248W), TP53 MUT (L114* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R248W), TP53 MUT (L114* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R248W), TP53 MUT (L114* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R248W), TP53 MUT (L114* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R248W), TP53 MUT (L114* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R248W), TP53 MUT (L114* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R248W), TP53 MUT (L114* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R248W), TP53 MUT (L114* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | G245S | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | G245S | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | G245S | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | G245S | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | G245S | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | G245S | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | G245S | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G245S | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G245S | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | G245S | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | G245S | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | G245S | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G245S | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | G245S | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G245S | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| EPHA2 | CdsStopSNV | Different Mutation | MTOR inhibitor | Responsive | LUSC | Pre-clinical |
| EPHA2 | CdsStopSNV | Different Mutation | Dasatinib (BCR-ABL inhibitor) | Responsive | LUSC | Pre-clinical |
| EPHA2 | CdsStopSNV | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | CANCER | Pre-clinical |
| TP53 | F270S | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | F270S | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | F270S | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | F270S | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | F270S | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | F270S | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | F270S | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | F270S | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | F270S | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | F270S | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | F270S | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | F270S | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | F270S | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | F270S | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | F270S | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| JAK2 | R115I | Different Alteration | Ruxolitinib (JAK inhibitor) | Responsive | ALL | Pre-clinical |
| NOTCH2 | R1604S | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| BCOR | S3* | Complete Match | Enzastaurin (PKCb inhibitor) | Responsive | ST | Pre-clinical |
| PDGFRA | T361S | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | MDPS, MDS, ECL, HES | FDA guidelines |
| RET | T636T | Different Alteration | Nintedanib (Pan-TK inhibitor) | Responsive | LUAD | Case report |
| RET | T636T | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Early trials |
| RET | T636T | Different Alteration | RET inhibitor | Responsive | LUAD | Pre-clinical |
| RET | T636T | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | T636T | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | T636T | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | THCA | Pre-clinical |
| RET | T636T | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | T636T | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | T636T | Different Alteration | RET inhibitor | Responsive | TH | Pre-clinical |
| PIK3CA | Q546P | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | Q546P | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | Q546P | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | Q546P | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | Q546P | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | Q546P | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | Q546P | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | Q546P | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | Q546P | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | Q546P | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | Q546P | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | Q546P | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | Q546P | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | Q546P | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| ESR1 | 5-UTRBlockSubstitution | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| PIK3CA | E453K), PIK3CA MUT (E81K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E453K), PIK3CA MUT (E81K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E453K), PIK3CA MUT (E81K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| CDKN1B | E105* | Complete Match | CDK2/4 inhibitor | Responsive | CANCER | Pre-clinical |
| CDKN1B | E105* | Different Alteration | CDK2/4 inhibitor | Responsive | CANCER | Pre-clinical |
| NRG1 | E579E | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Pre-clinical |
| NRG1 | E579E | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Case report |
| NOTCH2 | V1666F | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | K266* | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | K266* | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | K266* | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | K266* | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | K266* | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | K266* | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | K266* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | K266* | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | K266* | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | K266* | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | K266* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | K266* | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | K266* | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | K266* | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | K266* | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | K266* | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | K266* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | K266* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | K266* | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | K266* | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | K266* | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | K266* | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | K266* | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | K266* | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | K266* | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| NOTCH2 | G476* | Different Mutation | Mk-0752 (Gamma secretase inhibitor) | Responsive | ALL, AML, BRCA | Early trials |
| NOTCH2 | G476* | Different Mutation | OMP-59R5 (NOTCH2 inhibitor) | Responsive | SOLID | Early trials |
| NOTCH2 | G476*), NOTCH2 MUT* (S955N | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| BRD4 | T296P | Different Alteration | BET inhibitor | Responsive | NMC | Case report |
| CDH1 | Q195* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| CDH1 | E494* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| NTRK1 | R342Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Case report |
| NTRK1 | R342Q | Different Alteration | Pan-TKR inhibitor | Responsive | CANCER | Early trials |
| NTRK1 | R342Q | Different Alteration | Pan-TK inhibitor | Responsive | LUAD | Pre-clinical |
| NTRK1 | R342Q | Different Alteration | Pan-TK inhibitor | Responsive | COREAD | Case report |
| PIK3CA | C420R | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | C420R | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | C420R | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | C420R | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | C420R | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | C420R | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | C420R | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | C420R | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | C420R | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | C420R | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | C420R | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | C420R | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | C420R | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | C420R | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| ESR1 | P222S | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| NOTCH2 | Q921Q | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| TP53 | E258Q | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | E258Q | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | E258Q | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | E258Q | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | E258Q | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | E258Q | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E258Q | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E258Q | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E258Q | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | E258Q | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | E258Q | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | E258Q | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E258Q | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | E258Q | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E258Q | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NTRK3 | R683S | Different Alteration | IGF1R inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | R683S | Different Alteration | PI3K pathway inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | R683S | Different Alteration | Midostaurin (Pan-TK inhibitor) | Responsive | BRCA | Pre-clinical |
| PIK3CA | E726G | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E726G | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E726G | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E726G | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E726G | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E726G | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E726G | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E726G | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E726G | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E726G | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E726G | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E726G | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E726G | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E726G | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| PIK3CA | E545K), PIK3CA MUT (E726K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E545K), PIK3CA MUT (E726K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E545K), PIK3CA MUT (E726K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | V274F | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | V274F | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | V274F | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | V274F | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | V274F | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | V274F | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | V274F | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V274F | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V274F | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | V274F | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | V274F | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | V274F | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V274F | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | V274F | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V274F | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ARID1A | R1989* | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | R1989* | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | R1989* | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | R1989* | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| PTEN | R130P | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | R130P | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | R130P | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | R130P | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | R130P | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | R130P | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | R130P | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | R130P | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | R130P | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | R130P | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | R130P | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | R130P | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | R130P | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | R130P | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | R130P | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | R130P | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | R130P | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | R130P | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | R130P | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | R130P | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | R130P | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | R130P | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | R130P | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | R130P | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | R130P | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| ALK | Q286Q | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | Q286Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | Q286Q | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | Q286Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | Q286Q | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | Q286Q | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | Q286Q | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | Q286Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | Q286Q | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | Q286Q | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | Q286Q | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | Q286Q | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | Q286Q | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | Q286Q | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | Q286Q | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | Q286Q | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | Q286Q | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | Q286Q | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | Q286Q | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| TP53 | G187S | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | G187S | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | G187S | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | G187S | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | G187S | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | G187S | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | G187S | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G187S | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | G187S | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | G187S | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | G187S | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | G187S | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G187S | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | G187S | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | G187S | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| KMT2A | splice_donor_variant | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | splice_donor_variant | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | splice_donor_variant | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | splice_donor_variant | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | splice_donor_variant | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | splice_donor_variant | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| KMT2A | splice_acceptor_variant | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | splice_acceptor_variant | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | splice_acceptor_variant | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | splice_acceptor_variant | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | splice_acceptor_variant | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | splice_acceptor_variant | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| TP53 | K132N | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | K132N | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | K132N | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | K132N | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | K132N | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | K132N | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | K132N | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | K132N | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | K132N | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | K132N | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | K132N | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | K132N | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | K132N | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | K132N | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | K132N | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NF1 | Q682* | Different Mutation | Vemurafenib (BRAF inhibitor) | Resistant | CM | Pre-clinical |
| NF1 | Q682* | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | HNC | Case report |
| NF1 | Q682* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q682* | Complete Match | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | Q682* | Complete Match | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Complete Match | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Complete Match | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | Q682* | Complete Match | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | Q682* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | NF | Late trials |
| NF1 | Q682* | Complete Match | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | Q682* | Complete Match | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Complete Match | Nilotinib (BCR-ABL inhibitor) | Responsive | MPN, PLEN | Pre-clinical |
| NF1 | Q682* | Complete Match | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | HNC, SG | Case report |
| NF1 | Q682* | Complete Match | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q682* | Complete Match | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | Q682* | Complete Match | MEK inhibitor | Responsive | LK, G | Pre-clinical |
| NF1 | Q682* | Complete Match | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | Q682* | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q682* | Complete Match | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Complete Match | MTOR inhibitor | Responsive | LK, G, MPN | Pre-clinical |
| NF1 | Q682* | Complete Match | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q682* | Complete Match | Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) | Responsive | HC | Case report |
| NF1 | Q682* | Complete Match | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q682* | Complete Match | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q682* | Complete Match | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | Q682* | Complete Match | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | Q682* | Complete Match | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | Q682* | Complete Match | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | Q682* | Complete Match | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q682* | Complete Match | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q682* | Complete Match | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Complete Match | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | Q682* | Complete Match | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q682* | Complete Match | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | Q682* | Different Alteration | MTOR inhibitor | Responsive | MPN, G, LK | Pre-clinical |
| NF1 | Q682* | Different Alteration | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | Q682* | Different Alteration | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q682* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | Q682* | Different Alteration | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Different Alteration | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | Q682* | Different Alteration | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q682* | Different Alteration | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | Q682* | Different Alteration | MEK inhibitor | Responsive | G, LK | Pre-clinical |
| NF1 | Q682* | Different Alteration | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | Q682* | Different Alteration | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Different Alteration | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q682* | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q682* | Different Alteration | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Different Alteration | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | Q682* | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q682* | Different Alteration | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | SG, HNC | Case report |
| NF1 | Q682* | Different Alteration | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | Q682* | Different Alteration | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q682* | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q682* | Different Alteration | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | Q682* | Different Alteration | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q682* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q682* | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | PLEN, MPN | Pre-clinical |
| NF1 | Q682* | Different Alteration | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | Q682* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | Q682* | Different Alteration | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Different Alteration | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | Q682* | Different Alteration | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | Q682* | Different Alteration | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q682* | Different Alteration | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| ROS1 | R1311Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | R1311Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | R1311Q | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | R1311Q | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | R1311Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| GATA3 | K358* | Complete Match | Aromatase ihibitor | Responsive | BRCA | Pre-clinical |
| ALK | R1275* | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | R1275* | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | R1275* | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | R1275* | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | R1275* | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | R1275* | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | R1275* | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | R1275* | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | R1275* | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | R1275* | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | R1275* | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | R1275* | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | R1275* | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | R1275* | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | R1275* | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | R1275* | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | R1275* | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | R1275* | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | R1275* | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| TP53 | T125T | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | T125T | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | T125T | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | T125T | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | T125T | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | T125T | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | T125T | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | T125T | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | T125T | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | T125T | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | T125T | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | T125T | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | T125T | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | T125T | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | T125T | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| FGFR2 | G818G | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | G818G | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| TP53 | R158G | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R158G | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R158G | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R158G | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R158G | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R158G | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R158G | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R158G | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R158G | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R158G | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R158G | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R158G | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R158G | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R158G | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R158G | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (P366R | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| NOTCH2 | S2153A | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB4 | P172R | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| RET | P117T | Different Alteration | Nintedanib (Pan-TK inhibitor) | Responsive | LUAD | Case report |
| RET | P117T | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Early trials |
| RET | P117T | Different Alteration | RET inhibitor | Responsive | LUAD | Pre-clinical |
| RET | P117T | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | P117T | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | P117T | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | THCA | Pre-clinical |
| RET | P117T | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | P117T | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | P117T | Different Alteration | RET inhibitor | Responsive | TH | Pre-clinical |
| EGFR | D916D | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | D916D | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| PTEN | splice_donor_variant | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | splice_donor_variant | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | splice_donor_variant | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | splice_donor_variant | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | splice_donor_variant | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | splice_donor_variant | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | splice_donor_variant | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | splice_donor_variant | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | splice_donor_variant | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | splice_donor_variant | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | splice_donor_variant | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | splice_donor_variant | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | splice_donor_variant | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | splice_donor_variant | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | splice_donor_variant | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | splice_donor_variant | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | splice_donor_variant | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | splice_donor_variant | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | splice_donor_variant | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | splice_donor_variant | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | splice_donor_variant | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | splice_donor_variant | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | splice_donor_variant | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | splice_donor_variant | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | splice_donor_variant | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PIK3CA | M1043I | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | M1043I | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | M1043I | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | M1043I | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | M1043I | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | M1043I | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | M1043I | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | M1043I | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | M1043I | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | M1043I | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | M1043I | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | M1043I | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | M1043I | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | M1043I | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | E286A | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | E286A | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | E286A | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | E286A | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | E286A | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | E286A | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E286A | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E286A | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E286A | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | E286A | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | E286A | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | E286A | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E286A | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | E286A | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E286A | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NOTCH1 | T1997T | Different Alteration | Gamma secretase inhibitor | Responsive | ALL | Pre-clinical |
| NOTCH1 | T1997T | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| ROS1 | N2234K | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | N2234K | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | N2234K | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | N2234K | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | N2234K | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| ERBB4 | F1004S | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| RAF1 | I122V | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | PRAD | Pre-clinical |
| RAF1 | I122V | Different Alteration | Pan-RAF inhibitor | Responsive | PRAD | Pre-clinical |
| RAF1 | I122V | Different Alteration | U0126 (MEK inhibitor) | Responsive | PRAD | Pre-clinical |
| PDGFB | intron_variant | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | DFS | FDA guidelines |
| ARID1A | Q723* | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q723* | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q723* | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | Q723* | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| KMT2A | P3059P | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | P3059P | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | P3059P | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | P3059P | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | P3059P | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | P3059P | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| EGFR | E257K | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | E257K | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| PIK3R1 | R534* | Complete Match | AKT inhibitor | Responsive | G | Pre-clinical |
| PIK3R1 | R534* | Complete Match | PI3K pathway inhibitor | Responsive | ED | Case report |
| RET | 3-UTRSNV | Different Alteration | Nintedanib (Pan-TK inhibitor) | Responsive | LUAD | Case report |
| RET | 3-UTRSNV | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Early trials |
| RET | 3-UTRSNV | Different Alteration | RET inhibitor | Responsive | LUAD | Pre-clinical |
| RET | 3-UTRSNV | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | 3-UTRSNV | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | 3-UTRSNV | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | THCA | Pre-clinical |
| RET | 3-UTRSNV | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | 3-UTRSNV | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | 3-UTRSNV | Different Alteration | RET inhibitor | Responsive | TH | Pre-clinical |
| KMT2A | S2170N), MLL MUT* (R613Q | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | S2170N), MLL MUT* (R613Q | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | S2170N), MLL MUT* (R613Q | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | S2170N), MLL MUT* (R613Q | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | S2170N), MLL MUT* (R613Q | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | S2170N), MLL MUT* (R613Q | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| NOTCH2 | A422T | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| ROS1 | 3-UTRSNV | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | 3-UTRSNV | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | 3-UTRSNV | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | 3-UTRSNV | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | 3-UTRSNV | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | L165L), ALK MUT* (P213L | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| RAF1 | 3-UTRSNV | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | PRAD | Pre-clinical |
| RAF1 | 3-UTRSNV | Different Alteration | Pan-RAF inhibitor | Responsive | PRAD | Pre-clinical |
| RAF1 | 3-UTRSNV | Different Alteration | U0126 (MEK inhibitor) | Responsive | PRAD | Pre-clinical |
| JAK2 | I77I | Different Alteration | Ruxolitinib (JAK inhibitor) | Responsive | ALL | Pre-clinical |
| MET | R412G | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | G | Case report |
| TP53 | S241C | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | S241C | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | S241C | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | S241C | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | S241C | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | S241C | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | S241C | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | S241C | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | S241C | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | S241C | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | S241C | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | S241C | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | S241C | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | S241C | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | S241C | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| BRCA1 | splice_acceptor_variant | Complete Match | Chemotherapy (PARP inhibitor;Chemotherapy) | Responsive | OV | Early trials |
| BRCA1 | splice_acceptor_variant | Complete Match | PARP inhibitor | Responsive | BRCA | Early trials |
| BRCA1 | splice_acceptor_variant | Complete Match | PARP inhibitor;Chemotherapy | Responsive | OV | Early trials |
| BRCA1 | splice_acceptor_variant | Complete Match | Rucaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | splice_acceptor_variant | Complete Match | Platinum Agent (Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | splice_acceptor_variant | Complete Match | WEE1 inhibitor | Responsive | CANCER | Case report |
| BRCA1 | splice_acceptor_variant | Complete Match | Platinum Agent (Chemotherapy) | Responsive | OV | Late trials |
| BRCA1 | splice_acceptor_variant | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| BRCA1 | splice_acceptor_variant | Complete Match | Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | splice_acceptor_variant | Complete Match | PARP inhibitor | Responsive | PA | Case report |
| BRCA1 | splice_acceptor_variant | Complete Match | Olaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | splice_acceptor_variant | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| AKT3 | R66* | Different Alteration | ATP competitive AKT inhibitor | Responsive | BRCA | Pre-clinical |
| ARID1A | Q548* | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q548* | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q548* | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | Q548* | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| ERBB4 | L1008L | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| SF3B1 | K666E | Different Mutation | Spliceosome inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C135W | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C135W | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C135W | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C135W | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C135W | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C135W | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C135W | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C135W | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C135W | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C135W | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C135W | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C135W | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C135W | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C135W | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C135W | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | G1007R | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | G1007R | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | G1007R | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | G1007R | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | G1007R | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | G1007R | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | G1007R | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | G1007R | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | G1007R | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | G1007R | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | G1007R | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | G1007R | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | G1007R | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | G1007R | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| NOTCH2 | R1630H | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| NOTCH1 | Q2487L | Different Alteration | Gamma secretase inhibitor | Responsive | ALL | Pre-clinical |
| NOTCH1 | Q2487L | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| TP53 | E56* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | E56* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | E56* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | E56* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | E56* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | E56* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E56* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E56* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E56* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | E56* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | E56* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | E56* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E56* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | E56* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E56* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (Q546K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| PIK3CA | E1037K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E1037K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E1037K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E1037K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E1037K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E1037K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E1037K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E1037K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E1037K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E1037K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E1037K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E1037K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E1037K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E1037K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| NOTCH2 | L1717I | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| ROS1 | S551F | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | S551F | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | S551F | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | S551F | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | S551F | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| ROS1 | R1910* | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | R1910* | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | R1910* | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | R1910* | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | R1910* | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| TP53 | R280T | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R280T | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R280T | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R280T | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R280T | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R280T | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R280T | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R280T | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R280T | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R280T | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R280T | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R280T | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R280T | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R280T | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R280T | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| RB1 | Q93* | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | Q93* | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | Q93* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | Q93* | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | Q93* | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | Q93* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | Q93* | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| IDH1 | R132C | Complete Match | Venetoclax (BCL2 inhibitor) | Responsive | AML | Early trials |
| IDH1 | R132C | Complete Match | IDH1 inhibitor | Responsive | AML | Early trials |
| IDH1 | R132C | Complete Match | AG-120 (IDH1 inhibitor) | Responsive | G | Early trials |
| IDH1 | R132C | Complete Match | Dasatinib (BCR-ABL inhibitor) | Responsive | CH | Early trials |
| IDH1 | R132C | Complete Match | Ivosidenib (IDH1 inhibitor) | Responsive | AML | Early trials |
| IDH1 | R132C | Complete Match | BCL2 inhibitor | Responsive | AML | Pre-clinical |
| IDH1 | R132C | Complete Match | BCL2 inhibitor (BCL2 inhibitor) | Responsive | AML | Pre-clinical |
| IDH1 | R132C | Complete Match | Dasatinib (BCR-ABL inhibitor) | Responsive | BT | Pre-clinical |
| IDH1 | R132C | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| PTEN | N48I | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | N48I | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | N48I | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | N48I | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | N48I | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | N48I | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | N48I | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | N48I | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | N48I | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | N48I | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | N48I | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | N48I | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | N48I | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | N48I | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | N48I | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | N48I | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | N48I | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | N48I | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | N48I | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | N48I | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | N48I | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | N48I | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | N48I | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | N48I | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | N48I | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| ESR1 | L370F | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| BCR | E771Q | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| BCR | E771Q | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| BCR | E771Q | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | E771Q | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | E771Q | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| BCR | E771Q | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (E365V | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| PIK3R1 | I559T | Complete Match | AKT inhibitor | Responsive | G | Pre-clinical |
| PIK3R1 | I559T | Complete Match | PI3K pathway inhibitor | Responsive | ED | Case report |
| TP53 | V173L | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | V173L | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | V173L | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | V173L | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | V173L | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | V173L | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | V173L | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V173L | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V173L | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | V173L | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | V173L | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | V173L | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V173L | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | V173L | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V173L | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | K111E | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | K111E | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | K111E | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | K111E | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | K111E | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | K111E | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | K111E | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | K111E | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | K111E | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | K111E | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | K111E | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | K111E | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | K111E | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | K111E | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | N247I | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | N247I | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | N247I | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | N247I | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | N247I | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | N247I | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | N247I | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | N247I | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | N247I | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | N247I | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | N247I | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | N247I | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | N247I | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | N247I | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | N247I | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ERBB2 | D769Y | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | D769Y | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | D769Y | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, BRCA, GEJA | FDA guidelines |
| ERBB2 | D769Y | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | D769Y | Different Alteration | MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) | Responsive | SOLID | Early trials |
| ERBB2 | D769Y | Complete Match | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769Y | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769Y | Complete Match | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER, BRCA | Pre-clinical |
| ERBB2 | D769Y | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | D769Y | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Case report |
| ERBB2 | D769Y | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA, LUAD | Case report |
| ERBB2 | D769Y | Different Mutation | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | L | Early trials |
| ERBB2 | D769Y | Different Mutation | Neratinib (ERBB2 inhibitor) | Resistant | BRCA | Case report |
| ERBB2 | D769Y | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769Y | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Case report |
| ERBB2 | D769Y | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769Y | Different Mutation | Lapatinib (ERBB2 inhibitor) | Resistant | BRCA | Pre-clinical |
| ERBB2 | D769Y | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB2 | D769Y | Complete Match | Temsirolimus (MTOR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769Y | Complete Match | Dacomitinib (Pan ERBB inhibitor) | Responsive | NSCLC | Early trials |
| ERBB2 | D769Y | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769Y | Different Mutation | ERBB2 inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | D769Y | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769Y | Different Mutation | ERBB2 mAb inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | D769Y | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769Y | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769Y | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769Y | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | D769Y | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | D769Y | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | COREAD | Late trials |
| ERBB2 | D769Y | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | OV | Early trials |
| ERBB2 | D769Y | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB2 | D769Y | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | COREAD | Case report |
| ERBB2 | D769Y | Different Alteration | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | D769Y | Different Alteration | Osimertinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | D769Y | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | D769Y | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| ERBB2 | D769Y | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BT | Early trials |
| ERBB2 | D769Y | Different Alteration | Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) | Responsive | BRCA | Early trials |
| ERBB2 | D769Y | Different Alteration | HER2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769Y | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | D769Y | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | ST | Early trials |
| ERBB2 | D769Y | Different Alteration | Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| ERBB2 | D769Y | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, GEJA | FDA guidelines |
| ERBB2 | D769Y | Different Alteration | ERBB2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769Y | Different Alteration | Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | D769Y | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | HNC | Case report |
| ERBB2 | D769Y | Different Alteration | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | D769Y | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | No Responsive | ED | Early trials |
| ERBB2 | D769Y | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | ED | Pre-clinical |
| ERBB2 | D769Y | Different Alteration | Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) | Responsive | ST | Early trials |
| ERBB2 | D769Y | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | ST | Case report |
| ERBB2 | D769Y | Different Alteration | EGFR inhibitor | Resistant | LUAD | Pre-clinical |
| TP53 | Y126C | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Y126C | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Y126C | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Y126C | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Y126C | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Y126C | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Y126C | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y126C | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y126C | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Y126C | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Y126C | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Y126C | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y126C | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Y126C | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y126C | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C238F | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C238F | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C238F | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C238F | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C238F | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C238F | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C238F | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C238F | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C238F | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C238F | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C238F | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C238F | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C238F | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C238F | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C238F | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | S127P | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | S127P | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | S127P | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | S127P | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | S127P | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | S127P | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | S127P | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | S127P | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | S127P | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | S127P | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | S127P | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | S127P | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | S127P | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | S127P | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | S127P | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| LRP1B | Q400* | Complete Match | Liposomal Doxorubicin (Chemotherapy) | Resistant | OV | Early trials |
| LRP1B | Q400* | Different Alteration | Liposomal Doxorubicin (Chemotherapy) | Resistant | OV | Early trials |
| ROS1 | S2326F | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | S2326F | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | S2326F | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | S2326F | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | S2326F | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| NOTCH2 | S801L | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | S287* | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | S287* | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | S287* | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | S287* | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | S287* | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | S287* | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | S287* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | S287* | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | S287* | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | S287* | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | S287* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | S287* | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | S287* | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | S287* | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | S287* | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | S287* | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | S287* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | S287* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | S287* | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | S287* | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | S287* | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | S287* | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | S287* | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | S287* | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | S287* | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| TP53 | Y205N | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Y205N | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Y205N | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Y205N | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Y205N | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Y205N | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Y205N | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y205N | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y205N | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Y205N | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Y205N | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Y205N | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y205N | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Y205N | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y205N | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NOTCH2 | Y217F | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| BRAF | E309* | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | CM, LUAD, PRAD | Pre-clinical |
| BRAF | E309* | Different Alteration | MEK inhibitor | Responsive | LUAD, CM, PRAD | Pre-clinical |
| BRAF | E309* | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | OV | Case report |
| BRAF | E309* | Different Alteration | BRAF inhibitor;MEK inhibitor | Responsive | LUAD | Case report |
| ERBB4 | intron_variant | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| PTEN | L146* | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | L146* | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | L146* | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | L146* | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | L146* | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | L146* | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | L146* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | L146* | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | L146* | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | L146* | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | L146* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | L146* | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | L146* | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | L146* | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | L146* | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | L146* | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | L146* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | L146* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | L146* | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | L146* | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | L146* | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | L146* | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | L146* | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | L146* | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | L146* | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| TP53 | H193Y | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | H193Y | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | H193Y | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | H193Y | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | H193Y | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | H193Y | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | H193Y | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H193Y | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H193Y | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | H193Y | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | H193Y | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | H193Y | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H193Y | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | H193Y | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H193Y | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ALK | L1169L | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | L1169L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | L1169L | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | L1169L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | L1169L | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | L1169L | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | L1169L | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | L1169L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | L1169L | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | L1169L | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | L1169L | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | L1169L | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | L1169L | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | L1169L | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | L1169L | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | L1169L | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | L1169L | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | L1169L | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | L1169L | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| ALK | L1048L | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | L1048L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | L1048L | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | L1048L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | L1048L | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | L1048L | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | L1048L | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | L1048L | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | L1048L | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | L1048L | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | L1048L | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | L1048L | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | L1048L | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | L1048L | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | L1048L | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | L1048L | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | L1048L | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | L1048L | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | L1048L | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| ERBB2 | D769H | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | D769H | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | D769H | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, BRCA, GEJA | FDA guidelines |
| ERBB2 | D769H | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | D769H | Different Alteration | MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) | Responsive | SOLID | Early trials |
| ERBB2 | D769H | Complete Match | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769H | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769H | Complete Match | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER, BRCA | Pre-clinical |
| ERBB2 | D769H | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | D769H | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Case report |
| ERBB2 | D769H | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA, LUAD | Case report |
| ERBB2 | D769H | Different Mutation | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | L | Early trials |
| ERBB2 | D769H | Different Mutation | Neratinib (ERBB2 inhibitor) | Resistant | BRCA | Case report |
| ERBB2 | D769H | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769H | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Case report |
| ERBB2 | D769H | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769H | Different Mutation | Lapatinib (ERBB2 inhibitor) | Resistant | BRCA | Pre-clinical |
| ERBB2 | D769H | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB2 | D769H | Complete Match | Temsirolimus (MTOR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769H | Complete Match | Dacomitinib (Pan ERBB inhibitor) | Responsive | NSCLC | Early trials |
| ERBB2 | D769H | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769H | Different Mutation | ERBB2 inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | D769H | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769H | Different Mutation | ERBB2 mAb inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | D769H | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769H | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769H | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | D769H | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | D769H | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | D769H | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | COREAD | Late trials |
| ERBB2 | D769H | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | OV | Early trials |
| ERBB2 | D769H | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB2 | D769H | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | COREAD | Case report |
| ERBB2 | D769H | Different Alteration | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | D769H | Different Alteration | Osimertinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | D769H | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | D769H | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| ERBB2 | D769H | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BT | Early trials |
| ERBB2 | D769H | Different Alteration | Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) | Responsive | BRCA | Early trials |
| ERBB2 | D769H | Different Alteration | HER2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769H | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | D769H | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | ST | Early trials |
| ERBB2 | D769H | Different Alteration | Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| ERBB2 | D769H | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, GEJA | FDA guidelines |
| ERBB2 | D769H | Different Alteration | ERBB2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | D769H | Different Alteration | Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | D769H | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | HNC | Case report |
| ERBB2 | D769H | Different Alteration | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | D769H | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | No Responsive | ED | Early trials |
| ERBB2 | D769H | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | ED | Pre-clinical |
| ERBB2 | D769H | Different Alteration | Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) | Responsive | ST | Early trials |
| ERBB2 | D769H | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | ST | Case report |
| ERBB2 | D769H | Different Alteration | EGFR inhibitor | Resistant | LUAD | Pre-clinical |
| RET | L1101V | Different Alteration | Nintedanib (Pan-TK inhibitor) | Responsive | LUAD | Case report |
| RET | L1101V | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Early trials |
| RET | L1101V | Different Alteration | RET inhibitor | Responsive | LUAD | Pre-clinical |
| RET | L1101V | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | L1101V | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | L1101V | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | THCA | Pre-clinical |
| RET | L1101V | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | L1101V | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | L1101V | Different Alteration | RET inhibitor | Responsive | TH | Pre-clinical |
| ERCC4 | E359* | Complete Match | Cisplatin (Chemotherapy) | Responsive | OV | Pre-clinical |
| JAK2 | R138P | Different Alteration | Ruxolitinib (JAK inhibitor) | Responsive | ALL | Pre-clinical |
| RB1 | C853* | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | C853* | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | C853* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | C853* | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | C853* | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | C853* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | C853* | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| TP53 | L194P | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | L194P | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | L194P | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | L194P | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | L194P | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | L194P | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | L194P | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L194P | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L194P | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | L194P | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | L194P | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | L194P | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L194P | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | L194P | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L194P | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | H179Y | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | H179Y | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | H179Y | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | H179Y | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | H179Y | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | H179Y | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | H179Y | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H179Y | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H179Y | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | H179Y | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | H179Y | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | H179Y | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H179Y | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | H179Y | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H179Y | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C141R | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C141R | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C141R | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C141R | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C141R | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C141R | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C141R | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C141R | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C141R | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C141R | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C141R | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C141R | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C141R | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C141R | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C141R | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| EGFR | T847K | Different Alteration | Cetuximab (EGFR mAb inhibitor) | Responsive | COREAD | FDA guidelines |
| EGFR | T847K | Different Alteration | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | FDA guidelines |
| EGFR | T847K | Different Mutation | Rindopepimut (Vaccine) | Responsive | GB | Late trials |
| EGFR | T847K | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | T847K | Different Mutation | Gefitinib (EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | T847K | Different Mutation | HSP90 inhibitor | Responsive | L | Early trials |
| EGFR | T847K | Different Mutation | Afatinib;Cetuximab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) | Responsive | L | Early trials |
| EGFR | T847K | Different Mutation | MEK inhibitor | Responsive | L | Pre-clinical |
| EGFR | T847K | Different Mutation | EGFR TK inhibitor | Responsive | L | Late trials |
| EGFR | T847K | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | NCCN guidelines |
| EGFR | T847K | Different Mutation | Osimertinib (EGFR inhibitor) | Resistant | L | Early trials |
| EGFR | T847K | Different Mutation | EGFR-TKI's (EGFR inhibitor) | Resistant | L | Late trials |
| EGFR | T847K | Different Mutation | HSP90 inhibitor | Responsive | L | Case report |
| EGFR | T847K | Different Mutation | EGFR inhibitor | Resistant | L | Late trials |
| EGFR | T847K | Different Mutation | Poziotinib (EGFR inhibitor) | Responsive | L | Early trials |
| EGFR | T847K | Different Mutation | Osimertinib (EGFR inhibitor) | Responsive | L | Pre-clinical |
| EGFR | T847K | Different Mutation | HSP90 inhibitor (HSP90 inhibitor) | Responsive | L | Early trials |
| EGFR | T847K | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | G | Pre-clinical |
| EGFR | T847K | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | T847K | Different Mutation | Osimertinib (EGFR inhibitor) | Responsive | L | Early trials |
| EGFR | T847K | Different Mutation | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| EGFR | T847K | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Responsive | COREAD | Case report |
| EGFR | T847K | Different Mutation | novel EGFR mAb inhibitor | Responsive | COREAD | Early trials |
| EGFR | T847K | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| EGFR | T847K | Different Mutation | Cetuximab;Sirolimus (EGFR mAb inhibitor;MTOR inhibitor) | Responsive | HNC | Case report |
| EGFR | T847K | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | T847K | Different Mutation | Gefitinib (EGFR inhibitor) | No Responsive | HNC | Case report |
| EGFR | T847K | Different Mutation | EGFR inhibitor | Responsive | L | Early trials |
| EGFR | T847K | Different Mutation | Erlotinib (EGFR inhibitor) | Resistant | L | NCCN/CAP guidelines |
| EGFR | T847K | Different Mutation | Osimertinib (EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | T847K | Different Mutation | EGFR inhibitor | Responsive | NSCLC | Late trials |
| EGFR | T847K | Different Mutation | Afatinib;Nimotuzumab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) | Responsive | L | Early trials |
| EGFR | T847K | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Resistant | L | NCCN/CAP guidelines |
| EGFR | T847K | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | L | Early trials |
| EGFR | T847K | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | L | Late trials |
| EGFR | T847K | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Pre-clinical |
| EGFR | T847K | Different Mutation | Erlotinib (EGFR inhibitor) | No Responsive | L | Case report |
| EGFR | T847K | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | ED | Case report |
| EGFR | T847K | Different Mutation | EGFR inhibitor | No Responsive | G | Early trials |
| EGFR | T847K | Different Mutation | EGFR inhibitor | Resistant | NSCLC | Case report |
| EGFR | T847K | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| EGFR | T847K | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant;Resistant | COREAD | Pre-clinical;Case report |
| EGFR | T847K | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Responsive | HNC | Case report |
| EGFR | T847K | Different Alteration | Gefitinib (EGFR inhibitor) | Responsive | ED | Late trials |
| EGFR | T847K | Different Alteration | Gefitinib (EGFR inhibitor) | No Responsive | HNC | Early trials |
| EGFR | T847K | Different Alteration | EGFR inhibitor | Responsive | HNSC | Case report |
| EGFR | T847K | Different Alteration | EGFR inhibitor | No Responsive | G | Early trials |
| EGFR | T847K | Different Alteration | Erlotinib (EGFR inhibitor) | No Responsive | L | Early trials |
| EGFR | T847K | Different Alteration | EGFR mAb inhibitor | Responsive | COREAD | Late trials |
| EGFR | T847K | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | T847K | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| ERBB2 | I767M | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | I767M | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | I767M | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, BRCA, GEJA | FDA guidelines |
| ERBB2 | I767M | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | I767M | Different Alteration | MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) | Responsive | SOLID | Early trials |
| ERBB2 | I767M | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | I767M | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | I767M | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER, BRCA | Pre-clinical |
| ERBB2 | I767M | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | CANCER | Early trials |
| ERBB2 | I767M | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Case report |
| ERBB2 | I767M | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | BRCA, LUAD | Case report |
| ERBB2 | I767M | Different Mutation | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | L | Early trials |
| ERBB2 | I767M | Different Mutation | Neratinib (ERBB2 inhibitor) | Resistant | BRCA | Case report |
| ERBB2 | I767M | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Pre-clinical |
| ERBB2 | I767M | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Case report |
| ERBB2 | I767M | Different Mutation | Lapatinib (ERBB2 inhibitor) | Resistant | BRCA | Pre-clinical |
| ERBB2 | I767M | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | CANCER | Pre-clinical |
| ERBB2 | I767M | Complete Match | Temsirolimus (MTOR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | I767M | Complete Match | Dacomitinib (Pan ERBB inhibitor) | Responsive | NSCLC | Early trials |
| ERBB2 | I767M | Complete Match | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | I767M | Different Mutation | ERBB2 inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | I767M | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | I767M | Different Mutation | ERBB2 mAb inhibitor | Responsive | LUAD | Early trials |
| ERBB2 | I767M | Different Mutation | Neratinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | I767M | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | I767M | Different Mutation | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | LUAD | Early trials |
| ERBB2 | I767M | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | I767M | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | I767M | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | COREAD | Late trials |
| ERBB2 | I767M | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | OV | Early trials |
| ERBB2 | I767M | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | BLCA | Case report |
| ERBB2 | I767M | Different Alteration | Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) | Responsive | COREAD | Case report |
| ERBB2 | I767M | Different Alteration | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | I767M | Different Alteration | Osimertinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| ERBB2 | I767M | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BT | Early trials |
| ERBB2 | I767M | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Early trials |
| ERBB2 | I767M | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | BT | Early trials |
| ERBB2 | I767M | Different Alteration | Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) | Responsive | BRCA | Early trials |
| ERBB2 | I767M | Different Alteration | HER2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | I767M | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | I767M | Different Alteration | Pertuzumab (ERBB2 mAb inhibitor) | Responsive | ST | Early trials |
| ERBB2 | I767M | Different Alteration | Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| ERBB2 | I767M | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | ST, GEJA | FDA guidelines |
| ERBB2 | I767M | Different Alteration | ERBB2 inhibitor;CDK4/6 inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB2 | I767M | Different Alteration | Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) | Responsive | BRCA | FDA guidelines |
| ERBB2 | I767M | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | Responsive | HNC | Case report |
| ERBB2 | I767M | Different Alteration | Neratinib (ERBB2 inhibitor) | Responsive | BRCA | Late trials |
| ERBB2 | I767M | Different Alteration | Trastuzumab (ERBB2 mAb inhibitor) | No Responsive | ED | Early trials |
| ERBB2 | I767M | Different Alteration | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Responsive | ED | Pre-clinical |
| ERBB2 | I767M | Different Alteration | Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) | Responsive | ST | Early trials |
| ERBB2 | I767M | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | ST | Case report |
| ERBB2 | I767M | Different Alteration | EGFR inhibitor | Resistant | LUAD | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | H1047R), PIK3CA MUT (R108H | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | H168P | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | H168P | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | H168P | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | H168P | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | H168P | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | H168P | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | H168P | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H168P | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H168P | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | H168P | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | H168P | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | H168P | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H168P | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | H168P | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H168P | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Q136* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Q136* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Q136* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Q136* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Q136* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Q136* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Q136* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q136* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q136* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Q136* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Q136* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Q136* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q136* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Q136* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q136* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| KMT2A | S1002C | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | S1002C | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | S1002C | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | S1002C | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | S1002C | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | S1002C | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| ARID1A | Q528* | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q528* | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q528* | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | Q528* | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| ESR1 | Y246* | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| TP53 | R280* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R280* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R280* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R280* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R280* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R280* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R280* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R280* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R280* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R280* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R280* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R280* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R280* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R280* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R280* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| FLCN | S333* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | R | Case report |
| FLCN | S333* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | TH | Case report |
| TP53 | I232S | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | I232S | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | I232S | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | I232S | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | I232S | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | I232S | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | I232S | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | I232S | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | I232S | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | I232S | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | I232S | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | I232S | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | I232S | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | I232S | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | I232S | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ESR1 | G274G | Different Alteration | ESR1 inhibitor | Resistant | BRCA | Pre-clinical |
| NTRK1 | R583H | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Case report |
| NTRK1 | R583H | Different Alteration | Pan-TKR inhibitor | Responsive | CANCER | Early trials |
| NTRK1 | R583H | Different Alteration | Pan-TK inhibitor | Responsive | LUAD | Pre-clinical |
| NTRK1 | R583H | Different Alteration | Pan-TK inhibitor | Responsive | COREAD | Case report |
| NOTCH2 | E1780K | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| ERBB4 | E317E | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| PTEN | C124G | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | C124G | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | C124G | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | C124G | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | C124G | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | C124G | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | C124G | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | C124G | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | C124G | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | C124G | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | C124G | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | C124G | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | C124G | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | C124G | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | C124G | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | C124G | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | C124G | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | C124G | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | C124G | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | C124G | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | C124G | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | C124G | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | C124G | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | C124G | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | C124G | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| RET | L846I | Different Alteration | Nintedanib (Pan-TK inhibitor) | Responsive | LUAD | Case report |
| RET | L846I | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Early trials |
| RET | L846I | Different Alteration | RET inhibitor | Responsive | LUAD | Pre-clinical |
| RET | L846I | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | L846I | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | L846I | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | THCA | Pre-clinical |
| RET | L846I | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | L846I | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | L846I | Different Alteration | RET inhibitor | Responsive | TH | Pre-clinical |
| KMT2A | T1842A | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | T1842A | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | T1842A | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | T1842A | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | T1842A | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | T1842A | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| JAK2 | splice_acceptor_variant | Different Alteration | Ruxolitinib (JAK inhibitor) | Responsive | ALL | Pre-clinical |
| ROS1 | S932T | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | S932T | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | S932T | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | S932T | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | S932T | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| ERBB4 | Y1022C | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| TP53 | P278A | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | P278A | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | P278A | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | P278A | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | P278A | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | P278A | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | P278A | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P278A | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | P278A | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | P278A | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | P278A | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | P278A | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P278A | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | P278A | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | P278A | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | V344M | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | V344M | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | V344M | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | V344M | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | V344M | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | V344M | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | V344M | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | V344M | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | V344M | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | V344M | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | V344M | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | V344M | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | V344M | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | V344M | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| NOTCH2 | V2469I | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| NRG1 | intron_variant | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Pre-clinical |
| NRG1 | intron_variant | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Case report |
| DNMT3A | G890D | Complete Match | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| RB1 | splice_acceptor_variant | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | splice_acceptor_variant | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | splice_acceptor_variant | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | splice_acceptor_variant | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | splice_acceptor_variant | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | splice_acceptor_variant | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | splice_acceptor_variant | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| ROS1 | W1694* | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | W1694* | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | W1694* | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | W1694* | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | W1694* | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| PDGFRA | D1075N | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | MDPS, MDS, ECL, HES | FDA guidelines |
| NTRK3 | A573V | Different Alteration | IGF1R inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | A573V | Different Alteration | PI3K pathway inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | A573V | Different Alteration | Midostaurin (Pan-TK inhibitor) | Responsive | BRCA | Pre-clinical |
| STK11 | Q123* | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | PA | Case report |
| STK11 | Q123* | Complete Match | Phenformin (Anti-diabetic) | Responsive | LUAD | Pre-clinical |
| STK11 | Q123* | Complete Match | MTOR inhibitor | Responsive | CANCER | Pre-clinical |
| STK11 | Q123* | Complete Match | BET inhibitor | Resistant | L | Pre-clinical |
| STK11 | Q123* | Complete Match | PD1 inhibitor | Resistant | CANCER | Early trials |
| STK11 | Q123* | Complete Match | SRC inhibitor;PI3K/MEK inhibitor | Responsive | LUAD | Pre-clinical |
| STK11 | Q123* | Complete Match | MEK inhibitor | Responsive | LUAD | Pre-clinical |
| STK11 | Q123* | Different Alteration | MTOR inhibitor | Responsive | CANCER | Pre-clinical |
| STK11 | Q123* | Different Alteration | PD1 inhibitor | Resistant | CANCER | Early trials |
| STK11 | Q123* | Different Alteration | Phenformin (Anti-diabetic) | Responsive | LUAD | Pre-clinical |
| STK11 | Q123* | Different Alteration | MEK inhibitor | Responsive | LUAD | Pre-clinical |
| STK11 | Q123* | Different Alteration | SRC inhibitor;PI3K/MEK inhibitor | Responsive | LUAD | Pre-clinical |
| JAK2 | C75F | Different Alteration | Ruxolitinib (JAK inhibitor) | Responsive | ALL | Pre-clinical |
| FGFR2 | E367Q | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | E367Q | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| RET | I625M | Different Alteration | Nintedanib (Pan-TK inhibitor) | Responsive | LUAD | Case report |
| RET | I625M | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Early trials |
| RET | I625M | Different Alteration | RET inhibitor | Responsive | LUAD | Pre-clinical |
| RET | I625M | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | I625M | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | I625M | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | THCA | Pre-clinical |
| RET | I625M | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | I625M | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | I625M | Different Alteration | RET inhibitor | Responsive | TH | Pre-clinical |
| PML | P410A | Different Alteration | Volasertib (PLK1 inhibitor) | Responsive | AML | Early trials |
| PML | P410A | Different Alteration | Tretinoin (Retinoid) | Responsive | APML | FDA guidelines |
| PML | P410A | Different Alteration | Tretinoin;Arsenic Trioxide (Retinoid;Chemotherapy) | Responsive | AML | FDA guidelines |
| SETD2 | S618* | Complete Match | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| SETD2 | S618* | Different Alteration | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R306* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R306* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R306* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R306* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R306* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R306* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R306* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R306* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R306* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R306* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R306* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R306* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R306* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R306* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R306* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | A276P | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | A276P | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | A276P | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | A276P | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | A276P | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | A276P | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | A276P | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | A276P | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | A276P | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | A276P | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | A276P | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | A276P | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | A276P | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | A276P | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | A276P | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NF1 | Q347* | Different Mutation | Vemurafenib (BRAF inhibitor) | Resistant | CM | Pre-clinical |
| NF1 | Q347* | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | HNC | Case report |
| NF1 | Q347* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q347* | Complete Match | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | Q347* | Complete Match | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Complete Match | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Complete Match | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | Q347* | Complete Match | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | Q347* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | NF | Late trials |
| NF1 | Q347* | Complete Match | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | Q347* | Complete Match | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Complete Match | Nilotinib (BCR-ABL inhibitor) | Responsive | MPN, PLEN | Pre-clinical |
| NF1 | Q347* | Complete Match | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | HNC, SG | Case report |
| NF1 | Q347* | Complete Match | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q347* | Complete Match | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | Q347* | Complete Match | MEK inhibitor | Responsive | LK, G | Pre-clinical |
| NF1 | Q347* | Complete Match | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | Q347* | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q347* | Complete Match | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Complete Match | MTOR inhibitor | Responsive | LK, G, MPN | Pre-clinical |
| NF1 | Q347* | Complete Match | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q347* | Complete Match | Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) | Responsive | HC | Case report |
| NF1 | Q347* | Complete Match | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q347* | Complete Match | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q347* | Complete Match | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | Q347* | Complete Match | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | Q347* | Complete Match | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | Q347* | Complete Match | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | Q347* | Complete Match | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q347* | Complete Match | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q347* | Complete Match | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Complete Match | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | Q347* | Complete Match | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q347* | Complete Match | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | Q347* | Different Alteration | MTOR inhibitor | Responsive | MPN, G, LK | Pre-clinical |
| NF1 | Q347* | Different Alteration | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | Q347* | Different Alteration | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q347* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | Q347* | Different Alteration | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Different Alteration | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | Q347* | Different Alteration | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q347* | Different Alteration | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | Q347* | Different Alteration | MEK inhibitor | Responsive | G, LK | Pre-clinical |
| NF1 | Q347* | Different Alteration | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | Q347* | Different Alteration | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Different Alteration | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q347* | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | Q347* | Different Alteration | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Different Alteration | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | Q347* | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q347* | Different Alteration | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | SG, HNC | Case report |
| NF1 | Q347* | Different Alteration | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | Q347* | Different Alteration | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | Q347* | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q347* | Different Alteration | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | Q347* | Different Alteration | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | Q347* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | Q347* | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | PLEN, MPN | Pre-clinical |
| NF1 | Q347* | Different Alteration | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | Q347* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | Q347* | Different Alteration | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Different Alteration | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | Q347* | Different Alteration | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | Q347* | Different Alteration | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | Q347* | Different Alteration | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| EPHA3 | splice_donor_variant | Different Alteration | EPHA3 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R282G | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R282G | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R282G | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R282G | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R282G | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R282G | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R282G | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R282G | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R282G | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R282G | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R282G | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R282G | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R282G | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R282G | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R282G | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PIK3CA | K111N | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | K111N | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | K111N | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | K111N | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | K111N | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | K111N | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | K111N | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | K111N | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | K111N | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | K111N | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | K111N | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | K111N | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | K111N | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | K111N | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| PIK3CA | M1004I | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | M1004I | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | M1004I | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | M1004I | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | M1004I | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | M1004I | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | M1004I | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | M1004I | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | M1004I | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | M1004I | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | M1004I | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | M1004I | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | M1004I | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | M1004I | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| EGFR | R958R | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | R958R | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| TP53 | Q167* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Q167* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Q167* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Q167* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Q167* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Q167* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Q167* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q167* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q167* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Q167* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Q167* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Q167* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q167* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Q167* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q167* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| CDH1 | T379T | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| ROS1 | T1735T | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | T1735T | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | T1735T | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | T1735T | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | T1735T | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| NOTCH1 | A2036V | Different Alteration | Gamma secretase inhibitor | Responsive | ALL | Pre-clinical |
| NOTCH1 | A2036V | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| TP53 | Y126N | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Y126N | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Y126N | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Y126N | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Y126N | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Y126N | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Y126N | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y126N | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Y126N | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Y126N | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Y126N | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Y126N | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y126N | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Y126N | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Y126N | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | V157F | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | V157F | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | V157F | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | V157F | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | V157F | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | V157F | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | V157F | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V157F | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V157F | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | V157F | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | V157F | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | V157F | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V157F | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | V157F | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V157F | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ROS1 | P1743Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | P1743Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | P1743Q | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | P1743Q | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | P1743Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| NRG1 | 5-UTRSNV | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Pre-clinical |
| NRG1 | 5-UTRSNV | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Case report |
| BRAF | E433K | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | CM, LUAD, PRAD | Pre-clinical |
| BRAF | E433K | Different Alteration | MEK inhibitor | Responsive | LUAD, CM, PRAD | Pre-clinical |
| BRAF | E433K | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | OV | Case report |
| BRAF | E433K | Different Alteration | BRAF inhibitor;MEK inhibitor | Responsive | LUAD | Case report |
| NTRK3 | R306P | Different Alteration | IGF1R inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | R306P | Different Alteration | PI3K pathway inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | R306P | Different Alteration | Midostaurin (Pan-TK inhibitor) | Responsive | BRCA | Pre-clinical |
| NOTCH2 | H151Y | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| KMT2A | I3288I | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | I3288I | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | I3288I | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | I3288I | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | I3288I | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | I3288I | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| PDGFRA | E556K | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | MDPS, MDS, ECL, HES | FDA guidelines |
| PTPRD | Q193* | Complete Match | IGF1R inhibitor | Responsive | S | Case report |
| ALK | E576Q | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | E576Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | E576Q | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | E576Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | E576Q | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | E576Q | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | E576Q | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | E576Q | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | E576Q | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | E576Q | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | E576Q | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | E576Q | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | E576Q | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | E576Q | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | E576Q | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | E576Q | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | E576Q | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | E576Q | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | E576Q | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| SETD2 | S815* | Complete Match | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| SETD2 | S815* | Different Alteration | WEE1 inhibitor | Responsive | CANCER | Pre-clinical |
| CDKN1B | splice_acceptor_variant | Complete Match | CDK2/4 inhibitor | Responsive | CANCER | Pre-clinical |
| CDKN1B | splice_acceptor_variant | Different Alteration | CDK2/4 inhibitor | Responsive | CANCER | Pre-clinical |
| MSH2 | R621* | Complete Match | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| MSH2 | R621* | Different Alteration | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| KMT2A | K1185K | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | K1185K | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | K1185K | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | K1185K | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | K1185K | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | K1185K | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| PIK3CA | N1044Y | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | N1044Y | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | N1044Y | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | N1044Y | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | N1044Y | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | N1044Y | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | N1044Y | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | N1044Y | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | N1044Y | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | N1044Y | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | N1044Y | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | N1044Y | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | N1044Y | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | N1044Y | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| KRAS | G12D | Complete Match | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | FDA guidelines |
| KRAS | G12D | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | FDA guidelines |
| KRAS | G12D | Different Mutation | Cetuximab (EGFR mAb inhibitor) | No Responsive | COREAD | Late trials |
| KRAS | G12D | Complete Match | MEK inhibitor | Responsive | ALL | Pre-clinical |
| KRAS | G12D | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Resistant | GIST | Case report |
| KRAS | G12D | Complete Match | MEK inhibitor | Responsive | OV, CER, AML | Pre-clinical |
| KRAS | G12D | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Responsive | L | Early trials |
| KRAS | G12D | Complete Match | MEK inhibitor;PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12D | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | NCCN guidelines |
| KRAS | G12D | Complete Match | Sorafenib;MEK inhibitor (Pan-TK inhibitor;MEK inhibitor) | Responsive | HC | Early trials |
| KRAS | G12D | Complete Match | EGFR inhibitor | Resistant | L | NCCN guidelines |
| KRAS | G12D | Complete Match | CDK4 inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12D | Complete Match | Selumetinib (MEK inhibitor) | Responsive | NSCLC | Early trials |
| KRAS | G12D | Complete Match | BET inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12D | Complete Match | Decitabine;BCL2 inhibitor (Chemotherapy;BCL2 inhibitor) | Responsive | OV | Pre-clinical |
| KRAS | G12D | Complete Match | FAK inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12D | Complete Match | EGFR inhibitor | Resistant | NSCLC | Pre-clinical |
| KRAS | G12D | Complete Match | EZH2 inhibitor | Resistant | CANCER | Pre-clinical |
| KRAS | G12D | Complete Match | MEK inhibitor | Responsive | BT, L | Early trials |
| KRAS | G12D | Complete Match | MEK inhibitor;IGF1R inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12D | Complete Match | MTOR inhibitor;BH3 mimetics | Responsive | COREAD | Pre-clinical |
| KRAS | G12D | Complete Match | EGFR mAb inhibitor;MEK inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12D | Complete Match | pan-RAF inhibitor | Responsive | ED | Case report |
| KRAS | G12D | Complete Match | EGFR mAb inhibitor | Resistant | ST | Pre-clinical |
| KRAS | G12D | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | L | Early trials |
| KRAS | G12D | Complete Match | Selumetinib (MEK inhibitor) | No Responsive | L | Early trials |
| KRAS | G12D | Complete Match | CDK4/6 inhibitor;MEK inhibitor | Responsive | L | Early trials |
| KRAS | G12D | Complete Match | Trametinib;Ponatinib (MEK inhibitor;BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | LUAD | Pre-clinical |
| KRAS | G12D | Complete Match | Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) | Resistant | COREAD | Late trials |
| KRAS | G12D | Complete Match | pan-RAF inhibitor | Responsive | L | Early trials |
| KRAS | G12D | Complete Match | JAK/TBK1/IKKε inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12D | Complete Match | FAS inhibitor | Responsive | L | Case report |
| KRAS | G12D | Complete Match | HSP90 inhibitor | Responsive | L | Pre-clinical |
| KRAS | G12D | Complete Match | ERK inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12D | Complete Match | PI3K pathway inhibitor;MEK inhibitor | No Responsive | PA | Early trials |
| KRAS | G12D | Complete Match | MEK inhibitor;BCL-XL inhibitor | Responsive | COREAD | Pre-clinical |
| KRAS | G12D | Complete Match | Gemcitabine;MEK inhibitor (Chemotherapy;MEK inhibitor) | Responsive | PA | Early trials |
| KRAS | G12D | Complete Match | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | NCCN guidelines |
| KRAS | G12D | Complete Match | PI3K pathway inhibitor | Resistant | ED | Pre-clinical |
| KRAS | G12D | Complete Match | CDK4/6 inhibitor;MEK inhibitor | Responsive | CESC | Pre-clinical |
| KRAS | G12D | Different Alteration | BRAF inhibitor;MEK inhibitor | Resistant | COREAD | Case report |
| KRAS | G12D | Different Alteration | BRAF inhibitor;EGFR mAb inhibitor | Resistant | COREAD | Case report |
| SMARCA1 | splice_acceptor_variant | Complete Match | EZH2 inhibitor | Responsive | CANCER | Pre-clinical |
| BRAF | R347L | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | CM, LUAD, PRAD | Pre-clinical |
| BRAF | R347L | Different Alteration | MEK inhibitor | Responsive | LUAD, CM, PRAD | Pre-clinical |
| BRAF | R347L | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | OV | Case report |
| BRAF | R347L | Different Alteration | BRAF inhibitor;MEK inhibitor | Responsive | LUAD | Case report |
| ALK | G843R | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | G843R | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | G843R | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | G843R | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | G843R | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | G843R | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | G843R | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | G843R | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | G843R | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | G843R | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | G843R | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | G843R | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | G843R | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | G843R | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | G843R | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | G843R | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | G843R | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | G843R | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | G843R | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| MAP2K1 | E203K | Different Mutation | MEK inhibitor | Resistant | CANCER | Pre-clinical |
| MAP2K1 | E203K | Different Mutation | novel MEK inhibitor | Responsive | CM | Pre-clinical |
| MAP2K1 | E203K | Different Mutation | MEK inhibitor | Resistant | CM | Case report |
| MAP2K1 | E203K | Different Mutation | ERK inhibitor | Responsive | CANCER | Pre-clinical |
| MAP2K1 | E203K | Complete Match | Vemurafenib (BRAF inhibitor) | Resistant | CM | Case report |
| MAP2K1 | E203K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| MAP2K1 | E203K | Different Mutation | Trametinib (MEK inhibitor) | Responsive | CANCER | Pre-clinical |
| MAP2K1 | E203K | Different Mutation | Panitumumab;Trametinib (EGFR mAb inhibitor;MEK inhibitor) | Responsive | COREAD | Case report |
| MAP2K1 | E203K | Different Mutation | Selumetinib (MEK inhibitor) | Responsive | OV | Case report |
| MAP2K1 | E203K | Different Mutation | BRAF inhibitor | Resistant | CM | Early trials |
| MAP2K1 | E203K | Different Mutation | ERK inhibitor | Responsive | CM | Pre-clinical |
| MAP2K1 | E203K | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Case report |
| PTPRD | E661* | Complete Match | IGF1R inhibitor | Responsive | S | Case report |
| AKT3 | S474F | Different Alteration | ATP competitive AKT inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | R582W | Different Alteration | IGF1R inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | R582W | Different Alteration | PI3K pathway inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | R582W | Different Alteration | Midostaurin (Pan-TK inhibitor) | Responsive | BRCA | Pre-clinical |
| FGFR2 | E471D), FGFR2 MUT* (D472Y | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | E471D), FGFR2 MUT* (D472Y | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| TP53 | Q136E | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Q136E | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Q136E | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Q136E | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Q136E | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Q136E | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Q136E | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q136E | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q136E | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Q136E | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Q136E | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Q136E | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q136E | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Q136E | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q136E | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C176* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C176* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C176* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C176* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C176* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C176* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C176* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C176* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C176* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C176* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C176* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C176* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C176* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C176* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C176* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ERBB4 | G500E | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| BRAF | L537S | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | CM, LUAD, PRAD | Pre-clinical |
| BRAF | L537S | Different Alteration | MEK inhibitor | Responsive | LUAD, CM, PRAD | Pre-clinical |
| BRAF | L537S | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | OV | Case report |
| BRAF | L537S | Different Alteration | BRAF inhibitor;MEK inhibitor | Responsive | LUAD | Case report |
| MTOR | I1973F | Different Mutation | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Pre-clinical |
| MTOR | I1973F | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | R | Case report |
| MTOR | I1973F | Complete Match | Everolimus (MTOR inhibitor) | Responsive | AS, R, ST, AG | Case report |
| MTOR | I1973F | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | BLCA | Case report |
| MTOR | I1973F | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | ST | Case report |
| MTOR | I1973F | Different Mutation | Everolimus (MTOR inhibitor) | Resistant | THCA | Case report |
| MTOR | I1973F | Different Mutation | MTOR kinase inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | L130V | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | L130V | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | L130V | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | L130V | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | L130V | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | L130V | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | L130V | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L130V | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L130V | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | L130V | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | L130V | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | L130V | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L130V | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | L130V | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L130V | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ABL1 | I347I | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| ABL1 | I347I | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | I347I | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| ABL1 | I347I | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | I347I | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| ABL1 | I347I | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| TP53 | E286K | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | E286K | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | E286K | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | E286K | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | E286K | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | E286K | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E286K | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E286K | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E286K | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | E286K | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | E286K | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | E286K | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E286K | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | E286K | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E286K | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| FGFR2 | V633I | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | V633I | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| ATR | E1922* | Complete Match | Temozolomide (Chemotherapy) | Responsive | G | Pre-clinical |
| ATR | E1922* | Complete Match | Olaparib (PARP inhibitor) | Responsive | CANCER, OV | Pre-clinical |
| ATR | E1922* | Different Alteration | Olaparib (PARP inhibitor) | Responsive | OV, CANCER | Pre-clinical |
| TP53 | I255F | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | I255F | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | I255F | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | I255F | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | I255F | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | I255F | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | I255F | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | I255F | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | I255F | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | I255F | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | I255F | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | I255F | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | I255F | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | I255F | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | I255F | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | W91* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | W91* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | W91* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | W91* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | W91* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | W91* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | W91* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | W91* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | W91* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | W91* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | W91* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | W91* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | W91* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | W91* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | W91* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ABL1 | D71N | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| ABL1 | D71N | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | D71N | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| ABL1 | D71N | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | D71N | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| ABL1 | D71N | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| PIK3CA | G106R | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | G106R | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | G106R | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | G106R | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | G106R | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | G106R | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | G106R | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | G106R | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | G106R | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | G106R | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | G106R | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | G106R | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | G106R | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | G106R | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| PDGFRA | S1042S | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | MDPS, MDS, ECL, HES | FDA guidelines |
| TP53 | K132T | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | K132T | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | K132T | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | K132T | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | K132T | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | K132T | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | K132T | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | K132T | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | K132T | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | K132T | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | K132T | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | K132T | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | K132T | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | K132T | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | K132T | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| BAP1 | T93A | Complete Match | EZH2 inhibitor | Responsive | MESO | Pre-clinical |
| BAP1 | T93A | Complete Match | PARP inhibitor | Responsive | R, CANCER | Pre-clinical |
| BAP1 | T93A | Complete Match | HDAC inhibitor | Responsive | CM | Pre-clinical |
| BAP1 | T93A | Different Alteration | PARP inhibitor | Responsive | CANCER, R | Pre-clinical |
| BAP1 | T93A | Different Alteration | EZH2 inhibitor | Responsive | MESO | Pre-clinical |
| BAP1 | T93A | Different Alteration | HDAC inhibitor | Responsive | CM | Pre-clinical |
| KMT2A | K255E | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | K255E | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | K255E | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | K255E | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | K255E | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | K255E | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| TP53 | V157G | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | V157G | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | V157G | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | V157G | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | V157G | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | V157G | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | V157G | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V157G | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V157G | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | V157G | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | V157G | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | V157G | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V157G | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | V157G | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V157G | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| BRCA1 | Q139* | Complete Match | Chemotherapy (PARP inhibitor;Chemotherapy) | Responsive | OV | Early trials |
| BRCA1 | Q139* | Complete Match | PARP inhibitor | Responsive | BRCA | Early trials |
| BRCA1 | Q139* | Complete Match | PARP inhibitor;Chemotherapy | Responsive | OV | Early trials |
| BRCA1 | Q139* | Complete Match | Rucaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | Q139* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | Q139* | Complete Match | WEE1 inhibitor | Responsive | CANCER | Case report |
| BRCA1 | Q139* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | OV | Late trials |
| BRCA1 | Q139* | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| BRCA1 | Q139* | Complete Match | Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | Q139* | Complete Match | PARP inhibitor | Responsive | PA | Case report |
| BRCA1 | Q139* | Complete Match | Olaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | Q139* | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| FBXW7 | R465C | Complete Match | Steroid | Responsive | ALL | Late trials |
| FBXW7 | R465C | Complete Match | Tubulin inhibitor | Resistant | CANCER | Pre-clinical |
| FBXW7 | R465C | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | COREAD | Pre-clinical |
| FBXW7 | R465C | Different Alteration | Tubulin inhibitor | Resistant | CANCER | Pre-clinical |
| KMT2A | R442Q | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | R442Q | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | R442Q | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | R442Q | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | R442Q | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | R442Q | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| GATA3 | W329* | Complete Match | Aromatase ihibitor | Responsive | BRCA | Pre-clinical |
| RB1 | R455* | Different Alteration | Palbociclib (CDK4/6 inhibitor) | Responsive | PRAD | Pre-clinical |
| RB1 | R455* | Complete Match | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | R455* | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | R455* | Complete Match | HDAC inhibitor | Responsive | RB | Pre-clinical |
| RB1 | R455* | Different Alteration | MDM2/MDMX inhibitor | Responsive | RB | Pre-clinical |
| RB1 | R455* | Different Alteration | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| RB1 | R455* | Different Alteration | HDAC inhibitor | Responsive | RB | Pre-clinical |
| AKT3 | E84K | Different Alteration | ATP competitive AKT inhibitor | Responsive | BRCA | Pre-clinical |
| TP53 | W91*), TP53 MUT (Y220S | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | W91*), TP53 MUT (Y220S | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | W91*), TP53 MUT (Y220S | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | W91*), TP53 MUT (Y220S | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | W91*), TP53 MUT (Y220S | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | W91*), TP53 MUT (Y220S | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | W91*), TP53 MUT (Y220S | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | W91*), TP53 MUT (Y220S | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | W91*), TP53 MUT (Y220S | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | W91*), TP53 MUT (Y220S | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | W91*), TP53 MUT (Y220S | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | W91*), TP53 MUT (Y220S | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | W91*), TP53 MUT (Y220S | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | W91*), TP53 MUT (Y220S | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | W91*), TP53 MUT (Y220S | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| KMT2A | E1464* | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | E1464* | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | E1464* | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | E1464* | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | E1464* | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | E1464* | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| PDGFB | R216C | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | DFS | FDA guidelines |
| PLCG2 | S225* | Different Mutation | Ibrutinib (BTK inhibitor) | Resistant | CLL | Early trials |
| FAT1 | S3029* | Complete Match | BET inhibitor | Responsive | HNSC | Pre-clinical |
| FBXW7 | G391D | Complete Match | Steroid | Responsive | ALL | Late trials |
| FBXW7 | G391D | Complete Match | Tubulin inhibitor | Resistant | CANCER | Pre-clinical |
| FBXW7 | G391D | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | COREAD | Pre-clinical |
| FBXW7 | G391D | Different Alteration | Tubulin inhibitor | Resistant | CANCER | Pre-clinical |
| RET | D547D | Different Alteration | Nintedanib (Pan-TK inhibitor) | Responsive | LUAD | Case report |
| RET | D547D | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Early trials |
| RET | D547D | Different Alteration | RET inhibitor | Responsive | LUAD | Pre-clinical |
| RET | D547D | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | D547D | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | LUAD | Early trials |
| RET | D547D | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | THCA | Pre-clinical |
| RET | D547D | Different Alteration | Vandetanib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | D547D | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | THCA | Pre-clinical |
| RET | D547D | Different Alteration | RET inhibitor | Responsive | TH | Pre-clinical |
| SF3B1 | N626D | Different Mutation | Spliceosome inhibitor | Responsive | CANCER | Pre-clinical |
| JAK2 | P429P | Different Alteration | Ruxolitinib (JAK inhibitor) | Responsive | ALL | Pre-clinical |
| NOTCH1 | G1376S | Different Alteration | Gamma secretase inhibitor | Responsive | ALL | Pre-clinical |
| NOTCH1 | G1376S | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Mutation | Vemurafenib (BRAF inhibitor) | Resistant | CM | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | HNC | Case report |
| NF1 | splice_acceptor_variant | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_acceptor_variant | Complete Match | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | splice_acceptor_variant | Complete Match | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | splice_acceptor_variant | Complete Match | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Everolimus (MTOR inhibitor) | Responsive | NF | Late trials |
| NF1 | splice_acceptor_variant | Complete Match | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | splice_acceptor_variant | Complete Match | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Nilotinib (BCR-ABL inhibitor) | Responsive | MPN, PLEN | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Everolimus (MTOR inhibitor) | Responsive | HNC, SG | Case report |
| NF1 | splice_acceptor_variant | Complete Match | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | splice_acceptor_variant | Complete Match | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | MEK inhibitor | Responsive | LK, G | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_acceptor_variant | Complete Match | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | MTOR inhibitor | Responsive | LK, G, MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) | Responsive | HC | Case report |
| NF1 | splice_acceptor_variant | Complete Match | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | splice_acceptor_variant | Complete Match | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | splice_acceptor_variant | Complete Match | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | splice_acceptor_variant | Complete Match | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | splice_acceptor_variant | Complete Match | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | splice_acceptor_variant | Complete Match | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | splice_acceptor_variant | Complete Match | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | splice_acceptor_variant | Complete Match | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_acceptor_variant | Complete Match | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | splice_acceptor_variant | Complete Match | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | splice_acceptor_variant | Different Alteration | MTOR inhibitor | Responsive | MPN, G, LK | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | splice_acceptor_variant | Different Alteration | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | splice_acceptor_variant | Different Alteration | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | splice_acceptor_variant | Different Alteration | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | splice_acceptor_variant | Different Alteration | MEK inhibitor | Responsive | G, LK | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | splice_acceptor_variant | Different Alteration | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | splice_acceptor_variant | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | splice_acceptor_variant | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_acceptor_variant | Different Alteration | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | SG, HNC | Case report |
| NF1 | splice_acceptor_variant | Different Alteration | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | splice_acceptor_variant | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_acceptor_variant | Different Alteration | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | splice_acceptor_variant | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | splice_acceptor_variant | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | PLEN, MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | splice_acceptor_variant | Different Alteration | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | splice_acceptor_variant | Different Alteration | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | splice_acceptor_variant | Different Alteration | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | splice_acceptor_variant | Different Alteration | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| TP53 | E286Q | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | E286Q | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | E286Q | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | E286Q | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | E286Q | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | E286Q | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E286Q | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E286Q | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E286Q | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | E286Q | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | E286Q | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | E286Q | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E286Q | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | E286Q | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E286Q | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NOTCH1 | E1903D | Different Alteration | Gamma secretase inhibitor | Responsive | ALL | Pre-clinical |
| NOTCH1 | E1903D | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| PIK3CA | P104L | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | P104L | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | P104L | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | P104L | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | P104L | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | P104L | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | P104L | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | P104L | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | P104L | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | P104L | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | P104L | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | P104L | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | P104L | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | P104L | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| FGFR2 | H545Q | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | H545Q | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| ROS1 | V2068V | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | V2068V | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | V2068V | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | V2068V | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | V2068V | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| NOTCH2 | S1110F | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| ARID1A | Q1631* | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q1631* | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | Q1631* | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | Q1631* | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| NOTCH2 | R2400* | Complete Match | Mk-0752 (Gamma secretase inhibitor) | Responsive | ALL, AML, BRCA | Early trials |
| NOTCH2 | R2400* | Complete Match | OMP-59R5 (NOTCH2 inhibitor) | Responsive | SOLID | Early trials |
| NOTCH2 | R2400* | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| CDH1 | K668* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| PIK3CA | E81K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E81K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E81K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E81K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E81K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E81K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E81K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E81K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E81K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E81K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E81K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E81K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E81K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E81K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| BRD4 | M1073I | Different Alteration | BET inhibitor | Responsive | NMC | Case report |
| HIF1A | Q730* | Different Alteration | Sunitinib (Pan-TK inhibitor) | Responsive | R | Pre-clinical |
| TP53 | E258* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | E258* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | E258* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | E258* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | E258* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | E258* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | E258* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E258* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | E258* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | E258* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | E258* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | E258* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E258* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | E258* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | E258* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| MET | D414N | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | G | Case report |
| PDGFRA | 3-UTRSNV | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | MDPS, MDS, ECL, HES | FDA guidelines |
| CDK12 | E488* | Complete Match | PARP inhibitor | Responsive | OV | Pre-clinical |
| CDK12 | E488* | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| NTRK1 | L96V | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Case report |
| NTRK1 | L96V | Different Alteration | Pan-TKR inhibitor | Responsive | CANCER | Early trials |
| NTRK1 | L96V | Different Alteration | Pan-TK inhibitor | Responsive | LUAD | Pre-clinical |
| NTRK1 | L96V | Different Alteration | Pan-TK inhibitor | Responsive | COREAD | Case report |
| ARID1A | R1335* | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | R1335* | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | R1335* | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | R1335* | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Q192* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Q192* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Q192* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Q192* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Q192* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Q192* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Q192* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q192* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q192* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Q192* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Q192* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Q192* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q192* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Q192* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q192* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ALK | V597G | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | V597G | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | V597G | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | V597G | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | V597G | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | V597G | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | V597G | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | V597G | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | V597G | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | V597G | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | V597G | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | V597G | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | V597G | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | V597G | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | V597G | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | V597G | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | V597G | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | V597G | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | V597G | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| PIK3CA | E542K), PIK3CA MUT (E726K | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E542K), PIK3CA MUT (E726K | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E542K), PIK3CA MUT (E726K | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| NF1 | S2601* | Different Mutation | Vemurafenib (BRAF inhibitor) | Resistant | CM | Pre-clinical |
| NF1 | S2601* | Different Mutation | Everolimus (MTOR inhibitor) | Responsive | HNC | Case report |
| NF1 | S2601* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | S2601* | Complete Match | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | S2601* | Complete Match | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Complete Match | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Complete Match | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | S2601* | Complete Match | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | S2601* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | NF | Late trials |
| NF1 | S2601* | Complete Match | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | S2601* | Complete Match | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Complete Match | Nilotinib (BCR-ABL inhibitor) | Responsive | MPN, PLEN | Pre-clinical |
| NF1 | S2601* | Complete Match | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | HNC, SG | Case report |
| NF1 | S2601* | Complete Match | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | S2601* | Complete Match | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | S2601* | Complete Match | MEK inhibitor | Responsive | LK, G | Pre-clinical |
| NF1 | S2601* | Complete Match | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | S2601* | Complete Match | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | S2601* | Complete Match | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Complete Match | MTOR inhibitor | Responsive | LK, G, MPN | Pre-clinical |
| NF1 | S2601* | Complete Match | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | S2601* | Complete Match | Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) | Responsive | HC | Case report |
| NF1 | S2601* | Complete Match | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | S2601* | Complete Match | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | S2601* | Complete Match | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | S2601* | Complete Match | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | S2601* | Complete Match | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | S2601* | Complete Match | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | S2601* | Complete Match | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | S2601* | Complete Match | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | S2601* | Complete Match | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Complete Match | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | S2601* | Complete Match | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | S2601* | Complete Match | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | S2601* | Different Alteration | MTOR inhibitor | Responsive | MPN, G, LK | Pre-clinical |
| NF1 | S2601* | Different Alteration | PLX3397 (Pan-TK inhibitor) | Responsive | PLEN | Pre-clinical |
| NF1 | S2601* | Different Alteration | Erlotinib (EGFR inhibitor) | Resistant | L | Pre-clinical |
| NF1 | S2601* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | G | Case report |
| NF1 | S2601* | Different Alteration | BRD4 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Different Alteration | Trametinib (MEK inhibitor) | No Responsive | OS | Case report |
| NF1 | S2601* | Different Alteration | Cediranib (ALK inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | S2601* | Different Alteration | Bevacizumab (VEGFR mAb inhibitor) | Responsive | G | Case report |
| NF1 | S2601* | Different Alteration | MEK inhibitor | Responsive | G, LK | Pre-clinical |
| NF1 | S2601* | Different Alteration | Vinblastine (Chemotherapy) | Responsive | G | Early trials |
| NF1 | S2601* | Different Alteration | Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Different Alteration | Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) | No Responsive | MPN | Early trials |
| NF1 | S2601* | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Resistant | L | Pre-clinical |
| NF1 | S2601* | Different Alteration | MTOR inhibitor;HSP90 inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Different Alteration | Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | Responsive | G | Case report |
| NF1 | S2601* | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | PLEN | Early trials |
| NF1 | S2601* | Different Alteration | Tamoxifen (Hormonal therapy) | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | SG, HNC | Case report |
| NF1 | S2601* | Different Alteration | Pan-RAF inhibitor;MEK inhibitor | Responsive | CM | Pre-clinical |
| NF1 | S2601* | Different Alteration | Tipifarnib (Farnesyltransferase inhibitor) | No Responsive | PLEN | Early trials |
| NF1 | S2601* | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | PLEN | Early trials |
| NF1 | S2601* | Different Alteration | Retinoic Acid | Resistant | NB | Pre-clinical |
| NF1 | S2601* | Different Alteration | Everolimus (MTOR inhibitor) | No Responsive | MPN | Early trials |
| NF1 | S2601* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | PLEN | Early trials |
| NF1 | S2601* | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | PLEN, MPN | Pre-clinical |
| NF1 | S2601* | Different Alteration | Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) | Responsive | G | Case report |
| NF1 | S2601* | Different Alteration | Trametinib (MEK inhibitor) | Responsive | CM | Pre-clinical |
| NF1 | S2601* | Different Alteration | AURK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Different Alteration | Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) | No Responsive | G | Case report |
| NF1 | S2601* | Different Alteration | PD1 Ab inhibitor | Responsive | CM | Early trials |
| NF1 | S2601* | Different Alteration | MEK inhibitor | Responsive | MPN | Pre-clinical |
| NF1 | S2601* | Different Alteration | KIT inhibitor;MTOR inhibitor | Responsive | MPN | Pre-clinical |
| TP53 | L257R | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | L257R | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | L257R | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | L257R | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | L257R | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | L257R | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | L257R | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L257R | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | L257R | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | L257R | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | L257R | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | L257R | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L257R | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | L257R | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | L257R | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NRG1 | A547T | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Pre-clinical |
| NRG1 | A547T | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Case report |
| TP53 | D281E | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | D281E | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | D281E | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | D281E | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | D281E | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | D281E | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | D281E | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | D281E | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | D281E | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | D281E | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | D281E | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | D281E | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | D281E | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | D281E | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | D281E | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | F258L), PTEN MUT (F258Y | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | F258L), PTEN MUT (F258Y | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | F258L), PTEN MUT (F258Y | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | F258L), PTEN MUT (F258Y | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | F258L), PTEN MUT (F258Y | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | F258L), PTEN MUT (F258Y | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | F258L), PTEN MUT (F258Y | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | F258L), PTEN MUT (F258Y | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | F258L), PTEN MUT (F258Y | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | F258L), PTEN MUT (F258Y | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | F258L), PTEN MUT (F258Y | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| RAF1 | E607Q | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | PRAD | Pre-clinical |
| RAF1 | E607Q | Different Alteration | Pan-RAF inhibitor | Responsive | PRAD | Pre-clinical |
| RAF1 | E607Q | Different Alteration | U0126 (MEK inhibitor) | Responsive | PRAD | Pre-clinical |
| BRD4 | intron_variant | Different Alteration | BET inhibitor | Responsive | NMC | Case report |
| TP53 | R280K | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | R280K | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | R280K | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | R280K | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | R280K | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | R280K | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | R280K | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R280K | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | R280K | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | R280K | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | R280K | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | R280K | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R280K | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | R280K | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | R280K | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| SF3B1 | K666N | Complete Match | Spliceosome inhibitor | Responsive | CANCER | Pre-clinical |
| PIK3CA | E545K), PIK3CA MUT (C420R | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | E545K), PIK3CA MUT (C420R | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | E545K), PIK3CA MUT (C420R | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| NTRK3 | L827F | Different Alteration | IGF1R inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | L827F | Different Alteration | PI3K pathway inhibitor | Responsive | BRCA | Pre-clinical |
| NTRK3 | L827F | Different Alteration | Midostaurin (Pan-TK inhibitor) | Responsive | BRCA | Pre-clinical |
| SMARCA4 | splice_acceptor_variant | Complete Match | EZH2 inhibitor | Responsive | OVRT | Case report |
| SMARCA4 | splice_acceptor_variant | Complete Match | AURKA inhibitor | Responsive | NSCLC | Pre-clinical |
| SMARCA4 | splice_acceptor_variant | Complete Match | EZH2 inhibitor | Responsive | OV | Case report |
| SMARCA4 | splice_acceptor_variant | Different Alteration | EZH2 inhibitor | Responsive | OVRT | Case report |
| SMARCA4 | splice_acceptor_variant | Different Alteration | EZH2 inhibitor | Responsive | OV | Case report |
| ERBB4 | 5-UTRSNV | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| BCR | D904N | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| BCR | D904N | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| BCR | D904N | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | D904N | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | D904N | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| BCR | D904N | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| PTEN | L140* | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | L140* | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | L140* | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | L140* | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | L140* | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | L140* | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | L140* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | L140* | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | L140* | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | L140* | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | L140* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | L140* | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | L140* | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | L140* | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | L140* | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | L140* | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | L140* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | L140* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | L140* | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | L140* | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | L140* | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | L140* | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | L140* | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | L140* | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | L140* | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| CDK12 | Y246* | Complete Match | PARP inhibitor | Responsive | OV | Pre-clinical |
| CDK12 | Y246* | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| TP53 | T253S), TP53 MUT (Q331* | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | T253S), TP53 MUT (Q331* | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | T253S), TP53 MUT (Q331* | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | T253S), TP53 MUT (Q331* | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | T253S), TP53 MUT (Q331* | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | T253S), TP53 MUT (Q331* | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | T253S), TP53 MUT (Q331* | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | T253S), TP53 MUT (Q331* | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | T253S), TP53 MUT (Q331* | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | T253S), TP53 MUT (Q331* | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | T253S), TP53 MUT (Q331* | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | T253S), TP53 MUT (Q331* | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | T253S), TP53 MUT (Q331* | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | T253S), TP53 MUT (Q331* | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | T253S), TP53 MUT (Q331* | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| BCR | I57I | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| BCR | I57I | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| BCR | I57I | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | I57I | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | I57I | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| BCR | I57I | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| PTEN | D92E | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | D92E | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | D92E | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | D92E | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | D92E | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | D92E | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | D92E | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | D92E | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | D92E | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | D92E | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | D92E | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | D92E | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | D92E | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | D92E | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | D92E | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | D92E | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | D92E | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | D92E | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | D92E | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | D92E | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | D92E | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | D92E | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | D92E | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | D92E | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | D92E | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PIK3CA | N345H | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | N345H | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | N345H | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | N345H | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | N345H | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | N345H | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | N345H | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | N345H | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | N345H | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | N345H | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | N345H | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | N345H | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | N345H | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | N345H | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| FGFR3 | 3-UTRSNV | Different Alteration | FGFR inhibitor | Responsive | BLCA | Case report |
| FGFR3 | 3-UTRSNV | Different Alteration | FGFR inhibitor | Responsive | G | Early trials |
| FGFR3 | 3-UTRSNV | Different Alteration | FGFR inhibitor | Responsive | NSCLC | Pre-clinical |
| PTEN | A126G | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | A126G | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | A126G | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | A126G | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | A126G | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | A126G | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | A126G | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | A126G | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | A126G | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | A126G | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | A126G | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | A126G | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | A126G | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | A126G | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | A126G | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | A126G | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | A126G | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | A126G | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | A126G | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | A126G | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | A126G | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | A126G | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | A126G | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | A126G | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | A126G | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| EGFR | intron_variant | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | intron_variant | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| EGFR | E928V | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | E928V | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| TP53 | V157D | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | V157D | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | V157D | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | V157D | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | V157D | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | V157D | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | V157D | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V157D | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | V157D | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | V157D | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | V157D | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | V157D | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V157D | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | V157D | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | V157D | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| RAF1 | R354W | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | PRAD | Pre-clinical |
| RAF1 | R354W | Different Alteration | Pan-RAF inhibitor | Responsive | PRAD | Pre-clinical |
| RAF1 | R354W | Different Alteration | U0126 (MEK inhibitor) | Responsive | PRAD | Pre-clinical |
| NOTCH2 | C1342C | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| GATA3 | K347* | Complete Match | Aromatase ihibitor | Responsive | BRCA | Pre-clinical |
| PIK3CA | P366R | Different Mutation | BRAF inhibitor | Resistant | CM | Case report |
| PIK3CA | P366R | Complete Match | PI3K pathway inhibitor | Responsive | BLCA, HNC | Case report |
| PIK3CA | P366R | Complete Match | PI3K pathway inhibitor | Responsive | HNSC | Case report |
| PIK3CA | P366R | Complete Match | PI3K pathway inhibitor | Responsive | G, THCA | Pre-clinical |
| PIK3CA | P366R | Complete Match | Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) | Responsive | BRCA | Late trials |
| PIK3CA | P366R | Complete Match | PI3K pathway inhibitor | Responsive | COREAD | Pre-clinical |
| PIK3CA | P366R | Complete Match | PI3K pathway inhibitor | Responsive | ED, OV, CESC | Early trials |
| PIK3CA | P366R | Complete Match | PI3K pathway inhibitor | Responsive | BRCA | Late trials |
| PIK3CA | P366R | Complete Match | PIK3CA inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | P366R | Complete Match | PIK3CA inhibitor | Responsive | ST | Case report |
| PIK3CA | P366R | Complete Match | AKT inhibitor | Responsive | BRCA | Early trials |
| PIK3CA | P366R | Complete Match | PI3K pathway inhibitor | Responsive;Responsive | L | Pre-clinical;Case report |
| PIK3CA | P366R | Complete Match | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Late trials |
| PIK3CA | P366R | Different Alteration | PI3K pathway inhibitor | Resistant | BRCA | Pre-clinical |
| EGFR | A289V | Different Alteration | Cetuximab (EGFR mAb inhibitor) | Responsive | COREAD | FDA guidelines |
| EGFR | A289V | Different Alteration | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | FDA guidelines |
| EGFR | A289V | Different Mutation | Rindopepimut (Vaccine) | Responsive | GB | Late trials |
| EGFR | A289V | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | A289V | Different Mutation | Gefitinib (EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | A289V | Different Mutation | HSP90 inhibitor | Responsive | L | Early trials |
| EGFR | A289V | Different Mutation | Afatinib;Cetuximab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) | Responsive | L | Early trials |
| EGFR | A289V | Different Mutation | MEK inhibitor | Responsive | L | Pre-clinical |
| EGFR | A289V | Different Mutation | EGFR TK inhibitor | Responsive | L | Late trials |
| EGFR | A289V | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | NCCN guidelines |
| EGFR | A289V | Different Mutation | Osimertinib (EGFR inhibitor) | Resistant | L | Early trials |
| EGFR | A289V | Different Mutation | EGFR-TKI's (EGFR inhibitor) | Resistant | L | Late trials |
| EGFR | A289V | Different Mutation | HSP90 inhibitor | Responsive | L | Case report |
| EGFR | A289V | Different Mutation | EGFR inhibitor | Resistant | L | Late trials |
| EGFR | A289V | Different Mutation | Poziotinib (EGFR inhibitor) | Responsive | L | Early trials |
| EGFR | A289V | Different Mutation | Osimertinib (EGFR inhibitor) | Responsive | L | Pre-clinical |
| EGFR | A289V | Different Mutation | HSP90 inhibitor (HSP90 inhibitor) | Responsive | L | Early trials |
| EGFR | A289V | Complete Match | Erlotinib (EGFR inhibitor) | Responsive | G | Pre-clinical |
| EGFR | A289V | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | A289V | Different Mutation | Osimertinib (EGFR inhibitor) | Responsive | L | Early trials |
| EGFR | A289V | Different Mutation | Rociletinib (EGFR inhibitor) | Resistant | LUAD | Case report |
| EGFR | A289V | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Responsive | COREAD | Case report |
| EGFR | A289V | Different Mutation | novel EGFR mAb inhibitor | Responsive | COREAD | Early trials |
| EGFR | A289V | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| EGFR | A289V | Different Mutation | Cetuximab;Sirolimus (EGFR mAb inhibitor;MTOR inhibitor) | Responsive | HNC | Case report |
| EGFR | A289V | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | A289V | Different Mutation | Gefitinib (EGFR inhibitor) | No Responsive | HNC | Case report |
| EGFR | A289V | Different Mutation | EGFR inhibitor | Responsive | L | Early trials |
| EGFR | A289V | Different Mutation | Erlotinib (EGFR inhibitor) | Resistant | L | NCCN/CAP guidelines |
| EGFR | A289V | Different Mutation | Osimertinib (EGFR inhibitor) | Responsive | NSCLC | FDA guidelines |
| EGFR | A289V | Different Mutation | EGFR inhibitor | Responsive | NSCLC | Late trials |
| EGFR | A289V | Different Mutation | Afatinib;Nimotuzumab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) | Responsive | L | Early trials |
| EGFR | A289V | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Resistant | L | NCCN/CAP guidelines |
| EGFR | A289V | Different Mutation | Erlotinib (EGFR inhibitor) | Responsive | L | Early trials |
| EGFR | A289V | Different Mutation | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | L | Late trials |
| EGFR | A289V | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Pre-clinical |
| EGFR | A289V | Different Mutation | Erlotinib (EGFR inhibitor) | No Responsive | L | Case report |
| EGFR | A289V | Different Mutation | Lapatinib (ERBB2 inhibitor) | Responsive | ED | Case report |
| EGFR | A289V | Different Mutation | EGFR inhibitor | No Responsive | G | Early trials |
| EGFR | A289V | Different Mutation | EGFR inhibitor | Resistant | NSCLC | Case report |
| EGFR | A289V | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| EGFR | A289V | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant;Resistant | COREAD | Pre-clinical;Case report |
| EGFR | A289V | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Responsive | HNC | Case report |
| EGFR | A289V | Different Alteration | Gefitinib (EGFR inhibitor) | Responsive | ED | Late trials |
| EGFR | A289V | Different Alteration | Gefitinib (EGFR inhibitor) | No Responsive | HNC | Early trials |
| EGFR | A289V | Different Alteration | EGFR inhibitor | Responsive | HNSC | Case report |
| EGFR | A289V | Different Alteration | EGFR inhibitor | No Responsive | G | Early trials |
| EGFR | A289V | Different Alteration | Erlotinib (EGFR inhibitor) | No Responsive | L | Early trials |
| EGFR | A289V | Different Alteration | EGFR mAb inhibitor | Responsive | COREAD | Late trials |
| EGFR | A289V | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | A289V | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| CDH1 | R335* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| TP53 | H179Q | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | H179Q | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | H179Q | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | H179Q | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | H179Q | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | H179Q | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | H179Q | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H179Q | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | H179Q | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | H179Q | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | H179Q | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | H179Q | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H179Q | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | H179Q | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | H179Q | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| BRCA1 | Q1408* | Complete Match | Chemotherapy (PARP inhibitor;Chemotherapy) | Responsive | OV | Early trials |
| BRCA1 | Q1408* | Complete Match | PARP inhibitor | Responsive | BRCA | Early trials |
| BRCA1 | Q1408* | Complete Match | PARP inhibitor;Chemotherapy | Responsive | OV | Early trials |
| BRCA1 | Q1408* | Complete Match | Rucaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | Q1408* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | Q1408* | Complete Match | WEE1 inhibitor | Responsive | CANCER | Case report |
| BRCA1 | Q1408* | Complete Match | Platinum Agent (Chemotherapy) | Responsive | OV | Late trials |
| BRCA1 | Q1408* | Complete Match | Olaparib (PARP inhibitor) | Responsive | PRAD | Early trials |
| BRCA1 | Q1408* | Complete Match | Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) | Responsive | BRCA | Early trials |
| BRCA1 | Q1408* | Complete Match | PARP inhibitor | Responsive | PA | Case report |
| BRCA1 | Q1408* | Complete Match | Olaparib (PARP inhibitor) | Responsive | OV | FDA guidelines |
| BRCA1 | Q1408* | Different Alteration | PARP inhibitor | Responsive | OV | Pre-clinical |
| CDH1 | E512* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| HRAS | G12D | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | CER | Pre-clinical |
| HRAS | G12D | Complete Match | MEK inhibitor +/- MTOR inhibitor | Responsive | AML | Pre-clinical |
| HRAS | G12D | Complete Match | MTOR inhibitor | Responsive | CESC | Pre-clinical |
| HRAS | G12D | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | Responsive | CANCER | Early trials |
| ERCC2 | splice_donor_variant | Complete Match | Cisplatin (Chemotherapy) | Responsive | BLCA | Early trials |
| ERCC2 | splice_donor_variant | Complete Match | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| ERCC2 | splice_donor_variant | Different Alteration | PD1/PDL1 inhibitor | Responsive | UTH | Early trials |
| NTRK1 | D209H | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Case report |
| NTRK1 | D209H | Different Alteration | Pan-TKR inhibitor | Responsive | CANCER | Early trials |
| NTRK1 | D209H | Different Alteration | Pan-TK inhibitor | Responsive | LUAD | Pre-clinical |
| NTRK1 | D209H | Different Alteration | Pan-TK inhibitor | Responsive | COREAD | Case report |
| TP53 | C242G | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C242G | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C242G | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C242G | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C242G | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C242G | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C242G | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C242G | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C242G | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C242G | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C242G | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C242G | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C242G | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C242G | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C242G | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| EGFR | E97Q | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | L | Case report |
| EGFR | E97Q | Different Alteration | Erlotinib (EGFR inhibitor) | Responsive | NSCLC | Case report |
| ROS1 | L1872V | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | L1872V | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | L1872V | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | L1872V | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | L1872V | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| TP53 | M169I | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | M169I | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | M169I | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | M169I | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | M169I | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | M169I | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | M169I | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | M169I | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | M169I | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | M169I | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | M169I | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | M169I | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | M169I | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | M169I | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | M169I | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| NOTCH2 | D1306N), NOTCH2 MUT* (3-UTRSNV | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| NRG1 | R18Q | Different Alteration | Lapatinib (ERBB2 inhibitor) | Responsive | LUAD | Pre-clinical |
| NRG1 | R18Q | Different Alteration | Afatinib (ERBB2 & EGFR inhibitor) | Responsive | LUAD | Case report |
| ABL1 | 3-UTRSNV | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| ABL1 | 3-UTRSNV | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | 3-UTRSNV | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| ABL1 | 3-UTRSNV | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| ABL1 | 3-UTRSNV | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| ABL1 | 3-UTRSNV | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| FGFR2 | H254Y | Different Alteration | FGFR inhibitor | Responsive | COREAD | Early trials |
| FGFR2 | H254Y | Different Alteration | FGFR inhibitor | Responsive | BT | Early trials |
| CDKN1B | Q141*), CDKN1B MUT (Q20* | Complete Match | CDK2/4 inhibitor | Responsive | CANCER | Pre-clinical |
| CDKN1B | Q141*), CDKN1B MUT (Q20* | Different Alteration | CDK2/4 inhibitor | Responsive | CANCER | Pre-clinical |
| NOTCH2 | L1690L | Different Alteration | Gamma secretase inhibitor | Responsive | BRCA | Pre-clinical |
| TP53 | S127Y | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | S127Y | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | S127Y | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | S127Y | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | S127Y | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | S127Y | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | S127Y | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | S127Y | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | S127Y | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | S127Y | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | S127Y | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | S127Y | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | S127Y | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | S127Y | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | S127Y | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C275Y | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | C275Y | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | C275Y | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | C275Y | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | C275Y | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | C275Y | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | C275Y | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C275Y | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | C275Y | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | C275Y | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | C275Y | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | C275Y | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C275Y | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | C275Y | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | C275Y | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| PTEN | Q149* | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | Q149* | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | Q149* | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | Q149* | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | Q149* | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | Q149* | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | Q149* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | Q149* | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | Q149* | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | Q149* | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | Q149* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | Q149* | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | Q149* | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | Q149* | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | Q149* | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | Q149* | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | Q149* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | Q149* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | Q149* | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | Q149* | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | Q149* | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | Q149* | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | Q149* | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | Q149* | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | Q149* | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | Y76* | Different Mutation | Cetuximab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | Y76* | Different Mutation | Panitumumab (EGFR mAb inhibitor) | Resistant | COREAD | Case report |
| PTEN | Y76* | Different Mutation | BYL719 (PIK3CA inhibitor) | Resistant | BRCA | Case report |
| PTEN | Y76* | Complete Match | ATM inhibitor | Responsive | BRCA | Pre-clinical |
| PTEN | Y76* | Complete Match | PI3K pathway inhibitor | Responsive | BRCA, ED, TH, CANCER, L, G, OV | Pre-clinical |
| PTEN | Y76* | Complete Match | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | Y76* | Complete Match | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | Y76* | Complete Match | PARP inhibitor | Responsive | ED | Case report |
| PTEN | Y76* | Complete Match | PD1 Ab inhibitor | Resistant | CM | Early trials |
| PTEN | Y76* | Complete Match | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | Y76* | Complete Match | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | Y76* | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| PTEN | Y76* | Complete Match | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | Y76* | Complete Match | AKT inhibitor | Responsive | PA | Case report |
| PTEN | Y76* | Complete Match | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | Y76* | Different Alteration | PI3K pathway inhibitor | Responsive | L, BRCA, CANCER, G, ED, TH, OV | Pre-clinical |
| PTEN | Y76* | Different Alteration | Everolimus (MTOR inhibitor) | Responsive | PRAD | Early trials |
| PTEN | Y76* | Different Alteration | Sirolimus (MTOR inhibitor) | Responsive | CANCER | Early trials |
| PTEN | Y76* | Different Alteration | PARP inhibitor | Responsive | ED | Case report |
| PTEN | Y76* | Different Alteration | PIK3CB inhibitor | Responsive | PRAD | Case report |
| PTEN | Y76* | Different Alteration | EGFR mAb inhibitor | Resistant | COREAD | Late trials |
| PTEN | Y76* | Different Alteration | MTOR inhibitor | No Responsive | ED | Early trials |
| PTEN | Y76* | Different Alteration | AKT inhibitor | Responsive | PA | Case report |
| PTEN | Y76* | Different Alteration | PI3K pathway inhibitor;AR antagonist | Responsive | PRAD | Pre-clinical |
| PTEN | Y76* | Different Alteration | PI3K pathway inhibitor;MEK inhibitor | Responsive | OV | Pre-clinical |
| IDH1 | R132H | Complete Match | Venetoclax (BCL2 inhibitor) | Responsive | AML | Early trials |
| IDH1 | R132H | Complete Match | IDH1 inhibitor | Responsive | AML | Early trials |
| IDH1 | R132H | Complete Match | AG-120 (IDH1 inhibitor) | Responsive | G | Early trials |
| IDH1 | R132H | Complete Match | Dasatinib (BCR-ABL inhibitor) | Responsive | CH | Early trials |
| IDH1 | R132H | Complete Match | Ivosidenib (IDH1 inhibitor) | Responsive | AML | Early trials |
| IDH1 | R132H | Complete Match | BCL2 inhibitor | Responsive | AML | Pre-clinical |
| IDH1 | R132H | Complete Match | BCL2 inhibitor (BCL2 inhibitor) | Responsive | AML | Pre-clinical |
| IDH1 | R132H | Complete Match | Dasatinib (BCR-ABL inhibitor) | Responsive | BT | Pre-clinical |
| IDH1 | R132H | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| BRAF | A569D | Different Alteration | Sorafenib (Pan-TK inhibitor) | Responsive | CM, LUAD, PRAD | Pre-clinical |
| BRAF | A569D | Different Alteration | MEK inhibitor | Responsive | LUAD, CM, PRAD | Pre-clinical |
| BRAF | A569D | Different Alteration | Selumetinib (MEK inhibitor) | Responsive | OV | Case report |
| BRAF | A569D | Different Alteration | BRAF inhibitor;MEK inhibitor | Responsive | LUAD | Case report |
| HRAS | G12C | Complete Match | PI3K pathway inhibitor;MEK inhibitor | Responsive | CER | Pre-clinical |
| HRAS | G12C | Complete Match | MEK inhibitor +/- MTOR inhibitor | Responsive | AML | Pre-clinical |
| HRAS | G12C | Complete Match | MTOR inhibitor | Responsive | CESC | Pre-clinical |
| HRAS | G12C | Complete Match | Tipifarnib (Farnesyltransferase inhibitor) | Responsive | CANCER | Early trials |
| CDH1 | Q673* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| KMT2A | I1401F | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | I1401F | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | I1401F | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | I1401F | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | I1401F | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | I1401F | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| BAP1 | Y627* | Complete Match | EZH2 inhibitor | Responsive | MESO | Pre-clinical |
| BAP1 | Y627* | Complete Match | PARP inhibitor | Responsive | R, CANCER | Pre-clinical |
| BAP1 | Y627* | Complete Match | HDAC inhibitor | Responsive | CM | Pre-clinical |
| BAP1 | Y627* | Different Alteration | PARP inhibitor | Responsive | CANCER, R | Pre-clinical |
| BAP1 | Y627* | Different Alteration | EZH2 inhibitor | Responsive | MESO | Pre-clinical |
| BAP1 | Y627* | Different Alteration | HDAC inhibitor | Responsive | CM | Pre-clinical |
| BCR | 3-UTRSNV | Different Alteration | Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) | Responsive | CML, ALL | FDA guidelines |
| BCR | 3-UTRSNV | Different Alteration | Imatinib (BCR-ABL inhibitor & KIT inhibitor) | Responsive | ALL, CML | FDA guidelines |
| BCR | 3-UTRSNV | Different Alteration | Nilotinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | 3-UTRSNV | Different Alteration | Bosutinib (BCR-ABL inhibitor) | Responsive | CML | FDA guidelines |
| BCR | 3-UTRSNV | Different Alteration | Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) | Responsive | ALL | Pre-clinical |
| BCR | 3-UTRSNV | Different Alteration | Dasatinib (BCR-ABL inhibitor) | Responsive | ALL, CML | FDA guidelines |
| KMT2A | 3-UTRSNV | Different Alteration | EPZ-5676 (DOT1L inhibitor) | Responsive | ALL, MDS, AML | Early trials |
| KMT2A | 3-UTRSNV | Different Alteration | BET inhibitor | Responsive | ALL | Pre-clinical |
| KMT2A | 3-UTRSNV | Different Alteration | BET inhibitor | Responsive | AML | Pre-clinical |
| KMT2A | 3-UTRSNV | Different Alteration | Daunorubicin (Chemotherapy) | Responsive | AML | FDA guidelines |
| KMT2A | 3-UTRSNV | Different Alteration | Belinostat (HDAC inhibitor) | Responsive | AML | Early trials |
| KMT2A | 3-UTRSNV | Different Alteration | DOT1L inhibitor | Responsive | AML | Early trials |
| TP53 | Q136P | Different Mutation | HSP90 inhibitor | Responsive | CANCER | Pre-clinical |
| TP53 | Q136P | Complete Match | Decitabine (Chemotherapy) | Responsive | AML, MDPS | Early trials |
| TP53 | Q136P | Complete Match | Abemaciclib (CDK4/6 inhibitor) | Resistant | BRCA | Early trials |
| TP53 | Q136P | Different Mutation | HDM2 inhibitor | Responsive | AML | Early trials |
| TP53 | Q136P | Complete Match | Cisplatin (Chemotherapy) | Resistant | FGCT, MGCT | Early trials |
| TP53 | Q136P | Complete Match | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| TP53 | Q136P | Complete Match | Gemcitabine (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q136P | Complete Match | Mitomycin C (Chemotherapy) | Responsive | BLCA | Pre-clinical |
| TP53 | Q136P | Complete Match | WEE1 inhibitor | Responsive | HNC | Pre-clinical |
| TP53 | Q136P | Complete Match | MDM2 inhibitor | Resistant | LIP | Early trials |
| TP53 | Q136P | Complete Match | Doxorubicin (Anthracycline antitumor antibiotic) | Responsive | BLCA | Pre-clinical |
| TP53 | Q136P | Complete Match | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q136P | Complete Match | WEE1 inhibitor | Responsive | OV | Early trials |
| TP53 | Q136P | Different Alteration | Pramlintide (Amylin analogue) | Responsive | THYM | Pre-clinical |
| TP53 | Q136P | Different Alteration | AZD6738 (ATR inhibitor) | Responsive | BCL | Early trials |
| ALK | E296K | Different Alteration | ALK inhibitor;SRC inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | E296K | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | GB, LY | Early trials |
| ALK | E296K | Different Alteration | Lorlatinib (ALK&ROS1 inhibitor) | Responsive | NSCLC | Early trials |
| ALK | E296K | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | THCA, IM | Case report |
| ALK | E296K | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Early trials |
| ALK | E296K | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | E296K | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | IM, COREAD | Case report |
| ALK | E296K | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD, NSCLC | FDA guidelines |
| ALK | E296K | Different Alteration | Brigatinib (Pan-TK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | E296K | Different Alteration | Entrictinib (Pan-TK inhibitor) | Responsive | COREAD | Case report |
| ALK | E296K | Different Alteration | Alectinib (ALK inhibitor) | Responsive | LUAD | FDA guidelines |
| ALK | E296K | Different Alteration | HSP90 inhibitor (HSP90 inhibitor) | Responsive | LUAD | Early trials |
| ALK | E296K | Different Alteration | ALK inhibitor;IGF1R inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | E296K | Different Alteration | ALK inhibitor;MEK inhibitor | Responsive | LUAD | Pre-clinical |
| ALK | E296K | Different Alteration | novel ALK inhibitor | Responsive | LUAD | Early trials |
| ALK | E296K | Different Alteration | Ceritinib (ALK inhibitor) | Responsive | HEMATO | Early trials |
| ALK | E296K | Different Alteration | ALK inhibitor | Responsive | COREAD | Case report |
| ALK | E296K | Different Alteration | Alectinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ALK | E296K | Different Alteration | MEK inhibitor (ALK inhibitor;MEK inhibitor) | Responsive | LUAD | Pre-clinical |
| ROS1 | splice_acceptor_variant | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | IM | Case report |
| ROS1 | splice_acceptor_variant | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | NSCLC | FDA guidelines |
| ROS1 | splice_acceptor_variant | Different Alteration | Cabozantinib (Pan-kinase inhibitor) | Responsive | LUAD | Case report |
| ROS1 | splice_acceptor_variant | Different Alteration | HSP90 inhibitor | Responsive | LUAD | Pre-clinical |
| ROS1 | splice_acceptor_variant | Different Alteration | Crizotinib (ALK inhibitor) | Responsive | LUAD | Early trials |
| ERBB4 | H190Y | Different Alteration | Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) | Responsive | LUAD | Pre-clinical |
| SMARCA1 | S324* | Complete Match | EZH2 inhibitor | Responsive | CANCER | Pre-clinical |
| CDH1 | Q129* | Complete Match | Bicalutamide (AR inhibitor) | Responsive | BRCA | Pre-clinical |
| ARID1A | splice_acceptor_variant | Complete Match | EZH2 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | splice_acceptor_variant | Complete Match | PD1 inhibitor | Responsive | OV | Pre-clinical |
| ARID1A | splice_acceptor_variant | Complete Match | PARP inhibitor | Responsive | CANCER | Pre-clinical |
| ARID1A | splice_acceptor_variant | Complete Match | ATR inhibitor | Responsive | CANCER | Pre-clinical |
| Variation | Gene | Transcript | Protein Alteration | Consequence | Tumour Driver | Oncogenic Classification |
|---|
Drug-Gene Interactions help
Druggable categories in the cohort
Focus the search to a gene of interest:
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| Gene | Interaction Source | Interaction Types | Drug Claim Primary Name | Drug Name | ChEMBL ID |
|---|---|---|---|---|---|
| TP53 | CKB | CTX-1 | |||
| TP53 | CKB | Gemcitabine | GEMCITABINE | CHEMBL888 | |
| TP53 | ClearityFoundationClinicalTrial | GRANISETRON | GRANISETRON | CHEMBL289469 | |
| TP53 | CKB | epirubicin | EPIRUBICIN | CHEMBL417 | |
| TP53 | NCI | TOPICAL CORTICOSTEROIDS | |||
| TP53 | CKB | Trametinib | TRAMETINIB | CHEMBL2103875 | |
| TP53 | TALC | vaccine | AD.P53-DC | ||
| TP53 | CKB | Cisplatin | |||
| TP53 | NCI | YONDELIS | YONDELIS | CHEMBL297812 | |
| TP53 | CKB | Doxorubicin | DOXORUBICIN | CHEMBL53463 | |
| TP53 | CGI | MK-1775 | AZD-1775 | CHEMBL1976040 | |
| TP53 | CKB | Paclitaxel | PACLITAXEL | CHEMBL428647 | |
| TP53 | NCI | ZINC CHLORIDE | ZINC CHLORIDE | CHEMBL1200679 | |
| TP53 | CKB | PD-0325901 | PD-0325901 | CHEMBL507361 | |
| TP53 | CKB | PK11007 | |||
| TP53 | CKB | Temozolomide | TEMOZOLOMIDE | CHEMBL810 | |
| TP53 | CKB | TC-A2317 | |||
| TP53 | CKB | NU6027 | CHEMBL303958 | CHEMBL303958 | |
| TP53 | NCI | DAB | |||
| TP53 | CKB | IGF-1R antibody | |||
| TP53 | CKB | PT2399 | |||
| TP53 | CKB | Ifosfamide | IFOSFAMIDE | CHEMBL1024 | |
| TP53 | CIViC | SELUMETINIB (AZD6244) | SELUMETINIB | CHEMBL1614701 | |
| TP53 | CKB | EGFR antibody | |||
| TP53 | NCI | IL-12 | PROXYPHYLLINE | CHEMBL37390 | |
| TP53 | NCI | METHIMAZOLE | METHIMAZOLE | CHEMBL1515 | |
| TP53 | CKB | Cytarabine | CYTARABINE | CHEMBL803 | |
| TP53 | TTD | activator | CURAXIN CBLC102 | ||
| TP53 | CGI | Pramlintide | PRAMLINTIDE | CHEMBL2103758 | |
| TP53 | CIViC | CAPECITABINE | CAPECITABINE | CHEMBL1773 | |
| TP53 | CKB | Docetaxel | DOCETAXEL | CHEMBL92 | |
| TP53 | NCI | PROPYLTHIOURACIL | PROPYLTHIOURACIL | CHEMBL1518 | |
| TP53 | CKB | Ibrutinib | IBRUTINIB | CHEMBL1873475 | |
| TP53 | CKB | INC280 | CAPMATINIB | CHEMBL3188267 | |
| TP53 | CKB | Prodigiosin | PRODIGIOSIN | CHEMBL275787 | |
| TP53 | CKB | CGM097 | |||
| TP53 | CKB | SRA737 | |||
| TP53 | NCI | PUROMYCIN | PUROMYCIN | CHEMBL469912 | |
| TP53 | CKB | ABT-737 | CHEMBL376408 | CHEMBL376408 | |
| TP53 | CKB | Crizotinib | CRIZOTINIB | CHEMBL601719 | |
| TP53 | NCI | RAPAMYCIN | SIROLIMUS | CHEMBL413 | |
| TP53 | CKB | AZD6738 | AZD-6738 | CHEMBL3545178 | |
| TP53 | CKB | p53-SLP vaccine | |||
| TP53 | CKB | Irinotecan | IRINOTECAN | CHEMBL481 | |
| TP53 | NCI | TRIETHYLENETHIOPHOSPHORAMIDE | THIOTEPA | CHEMBL671 | |
| TP53 | NCI | GARLIC | GARLIC | CHEMBL2108463 | |
| TP53 | CKB | MK-8745 | |||
| TP53 | CIViC | AMGMDS3 | |||
| TP53 | CKB | Erlotinib | ERLOTINIB | CHEMBL553 | |
| TP53 | CKB | Pembrolizumab | PEMBROLIZUMAB | CHEMBL3137343 | |
| TP53 | NCI | VEGF | BEVACIZUMAB | CHEMBL1201583 | |
| TP53 | CKB | AMG 232 | |||
| TP53 | CKB | BEZ235 | DACTOLISIB | CHEMBL1879463 | |
| TP53 | CKB | Vemurafenib | VEMURAFENIB | CHEMBL1229517 | |
| TP53 | CKB | YW3-56 | |||
| TP53 | CKB | SAR405838 | |||
| TP53 | CGI | Cisplatin | |||
| TP53 | CGI | Abemaciclib | ABEMACICLIB | CHEMBL3301610 | |
| TP53 | CKB | PF-00477736 | PF-00477736 | CHEMBL3545137 | |
| TP53 | CKB | AMG 900 | AMG-900 | CHEMBL2140408 | |
| TP53 | CKB | GSK2830371 | |||
| TP53 | CKB | unspecified IGF-1R antibody | |||
| TP53 | NCI | DNA VACCINE | |||
| TP53 | CKB | Doxil | |||
| TP53 | CKB | AMG 337 | AMG-337 | CHEMBL3545212 | |
| TP53 | CKB | AZD6482 | AZD-6482 | CHEMBL2165191 | |
| TP53 | CGI | Decitabine | DECITABINE | CHEMBL1201129 | |
| TP53 | CIViC | NUTLIN-3A | |||
| TP53 | CKB | Bevacizumab | BEVACIZUMAB | CHEMBL1201583 | |
| TP53 | NCI | TRIFLUOPERAZINE | TRIFLUOPERAZINE | CHEMBL422 | |
| TP53 | CIViC | TAMOXIFEN | TAMOXIFEN | CHEMBL83 | |
| TP53 | CIViC | DOCETAXEL | DOCETAXEL | CHEMBL92 | |
| TP53 | CKB | ERBB3 antibody | |||
| TP53 | CKB | Tanespimycin | TANESPIMYCIN | CHEMBL109480 | |
| TP53 | CKB | JQ1 | |||
| TP53 | CKB | R547 | RG-547 | CHEMBL384304 | |
| TP53 | CKB | Selumetinib | SELUMETINIB | CHEMBL1614701 | |
| TP53 | CGI | AZD6738 | AZD-6738 | CHEMBL3545178 | |
| TP53 | CKB | Olaparib | OLAPARIB | CHEMBL521686 | |
| TP53 | NCI | TIRAPAZAMINE | TIRAPAZAMINE | CHEMBL50882 | |
| TP53 | CIViC | CISPLATIN | |||
| TP53 | CKB | Trifluridine | TRIFLURIDINE | CHEMBL1129 | |
| TP53 | CIViC | DOXORUBICIN | DOXORUBICIN | CHEMBL53463 | |
| TP53 | CKB | Epirubicin | EPIRUBICIN | CHEMBL417 | |
| TP53 | CKB | Radiotherapy | |||
| TP53 | CKB | NSC59984 | |||
| TP53 | CKB | Duvelisib | DUVELISIB | CHEMBL3039502 | |
| TP53 | CIViC | CETUXIMAB | CETUXIMAB | CHEMBL1201577 | |
| TP53 | NCI | MPA | MYCOPHENOLIC ACID | CHEMBL866 | |
| TP53 | CKB | Vorinostat | VORINOSTAT | CHEMBL98 | |
| TP53 | CKB | Alvespimycin | ALVESPIMYCIN | CHEMBL383824 | |
| TP53 | CKB | Daunoxome | |||
| TP53 | CKB | APR-246 | |||
| TP53 | CKB | Cyclophosphamide | CYCLOPHOSPHAMIDE | CHEMBL88 | |
| TP53 | CKB | APG-115 | |||
| TP53 | CKB | AZD2461 | |||
| TP53 | CKB | unspecified ERBB3 antibody | |||
| TP53 | CKB | MI-63 | |||
| TP53 | CIViC | CHEMOTHERAPY | |||
| TP53 | CKB | AZD5363 | AZD-5363 | CHEMBL2178577 | |
| TP53 | CKB | MLN0128 | INK-128 | CHEMBL3545056 | |
| TP53 | CKB | Nutlin-3a | |||
| TP53 | CKB | Dasatinib | DASATINIB | CHEMBL1421 | |
| TP53 | CKB | Carboplatin | CARBOPLATIN | CHEMBL1351 | |
| TP53 | NCI | CISPLATIN | |||
| TP53 | CKB | Sapanisertib | INK-128 | CHEMBL3545056 | |
| TP53 | CKB | NSC319726 | |||
| TP53 | CKB | p28 | |||
| TP53 | CKB | Dabrafenib | DABRAFENIB | CHEMBL2028663 | |
| TP53 | NCI | CAROTENOID | |||
| TP53 | CKB | DS-7423 | DS-7423 | CHEMBL3545248 | |
| TP53 | CKB | ONC201 | |||
| TP53 | CKB | Camptosar | |||
| TP53 | CKB | Ganetespib | GANETESPIB | CHEMBL2103879 | |
| TP53 | CKB | RO6839921 | |||
| TP53 | CKB | LY3009120 | LY-3009120 | CHEMBL3545195 | |
| TP53 | CKB | Ad.p53-DC vaccine | |||
| TP53 | CKB | Flourouracil | |||
| TP53 | NCI | RITUXIMAB | RITUXIMAB | CHEMBL1201576 | |
| TP53 | NCI | SAPONIN | |||
| TP53 | NCI | MCP-1 | |||
| TP53 | NCI | DES | DIETHYLSTILBESTROL | CHEMBL411 | |
| TP53 | NCI | R-FLURBIPROFEN | TARENFLURBIL | CHEMBL190083 | |
| TP53 | NCI | HALOPERIDOL | HALOPERIDOL | CHEMBL54 | |
| TP53 | CKB | PF-04217903 | PF-04217903 | CHEMBL2001019 | |
| TP53 | CKB | Oxaliplatin | OXALIPLATIN | CHEMBL414804 | |
| TP53 | CKB | Serdemetan | |||
| TP53 | TALC | inhibitor | BORTEZOMIB | BORTEZOMIB | CHEMBL325041 |
| TP53 | CKB | CPUY201112 | |||
| TP53 | CKB | MVAp53 | |||
| TP53 | CKB | Pazopanib | PAZOPANIB | CHEMBL477772 | |
| TP53 | CGI | Mitomycin C | MITOMYCIN | CHEMBL105 | |
| TP53 | NCI | FAS LIGAND | RIZATRIPTAN | CHEMBL905 | |
| TP53 | CKB | thioureidobutyronitrile | |||
| TP53 | CKB | Alpelisib | ALPELISIB | CHEMBL2396661 | |
| TP53 | CKB | Nutlin-3 | NUTLIN-3 | CHEMBL191334 | |
| TP53 | CKB | Abemaciclib | ABEMACICLIB | CHEMBL3301610 | |
| TP53 | CKB | Navitoclax | NAVITOCLAX | CHEMBL443684 | |
| TP53 | CKB | PF-06463922 | LORLATINIB | CHEMBL3286830 | |
| TP53 | CIViC | ADJUVANT CHEMOTHERAPY | |||
| TP53 | CKB | ALRN-6924 | |||
| TP53 | CKB | GDC-0425 | RG-7602 | CHEMBL3545007 | |
| TP53 | CKB | SP600125 | SP-600125 | CHEMBL1725279 | |
| TP53 | CKB | MPI-0479605 | HEMICHOLINIUM-3 | CHEMBL268697 | |
| TP53 | CKB | Avastin | BEVACIZUMAB | CHEMBL1201583 | |
| TP53 | NCI | VESNARINONE | VESNARINONE | CHEMBL17423 | |
| TP53 | CKB | EMD 1214063 | Tepotinib | CHEMBL3402762 | |
| TP53 | CKB | Pimasertib | PIMASERTIB | CHEMBL2107832 | |
| TP53 | CKB | RG7112 | |||
| TP53 | CKB | LB-100 | |||
| TP53 | CKB | ||||
| TP53 | CKB | AZD7762 | AZD-7762 | CHEMBL2041933 | |
| TP53 | CKB | HDM201 | |||
| TP53 | NCI | L-744,832 | CHEMBL1221512 | CHEMBL1221512 | |
| TP53 | CKB | PF-05212384 | GEDATOLISIB | CHEMBL592445 | |
| TP53 | CKB | Etoposide | ETOPOSIDE | CHEMBL44657 | |
| TP53 | CKB | ReACp53 | |||
| TP53 | NCI | ENALAPRIL | ENALAPRIL | CHEMBL578 | |
| TP53 | NCI | SELECTIVE ESTROGEN RECEPTOR MODULATORS | |||
| TP53 | CKB | unspecified EGFR antibody | |||
| TP53 | CKB | MK-1775 | AZD-1775 | CHEMBL1976040 | |
| TP53 | CGI | Doxorubicin | DOXORUBICIN | CHEMBL53463 | |
| TP53 | CKB | LY411575 | CHEMBL392068 | CHEMBL392068 | |
| TP53 | CKB | PI-3065 | |||
| TP53 | CGI | Gemcitabine | GEMCITABINE | CHEMBL888 | |
| TP53 | NCI | METHYLPREDNISOLONE | METHYLPREDNISOLONE | CHEMBL650 | |
| TP53 | CIViC | CARBOPLATIN | CARBOPLATIN | CHEMBL1351 | |
| TP53 | CKB | Demcizumab | DEMCIZUMAB | CHEMBL2109384 | |
| TP53 | CIViC | RG7112 | |||
| TP53 | CKB | Sirolimus | SIROLIMUS | CHEMBL413 | |
| TP53 | NCI | INTERFERON ALPHA-2B | INTERFERON ALFA-2B | CHEMBL1201558 | |
| TP53 | CKB | Daunorubicin | DAUNORUBICIN | CHEMBL178 | |
| TP53 | NCI | GOSSYPOL | GOSSYPOL | CHEMBL51483 | |
| TP53 | CKB | BLZ945 | |||
| TP53 | CKB | PHA-680632 | PHA-680632 | CHEMBL363160 | |
| TP53 | CKB | Topotecan | TOPOTECAN | CHEMBL84 | |
| TP53 | CKB | 7RH | |||
| TP53 | CKB | LGX818 | ENCORAFENIB | CHEMBL3301612 | |
| TP53 | NCI | INOSITOL | INOSITOL | CHEMBL1222251 | |
| TP53 | TALC | vaccine | EP-2101 | ||
| TP53 | CIViC | OXALIPLATIN | OXALIPLATIN | CHEMBL414804 | |
| TP53 | CKB | ABT-263 | NAVITOCLAX | CHEMBL443684 | |
| TP53 | CKB | MK-8242 | |||
| TP53 | CKB | VX-970 | VX-970 | CHEMBL3545202 | |
| TP53 | CKB | CP-31398 | |||
| TP53 | NCI | URSODEOXYCHOLIC ACID | URSODIOL | CHEMBL1551 | |
| TP53 | CKB | Ad5CMV-p53 gene | |||
| TP53 | NCI | PACLITAXEL | PACLITAXEL | CHEMBL428647 | |
| TP53 | CKB | CEP-8983 | |||
| TP53 | CKB | Panitumumab | PANITUMUMAB | CHEMBL1201827 | |
| TP53 | NCI | STREPTONIGRIN | STREPTONIGRIN | CHEMBL11417 | |
| TP53 | CKB | Seliciclib | SELICICLIB | CHEMBL14762 | |
| TP53 | CKB | PD0166285 |
Phenotype
Protein
Drug