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The Cancer Genome Atlas (TCGA) International Cancer Genome Consortium (ICGC) The Cancer Cell Line Encyclopedia (CCLE)
Genomics England (GEL) Spatial Characterisation
User Guide
  1. Publicly Available Data

The Cancer Genome Atlas

Powered by SNPnexus


Summary
Clinical Summary Genomics Transcriptomics Cohort Browser Details
Overview Help
Sex
Survival Status
Race
ER Status
HER2 Status
Survival Time (Years)
Age at Diagnosis
Genetic Ancestry
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Cohort Summary Variant Identification Drug Prediction Interactions & Pathways
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Genomics Summary
Oncoplot help
Oncoplot
LolliPlot help
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LolliPlot
Somatic Interactions help
Somatic Interactions
Cancer Genome Interpreter (CGI) help
CGI Biomarker CGI Bioactivity
Gene Protein Alteration Alteration Match Drug Effect Tumour Evidence
BRCA1 Q934* Complete Match Chemotherapy (PARP inhibitor;Chemotherapy) Responsive OV Early trials
BRCA1 Q934* Complete Match PARP inhibitor Responsive BRCA Early trials
BRCA1 Q934* Complete Match PARP inhibitor;Chemotherapy Responsive OV Early trials
BRCA1 Q934* Complete Match Rucaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 Q934* Complete Match Platinum Agent (Chemotherapy) Responsive BRCA Early trials
BRCA1 Q934* Complete Match WEE1 inhibitor Responsive CANCER Case report
BRCA1 Q934* Complete Match Platinum Agent (Chemotherapy) Responsive OV Late trials
BRCA1 Q934* Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
BRCA1 Q934* Complete Match Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) Responsive BRCA Early trials
BRCA1 Q934* Complete Match PARP inhibitor Responsive PA Case report
BRCA1 Q934* Complete Match Olaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 Q934* Different Alteration PARP inhibitor Responsive OV Pre-clinical
ARID1A Q944* Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A Q944* Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A Q944* Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A Q944* Complete Match ATR inhibitor Responsive CANCER Pre-clinical
PIK3CA H1047L Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA H1047L Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA H1047L Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA H1047L Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA H1047L Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA H1047L Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA H1047L Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA H1047L Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA H1047L Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA H1047L Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA H1047L Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA H1047L Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA H1047L Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA H1047L Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
CDH1 Q23* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
ROS1 P194S Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 P194S Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 P194S Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 P194S Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 P194S Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
CDH1 R63* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
NF1 R366* Different Mutation Vemurafenib (BRAF inhibitor) Resistant CM Pre-clinical
NF1 R366* Different Mutation Everolimus (MTOR inhibitor) Responsive HNC Case report
NF1 R366* Complete Match Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 R366* Complete Match Vinblastine (Chemotherapy) Responsive G Early trials
NF1 R366* Complete Match KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 R366* Complete Match Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 R366* Complete Match Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 R366* Complete Match Retinoic Acid Resistant NB Pre-clinical
NF1 R366* Complete Match Everolimus (MTOR inhibitor) Responsive NF Late trials
NF1 R366* Complete Match Trametinib (MEK inhibitor) Responsive G Case report
NF1 R366* Complete Match Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 R366* Complete Match Nilotinib (BCR-ABL inhibitor) Responsive MPN, PLEN Pre-clinical
NF1 R366* Complete Match MEK inhibitor Responsive MPN Pre-clinical
NF1 R366* Complete Match Everolimus (MTOR inhibitor) Responsive HNC, SG Case report
NF1 R366* Complete Match Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 R366* Complete Match PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 R366* Complete Match MEK inhibitor Responsive LK, G Pre-clinical
NF1 R366* Complete Match Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 R366* Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 R366* Complete Match AURK inhibitor Responsive MPN Pre-clinical
NF1 R366* Complete Match MTOR inhibitor Responsive LK, G, MPN Pre-clinical
NF1 R366* Complete Match Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 R366* Complete Match Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) Responsive HC Case report
NF1 R366* Complete Match Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 R366* Complete Match Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 R366* Complete Match PD1 Ab inhibitor Responsive CM Early trials
NF1 R366* Complete Match Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 R366* Complete Match Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 R366* Complete Match Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 R366* Complete Match BRD4 inhibitor Responsive MPN Pre-clinical
NF1 R366* Complete Match Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 R366* Complete Match Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 R366* Complete Match MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 R366* Complete Match Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 R366* Complete Match Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 R366* Complete Match Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 R366* Different Alteration MTOR inhibitor Responsive MPN, G, LK Pre-clinical
NF1 R366* Different Alteration PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 R366* Different Alteration Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 R366* Different Alteration Trametinib (MEK inhibitor) Responsive G Case report
NF1 R366* Different Alteration BRD4 inhibitor Responsive MPN Pre-clinical
NF1 R366* Different Alteration Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 R366* Different Alteration Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 R366* Different Alteration Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 R366* Different Alteration MEK inhibitor Responsive G, LK Pre-clinical
NF1 R366* Different Alteration Vinblastine (Chemotherapy) Responsive G Early trials
NF1 R366* Different Alteration Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 R366* Different Alteration Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 R366* Different Alteration Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 R366* Different Alteration MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 R366* Different Alteration Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 R366* Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 R366* Different Alteration Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 R366* Different Alteration Everolimus (MTOR inhibitor) Responsive SG, HNC Case report
NF1 R366* Different Alteration Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 R366* Different Alteration Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 R366* Different Alteration Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 R366* Different Alteration Retinoic Acid Resistant NB Pre-clinical
NF1 R366* Different Alteration Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 R366* Different Alteration Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 R366* Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive PLEN, MPN Pre-clinical
NF1 R366* Different Alteration Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 R366* Different Alteration Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 R366* Different Alteration AURK inhibitor Responsive MPN Pre-clinical
NF1 R366* Different Alteration Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 R366* Different Alteration PD1 Ab inhibitor Responsive CM Early trials
NF1 R366* Different Alteration MEK inhibitor Responsive MPN Pre-clinical
NF1 R366* Different Alteration KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
PIK3CA E542K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E542K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E542K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E542K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E542K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E542K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E542K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E542K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E542K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E542K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E542K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E542K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E542K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E542K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
ARID1A Q479* Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A Q479* Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A Q479* Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A Q479* Complete Match ATR inhibitor Responsive CANCER Pre-clinical
ERBB2 V777L Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 V777L Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BRCA FDA guidelines
ERBB2 V777L Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, BRCA, GEJA FDA guidelines
ERBB2 V777L Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 V777L Different Alteration MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) Responsive SOLID Early trials
ERBB2 V777L Complete Match Lapatinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 V777L Complete Match Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 V777L Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER, BRCA Pre-clinical
ERBB2 V777L Different Mutation Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 V777L Complete Match Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 V777L Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Case report
ERBB2 V777L Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA, LUAD Case report
ERBB2 V777L Different Mutation Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive L Early trials
ERBB2 V777L Different Mutation Neratinib (ERBB2 inhibitor) Resistant BRCA Case report
ERBB2 V777L Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Pre-clinical
ERBB2 V777L Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Case report
ERBB2 V777L Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 V777L Different Mutation Lapatinib (ERBB2 inhibitor) Resistant BRCA Pre-clinical
ERBB2 V777L Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB2 V777L Complete Match Temsirolimus (MTOR inhibitor) Responsive LUAD Early trials
ERBB2 V777L Complete Match Dacomitinib (Pan ERBB inhibitor) Responsive NSCLC Early trials
ERBB2 V777L Complete Match Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 V777L Different Mutation ERBB2 inhibitor Responsive LUAD Early trials
ERBB2 V777L Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Early trials
ERBB2 V777L Different Mutation ERBB2 mAb inhibitor Responsive LUAD Early trials
ERBB2 V777L Different Mutation Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 V777L Different Mutation Lapatinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 V777L Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Early trials
ERBB2 V777L Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Late trials
ERBB2 V777L Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 V777L Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive COREAD Late trials
ERBB2 V777L Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive OV Early trials
ERBB2 V777L Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB2 V777L Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive COREAD Case report
ERBB2 V777L Different Alteration Rociletinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 V777L Different Alteration Osimertinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 V777L Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 V777L Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
ERBB2 V777L Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BT Early trials
ERBB2 V777L Different Alteration Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) Responsive BRCA Early trials
ERBB2 V777L Different Alteration HER2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 V777L Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 V777L Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive ST Early trials
ERBB2 V777L Different Alteration Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) Responsive BRCA Early trials
ERBB2 V777L Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, GEJA FDA guidelines
ERBB2 V777L Different Alteration ERBB2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 V777L Different Alteration Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 V777L Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive HNC Case report
ERBB2 V777L Different Alteration Neratinib (ERBB2 inhibitor) Responsive BRCA Late trials
ERBB2 V777L Different Alteration Trastuzumab (ERBB2 mAb inhibitor) No Responsive ED Early trials
ERBB2 V777L Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive ED Pre-clinical
ERBB2 V777L Different Alteration Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) Responsive ST Early trials
ERBB2 V777L Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive ST Case report
ERBB2 V777L Different Alteration EGFR inhibitor Resistant LUAD Pre-clinical
CDH1 splice_donor_variant Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
RB1 S829* Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 S829* Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 S829* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 S829* Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 S829* Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 S829* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 S829* Different Alteration HDAC inhibitor Responsive RB Pre-clinical
TP53 R175H Complete Match HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R175H Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R175H Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R175H Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R175H Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R175H Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R175H Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R175H Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R175H Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R175H Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R175H Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R175H Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R175H Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R175H Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R175H Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA H1047R), PIK3CA MUT (E726K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA H1047R), PIK3CA MUT (E726K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA H1047R), PIK3CA MUT (E726K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
AKT3 L151F Different Alteration ATP competitive AKT inhibitor Responsive BRCA Pre-clinical
ARID1A Q393* Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A Q393* Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A Q393* Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A Q393* Complete Match ATR inhibitor Responsive CANCER Pre-clinical
ERCC4 R8* Complete Match Cisplatin (Chemotherapy) Responsive OV Pre-clinical
NF1 Q535* Different Mutation Vemurafenib (BRAF inhibitor) Resistant CM Pre-clinical
NF1 Q535* Different Mutation Everolimus (MTOR inhibitor) Responsive HNC Case report
NF1 Q535* Complete Match Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 Q535* Complete Match Vinblastine (Chemotherapy) Responsive G Early trials
NF1 Q535* Complete Match KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 Q535* Complete Match Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 Q535* Complete Match Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 Q535* Complete Match Retinoic Acid Resistant NB Pre-clinical
NF1 Q535* Complete Match Everolimus (MTOR inhibitor) Responsive NF Late trials
NF1 Q535* Complete Match Trametinib (MEK inhibitor) Responsive G Case report
NF1 Q535* Complete Match Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 Q535* Complete Match Nilotinib (BCR-ABL inhibitor) Responsive MPN, PLEN Pre-clinical
NF1 Q535* Complete Match MEK inhibitor Responsive MPN Pre-clinical
NF1 Q535* Complete Match Everolimus (MTOR inhibitor) Responsive HNC, SG Case report
NF1 Q535* Complete Match Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 Q535* Complete Match PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 Q535* Complete Match MEK inhibitor Responsive LK, G Pre-clinical
NF1 Q535* Complete Match Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 Q535* Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 Q535* Complete Match AURK inhibitor Responsive MPN Pre-clinical
NF1 Q535* Complete Match MTOR inhibitor Responsive LK, G, MPN Pre-clinical
NF1 Q535* Complete Match Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 Q535* Complete Match Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) Responsive HC Case report
NF1 Q535* Complete Match Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 Q535* Complete Match Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 Q535* Complete Match PD1 Ab inhibitor Responsive CM Early trials
NF1 Q535* Complete Match Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 Q535* Complete Match Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 Q535* Complete Match Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 Q535* Complete Match BRD4 inhibitor Responsive MPN Pre-clinical
NF1 Q535* Complete Match Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 Q535* Complete Match Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 Q535* Complete Match MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 Q535* Complete Match Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 Q535* Complete Match Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 Q535* Complete Match Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 Q535* Different Alteration MTOR inhibitor Responsive MPN, G, LK Pre-clinical
NF1 Q535* Different Alteration PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 Q535* Different Alteration Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 Q535* Different Alteration Trametinib (MEK inhibitor) Responsive G Case report
NF1 Q535* Different Alteration BRD4 inhibitor Responsive MPN Pre-clinical
NF1 Q535* Different Alteration Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 Q535* Different Alteration Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 Q535* Different Alteration Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 Q535* Different Alteration MEK inhibitor Responsive G, LK Pre-clinical
NF1 Q535* Different Alteration Vinblastine (Chemotherapy) Responsive G Early trials
NF1 Q535* Different Alteration Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 Q535* Different Alteration Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 Q535* Different Alteration Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 Q535* Different Alteration MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 Q535* Different Alteration Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 Q535* Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 Q535* Different Alteration Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 Q535* Different Alteration Everolimus (MTOR inhibitor) Responsive SG, HNC Case report
NF1 Q535* Different Alteration Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 Q535* Different Alteration Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 Q535* Different Alteration Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 Q535* Different Alteration Retinoic Acid Resistant NB Pre-clinical
NF1 Q535* Different Alteration Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 Q535* Different Alteration Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 Q535* Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive PLEN, MPN Pre-clinical
NF1 Q535* Different Alteration Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 Q535* Different Alteration Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 Q535* Different Alteration AURK inhibitor Responsive MPN Pre-clinical
NF1 Q535* Different Alteration Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 Q535* Different Alteration PD1 Ab inhibitor Responsive CM Early trials
NF1 Q535* Different Alteration MEK inhibitor Responsive MPN Pre-clinical
NF1 Q535* Different Alteration KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
ESR1 Q17H Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
JAK2 R133P Different Alteration Ruxolitinib (JAK inhibitor) Responsive ALL Pre-clinical
BRAF S112C Different Alteration Sorafenib (Pan-TK inhibitor) Responsive CM, LUAD, PRAD Pre-clinical
BRAF S112C Different Alteration MEK inhibitor Responsive LUAD, CM, PRAD Pre-clinical
BRAF S112C Different Alteration Selumetinib (MEK inhibitor) Responsive OV Case report
BRAF S112C Different Alteration BRAF inhibitor;MEK inhibitor Responsive LUAD Case report
SETD2 S461* Complete Match WEE1 inhibitor Responsive CANCER Pre-clinical
SETD2 S461* Different Alteration WEE1 inhibitor Responsive CANCER Pre-clinical
PIK3CA E542K), PIK3CA MUT (R88Q Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E542K), PIK3CA MUT (R88Q Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E542K), PIK3CA MUT (R88Q Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
PML intron_variant Different Alteration Volasertib (PLK1 inhibitor) Responsive AML Early trials
PML intron_variant Different Alteration Tretinoin (Retinoid) Responsive APML FDA guidelines
PML intron_variant Different Alteration Tretinoin;Arsenic Trioxide (Retinoid;Chemotherapy) Responsive AML FDA guidelines
NF1 W571* Different Mutation Vemurafenib (BRAF inhibitor) Resistant CM Pre-clinical
NF1 W571* Different Mutation Everolimus (MTOR inhibitor) Responsive HNC Case report
NF1 W571* Complete Match Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 W571* Complete Match Vinblastine (Chemotherapy) Responsive G Early trials
NF1 W571* Complete Match KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 W571* Complete Match Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 W571* Complete Match Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 W571* Complete Match Retinoic Acid Resistant NB Pre-clinical
NF1 W571* Complete Match Everolimus (MTOR inhibitor) Responsive NF Late trials
NF1 W571* Complete Match Trametinib (MEK inhibitor) Responsive G Case report
NF1 W571* Complete Match Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 W571* Complete Match Nilotinib (BCR-ABL inhibitor) Responsive MPN, PLEN Pre-clinical
NF1 W571* Complete Match MEK inhibitor Responsive MPN Pre-clinical
NF1 W571* Complete Match Everolimus (MTOR inhibitor) Responsive HNC, SG Case report
NF1 W571* Complete Match Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 W571* Complete Match PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 W571* Complete Match MEK inhibitor Responsive LK, G Pre-clinical
NF1 W571* Complete Match Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 W571* Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 W571* Complete Match AURK inhibitor Responsive MPN Pre-clinical
NF1 W571* Complete Match MTOR inhibitor Responsive LK, G, MPN Pre-clinical
NF1 W571* Complete Match Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 W571* Complete Match Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) Responsive HC Case report
NF1 W571* Complete Match Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 W571* Complete Match Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 W571* Complete Match PD1 Ab inhibitor Responsive CM Early trials
NF1 W571* Complete Match Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 W571* Complete Match Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 W571* Complete Match Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 W571* Complete Match BRD4 inhibitor Responsive MPN Pre-clinical
NF1 W571* Complete Match Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 W571* Complete Match Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 W571* Complete Match MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 W571* Complete Match Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 W571* Complete Match Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 W571* Complete Match Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 W571* Different Alteration MTOR inhibitor Responsive MPN, G, LK Pre-clinical
NF1 W571* Different Alteration PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 W571* Different Alteration Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 W571* Different Alteration Trametinib (MEK inhibitor) Responsive G Case report
NF1 W571* Different Alteration BRD4 inhibitor Responsive MPN Pre-clinical
NF1 W571* Different Alteration Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 W571* Different Alteration Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 W571* Different Alteration Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 W571* Different Alteration MEK inhibitor Responsive G, LK Pre-clinical
NF1 W571* Different Alteration Vinblastine (Chemotherapy) Responsive G Early trials
NF1 W571* Different Alteration Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 W571* Different Alteration Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 W571* Different Alteration Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 W571* Different Alteration MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 W571* Different Alteration Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 W571* Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 W571* Different Alteration Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 W571* Different Alteration Everolimus (MTOR inhibitor) Responsive SG, HNC Case report
NF1 W571* Different Alteration Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 W571* Different Alteration Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 W571* Different Alteration Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 W571* Different Alteration Retinoic Acid Resistant NB Pre-clinical
NF1 W571* Different Alteration Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 W571* Different Alteration Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 W571* Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive PLEN, MPN Pre-clinical
NF1 W571* Different Alteration Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 W571* Different Alteration Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 W571* Different Alteration AURK inhibitor Responsive MPN Pre-clinical
NF1 W571* Different Alteration Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 W571* Different Alteration PD1 Ab inhibitor Responsive CM Early trials
NF1 W571* Different Alteration MEK inhibitor Responsive MPN Pre-clinical
NF1 W571* Different Alteration KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
TP53 V272M Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 V272M Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 V272M Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 V272M Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 V272M Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 V272M Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 V272M Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V272M Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V272M Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 V272M Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 V272M Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 V272M Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V272M Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 V272M Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V272M Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA H1047R Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA H1047R Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA H1047R Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA H1047R Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA H1047R Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA H1047R Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA H1047R Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA H1047R Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA H1047R Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA H1047R Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA H1047R Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA H1047R Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA H1047R Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA H1047R Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
TP53 M133K Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 M133K Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 M133K Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 M133K Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 M133K Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 M133K Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 M133K Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 M133K Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 M133K Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 M133K Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 M133K Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 M133K Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 M133K Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 M133K Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 M133K Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA G118D Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA G118D Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA G118D Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA G118D Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA G118D Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA G118D Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA G118D Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA G118D Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA G118D Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA G118D Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA G118D Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA G118D Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA G118D Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA G118D Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
KMT2A V3015I Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A V3015I Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A V3015I Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A V3015I Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A V3015I Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A V3015I Different Alteration DOT1L inhibitor Responsive AML Early trials
PIK3CA E542K), PIK3CA MUT (M1004I Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E542K), PIK3CA MUT (M1004I Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E542K), PIK3CA MUT (M1004I Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
TP53 R196* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R196* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R196* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R196* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R196* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R196* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R196* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R196* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R196* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R196* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R196* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R196* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R196* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R196* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R196* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
AKT3 L274L Different Alteration ATP competitive AKT inhibitor Responsive BRCA Pre-clinical
PIK3CA G1049R Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA G1049R Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA G1049R Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA G1049R Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA G1049R Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA G1049R Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA G1049R Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA G1049R Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA G1049R Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA G1049R Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA G1049R Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA G1049R Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA G1049R Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA G1049R Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
CHEK2 Q69* Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
CHEK2 Q69* Different Alteration Olaparib (PARP inhibitor) Responsive PRAD Early trials
PTPRD L1535* Complete Match IGF1R inhibitor Responsive S Case report
TP53 S183* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 S183* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 S183* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 S183* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 S183* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 S183* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 S183* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 S183* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 S183* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 S183* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 S183* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 S183* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 S183* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 S183* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 S183* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R273L Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R273L Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R273L Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R273L Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R273L Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R273L Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R273L Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R273L Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R273L Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R273L Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R273L Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R273L Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R273L Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R273L Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R273L Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
BRCA1 splice_donor_variant Complete Match Chemotherapy (PARP inhibitor;Chemotherapy) Responsive OV Early trials
BRCA1 splice_donor_variant Complete Match PARP inhibitor Responsive BRCA Early trials
BRCA1 splice_donor_variant Complete Match PARP inhibitor;Chemotherapy Responsive OV Early trials
BRCA1 splice_donor_variant Complete Match Rucaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 splice_donor_variant Complete Match Platinum Agent (Chemotherapy) Responsive BRCA Early trials
BRCA1 splice_donor_variant Complete Match WEE1 inhibitor Responsive CANCER Case report
BRCA1 splice_donor_variant Complete Match Platinum Agent (Chemotherapy) Responsive OV Late trials
BRCA1 splice_donor_variant Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
BRCA1 splice_donor_variant Complete Match Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) Responsive BRCA Early trials
BRCA1 splice_donor_variant Complete Match PARP inhibitor Responsive PA Case report
BRCA1 splice_donor_variant Complete Match Olaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 splice_donor_variant Different Alteration PARP inhibitor Responsive OV Pre-clinical
TP53 Y220C Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Y220C Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Y220C Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Y220C Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Y220C Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Y220C Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Y220C Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y220C Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y220C Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Y220C Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Y220C Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Y220C Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y220C Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Y220C Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y220C Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NTRK1 L196M Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Case report
NTRK1 L196M Different Alteration Pan-TKR inhibitor Responsive CANCER Early trials
NTRK1 L196M Different Alteration Pan-TK inhibitor Responsive LUAD Pre-clinical
NTRK1 L196M Different Alteration Pan-TK inhibitor Responsive COREAD Case report
BRD4 3-UTRSNV Different Alteration BET inhibitor Responsive NMC Case report
FGFR2 V122M Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 V122M Different Alteration FGFR inhibitor Responsive BT Early trials
TP53 R273H), TP53 MUT (D208G Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R273H), TP53 MUT (D208G Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R273H), TP53 MUT (D208G Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R273H), TP53 MUT (D208G Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R273H), TP53 MUT (D208G Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R273H), TP53 MUT (D208G Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R273H), TP53 MUT (D208G Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R273H), TP53 MUT (D208G Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R273H), TP53 MUT (D208G Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R273H), TP53 MUT (D208G Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R273H), TP53 MUT (D208G Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R273H), TP53 MUT (D208G Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R273H), TP53 MUT (D208G Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R273H), TP53 MUT (D208G Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R273H), TP53 MUT (D208G Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
EGFR L792L Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR L792L Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
PIK3CA H1047Y Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA H1047Y Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA H1047Y Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA H1047Y Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA H1047Y Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA H1047Y Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA H1047Y Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA H1047Y Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA H1047Y Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA H1047Y Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA H1047Y Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA H1047Y Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA H1047Y Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA H1047Y Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
PIK3CA R88Q Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA R88Q Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA R88Q Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA R88Q Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA R88Q Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA R88Q Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA R88Q Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA R88Q Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA R88Q Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA R88Q Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA R88Q Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA R88Q Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA R88Q Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA R88Q Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
PTEN R130* Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN R130* Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN R130* Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN R130* Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN R130* Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN R130* Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN R130* Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN R130* Complete Match PARP inhibitor Responsive ED Case report
PTEN R130* Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN R130* Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN R130* Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN R130* Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN R130* Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN R130* Complete Match AKT inhibitor Responsive PA Case report
PTEN R130* Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN R130* Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN R130* Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN R130* Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN R130* Different Alteration PARP inhibitor Responsive ED Case report
PTEN R130* Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN R130* Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN R130* Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN R130* Different Alteration AKT inhibitor Responsive PA Case report
PTEN R130* Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN R130* Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
CDH1 G278* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
PIK3CA E545K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E545K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E545K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E545K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E545K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E545K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E545K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E545K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E545K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E545K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E545K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E545K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E545K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E545K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
TP53 Q331* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Q331* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Q331* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Q331* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Q331* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Q331* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Q331* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q331* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q331* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Q331* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Q331* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Q331* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q331* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Q331* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q331* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R273C Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R273C Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R273C Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R273C Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R273C Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R273C Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R273C Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R273C Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R273C Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R273C Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R273C Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R273C Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R273C Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R273C Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R273C Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
CDH1 Q511* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
BRCA2 Y3308* Complete Match PD1 Ab inhibitor Responsive CM Case report
BRCA2 Y3308* Complete Match Olaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA2 Y3308* Complete Match Platinum Agent (Chemotherapy) Responsive OV Late trials
BRCA2 Y3308* Complete Match Chemotherapy (PARP inhibitor;Chemotherapy) Responsive OV Early trials
BRCA2 Y3308* Complete Match PARP inhibitor;Chemotherapy Responsive OV Early trials
BRCA2 Y3308* Complete Match Platinum Agent (Chemotherapy) Responsive PA Case report
BRCA2 Y3308* Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
BRCA2 Y3308* Complete Match Rucaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA2 Y3308* Complete Match PD1/PDL1 inhibitor Responsive UTH Early trials
BRCA2 Y3308* Complete Match Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) Responsive BRCA Early trials
BRCA2 Y3308* Complete Match Platinum Agent (Chemotherapy) Responsive BRCA Early trials
BRCA2 Y3308* Complete Match PARP inhibitor Responsive BRCA Early trials
BRCA2 Y3308* Different Alteration PD1/PDL1 inhibitor Responsive UTH Early trials
BRCA2 Y3308* Different Alteration PARP inhibitor Responsive OV Pre-clinical
AKT3 G265R Different Alteration ATP competitive AKT inhibitor Responsive BRCA Pre-clinical
BCR T634T Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
BCR T634T Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
BCR T634T Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR T634T Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR T634T Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
BCR T634T Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
STAG2 G540* Complete Match PARP inhibitor Responsive G Pre-clinical
TP53 G199V Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 G199V Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 G199V Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 G199V Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 G199V Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 G199V Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 G199V Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G199V Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G199V Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 G199V Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 G199V Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 G199V Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G199V Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 G199V Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G199V Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
RB1 L206* Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 L206* Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 L206* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 L206* Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 L206* Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 L206* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 L206* Different Alteration HDAC inhibitor Responsive RB Pre-clinical
PIK3CA N345K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA N345K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA N345K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA N345K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA N345K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA N345K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA N345K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA N345K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA N345K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA N345K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA N345K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA N345K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA N345K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA N345K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
KMT2A S2872L Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A S2872L Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A S2872L Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A S2872L Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A S2872L Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A S2872L Different Alteration DOT1L inhibitor Responsive AML Early trials
BCR intron_variant Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
BCR intron_variant Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
BCR intron_variant Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR intron_variant Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR intron_variant Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
BCR intron_variant Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
TP53 Y234C Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Y234C Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Y234C Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Y234C Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Y234C Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Y234C Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Y234C Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y234C Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y234C Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Y234C Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Y234C Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Y234C Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y234C Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Y234C Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y234C Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
RNF43 S425* Complete Match Porcupine inhibitor Responsive COREAD Case report
NOTCH2 G2381G Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
NTRK3 L824L Different Alteration IGF1R inhibitor Responsive BRCA Pre-clinical
NTRK3 L824L Different Alteration PI3K pathway inhibitor Responsive BRCA Pre-clinical
NTRK3 L824L Different Alteration Midostaurin (Pan-TK inhibitor) Responsive BRCA Pre-clinical
SF3B1 K700E Complete Match Spliceosome inhibitor Responsive CANCER Pre-clinical
TP53 R342* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R342* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R342* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R342* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R342* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R342* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R342* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R342* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R342* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R342* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R342* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R342* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R342* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R342* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R342* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
KMT2A K3048T Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A K3048T Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A K3048T Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A K3048T Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A K3048T Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A K3048T Different Alteration DOT1L inhibitor Responsive AML Early trials
ATM R3047* Different Mutation AZD6738 (ATR inhibitor) Responsive BCL Early trials
ATM R3047* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
ATM R3047* Complete Match Olaparib (PARP inhibitor) Responsive ST, PRAD Early trials
ATM R3047* Complete Match PARP inhibitor Responsive ST Early trials
ATM R3047* Complete Match ATR inhibitor Responsive COREAD Case report
ATM R3047* Complete Match DNA-PKc inhibitor Responsive LY Pre-clinical
ATM R3047* Complete Match Temozolomide (Chemotherapy) Responsive G Pre-clinical
ATM R3047* Complete Match PD1/PDL1 inhibitor Responsive UTH Early trials
ATM R3047* Different Alteration PD1/PDL1 inhibitor Responsive UTH Early trials
ATM R3047* Different Alteration DNA-PKc inhibitor Responsive LY Pre-clinical
ATM R3047* Different Alteration PARP inhibitor Responsive ST Early trials
ATM R3047* Different Alteration ATR inhibitor Responsive COREAD Case report
ATM R3047* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
FBXW7 R479Q Complete Match Steroid Responsive ALL Late trials
FBXW7 R479Q Complete Match Tubulin inhibitor Resistant CANCER Pre-clinical
FBXW7 R479Q Different Alteration Sirolimus (MTOR inhibitor) Responsive COREAD Pre-clinical
FBXW7 R479Q Different Alteration Tubulin inhibitor Resistant CANCER Pre-clinical
BRCA2 L2926* Complete Match PD1 Ab inhibitor Responsive CM Case report
BRCA2 L2926* Complete Match Olaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA2 L2926* Complete Match Platinum Agent (Chemotherapy) Responsive OV Late trials
BRCA2 L2926* Complete Match Chemotherapy (PARP inhibitor;Chemotherapy) Responsive OV Early trials
BRCA2 L2926* Complete Match PARP inhibitor;Chemotherapy Responsive OV Early trials
BRCA2 L2926* Complete Match Platinum Agent (Chemotherapy) Responsive PA Case report
BRCA2 L2926* Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
BRCA2 L2926* Complete Match Rucaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA2 L2926* Complete Match PD1/PDL1 inhibitor Responsive UTH Early trials
BRCA2 L2926* Complete Match Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) Responsive BRCA Early trials
BRCA2 L2926* Complete Match Platinum Agent (Chemotherapy) Responsive BRCA Early trials
BRCA2 L2926* Complete Match PARP inhibitor Responsive BRCA Early trials
BRCA2 L2926* Different Alteration PD1/PDL1 inhibitor Responsive UTH Early trials
BRCA2 L2926* Different Alteration PARP inhibitor Responsive OV Pre-clinical
SMARCA4 E1611* Complete Match EZH2 inhibitor Responsive OVRT Case report
SMARCA4 E1611* Complete Match AURKA inhibitor Responsive NSCLC Pre-clinical
SMARCA4 E1611* Complete Match EZH2 inhibitor Responsive OV Case report
SMARCA4 E1611* Different Alteration EZH2 inhibitor Responsive OVRT Case report
SMARCA4 E1611* Different Alteration EZH2 inhibitor Responsive OV Case report
PDGFRA R981P Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive MDPS, MDS, ECL, HES FDA guidelines
CDH1 splice_acceptor_variant Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
PIK3CA Q546R Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA Q546R Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA Q546R Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA Q546R Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA Q546R Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA Q546R Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA Q546R Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA Q546R Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA Q546R Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA Q546R Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA Q546R Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA Q546R Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA Q546R Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA Q546R Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
ERBB2 L755W Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 L755W Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BRCA FDA guidelines
ERBB2 L755W Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, BRCA, GEJA FDA guidelines
ERBB2 L755W Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 L755W Different Alteration MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) Responsive SOLID Early trials
ERBB2 L755W Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 L755W Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 L755W Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER, BRCA Pre-clinical
ERBB2 L755W Different Mutation Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 L755W Complete Match Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 L755W Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Case report
ERBB2 L755W Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA, LUAD Case report
ERBB2 L755W Different Mutation Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive L Early trials
ERBB2 L755W Different Mutation Neratinib (ERBB2 inhibitor) Resistant BRCA Case report
ERBB2 L755W Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Pre-clinical
ERBB2 L755W Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Case report
ERBB2 L755W Different Mutation Lapatinib (ERBB2 inhibitor) Resistant BRCA Pre-clinical
ERBB2 L755W Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB2 L755W Complete Match Temsirolimus (MTOR inhibitor) Responsive LUAD Early trials
ERBB2 L755W Complete Match Dacomitinib (Pan ERBB inhibitor) Responsive NSCLC Early trials
ERBB2 L755W Complete Match Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 L755W Different Mutation ERBB2 inhibitor Responsive LUAD Early trials
ERBB2 L755W Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Early trials
ERBB2 L755W Different Mutation ERBB2 mAb inhibitor Responsive LUAD Early trials
ERBB2 L755W Different Mutation Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 L755W Different Mutation Lapatinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 L755W Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Early trials
ERBB2 L755W Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Late trials
ERBB2 L755W Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 L755W Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive COREAD Late trials
ERBB2 L755W Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive OV Early trials
ERBB2 L755W Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB2 L755W Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive COREAD Case report
ERBB2 L755W Different Alteration Rociletinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 L755W Different Alteration Osimertinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 L755W Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 L755W Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
ERBB2 L755W Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BT Early trials
ERBB2 L755W Different Alteration Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) Responsive BRCA Early trials
ERBB2 L755W Different Alteration HER2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 L755W Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 L755W Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive ST Early trials
ERBB2 L755W Different Alteration Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) Responsive BRCA Early trials
ERBB2 L755W Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, GEJA FDA guidelines
ERBB2 L755W Different Alteration ERBB2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 L755W Different Alteration Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 L755W Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive HNC Case report
ERBB2 L755W Different Alteration Neratinib (ERBB2 inhibitor) Responsive BRCA Late trials
ERBB2 L755W Different Alteration Trastuzumab (ERBB2 mAb inhibitor) No Responsive ED Early trials
ERBB2 L755W Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive ED Pre-clinical
ERBB2 L755W Different Alteration Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) Responsive ST Early trials
ERBB2 L755W Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive ST Case report
ERBB2 L755W Different Alteration EGFR inhibitor Resistant LUAD Pre-clinical
ERBB2 R678Q Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 R678Q Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BRCA FDA guidelines
ERBB2 R678Q Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, BRCA, GEJA FDA guidelines
ERBB2 R678Q Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 R678Q Different Alteration MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) Responsive SOLID Early trials
ERBB2 R678Q Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 R678Q Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 R678Q Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER, BRCA Pre-clinical
ERBB2 R678Q Different Mutation Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 R678Q Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Case report
ERBB2 R678Q Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA, LUAD Case report
ERBB2 R678Q Different Mutation Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive L Early trials
ERBB2 R678Q Different Mutation Neratinib (ERBB2 inhibitor) Resistant BRCA Case report
ERBB2 R678Q Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Pre-clinical
ERBB2 R678Q Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Case report
ERBB2 R678Q Different Mutation Lapatinib (ERBB2 inhibitor) Resistant BRCA Pre-clinical
ERBB2 R678Q Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB2 R678Q Complete Match Temsirolimus (MTOR inhibitor) Responsive LUAD Early trials
ERBB2 R678Q Complete Match Dacomitinib (Pan ERBB inhibitor) Responsive NSCLC Early trials
ERBB2 R678Q Complete Match Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 R678Q Different Mutation ERBB2 inhibitor Responsive LUAD Early trials
ERBB2 R678Q Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Early trials
ERBB2 R678Q Different Mutation ERBB2 mAb inhibitor Responsive LUAD Early trials
ERBB2 R678Q Different Mutation Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 R678Q Different Mutation Lapatinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 R678Q Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Early trials
ERBB2 R678Q Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Late trials
ERBB2 R678Q Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 R678Q Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive COREAD Late trials
ERBB2 R678Q Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive OV Early trials
ERBB2 R678Q Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB2 R678Q Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive COREAD Case report
ERBB2 R678Q Different Alteration Rociletinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 R678Q Different Alteration Osimertinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 R678Q Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 R678Q Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
ERBB2 R678Q Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BT Early trials
ERBB2 R678Q Different Alteration Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) Responsive BRCA Early trials
ERBB2 R678Q Different Alteration HER2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 R678Q Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 R678Q Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive ST Early trials
ERBB2 R678Q Different Alteration Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) Responsive BRCA Early trials
ERBB2 R678Q Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, GEJA FDA guidelines
ERBB2 R678Q Different Alteration ERBB2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 R678Q Different Alteration Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 R678Q Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive HNC Case report
ERBB2 R678Q Different Alteration Neratinib (ERBB2 inhibitor) Responsive BRCA Late trials
ERBB2 R678Q Different Alteration Trastuzumab (ERBB2 mAb inhibitor) No Responsive ED Early trials
ERBB2 R678Q Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive ED Pre-clinical
ERBB2 R678Q Different Alteration Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) Responsive ST Early trials
ERBB2 R678Q Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive ST Case report
ERBB2 R678Q Different Alteration EGFR inhibitor Resistant LUAD Pre-clinical
MET I565M Different Alteration Crizotinib (ALK inhibitor) Responsive G Case report
TP53 P278L Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 P278L Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 P278L Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 P278L Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 P278L Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 P278L Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 P278L Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P278L Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P278L Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 P278L Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 P278L Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 P278L Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P278L Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 P278L Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P278L Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NF1 W1048* Different Mutation Vemurafenib (BRAF inhibitor) Resistant CM Pre-clinical
NF1 W1048* Different Mutation Everolimus (MTOR inhibitor) Responsive HNC Case report
NF1 W1048* Complete Match Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 W1048* Complete Match Vinblastine (Chemotherapy) Responsive G Early trials
NF1 W1048* Complete Match KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 W1048* Complete Match Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 W1048* Complete Match Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 W1048* Complete Match Retinoic Acid Resistant NB Pre-clinical
NF1 W1048* Complete Match Everolimus (MTOR inhibitor) Responsive NF Late trials
NF1 W1048* Complete Match Trametinib (MEK inhibitor) Responsive G Case report
NF1 W1048* Complete Match Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 W1048* Complete Match Nilotinib (BCR-ABL inhibitor) Responsive MPN, PLEN Pre-clinical
NF1 W1048* Complete Match MEK inhibitor Responsive MPN Pre-clinical
NF1 W1048* Complete Match Everolimus (MTOR inhibitor) Responsive HNC, SG Case report
NF1 W1048* Complete Match Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 W1048* Complete Match PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 W1048* Complete Match MEK inhibitor Responsive LK, G Pre-clinical
NF1 W1048* Complete Match Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 W1048* Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 W1048* Complete Match AURK inhibitor Responsive MPN Pre-clinical
NF1 W1048* Complete Match MTOR inhibitor Responsive LK, G, MPN Pre-clinical
NF1 W1048* Complete Match Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 W1048* Complete Match Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) Responsive HC Case report
NF1 W1048* Complete Match Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 W1048* Complete Match Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 W1048* Complete Match PD1 Ab inhibitor Responsive CM Early trials
NF1 W1048* Complete Match Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 W1048* Complete Match Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 W1048* Complete Match Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 W1048* Complete Match BRD4 inhibitor Responsive MPN Pre-clinical
NF1 W1048* Complete Match Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 W1048* Complete Match Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 W1048* Complete Match MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 W1048* Complete Match Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 W1048* Complete Match Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 W1048* Complete Match Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 W1048* Different Alteration MTOR inhibitor Responsive MPN, G, LK Pre-clinical
NF1 W1048* Different Alteration PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 W1048* Different Alteration Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 W1048* Different Alteration Trametinib (MEK inhibitor) Responsive G Case report
NF1 W1048* Different Alteration BRD4 inhibitor Responsive MPN Pre-clinical
NF1 W1048* Different Alteration Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 W1048* Different Alteration Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 W1048* Different Alteration Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 W1048* Different Alteration MEK inhibitor Responsive G, LK Pre-clinical
NF1 W1048* Different Alteration Vinblastine (Chemotherapy) Responsive G Early trials
NF1 W1048* Different Alteration Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 W1048* Different Alteration Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 W1048* Different Alteration Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 W1048* Different Alteration MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 W1048* Different Alteration Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 W1048* Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 W1048* Different Alteration Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 W1048* Different Alteration Everolimus (MTOR inhibitor) Responsive SG, HNC Case report
NF1 W1048* Different Alteration Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 W1048* Different Alteration Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 W1048* Different Alteration Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 W1048* Different Alteration Retinoic Acid Resistant NB Pre-clinical
NF1 W1048* Different Alteration Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 W1048* Different Alteration Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 W1048* Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive PLEN, MPN Pre-clinical
NF1 W1048* Different Alteration Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 W1048* Different Alteration Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 W1048* Different Alteration AURK inhibitor Responsive MPN Pre-clinical
NF1 W1048* Different Alteration Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 W1048* Different Alteration PD1 Ab inhibitor Responsive CM Early trials
NF1 W1048* Different Alteration MEK inhibitor Responsive MPN Pre-clinical
NF1 W1048* Different Alteration KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 Q554* Different Mutation Vemurafenib (BRAF inhibitor) Resistant CM Pre-clinical
NF1 Q554* Different Mutation Everolimus (MTOR inhibitor) Responsive HNC Case report
NF1 Q554* Complete Match Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 Q554* Complete Match Vinblastine (Chemotherapy) Responsive G Early trials
NF1 Q554* Complete Match KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 Q554* Complete Match Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 Q554* Complete Match Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 Q554* Complete Match Retinoic Acid Resistant NB Pre-clinical
NF1 Q554* Complete Match Everolimus (MTOR inhibitor) Responsive NF Late trials
NF1 Q554* Complete Match Trametinib (MEK inhibitor) Responsive G Case report
NF1 Q554* Complete Match Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 Q554* Complete Match Nilotinib (BCR-ABL inhibitor) Responsive MPN, PLEN Pre-clinical
NF1 Q554* Complete Match MEK inhibitor Responsive MPN Pre-clinical
NF1 Q554* Complete Match Everolimus (MTOR inhibitor) Responsive HNC, SG Case report
NF1 Q554* Complete Match Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 Q554* Complete Match PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 Q554* Complete Match MEK inhibitor Responsive LK, G Pre-clinical
NF1 Q554* Complete Match Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 Q554* Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 Q554* Complete Match AURK inhibitor Responsive MPN Pre-clinical
NF1 Q554* Complete Match MTOR inhibitor Responsive LK, G, MPN Pre-clinical
NF1 Q554* Complete Match Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 Q554* Complete Match Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) Responsive HC Case report
NF1 Q554* Complete Match Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 Q554* Complete Match Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 Q554* Complete Match PD1 Ab inhibitor Responsive CM Early trials
NF1 Q554* Complete Match Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 Q554* Complete Match Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 Q554* Complete Match Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 Q554* Complete Match BRD4 inhibitor Responsive MPN Pre-clinical
NF1 Q554* Complete Match Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 Q554* Complete Match Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 Q554* Complete Match MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 Q554* Complete Match Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 Q554* Complete Match Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 Q554* Complete Match Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 Q554* Different Alteration MTOR inhibitor Responsive MPN, G, LK Pre-clinical
NF1 Q554* Different Alteration PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 Q554* Different Alteration Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 Q554* Different Alteration Trametinib (MEK inhibitor) Responsive G Case report
NF1 Q554* Different Alteration BRD4 inhibitor Responsive MPN Pre-clinical
NF1 Q554* Different Alteration Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 Q554* Different Alteration Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 Q554* Different Alteration Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 Q554* Different Alteration MEK inhibitor Responsive G, LK Pre-clinical
NF1 Q554* Different Alteration Vinblastine (Chemotherapy) Responsive G Early trials
NF1 Q554* Different Alteration Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 Q554* Different Alteration Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 Q554* Different Alteration Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 Q554* Different Alteration MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 Q554* Different Alteration Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 Q554* Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 Q554* Different Alteration Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 Q554* Different Alteration Everolimus (MTOR inhibitor) Responsive SG, HNC Case report
NF1 Q554* Different Alteration Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 Q554* Different Alteration Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 Q554* Different Alteration Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 Q554* Different Alteration Retinoic Acid Resistant NB Pre-clinical
NF1 Q554* Different Alteration Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 Q554* Different Alteration Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 Q554* Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive PLEN, MPN Pre-clinical
NF1 Q554* Different Alteration Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 Q554* Different Alteration Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 Q554* Different Alteration AURK inhibitor Responsive MPN Pre-clinical
NF1 Q554* Different Alteration Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 Q554* Different Alteration PD1 Ab inhibitor Responsive CM Early trials
NF1 Q554* Different Alteration MEK inhibitor Responsive MPN Pre-clinical
NF1 Q554* Different Alteration KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
TP53 Y163C Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Y163C Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Y163C Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Y163C Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Y163C Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Y163C Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Y163C Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y163C Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y163C Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Y163C Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Y163C Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Y163C Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y163C Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Y163C Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y163C Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 I255S Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 I255S Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 I255S Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 I255S Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 I255S Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 I255S Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 I255S Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 I255S Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 I255S Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 I255S Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 I255S Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 I255S Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 I255S Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 I255S Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 I255S Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
CDH1 Y835* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
TP53 E221* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 E221* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 E221* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 E221* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 E221* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 E221* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E221* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E221* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E221* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 E221* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 E221* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 E221* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E221* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 E221* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E221* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C135R Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C135R Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C135R Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C135R Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C135R Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C135R Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C135R Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C135R Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C135R Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C135R Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C135R Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C135R Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C135R Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C135R Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C135R Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ERBB4 P920R Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
NOTCH1 T887I Different Alteration Gamma secretase inhibitor Responsive ALL Pre-clinical
NOTCH1 T887I Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
ARID1A splice_donor_variant Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A splice_donor_variant Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A splice_donor_variant Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A splice_donor_variant Complete Match ATR inhibitor Responsive CANCER Pre-clinical
TP53 I195T Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 I195T Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 I195T Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 I195T Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 I195T Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 I195T Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 I195T Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 I195T Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 I195T Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 I195T Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 I195T Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 I195T Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 I195T Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 I195T Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 I195T Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NPM1 splice_acceptor_variant Complete Match Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
NPM1 splice_acceptor_variant Complete Match DOT1L inhibitor;MLL1 inhibitor Responsive AML Pre-clinical
ATR splice_acceptor_variant Complete Match Temozolomide (Chemotherapy) Responsive G Pre-clinical
ATR splice_acceptor_variant Complete Match Olaparib (PARP inhibitor) Responsive CANCER, OV Pre-clinical
ATR splice_acceptor_variant Different Alteration Olaparib (PARP inhibitor) Responsive OV, CANCER Pre-clinical
KMT2A P1367P Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A P1367P Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A P1367P Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A P1367P Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A P1367P Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A P1367P Different Alteration DOT1L inhibitor Responsive AML Early trials
TP53 K132E Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 K132E Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 K132E Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 K132E Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 K132E Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 K132E Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 K132E Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 K132E Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 K132E Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 K132E Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 K132E Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 K132E Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 K132E Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 K132E Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 K132E Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
EGFR D314G Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR D314G Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
RET R330Q Different Alteration Nintedanib (Pan-TK inhibitor) Responsive LUAD Case report
RET R330Q Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Early trials
RET R330Q Different Alteration RET inhibitor Responsive LUAD Pre-clinical
RET R330Q Different Alteration Vandetanib (Pan-TK inhibitor) Responsive LUAD Early trials
RET R330Q Different Alteration Sunitinib (Pan-TK inhibitor) Responsive LUAD Early trials
RET R330Q Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive THCA Pre-clinical
RET R330Q Different Alteration Vandetanib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET R330Q Different Alteration Sunitinib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET R330Q Different Alteration RET inhibitor Responsive TH Pre-clinical
PIK3CA N345T Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA N345T Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA N345T Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA N345T Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA N345T Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA N345T Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA N345T Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA N345T Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA N345T Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA N345T Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA N345T Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA N345T Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA N345T Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA N345T Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
ERBB2 S310F Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 S310F Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BRCA FDA guidelines
ERBB2 S310F Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, BRCA, GEJA FDA guidelines
ERBB2 S310F Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 S310F Different Alteration MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) Responsive SOLID Early trials
ERBB2 S310F Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 S310F Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 S310F Complete Match Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER, BRCA Pre-clinical
ERBB2 S310F Complete Match Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 S310F Different Mutation Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 S310F Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Case report
ERBB2 S310F Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA, LUAD Case report
ERBB2 S310F Complete Match Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive L Early trials
ERBB2 S310F Different Mutation Neratinib (ERBB2 inhibitor) Resistant BRCA Case report
ERBB2 S310F Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Pre-clinical
ERBB2 S310F Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Case report
ERBB2 S310F Different Mutation Lapatinib (ERBB2 inhibitor) Resistant BRCA Pre-clinical
ERBB2 S310F Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB2 S310F Complete Match Temsirolimus (MTOR inhibitor) Responsive LUAD Early trials
ERBB2 S310F Complete Match Dacomitinib (Pan ERBB inhibitor) Responsive NSCLC Early trials
ERBB2 S310F Complete Match Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 S310F Different Mutation ERBB2 inhibitor Responsive LUAD Early trials
ERBB2 S310F Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Early trials
ERBB2 S310F Different Mutation ERBB2 mAb inhibitor Responsive LUAD Early trials
ERBB2 S310F Different Mutation Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 S310F Different Mutation Lapatinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 S310F Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Early trials
ERBB2 S310F Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Late trials
ERBB2 S310F Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 S310F Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive COREAD Late trials
ERBB2 S310F Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive OV Early trials
ERBB2 S310F Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB2 S310F Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive COREAD Case report
ERBB2 S310F Different Alteration Rociletinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 S310F Different Alteration Osimertinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 S310F Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 S310F Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
ERBB2 S310F Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BT Early trials
ERBB2 S310F Different Alteration Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) Responsive BRCA Early trials
ERBB2 S310F Different Alteration HER2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 S310F Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 S310F Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive ST Early trials
ERBB2 S310F Different Alteration Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) Responsive BRCA Early trials
ERBB2 S310F Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, GEJA FDA guidelines
ERBB2 S310F Different Alteration ERBB2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 S310F Different Alteration Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 S310F Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive HNC Case report
ERBB2 S310F Different Alteration Neratinib (ERBB2 inhibitor) Responsive BRCA Late trials
ERBB2 S310F Different Alteration Trastuzumab (ERBB2 mAb inhibitor) No Responsive ED Early trials
ERBB2 S310F Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive ED Pre-clinical
ERBB2 S310F Different Alteration Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) Responsive ST Early trials
ERBB2 S310F Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive ST Case report
ERBB2 S310F Different Alteration EGFR inhibitor Resistant LUAD Pre-clinical
TP53 C135F Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C135F Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C135F Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C135F Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C135F Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C135F Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C135F Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C135F Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C135F Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C135F Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C135F Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C135F Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C135F Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C135F Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C135F Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ERBB3 G284R Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive CANCER Pre-clinical
ERBB3 G284R Complete Match Lapatinib (ERBB2 inhibitor) Responsive CANCER Pre-clinical
ERBB3 G284R Complete Match Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB3 G284R Complete Match Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB3 G284R Complete Match Pertuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB3 G284R Complete Match ERBB3 mAb inhibitor Responsive CANCER Pre-clinical
ERBB3 G284R Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
STAG2 splice_acceptor_variant Complete Match PARP inhibitor Responsive G Pre-clinical
BRCA1 E720* Complete Match Chemotherapy (PARP inhibitor;Chemotherapy) Responsive OV Early trials
BRCA1 E720* Complete Match PARP inhibitor Responsive BRCA Early trials
BRCA1 E720* Complete Match PARP inhibitor;Chemotherapy Responsive OV Early trials
BRCA1 E720* Complete Match Rucaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 E720* Complete Match Platinum Agent (Chemotherapy) Responsive BRCA Early trials
BRCA1 E720* Complete Match WEE1 inhibitor Responsive CANCER Case report
BRCA1 E720* Complete Match Platinum Agent (Chemotherapy) Responsive OV Late trials
BRCA1 E720* Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
BRCA1 E720* Complete Match Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) Responsive BRCA Early trials
BRCA1 E720* Complete Match PARP inhibitor Responsive PA Case report
BRCA1 E720* Complete Match Olaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 E720* Different Alteration PARP inhibitor Responsive OV Pre-clinical
TP53 R280S Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R280S Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R280S Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R280S Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R280S Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R280S Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R280S Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R280S Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R280S Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R280S Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R280S Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R280S Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R280S Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R280S Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R280S Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 splice_acceptor_variant Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 splice_acceptor_variant Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 splice_acceptor_variant Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 splice_acceptor_variant Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 splice_acceptor_variant Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 splice_acceptor_variant Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 splice_acceptor_variant Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 splice_acceptor_variant Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 splice_acceptor_variant Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 splice_acceptor_variant Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 splice_acceptor_variant Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 splice_acceptor_variant Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 splice_acceptor_variant Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 splice_acceptor_variant Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 splice_acceptor_variant Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 T155P Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 T155P Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 T155P Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 T155P Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 T155P Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 T155P Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 T155P Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 T155P Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 T155P Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 T155P Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 T155P Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 T155P Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 T155P Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 T155P Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 T155P Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
RET V778I Different Alteration Nintedanib (Pan-TK inhibitor) Responsive LUAD Case report
RET V778I Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Early trials
RET V778I Different Alteration RET inhibitor Responsive LUAD Pre-clinical
RET V778I Different Alteration Vandetanib (Pan-TK inhibitor) Responsive LUAD Early trials
RET V778I Different Alteration Sunitinib (Pan-TK inhibitor) Responsive LUAD Early trials
RET V778I Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive THCA Pre-clinical
RET V778I Different Alteration Vandetanib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET V778I Different Alteration Sunitinib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET V778I Different Alteration RET inhibitor Responsive TH Pre-clinical
PTEN I135K Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN I135K Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN I135K Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN I135K Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN I135K Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN I135K Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN I135K Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN I135K Complete Match PARP inhibitor Responsive ED Case report
PTEN I135K Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN I135K Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN I135K Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN I135K Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN I135K Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN I135K Complete Match AKT inhibitor Responsive PA Case report
PTEN I135K Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN I135K Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN I135K Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN I135K Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN I135K Different Alteration PARP inhibitor Responsive ED Case report
PTEN I135K Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN I135K Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN I135K Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN I135K Different Alteration AKT inhibitor Responsive PA Case report
PTEN I135K Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN I135K Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
TP53 Y220H Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Y220H Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Y220H Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Y220H Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Y220H Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Y220H Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Y220H Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y220H Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y220H Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Y220H Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Y220H Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Y220H Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y220H Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Y220H Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y220H Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C238Y Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C238Y Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C238Y Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C238Y Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C238Y Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C238Y Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C238Y Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C238Y Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C238Y Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C238Y Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C238Y Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C238Y Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C238Y Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C238Y Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C238Y Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ERBB2 G309A Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 G309A Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BRCA FDA guidelines
ERBB2 G309A Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, BRCA, GEJA FDA guidelines
ERBB2 G309A Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 G309A Different Alteration MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) Responsive SOLID Early trials
ERBB2 G309A Complete Match Lapatinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 G309A Complete Match Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 G309A Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER, BRCA Pre-clinical
ERBB2 G309A Different Mutation Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 G309A Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Case report
ERBB2 G309A Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA, LUAD Case report
ERBB2 G309A Different Mutation Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive L Early trials
ERBB2 G309A Different Mutation Neratinib (ERBB2 inhibitor) Resistant BRCA Case report
ERBB2 G309A Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Pre-clinical
ERBB2 G309A Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Case report
ERBB2 G309A Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 G309A Different Mutation Lapatinib (ERBB2 inhibitor) Resistant BRCA Pre-clinical
ERBB2 G309A Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB2 G309A Complete Match Temsirolimus (MTOR inhibitor) Responsive LUAD Early trials
ERBB2 G309A Complete Match Dacomitinib (Pan ERBB inhibitor) Responsive NSCLC Early trials
ERBB2 G309A Complete Match Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 G309A Different Mutation ERBB2 inhibitor Responsive LUAD Early trials
ERBB2 G309A Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Early trials
ERBB2 G309A Different Mutation ERBB2 mAb inhibitor Responsive LUAD Early trials
ERBB2 G309A Different Mutation Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 G309A Different Mutation Lapatinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 G309A Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Early trials
ERBB2 G309A Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Late trials
ERBB2 G309A Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 G309A Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive COREAD Late trials
ERBB2 G309A Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive OV Early trials
ERBB2 G309A Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB2 G309A Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive COREAD Case report
ERBB2 G309A Different Alteration Rociletinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 G309A Different Alteration Osimertinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 G309A Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 G309A Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
ERBB2 G309A Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BT Early trials
ERBB2 G309A Different Alteration Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) Responsive BRCA Early trials
ERBB2 G309A Different Alteration HER2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 G309A Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 G309A Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive ST Early trials
ERBB2 G309A Different Alteration Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) Responsive BRCA Early trials
ERBB2 G309A Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, GEJA FDA guidelines
ERBB2 G309A Different Alteration ERBB2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 G309A Different Alteration Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 G309A Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive HNC Case report
ERBB2 G309A Different Alteration Neratinib (ERBB2 inhibitor) Responsive BRCA Late trials
ERBB2 G309A Different Alteration Trastuzumab (ERBB2 mAb inhibitor) No Responsive ED Early trials
ERBB2 G309A Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive ED Pre-clinical
ERBB2 G309A Different Alteration Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) Responsive ST Early trials
ERBB2 G309A Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive ST Case report
ERBB2 G309A Different Alteration EGFR inhibitor Resistant LUAD Pre-clinical
TSC2 R1459* Different Mutation Temsirolimus (MTOR inhibitor) Responsive ED Case report
TSC2 R1459* Complete Match Everolimus (MTOR inhibitor) Responsive RA, GCA FDA guidelines
TSC2 R1459* Complete Match SRC inhibitor Responsive LAM Pre-clinical
TSC2 R1459* Complete Match Everolimus (MTOR inhibitor) Responsive BLCA Early trials
TSC2 R1459* Complete Match MTOR inhibitor Responsive RA Early trials
TSC2 R1459* Different Mutation Everolimus (MTOR inhibitor) Responsive THCA Case report
TSC2 R1459* Different Alteration SRC inhibitor Responsive LAM Pre-clinical
TP53 C176F Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C176F Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C176F Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C176F Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C176F Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C176F Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C176F Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C176F Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C176F Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C176F Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C176F Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C176F Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C176F Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C176F Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C176F Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NOTCH2 R1630G Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
PTEN R130Q Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN R130Q Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN R130Q Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN R130Q Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN R130Q Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN R130Q Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN R130Q Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN R130Q Complete Match PARP inhibitor Responsive ED Case report
PTEN R130Q Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN R130Q Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN R130Q Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN R130Q Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN R130Q Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN R130Q Complete Match AKT inhibitor Responsive PA Case report
PTEN R130Q Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN R130Q Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN R130Q Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN R130Q Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN R130Q Different Alteration PARP inhibitor Responsive ED Case report
PTEN R130Q Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN R130Q Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN R130Q Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN R130Q Different Alteration AKT inhibitor Responsive PA Case report
PTEN R130Q Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN R130Q Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
NOTCH2 S1388T Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
TP53 M237I Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 M237I Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 M237I Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 M237I Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 M237I Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 M237I Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 M237I Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 M237I Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 M237I Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 M237I Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 M237I Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 M237I Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 M237I Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 M237I Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 M237I Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 splice_donor_variant Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 splice_donor_variant Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 splice_donor_variant Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 splice_donor_variant Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 splice_donor_variant Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 splice_donor_variant Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 splice_donor_variant Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 splice_donor_variant Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 splice_donor_variant Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 splice_donor_variant Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 splice_donor_variant Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 splice_donor_variant Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 splice_donor_variant Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 splice_donor_variant Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 splice_donor_variant Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA E545K), PIK3CA MUT (E453K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E545K), PIK3CA MUT (E453K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E545K), PIK3CA MUT (E453K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E545K), PIK3CA MUT (E453K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E545K), PIK3CA MUT (E453K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E545K), PIK3CA MUT (E453K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E545K), PIK3CA MUT (E453K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E545K), PIK3CA MUT (E453K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E545K), PIK3CA MUT (E453K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E545K), PIK3CA MUT (E453K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E545K), PIK3CA MUT (E453K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E545K), PIK3CA MUT (E453K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E545K), PIK3CA MUT (E453K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E545K), PIK3CA MUT (E453K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
TP53 H179R Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 H179R Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 H179R Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 H179R Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 H179R Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 H179R Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 H179R Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H179R Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H179R Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 H179R Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 H179R Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 H179R Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H179R Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 H179R Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H179R Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ESR1 K472K Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
TP53 Q52* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Q52* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Q52* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Q52* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Q52* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Q52* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Q52* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q52* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q52* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Q52* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Q52* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Q52* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q52* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Q52* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q52* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
RET L963V Different Alteration Nintedanib (Pan-TK inhibitor) Responsive LUAD Case report
RET L963V Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Early trials
RET L963V Different Alteration RET inhibitor Responsive LUAD Pre-clinical
RET L963V Different Alteration Vandetanib (Pan-TK inhibitor) Responsive LUAD Early trials
RET L963V Different Alteration Sunitinib (Pan-TK inhibitor) Responsive LUAD Early trials
RET L963V Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive THCA Pre-clinical
RET L963V Different Alteration Vandetanib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET L963V Different Alteration Sunitinib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET L963V Different Alteration RET inhibitor Responsive TH Pre-clinical
EGFR A147T Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR A147T Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
TP53 P250L Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 P250L Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 P250L Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 P250L Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 P250L Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 P250L Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 P250L Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P250L Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P250L Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 P250L Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 P250L Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 P250L Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P250L Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 P250L Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P250L Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ESR1 P336P Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
TP53 G279E Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 G279E Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 G279E Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 G279E Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 G279E Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 G279E Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 G279E Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G279E Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G279E Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 G279E Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 G279E Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 G279E Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G279E Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 G279E Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G279E Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ROS1 splice_donor_variant Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 splice_donor_variant Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 splice_donor_variant Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 splice_donor_variant Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 splice_donor_variant Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
MET G225D Different Alteration Crizotinib (ALK inhibitor) Responsive G Case report
PDGFRA intron_variant Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive MDPS, MDS, ECL, HES FDA guidelines
BRCA1 E272* Complete Match Chemotherapy (PARP inhibitor;Chemotherapy) Responsive OV Early trials
BRCA1 E272* Complete Match PARP inhibitor Responsive BRCA Early trials
BRCA1 E272* Complete Match PARP inhibitor;Chemotherapy Responsive OV Early trials
BRCA1 E272* Complete Match Rucaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 E272* Complete Match Platinum Agent (Chemotherapy) Responsive BRCA Early trials
BRCA1 E272* Complete Match WEE1 inhibitor Responsive CANCER Case report
BRCA1 E272* Complete Match Platinum Agent (Chemotherapy) Responsive OV Late trials
BRCA1 E272* Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
BRCA1 E272* Complete Match Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) Responsive BRCA Early trials
BRCA1 E272* Complete Match PARP inhibitor Responsive PA Case report
BRCA1 E272* Complete Match Olaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 E272* Different Alteration PARP inhibitor Responsive OV Pre-clinical
BRD4 K546N Different Alteration BET inhibitor Responsive NMC Case report
TP53 S215I Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 S215I Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 S215I Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 S215I Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 S215I Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 S215I Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 S215I Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 S215I Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 S215I Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 S215I Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 S215I Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 S215I Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 S215I Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 S215I Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 S215I Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 G266E Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 G266E Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 G266E Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 G266E Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 G266E Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 G266E Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 G266E Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G266E Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G266E Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 G266E Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 G266E Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 G266E Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G266E Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 G266E Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G266E Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
BRD4 A264A Different Alteration BET inhibitor Responsive NMC Case report
ABL1 Y440H Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
ABL1 Y440H Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
ABL1 Y440H Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
ABL1 Y440H Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
ABL1 Y440H Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
ABL1 Y440H Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
EGFR E282K Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR E282K Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
AKT1 E17K Complete Match BRAF inhibitor Resistant CM Case report
AKT1 E17K Complete Match allosteric AKT inhibitor Responsive CANCER Early trials
AKT1 E17K Complete Match non-allosteric AKT inhibitor Responsive CANCER Early trials
AKT1 E17K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
AKT1 E17K Complete Match Temsirolimus (MTOR inhibitor) Responsive ED Early trials
AKT1 E17K Complete Match AKT inhibitor Responsive CANCER Pre-clinical
AKT1 E17K Different Mutation Everolimus (MTOR inhibitor) Responsive FH Case report
ERBB2 V842I Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 V842I Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BRCA FDA guidelines
ERBB2 V842I Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, BRCA, GEJA FDA guidelines
ERBB2 V842I Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 V842I Different Alteration MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) Responsive SOLID Early trials
ERBB2 V842I Complete Match Lapatinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 V842I Complete Match Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 V842I Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER, BRCA Pre-clinical
ERBB2 V842I Complete Match Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 V842I Different Mutation Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 V842I Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Case report
ERBB2 V842I Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA, LUAD Case report
ERBB2 V842I Different Mutation Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive L Early trials
ERBB2 V842I Different Mutation Neratinib (ERBB2 inhibitor) Resistant BRCA Case report
ERBB2 V842I Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Pre-clinical
ERBB2 V842I Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Case report
ERBB2 V842I Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 V842I Different Mutation Lapatinib (ERBB2 inhibitor) Resistant BRCA Pre-clinical
ERBB2 V842I Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB2 V842I Complete Match Temsirolimus (MTOR inhibitor) Responsive LUAD Early trials
ERBB2 V842I Complete Match Dacomitinib (Pan ERBB inhibitor) Responsive NSCLC Early trials
ERBB2 V842I Complete Match Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 V842I Different Mutation ERBB2 inhibitor Responsive LUAD Early trials
ERBB2 V842I Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Early trials
ERBB2 V842I Different Mutation ERBB2 mAb inhibitor Responsive LUAD Early trials
ERBB2 V842I Different Mutation Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 V842I Different Mutation Lapatinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 V842I Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Early trials
ERBB2 V842I Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Late trials
ERBB2 V842I Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 V842I Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive COREAD Late trials
ERBB2 V842I Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive OV Early trials
ERBB2 V842I Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB2 V842I Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive COREAD Case report
ERBB2 V842I Different Alteration Rociletinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 V842I Different Alteration Osimertinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 V842I Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 V842I Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
ERBB2 V842I Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BT Early trials
ERBB2 V842I Different Alteration Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) Responsive BRCA Early trials
ERBB2 V842I Different Alteration HER2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 V842I Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 V842I Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive ST Early trials
ERBB2 V842I Different Alteration Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) Responsive BRCA Early trials
ERBB2 V842I Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, GEJA FDA guidelines
ERBB2 V842I Different Alteration ERBB2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 V842I Different Alteration Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 V842I Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive HNC Case report
ERBB2 V842I Different Alteration Neratinib (ERBB2 inhibitor) Responsive BRCA Late trials
ERBB2 V842I Different Alteration Trastuzumab (ERBB2 mAb inhibitor) No Responsive ED Early trials
ERBB2 V842I Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive ED Pre-clinical
ERBB2 V842I Different Alteration Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) Responsive ST Early trials
ERBB2 V842I Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive ST Case report
ERBB2 V842I Different Alteration EGFR inhibitor Resistant LUAD Pre-clinical
KMT2A Q1195* Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A Q1195* Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A Q1195* Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A Q1195* Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A Q1195* Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A Q1195* Different Alteration DOT1L inhibitor Responsive AML Early trials
TMPRSS2 P83P Different Alteration DNA-PKc inhibitor Responsive PRAD Pre-clinical
TMPRSS2 P83P Different Alteration PARP inhibitor Responsive PRAD Pre-clinical
JAK2 Y44* Different Alteration Ruxolitinib (JAK inhibitor) Responsive ALL Pre-clinical
ROS1 R1182S Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 R1182S Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 R1182S Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 R1182S Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 R1182S Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
FAT1 Q1722* Complete Match BET inhibitor Responsive HNSC Pre-clinical
BRCA2 splice_donor_variant Complete Match PD1 Ab inhibitor Responsive CM Case report
BRCA2 splice_donor_variant Complete Match Olaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA2 splice_donor_variant Complete Match Platinum Agent (Chemotherapy) Responsive OV Late trials
BRCA2 splice_donor_variant Complete Match Chemotherapy (PARP inhibitor;Chemotherapy) Responsive OV Early trials
BRCA2 splice_donor_variant Complete Match PARP inhibitor;Chemotherapy Responsive OV Early trials
BRCA2 splice_donor_variant Complete Match Platinum Agent (Chemotherapy) Responsive PA Case report
BRCA2 splice_donor_variant Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
BRCA2 splice_donor_variant Complete Match Rucaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA2 splice_donor_variant Complete Match PD1/PDL1 inhibitor Responsive UTH Early trials
BRCA2 splice_donor_variant Complete Match Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) Responsive BRCA Early trials
BRCA2 splice_donor_variant Complete Match Platinum Agent (Chemotherapy) Responsive BRCA Early trials
BRCA2 splice_donor_variant Complete Match PARP inhibitor Responsive BRCA Early trials
BRCA2 splice_donor_variant Different Alteration PD1/PDL1 inhibitor Responsive UTH Early trials
BRCA2 splice_donor_variant Different Alteration PARP inhibitor Responsive OV Pre-clinical
JAK2 Y132* Different Alteration Ruxolitinib (JAK inhibitor) Responsive ALL Pre-clinical
SETD2 S470* Complete Match WEE1 inhibitor Responsive CANCER Pre-clinical
SETD2 S470* Different Alteration WEE1 inhibitor Responsive CANCER Pre-clinical
PIK3CA H1047L), PIK3CA MUT (E726K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA H1047L), PIK3CA MUT (E726K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA H1047L), PIK3CA MUT (E726K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
ROS1 E596K Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 E596K Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 E596K Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 E596K Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 E596K Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
RB1 E864* Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 E864* Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 E864* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 E864* Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 E864* Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 E864* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 E864* Different Alteration HDAC inhibitor Responsive RB Pre-clinical
PIK3CA Q546K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA Q546K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA Q546K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA Q546K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA Q546K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA Q546K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA Q546K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA Q546K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA Q546K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA Q546K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA Q546K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA Q546K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA Q546K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA Q546K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
TP53 C141Y Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C141Y Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C141Y Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C141Y Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C141Y Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C141Y Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C141Y Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C141Y Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C141Y Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C141Y Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C141Y Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C141Y Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C141Y Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C141Y Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C141Y Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
FGFR3 H711H Different Alteration FGFR inhibitor Responsive BLCA Case report
FGFR3 H711H Different Alteration FGFR inhibitor Responsive G Early trials
FGFR3 H711H Different Alteration FGFR inhibitor Responsive NSCLC Pre-clinical
TP53 Q144* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Q144* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Q144* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Q144* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Q144* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Q144* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Q144* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q144* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q144* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Q144* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Q144* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Q144* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q144* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Q144* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q144* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
CDH1 Q641* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
PTEN Y46* Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN Y46* Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN Y46* Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN Y46* Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN Y46* Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN Y46* Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN Y46* Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN Y46* Complete Match PARP inhibitor Responsive ED Case report
PTEN Y46* Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN Y46* Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN Y46* Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN Y46* Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN Y46* Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN Y46* Complete Match AKT inhibitor Responsive PA Case report
PTEN Y46* Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN Y46* Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN Y46* Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN Y46* Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN Y46* Different Alteration PARP inhibitor Responsive ED Case report
PTEN Y46* Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN Y46* Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN Y46* Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN Y46* Different Alteration AKT inhibitor Responsive PA Case report
PTEN Y46* Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN Y46* Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
TP53 H193R Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 H193R Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 H193R Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 H193R Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 H193R Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 H193R Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 H193R Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H193R Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H193R Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 H193R Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 H193R Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 H193R Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H193R Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 H193R Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H193R Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NTRK3 splice_donor_variant Different Alteration IGF1R inhibitor Responsive BRCA Pre-clinical
NTRK3 splice_donor_variant Different Alteration PI3K pathway inhibitor Responsive BRCA Pre-clinical
NTRK3 splice_donor_variant Different Alteration Midostaurin (Pan-TK inhibitor) Responsive BRCA Pre-clinical
AKT3 A373G Different Alteration ATP competitive AKT inhibitor Responsive BRCA Pre-clinical
PML L726L Different Alteration Volasertib (PLK1 inhibitor) Responsive AML Early trials
PML L726L Different Alteration Tretinoin (Retinoid) Responsive APML FDA guidelines
PML L726L Different Alteration Tretinoin;Arsenic Trioxide (Retinoid;Chemotherapy) Responsive AML FDA guidelines
PIK3CA E726K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E726K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E726K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E726K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E726K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E726K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E726K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E726K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E726K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E726K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E726K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E726K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E726K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E726K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
FGFR2 V113A Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 V113A Different Alteration FGFR inhibitor Responsive BT Early trials
STAG2 Q167* Complete Match PARP inhibitor Responsive G Pre-clinical
KMT2A S3380L Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A S3380L Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A S3380L Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A S3380L Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A S3380L Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A S3380L Different Alteration DOT1L inhibitor Responsive AML Early trials
NOTCH1 F1259F Different Alteration Gamma secretase inhibitor Responsive ALL Pre-clinical
NOTCH1 F1259F Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
PDGFRA D985N Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive MDPS, MDS, ECL, HES FDA guidelines
ALK R1209P Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK R1209P Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK R1209P Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK R1209P Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK R1209P Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK R1209P Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK R1209P Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK R1209P Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK R1209P Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK R1209P Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK R1209P Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK R1209P Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK R1209P Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK R1209P Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK R1209P Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK R1209P Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK R1209P Different Alteration ALK inhibitor Responsive COREAD Case report
ALK R1209P Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK R1209P Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
NTRK1 S371F Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Case report
NTRK1 S371F Different Alteration Pan-TKR inhibitor Responsive CANCER Early trials
NTRK1 S371F Different Alteration Pan-TK inhibitor Responsive LUAD Pre-clinical
NTRK1 S371F Different Alteration Pan-TK inhibitor Responsive COREAD Case report
NOTCH2 A2331S Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
ESR1 L448L Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
EGFR D1051N), EGFR MUT* (intron_variant Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR D1051N), EGFR MUT* (intron_variant Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
ABL1 E588Q Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
ABL1 E588Q Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
ABL1 E588Q Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
ABL1 E588Q Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
ABL1 E588Q Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
ABL1 E588Q Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
ROS1 H189Y), ROS1 MUT* (3-UTRSNV Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 H189Y), ROS1 MUT* (3-UTRSNV Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 H189Y), ROS1 MUT* (3-UTRSNV Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 H189Y), ROS1 MUT* (3-UTRSNV Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 H189Y), ROS1 MUT* (3-UTRSNV Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
MET R992T), MET MUT* (L581L Different Alteration Crizotinib (ALK inhibitor) Responsive G Case report
BRAF D449N Different Alteration Sorafenib (Pan-TK inhibitor) Responsive CM, LUAD, PRAD Pre-clinical
BRAF D449N Different Alteration MEK inhibitor Responsive LUAD, CM, PRAD Pre-clinical
BRAF D449N Different Alteration Selumetinib (MEK inhibitor) Responsive OV Case report
BRAF D449N Different Alteration BRAF inhibitor;MEK inhibitor Responsive LUAD Case report
ERBB4 S184L), ERBB4 MUT* (E1144Q), ERBB4 MUT* (3-UTRSNV Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
SETD2 S791* Complete Match WEE1 inhibitor Responsive CANCER Pre-clinical
SETD2 S791* Different Alteration WEE1 inhibitor Responsive CANCER Pre-clinical
ERBB2 L755S Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 L755S Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BRCA FDA guidelines
ERBB2 L755S Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, BRCA, GEJA FDA guidelines
ERBB2 L755S Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 L755S Different Alteration MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) Responsive SOLID Early trials
ERBB2 L755S Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 L755S Complete Match Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 L755S Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER, BRCA Pre-clinical
ERBB2 L755S Complete Match Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 L755S Different Mutation Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 L755S Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Case report
ERBB2 L755S Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA, LUAD Case report
ERBB2 L755S Different Mutation Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive L Early trials
ERBB2 L755S Different Mutation Neratinib (ERBB2 inhibitor) Resistant BRCA Case report
ERBB2 L755S Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Pre-clinical
ERBB2 L755S Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Case report
ERBB2 L755S Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 L755S Different Mutation Lapatinib (ERBB2 inhibitor) Resistant BRCA Pre-clinical
ERBB2 L755S Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB2 L755S Complete Match Temsirolimus (MTOR inhibitor) Responsive LUAD Early trials
ERBB2 L755S Complete Match Dacomitinib (Pan ERBB inhibitor) Responsive NSCLC Early trials
ERBB2 L755S Complete Match Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 L755S Different Mutation ERBB2 inhibitor Responsive LUAD Early trials
ERBB2 L755S Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Early trials
ERBB2 L755S Different Mutation ERBB2 mAb inhibitor Responsive LUAD Early trials
ERBB2 L755S Different Mutation Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 L755S Different Mutation Lapatinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 L755S Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Early trials
ERBB2 L755S Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Late trials
ERBB2 L755S Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 L755S Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive COREAD Late trials
ERBB2 L755S Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive OV Early trials
ERBB2 L755S Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB2 L755S Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive COREAD Case report
ERBB2 L755S Different Alteration Rociletinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 L755S Different Alteration Osimertinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 L755S Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 L755S Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
ERBB2 L755S Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BT Early trials
ERBB2 L755S Different Alteration Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) Responsive BRCA Early trials
ERBB2 L755S Different Alteration HER2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 L755S Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 L755S Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive ST Early trials
ERBB2 L755S Different Alteration Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) Responsive BRCA Early trials
ERBB2 L755S Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, GEJA FDA guidelines
ERBB2 L755S Different Alteration ERBB2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 L755S Different Alteration Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 L755S Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive HNC Case report
ERBB2 L755S Different Alteration Neratinib (ERBB2 inhibitor) Responsive BRCA Late trials
ERBB2 L755S Different Alteration Trastuzumab (ERBB2 mAb inhibitor) No Responsive ED Early trials
ERBB2 L755S Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive ED Pre-clinical
ERBB2 L755S Different Alteration Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) Responsive ST Early trials
ERBB2 L755S Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive ST Case report
ERBB2 L755S Different Alteration EGFR inhibitor Resistant LUAD Pre-clinical
FGFR2 S588C Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 S588C Different Alteration FGFR inhibitor Responsive BT Early trials
TP53 M246I Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 M246I Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 M246I Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 M246I Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 M246I Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 M246I Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 M246I Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 M246I Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 M246I Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 M246I Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 M246I Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 M246I Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 M246I Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 M246I Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 M246I Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
GNAS R201C Complete Match JAK inhibitor Responsive CANCER Pre-clinical
KMT2D L2255* Complete Match Bicalutamide (AR inhibitor) Responsive LUSC Pre-clinical
TP53 D281Y Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 D281Y Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 D281Y Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 D281Y Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 D281Y Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 D281Y Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 D281Y Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 D281Y Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 D281Y Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 D281Y Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 D281Y Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 D281Y Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 D281Y Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 D281Y Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 D281Y Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
CDH1 Q503* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
NTRK1 G319D Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Case report
NTRK1 G319D Different Alteration Pan-TKR inhibitor Responsive CANCER Early trials
NTRK1 G319D Different Alteration Pan-TK inhibitor Responsive LUAD Pre-clinical
NTRK1 G319D Different Alteration Pan-TK inhibitor Responsive COREAD Case report
NOTCH2 T2159T Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
RAF1 V226D Different Alteration Sorafenib (Pan-TK inhibitor) Responsive PRAD Pre-clinical
RAF1 V226D Different Alteration Pan-RAF inhibitor Responsive PRAD Pre-clinical
RAF1 V226D Different Alteration U0126 (MEK inhibitor) Responsive PRAD Pre-clinical
ESR1 3-UTRSNV Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
SF3B1 E622Q Different Mutation Spliceosome inhibitor Responsive CANCER Pre-clinical
RB1 Y606* Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 Y606* Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 Y606* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 Y606* Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 Y606* Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 Y606* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 Y606* Different Alteration HDAC inhibitor Responsive RB Pre-clinical
ATM Q2800* Different Mutation AZD6738 (ATR inhibitor) Responsive BCL Early trials
ATM Q2800* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
ATM Q2800* Complete Match Olaparib (PARP inhibitor) Responsive ST, PRAD Early trials
ATM Q2800* Complete Match PARP inhibitor Responsive ST Early trials
ATM Q2800* Complete Match ATR inhibitor Responsive COREAD Case report
ATM Q2800* Complete Match DNA-PKc inhibitor Responsive LY Pre-clinical
ATM Q2800* Complete Match Temozolomide (Chemotherapy) Responsive G Pre-clinical
ATM Q2800* Complete Match PD1/PDL1 inhibitor Responsive UTH Early trials
ATM Q2800* Different Alteration PD1/PDL1 inhibitor Responsive UTH Early trials
ATM Q2800* Different Alteration DNA-PKc inhibitor Responsive LY Pre-clinical
ATM Q2800* Different Alteration PARP inhibitor Responsive ST Early trials
ATM Q2800* Different Alteration ATR inhibitor Responsive COREAD Case report
ATM Q2800* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
KMT2A P3959P Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A P3959P Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A P3959P Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A P3959P Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A P3959P Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A P3959P Different Alteration DOT1L inhibitor Responsive AML Early trials
CDH1 Q647* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
ERBB4 E1205K Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
PIK3CA E545A Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E545A Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E545A Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E545A Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E545A Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E545A Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E545A Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E545A Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E545A Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E545A Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E545A Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E545A Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E545A Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E545A Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
MET A932A Different Alteration Crizotinib (ALK inhibitor) Responsive G Case report
TP53 R342P Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R342P Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R342P Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R342P Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R342P Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R342P Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R342P Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R342P Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R342P Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R342P Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R342P Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R342P Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R342P Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R342P Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R342P Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
GATA3 splice_acceptor_variant Complete Match Aromatase ihibitor Responsive BRCA Pre-clinical
CDH1 R74* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
ALK N1544N Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK N1544N Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK N1544N Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK N1544N Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK N1544N Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK N1544N Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK N1544N Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK N1544N Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK N1544N Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK N1544N Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK N1544N Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK N1544N Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK N1544N Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK N1544N Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK N1544N Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK N1544N Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK N1544N Different Alteration ALK inhibitor Responsive COREAD Case report
ALK N1544N Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK N1544N Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
ALK G1121D Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK G1121D Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK G1121D Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK G1121D Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK G1121D Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK G1121D Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK G1121D Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK G1121D Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK G1121D Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK G1121D Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK G1121D Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK G1121D Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK G1121D Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK G1121D Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK G1121D Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK G1121D Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK G1121D Different Alteration ALK inhibitor Responsive COREAD Case report
ALK G1121D Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK G1121D Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
HIF1A R463* Different Alteration Sunitinib (Pan-TK inhibitor) Responsive R Pre-clinical
RB1 splice_donor_variant Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 splice_donor_variant Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 splice_donor_variant Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 splice_donor_variant Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 splice_donor_variant Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 splice_donor_variant Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 splice_donor_variant Different Alteration HDAC inhibitor Responsive RB Pre-clinical
ERCC6 R612* Complete Match Cisplatin (Chemotherapy) Responsive OV Pre-clinical
PTEN S59* Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN S59* Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN S59* Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN S59* Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN S59* Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN S59* Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN S59* Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN S59* Complete Match PARP inhibitor Responsive ED Case report
PTEN S59* Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN S59* Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN S59* Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN S59* Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN S59* Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN S59* Complete Match AKT inhibitor Responsive PA Case report
PTEN S59* Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN S59* Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN S59* Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN S59* Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN S59* Different Alteration PARP inhibitor Responsive ED Case report
PTEN S59* Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN S59* Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN S59* Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN S59* Different Alteration AKT inhibitor Responsive PA Case report
PTEN S59* Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN S59* Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
FGFR2 V635A Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 V635A Different Alteration FGFR inhibitor Responsive BT Early trials
KMT2A R3744Q), MLL MUT* (R652* Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A R3744Q), MLL MUT* (R652* Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A R3744Q), MLL MUT* (R652* Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A R3744Q), MLL MUT* (R652* Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A R3744Q), MLL MUT* (R652* Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A R3744Q), MLL MUT* (R652* Different Alteration DOT1L inhibitor Responsive AML Early trials
SMARCA4 E1426* Complete Match EZH2 inhibitor Responsive OVRT Case report
SMARCA4 E1426* Complete Match AURKA inhibitor Responsive NSCLC Pre-clinical
SMARCA4 E1426* Complete Match EZH2 inhibitor Responsive OV Case report
SMARCA4 E1426* Different Alteration EZH2 inhibitor Responsive OVRT Case report
SMARCA4 E1426* Different Alteration EZH2 inhibitor Responsive OV Case report
NF1 E1734* Different Mutation Vemurafenib (BRAF inhibitor) Resistant CM Pre-clinical
NF1 E1734* Different Mutation Everolimus (MTOR inhibitor) Responsive HNC Case report
NF1 E1734* Complete Match Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 E1734* Complete Match Vinblastine (Chemotherapy) Responsive G Early trials
NF1 E1734* Complete Match KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 E1734* Complete Match Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 E1734* Complete Match Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 E1734* Complete Match Retinoic Acid Resistant NB Pre-clinical
NF1 E1734* Complete Match Everolimus (MTOR inhibitor) Responsive NF Late trials
NF1 E1734* Complete Match Trametinib (MEK inhibitor) Responsive G Case report
NF1 E1734* Complete Match Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 E1734* Complete Match Nilotinib (BCR-ABL inhibitor) Responsive MPN, PLEN Pre-clinical
NF1 E1734* Complete Match MEK inhibitor Responsive MPN Pre-clinical
NF1 E1734* Complete Match Everolimus (MTOR inhibitor) Responsive HNC, SG Case report
NF1 E1734* Complete Match Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 E1734* Complete Match PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 E1734* Complete Match MEK inhibitor Responsive LK, G Pre-clinical
NF1 E1734* Complete Match Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 E1734* Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 E1734* Complete Match AURK inhibitor Responsive MPN Pre-clinical
NF1 E1734* Complete Match MTOR inhibitor Responsive LK, G, MPN Pre-clinical
NF1 E1734* Complete Match Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 E1734* Complete Match Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) Responsive HC Case report
NF1 E1734* Complete Match Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 E1734* Complete Match Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 E1734* Complete Match PD1 Ab inhibitor Responsive CM Early trials
NF1 E1734* Complete Match Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 E1734* Complete Match Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 E1734* Complete Match Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 E1734* Complete Match BRD4 inhibitor Responsive MPN Pre-clinical
NF1 E1734* Complete Match Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 E1734* Complete Match Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 E1734* Complete Match MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 E1734* Complete Match Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 E1734* Complete Match Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 E1734* Complete Match Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 E1734* Different Alteration MTOR inhibitor Responsive MPN, G, LK Pre-clinical
NF1 E1734* Different Alteration PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 E1734* Different Alteration Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 E1734* Different Alteration Trametinib (MEK inhibitor) Responsive G Case report
NF1 E1734* Different Alteration BRD4 inhibitor Responsive MPN Pre-clinical
NF1 E1734* Different Alteration Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 E1734* Different Alteration Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 E1734* Different Alteration Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 E1734* Different Alteration MEK inhibitor Responsive G, LK Pre-clinical
NF1 E1734* Different Alteration Vinblastine (Chemotherapy) Responsive G Early trials
NF1 E1734* Different Alteration Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 E1734* Different Alteration Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 E1734* Different Alteration Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 E1734* Different Alteration MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 E1734* Different Alteration Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 E1734* Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 E1734* Different Alteration Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 E1734* Different Alteration Everolimus (MTOR inhibitor) Responsive SG, HNC Case report
NF1 E1734* Different Alteration Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 E1734* Different Alteration Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 E1734* Different Alteration Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 E1734* Different Alteration Retinoic Acid Resistant NB Pre-clinical
NF1 E1734* Different Alteration Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 E1734* Different Alteration Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 E1734* Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive PLEN, MPN Pre-clinical
NF1 E1734* Different Alteration Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 E1734* Different Alteration Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 E1734* Different Alteration AURK inhibitor Responsive MPN Pre-clinical
NF1 E1734* Different Alteration Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 E1734* Different Alteration PD1 Ab inhibitor Responsive CM Early trials
NF1 E1734* Different Alteration MEK inhibitor Responsive MPN Pre-clinical
NF1 E1734* Different Alteration KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
BRD4 P723P Different Alteration BET inhibitor Responsive NMC Case report
ESR1 A593D Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
ROS1 K1661Q Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 K1661Q Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 K1661Q Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 K1661Q Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 K1661Q Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
NRG1 R155I Different Alteration Lapatinib (ERBB2 inhibitor) Responsive LUAD Pre-clinical
NRG1 R155I Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Case report
APC E109*), APC MUT (S2223* Complete Match Tankyrase inhibitor Responsive COREAD Pre-clinical
PIK3R1 R557*), PIK3R1 MUT (R348* Complete Match AKT inhibitor Responsive G Pre-clinical
PIK3R1 R557*), PIK3R1 MUT (R348* Complete Match PI3K pathway inhibitor Responsive ED Case report
PDGFRA I139I Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive MDPS, MDS, ECL, HES FDA guidelines
ERBB4 F401L Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
ATR R1368* Complete Match Temozolomide (Chemotherapy) Responsive G Pre-clinical
ATR R1368* Complete Match Olaparib (PARP inhibitor) Responsive CANCER, OV Pre-clinical
ATR R1368* Different Alteration Olaparib (PARP inhibitor) Responsive OV, CANCER Pre-clinical
PIK3CA Y1021C), PIK3CA MUT (R349* Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA Y1021C), PIK3CA MUT (R349* Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA Y1021C), PIK3CA MUT (R349* Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
RAF1 S605F Different Alteration Sorafenib (Pan-TK inhibitor) Responsive PRAD Pre-clinical
RAF1 S605F Different Alteration Pan-RAF inhibitor Responsive PRAD Pre-clinical
RAF1 S605F Different Alteration U0126 (MEK inhibitor) Responsive PRAD Pre-clinical
NTRK3 T369N Different Alteration IGF1R inhibitor Responsive BRCA Pre-clinical
NTRK3 T369N Different Alteration PI3K pathway inhibitor Responsive BRCA Pre-clinical
NTRK3 T369N Different Alteration Midostaurin (Pan-TK inhibitor) Responsive BRCA Pre-clinical
TP53 L194R Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 L194R Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 L194R Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 L194R Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 L194R Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 L194R Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 L194R Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L194R Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L194R Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 L194R Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 L194R Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 L194R Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L194R Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 L194R Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L194R Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NF1 splice_donor_variant Different Mutation Vemurafenib (BRAF inhibitor) Resistant CM Pre-clinical
NF1 splice_donor_variant Different Mutation Everolimus (MTOR inhibitor) Responsive HNC Case report
NF1 splice_donor_variant Complete Match Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 splice_donor_variant Complete Match Vinblastine (Chemotherapy) Responsive G Early trials
NF1 splice_donor_variant Complete Match KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 splice_donor_variant Complete Match Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 splice_donor_variant Complete Match Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 splice_donor_variant Complete Match Retinoic Acid Resistant NB Pre-clinical
NF1 splice_donor_variant Complete Match Everolimus (MTOR inhibitor) Responsive NF Late trials
NF1 splice_donor_variant Complete Match Trametinib (MEK inhibitor) Responsive G Case report
NF1 splice_donor_variant Complete Match Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 splice_donor_variant Complete Match Nilotinib (BCR-ABL inhibitor) Responsive MPN, PLEN Pre-clinical
NF1 splice_donor_variant Complete Match MEK inhibitor Responsive MPN Pre-clinical
NF1 splice_donor_variant Complete Match Everolimus (MTOR inhibitor) Responsive HNC, SG Case report
NF1 splice_donor_variant Complete Match Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 splice_donor_variant Complete Match PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 splice_donor_variant Complete Match MEK inhibitor Responsive LK, G Pre-clinical
NF1 splice_donor_variant Complete Match Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 splice_donor_variant Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 splice_donor_variant Complete Match AURK inhibitor Responsive MPN Pre-clinical
NF1 splice_donor_variant Complete Match MTOR inhibitor Responsive LK, G, MPN Pre-clinical
NF1 splice_donor_variant Complete Match Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 splice_donor_variant Complete Match Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) Responsive HC Case report
NF1 splice_donor_variant Complete Match Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 splice_donor_variant Complete Match Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 splice_donor_variant Complete Match PD1 Ab inhibitor Responsive CM Early trials
NF1 splice_donor_variant Complete Match Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 splice_donor_variant Complete Match Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 splice_donor_variant Complete Match Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 splice_donor_variant Complete Match BRD4 inhibitor Responsive MPN Pre-clinical
NF1 splice_donor_variant Complete Match Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 splice_donor_variant Complete Match Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 splice_donor_variant Complete Match MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 splice_donor_variant Complete Match Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 splice_donor_variant Complete Match Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 splice_donor_variant Complete Match Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 splice_donor_variant Different Alteration MTOR inhibitor Responsive MPN, G, LK Pre-clinical
NF1 splice_donor_variant Different Alteration PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 splice_donor_variant Different Alteration Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 splice_donor_variant Different Alteration Trametinib (MEK inhibitor) Responsive G Case report
NF1 splice_donor_variant Different Alteration BRD4 inhibitor Responsive MPN Pre-clinical
NF1 splice_donor_variant Different Alteration Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 splice_donor_variant Different Alteration Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 splice_donor_variant Different Alteration Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 splice_donor_variant Different Alteration MEK inhibitor Responsive G, LK Pre-clinical
NF1 splice_donor_variant Different Alteration Vinblastine (Chemotherapy) Responsive G Early trials
NF1 splice_donor_variant Different Alteration Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 splice_donor_variant Different Alteration Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 splice_donor_variant Different Alteration Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 splice_donor_variant Different Alteration MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 splice_donor_variant Different Alteration Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 splice_donor_variant Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 splice_donor_variant Different Alteration Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 splice_donor_variant Different Alteration Everolimus (MTOR inhibitor) Responsive SG, HNC Case report
NF1 splice_donor_variant Different Alteration Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 splice_donor_variant Different Alteration Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 splice_donor_variant Different Alteration Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 splice_donor_variant Different Alteration Retinoic Acid Resistant NB Pre-clinical
NF1 splice_donor_variant Different Alteration Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 splice_donor_variant Different Alteration Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 splice_donor_variant Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive PLEN, MPN Pre-clinical
NF1 splice_donor_variant Different Alteration Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 splice_donor_variant Different Alteration Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 splice_donor_variant Different Alteration AURK inhibitor Responsive MPN Pre-clinical
NF1 splice_donor_variant Different Alteration Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 splice_donor_variant Different Alteration PD1 Ab inhibitor Responsive CM Early trials
NF1 splice_donor_variant Different Alteration MEK inhibitor Responsive MPN Pre-clinical
NF1 splice_donor_variant Different Alteration KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
TP53 P278S Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 P278S Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 P278S Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 P278S Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 P278S Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 P278S Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 P278S Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P278S Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P278S Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 P278S Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 P278S Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 P278S Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P278S Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 P278S Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P278S Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
KMT2D W1491* Complete Match Bicalutamide (AR inhibitor) Responsive LUSC Pre-clinical
RB1 Q383* Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 Q383* Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 Q383* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 Q383* Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 Q383* Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 Q383* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 Q383* Different Alteration HDAC inhibitor Responsive RB Pre-clinical
FGFR2 L262P Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 L262P Different Alteration FGFR inhibitor Responsive BT Early trials
PIK3CA E545G), PIK3CA MUT (E545K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E545G), PIK3CA MUT (E545K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E545G), PIK3CA MUT (E545K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E545G), PIK3CA MUT (E545K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E545G), PIK3CA MUT (E545K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E545G), PIK3CA MUT (E545K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E545G), PIK3CA MUT (E545K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E545G), PIK3CA MUT (E545K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E545G), PIK3CA MUT (E545K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E545G), PIK3CA MUT (E545K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E545G), PIK3CA MUT (E545K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E545G), PIK3CA MUT (E545K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E545G), PIK3CA MUT (E545K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E545G), PIK3CA MUT (E545K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
ERBB4 3-UTRSNV Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
ALK E780D Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK E780D Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK E780D Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK E780D Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK E780D Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK E780D Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK E780D Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK E780D Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK E780D Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK E780D Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK E780D Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK E780D Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK E780D Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK E780D Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK E780D Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK E780D Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK E780D Different Alteration ALK inhibitor Responsive COREAD Case report
ALK E780D Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK E780D Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
NOTCH2 V1015A Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
EGFR S246S Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR S246S Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
ROS1 L567L), ROS1 MUT* (I745I), ROS1 MUT* (3-UTRSNV Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 L567L), ROS1 MUT* (I745I), ROS1 MUT* (3-UTRSNV Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 L567L), ROS1 MUT* (I745I), ROS1 MUT* (3-UTRSNV Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 L567L), ROS1 MUT* (I745I), ROS1 MUT* (3-UTRSNV Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 L567L), ROS1 MUT* (I745I), ROS1 MUT* (3-UTRSNV Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
MET P485L Different Alteration Crizotinib (ALK inhibitor) Responsive G Case report
PTEN splice_acceptor_variant Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN splice_acceptor_variant Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN splice_acceptor_variant Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN splice_acceptor_variant Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN splice_acceptor_variant Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN splice_acceptor_variant Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN splice_acceptor_variant Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN splice_acceptor_variant Complete Match PARP inhibitor Responsive ED Case report
PTEN splice_acceptor_variant Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN splice_acceptor_variant Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN splice_acceptor_variant Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN splice_acceptor_variant Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN splice_acceptor_variant Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN splice_acceptor_variant Complete Match AKT inhibitor Responsive PA Case report
PTEN splice_acceptor_variant Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN splice_acceptor_variant Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN splice_acceptor_variant Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN splice_acceptor_variant Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN splice_acceptor_variant Different Alteration PARP inhibitor Responsive ED Case report
PTEN splice_acceptor_variant Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN splice_acceptor_variant Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN splice_acceptor_variant Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN splice_acceptor_variant Different Alteration AKT inhibitor Responsive PA Case report
PTEN splice_acceptor_variant Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN splice_acceptor_variant Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
KMT2A P654P Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A P654P Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A P654P Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A P654P Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A P654P Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A P654P Different Alteration DOT1L inhibitor Responsive AML Early trials
ERBB4 splice_acceptor_variant Different Mutation Lapatinib (ERBB2 inhibitor) Responsive CM Pre-clinical
ERBB4 splice_acceptor_variant Different Mutation ERBB2 inhibitor Resistant BRCA Case report
ERBB4 splice_acceptor_variant Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
TP53 E294* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 E294* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 E294* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 E294* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 E294* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 E294* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E294* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E294* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E294* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 E294* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 E294* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 E294* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E294* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 E294* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E294* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
DNMT3A R882H Complete Match Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
AKT1 L52R Different Mutation BRAF inhibitor Resistant CM Case report
AKT1 L52R Different Mutation allosteric AKT inhibitor Responsive CANCER Early trials
AKT1 L52R Different Mutation non-allosteric AKT inhibitor Responsive CANCER Early trials
AKT1 L52R Different Mutation PI3K pathway inhibitor Responsive HNSC Case report
AKT1 L52R Different Mutation Temsirolimus (MTOR inhibitor) Responsive ED Early trials
AKT1 L52R Different Mutation AKT inhibitor Responsive CANCER Pre-clinical
AKT1 L52R Different Mutation Everolimus (MTOR inhibitor) Responsive FH Case report
ESR1 E380Q Different Mutation Fulvestrant (Hormonal therapy) Resistant BRCA Pre-clinical
ESR1 E380Q Complete Match novel ER degrader Responsive BRCA Case report
ESR1 E380Q Complete Match Tamoxifen (Hormonal therapy) Resistant BRCA Early trials
ESR1 E380Q Complete Match Exemestane (Hormonal therapy) Resistant BRCA Late trials
ESR1 E380Q Complete Match Fluvestrant (Hormonal therapy) Responsive BRCA Late trials
ESR1 E380Q Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
ALK D525N Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK D525N Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK D525N Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK D525N Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK D525N Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK D525N Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK D525N Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK D525N Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK D525N Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK D525N Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK D525N Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK D525N Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK D525N Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK D525N Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK D525N Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK D525N Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK D525N Different Alteration ALK inhibitor Responsive COREAD Case report
ALK D525N Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK D525N Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
PIK3CA R108H Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA R108H Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA R108H Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA R108H Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA R108H Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA R108H Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA R108H Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA R108H Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA R108H Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA R108H Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA R108H Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA R108H Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA R108H Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA R108H Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
RAF1 Q253* Different Alteration Sorafenib (Pan-TK inhibitor) Responsive PRAD Pre-clinical
RAF1 Q253* Different Alteration Pan-RAF inhibitor Responsive PRAD Pre-clinical
RAF1 Q253* Different Alteration U0126 (MEK inhibitor) Responsive PRAD Pre-clinical
BRAF K698R Different Alteration Sorafenib (Pan-TK inhibitor) Responsive CM, LUAD, PRAD Pre-clinical
BRAF K698R Different Alteration MEK inhibitor Responsive LUAD, CM, PRAD Pre-clinical
BRAF K698R Different Alteration Selumetinib (MEK inhibitor) Responsive OV Case report
BRAF K698R Different Alteration BRAF inhibitor;MEK inhibitor Responsive LUAD Case report
STAG2 R216* Complete Match PARP inhibitor Responsive G Pre-clinical
PTEN Y88* Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN Y88* Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN Y88* Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN Y88* Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN Y88* Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN Y88* Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN Y88* Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN Y88* Complete Match PARP inhibitor Responsive ED Case report
PTEN Y88* Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN Y88* Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN Y88* Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN Y88* Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN Y88* Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN Y88* Complete Match AKT inhibitor Responsive PA Case report
PTEN Y88* Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN Y88* Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN Y88* Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN Y88* Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN Y88* Different Alteration PARP inhibitor Responsive ED Case report
PTEN Y88* Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN Y88* Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN Y88* Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN Y88* Different Alteration AKT inhibitor Responsive PA Case report
PTEN Y88* Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN Y88* Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PIK3CA E453K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E453K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E453K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E453K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E453K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E453K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E453K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E453K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E453K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E453K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E453K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E453K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E453K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E453K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
TP53 R282W Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R282W Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R282W Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R282W Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R282W Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R282W Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R282W Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R282W Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R282W Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R282W Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R282W Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R282W Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R282W Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R282W Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R282W Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NTRK3 S359S Different Alteration IGF1R inhibitor Responsive BRCA Pre-clinical
NTRK3 S359S Different Alteration PI3K pathway inhibitor Responsive BRCA Pre-clinical
NTRK3 S359S Different Alteration Midostaurin (Pan-TK inhibitor) Responsive BRCA Pre-clinical
FAT1 Q3825* Complete Match BET inhibitor Responsive HNSC Pre-clinical
RB1 R552* Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 R552* Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 R552* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 R552* Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 R552* Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 R552* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 R552* Different Alteration HDAC inhibitor Responsive RB Pre-clinical
TP53 V173M Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 V173M Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 V173M Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 V173M Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 V173M Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 V173M Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 V173M Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V173M Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V173M Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 V173M Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 V173M Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 V173M Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V173M Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 V173M Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V173M Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 L265R Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 L265R Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 L265R Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 L265R Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 L265R Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 L265R Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 L265R Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L265R Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L265R Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 L265R Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 L265R Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 L265R Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L265R Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 L265R Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L265R Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3R1 splice_donor_variant Complete Match AKT inhibitor Responsive G Pre-clinical
PIK3R1 splice_donor_variant Complete Match PI3K pathway inhibitor Responsive ED Case report
PTPRD G574* Complete Match IGF1R inhibitor Responsive S Case report
PDGFB K155N Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive DFS FDA guidelines
TP53 R248W Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R248W Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R248W Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R248W Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R248W Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R248W Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R248W Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R248W Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R248W Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R248W Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R248W Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R248W Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R248W Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R248W Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R248W Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
FGFR2 N550K), FGFR2 MUT (N550K Different Alteration FGFR inhibitor Resistant CH Early trials
FGFR2 N550K Different Mutation FGFR inhibitor Responsive LUSC Pre-clinical
FGFR2 N550K Complete Match Dovitinib (FGFR inhibitor) Resistant ED Pre-clinical
FGFR2 N550K Complete Match Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive ED Pre-clinical
FGFR2 N550K Complete Match FGFR inhibitor Responsive ED Pre-clinical
FGFR2 N550K Different Mutation FGFR inhibitor Responsive L Pre-clinical
FGFR2 N550K Different Mutation FGFR inhibitor Responsive ED Pre-clinical
FGFR2 N550K Different Mutation FGFR inhibitor Responsive BT Case report
FGFR2 N550K Different Alteration FGFR inhibitor Responsive ST Early trials
FGFR2 N550K Different Alteration FGFR inhibitor Responsive BRCA Case report
FGFR2 N550K Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 N550K Different Alteration FGFR inhibitor Responsive BT Early trials
BRCA1 G1788V Complete Match Chemotherapy (PARP inhibitor;Chemotherapy) Responsive OV Early trials
BRCA1 G1788V Complete Match PARP inhibitor Responsive BRCA Early trials
BRCA1 G1788V Complete Match PARP inhibitor;Chemotherapy Responsive OV Early trials
BRCA1 G1788V Complete Match Rucaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 G1788V Complete Match Platinum Agent (Chemotherapy) Responsive BRCA Early trials
BRCA1 G1788V Complete Match WEE1 inhibitor Responsive CANCER Case report
BRCA1 G1788V Complete Match Platinum Agent (Chemotherapy) Responsive OV Late trials
BRCA1 G1788V Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
BRCA1 G1788V Complete Match Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) Responsive BRCA Early trials
BRCA1 G1788V Complete Match PARP inhibitor Responsive PA Case report
BRCA1 G1788V Complete Match Olaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 G1788V Different Alteration PARP inhibitor Responsive OV Pre-clinical
NOTCH2 R268S Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
TP53 L252P Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 L252P Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 L252P Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 L252P Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 L252P Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 L252P Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 L252P Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L252P Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L252P Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 L252P Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 L252P Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 L252P Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L252P Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 L252P Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L252P Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ABL1 P112Q Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
ABL1 P112Q Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
ABL1 P112Q Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
ABL1 P112Q Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
ABL1 P112Q Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
ABL1 P112Q Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
TP53 R213* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R213* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R213* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R213* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R213* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R213* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R213* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R213* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R213* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R213* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R213* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R213* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R213* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R213* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R213* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PTEN K128N Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN K128N Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN K128N Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN K128N Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN K128N Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN K128N Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN K128N Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN K128N Complete Match PARP inhibitor Responsive ED Case report
PTEN K128N Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN K128N Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN K128N Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN K128N Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN K128N Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN K128N Complete Match AKT inhibitor Responsive PA Case report
PTEN K128N Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN K128N Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN K128N Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN K128N Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN K128N Different Alteration PARP inhibitor Responsive ED Case report
PTEN K128N Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN K128N Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN K128N Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN K128N Different Alteration AKT inhibitor Responsive PA Case report
PTEN K128N Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN K128N Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
EZH2 S639* Different Mutation EZH2 inhibitor Responsive LY Pre-clinical
EZH2 S639* Different Mutation EZH2 inhibitor Responsive LY Early trials
PML P419P Different Alteration Volasertib (PLK1 inhibitor) Responsive AML Early trials
PML P419P Different Alteration Tretinoin (Retinoid) Responsive APML FDA guidelines
PML P419P Different Alteration Tretinoin;Arsenic Trioxide (Retinoid;Chemotherapy) Responsive AML FDA guidelines
KMT2A C2068Y Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A C2068Y Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A C2068Y Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A C2068Y Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A C2068Y Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A C2068Y Different Alteration DOT1L inhibitor Responsive AML Early trials
TP53 G245D Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 G245D Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 G245D Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 G245D Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 G245D Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 G245D Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 G245D Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G245D Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G245D Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 G245D Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 G245D Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 G245D Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G245D Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 G245D Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G245D Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 H193L Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 H193L Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 H193L Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 H193L Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 H193L Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 H193L Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 H193L Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H193L Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H193L Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 H193L Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 H193L Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 H193L Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H193L Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 H193L Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H193L Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
BCR Q300H Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
BCR Q300H Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
BCR Q300H Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR Q300H Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR Q300H Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
BCR Q300H Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
ALK M301I Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK M301I Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK M301I Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK M301I Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK M301I Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK M301I Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK M301I Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK M301I Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK M301I Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK M301I Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK M301I Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK M301I Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK M301I Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK M301I Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK M301I Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK M301I Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK M301I Different Alteration ALK inhibitor Responsive COREAD Case report
ALK M301I Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK M301I Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
ERBB4 N278S Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
TP53 V216M Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 V216M Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 V216M Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 V216M Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 V216M Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 V216M Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 V216M Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V216M Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V216M Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 V216M Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 V216M Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 V216M Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V216M Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 V216M Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V216M Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
EGFR C526S Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR C526S Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
TP53 R273P Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R273P Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R273P Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R273P Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R273P Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R273P Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R273P Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R273P Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R273P Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R273P Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R273P Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R273P Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R273P Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R273P Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R273P Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ROS1 T2266R Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 T2266R Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 T2266R Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 T2266R Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 T2266R Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
EGFR Y900Y Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR Y900Y Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
TP53 E198* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 E198* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 E198* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 E198* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 E198* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 E198* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E198* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E198* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E198* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 E198* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 E198* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 E198* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E198* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 E198* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E198* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA H1047R), PIK3CA MUT (M1004I Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA H1047R), PIK3CA MUT (M1004I Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA H1047R), PIK3CA MUT (M1004I Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
PDGFRA E571K Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive MDPS, MDS, ECL, HES FDA guidelines
ATM splice_donor_variant Different Mutation AZD6738 (ATR inhibitor) Responsive BCL Early trials
ATM splice_donor_variant Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
ATM splice_donor_variant Complete Match Olaparib (PARP inhibitor) Responsive ST, PRAD Early trials
ATM splice_donor_variant Complete Match PARP inhibitor Responsive ST Early trials
ATM splice_donor_variant Complete Match ATR inhibitor Responsive COREAD Case report
ATM splice_donor_variant Complete Match DNA-PKc inhibitor Responsive LY Pre-clinical
ATM splice_donor_variant Complete Match Temozolomide (Chemotherapy) Responsive G Pre-clinical
ATM splice_donor_variant Complete Match PD1/PDL1 inhibitor Responsive UTH Early trials
ATM splice_donor_variant Different Alteration PD1/PDL1 inhibitor Responsive UTH Early trials
ATM splice_donor_variant Different Alteration DNA-PKc inhibitor Responsive LY Pre-clinical
ATM splice_donor_variant Different Alteration PARP inhibitor Responsive ST Early trials
ATM splice_donor_variant Different Alteration ATR inhibitor Responsive COREAD Case report
ATM splice_donor_variant Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
TP53 V197G Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 V197G Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 V197G Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 V197G Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 V197G Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 V197G Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 V197G Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V197G Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V197G Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 V197G Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 V197G Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 V197G Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V197G Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 V197G Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V197G Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
SETD2 S180* Complete Match WEE1 inhibitor Responsive CANCER Pre-clinical
SETD2 S180* Different Alteration WEE1 inhibitor Responsive CANCER Pre-clinical
TP53 Y205C Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Y205C Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Y205C Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Y205C Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Y205C Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Y205C Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Y205C Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y205C Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y205C Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Y205C Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Y205C Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Y205C Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y205C Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Y205C Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y205C Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
KMT2A Q900* Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A Q900* Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A Q900* Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A Q900* Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A Q900* Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A Q900* Different Alteration DOT1L inhibitor Responsive AML Early trials
ATM R2993* Different Mutation AZD6738 (ATR inhibitor) Responsive BCL Early trials
ATM R2993* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
ATM R2993* Complete Match Olaparib (PARP inhibitor) Responsive ST, PRAD Early trials
ATM R2993* Complete Match PARP inhibitor Responsive ST Early trials
ATM R2993* Complete Match ATR inhibitor Responsive COREAD Case report
ATM R2993* Complete Match DNA-PKc inhibitor Responsive LY Pre-clinical
ATM R2993* Complete Match Temozolomide (Chemotherapy) Responsive G Pre-clinical
ATM R2993* Complete Match PD1/PDL1 inhibitor Responsive UTH Early trials
ATM R2993* Different Alteration PD1/PDL1 inhibitor Responsive UTH Early trials
ATM R2993* Different Alteration DNA-PKc inhibitor Responsive LY Pre-clinical
ATM R2993* Different Alteration PARP inhibitor Responsive ST Early trials
ATM R2993* Different Alteration ATR inhibitor Responsive COREAD Case report
ATM R2993* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
PDGFRA R822H Different Alteration Sunitinib (Pan-TK inhibitor) Responsive R Pre-clinical
PDGFRA R822H Complete Match Sunitinib (Pan-TK inhibitor) Responsive GIST NCCN guidelines
PDGFRA R822H Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive GIST NCCN guidelines
PDGFRA R822H Complete Match Regorafenib (Pan-kinase inhibitor) Responsive GIST NCCN guidelines
PDGFRA R822H Different Mutation Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive CM Pre-clinical
PDGFRA R822H Different Mutation Crenolanib (FLT3 inhibitor) Responsive CM Pre-clinical
PDGFRA R822H Different Mutation Imatinib (BCR-ABL inhibitor & KIT inhibitor) Resistant HES Case report
PDGFRA R822H Different Mutation Crenolanib (FLT3 inhibitor) Responsive GIST Early trials
PDGFRA R822H Different Mutation HSP90 inhibitor Responsive GIST Pre-clinical
PDGFRA R822H Different Mutation HSP90 inhibitor (HSP90 inhibitor) Responsive GIST Pre-clinical
PDGFRA R822H Different Mutation Dasatinib (BCR-ABL inhibitor) Responsive GIST Pre-clinical
PDGFRA R822H Different Mutation Imatinib (BCR-ABL inhibitor & KIT inhibitor) Resistant GIST Late trials
PDGFRA R822H Different Mutation PDGFR inhibitor Responsive GIST Early trials
PDGFRA R822H Different Mutation Sunitinib (Pan-TK inhibitor) Resistant GIST Late trials
PDGFRA R822H Different Mutation Sorafenib (Pan-TK inhibitor) Responsive GIST Early trials
PDGFRA R822H Different Mutation Sunitinib (Pan-TK inhibitor) Responsive GIST Late trials
PDGFRA R822H Different Alteration PDGFR inhibitor No Responsive G Pre-clinical
PDGFRA R822H Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive MDPS, MDS, ECL, HES FDA guidelines
RB1 S215* Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 S215* Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 S215* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 S215* Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 S215* Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 S215* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 S215* Different Alteration HDAC inhibitor Responsive RB Pre-clinical
AKT3 3-UTRSNV Different Alteration ATP competitive AKT inhibitor Responsive BRCA Pre-clinical
MET Y390Y Different Alteration Crizotinib (ALK inhibitor) Responsive G Case report
EGFR S198S Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR S198S Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
ATM Q2269* Different Mutation AZD6738 (ATR inhibitor) Responsive BCL Early trials
ATM Q2269* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
ATM Q2269* Complete Match Olaparib (PARP inhibitor) Responsive ST, PRAD Early trials
ATM Q2269* Complete Match PARP inhibitor Responsive ST Early trials
ATM Q2269* Complete Match ATR inhibitor Responsive COREAD Case report
ATM Q2269* Complete Match DNA-PKc inhibitor Responsive LY Pre-clinical
ATM Q2269* Complete Match Temozolomide (Chemotherapy) Responsive G Pre-clinical
ATM Q2269* Complete Match PD1/PDL1 inhibitor Responsive UTH Early trials
ATM Q2269* Different Alteration PD1/PDL1 inhibitor Responsive UTH Early trials
ATM Q2269* Different Alteration DNA-PKc inhibitor Responsive LY Pre-clinical
ATM Q2269* Different Alteration PARP inhibitor Responsive ST Early trials
ATM Q2269* Different Alteration ATR inhibitor Responsive COREAD Case report
ATM Q2269* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
TP53 E51* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 E51* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 E51* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 E51* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 E51* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 E51* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E51* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E51* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E51* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 E51* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 E51* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 E51* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E51* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 E51* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E51* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ARID1A S711* Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A S711* Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A S711* Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A S711* Complete Match ATR inhibitor Responsive CANCER Pre-clinical
CDH1 Q255* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
CDKN1A S98* Complete Match CDK2/4 inhibitor Responsive CANCER Pre-clinical
CDKN1A S98* Different Alteration CDK2/4 inhibitor Responsive CANCER Pre-clinical
BRD4 P15L Different Alteration BET inhibitor Responsive NMC Case report
PTEN H123D Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN H123D Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN H123D Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN H123D Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN H123D Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN H123D Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN H123D Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN H123D Complete Match PARP inhibitor Responsive ED Case report
PTEN H123D Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN H123D Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN H123D Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN H123D Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN H123D Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN H123D Complete Match AKT inhibitor Responsive PA Case report
PTEN H123D Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN H123D Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN H123D Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN H123D Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN H123D Different Alteration PARP inhibitor Responsive ED Case report
PTEN H123D Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN H123D Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN H123D Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN H123D Different Alteration AKT inhibitor Responsive PA Case report
PTEN H123D Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN H123D Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
NOTCH2 L566F Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
KRAS G12C Complete Match Panitumumab (EGFR mAb inhibitor) Resistant COREAD FDA guidelines
KRAS G12C Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD FDA guidelines
KRAS G12C Different Mutation Cetuximab (EGFR mAb inhibitor) No Responsive COREAD Late trials
KRAS G12C Complete Match MEK inhibitor Responsive ALL Pre-clinical
KRAS G12C Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Resistant GIST Case report
KRAS G12C Complete Match MEK inhibitor Responsive OV, CER, AML Pre-clinical
KRAS G12C Complete Match Abemaciclib (CDK4/6 inhibitor) Responsive L Early trials
KRAS G12C Complete Match MEK inhibitor;PI3K pathway inhibitor Responsive COREAD Pre-clinical
KRAS G12C Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD NCCN guidelines
KRAS G12C Complete Match Sorafenib;MEK inhibitor (Pan-TK inhibitor;MEK inhibitor) Responsive HC Early trials
KRAS G12C Complete Match EGFR inhibitor Resistant L NCCN guidelines
KRAS G12C Complete Match CDK4 inhibitor Responsive L Pre-clinical
KRAS G12C Complete Match Selumetinib (MEK inhibitor) Responsive NSCLC Early trials
KRAS G12C Complete Match BET inhibitor Responsive L Pre-clinical
KRAS G12C Complete Match Decitabine;BCL2 inhibitor (Chemotherapy;BCL2 inhibitor) Responsive OV Pre-clinical
KRAS G12C Complete Match FAK inhibitor Responsive L Pre-clinical
KRAS G12C Complete Match EGFR inhibitor Resistant NSCLC Pre-clinical
KRAS G12C Complete Match EZH2 inhibitor Resistant CANCER Pre-clinical
KRAS G12C Complete Match MEK inhibitor Responsive BT, L Early trials
KRAS G12C Complete Match MEK inhibitor;IGF1R inhibitor Responsive COREAD Pre-clinical
KRAS G12C Complete Match MTOR inhibitor;BH3 mimetics Responsive COREAD Pre-clinical
KRAS G12C Complete Match EGFR mAb inhibitor;MEK inhibitor Responsive COREAD Pre-clinical
KRAS G12C Complete Match pan-RAF inhibitor Responsive ED Case report
KRAS G12C Complete Match EGFR mAb inhibitor Resistant ST Pre-clinical
KRAS G12C Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive L Early trials
KRAS G12C Complete Match Selumetinib (MEK inhibitor) No Responsive L Early trials
KRAS G12C Complete Match CDK4/6 inhibitor;MEK inhibitor Responsive L Early trials
KRAS G12C Complete Match Trametinib;Ponatinib (MEK inhibitor;BCR-ABL inhibitor & Pan-TK inhibitor) Responsive LUAD Pre-clinical
KRAS G12C Complete Match Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Resistant COREAD Late trials
KRAS G12C Complete Match pan-RAF inhibitor Responsive L Early trials
KRAS G12C Complete Match JAK/TBK1/IKKε inhibitor Responsive L Pre-clinical
KRAS G12C Complete Match FAS inhibitor Responsive L Case report
KRAS G12C Complete Match HSP90 inhibitor Responsive L Pre-clinical
KRAS G12C Complete Match ERK inhibitor Responsive COREAD Pre-clinical
KRAS G12C Complete Match PI3K pathway inhibitor;MEK inhibitor No Responsive PA Early trials
KRAS G12C Complete Match MEK inhibitor;BCL-XL inhibitor Responsive COREAD Pre-clinical
KRAS G12C Complete Match Gemcitabine;MEK inhibitor (Chemotherapy;MEK inhibitor) Responsive PA Early trials
KRAS G12C Complete Match Panitumumab (EGFR mAb inhibitor) Resistant COREAD NCCN guidelines
KRAS G12C Complete Match PI3K pathway inhibitor Resistant ED Pre-clinical
KRAS G12C Complete Match CDK4/6 inhibitor;MEK inhibitor Responsive CESC Pre-clinical
KRAS G12C Different Alteration BRAF inhibitor;MEK inhibitor Resistant COREAD Case report
KRAS G12C Different Alteration BRAF inhibitor;EGFR mAb inhibitor Resistant COREAD Case report
FBXW7 Y545C Complete Match Steroid Responsive ALL Late trials
FBXW7 Y545C Complete Match Tubulin inhibitor Resistant CANCER Pre-clinical
FBXW7 Y545C Different Alteration Sirolimus (MTOR inhibitor) Responsive COREAD Pre-clinical
FBXW7 Y545C Different Alteration Tubulin inhibitor Resistant CANCER Pre-clinical
TP53 F270I Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 F270I Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 F270I Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 F270I Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 F270I Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 F270I Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 F270I Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 F270I Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 F270I Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 F270I Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 F270I Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 F270I Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 F270I Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 F270I Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 F270I Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R273H Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R273H Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R273H Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R273H Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R273H Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R273H Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R273H Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R273H Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R273H Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R273H Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R273H Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R273H Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R273H Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R273H Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R273H Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E285K Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 E285K Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 E285K Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 E285K Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 E285K Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 E285K Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E285K Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E285K Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E285K Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 E285K Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 E285K Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 E285K Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E285K Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 E285K Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E285K Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NTRK1 P695P Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Case report
NTRK1 P695P Different Alteration Pan-TKR inhibitor Responsive CANCER Early trials
NTRK1 P695P Different Alteration Pan-TK inhibitor Responsive LUAD Pre-clinical
NTRK1 P695P Different Alteration Pan-TK inhibitor Responsive COREAD Case report
TP53 D281V Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 D281V Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 D281V Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 D281V Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 D281V Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 D281V Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 D281V Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 D281V Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 D281V Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 D281V Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 D281V Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 D281V Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 D281V Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 D281V Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 D281V Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ERBB3 V104L Different Mutation PI3K pathway inhibitor;MEK inhibitor Responsive CANCER Pre-clinical
ERBB3 V104L Different Mutation Lapatinib (ERBB2 inhibitor) Responsive CANCER Pre-clinical
ERBB3 V104L Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB3 V104L Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB3 V104L Different Mutation Pertuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB3 V104L Different Mutation ERBB3 mAb inhibitor Responsive CANCER Pre-clinical
ERBB3 V104L Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
KRAS G12V Complete Match Panitumumab (EGFR mAb inhibitor) Resistant COREAD FDA guidelines
KRAS G12V Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD FDA guidelines
KRAS G12V Different Mutation Cetuximab (EGFR mAb inhibitor) No Responsive COREAD Late trials
KRAS G12V Complete Match MEK inhibitor Responsive ALL Pre-clinical
KRAS G12V Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Resistant GIST Case report
KRAS G12V Complete Match MEK inhibitor Responsive OV, CER, AML Pre-clinical
KRAS G12V Complete Match Abemaciclib (CDK4/6 inhibitor) Responsive L Early trials
KRAS G12V Complete Match MEK inhibitor;PI3K pathway inhibitor Responsive COREAD Pre-clinical
KRAS G12V Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD NCCN guidelines
KRAS G12V Complete Match Sorafenib;MEK inhibitor (Pan-TK inhibitor;MEK inhibitor) Responsive HC Early trials
KRAS G12V Complete Match EGFR inhibitor Resistant L NCCN guidelines
KRAS G12V Complete Match CDK4 inhibitor Responsive L Pre-clinical
KRAS G12V Complete Match Selumetinib (MEK inhibitor) Responsive NSCLC Early trials
KRAS G12V Complete Match BET inhibitor Responsive L Pre-clinical
KRAS G12V Complete Match Decitabine;BCL2 inhibitor (Chemotherapy;BCL2 inhibitor) Responsive OV Pre-clinical
KRAS G12V Complete Match FAK inhibitor Responsive L Pre-clinical
KRAS G12V Complete Match EGFR inhibitor Resistant NSCLC Pre-clinical
KRAS G12V Complete Match EZH2 inhibitor Resistant CANCER Pre-clinical
KRAS G12V Complete Match MEK inhibitor Responsive BT, L Early trials
KRAS G12V Complete Match MEK inhibitor;IGF1R inhibitor Responsive COREAD Pre-clinical
KRAS G12V Complete Match MTOR inhibitor;BH3 mimetics Responsive COREAD Pre-clinical
KRAS G12V Complete Match EGFR mAb inhibitor;MEK inhibitor Responsive COREAD Pre-clinical
KRAS G12V Complete Match pan-RAF inhibitor Responsive ED Case report
KRAS G12V Complete Match EGFR mAb inhibitor Resistant ST Pre-clinical
KRAS G12V Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive L Early trials
KRAS G12V Complete Match Selumetinib (MEK inhibitor) No Responsive L Early trials
KRAS G12V Complete Match CDK4/6 inhibitor;MEK inhibitor Responsive L Early trials
KRAS G12V Complete Match Trametinib;Ponatinib (MEK inhibitor;BCR-ABL inhibitor & Pan-TK inhibitor) Responsive LUAD Pre-clinical
KRAS G12V Complete Match Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Resistant COREAD Late trials
KRAS G12V Complete Match pan-RAF inhibitor Responsive L Early trials
KRAS G12V Complete Match JAK/TBK1/IKKε inhibitor Responsive L Pre-clinical
KRAS G12V Complete Match FAS inhibitor Responsive L Case report
KRAS G12V Complete Match HSP90 inhibitor Responsive L Pre-clinical
KRAS G12V Complete Match ERK inhibitor Responsive COREAD Pre-clinical
KRAS G12V Complete Match PI3K pathway inhibitor;MEK inhibitor No Responsive PA Early trials
KRAS G12V Complete Match MEK inhibitor;BCL-XL inhibitor Responsive COREAD Pre-clinical
KRAS G12V Complete Match Gemcitabine;MEK inhibitor (Chemotherapy;MEK inhibitor) Responsive PA Early trials
KRAS G12V Complete Match Panitumumab (EGFR mAb inhibitor) Resistant COREAD NCCN guidelines
KRAS G12V Complete Match PI3K pathway inhibitor Resistant ED Pre-clinical
KRAS G12V Complete Match CDK4/6 inhibitor;MEK inhibitor Responsive CESC Pre-clinical
KRAS G12V Different Alteration BRAF inhibitor;MEK inhibitor Resistant COREAD Case report
KRAS G12V Different Alteration BRAF inhibitor;EGFR mAb inhibitor Resistant COREAD Case report
NOTCH1 A2441T Different Alteration Gamma secretase inhibitor Responsive ALL Pre-clinical
NOTCH1 A2441T Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
TP53 C124* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C124* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C124* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C124* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C124* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C124* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C124* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C124* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C124* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C124* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C124* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C124* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C124* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C124* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C124* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA D350G Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA D350G Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA D350G Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA D350G Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA D350G Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA D350G Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA D350G Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA D350G Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA D350G Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA D350G Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA D350G Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA D350G Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA D350G Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA D350G Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
MET V797M Different Alteration Crizotinib (ALK inhibitor) Responsive G Case report
ERBB3 D297Y Different Mutation PI3K pathway inhibitor;MEK inhibitor Responsive CANCER Pre-clinical
ERBB3 D297Y Different Mutation Lapatinib (ERBB2 inhibitor) Responsive CANCER Pre-clinical
ERBB3 D297Y Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB3 D297Y Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB3 D297Y Different Mutation Pertuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB3 D297Y Different Mutation ERBB3 mAb inhibitor Responsive CANCER Pre-clinical
ERBB3 D297Y Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
MET G1364G Different Alteration Crizotinib (ALK inhibitor) Responsive G Case report
MET Q830L Different Alteration Crizotinib (ALK inhibitor) Responsive G Case report
EGFR A1201V Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR A1201V Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
ABL1 splice_acceptor_variant Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
ABL1 splice_acceptor_variant Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
ABL1 splice_acceptor_variant Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
ABL1 splice_acceptor_variant Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
ABL1 splice_acceptor_variant Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
ABL1 splice_acceptor_variant Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
ATM splice_acceptor_variant Different Mutation AZD6738 (ATR inhibitor) Responsive BCL Early trials
ATM splice_acceptor_variant Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
ATM splice_acceptor_variant Complete Match Olaparib (PARP inhibitor) Responsive ST, PRAD Early trials
ATM splice_acceptor_variant Complete Match PARP inhibitor Responsive ST Early trials
ATM splice_acceptor_variant Complete Match ATR inhibitor Responsive COREAD Case report
ATM splice_acceptor_variant Complete Match DNA-PKc inhibitor Responsive LY Pre-clinical
ATM splice_acceptor_variant Complete Match Temozolomide (Chemotherapy) Responsive G Pre-clinical
ATM splice_acceptor_variant Complete Match PD1/PDL1 inhibitor Responsive UTH Early trials
ATM splice_acceptor_variant Different Alteration PD1/PDL1 inhibitor Responsive UTH Early trials
ATM splice_acceptor_variant Different Alteration DNA-PKc inhibitor Responsive LY Pre-clinical
ATM splice_acceptor_variant Different Alteration PARP inhibitor Responsive ST Early trials
ATM splice_acceptor_variant Different Alteration ATR inhibitor Responsive COREAD Case report
ATM splice_acceptor_variant Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
PIK3CA H1047R), PIK3CA MUT (P539R Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA H1047R), PIK3CA MUT (P539R Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA H1047R), PIK3CA MUT (P539R Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
TP53 C135Y Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C135Y Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C135Y Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C135Y Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C135Y Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C135Y Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C135Y Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C135Y Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C135Y Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C135Y Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C135Y Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C135Y Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C135Y Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C135Y Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C135Y Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R248Q Complete Match HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R248Q Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R248Q Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R248Q Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R248Q Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R248Q Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R248Q Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R248Q Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R248Q Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R248Q Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R248Q Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R248Q Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R248Q Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R248Q Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R248Q Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Y220S Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Y220S Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Y220S Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Y220S Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Y220S Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Y220S Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Y220S Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y220S Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y220S Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Y220S Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Y220S Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Y220S Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y220S Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Y220S Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y220S Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NTRK3 V753G Different Alteration IGF1R inhibitor Responsive BRCA Pre-clinical
NTRK3 V753G Different Alteration PI3K pathway inhibitor Responsive BRCA Pre-clinical
NTRK3 V753G Different Alteration Midostaurin (Pan-TK inhibitor) Responsive BRCA Pre-clinical
FGFR2 V342V Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 V342V Different Alteration FGFR inhibitor Responsive BT Early trials
NOTCH1 P2399S Different Alteration Gamma secretase inhibitor Responsive ALL Pre-clinical
NOTCH1 P2399S Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
PTEN C124S Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN C124S Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN C124S Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN C124S Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN C124S Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN C124S Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN C124S Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN C124S Complete Match PARP inhibitor Responsive ED Case report
PTEN C124S Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN C124S Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN C124S Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN C124S Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN C124S Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN C124S Complete Match AKT inhibitor Responsive PA Case report
PTEN C124S Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN C124S Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN C124S Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN C124S Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN C124S Different Alteration PARP inhibitor Responsive ED Case report
PTEN C124S Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN C124S Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN C124S Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN C124S Different Alteration AKT inhibitor Responsive PA Case report
PTEN C124S Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN C124S Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
NOTCH1 S2523L Different Alteration Gamma secretase inhibitor Responsive ALL Pre-clinical
NOTCH1 S2523L Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
EGFR E114K Different Alteration Cetuximab (EGFR mAb inhibitor) Responsive COREAD FDA guidelines
EGFR E114K Different Alteration Panitumumab (EGFR mAb inhibitor) Resistant COREAD FDA guidelines
EGFR E114K Different Mutation Rindopepimut (Vaccine) Responsive GB Late trials
EGFR E114K Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR E114K Different Mutation Gefitinib (EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR E114K Different Mutation HSP90 inhibitor Responsive L Early trials
EGFR E114K Different Mutation Afatinib;Cetuximab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) Responsive L Early trials
EGFR E114K Different Mutation MEK inhibitor Responsive L Pre-clinical
EGFR E114K Different Mutation EGFR TK inhibitor Responsive L Late trials
EGFR E114K Different Mutation Erlotinib (EGFR inhibitor) Responsive NSCLC NCCN guidelines
EGFR E114K Different Mutation Osimertinib (EGFR inhibitor) Resistant L Early trials
EGFR E114K Different Mutation EGFR-TKI's (EGFR inhibitor) Resistant L Late trials
EGFR E114K Different Mutation HSP90 inhibitor Responsive L Case report
EGFR E114K Different Mutation EGFR inhibitor Resistant L Late trials
EGFR E114K Different Mutation Poziotinib (EGFR inhibitor) Responsive L Early trials
EGFR E114K Different Mutation Osimertinib (EGFR inhibitor) Responsive L Pre-clinical
EGFR E114K Different Mutation HSP90 inhibitor (HSP90 inhibitor) Responsive L Early trials
EGFR E114K Different Mutation Erlotinib (EGFR inhibitor) Responsive G Pre-clinical
EGFR E114K Different Mutation Erlotinib (EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR E114K Different Mutation Osimertinib (EGFR inhibitor) Responsive L Early trials
EGFR E114K Different Mutation Rociletinib (EGFR inhibitor) Resistant LUAD Case report
EGFR E114K Different Mutation Panitumumab (EGFR mAb inhibitor) Responsive COREAD Case report
EGFR E114K Different Mutation novel EGFR mAb inhibitor Responsive COREAD Early trials
EGFR E114K Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
EGFR E114K Different Mutation Cetuximab;Sirolimus (EGFR mAb inhibitor;MTOR inhibitor) Responsive HNC Case report
EGFR E114K Different Mutation Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR E114K Different Mutation Gefitinib (EGFR inhibitor) No Responsive HNC Case report
EGFR E114K Different Mutation EGFR inhibitor Responsive L Early trials
EGFR E114K Different Mutation Erlotinib (EGFR inhibitor) Resistant L NCCN/CAP guidelines
EGFR E114K Different Mutation Osimertinib (EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR E114K Different Mutation EGFR inhibitor Responsive NSCLC Late trials
EGFR E114K Different Mutation Afatinib;Nimotuzumab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) Responsive L Early trials
EGFR E114K Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Resistant L NCCN/CAP guidelines
EGFR E114K Different Mutation Erlotinib (EGFR inhibitor) Responsive L Early trials
EGFR E114K Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive L Late trials
EGFR E114K Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Pre-clinical
EGFR E114K Different Mutation Erlotinib (EGFR inhibitor) No Responsive L Case report
EGFR E114K Different Mutation Lapatinib (ERBB2 inhibitor) Responsive ED Case report
EGFR E114K Different Mutation EGFR inhibitor No Responsive G Early trials
EGFR E114K Different Mutation EGFR inhibitor Resistant NSCLC Case report
EGFR E114K Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
EGFR E114K Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant;Resistant COREAD Pre-clinical;Case report
EGFR E114K Different Mutation Cetuximab (EGFR mAb inhibitor) Responsive HNC Case report
EGFR E114K Different Alteration Gefitinib (EGFR inhibitor) Responsive ED Late trials
EGFR E114K Different Alteration Gefitinib (EGFR inhibitor) No Responsive HNC Early trials
EGFR E114K Different Alteration EGFR inhibitor Responsive HNSC Case report
EGFR E114K Different Alteration EGFR inhibitor No Responsive G Early trials
EGFR E114K Different Alteration Erlotinib (EGFR inhibitor) No Responsive L Early trials
EGFR E114K Different Alteration EGFR mAb inhibitor Responsive COREAD Late trials
EGFR E114K Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR E114K Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
AKT3 S375* Different Alteration ATP competitive AKT inhibitor Responsive BRCA Pre-clinical
NTRK1 Q626K Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Case report
NTRK1 Q626K Different Alteration Pan-TKR inhibitor Responsive CANCER Early trials
NTRK1 Q626K Different Alteration Pan-TK inhibitor Responsive LUAD Pre-clinical
NTRK1 Q626K Different Alteration Pan-TK inhibitor Responsive COREAD Case report
ARID1A Q2037* Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A Q2037* Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A Q2037* Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A Q2037* Complete Match ATR inhibitor Responsive CANCER Pre-clinical
ERBB4 T703K Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
TP53 P278T Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 P278T Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 P278T Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 P278T Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 P278T Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 P278T Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 P278T Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P278T Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P278T Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 P278T Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 P278T Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 P278T Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P278T Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 P278T Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P278T Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
HRAS G13R Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive CER Pre-clinical
HRAS G13R Complete Match MEK inhibitor +/- MTOR inhibitor Responsive AML Pre-clinical
HRAS G13R Complete Match MTOR inhibitor Responsive CESC Pre-clinical
HRAS G13R Complete Match Tipifarnib (Farnesyltransferase inhibitor) Responsive CANCER Early trials
ABL1 D482E Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
ABL1 D482E Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
ABL1 D482E Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
ABL1 D482E Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
ABL1 D482E Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
ABL1 D482E Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
TP53 L265P Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 L265P Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 L265P Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 L265P Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 L265P Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 L265P Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 L265P Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L265P Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L265P Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 L265P Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 L265P Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 L265P Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L265P Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 L265P Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L265P Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
CDKN1B S27* Complete Match CDK2/4 inhibitor Responsive CANCER Pre-clinical
CDKN1B S27* Different Alteration CDK2/4 inhibitor Responsive CANCER Pre-clinical
TP53 P151H Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 P151H Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 P151H Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 P151H Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 P151H Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 P151H Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 P151H Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P151H Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P151H Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 P151H Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 P151H Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 P151H Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P151H Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 P151H Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P151H Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R248W), TP53 MUT (L114* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R248W), TP53 MUT (L114* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R248W), TP53 MUT (L114* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R248W), TP53 MUT (L114* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R248W), TP53 MUT (L114* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R248W), TP53 MUT (L114* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R248W), TP53 MUT (L114* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R248W), TP53 MUT (L114* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R248W), TP53 MUT (L114* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R248W), TP53 MUT (L114* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R248W), TP53 MUT (L114* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R248W), TP53 MUT (L114* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R248W), TP53 MUT (L114* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R248W), TP53 MUT (L114* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R248W), TP53 MUT (L114* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 G245S Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 G245S Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 G245S Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 G245S Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 G245S Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 G245S Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 G245S Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G245S Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G245S Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 G245S Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 G245S Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 G245S Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G245S Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 G245S Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G245S Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
EPHA2 CdsStopSNV Different Mutation MTOR inhibitor Responsive LUSC Pre-clinical
EPHA2 CdsStopSNV Different Mutation Dasatinib (BCR-ABL inhibitor) Responsive LUSC Pre-clinical
EPHA2 CdsStopSNV Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive CANCER Pre-clinical
TP53 F270S Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 F270S Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 F270S Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 F270S Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 F270S Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 F270S Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 F270S Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 F270S Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 F270S Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 F270S Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 F270S Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 F270S Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 F270S Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 F270S Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 F270S Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
JAK2 R115I Different Alteration Ruxolitinib (JAK inhibitor) Responsive ALL Pre-clinical
NOTCH2 R1604S Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
BCOR S3* Complete Match Enzastaurin (PKCb inhibitor) Responsive ST Pre-clinical
PDGFRA T361S Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive MDPS, MDS, ECL, HES FDA guidelines
RET T636T Different Alteration Nintedanib (Pan-TK inhibitor) Responsive LUAD Case report
RET T636T Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Early trials
RET T636T Different Alteration RET inhibitor Responsive LUAD Pre-clinical
RET T636T Different Alteration Vandetanib (Pan-TK inhibitor) Responsive LUAD Early trials
RET T636T Different Alteration Sunitinib (Pan-TK inhibitor) Responsive LUAD Early trials
RET T636T Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive THCA Pre-clinical
RET T636T Different Alteration Vandetanib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET T636T Different Alteration Sunitinib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET T636T Different Alteration RET inhibitor Responsive TH Pre-clinical
PIK3CA Q546P Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA Q546P Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA Q546P Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA Q546P Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA Q546P Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA Q546P Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA Q546P Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA Q546P Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA Q546P Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA Q546P Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA Q546P Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA Q546P Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA Q546P Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA Q546P Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
ESR1 5-UTRBlockSubstitution Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
PIK3CA E453K), PIK3CA MUT (E81K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E453K), PIK3CA MUT (E81K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E453K), PIK3CA MUT (E81K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E453K), PIK3CA MUT (E81K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E453K), PIK3CA MUT (E81K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E453K), PIK3CA MUT (E81K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E453K), PIK3CA MUT (E81K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E453K), PIK3CA MUT (E81K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E453K), PIK3CA MUT (E81K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E453K), PIK3CA MUT (E81K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E453K), PIK3CA MUT (E81K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E453K), PIK3CA MUT (E81K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E453K), PIK3CA MUT (E81K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E453K), PIK3CA MUT (E81K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
CDKN1B E105* Complete Match CDK2/4 inhibitor Responsive CANCER Pre-clinical
CDKN1B E105* Different Alteration CDK2/4 inhibitor Responsive CANCER Pre-clinical
NRG1 E579E Different Alteration Lapatinib (ERBB2 inhibitor) Responsive LUAD Pre-clinical
NRG1 E579E Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Case report
NOTCH2 V1666F Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
PTEN K266* Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN K266* Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN K266* Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN K266* Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN K266* Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN K266* Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN K266* Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN K266* Complete Match PARP inhibitor Responsive ED Case report
PTEN K266* Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN K266* Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN K266* Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN K266* Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN K266* Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN K266* Complete Match AKT inhibitor Responsive PA Case report
PTEN K266* Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN K266* Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN K266* Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN K266* Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN K266* Different Alteration PARP inhibitor Responsive ED Case report
PTEN K266* Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN K266* Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN K266* Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN K266* Different Alteration AKT inhibitor Responsive PA Case report
PTEN K266* Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN K266* Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
NOTCH2 G476* Different Mutation Mk-0752 (Gamma secretase inhibitor) Responsive ALL, AML, BRCA Early trials
NOTCH2 G476* Different Mutation OMP-59R5 (NOTCH2 inhibitor) Responsive SOLID Early trials
NOTCH2 G476*), NOTCH2 MUT* (S955N Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
BRD4 T296P Different Alteration BET inhibitor Responsive NMC Case report
CDH1 Q195* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
CDH1 E494* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
NTRK1 R342Q Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Case report
NTRK1 R342Q Different Alteration Pan-TKR inhibitor Responsive CANCER Early trials
NTRK1 R342Q Different Alteration Pan-TK inhibitor Responsive LUAD Pre-clinical
NTRK1 R342Q Different Alteration Pan-TK inhibitor Responsive COREAD Case report
PIK3CA C420R Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA C420R Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA C420R Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA C420R Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA C420R Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA C420R Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA C420R Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA C420R Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA C420R Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA C420R Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA C420R Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA C420R Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA C420R Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA C420R Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
ESR1 P222S Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
NOTCH2 Q921Q Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
TP53 E258Q Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 E258Q Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 E258Q Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 E258Q Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 E258Q Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 E258Q Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E258Q Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E258Q Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E258Q Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 E258Q Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 E258Q Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 E258Q Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E258Q Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 E258Q Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E258Q Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NTRK3 R683S Different Alteration IGF1R inhibitor Responsive BRCA Pre-clinical
NTRK3 R683S Different Alteration PI3K pathway inhibitor Responsive BRCA Pre-clinical
NTRK3 R683S Different Alteration Midostaurin (Pan-TK inhibitor) Responsive BRCA Pre-clinical
PIK3CA E726G Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E726G Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E726G Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E726G Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E726G Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E726G Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E726G Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E726G Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E726G Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E726G Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E726G Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E726G Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E726G Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E726G Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
PIK3CA E545K), PIK3CA MUT (E726K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E545K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E545K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E545K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E545K), PIK3CA MUT (E726K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E545K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E545K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E545K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E545K), PIK3CA MUT (E726K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E545K), PIK3CA MUT (E726K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E545K), PIK3CA MUT (E726K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E545K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E545K), PIK3CA MUT (E726K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E545K), PIK3CA MUT (E726K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
TP53 V274F Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 V274F Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 V274F Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 V274F Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 V274F Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 V274F Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 V274F Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V274F Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V274F Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 V274F Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 V274F Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 V274F Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V274F Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 V274F Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V274F Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ARID1A R1989* Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A R1989* Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A R1989* Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A R1989* Complete Match ATR inhibitor Responsive CANCER Pre-clinical
PTEN R130P Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN R130P Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN R130P Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN R130P Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN R130P Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN R130P Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN R130P Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN R130P Complete Match PARP inhibitor Responsive ED Case report
PTEN R130P Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN R130P Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN R130P Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN R130P Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN R130P Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN R130P Complete Match AKT inhibitor Responsive PA Case report
PTEN R130P Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN R130P Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN R130P Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN R130P Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN R130P Different Alteration PARP inhibitor Responsive ED Case report
PTEN R130P Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN R130P Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN R130P Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN R130P Different Alteration AKT inhibitor Responsive PA Case report
PTEN R130P Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN R130P Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
ALK Q286Q Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK Q286Q Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK Q286Q Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK Q286Q Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK Q286Q Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK Q286Q Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK Q286Q Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK Q286Q Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK Q286Q Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK Q286Q Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK Q286Q Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK Q286Q Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK Q286Q Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK Q286Q Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK Q286Q Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK Q286Q Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK Q286Q Different Alteration ALK inhibitor Responsive COREAD Case report
ALK Q286Q Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK Q286Q Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
TP53 G187S Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 G187S Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 G187S Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 G187S Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 G187S Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 G187S Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 G187S Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G187S Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 G187S Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 G187S Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 G187S Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 G187S Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G187S Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 G187S Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 G187S Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
KMT2A splice_donor_variant Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A splice_donor_variant Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A splice_donor_variant Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A splice_donor_variant Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A splice_donor_variant Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A splice_donor_variant Different Alteration DOT1L inhibitor Responsive AML Early trials
KMT2A splice_acceptor_variant Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A splice_acceptor_variant Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A splice_acceptor_variant Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A splice_acceptor_variant Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A splice_acceptor_variant Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A splice_acceptor_variant Different Alteration DOT1L inhibitor Responsive AML Early trials
TP53 K132N Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 K132N Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 K132N Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 K132N Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 K132N Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 K132N Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 K132N Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 K132N Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 K132N Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 K132N Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 K132N Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 K132N Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 K132N Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 K132N Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 K132N Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NF1 Q682* Different Mutation Vemurafenib (BRAF inhibitor) Resistant CM Pre-clinical
NF1 Q682* Different Mutation Everolimus (MTOR inhibitor) Responsive HNC Case report
NF1 Q682* Complete Match Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 Q682* Complete Match Vinblastine (Chemotherapy) Responsive G Early trials
NF1 Q682* Complete Match KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 Q682* Complete Match Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 Q682* Complete Match Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 Q682* Complete Match Retinoic Acid Resistant NB Pre-clinical
NF1 Q682* Complete Match Everolimus (MTOR inhibitor) Responsive NF Late trials
NF1 Q682* Complete Match Trametinib (MEK inhibitor) Responsive G Case report
NF1 Q682* Complete Match Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 Q682* Complete Match Nilotinib (BCR-ABL inhibitor) Responsive MPN, PLEN Pre-clinical
NF1 Q682* Complete Match MEK inhibitor Responsive MPN Pre-clinical
NF1 Q682* Complete Match Everolimus (MTOR inhibitor) Responsive HNC, SG Case report
NF1 Q682* Complete Match Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 Q682* Complete Match PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 Q682* Complete Match MEK inhibitor Responsive LK, G Pre-clinical
NF1 Q682* Complete Match Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 Q682* Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 Q682* Complete Match AURK inhibitor Responsive MPN Pre-clinical
NF1 Q682* Complete Match MTOR inhibitor Responsive LK, G, MPN Pre-clinical
NF1 Q682* Complete Match Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 Q682* Complete Match Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) Responsive HC Case report
NF1 Q682* Complete Match Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 Q682* Complete Match Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 Q682* Complete Match PD1 Ab inhibitor Responsive CM Early trials
NF1 Q682* Complete Match Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 Q682* Complete Match Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 Q682* Complete Match Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 Q682* Complete Match BRD4 inhibitor Responsive MPN Pre-clinical
NF1 Q682* Complete Match Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 Q682* Complete Match Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 Q682* Complete Match MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 Q682* Complete Match Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 Q682* Complete Match Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 Q682* Complete Match Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 Q682* Different Alteration MTOR inhibitor Responsive MPN, G, LK Pre-clinical
NF1 Q682* Different Alteration PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 Q682* Different Alteration Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 Q682* Different Alteration Trametinib (MEK inhibitor) Responsive G Case report
NF1 Q682* Different Alteration BRD4 inhibitor Responsive MPN Pre-clinical
NF1 Q682* Different Alteration Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 Q682* Different Alteration Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 Q682* Different Alteration Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 Q682* Different Alteration MEK inhibitor Responsive G, LK Pre-clinical
NF1 Q682* Different Alteration Vinblastine (Chemotherapy) Responsive G Early trials
NF1 Q682* Different Alteration Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 Q682* Different Alteration Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 Q682* Different Alteration Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 Q682* Different Alteration MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 Q682* Different Alteration Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 Q682* Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 Q682* Different Alteration Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 Q682* Different Alteration Everolimus (MTOR inhibitor) Responsive SG, HNC Case report
NF1 Q682* Different Alteration Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 Q682* Different Alteration Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 Q682* Different Alteration Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 Q682* Different Alteration Retinoic Acid Resistant NB Pre-clinical
NF1 Q682* Different Alteration Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 Q682* Different Alteration Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 Q682* Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive PLEN, MPN Pre-clinical
NF1 Q682* Different Alteration Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 Q682* Different Alteration Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 Q682* Different Alteration AURK inhibitor Responsive MPN Pre-clinical
NF1 Q682* Different Alteration Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 Q682* Different Alteration PD1 Ab inhibitor Responsive CM Early trials
NF1 Q682* Different Alteration MEK inhibitor Responsive MPN Pre-clinical
NF1 Q682* Different Alteration KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
ROS1 R1311Q Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 R1311Q Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 R1311Q Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 R1311Q Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 R1311Q Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
GATA3 K358* Complete Match Aromatase ihibitor Responsive BRCA Pre-clinical
ALK R1275* Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK R1275* Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK R1275* Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK R1275* Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK R1275* Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK R1275* Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK R1275* Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK R1275* Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK R1275* Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK R1275* Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK R1275* Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK R1275* Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK R1275* Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK R1275* Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK R1275* Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK R1275* Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK R1275* Different Alteration ALK inhibitor Responsive COREAD Case report
ALK R1275* Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK R1275* Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
TP53 T125T Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 T125T Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 T125T Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 T125T Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 T125T Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 T125T Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 T125T Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 T125T Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 T125T Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 T125T Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 T125T Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 T125T Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 T125T Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 T125T Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 T125T Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
FGFR2 G818G Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 G818G Different Alteration FGFR inhibitor Responsive BT Early trials
TP53 R158G Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R158G Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R158G Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R158G Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R158G Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R158G Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R158G Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R158G Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R158G Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R158G Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R158G Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R158G Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R158G Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R158G Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R158G Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA H1047R), PIK3CA MUT (P366R Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA H1047R), PIK3CA MUT (P366R Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA H1047R), PIK3CA MUT (P366R Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
NOTCH2 S2153A Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
ERBB4 P172R Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
RET P117T Different Alteration Nintedanib (Pan-TK inhibitor) Responsive LUAD Case report
RET P117T Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Early trials
RET P117T Different Alteration RET inhibitor Responsive LUAD Pre-clinical
RET P117T Different Alteration Vandetanib (Pan-TK inhibitor) Responsive LUAD Early trials
RET P117T Different Alteration Sunitinib (Pan-TK inhibitor) Responsive LUAD Early trials
RET P117T Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive THCA Pre-clinical
RET P117T Different Alteration Vandetanib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET P117T Different Alteration Sunitinib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET P117T Different Alteration RET inhibitor Responsive TH Pre-clinical
EGFR D916D Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR D916D Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
PTEN splice_donor_variant Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN splice_donor_variant Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN splice_donor_variant Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN splice_donor_variant Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN splice_donor_variant Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN splice_donor_variant Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN splice_donor_variant Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN splice_donor_variant Complete Match PARP inhibitor Responsive ED Case report
PTEN splice_donor_variant Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN splice_donor_variant Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN splice_donor_variant Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN splice_donor_variant Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN splice_donor_variant Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN splice_donor_variant Complete Match AKT inhibitor Responsive PA Case report
PTEN splice_donor_variant Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN splice_donor_variant Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN splice_donor_variant Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN splice_donor_variant Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN splice_donor_variant Different Alteration PARP inhibitor Responsive ED Case report
PTEN splice_donor_variant Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN splice_donor_variant Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN splice_donor_variant Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN splice_donor_variant Different Alteration AKT inhibitor Responsive PA Case report
PTEN splice_donor_variant Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN splice_donor_variant Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PIK3CA M1043I Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA M1043I Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA M1043I Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA M1043I Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA M1043I Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA M1043I Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA M1043I Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA M1043I Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA M1043I Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA M1043I Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA M1043I Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA M1043I Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA M1043I Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA M1043I Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
TP53 E286A Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 E286A Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 E286A Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 E286A Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 E286A Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 E286A Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E286A Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E286A Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E286A Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 E286A Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 E286A Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 E286A Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E286A Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 E286A Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E286A Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NOTCH1 T1997T Different Alteration Gamma secretase inhibitor Responsive ALL Pre-clinical
NOTCH1 T1997T Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
ROS1 N2234K Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 N2234K Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 N2234K Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 N2234K Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 N2234K Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
ERBB4 F1004S Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
RAF1 I122V Different Alteration Sorafenib (Pan-TK inhibitor) Responsive PRAD Pre-clinical
RAF1 I122V Different Alteration Pan-RAF inhibitor Responsive PRAD Pre-clinical
RAF1 I122V Different Alteration U0126 (MEK inhibitor) Responsive PRAD Pre-clinical
PDGFB intron_variant Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive DFS FDA guidelines
ARID1A Q723* Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A Q723* Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A Q723* Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A Q723* Complete Match ATR inhibitor Responsive CANCER Pre-clinical
KMT2A P3059P Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A P3059P Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A P3059P Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A P3059P Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A P3059P Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A P3059P Different Alteration DOT1L inhibitor Responsive AML Early trials
EGFR E257K Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR E257K Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
PIK3R1 R534* Complete Match AKT inhibitor Responsive G Pre-clinical
PIK3R1 R534* Complete Match PI3K pathway inhibitor Responsive ED Case report
RET 3-UTRSNV Different Alteration Nintedanib (Pan-TK inhibitor) Responsive LUAD Case report
RET 3-UTRSNV Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Early trials
RET 3-UTRSNV Different Alteration RET inhibitor Responsive LUAD Pre-clinical
RET 3-UTRSNV Different Alteration Vandetanib (Pan-TK inhibitor) Responsive LUAD Early trials
RET 3-UTRSNV Different Alteration Sunitinib (Pan-TK inhibitor) Responsive LUAD Early trials
RET 3-UTRSNV Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive THCA Pre-clinical
RET 3-UTRSNV Different Alteration Vandetanib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET 3-UTRSNV Different Alteration Sunitinib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET 3-UTRSNV Different Alteration RET inhibitor Responsive TH Pre-clinical
KMT2A S2170N), MLL MUT* (R613Q Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A S2170N), MLL MUT* (R613Q Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A S2170N), MLL MUT* (R613Q Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A S2170N), MLL MUT* (R613Q Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A S2170N), MLL MUT* (R613Q Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A S2170N), MLL MUT* (R613Q Different Alteration DOT1L inhibitor Responsive AML Early trials
NOTCH2 A422T Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
ROS1 3-UTRSNV Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 3-UTRSNV Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 3-UTRSNV Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 3-UTRSNV Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 3-UTRSNV Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
ALK L165L), ALK MUT* (P213L Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK L165L), ALK MUT* (P213L Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK L165L), ALK MUT* (P213L Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK L165L), ALK MUT* (P213L Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK L165L), ALK MUT* (P213L Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK L165L), ALK MUT* (P213L Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK L165L), ALK MUT* (P213L Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK L165L), ALK MUT* (P213L Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK L165L), ALK MUT* (P213L Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK L165L), ALK MUT* (P213L Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK L165L), ALK MUT* (P213L Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK L165L), ALK MUT* (P213L Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK L165L), ALK MUT* (P213L Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK L165L), ALK MUT* (P213L Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK L165L), ALK MUT* (P213L Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK L165L), ALK MUT* (P213L Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK L165L), ALK MUT* (P213L Different Alteration ALK inhibitor Responsive COREAD Case report
ALK L165L), ALK MUT* (P213L Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK L165L), ALK MUT* (P213L Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
RAF1 3-UTRSNV Different Alteration Sorafenib (Pan-TK inhibitor) Responsive PRAD Pre-clinical
RAF1 3-UTRSNV Different Alteration Pan-RAF inhibitor Responsive PRAD Pre-clinical
RAF1 3-UTRSNV Different Alteration U0126 (MEK inhibitor) Responsive PRAD Pre-clinical
JAK2 I77I Different Alteration Ruxolitinib (JAK inhibitor) Responsive ALL Pre-clinical
MET R412G Different Alteration Crizotinib (ALK inhibitor) Responsive G Case report
TP53 S241C Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 S241C Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 S241C Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 S241C Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 S241C Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 S241C Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 S241C Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 S241C Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 S241C Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 S241C Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 S241C Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 S241C Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 S241C Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 S241C Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 S241C Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
BRCA1 splice_acceptor_variant Complete Match Chemotherapy (PARP inhibitor;Chemotherapy) Responsive OV Early trials
BRCA1 splice_acceptor_variant Complete Match PARP inhibitor Responsive BRCA Early trials
BRCA1 splice_acceptor_variant Complete Match PARP inhibitor;Chemotherapy Responsive OV Early trials
BRCA1 splice_acceptor_variant Complete Match Rucaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 splice_acceptor_variant Complete Match Platinum Agent (Chemotherapy) Responsive BRCA Early trials
BRCA1 splice_acceptor_variant Complete Match WEE1 inhibitor Responsive CANCER Case report
BRCA1 splice_acceptor_variant Complete Match Platinum Agent (Chemotherapy) Responsive OV Late trials
BRCA1 splice_acceptor_variant Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
BRCA1 splice_acceptor_variant Complete Match Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) Responsive BRCA Early trials
BRCA1 splice_acceptor_variant Complete Match PARP inhibitor Responsive PA Case report
BRCA1 splice_acceptor_variant Complete Match Olaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 splice_acceptor_variant Different Alteration PARP inhibitor Responsive OV Pre-clinical
AKT3 R66* Different Alteration ATP competitive AKT inhibitor Responsive BRCA Pre-clinical
ARID1A Q548* Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A Q548* Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A Q548* Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A Q548* Complete Match ATR inhibitor Responsive CANCER Pre-clinical
ERBB4 L1008L Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
SF3B1 K666E Different Mutation Spliceosome inhibitor Responsive CANCER Pre-clinical
TP53 C135W Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C135W Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C135W Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C135W Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C135W Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C135W Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C135W Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C135W Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C135W Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C135W Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C135W Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C135W Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C135W Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C135W Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C135W Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA G1007R Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA G1007R Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA G1007R Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA G1007R Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA G1007R Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA G1007R Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA G1007R Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA G1007R Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA G1007R Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA G1007R Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA G1007R Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA G1007R Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA G1007R Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA G1007R Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
NOTCH2 R1630H Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
NOTCH1 Q2487L Different Alteration Gamma secretase inhibitor Responsive ALL Pre-clinical
NOTCH1 Q2487L Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
TP53 E56* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 E56* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 E56* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 E56* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 E56* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 E56* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E56* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E56* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E56* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 E56* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 E56* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 E56* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E56* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 E56* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E56* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA H1047R), PIK3CA MUT (Q546K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA H1047R), PIK3CA MUT (Q546K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA H1047R), PIK3CA MUT (Q546K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
PIK3CA E1037K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E1037K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E1037K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E1037K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E1037K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E1037K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E1037K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E1037K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E1037K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E1037K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E1037K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E1037K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E1037K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E1037K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
NOTCH2 L1717I Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
ROS1 S551F Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 S551F Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 S551F Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 S551F Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 S551F Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
ROS1 R1910* Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 R1910* Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 R1910* Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 R1910* Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 R1910* Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
TP53 R280T Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R280T Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R280T Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R280T Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R280T Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R280T Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R280T Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R280T Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R280T Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R280T Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R280T Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R280T Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R280T Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R280T Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R280T Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
RB1 Q93* Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 Q93* Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 Q93* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 Q93* Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 Q93* Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 Q93* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 Q93* Different Alteration HDAC inhibitor Responsive RB Pre-clinical
IDH1 R132C Complete Match Venetoclax (BCL2 inhibitor) Responsive AML Early trials
IDH1 R132C Complete Match IDH1 inhibitor Responsive AML Early trials
IDH1 R132C Complete Match AG-120 (IDH1 inhibitor) Responsive G Early trials
IDH1 R132C Complete Match Dasatinib (BCR-ABL inhibitor) Responsive CH Early trials
IDH1 R132C Complete Match Ivosidenib (IDH1 inhibitor) Responsive AML Early trials
IDH1 R132C Complete Match BCL2 inhibitor Responsive AML Pre-clinical
IDH1 R132C Complete Match BCL2 inhibitor (BCL2 inhibitor) Responsive AML Pre-clinical
IDH1 R132C Complete Match Dasatinib (BCR-ABL inhibitor) Responsive BT Pre-clinical
IDH1 R132C Complete Match PARP inhibitor Responsive CANCER Pre-clinical
PTEN N48I Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN N48I Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN N48I Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN N48I Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN N48I Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN N48I Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN N48I Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN N48I Complete Match PARP inhibitor Responsive ED Case report
PTEN N48I Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN N48I Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN N48I Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN N48I Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN N48I Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN N48I Complete Match AKT inhibitor Responsive PA Case report
PTEN N48I Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN N48I Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN N48I Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN N48I Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN N48I Different Alteration PARP inhibitor Responsive ED Case report
PTEN N48I Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN N48I Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN N48I Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN N48I Different Alteration AKT inhibitor Responsive PA Case report
PTEN N48I Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN N48I Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
ESR1 L370F Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
BCR E771Q Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
BCR E771Q Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
BCR E771Q Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR E771Q Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR E771Q Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
BCR E771Q Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
PIK3CA H1047R), PIK3CA MUT (E365V Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA H1047R), PIK3CA MUT (E365V Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA H1047R), PIK3CA MUT (E365V Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
PIK3R1 I559T Complete Match AKT inhibitor Responsive G Pre-clinical
PIK3R1 I559T Complete Match PI3K pathway inhibitor Responsive ED Case report
TP53 V173L Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 V173L Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 V173L Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 V173L Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 V173L Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 V173L Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 V173L Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V173L Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V173L Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 V173L Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 V173L Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 V173L Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V173L Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 V173L Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V173L Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA K111E Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA K111E Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA K111E Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA K111E Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA K111E Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA K111E Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA K111E Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA K111E Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA K111E Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA K111E Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA K111E Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA K111E Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA K111E Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA K111E Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
TP53 N247I Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 N247I Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 N247I Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 N247I Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 N247I Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 N247I Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 N247I Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 N247I Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 N247I Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 N247I Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 N247I Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 N247I Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 N247I Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 N247I Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 N247I Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ERBB2 D769Y Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 D769Y Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BRCA FDA guidelines
ERBB2 D769Y Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, BRCA, GEJA FDA guidelines
ERBB2 D769Y Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 D769Y Different Alteration MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) Responsive SOLID Early trials
ERBB2 D769Y Complete Match Lapatinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 D769Y Complete Match Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 D769Y Complete Match Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER, BRCA Pre-clinical
ERBB2 D769Y Different Mutation Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 D769Y Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Case report
ERBB2 D769Y Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA, LUAD Case report
ERBB2 D769Y Different Mutation Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive L Early trials
ERBB2 D769Y Different Mutation Neratinib (ERBB2 inhibitor) Resistant BRCA Case report
ERBB2 D769Y Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Pre-clinical
ERBB2 D769Y Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Case report
ERBB2 D769Y Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 D769Y Different Mutation Lapatinib (ERBB2 inhibitor) Resistant BRCA Pre-clinical
ERBB2 D769Y Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB2 D769Y Complete Match Temsirolimus (MTOR inhibitor) Responsive LUAD Early trials
ERBB2 D769Y Complete Match Dacomitinib (Pan ERBB inhibitor) Responsive NSCLC Early trials
ERBB2 D769Y Complete Match Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 D769Y Different Mutation ERBB2 inhibitor Responsive LUAD Early trials
ERBB2 D769Y Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Early trials
ERBB2 D769Y Different Mutation ERBB2 mAb inhibitor Responsive LUAD Early trials
ERBB2 D769Y Different Mutation Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 D769Y Different Mutation Lapatinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 D769Y Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Early trials
ERBB2 D769Y Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Late trials
ERBB2 D769Y Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 D769Y Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive COREAD Late trials
ERBB2 D769Y Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive OV Early trials
ERBB2 D769Y Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB2 D769Y Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive COREAD Case report
ERBB2 D769Y Different Alteration Rociletinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 D769Y Different Alteration Osimertinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 D769Y Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 D769Y Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
ERBB2 D769Y Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BT Early trials
ERBB2 D769Y Different Alteration Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) Responsive BRCA Early trials
ERBB2 D769Y Different Alteration HER2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 D769Y Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 D769Y Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive ST Early trials
ERBB2 D769Y Different Alteration Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) Responsive BRCA Early trials
ERBB2 D769Y Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, GEJA FDA guidelines
ERBB2 D769Y Different Alteration ERBB2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 D769Y Different Alteration Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 D769Y Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive HNC Case report
ERBB2 D769Y Different Alteration Neratinib (ERBB2 inhibitor) Responsive BRCA Late trials
ERBB2 D769Y Different Alteration Trastuzumab (ERBB2 mAb inhibitor) No Responsive ED Early trials
ERBB2 D769Y Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive ED Pre-clinical
ERBB2 D769Y Different Alteration Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) Responsive ST Early trials
ERBB2 D769Y Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive ST Case report
ERBB2 D769Y Different Alteration EGFR inhibitor Resistant LUAD Pre-clinical
TP53 Y126C Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Y126C Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Y126C Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Y126C Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Y126C Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Y126C Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Y126C Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y126C Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y126C Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Y126C Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Y126C Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Y126C Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y126C Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Y126C Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y126C Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C238F Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C238F Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C238F Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C238F Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C238F Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C238F Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C238F Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C238F Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C238F Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C238F Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C238F Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C238F Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C238F Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C238F Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C238F Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 S127P Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 S127P Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 S127P Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 S127P Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 S127P Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 S127P Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 S127P Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 S127P Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 S127P Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 S127P Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 S127P Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 S127P Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 S127P Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 S127P Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 S127P Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
LRP1B Q400* Complete Match Liposomal Doxorubicin (Chemotherapy) Resistant OV Early trials
LRP1B Q400* Different Alteration Liposomal Doxorubicin (Chemotherapy) Resistant OV Early trials
ROS1 S2326F Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 S2326F Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 S2326F Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 S2326F Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 S2326F Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
NOTCH2 S801L Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
PTEN S287* Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN S287* Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN S287* Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN S287* Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN S287* Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN S287* Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN S287* Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN S287* Complete Match PARP inhibitor Responsive ED Case report
PTEN S287* Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN S287* Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN S287* Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN S287* Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN S287* Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN S287* Complete Match AKT inhibitor Responsive PA Case report
PTEN S287* Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN S287* Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN S287* Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN S287* Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN S287* Different Alteration PARP inhibitor Responsive ED Case report
PTEN S287* Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN S287* Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN S287* Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN S287* Different Alteration AKT inhibitor Responsive PA Case report
PTEN S287* Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN S287* Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
TP53 Y205N Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Y205N Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Y205N Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Y205N Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Y205N Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Y205N Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Y205N Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y205N Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y205N Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Y205N Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Y205N Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Y205N Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y205N Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Y205N Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y205N Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NOTCH2 Y217F Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
BRAF E309* Different Alteration Sorafenib (Pan-TK inhibitor) Responsive CM, LUAD, PRAD Pre-clinical
BRAF E309* Different Alteration MEK inhibitor Responsive LUAD, CM, PRAD Pre-clinical
BRAF E309* Different Alteration Selumetinib (MEK inhibitor) Responsive OV Case report
BRAF E309* Different Alteration BRAF inhibitor;MEK inhibitor Responsive LUAD Case report
ERBB4 intron_variant Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
PTEN L146* Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN L146* Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN L146* Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN L146* Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN L146* Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN L146* Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN L146* Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN L146* Complete Match PARP inhibitor Responsive ED Case report
PTEN L146* Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN L146* Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN L146* Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN L146* Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN L146* Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN L146* Complete Match AKT inhibitor Responsive PA Case report
PTEN L146* Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN L146* Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN L146* Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN L146* Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN L146* Different Alteration PARP inhibitor Responsive ED Case report
PTEN L146* Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN L146* Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN L146* Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN L146* Different Alteration AKT inhibitor Responsive PA Case report
PTEN L146* Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN L146* Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
TP53 H193Y Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 H193Y Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 H193Y Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 H193Y Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 H193Y Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 H193Y Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 H193Y Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H193Y Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H193Y Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 H193Y Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 H193Y Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 H193Y Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H193Y Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 H193Y Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H193Y Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ALK L1169L Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK L1169L Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK L1169L Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK L1169L Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK L1169L Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK L1169L Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK L1169L Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK L1169L Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK L1169L Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK L1169L Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK L1169L Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK L1169L Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK L1169L Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK L1169L Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK L1169L Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK L1169L Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK L1169L Different Alteration ALK inhibitor Responsive COREAD Case report
ALK L1169L Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK L1169L Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
ALK L1048L Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK L1048L Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK L1048L Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK L1048L Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK L1048L Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK L1048L Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK L1048L Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK L1048L Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK L1048L Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK L1048L Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK L1048L Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK L1048L Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK L1048L Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK L1048L Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK L1048L Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK L1048L Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK L1048L Different Alteration ALK inhibitor Responsive COREAD Case report
ALK L1048L Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK L1048L Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
ERBB2 D769H Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 D769H Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BRCA FDA guidelines
ERBB2 D769H Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, BRCA, GEJA FDA guidelines
ERBB2 D769H Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 D769H Different Alteration MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) Responsive SOLID Early trials
ERBB2 D769H Complete Match Lapatinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 D769H Complete Match Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 D769H Complete Match Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER, BRCA Pre-clinical
ERBB2 D769H Different Mutation Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 D769H Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Case report
ERBB2 D769H Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA, LUAD Case report
ERBB2 D769H Different Mutation Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive L Early trials
ERBB2 D769H Different Mutation Neratinib (ERBB2 inhibitor) Resistant BRCA Case report
ERBB2 D769H Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Pre-clinical
ERBB2 D769H Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Case report
ERBB2 D769H Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 D769H Different Mutation Lapatinib (ERBB2 inhibitor) Resistant BRCA Pre-clinical
ERBB2 D769H Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB2 D769H Complete Match Temsirolimus (MTOR inhibitor) Responsive LUAD Early trials
ERBB2 D769H Complete Match Dacomitinib (Pan ERBB inhibitor) Responsive NSCLC Early trials
ERBB2 D769H Complete Match Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 D769H Different Mutation ERBB2 inhibitor Responsive LUAD Early trials
ERBB2 D769H Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Early trials
ERBB2 D769H Different Mutation ERBB2 mAb inhibitor Responsive LUAD Early trials
ERBB2 D769H Different Mutation Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 D769H Different Mutation Lapatinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 D769H Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Early trials
ERBB2 D769H Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Late trials
ERBB2 D769H Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 D769H Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive COREAD Late trials
ERBB2 D769H Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive OV Early trials
ERBB2 D769H Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB2 D769H Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive COREAD Case report
ERBB2 D769H Different Alteration Rociletinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 D769H Different Alteration Osimertinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 D769H Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 D769H Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
ERBB2 D769H Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BT Early trials
ERBB2 D769H Different Alteration Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) Responsive BRCA Early trials
ERBB2 D769H Different Alteration HER2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 D769H Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 D769H Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive ST Early trials
ERBB2 D769H Different Alteration Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) Responsive BRCA Early trials
ERBB2 D769H Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, GEJA FDA guidelines
ERBB2 D769H Different Alteration ERBB2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 D769H Different Alteration Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 D769H Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive HNC Case report
ERBB2 D769H Different Alteration Neratinib (ERBB2 inhibitor) Responsive BRCA Late trials
ERBB2 D769H Different Alteration Trastuzumab (ERBB2 mAb inhibitor) No Responsive ED Early trials
ERBB2 D769H Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive ED Pre-clinical
ERBB2 D769H Different Alteration Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) Responsive ST Early trials
ERBB2 D769H Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive ST Case report
ERBB2 D769H Different Alteration EGFR inhibitor Resistant LUAD Pre-clinical
RET L1101V Different Alteration Nintedanib (Pan-TK inhibitor) Responsive LUAD Case report
RET L1101V Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Early trials
RET L1101V Different Alteration RET inhibitor Responsive LUAD Pre-clinical
RET L1101V Different Alteration Vandetanib (Pan-TK inhibitor) Responsive LUAD Early trials
RET L1101V Different Alteration Sunitinib (Pan-TK inhibitor) Responsive LUAD Early trials
RET L1101V Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive THCA Pre-clinical
RET L1101V Different Alteration Vandetanib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET L1101V Different Alteration Sunitinib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET L1101V Different Alteration RET inhibitor Responsive TH Pre-clinical
ERCC4 E359* Complete Match Cisplatin (Chemotherapy) Responsive OV Pre-clinical
JAK2 R138P Different Alteration Ruxolitinib (JAK inhibitor) Responsive ALL Pre-clinical
RB1 C853* Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 C853* Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 C853* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 C853* Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 C853* Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 C853* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 C853* Different Alteration HDAC inhibitor Responsive RB Pre-clinical
TP53 L194P Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 L194P Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 L194P Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 L194P Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 L194P Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 L194P Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 L194P Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L194P Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L194P Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 L194P Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 L194P Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 L194P Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L194P Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 L194P Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L194P Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 H179Y Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 H179Y Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 H179Y Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 H179Y Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 H179Y Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 H179Y Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 H179Y Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H179Y Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H179Y Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 H179Y Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 H179Y Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 H179Y Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H179Y Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 H179Y Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H179Y Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C141R Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C141R Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C141R Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C141R Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C141R Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C141R Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C141R Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C141R Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C141R Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C141R Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C141R Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C141R Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C141R Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C141R Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C141R Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
EGFR T847K Different Alteration Cetuximab (EGFR mAb inhibitor) Responsive COREAD FDA guidelines
EGFR T847K Different Alteration Panitumumab (EGFR mAb inhibitor) Resistant COREAD FDA guidelines
EGFR T847K Different Mutation Rindopepimut (Vaccine) Responsive GB Late trials
EGFR T847K Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR T847K Different Mutation Gefitinib (EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR T847K Different Mutation HSP90 inhibitor Responsive L Early trials
EGFR T847K Different Mutation Afatinib;Cetuximab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) Responsive L Early trials
EGFR T847K Different Mutation MEK inhibitor Responsive L Pre-clinical
EGFR T847K Different Mutation EGFR TK inhibitor Responsive L Late trials
EGFR T847K Different Mutation Erlotinib (EGFR inhibitor) Responsive NSCLC NCCN guidelines
EGFR T847K Different Mutation Osimertinib (EGFR inhibitor) Resistant L Early trials
EGFR T847K Different Mutation EGFR-TKI's (EGFR inhibitor) Resistant L Late trials
EGFR T847K Different Mutation HSP90 inhibitor Responsive L Case report
EGFR T847K Different Mutation EGFR inhibitor Resistant L Late trials
EGFR T847K Different Mutation Poziotinib (EGFR inhibitor) Responsive L Early trials
EGFR T847K Different Mutation Osimertinib (EGFR inhibitor) Responsive L Pre-clinical
EGFR T847K Different Mutation HSP90 inhibitor (HSP90 inhibitor) Responsive L Early trials
EGFR T847K Different Mutation Erlotinib (EGFR inhibitor) Responsive G Pre-clinical
EGFR T847K Different Mutation Erlotinib (EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR T847K Different Mutation Osimertinib (EGFR inhibitor) Responsive L Early trials
EGFR T847K Different Mutation Rociletinib (EGFR inhibitor) Resistant LUAD Case report
EGFR T847K Different Mutation Panitumumab (EGFR mAb inhibitor) Responsive COREAD Case report
EGFR T847K Different Mutation novel EGFR mAb inhibitor Responsive COREAD Early trials
EGFR T847K Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
EGFR T847K Different Mutation Cetuximab;Sirolimus (EGFR mAb inhibitor;MTOR inhibitor) Responsive HNC Case report
EGFR T847K Different Mutation Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR T847K Different Mutation Gefitinib (EGFR inhibitor) No Responsive HNC Case report
EGFR T847K Different Mutation EGFR inhibitor Responsive L Early trials
EGFR T847K Different Mutation Erlotinib (EGFR inhibitor) Resistant L NCCN/CAP guidelines
EGFR T847K Different Mutation Osimertinib (EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR T847K Different Mutation EGFR inhibitor Responsive NSCLC Late trials
EGFR T847K Different Mutation Afatinib;Nimotuzumab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) Responsive L Early trials
EGFR T847K Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Resistant L NCCN/CAP guidelines
EGFR T847K Different Mutation Erlotinib (EGFR inhibitor) Responsive L Early trials
EGFR T847K Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive L Late trials
EGFR T847K Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Pre-clinical
EGFR T847K Different Mutation Erlotinib (EGFR inhibitor) No Responsive L Case report
EGFR T847K Different Mutation Lapatinib (ERBB2 inhibitor) Responsive ED Case report
EGFR T847K Different Mutation EGFR inhibitor No Responsive G Early trials
EGFR T847K Different Mutation EGFR inhibitor Resistant NSCLC Case report
EGFR T847K Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
EGFR T847K Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant;Resistant COREAD Pre-clinical;Case report
EGFR T847K Different Mutation Cetuximab (EGFR mAb inhibitor) Responsive HNC Case report
EGFR T847K Different Alteration Gefitinib (EGFR inhibitor) Responsive ED Late trials
EGFR T847K Different Alteration Gefitinib (EGFR inhibitor) No Responsive HNC Early trials
EGFR T847K Different Alteration EGFR inhibitor Responsive HNSC Case report
EGFR T847K Different Alteration EGFR inhibitor No Responsive G Early trials
EGFR T847K Different Alteration Erlotinib (EGFR inhibitor) No Responsive L Early trials
EGFR T847K Different Alteration EGFR mAb inhibitor Responsive COREAD Late trials
EGFR T847K Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR T847K Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
ERBB2 I767M Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 I767M Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BRCA FDA guidelines
ERBB2 I767M Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, BRCA, GEJA FDA guidelines
ERBB2 I767M Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 I767M Different Alteration MK2206;Trastuzumab (allosteric AKT inhibitor;ERBB2 mAb inhibitor) Responsive SOLID Early trials
ERBB2 I767M Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 I767M Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Pre-clinical
ERBB2 I767M Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER, BRCA Pre-clinical
ERBB2 I767M Different Mutation Neratinib (ERBB2 inhibitor) Responsive CANCER Early trials
ERBB2 I767M Different Mutation Neratinib (ERBB2 inhibitor) Responsive BRCA Case report
ERBB2 I767M Different Mutation Lapatinib (ERBB2 inhibitor) Responsive BRCA, LUAD Case report
ERBB2 I767M Different Mutation Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive L Early trials
ERBB2 I767M Different Mutation Neratinib (ERBB2 inhibitor) Resistant BRCA Case report
ERBB2 I767M Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Pre-clinical
ERBB2 I767M Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Case report
ERBB2 I767M Different Mutation Lapatinib (ERBB2 inhibitor) Resistant BRCA Pre-clinical
ERBB2 I767M Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive CANCER Pre-clinical
ERBB2 I767M Complete Match Temsirolimus (MTOR inhibitor) Responsive LUAD Early trials
ERBB2 I767M Complete Match Dacomitinib (Pan ERBB inhibitor) Responsive NSCLC Early trials
ERBB2 I767M Complete Match Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 I767M Different Mutation ERBB2 inhibitor Responsive LUAD Early trials
ERBB2 I767M Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Early trials
ERBB2 I767M Different Mutation ERBB2 mAb inhibitor Responsive LUAD Early trials
ERBB2 I767M Different Mutation Neratinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 I767M Different Mutation Lapatinib (ERBB2 inhibitor) Responsive LUAD Early trials
ERBB2 I767M Different Mutation Trastuzumab (ERBB2 mAb inhibitor) Responsive LUAD Early trials
ERBB2 I767M Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BRCA Late trials
ERBB2 I767M Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 I767M Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive COREAD Late trials
ERBB2 I767M Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive OV Early trials
ERBB2 I767M Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive BLCA Case report
ERBB2 I767M Different Alteration Ado-Trastuzumab Emtansine (ERBB2 mAb inhibitor) Responsive COREAD Case report
ERBB2 I767M Different Alteration Rociletinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 I767M Different Alteration Osimertinib (EGFR inhibitor) Resistant LUAD Case report
ERBB2 I767M Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BT Early trials
ERBB2 I767M Different Alteration EGFR mAb inhibitor Resistant COREAD Early trials
ERBB2 I767M Different Alteration Lapatinib (ERBB2 inhibitor) Responsive BT Early trials
ERBB2 I767M Different Alteration Trastuzumab;HSP90 inhibitor (ERBB2 mAb inhibitor;HSP90 inhibitor) Responsive BRCA Early trials
ERBB2 I767M Different Alteration HER2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 I767M Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 I767M Different Alteration Pertuzumab (ERBB2 mAb inhibitor) Responsive ST Early trials
ERBB2 I767M Different Alteration Trastuzumab;Everolimus;Chemotherapy (ERBB2 mAb inhibitor;MTOR inhibitor;Chemotherapy) Responsive BRCA Early trials
ERBB2 I767M Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive ST, GEJA FDA guidelines
ERBB2 I767M Different Alteration ERBB2 inhibitor;CDK4/6 inhibitor Responsive BRCA Pre-clinical
ERBB2 I767M Different Alteration Ado-Trastuzumab Emtansine (EGFR mAb inhibitor) Responsive BRCA FDA guidelines
ERBB2 I767M Different Alteration Trastuzumab (ERBB2 mAb inhibitor) Responsive HNC Case report
ERBB2 I767M Different Alteration Neratinib (ERBB2 inhibitor) Responsive BRCA Late trials
ERBB2 I767M Different Alteration Trastuzumab (ERBB2 mAb inhibitor) No Responsive ED Early trials
ERBB2 I767M Different Alteration Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Responsive ED Pre-clinical
ERBB2 I767M Different Alteration Lapatinib;Chemotherapy (ERBB2 inhibitor;Chemotherapy) Responsive ST Early trials
ERBB2 I767M Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive ST Case report
ERBB2 I767M Different Alteration EGFR inhibitor Resistant LUAD Pre-clinical
PIK3CA H1047R), PIK3CA MUT (R108H Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA H1047R), PIK3CA MUT (R108H Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA H1047R), PIK3CA MUT (R108H Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
TP53 H168P Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 H168P Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 H168P Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 H168P Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 H168P Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 H168P Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 H168P Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H168P Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H168P Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 H168P Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 H168P Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 H168P Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H168P Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 H168P Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H168P Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Q136* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Q136* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Q136* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Q136* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Q136* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Q136* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Q136* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q136* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q136* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Q136* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Q136* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Q136* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q136* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Q136* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q136* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
KMT2A S1002C Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A S1002C Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A S1002C Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A S1002C Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A S1002C Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A S1002C Different Alteration DOT1L inhibitor Responsive AML Early trials
ARID1A Q528* Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A Q528* Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A Q528* Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A Q528* Complete Match ATR inhibitor Responsive CANCER Pre-clinical
ESR1 Y246* Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
TP53 R280* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R280* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R280* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R280* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R280* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R280* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R280* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R280* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R280* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R280* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R280* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R280* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R280* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R280* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R280* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
FLCN S333* Complete Match Everolimus (MTOR inhibitor) Responsive R Case report
FLCN S333* Different Alteration Everolimus (MTOR inhibitor) Responsive TH Case report
TP53 I232S Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 I232S Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 I232S Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 I232S Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 I232S Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 I232S Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 I232S Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 I232S Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 I232S Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 I232S Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 I232S Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 I232S Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 I232S Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 I232S Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 I232S Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ESR1 G274G Different Alteration ESR1 inhibitor Resistant BRCA Pre-clinical
NTRK1 R583H Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Case report
NTRK1 R583H Different Alteration Pan-TKR inhibitor Responsive CANCER Early trials
NTRK1 R583H Different Alteration Pan-TK inhibitor Responsive LUAD Pre-clinical
NTRK1 R583H Different Alteration Pan-TK inhibitor Responsive COREAD Case report
NOTCH2 E1780K Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
ERBB4 E317E Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
PTEN C124G Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN C124G Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN C124G Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN C124G Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN C124G Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN C124G Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN C124G Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN C124G Complete Match PARP inhibitor Responsive ED Case report
PTEN C124G Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN C124G Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN C124G Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN C124G Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN C124G Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN C124G Complete Match AKT inhibitor Responsive PA Case report
PTEN C124G Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN C124G Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN C124G Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN C124G Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN C124G Different Alteration PARP inhibitor Responsive ED Case report
PTEN C124G Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN C124G Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN C124G Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN C124G Different Alteration AKT inhibitor Responsive PA Case report
PTEN C124G Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN C124G Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
RET L846I Different Alteration Nintedanib (Pan-TK inhibitor) Responsive LUAD Case report
RET L846I Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Early trials
RET L846I Different Alteration RET inhibitor Responsive LUAD Pre-clinical
RET L846I Different Alteration Vandetanib (Pan-TK inhibitor) Responsive LUAD Early trials
RET L846I Different Alteration Sunitinib (Pan-TK inhibitor) Responsive LUAD Early trials
RET L846I Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive THCA Pre-clinical
RET L846I Different Alteration Vandetanib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET L846I Different Alteration Sunitinib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET L846I Different Alteration RET inhibitor Responsive TH Pre-clinical
KMT2A T1842A Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A T1842A Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A T1842A Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A T1842A Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A T1842A Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A T1842A Different Alteration DOT1L inhibitor Responsive AML Early trials
JAK2 splice_acceptor_variant Different Alteration Ruxolitinib (JAK inhibitor) Responsive ALL Pre-clinical
ROS1 S932T Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 S932T Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 S932T Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 S932T Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 S932T Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
ERBB4 Y1022C Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
TP53 P278A Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 P278A Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 P278A Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 P278A Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 P278A Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 P278A Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 P278A Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P278A Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 P278A Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 P278A Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 P278A Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 P278A Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P278A Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 P278A Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 P278A Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA V344M Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA V344M Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA V344M Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA V344M Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA V344M Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA V344M Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA V344M Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA V344M Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA V344M Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA V344M Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA V344M Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA V344M Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA V344M Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA V344M Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
NOTCH2 V2469I Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
NRG1 intron_variant Different Alteration Lapatinib (ERBB2 inhibitor) Responsive LUAD Pre-clinical
NRG1 intron_variant Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Case report
DNMT3A G890D Complete Match Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
RB1 splice_acceptor_variant Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 splice_acceptor_variant Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 splice_acceptor_variant Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 splice_acceptor_variant Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 splice_acceptor_variant Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 splice_acceptor_variant Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 splice_acceptor_variant Different Alteration HDAC inhibitor Responsive RB Pre-clinical
ROS1 W1694* Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 W1694* Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 W1694* Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 W1694* Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 W1694* Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
PDGFRA D1075N Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive MDPS, MDS, ECL, HES FDA guidelines
NTRK3 A573V Different Alteration IGF1R inhibitor Responsive BRCA Pre-clinical
NTRK3 A573V Different Alteration PI3K pathway inhibitor Responsive BRCA Pre-clinical
NTRK3 A573V Different Alteration Midostaurin (Pan-TK inhibitor) Responsive BRCA Pre-clinical
STK11 Q123* Different Mutation Everolimus (MTOR inhibitor) Responsive PA Case report
STK11 Q123* Complete Match Phenformin (Anti-diabetic) Responsive LUAD Pre-clinical
STK11 Q123* Complete Match MTOR inhibitor Responsive CANCER Pre-clinical
STK11 Q123* Complete Match BET inhibitor Resistant L Pre-clinical
STK11 Q123* Complete Match PD1 inhibitor Resistant CANCER Early trials
STK11 Q123* Complete Match SRC inhibitor;PI3K/MEK inhibitor Responsive LUAD Pre-clinical
STK11 Q123* Complete Match MEK inhibitor Responsive LUAD Pre-clinical
STK11 Q123* Different Alteration MTOR inhibitor Responsive CANCER Pre-clinical
STK11 Q123* Different Alteration PD1 inhibitor Resistant CANCER Early trials
STK11 Q123* Different Alteration Phenformin (Anti-diabetic) Responsive LUAD Pre-clinical
STK11 Q123* Different Alteration MEK inhibitor Responsive LUAD Pre-clinical
STK11 Q123* Different Alteration SRC inhibitor;PI3K/MEK inhibitor Responsive LUAD Pre-clinical
JAK2 C75F Different Alteration Ruxolitinib (JAK inhibitor) Responsive ALL Pre-clinical
FGFR2 E367Q Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 E367Q Different Alteration FGFR inhibitor Responsive BT Early trials
RET I625M Different Alteration Nintedanib (Pan-TK inhibitor) Responsive LUAD Case report
RET I625M Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Early trials
RET I625M Different Alteration RET inhibitor Responsive LUAD Pre-clinical
RET I625M Different Alteration Vandetanib (Pan-TK inhibitor) Responsive LUAD Early trials
RET I625M Different Alteration Sunitinib (Pan-TK inhibitor) Responsive LUAD Early trials
RET I625M Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive THCA Pre-clinical
RET I625M Different Alteration Vandetanib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET I625M Different Alteration Sunitinib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET I625M Different Alteration RET inhibitor Responsive TH Pre-clinical
PML P410A Different Alteration Volasertib (PLK1 inhibitor) Responsive AML Early trials
PML P410A Different Alteration Tretinoin (Retinoid) Responsive APML FDA guidelines
PML P410A Different Alteration Tretinoin;Arsenic Trioxide (Retinoid;Chemotherapy) Responsive AML FDA guidelines
SETD2 S618* Complete Match WEE1 inhibitor Responsive CANCER Pre-clinical
SETD2 S618* Different Alteration WEE1 inhibitor Responsive CANCER Pre-clinical
TP53 R306* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R306* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R306* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R306* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R306* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R306* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R306* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R306* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R306* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R306* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R306* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R306* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R306* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R306* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R306* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 A276P Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 A276P Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 A276P Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 A276P Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 A276P Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 A276P Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 A276P Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 A276P Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 A276P Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 A276P Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 A276P Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 A276P Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 A276P Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 A276P Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 A276P Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NF1 Q347* Different Mutation Vemurafenib (BRAF inhibitor) Resistant CM Pre-clinical
NF1 Q347* Different Mutation Everolimus (MTOR inhibitor) Responsive HNC Case report
NF1 Q347* Complete Match Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 Q347* Complete Match Vinblastine (Chemotherapy) Responsive G Early trials
NF1 Q347* Complete Match KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 Q347* Complete Match Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 Q347* Complete Match Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 Q347* Complete Match Retinoic Acid Resistant NB Pre-clinical
NF1 Q347* Complete Match Everolimus (MTOR inhibitor) Responsive NF Late trials
NF1 Q347* Complete Match Trametinib (MEK inhibitor) Responsive G Case report
NF1 Q347* Complete Match Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 Q347* Complete Match Nilotinib (BCR-ABL inhibitor) Responsive MPN, PLEN Pre-clinical
NF1 Q347* Complete Match MEK inhibitor Responsive MPN Pre-clinical
NF1 Q347* Complete Match Everolimus (MTOR inhibitor) Responsive HNC, SG Case report
NF1 Q347* Complete Match Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 Q347* Complete Match PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 Q347* Complete Match MEK inhibitor Responsive LK, G Pre-clinical
NF1 Q347* Complete Match Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 Q347* Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 Q347* Complete Match AURK inhibitor Responsive MPN Pre-clinical
NF1 Q347* Complete Match MTOR inhibitor Responsive LK, G, MPN Pre-clinical
NF1 Q347* Complete Match Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 Q347* Complete Match Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) Responsive HC Case report
NF1 Q347* Complete Match Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 Q347* Complete Match Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 Q347* Complete Match PD1 Ab inhibitor Responsive CM Early trials
NF1 Q347* Complete Match Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 Q347* Complete Match Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 Q347* Complete Match Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 Q347* Complete Match BRD4 inhibitor Responsive MPN Pre-clinical
NF1 Q347* Complete Match Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 Q347* Complete Match Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 Q347* Complete Match MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 Q347* Complete Match Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 Q347* Complete Match Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 Q347* Complete Match Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 Q347* Different Alteration MTOR inhibitor Responsive MPN, G, LK Pre-clinical
NF1 Q347* Different Alteration PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 Q347* Different Alteration Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 Q347* Different Alteration Trametinib (MEK inhibitor) Responsive G Case report
NF1 Q347* Different Alteration BRD4 inhibitor Responsive MPN Pre-clinical
NF1 Q347* Different Alteration Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 Q347* Different Alteration Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 Q347* Different Alteration Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 Q347* Different Alteration MEK inhibitor Responsive G, LK Pre-clinical
NF1 Q347* Different Alteration Vinblastine (Chemotherapy) Responsive G Early trials
NF1 Q347* Different Alteration Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 Q347* Different Alteration Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 Q347* Different Alteration Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 Q347* Different Alteration MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 Q347* Different Alteration Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 Q347* Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 Q347* Different Alteration Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 Q347* Different Alteration Everolimus (MTOR inhibitor) Responsive SG, HNC Case report
NF1 Q347* Different Alteration Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 Q347* Different Alteration Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 Q347* Different Alteration Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 Q347* Different Alteration Retinoic Acid Resistant NB Pre-clinical
NF1 Q347* Different Alteration Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 Q347* Different Alteration Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 Q347* Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive PLEN, MPN Pre-clinical
NF1 Q347* Different Alteration Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 Q347* Different Alteration Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 Q347* Different Alteration AURK inhibitor Responsive MPN Pre-clinical
NF1 Q347* Different Alteration Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 Q347* Different Alteration PD1 Ab inhibitor Responsive CM Early trials
NF1 Q347* Different Alteration MEK inhibitor Responsive MPN Pre-clinical
NF1 Q347* Different Alteration KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
EPHA3 splice_donor_variant Different Alteration EPHA3 inhibitor Responsive CANCER Pre-clinical
TP53 R282G Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R282G Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R282G Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R282G Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R282G Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R282G Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R282G Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R282G Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R282G Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R282G Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R282G Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R282G Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R282G Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R282G Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R282G Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PIK3CA K111N Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA K111N Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA K111N Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA K111N Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA K111N Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA K111N Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA K111N Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA K111N Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA K111N Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA K111N Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA K111N Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA K111N Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA K111N Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA K111N Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
PIK3CA M1004I Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA M1004I Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA M1004I Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA M1004I Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA M1004I Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA M1004I Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA M1004I Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA M1004I Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA M1004I Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA M1004I Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA M1004I Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA M1004I Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA M1004I Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA M1004I Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
EGFR R958R Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR R958R Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
TP53 Q167* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Q167* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Q167* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Q167* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Q167* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Q167* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Q167* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q167* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q167* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Q167* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Q167* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Q167* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q167* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Q167* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q167* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
CDH1 T379T Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
ROS1 T1735T Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 T1735T Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 T1735T Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 T1735T Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 T1735T Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
NOTCH1 A2036V Different Alteration Gamma secretase inhibitor Responsive ALL Pre-clinical
NOTCH1 A2036V Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
TP53 Y126N Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Y126N Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Y126N Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Y126N Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Y126N Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Y126N Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Y126N Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y126N Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Y126N Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Y126N Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Y126N Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Y126N Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y126N Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Y126N Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Y126N Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 V157F Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 V157F Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 V157F Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 V157F Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 V157F Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 V157F Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 V157F Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V157F Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V157F Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 V157F Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 V157F Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 V157F Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V157F Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 V157F Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V157F Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ROS1 P1743Q Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 P1743Q Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 P1743Q Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 P1743Q Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 P1743Q Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
NRG1 5-UTRSNV Different Alteration Lapatinib (ERBB2 inhibitor) Responsive LUAD Pre-clinical
NRG1 5-UTRSNV Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Case report
BRAF E433K Different Alteration Sorafenib (Pan-TK inhibitor) Responsive CM, LUAD, PRAD Pre-clinical
BRAF E433K Different Alteration MEK inhibitor Responsive LUAD, CM, PRAD Pre-clinical
BRAF E433K Different Alteration Selumetinib (MEK inhibitor) Responsive OV Case report
BRAF E433K Different Alteration BRAF inhibitor;MEK inhibitor Responsive LUAD Case report
NTRK3 R306P Different Alteration IGF1R inhibitor Responsive BRCA Pre-clinical
NTRK3 R306P Different Alteration PI3K pathway inhibitor Responsive BRCA Pre-clinical
NTRK3 R306P Different Alteration Midostaurin (Pan-TK inhibitor) Responsive BRCA Pre-clinical
NOTCH2 H151Y Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
KMT2A I3288I Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A I3288I Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A I3288I Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A I3288I Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A I3288I Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A I3288I Different Alteration DOT1L inhibitor Responsive AML Early trials
PDGFRA E556K Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive MDPS, MDS, ECL, HES FDA guidelines
PTPRD Q193* Complete Match IGF1R inhibitor Responsive S Case report
ALK E576Q Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK E576Q Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK E576Q Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK E576Q Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK E576Q Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK E576Q Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK E576Q Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK E576Q Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK E576Q Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK E576Q Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK E576Q Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK E576Q Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK E576Q Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK E576Q Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK E576Q Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK E576Q Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK E576Q Different Alteration ALK inhibitor Responsive COREAD Case report
ALK E576Q Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK E576Q Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
SETD2 S815* Complete Match WEE1 inhibitor Responsive CANCER Pre-clinical
SETD2 S815* Different Alteration WEE1 inhibitor Responsive CANCER Pre-clinical
CDKN1B splice_acceptor_variant Complete Match CDK2/4 inhibitor Responsive CANCER Pre-clinical
CDKN1B splice_acceptor_variant Different Alteration CDK2/4 inhibitor Responsive CANCER Pre-clinical
MSH2 R621* Complete Match PD1/PDL1 inhibitor Responsive UTH Early trials
MSH2 R621* Different Alteration PD1/PDL1 inhibitor Responsive UTH Early trials
KMT2A K1185K Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A K1185K Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A K1185K Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A K1185K Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A K1185K Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A K1185K Different Alteration DOT1L inhibitor Responsive AML Early trials
PIK3CA N1044Y Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA N1044Y Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA N1044Y Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA N1044Y Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA N1044Y Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA N1044Y Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA N1044Y Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA N1044Y Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA N1044Y Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA N1044Y Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA N1044Y Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA N1044Y Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA N1044Y Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA N1044Y Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
KRAS G12D Complete Match Panitumumab (EGFR mAb inhibitor) Resistant COREAD FDA guidelines
KRAS G12D Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD FDA guidelines
KRAS G12D Different Mutation Cetuximab (EGFR mAb inhibitor) No Responsive COREAD Late trials
KRAS G12D Complete Match MEK inhibitor Responsive ALL Pre-clinical
KRAS G12D Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Resistant GIST Case report
KRAS G12D Complete Match MEK inhibitor Responsive OV, CER, AML Pre-clinical
KRAS G12D Complete Match Abemaciclib (CDK4/6 inhibitor) Responsive L Early trials
KRAS G12D Complete Match MEK inhibitor;PI3K pathway inhibitor Responsive COREAD Pre-clinical
KRAS G12D Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD NCCN guidelines
KRAS G12D Complete Match Sorafenib;MEK inhibitor (Pan-TK inhibitor;MEK inhibitor) Responsive HC Early trials
KRAS G12D Complete Match EGFR inhibitor Resistant L NCCN guidelines
KRAS G12D Complete Match CDK4 inhibitor Responsive L Pre-clinical
KRAS G12D Complete Match Selumetinib (MEK inhibitor) Responsive NSCLC Early trials
KRAS G12D Complete Match BET inhibitor Responsive L Pre-clinical
KRAS G12D Complete Match Decitabine;BCL2 inhibitor (Chemotherapy;BCL2 inhibitor) Responsive OV Pre-clinical
KRAS G12D Complete Match FAK inhibitor Responsive L Pre-clinical
KRAS G12D Complete Match EGFR inhibitor Resistant NSCLC Pre-clinical
KRAS G12D Complete Match EZH2 inhibitor Resistant CANCER Pre-clinical
KRAS G12D Complete Match MEK inhibitor Responsive BT, L Early trials
KRAS G12D Complete Match MEK inhibitor;IGF1R inhibitor Responsive COREAD Pre-clinical
KRAS G12D Complete Match MTOR inhibitor;BH3 mimetics Responsive COREAD Pre-clinical
KRAS G12D Complete Match EGFR mAb inhibitor;MEK inhibitor Responsive COREAD Pre-clinical
KRAS G12D Complete Match pan-RAF inhibitor Responsive ED Case report
KRAS G12D Complete Match EGFR mAb inhibitor Resistant ST Pre-clinical
KRAS G12D Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive L Early trials
KRAS G12D Complete Match Selumetinib (MEK inhibitor) No Responsive L Early trials
KRAS G12D Complete Match CDK4/6 inhibitor;MEK inhibitor Responsive L Early trials
KRAS G12D Complete Match Trametinib;Ponatinib (MEK inhibitor;BCR-ABL inhibitor & Pan-TK inhibitor) Responsive LUAD Pre-clinical
KRAS G12D Complete Match Trastuzumab;Lapatinib (ERBB2 mAb inhibitor;ERBB2 inhibitor) Resistant COREAD Late trials
KRAS G12D Complete Match pan-RAF inhibitor Responsive L Early trials
KRAS G12D Complete Match JAK/TBK1/IKKε inhibitor Responsive L Pre-clinical
KRAS G12D Complete Match FAS inhibitor Responsive L Case report
KRAS G12D Complete Match HSP90 inhibitor Responsive L Pre-clinical
KRAS G12D Complete Match ERK inhibitor Responsive COREAD Pre-clinical
KRAS G12D Complete Match PI3K pathway inhibitor;MEK inhibitor No Responsive PA Early trials
KRAS G12D Complete Match MEK inhibitor;BCL-XL inhibitor Responsive COREAD Pre-clinical
KRAS G12D Complete Match Gemcitabine;MEK inhibitor (Chemotherapy;MEK inhibitor) Responsive PA Early trials
KRAS G12D Complete Match Panitumumab (EGFR mAb inhibitor) Resistant COREAD NCCN guidelines
KRAS G12D Complete Match PI3K pathway inhibitor Resistant ED Pre-clinical
KRAS G12D Complete Match CDK4/6 inhibitor;MEK inhibitor Responsive CESC Pre-clinical
KRAS G12D Different Alteration BRAF inhibitor;MEK inhibitor Resistant COREAD Case report
KRAS G12D Different Alteration BRAF inhibitor;EGFR mAb inhibitor Resistant COREAD Case report
SMARCA1 splice_acceptor_variant Complete Match EZH2 inhibitor Responsive CANCER Pre-clinical
BRAF R347L Different Alteration Sorafenib (Pan-TK inhibitor) Responsive CM, LUAD, PRAD Pre-clinical
BRAF R347L Different Alteration MEK inhibitor Responsive LUAD, CM, PRAD Pre-clinical
BRAF R347L Different Alteration Selumetinib (MEK inhibitor) Responsive OV Case report
BRAF R347L Different Alteration BRAF inhibitor;MEK inhibitor Responsive LUAD Case report
ALK G843R Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK G843R Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK G843R Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK G843R Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK G843R Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK G843R Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK G843R Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK G843R Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK G843R Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK G843R Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK G843R Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK G843R Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK G843R Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK G843R Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK G843R Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK G843R Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK G843R Different Alteration ALK inhibitor Responsive COREAD Case report
ALK G843R Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK G843R Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
MAP2K1 E203K Different Mutation MEK inhibitor Resistant CANCER Pre-clinical
MAP2K1 E203K Different Mutation novel MEK inhibitor Responsive CM Pre-clinical
MAP2K1 E203K Different Mutation MEK inhibitor Resistant CM Case report
MAP2K1 E203K Different Mutation ERK inhibitor Responsive CANCER Pre-clinical
MAP2K1 E203K Complete Match Vemurafenib (BRAF inhibitor) Resistant CM Case report
MAP2K1 E203K Different Mutation BRAF inhibitor Resistant CM Case report
MAP2K1 E203K Different Mutation Trametinib (MEK inhibitor) Responsive CANCER Pre-clinical
MAP2K1 E203K Different Mutation Panitumumab;Trametinib (EGFR mAb inhibitor;MEK inhibitor) Responsive COREAD Case report
MAP2K1 E203K Different Mutation Selumetinib (MEK inhibitor) Responsive OV Case report
MAP2K1 E203K Different Mutation BRAF inhibitor Resistant CM Early trials
MAP2K1 E203K Different Mutation ERK inhibitor Responsive CM Pre-clinical
MAP2K1 E203K Complete Match EGFR mAb inhibitor Resistant COREAD Case report
PTPRD E661* Complete Match IGF1R inhibitor Responsive S Case report
AKT3 S474F Different Alteration ATP competitive AKT inhibitor Responsive BRCA Pre-clinical
NTRK3 R582W Different Alteration IGF1R inhibitor Responsive BRCA Pre-clinical
NTRK3 R582W Different Alteration PI3K pathway inhibitor Responsive BRCA Pre-clinical
NTRK3 R582W Different Alteration Midostaurin (Pan-TK inhibitor) Responsive BRCA Pre-clinical
FGFR2 E471D), FGFR2 MUT* (D472Y Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 E471D), FGFR2 MUT* (D472Y Different Alteration FGFR inhibitor Responsive BT Early trials
TP53 Q136E Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Q136E Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Q136E Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Q136E Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Q136E Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Q136E Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Q136E Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q136E Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q136E Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Q136E Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Q136E Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Q136E Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q136E Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Q136E Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q136E Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C176* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C176* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C176* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C176* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C176* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C176* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C176* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C176* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C176* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C176* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C176* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C176* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C176* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C176* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C176* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ERBB4 G500E Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
BRAF L537S Different Alteration Sorafenib (Pan-TK inhibitor) Responsive CM, LUAD, PRAD Pre-clinical
BRAF L537S Different Alteration MEK inhibitor Responsive LUAD, CM, PRAD Pre-clinical
BRAF L537S Different Alteration Selumetinib (MEK inhibitor) Responsive OV Case report
BRAF L537S Different Alteration BRAF inhibitor;MEK inhibitor Responsive LUAD Case report
MTOR I1973F Different Mutation Sirolimus (MTOR inhibitor) Responsive CANCER Pre-clinical
MTOR I1973F Different Mutation Everolimus (MTOR inhibitor) Responsive R Case report
MTOR I1973F Complete Match Everolimus (MTOR inhibitor) Responsive AS, R, ST, AG Case report
MTOR I1973F Different Mutation Everolimus (MTOR inhibitor) Responsive BLCA Case report
MTOR I1973F Different Mutation Everolimus (MTOR inhibitor) Responsive ST Case report
MTOR I1973F Different Mutation Everolimus (MTOR inhibitor) Resistant THCA Case report
MTOR I1973F Different Mutation MTOR kinase inhibitor Responsive CANCER Pre-clinical
TP53 L130V Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 L130V Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 L130V Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 L130V Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 L130V Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 L130V Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 L130V Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L130V Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L130V Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 L130V Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 L130V Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 L130V Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L130V Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 L130V Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L130V Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ABL1 I347I Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
ABL1 I347I Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
ABL1 I347I Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
ABL1 I347I Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
ABL1 I347I Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
ABL1 I347I Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
TP53 E286K Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 E286K Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 E286K Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 E286K Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 E286K Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 E286K Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E286K Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E286K Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E286K Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 E286K Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 E286K Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 E286K Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E286K Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 E286K Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E286K Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
FGFR2 V633I Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 V633I Different Alteration FGFR inhibitor Responsive BT Early trials
ATR E1922* Complete Match Temozolomide (Chemotherapy) Responsive G Pre-clinical
ATR E1922* Complete Match Olaparib (PARP inhibitor) Responsive CANCER, OV Pre-clinical
ATR E1922* Different Alteration Olaparib (PARP inhibitor) Responsive OV, CANCER Pre-clinical
TP53 I255F Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 I255F Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 I255F Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 I255F Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 I255F Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 I255F Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 I255F Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 I255F Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 I255F Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 I255F Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 I255F Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 I255F Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 I255F Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 I255F Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 I255F Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 W91* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 W91* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 W91* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 W91* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 W91* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 W91* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 W91* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 W91* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 W91* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 W91* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 W91* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 W91* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 W91* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 W91* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 W91* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ABL1 D71N Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
ABL1 D71N Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
ABL1 D71N Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
ABL1 D71N Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
ABL1 D71N Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
ABL1 D71N Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
PIK3CA G106R Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA G106R Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA G106R Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA G106R Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA G106R Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA G106R Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA G106R Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA G106R Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA G106R Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA G106R Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA G106R Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA G106R Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA G106R Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA G106R Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
PDGFRA S1042S Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive MDPS, MDS, ECL, HES FDA guidelines
TP53 K132T Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 K132T Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 K132T Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 K132T Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 K132T Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 K132T Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 K132T Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 K132T Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 K132T Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 K132T Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 K132T Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 K132T Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 K132T Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 K132T Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 K132T Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
BAP1 T93A Complete Match EZH2 inhibitor Responsive MESO Pre-clinical
BAP1 T93A Complete Match PARP inhibitor Responsive R, CANCER Pre-clinical
BAP1 T93A Complete Match HDAC inhibitor Responsive CM Pre-clinical
BAP1 T93A Different Alteration PARP inhibitor Responsive CANCER, R Pre-clinical
BAP1 T93A Different Alteration EZH2 inhibitor Responsive MESO Pre-clinical
BAP1 T93A Different Alteration HDAC inhibitor Responsive CM Pre-clinical
KMT2A K255E Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A K255E Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A K255E Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A K255E Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A K255E Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A K255E Different Alteration DOT1L inhibitor Responsive AML Early trials
TP53 V157G Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 V157G Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 V157G Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 V157G Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 V157G Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 V157G Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 V157G Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V157G Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V157G Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 V157G Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 V157G Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 V157G Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V157G Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 V157G Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V157G Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
BRCA1 Q139* Complete Match Chemotherapy (PARP inhibitor;Chemotherapy) Responsive OV Early trials
BRCA1 Q139* Complete Match PARP inhibitor Responsive BRCA Early trials
BRCA1 Q139* Complete Match PARP inhibitor;Chemotherapy Responsive OV Early trials
BRCA1 Q139* Complete Match Rucaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 Q139* Complete Match Platinum Agent (Chemotherapy) Responsive BRCA Early trials
BRCA1 Q139* Complete Match WEE1 inhibitor Responsive CANCER Case report
BRCA1 Q139* Complete Match Platinum Agent (Chemotherapy) Responsive OV Late trials
BRCA1 Q139* Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
BRCA1 Q139* Complete Match Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) Responsive BRCA Early trials
BRCA1 Q139* Complete Match PARP inhibitor Responsive PA Case report
BRCA1 Q139* Complete Match Olaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 Q139* Different Alteration PARP inhibitor Responsive OV Pre-clinical
FBXW7 R465C Complete Match Steroid Responsive ALL Late trials
FBXW7 R465C Complete Match Tubulin inhibitor Resistant CANCER Pre-clinical
FBXW7 R465C Different Alteration Sirolimus (MTOR inhibitor) Responsive COREAD Pre-clinical
FBXW7 R465C Different Alteration Tubulin inhibitor Resistant CANCER Pre-clinical
KMT2A R442Q Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A R442Q Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A R442Q Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A R442Q Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A R442Q Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A R442Q Different Alteration DOT1L inhibitor Responsive AML Early trials
GATA3 W329* Complete Match Aromatase ihibitor Responsive BRCA Pre-clinical
RB1 R455* Different Alteration Palbociclib (CDK4/6 inhibitor) Responsive PRAD Pre-clinical
RB1 R455* Complete Match MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 R455* Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 R455* Complete Match HDAC inhibitor Responsive RB Pre-clinical
RB1 R455* Different Alteration MDM2/MDMX inhibitor Responsive RB Pre-clinical
RB1 R455* Different Alteration Cisplatin (Chemotherapy) Responsive BLCA Early trials
RB1 R455* Different Alteration HDAC inhibitor Responsive RB Pre-clinical
AKT3 E84K Different Alteration ATP competitive AKT inhibitor Responsive BRCA Pre-clinical
TP53 W91*), TP53 MUT (Y220S Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 W91*), TP53 MUT (Y220S Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 W91*), TP53 MUT (Y220S Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 W91*), TP53 MUT (Y220S Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 W91*), TP53 MUT (Y220S Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 W91*), TP53 MUT (Y220S Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 W91*), TP53 MUT (Y220S Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 W91*), TP53 MUT (Y220S Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 W91*), TP53 MUT (Y220S Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 W91*), TP53 MUT (Y220S Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 W91*), TP53 MUT (Y220S Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 W91*), TP53 MUT (Y220S Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 W91*), TP53 MUT (Y220S Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 W91*), TP53 MUT (Y220S Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 W91*), TP53 MUT (Y220S Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
KMT2A E1464* Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A E1464* Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A E1464* Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A E1464* Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A E1464* Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A E1464* Different Alteration DOT1L inhibitor Responsive AML Early trials
PDGFB R216C Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive DFS FDA guidelines
PLCG2 S225* Different Mutation Ibrutinib (BTK inhibitor) Resistant CLL Early trials
FAT1 S3029* Complete Match BET inhibitor Responsive HNSC Pre-clinical
FBXW7 G391D Complete Match Steroid Responsive ALL Late trials
FBXW7 G391D Complete Match Tubulin inhibitor Resistant CANCER Pre-clinical
FBXW7 G391D Different Alteration Sirolimus (MTOR inhibitor) Responsive COREAD Pre-clinical
FBXW7 G391D Different Alteration Tubulin inhibitor Resistant CANCER Pre-clinical
RET D547D Different Alteration Nintedanib (Pan-TK inhibitor) Responsive LUAD Case report
RET D547D Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Early trials
RET D547D Different Alteration RET inhibitor Responsive LUAD Pre-clinical
RET D547D Different Alteration Vandetanib (Pan-TK inhibitor) Responsive LUAD Early trials
RET D547D Different Alteration Sunitinib (Pan-TK inhibitor) Responsive LUAD Early trials
RET D547D Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive THCA Pre-clinical
RET D547D Different Alteration Vandetanib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET D547D Different Alteration Sunitinib (Pan-TK inhibitor) Responsive THCA Pre-clinical
RET D547D Different Alteration RET inhibitor Responsive TH Pre-clinical
SF3B1 N626D Different Mutation Spliceosome inhibitor Responsive CANCER Pre-clinical
JAK2 P429P Different Alteration Ruxolitinib (JAK inhibitor) Responsive ALL Pre-clinical
NOTCH1 G1376S Different Alteration Gamma secretase inhibitor Responsive ALL Pre-clinical
NOTCH1 G1376S Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
NF1 splice_acceptor_variant Different Mutation Vemurafenib (BRAF inhibitor) Resistant CM Pre-clinical
NF1 splice_acceptor_variant Different Mutation Everolimus (MTOR inhibitor) Responsive HNC Case report
NF1 splice_acceptor_variant Complete Match Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 splice_acceptor_variant Complete Match Vinblastine (Chemotherapy) Responsive G Early trials
NF1 splice_acceptor_variant Complete Match KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Complete Match Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Complete Match Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 splice_acceptor_variant Complete Match Retinoic Acid Resistant NB Pre-clinical
NF1 splice_acceptor_variant Complete Match Everolimus (MTOR inhibitor) Responsive NF Late trials
NF1 splice_acceptor_variant Complete Match Trametinib (MEK inhibitor) Responsive G Case report
NF1 splice_acceptor_variant Complete Match Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Complete Match Nilotinib (BCR-ABL inhibitor) Responsive MPN, PLEN Pre-clinical
NF1 splice_acceptor_variant Complete Match MEK inhibitor Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Complete Match Everolimus (MTOR inhibitor) Responsive HNC, SG Case report
NF1 splice_acceptor_variant Complete Match Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 splice_acceptor_variant Complete Match PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 splice_acceptor_variant Complete Match MEK inhibitor Responsive LK, G Pre-clinical
NF1 splice_acceptor_variant Complete Match Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 splice_acceptor_variant Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 splice_acceptor_variant Complete Match AURK inhibitor Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Complete Match MTOR inhibitor Responsive LK, G, MPN Pre-clinical
NF1 splice_acceptor_variant Complete Match Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 splice_acceptor_variant Complete Match Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) Responsive HC Case report
NF1 splice_acceptor_variant Complete Match Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 splice_acceptor_variant Complete Match Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 splice_acceptor_variant Complete Match PD1 Ab inhibitor Responsive CM Early trials
NF1 splice_acceptor_variant Complete Match Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 splice_acceptor_variant Complete Match Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 splice_acceptor_variant Complete Match Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 splice_acceptor_variant Complete Match BRD4 inhibitor Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Complete Match Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 splice_acceptor_variant Complete Match Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 splice_acceptor_variant Complete Match MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Complete Match Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 splice_acceptor_variant Complete Match Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 splice_acceptor_variant Complete Match Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 splice_acceptor_variant Different Alteration MTOR inhibitor Responsive MPN, G, LK Pre-clinical
NF1 splice_acceptor_variant Different Alteration PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 splice_acceptor_variant Different Alteration Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 splice_acceptor_variant Different Alteration Trametinib (MEK inhibitor) Responsive G Case report
NF1 splice_acceptor_variant Different Alteration BRD4 inhibitor Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Different Alteration Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 splice_acceptor_variant Different Alteration Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 splice_acceptor_variant Different Alteration Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 splice_acceptor_variant Different Alteration MEK inhibitor Responsive G, LK Pre-clinical
NF1 splice_acceptor_variant Different Alteration Vinblastine (Chemotherapy) Responsive G Early trials
NF1 splice_acceptor_variant Different Alteration Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Different Alteration Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 splice_acceptor_variant Different Alteration Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 splice_acceptor_variant Different Alteration MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Different Alteration Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 splice_acceptor_variant Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 splice_acceptor_variant Different Alteration Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Different Alteration Everolimus (MTOR inhibitor) Responsive SG, HNC Case report
NF1 splice_acceptor_variant Different Alteration Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 splice_acceptor_variant Different Alteration Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 splice_acceptor_variant Different Alteration Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 splice_acceptor_variant Different Alteration Retinoic Acid Resistant NB Pre-clinical
NF1 splice_acceptor_variant Different Alteration Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 splice_acceptor_variant Different Alteration Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 splice_acceptor_variant Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive PLEN, MPN Pre-clinical
NF1 splice_acceptor_variant Different Alteration Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 splice_acceptor_variant Different Alteration Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 splice_acceptor_variant Different Alteration AURK inhibitor Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Different Alteration Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 splice_acceptor_variant Different Alteration PD1 Ab inhibitor Responsive CM Early trials
NF1 splice_acceptor_variant Different Alteration MEK inhibitor Responsive MPN Pre-clinical
NF1 splice_acceptor_variant Different Alteration KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
TP53 E286Q Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 E286Q Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 E286Q Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 E286Q Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 E286Q Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 E286Q Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E286Q Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E286Q Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E286Q Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 E286Q Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 E286Q Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 E286Q Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E286Q Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 E286Q Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E286Q Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NOTCH1 E1903D Different Alteration Gamma secretase inhibitor Responsive ALL Pre-clinical
NOTCH1 E1903D Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
PIK3CA P104L Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA P104L Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA P104L Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA P104L Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA P104L Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA P104L Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA P104L Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA P104L Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA P104L Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA P104L Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA P104L Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA P104L Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA P104L Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA P104L Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
FGFR2 H545Q Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 H545Q Different Alteration FGFR inhibitor Responsive BT Early trials
ROS1 V2068V Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 V2068V Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 V2068V Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 V2068V Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 V2068V Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
NOTCH2 S1110F Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
ARID1A Q1631* Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A Q1631* Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A Q1631* Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A Q1631* Complete Match ATR inhibitor Responsive CANCER Pre-clinical
NOTCH2 R2400* Complete Match Mk-0752 (Gamma secretase inhibitor) Responsive ALL, AML, BRCA Early trials
NOTCH2 R2400* Complete Match OMP-59R5 (NOTCH2 inhibitor) Responsive SOLID Early trials
NOTCH2 R2400* Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
CDH1 K668* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
PIK3CA E81K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E81K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E81K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E81K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E81K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E81K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E81K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E81K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E81K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E81K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E81K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E81K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E81K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E81K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
BRD4 M1073I Different Alteration BET inhibitor Responsive NMC Case report
HIF1A Q730* Different Alteration Sunitinib (Pan-TK inhibitor) Responsive R Pre-clinical
TP53 E258* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 E258* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 E258* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 E258* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 E258* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 E258* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 E258* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E258* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 E258* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 E258* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 E258* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 E258* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E258* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 E258* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 E258* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
MET D414N Different Alteration Crizotinib (ALK inhibitor) Responsive G Case report
PDGFRA 3-UTRSNV Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive MDPS, MDS, ECL, HES FDA guidelines
CDK12 E488* Complete Match PARP inhibitor Responsive OV Pre-clinical
CDK12 E488* Different Alteration PARP inhibitor Responsive OV Pre-clinical
NTRK1 L96V Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Case report
NTRK1 L96V Different Alteration Pan-TKR inhibitor Responsive CANCER Early trials
NTRK1 L96V Different Alteration Pan-TK inhibitor Responsive LUAD Pre-clinical
NTRK1 L96V Different Alteration Pan-TK inhibitor Responsive COREAD Case report
ARID1A R1335* Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A R1335* Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A R1335* Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A R1335* Complete Match ATR inhibitor Responsive CANCER Pre-clinical
TP53 Q192* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Q192* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Q192* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Q192* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Q192* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Q192* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Q192* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q192* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q192* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Q192* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Q192* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Q192* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q192* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Q192* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q192* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ALK V597G Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK V597G Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK V597G Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK V597G Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK V597G Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK V597G Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK V597G Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK V597G Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK V597G Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK V597G Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK V597G Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK V597G Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK V597G Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK V597G Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK V597G Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK V597G Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK V597G Different Alteration ALK inhibitor Responsive COREAD Case report
ALK V597G Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK V597G Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
PIK3CA E542K), PIK3CA MUT (E726K Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E542K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E542K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E542K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E542K), PIK3CA MUT (E726K Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E542K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E542K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E542K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E542K), PIK3CA MUT (E726K Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E542K), PIK3CA MUT (E726K Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E542K), PIK3CA MUT (E726K Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E542K), PIK3CA MUT (E726K Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E542K), PIK3CA MUT (E726K Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E542K), PIK3CA MUT (E726K Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
NF1 S2601* Different Mutation Vemurafenib (BRAF inhibitor) Resistant CM Pre-clinical
NF1 S2601* Different Mutation Everolimus (MTOR inhibitor) Responsive HNC Case report
NF1 S2601* Complete Match Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 S2601* Complete Match Vinblastine (Chemotherapy) Responsive G Early trials
NF1 S2601* Complete Match KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
NF1 S2601* Complete Match Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 S2601* Complete Match Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 S2601* Complete Match Retinoic Acid Resistant NB Pre-clinical
NF1 S2601* Complete Match Everolimus (MTOR inhibitor) Responsive NF Late trials
NF1 S2601* Complete Match Trametinib (MEK inhibitor) Responsive G Case report
NF1 S2601* Complete Match Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 S2601* Complete Match Nilotinib (BCR-ABL inhibitor) Responsive MPN, PLEN Pre-clinical
NF1 S2601* Complete Match MEK inhibitor Responsive MPN Pre-clinical
NF1 S2601* Complete Match Everolimus (MTOR inhibitor) Responsive HNC, SG Case report
NF1 S2601* Complete Match Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 S2601* Complete Match PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 S2601* Complete Match MEK inhibitor Responsive LK, G Pre-clinical
NF1 S2601* Complete Match Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 S2601* Complete Match Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 S2601* Complete Match AURK inhibitor Responsive MPN Pre-clinical
NF1 S2601* Complete Match MTOR inhibitor Responsive LK, G, MPN Pre-clinical
NF1 S2601* Complete Match Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 S2601* Complete Match Everolimus;Pazopanib (MTOR inhibitor;VEGFR inhibitor) Responsive HC Case report
NF1 S2601* Complete Match Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 S2601* Complete Match Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 S2601* Complete Match PD1 Ab inhibitor Responsive CM Early trials
NF1 S2601* Complete Match Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 S2601* Complete Match Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 S2601* Complete Match Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 S2601* Complete Match BRD4 inhibitor Responsive MPN Pre-clinical
NF1 S2601* Complete Match Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 S2601* Complete Match Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 S2601* Complete Match MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 S2601* Complete Match Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 S2601* Complete Match Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 S2601* Complete Match Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 S2601* Different Alteration MTOR inhibitor Responsive MPN, G, LK Pre-clinical
NF1 S2601* Different Alteration PLX3397 (Pan-TK inhibitor) Responsive PLEN Pre-clinical
NF1 S2601* Different Alteration Erlotinib (EGFR inhibitor) Resistant L Pre-clinical
NF1 S2601* Different Alteration Trametinib (MEK inhibitor) Responsive G Case report
NF1 S2601* Different Alteration BRD4 inhibitor Responsive MPN Pre-clinical
NF1 S2601* Different Alteration Trametinib (MEK inhibitor) No Responsive OS Case report
NF1 S2601* Different Alteration Cediranib (ALK inhibitor) No Responsive PLEN Early trials
NF1 S2601* Different Alteration Bevacizumab (VEGFR mAb inhibitor) Responsive G Case report
NF1 S2601* Different Alteration MEK inhibitor Responsive G, LK Pre-clinical
NF1 S2601* Different Alteration Vinblastine (Chemotherapy) Responsive G Early trials
NF1 S2601* Different Alteration Sorafenib;Sirolimus (Pan-TK inhibitor;MTOR inhibitor) Responsive MPN Pre-clinical
NF1 S2601* Different Alteration Everolimus;Bevacizumab (MTOR inhibitor;VEGFR mAb inhibitor) No Responsive MPN Early trials
NF1 S2601* Different Alteration Dasatinib (BCR-ABL inhibitor) Resistant L Pre-clinical
NF1 S2601* Different Alteration MTOR inhibitor;HSP90 inhibitor Responsive MPN Pre-clinical
NF1 S2601* Different Alteration Sirolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) Responsive G Case report
NF1 S2601* Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive PLEN Early trials
NF1 S2601* Different Alteration Tamoxifen (Hormonal therapy) Responsive MPN Pre-clinical
NF1 S2601* Different Alteration Everolimus (MTOR inhibitor) Responsive SG, HNC Case report
NF1 S2601* Different Alteration Pan-RAF inhibitor;MEK inhibitor Responsive CM Pre-clinical
NF1 S2601* Different Alteration Tipifarnib (Farnesyltransferase inhibitor) No Responsive PLEN Early trials
NF1 S2601* Different Alteration Selumetinib (MEK inhibitor) Responsive PLEN Early trials
NF1 S2601* Different Alteration Retinoic Acid Resistant NB Pre-clinical
NF1 S2601* Different Alteration Everolimus (MTOR inhibitor) No Responsive MPN Early trials
NF1 S2601* Different Alteration Sirolimus (MTOR inhibitor) Responsive PLEN Early trials
NF1 S2601* Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive PLEN, MPN Pre-clinical
NF1 S2601* Different Alteration Vinblastine;Nilotinib (Chemotherapy;BCR-ABL inhibitor) Responsive G Case report
NF1 S2601* Different Alteration Trametinib (MEK inhibitor) Responsive CM Pre-clinical
NF1 S2601* Different Alteration AURK inhibitor Responsive MPN Pre-clinical
NF1 S2601* Different Alteration Everolimus;Erlotinib (MTOR inhibitor;EGFR inhibitor) No Responsive G Case report
NF1 S2601* Different Alteration PD1 Ab inhibitor Responsive CM Early trials
NF1 S2601* Different Alteration MEK inhibitor Responsive MPN Pre-clinical
NF1 S2601* Different Alteration KIT inhibitor;MTOR inhibitor Responsive MPN Pre-clinical
TP53 L257R Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 L257R Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 L257R Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 L257R Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 L257R Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 L257R Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 L257R Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L257R Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 L257R Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 L257R Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 L257R Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 L257R Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L257R Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 L257R Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 L257R Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NRG1 A547T Different Alteration Lapatinib (ERBB2 inhibitor) Responsive LUAD Pre-clinical
NRG1 A547T Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Case report
TP53 D281E Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 D281E Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 D281E Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 D281E Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 D281E Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 D281E Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 D281E Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 D281E Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 D281E Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 D281E Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 D281E Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 D281E Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 D281E Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 D281E Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 D281E Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PTEN F258L), PTEN MUT (F258Y Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN F258L), PTEN MUT (F258Y Complete Match Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN F258L), PTEN MUT (F258Y Complete Match BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN F258L), PTEN MUT (F258Y Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN F258L), PTEN MUT (F258Y Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN F258L), PTEN MUT (F258Y Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN F258L), PTEN MUT (F258Y Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN F258L), PTEN MUT (F258Y Complete Match PARP inhibitor Responsive ED Case report
PTEN F258L), PTEN MUT (F258Y Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN F258L), PTEN MUT (F258Y Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN F258L), PTEN MUT (F258Y Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN F258L), PTEN MUT (F258Y Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN F258L), PTEN MUT (F258Y Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN F258L), PTEN MUT (F258Y Complete Match AKT inhibitor Responsive PA Case report
PTEN F258L), PTEN MUT (F258Y Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN F258L), PTEN MUT (F258Y Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN F258L), PTEN MUT (F258Y Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN F258L), PTEN MUT (F258Y Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN F258L), PTEN MUT (F258Y Different Alteration PARP inhibitor Responsive ED Case report
PTEN F258L), PTEN MUT (F258Y Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN F258L), PTEN MUT (F258Y Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN F258L), PTEN MUT (F258Y Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN F258L), PTEN MUT (F258Y Different Alteration AKT inhibitor Responsive PA Case report
PTEN F258L), PTEN MUT (F258Y Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN F258L), PTEN MUT (F258Y Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
RAF1 E607Q Different Alteration Sorafenib (Pan-TK inhibitor) Responsive PRAD Pre-clinical
RAF1 E607Q Different Alteration Pan-RAF inhibitor Responsive PRAD Pre-clinical
RAF1 E607Q Different Alteration U0126 (MEK inhibitor) Responsive PRAD Pre-clinical
BRD4 intron_variant Different Alteration BET inhibitor Responsive NMC Case report
TP53 R280K Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 R280K Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 R280K Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 R280K Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 R280K Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 R280K Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 R280K Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R280K Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 R280K Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 R280K Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 R280K Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 R280K Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R280K Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 R280K Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 R280K Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
SF3B1 K666N Complete Match Spliceosome inhibitor Responsive CANCER Pre-clinical
PIK3CA E545K), PIK3CA MUT (C420R Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA E545K), PIK3CA MUT (C420R Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA E545K), PIK3CA MUT (C420R Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA E545K), PIK3CA MUT (C420R Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA E545K), PIK3CA MUT (C420R Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA E545K), PIK3CA MUT (C420R Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA E545K), PIK3CA MUT (C420R Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA E545K), PIK3CA MUT (C420R Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA E545K), PIK3CA MUT (C420R Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA E545K), PIK3CA MUT (C420R Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA E545K), PIK3CA MUT (C420R Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA E545K), PIK3CA MUT (C420R Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA E545K), PIK3CA MUT (C420R Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA E545K), PIK3CA MUT (C420R Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
NTRK3 L827F Different Alteration IGF1R inhibitor Responsive BRCA Pre-clinical
NTRK3 L827F Different Alteration PI3K pathway inhibitor Responsive BRCA Pre-clinical
NTRK3 L827F Different Alteration Midostaurin (Pan-TK inhibitor) Responsive BRCA Pre-clinical
SMARCA4 splice_acceptor_variant Complete Match EZH2 inhibitor Responsive OVRT Case report
SMARCA4 splice_acceptor_variant Complete Match AURKA inhibitor Responsive NSCLC Pre-clinical
SMARCA4 splice_acceptor_variant Complete Match EZH2 inhibitor Responsive OV Case report
SMARCA4 splice_acceptor_variant Different Alteration EZH2 inhibitor Responsive OVRT Case report
SMARCA4 splice_acceptor_variant Different Alteration EZH2 inhibitor Responsive OV Case report
ERBB4 5-UTRSNV Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
BCR D904N Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
BCR D904N Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
BCR D904N Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR D904N Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR D904N Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
BCR D904N Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
PTEN L140* Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN L140* Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN L140* Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN L140* Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN L140* Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN L140* Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN L140* Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN L140* Complete Match PARP inhibitor Responsive ED Case report
PTEN L140* Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN L140* Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN L140* Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN L140* Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN L140* Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN L140* Complete Match AKT inhibitor Responsive PA Case report
PTEN L140* Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN L140* Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN L140* Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN L140* Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN L140* Different Alteration PARP inhibitor Responsive ED Case report
PTEN L140* Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN L140* Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN L140* Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN L140* Different Alteration AKT inhibitor Responsive PA Case report
PTEN L140* Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN L140* Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
CDK12 Y246* Complete Match PARP inhibitor Responsive OV Pre-clinical
CDK12 Y246* Different Alteration PARP inhibitor Responsive OV Pre-clinical
TP53 T253S), TP53 MUT (Q331* Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 T253S), TP53 MUT (Q331* Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 T253S), TP53 MUT (Q331* Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 T253S), TP53 MUT (Q331* Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 T253S), TP53 MUT (Q331* Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 T253S), TP53 MUT (Q331* Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 T253S), TP53 MUT (Q331* Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 T253S), TP53 MUT (Q331* Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 T253S), TP53 MUT (Q331* Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 T253S), TP53 MUT (Q331* Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 T253S), TP53 MUT (Q331* Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 T253S), TP53 MUT (Q331* Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 T253S), TP53 MUT (Q331* Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 T253S), TP53 MUT (Q331* Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 T253S), TP53 MUT (Q331* Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
BCR I57I Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
BCR I57I Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
BCR I57I Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR I57I Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR I57I Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
BCR I57I Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
PTEN D92E Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN D92E Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN D92E Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN D92E Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN D92E Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN D92E Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN D92E Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN D92E Complete Match PARP inhibitor Responsive ED Case report
PTEN D92E Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN D92E Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN D92E Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN D92E Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN D92E Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN D92E Complete Match AKT inhibitor Responsive PA Case report
PTEN D92E Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN D92E Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN D92E Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN D92E Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN D92E Different Alteration PARP inhibitor Responsive ED Case report
PTEN D92E Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN D92E Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN D92E Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN D92E Different Alteration AKT inhibitor Responsive PA Case report
PTEN D92E Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN D92E Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PIK3CA N345H Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA N345H Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA N345H Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA N345H Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA N345H Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA N345H Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA N345H Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA N345H Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA N345H Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA N345H Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA N345H Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA N345H Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA N345H Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA N345H Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
FGFR3 3-UTRSNV Different Alteration FGFR inhibitor Responsive BLCA Case report
FGFR3 3-UTRSNV Different Alteration FGFR inhibitor Responsive G Early trials
FGFR3 3-UTRSNV Different Alteration FGFR inhibitor Responsive NSCLC Pre-clinical
PTEN A126G Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN A126G Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN A126G Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN A126G Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN A126G Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN A126G Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN A126G Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN A126G Complete Match PARP inhibitor Responsive ED Case report
PTEN A126G Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN A126G Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN A126G Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN A126G Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN A126G Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN A126G Complete Match AKT inhibitor Responsive PA Case report
PTEN A126G Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN A126G Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN A126G Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN A126G Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN A126G Different Alteration PARP inhibitor Responsive ED Case report
PTEN A126G Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN A126G Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN A126G Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN A126G Different Alteration AKT inhibitor Responsive PA Case report
PTEN A126G Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN A126G Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
EGFR intron_variant Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR intron_variant Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
EGFR E928V Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR E928V Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
TP53 V157D Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 V157D Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 V157D Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 V157D Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 V157D Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 V157D Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 V157D Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V157D Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 V157D Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 V157D Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 V157D Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 V157D Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V157D Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 V157D Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 V157D Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
RAF1 R354W Different Alteration Sorafenib (Pan-TK inhibitor) Responsive PRAD Pre-clinical
RAF1 R354W Different Alteration Pan-RAF inhibitor Responsive PRAD Pre-clinical
RAF1 R354W Different Alteration U0126 (MEK inhibitor) Responsive PRAD Pre-clinical
NOTCH2 C1342C Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
GATA3 K347* Complete Match Aromatase ihibitor Responsive BRCA Pre-clinical
PIK3CA P366R Different Mutation BRAF inhibitor Resistant CM Case report
PIK3CA P366R Complete Match PI3K pathway inhibitor Responsive BLCA, HNC Case report
PIK3CA P366R Complete Match PI3K pathway inhibitor Responsive HNSC Case report
PIK3CA P366R Complete Match PI3K pathway inhibitor Responsive G, THCA Pre-clinical
PIK3CA P366R Complete Match Everolimus;Trastuzumab;Chemotherapy (MTOR inhibitor;ERBB2 mAb inhibitor;Chemotherapy) Responsive BRCA Late trials
PIK3CA P366R Complete Match PI3K pathway inhibitor Responsive COREAD Pre-clinical
PIK3CA P366R Complete Match PI3K pathway inhibitor Responsive ED, OV, CESC Early trials
PIK3CA P366R Complete Match PI3K pathway inhibitor Responsive BRCA Late trials
PIK3CA P366R Complete Match PIK3CA inhibitor Responsive BRCA Early trials
PIK3CA P366R Complete Match PIK3CA inhibitor Responsive ST Case report
PIK3CA P366R Complete Match AKT inhibitor Responsive BRCA Early trials
PIK3CA P366R Complete Match PI3K pathway inhibitor Responsive;Responsive L Pre-clinical;Case report
PIK3CA P366R Complete Match Cetuximab (EGFR mAb inhibitor) Resistant COREAD Late trials
PIK3CA P366R Different Alteration PI3K pathway inhibitor Resistant BRCA Pre-clinical
EGFR A289V Different Alteration Cetuximab (EGFR mAb inhibitor) Responsive COREAD FDA guidelines
EGFR A289V Different Alteration Panitumumab (EGFR mAb inhibitor) Resistant COREAD FDA guidelines
EGFR A289V Different Mutation Rindopepimut (Vaccine) Responsive GB Late trials
EGFR A289V Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR A289V Different Mutation Gefitinib (EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR A289V Different Mutation HSP90 inhibitor Responsive L Early trials
EGFR A289V Different Mutation Afatinib;Cetuximab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) Responsive L Early trials
EGFR A289V Different Mutation MEK inhibitor Responsive L Pre-clinical
EGFR A289V Different Mutation EGFR TK inhibitor Responsive L Late trials
EGFR A289V Different Mutation Erlotinib (EGFR inhibitor) Responsive NSCLC NCCN guidelines
EGFR A289V Different Mutation Osimertinib (EGFR inhibitor) Resistant L Early trials
EGFR A289V Different Mutation EGFR-TKI's (EGFR inhibitor) Resistant L Late trials
EGFR A289V Different Mutation HSP90 inhibitor Responsive L Case report
EGFR A289V Different Mutation EGFR inhibitor Resistant L Late trials
EGFR A289V Different Mutation Poziotinib (EGFR inhibitor) Responsive L Early trials
EGFR A289V Different Mutation Osimertinib (EGFR inhibitor) Responsive L Pre-clinical
EGFR A289V Different Mutation HSP90 inhibitor (HSP90 inhibitor) Responsive L Early trials
EGFR A289V Complete Match Erlotinib (EGFR inhibitor) Responsive G Pre-clinical
EGFR A289V Different Mutation Erlotinib (EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR A289V Different Mutation Osimertinib (EGFR inhibitor) Responsive L Early trials
EGFR A289V Different Mutation Rociletinib (EGFR inhibitor) Resistant LUAD Case report
EGFR A289V Different Mutation Panitumumab (EGFR mAb inhibitor) Responsive COREAD Case report
EGFR A289V Different Mutation novel EGFR mAb inhibitor Responsive COREAD Early trials
EGFR A289V Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
EGFR A289V Different Mutation Cetuximab;Sirolimus (EGFR mAb inhibitor;MTOR inhibitor) Responsive HNC Case report
EGFR A289V Different Mutation Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR A289V Different Mutation Gefitinib (EGFR inhibitor) No Responsive HNC Case report
EGFR A289V Different Mutation EGFR inhibitor Responsive L Early trials
EGFR A289V Different Mutation Erlotinib (EGFR inhibitor) Resistant L NCCN/CAP guidelines
EGFR A289V Different Mutation Osimertinib (EGFR inhibitor) Responsive NSCLC FDA guidelines
EGFR A289V Different Mutation EGFR inhibitor Responsive NSCLC Late trials
EGFR A289V Different Mutation Afatinib;Nimotuzumab (ERBB2 & EGFR inhibitor;EGFR mAb inhibitor) Responsive L Early trials
EGFR A289V Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Resistant L NCCN/CAP guidelines
EGFR A289V Different Mutation Erlotinib (EGFR inhibitor) Responsive L Early trials
EGFR A289V Different Mutation Afatinib (ERBB2 & EGFR inhibitor) Responsive L Late trials
EGFR A289V Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Pre-clinical
EGFR A289V Different Mutation Erlotinib (EGFR inhibitor) No Responsive L Case report
EGFR A289V Different Mutation Lapatinib (ERBB2 inhibitor) Responsive ED Case report
EGFR A289V Different Mutation EGFR inhibitor No Responsive G Early trials
EGFR A289V Different Mutation EGFR inhibitor Resistant NSCLC Case report
EGFR A289V Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
EGFR A289V Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant;Resistant COREAD Pre-clinical;Case report
EGFR A289V Different Mutation Cetuximab (EGFR mAb inhibitor) Responsive HNC Case report
EGFR A289V Different Alteration Gefitinib (EGFR inhibitor) Responsive ED Late trials
EGFR A289V Different Alteration Gefitinib (EGFR inhibitor) No Responsive HNC Early trials
EGFR A289V Different Alteration EGFR inhibitor Responsive HNSC Case report
EGFR A289V Different Alteration EGFR inhibitor No Responsive G Early trials
EGFR A289V Different Alteration Erlotinib (EGFR inhibitor) No Responsive L Early trials
EGFR A289V Different Alteration EGFR mAb inhibitor Responsive COREAD Late trials
EGFR A289V Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR A289V Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
CDH1 R335* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
TP53 H179Q Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 H179Q Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 H179Q Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 H179Q Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 H179Q Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 H179Q Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 H179Q Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H179Q Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 H179Q Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 H179Q Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 H179Q Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 H179Q Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H179Q Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 H179Q Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 H179Q Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
BRCA1 Q1408* Complete Match Chemotherapy (PARP inhibitor;Chemotherapy) Responsive OV Early trials
BRCA1 Q1408* Complete Match PARP inhibitor Responsive BRCA Early trials
BRCA1 Q1408* Complete Match PARP inhibitor;Chemotherapy Responsive OV Early trials
BRCA1 Q1408* Complete Match Rucaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 Q1408* Complete Match Platinum Agent (Chemotherapy) Responsive BRCA Early trials
BRCA1 Q1408* Complete Match WEE1 inhibitor Responsive CANCER Case report
BRCA1 Q1408* Complete Match Platinum Agent (Chemotherapy) Responsive OV Late trials
BRCA1 Q1408* Complete Match Olaparib (PARP inhibitor) Responsive PRAD Early trials
BRCA1 Q1408* Complete Match Veliparib;Cisplatin (PARP inhibitor;Chemotherapy) Responsive BRCA Early trials
BRCA1 Q1408* Complete Match PARP inhibitor Responsive PA Case report
BRCA1 Q1408* Complete Match Olaparib (PARP inhibitor) Responsive OV FDA guidelines
BRCA1 Q1408* Different Alteration PARP inhibitor Responsive OV Pre-clinical
CDH1 E512* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
HRAS G12D Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive CER Pre-clinical
HRAS G12D Complete Match MEK inhibitor +/- MTOR inhibitor Responsive AML Pre-clinical
HRAS G12D Complete Match MTOR inhibitor Responsive CESC Pre-clinical
HRAS G12D Complete Match Tipifarnib (Farnesyltransferase inhibitor) Responsive CANCER Early trials
ERCC2 splice_donor_variant Complete Match Cisplatin (Chemotherapy) Responsive BLCA Early trials
ERCC2 splice_donor_variant Complete Match PD1/PDL1 inhibitor Responsive UTH Early trials
ERCC2 splice_donor_variant Different Alteration PD1/PDL1 inhibitor Responsive UTH Early trials
NTRK1 D209H Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Case report
NTRK1 D209H Different Alteration Pan-TKR inhibitor Responsive CANCER Early trials
NTRK1 D209H Different Alteration Pan-TK inhibitor Responsive LUAD Pre-clinical
NTRK1 D209H Different Alteration Pan-TK inhibitor Responsive COREAD Case report
TP53 C242G Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C242G Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C242G Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C242G Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C242G Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C242G Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C242G Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C242G Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C242G Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C242G Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C242G Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C242G Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C242G Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C242G Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C242G Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
EGFR E97Q Different Alteration Erlotinib (EGFR inhibitor) Responsive L Case report
EGFR E97Q Different Alteration Erlotinib (EGFR inhibitor) Responsive NSCLC Case report
ROS1 L1872V Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 L1872V Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 L1872V Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 L1872V Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 L1872V Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
TP53 M169I Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 M169I Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 M169I Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 M169I Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 M169I Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 M169I Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 M169I Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 M169I Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 M169I Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 M169I Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 M169I Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 M169I Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 M169I Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 M169I Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 M169I Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
NOTCH2 D1306N), NOTCH2 MUT* (3-UTRSNV Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
NRG1 R18Q Different Alteration Lapatinib (ERBB2 inhibitor) Responsive LUAD Pre-clinical
NRG1 R18Q Different Alteration Afatinib (ERBB2 & EGFR inhibitor) Responsive LUAD Case report
ABL1 3-UTRSNV Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
ABL1 3-UTRSNV Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
ABL1 3-UTRSNV Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
ABL1 3-UTRSNV Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
ABL1 3-UTRSNV Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
ABL1 3-UTRSNV Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
FGFR2 H254Y Different Alteration FGFR inhibitor Responsive COREAD Early trials
FGFR2 H254Y Different Alteration FGFR inhibitor Responsive BT Early trials
CDKN1B Q141*), CDKN1B MUT (Q20* Complete Match CDK2/4 inhibitor Responsive CANCER Pre-clinical
CDKN1B Q141*), CDKN1B MUT (Q20* Different Alteration CDK2/4 inhibitor Responsive CANCER Pre-clinical
NOTCH2 L1690L Different Alteration Gamma secretase inhibitor Responsive BRCA Pre-clinical
TP53 S127Y Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 S127Y Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 S127Y Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 S127Y Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 S127Y Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 S127Y Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 S127Y Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 S127Y Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 S127Y Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 S127Y Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 S127Y Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 S127Y Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 S127Y Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 S127Y Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 S127Y Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C275Y Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 C275Y Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 C275Y Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 C275Y Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 C275Y Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 C275Y Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 C275Y Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C275Y Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 C275Y Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 C275Y Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 C275Y Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 C275Y Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C275Y Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 C275Y Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 C275Y Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
PTEN Q149* Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN Q149* Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN Q149* Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN Q149* Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN Q149* Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN Q149* Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN Q149* Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN Q149* Complete Match PARP inhibitor Responsive ED Case report
PTEN Q149* Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN Q149* Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN Q149* Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN Q149* Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN Q149* Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN Q149* Complete Match AKT inhibitor Responsive PA Case report
PTEN Q149* Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN Q149* Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN Q149* Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN Q149* Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN Q149* Different Alteration PARP inhibitor Responsive ED Case report
PTEN Q149* Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN Q149* Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN Q149* Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN Q149* Different Alteration AKT inhibitor Responsive PA Case report
PTEN Q149* Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN Q149* Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN Y76* Different Mutation Cetuximab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN Y76* Different Mutation Panitumumab (EGFR mAb inhibitor) Resistant COREAD Case report
PTEN Y76* Different Mutation BYL719 (PIK3CA inhibitor) Resistant BRCA Case report
PTEN Y76* Complete Match ATM inhibitor Responsive BRCA Pre-clinical
PTEN Y76* Complete Match PI3K pathway inhibitor Responsive BRCA, ED, TH, CANCER, L, G, OV Pre-clinical
PTEN Y76* Complete Match EGFR mAb inhibitor Resistant COREAD Late trials
PTEN Y76* Complete Match Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN Y76* Complete Match PARP inhibitor Responsive ED Case report
PTEN Y76* Complete Match PD1 Ab inhibitor Resistant CM Early trials
PTEN Y76* Complete Match PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN Y76* Complete Match Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN Y76* Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
PTEN Y76* Complete Match PIK3CB inhibitor Responsive PRAD Case report
PTEN Y76* Complete Match AKT inhibitor Responsive PA Case report
PTEN Y76* Complete Match MTOR inhibitor No Responsive ED Early trials
PTEN Y76* Different Alteration PI3K pathway inhibitor Responsive L, BRCA, CANCER, G, ED, TH, OV Pre-clinical
PTEN Y76* Different Alteration Everolimus (MTOR inhibitor) Responsive PRAD Early trials
PTEN Y76* Different Alteration Sirolimus (MTOR inhibitor) Responsive CANCER Early trials
PTEN Y76* Different Alteration PARP inhibitor Responsive ED Case report
PTEN Y76* Different Alteration PIK3CB inhibitor Responsive PRAD Case report
PTEN Y76* Different Alteration EGFR mAb inhibitor Resistant COREAD Late trials
PTEN Y76* Different Alteration MTOR inhibitor No Responsive ED Early trials
PTEN Y76* Different Alteration AKT inhibitor Responsive PA Case report
PTEN Y76* Different Alteration PI3K pathway inhibitor;AR antagonist Responsive PRAD Pre-clinical
PTEN Y76* Different Alteration PI3K pathway inhibitor;MEK inhibitor Responsive OV Pre-clinical
IDH1 R132H Complete Match Venetoclax (BCL2 inhibitor) Responsive AML Early trials
IDH1 R132H Complete Match IDH1 inhibitor Responsive AML Early trials
IDH1 R132H Complete Match AG-120 (IDH1 inhibitor) Responsive G Early trials
IDH1 R132H Complete Match Dasatinib (BCR-ABL inhibitor) Responsive CH Early trials
IDH1 R132H Complete Match Ivosidenib (IDH1 inhibitor) Responsive AML Early trials
IDH1 R132H Complete Match BCL2 inhibitor Responsive AML Pre-clinical
IDH1 R132H Complete Match BCL2 inhibitor (BCL2 inhibitor) Responsive AML Pre-clinical
IDH1 R132H Complete Match Dasatinib (BCR-ABL inhibitor) Responsive BT Pre-clinical
IDH1 R132H Complete Match PARP inhibitor Responsive CANCER Pre-clinical
BRAF A569D Different Alteration Sorafenib (Pan-TK inhibitor) Responsive CM, LUAD, PRAD Pre-clinical
BRAF A569D Different Alteration MEK inhibitor Responsive LUAD, CM, PRAD Pre-clinical
BRAF A569D Different Alteration Selumetinib (MEK inhibitor) Responsive OV Case report
BRAF A569D Different Alteration BRAF inhibitor;MEK inhibitor Responsive LUAD Case report
HRAS G12C Complete Match PI3K pathway inhibitor;MEK inhibitor Responsive CER Pre-clinical
HRAS G12C Complete Match MEK inhibitor +/- MTOR inhibitor Responsive AML Pre-clinical
HRAS G12C Complete Match MTOR inhibitor Responsive CESC Pre-clinical
HRAS G12C Complete Match Tipifarnib (Farnesyltransferase inhibitor) Responsive CANCER Early trials
CDH1 Q673* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
KMT2A I1401F Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A I1401F Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A I1401F Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A I1401F Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A I1401F Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A I1401F Different Alteration DOT1L inhibitor Responsive AML Early trials
BAP1 Y627* Complete Match EZH2 inhibitor Responsive MESO Pre-clinical
BAP1 Y627* Complete Match PARP inhibitor Responsive R, CANCER Pre-clinical
BAP1 Y627* Complete Match HDAC inhibitor Responsive CM Pre-clinical
BAP1 Y627* Different Alteration PARP inhibitor Responsive CANCER, R Pre-clinical
BAP1 Y627* Different Alteration EZH2 inhibitor Responsive MESO Pre-clinical
BAP1 Y627* Different Alteration HDAC inhibitor Responsive CM Pre-clinical
BCR 3-UTRSNV Different Alteration Ponatinib (BCR-ABL inhibitor & Pan-TK inhibitor) Responsive CML, ALL FDA guidelines
BCR 3-UTRSNV Different Alteration Imatinib (BCR-ABL inhibitor & KIT inhibitor) Responsive ALL, CML FDA guidelines
BCR 3-UTRSNV Different Alteration Nilotinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR 3-UTRSNV Different Alteration Bosutinib (BCR-ABL inhibitor) Responsive CML FDA guidelines
BCR 3-UTRSNV Different Alteration Dasatinib;Venetoclax (BCR-ABL inhibitor;BCL2 inhibitor) Responsive ALL Pre-clinical
BCR 3-UTRSNV Different Alteration Dasatinib (BCR-ABL inhibitor) Responsive ALL, CML FDA guidelines
KMT2A 3-UTRSNV Different Alteration EPZ-5676 (DOT1L inhibitor) Responsive ALL, MDS, AML Early trials
KMT2A 3-UTRSNV Different Alteration BET inhibitor Responsive ALL Pre-clinical
KMT2A 3-UTRSNV Different Alteration BET inhibitor Responsive AML Pre-clinical
KMT2A 3-UTRSNV Different Alteration Daunorubicin (Chemotherapy) Responsive AML FDA guidelines
KMT2A 3-UTRSNV Different Alteration Belinostat (HDAC inhibitor) Responsive AML Early trials
KMT2A 3-UTRSNV Different Alteration DOT1L inhibitor Responsive AML Early trials
TP53 Q136P Different Mutation HSP90 inhibitor Responsive CANCER Pre-clinical
TP53 Q136P Complete Match Decitabine (Chemotherapy) Responsive AML, MDPS Early trials
TP53 Q136P Complete Match Abemaciclib (CDK4/6 inhibitor) Resistant BRCA Early trials
TP53 Q136P Different Mutation HDM2 inhibitor Responsive AML Early trials
TP53 Q136P Complete Match Cisplatin (Chemotherapy) Resistant FGCT, MGCT Early trials
TP53 Q136P Complete Match AZD6738 (ATR inhibitor) Responsive BCL Early trials
TP53 Q136P Complete Match Gemcitabine (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q136P Complete Match Mitomycin C (Chemotherapy) Responsive BLCA Pre-clinical
TP53 Q136P Complete Match WEE1 inhibitor Responsive HNC Pre-clinical
TP53 Q136P Complete Match MDM2 inhibitor Resistant LIP Early trials
TP53 Q136P Complete Match Doxorubicin (Anthracycline antitumor antibiotic) Responsive BLCA Pre-clinical
TP53 Q136P Complete Match Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q136P Complete Match WEE1 inhibitor Responsive OV Early trials
TP53 Q136P Different Alteration Pramlintide (Amylin analogue) Responsive THYM Pre-clinical
TP53 Q136P Different Alteration AZD6738 (ATR inhibitor) Responsive BCL Early trials
ALK E296K Different Alteration ALK inhibitor;SRC inhibitor Responsive LUAD Pre-clinical
ALK E296K Different Alteration Crizotinib (ALK inhibitor) Responsive GB, LY Early trials
ALK E296K Different Alteration Lorlatinib (ALK&ROS1 inhibitor) Responsive NSCLC Early trials
ALK E296K Different Alteration Crizotinib (ALK inhibitor) Responsive THCA, IM Case report
ALK E296K Different Alteration HSP90 inhibitor Responsive LUAD Early trials
ALK E296K Different Alteration Ceritinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK E296K Different Alteration Ceritinib (ALK inhibitor) Responsive IM, COREAD Case report
ALK E296K Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD, NSCLC FDA guidelines
ALK E296K Different Alteration Brigatinib (Pan-TK inhibitor) Responsive NSCLC FDA guidelines
ALK E296K Different Alteration Entrictinib (Pan-TK inhibitor) Responsive COREAD Case report
ALK E296K Different Alteration Alectinib (ALK inhibitor) Responsive LUAD FDA guidelines
ALK E296K Different Alteration HSP90 inhibitor (HSP90 inhibitor) Responsive LUAD Early trials
ALK E296K Different Alteration ALK inhibitor;IGF1R inhibitor Responsive LUAD Pre-clinical
ALK E296K Different Alteration ALK inhibitor;MEK inhibitor Responsive LUAD Pre-clinical
ALK E296K Different Alteration novel ALK inhibitor Responsive LUAD Early trials
ALK E296K Different Alteration Ceritinib (ALK inhibitor) Responsive HEMATO Early trials
ALK E296K Different Alteration ALK inhibitor Responsive COREAD Case report
ALK E296K Different Alteration Alectinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ALK E296K Different Alteration MEK inhibitor (ALK inhibitor;MEK inhibitor) Responsive LUAD Pre-clinical
ROS1 splice_acceptor_variant Different Alteration Crizotinib (ALK inhibitor) Responsive IM Case report
ROS1 splice_acceptor_variant Different Alteration Crizotinib (ALK inhibitor) Responsive NSCLC FDA guidelines
ROS1 splice_acceptor_variant Different Alteration Cabozantinib (Pan-kinase inhibitor) Responsive LUAD Case report
ROS1 splice_acceptor_variant Different Alteration HSP90 inhibitor Responsive LUAD Pre-clinical
ROS1 splice_acceptor_variant Different Alteration Crizotinib (ALK inhibitor) Responsive LUAD Early trials
ERBB4 H190Y Different Alteration Lapatinib;Afatinib (ERBB2 inhibitor;ERBB2 & EGFR inhibitor) Responsive LUAD Pre-clinical
SMARCA1 S324* Complete Match EZH2 inhibitor Responsive CANCER Pre-clinical
CDH1 Q129* Complete Match Bicalutamide (AR inhibitor) Responsive BRCA Pre-clinical
ARID1A splice_acceptor_variant Complete Match EZH2 inhibitor Responsive OV Pre-clinical
ARID1A splice_acceptor_variant Complete Match PD1 inhibitor Responsive OV Pre-clinical
ARID1A splice_acceptor_variant Complete Match PARP inhibitor Responsive CANCER Pre-clinical
ARID1A splice_acceptor_variant Complete Match ATR inhibitor Responsive CANCER Pre-clinical
Variation Gene Transcript Protein Alteration Consequence Tumour Driver Oncogenic Classification
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Cancer Genome Interpreter (CGI)
Drug-Gene Interactions help

Druggable categories in the cohort

No meaningful categories found

Drug-Gene Interactions

Focus the search to a gene of interest:

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Gene Interaction Source Interaction Types Drug Claim Primary Name Drug Name ChEMBL ID
TP53 CKB CTX-1
TP53 CKB Gemcitabine GEMCITABINE CHEMBL888
TP53 ClearityFoundationClinicalTrial GRANISETRON GRANISETRON CHEMBL289469
TP53 CKB epirubicin EPIRUBICIN CHEMBL417
TP53 NCI TOPICAL CORTICOSTEROIDS
TP53 CKB Trametinib TRAMETINIB CHEMBL2103875
TP53 TALC vaccine AD.P53-DC
TP53 CKB Cisplatin
TP53 NCI YONDELIS YONDELIS CHEMBL297812
TP53 CKB Doxorubicin DOXORUBICIN CHEMBL53463
TP53 CGI MK-1775 AZD-1775 CHEMBL1976040
TP53 CKB Paclitaxel PACLITAXEL CHEMBL428647
TP53 NCI ZINC CHLORIDE ZINC CHLORIDE CHEMBL1200679
TP53 CKB PD-0325901 PD-0325901 CHEMBL507361
TP53 CKB PK11007
TP53 CKB Temozolomide TEMOZOLOMIDE CHEMBL810
TP53 CKB TC-A2317
TP53 CKB NU6027 CHEMBL303958 CHEMBL303958
TP53 NCI DAB
TP53 CKB IGF-1R antibody
TP53 CKB PT2399
TP53 CKB Ifosfamide IFOSFAMIDE CHEMBL1024
TP53 CIViC SELUMETINIB (AZD6244) SELUMETINIB CHEMBL1614701
TP53 CKB EGFR antibody
TP53 NCI IL-12 PROXYPHYLLINE CHEMBL37390
TP53 NCI METHIMAZOLE METHIMAZOLE CHEMBL1515
TP53 CKB Cytarabine CYTARABINE CHEMBL803
TP53 TTD activator CURAXIN CBLC102
TP53 CGI Pramlintide PRAMLINTIDE CHEMBL2103758
TP53 CIViC CAPECITABINE CAPECITABINE CHEMBL1773
TP53 CKB Docetaxel DOCETAXEL CHEMBL92
TP53 NCI PROPYLTHIOURACIL PROPYLTHIOURACIL CHEMBL1518
TP53 CKB Ibrutinib IBRUTINIB CHEMBL1873475
TP53 CKB INC280 CAPMATINIB CHEMBL3188267
TP53 CKB Prodigiosin PRODIGIOSIN CHEMBL275787
TP53 CKB CGM097
TP53 CKB SRA737
TP53 NCI PUROMYCIN PUROMYCIN CHEMBL469912
TP53 CKB ABT-737 CHEMBL376408 CHEMBL376408
TP53 CKB Crizotinib CRIZOTINIB CHEMBL601719
TP53 NCI RAPAMYCIN SIROLIMUS CHEMBL413
TP53 CKB AZD6738 AZD-6738 CHEMBL3545178
TP53 CKB p53-SLP vaccine
TP53 CKB Irinotecan IRINOTECAN CHEMBL481
TP53 NCI TRIETHYLENETHIOPHOSPHORAMIDE THIOTEPA CHEMBL671
TP53 NCI GARLIC GARLIC CHEMBL2108463
TP53 CKB MK-8745
TP53 CIViC AMGMDS3
TP53 CKB Erlotinib ERLOTINIB CHEMBL553
TP53 CKB Pembrolizumab PEMBROLIZUMAB CHEMBL3137343
TP53 NCI VEGF BEVACIZUMAB CHEMBL1201583
TP53 CKB AMG 232
TP53 CKB BEZ235 DACTOLISIB CHEMBL1879463
TP53 CKB Vemurafenib VEMURAFENIB CHEMBL1229517
TP53 CKB YW3-56
TP53 CKB SAR405838
TP53 CGI Cisplatin
TP53 CGI Abemaciclib ABEMACICLIB CHEMBL3301610
TP53 CKB PF-00477736 PF-00477736 CHEMBL3545137
TP53 CKB AMG 900 AMG-900 CHEMBL2140408
TP53 CKB GSK2830371
TP53 CKB unspecified IGF-1R antibody
TP53 NCI DNA VACCINE
TP53 CKB Doxil
TP53 CKB AMG 337 AMG-337 CHEMBL3545212
TP53 CKB AZD6482 AZD-6482 CHEMBL2165191
TP53 CGI Decitabine DECITABINE CHEMBL1201129
TP53 CIViC NUTLIN-3A
TP53 CKB Bevacizumab BEVACIZUMAB CHEMBL1201583
TP53 NCI TRIFLUOPERAZINE TRIFLUOPERAZINE CHEMBL422
TP53 CIViC TAMOXIFEN TAMOXIFEN CHEMBL83
TP53 CIViC DOCETAXEL DOCETAXEL CHEMBL92
TP53 CKB ERBB3 antibody
TP53 CKB Tanespimycin TANESPIMYCIN CHEMBL109480
TP53 CKB JQ1
TP53 CKB R547 RG-547 CHEMBL384304
TP53 CKB Selumetinib SELUMETINIB CHEMBL1614701
TP53 CGI AZD6738 AZD-6738 CHEMBL3545178
TP53 CKB Olaparib OLAPARIB CHEMBL521686
TP53 NCI TIRAPAZAMINE TIRAPAZAMINE CHEMBL50882
TP53 CIViC CISPLATIN
TP53 CKB Trifluridine TRIFLURIDINE CHEMBL1129
TP53 CIViC DOXORUBICIN DOXORUBICIN CHEMBL53463
TP53 CKB Epirubicin EPIRUBICIN CHEMBL417
TP53 CKB Radiotherapy
TP53 CKB NSC59984
TP53 CKB Duvelisib DUVELISIB CHEMBL3039502
TP53 CIViC CETUXIMAB CETUXIMAB CHEMBL1201577
TP53 NCI MPA MYCOPHENOLIC ACID CHEMBL866
TP53 CKB Vorinostat VORINOSTAT CHEMBL98
TP53 CKB Alvespimycin ALVESPIMYCIN CHEMBL383824
TP53 CKB Daunoxome
TP53 CKB APR-246
TP53 CKB Cyclophosphamide CYCLOPHOSPHAMIDE CHEMBL88
TP53 CKB APG-115
TP53 CKB AZD2461
TP53 CKB unspecified ERBB3 antibody
TP53 CKB MI-63
TP53 CIViC CHEMOTHERAPY
TP53 CKB AZD5363 AZD-5363 CHEMBL2178577
TP53 CKB MLN0128 INK-128 CHEMBL3545056
TP53 CKB Nutlin-3a
TP53 CKB Dasatinib DASATINIB CHEMBL1421
TP53 CKB Carboplatin CARBOPLATIN CHEMBL1351
TP53 NCI CISPLATIN
TP53 CKB Sapanisertib INK-128 CHEMBL3545056
TP53 CKB NSC319726
TP53 CKB p28
TP53 CKB Dabrafenib DABRAFENIB CHEMBL2028663
TP53 NCI CAROTENOID
TP53 CKB DS-7423 DS-7423 CHEMBL3545248
TP53 CKB ONC201
TP53 CKB Camptosar
TP53 CKB Ganetespib GANETESPIB CHEMBL2103879
TP53 CKB RO6839921
TP53 CKB LY3009120 LY-3009120 CHEMBL3545195
TP53 CKB Ad.p53-DC vaccine
TP53 CKB Flourouracil
TP53 NCI RITUXIMAB RITUXIMAB CHEMBL1201576
TP53 NCI SAPONIN
TP53 NCI MCP-1
TP53 NCI DES DIETHYLSTILBESTROL CHEMBL411
TP53 NCI R-FLURBIPROFEN TARENFLURBIL CHEMBL190083
TP53 NCI HALOPERIDOL HALOPERIDOL CHEMBL54
TP53 CKB PF-04217903 PF-04217903 CHEMBL2001019
TP53 CKB Oxaliplatin OXALIPLATIN CHEMBL414804
TP53 CKB Serdemetan
TP53 TALC inhibitor BORTEZOMIB BORTEZOMIB CHEMBL325041
TP53 CKB CPUY201112
TP53 CKB MVAp53
TP53 CKB Pazopanib PAZOPANIB CHEMBL477772
TP53 CGI Mitomycin C MITOMYCIN CHEMBL105
TP53 NCI FAS LIGAND RIZATRIPTAN CHEMBL905
TP53 CKB thioureidobutyronitrile
TP53 CKB Alpelisib ALPELISIB CHEMBL2396661
TP53 CKB Nutlin-3 NUTLIN-3 CHEMBL191334
TP53 CKB Abemaciclib ABEMACICLIB CHEMBL3301610
TP53 CKB Navitoclax NAVITOCLAX CHEMBL443684
TP53 CKB PF-06463922 LORLATINIB CHEMBL3286830
TP53 CIViC ADJUVANT CHEMOTHERAPY
TP53 CKB ALRN-6924
TP53 CKB GDC-0425 RG-7602 CHEMBL3545007
TP53 CKB SP600125 SP-600125 CHEMBL1725279
TP53 CKB MPI-0479605 HEMICHOLINIUM-3 CHEMBL268697
TP53 CKB Avastin BEVACIZUMAB CHEMBL1201583
TP53 NCI VESNARINONE VESNARINONE CHEMBL17423
TP53 CKB EMD 1214063 Tepotinib CHEMBL3402762
TP53 CKB Pimasertib PIMASERTIB CHEMBL2107832
TP53 CKB RG7112
TP53 CKB LB-100
TP53 CKB
TP53 CKB AZD7762 AZD-7762 CHEMBL2041933
TP53 CKB HDM201
TP53 NCI L-744,832 CHEMBL1221512 CHEMBL1221512
TP53 CKB PF-05212384 GEDATOLISIB CHEMBL592445
TP53 CKB Etoposide ETOPOSIDE CHEMBL44657
TP53 CKB ReACp53
TP53 NCI ENALAPRIL ENALAPRIL CHEMBL578
TP53 NCI SELECTIVE ESTROGEN RECEPTOR MODULATORS
TP53 CKB unspecified EGFR antibody
TP53 CKB MK-1775 AZD-1775 CHEMBL1976040
TP53 CGI Doxorubicin DOXORUBICIN CHEMBL53463
TP53 CKB LY411575 CHEMBL392068 CHEMBL392068
TP53 CKB PI-3065
TP53 CGI Gemcitabine GEMCITABINE CHEMBL888
TP53 NCI METHYLPREDNISOLONE METHYLPREDNISOLONE CHEMBL650
TP53 CIViC CARBOPLATIN CARBOPLATIN CHEMBL1351
TP53 CKB Demcizumab DEMCIZUMAB CHEMBL2109384
TP53 CIViC RG7112
TP53 CKB Sirolimus SIROLIMUS CHEMBL413
TP53 NCI INTERFERON ALPHA-2B INTERFERON ALFA-2B CHEMBL1201558
TP53 CKB Daunorubicin DAUNORUBICIN CHEMBL178
TP53 NCI GOSSYPOL GOSSYPOL CHEMBL51483
TP53 CKB BLZ945
TP53 CKB PHA-680632 PHA-680632 CHEMBL363160
TP53 CKB Topotecan TOPOTECAN CHEMBL84
TP53 CKB 7RH
TP53 CKB LGX818 ENCORAFENIB CHEMBL3301612
TP53 NCI INOSITOL INOSITOL CHEMBL1222251
TP53 TALC vaccine EP-2101
TP53 CIViC OXALIPLATIN OXALIPLATIN CHEMBL414804
TP53 CKB ABT-263 NAVITOCLAX CHEMBL443684
TP53 CKB MK-8242
TP53 CKB VX-970 VX-970 CHEMBL3545202
TP53 CKB CP-31398
TP53 NCI URSODEOXYCHOLIC ACID URSODIOL CHEMBL1551
TP53 CKB Ad5CMV-p53 gene
TP53 NCI PACLITAXEL PACLITAXEL CHEMBL428647
TP53 CKB CEP-8983
TP53 CKB Panitumumab PANITUMUMAB CHEMBL1201827
TP53 NCI STREPTONIGRIN STREPTONIGRIN CHEMBL11417
TP53 CKB Seliciclib SELICICLIB CHEMBL14762
TP53 CKB PD0166285
Oncogenic Pathways help
Oncogenic Pathways
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Oncogenic Pathways
Interaction Networks help
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Select a gene to see its drug/phenotype/protein interactions

Reactome Pathways help

All significant pathways (p<0.05) in the selected cohort are presented in the Voronoi interactive plot, with colour intensity representing the number of patients affected
Click here to show visualisation below or here to open the visualisation in a new window

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PCA Gene Expression Correlation
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Scatterplot of Two main Principal Components

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Scatterplot of Three main Principal Components

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There are patients available from the BCN Biobank that match the selected/a subset of the criteria. Explore the data available for these patients using our Cohort Browser.

Researchers can request samples from BCNB website to support their research activities.

*Based on your filtering criteria you can view the number of available patients and associated samples in BCNB

In order to apply for samples, please use the BCNB Request System to submit an Expression of interest (EOI) form.

If you require further details please contact us at tissue.bank@breastcancernow.org

Patient ID Age at Diagnosis Sex Race Definition Menopausal Status Cancer Type ER PR HER2 Event Event Site Survival Status Survival Time (years) Subtype Genetic Ancestry hidden
TCGA-A7-A13G 79 female White Primary solid Tumor postmenopausal IDC positive positive negative new primary skin alive 1.97 LumA European TCGA.A7.A13G.01A.11R.A13Q.07
TCGA-A7-A13G 79 female White Solid Tissue Normal postmenopausal IDC positive positive negative new primary skin alive 1.97 LumA European TCGA.A7.A13G.11A.51R.A13Q.07
TCGA-E2-A10B 67 female White Primary solid Tumor postmenopausal IDC positive positive equivocal new primary lung alive 2.05 LumA European TCGA.E2.A10B.01A.11R.A10J.07
TCGA-E2-A14R 62 female White Primary solid Tumor postmenopausal IDC negative negative negative new primary endometrial alive 2.31 Basal European TCGA.E2.A14R.01A.11R.A115.07
TCGA-A7-A13H 61 female White Primary solid Tumor postmenopausal ILC positive positive equivocal new primary skin alive 2.46 NA European TCGA.A7.A13H.01A.11R.A22K.07
TCGA-AR-A5QM 62 female White Primary solid Tumor postmenopausal ILC positive positive equivocal new primary melanoma alive 6.11 LumA European TCGA.AR.A5QM.01A.11R.A27Q.07
TCGA-B6-A2IU 62 female White Primary solid Tumor indeterminate ILC positive positive not evaluated new primary lung alive 14.17 LumA European TCGA.B6.A2IU.01A.32R.A18M.07
TCGA-B6-A0WZ 50 female Black or African American Primary solid Tumor indeterminate IDC positive positive not evaluated new primary bone alive 17.23 LumA African_admix TCGA.B6.A0WZ.01A.11R.A109.07
TCGA-BH-A18V 48 female White Primary solid Tumor not available IDC negative negative negative metastasis intramammary node dead 4.26 Basal European TCGA.BH.A18V.01A.11R.A12D.07
TCGA-BH-A18V 48 female White Solid Tissue Normal not available IDC negative negative negative metastasis intramammary node dead 4.26 Basal European TCGA.BH.A18V.11A.52R.A12D.07
TCGA-E9-A1NI 51 female White Primary solid Tumor postmenopausal IDC/ILC positive positive negative NA NA alive NA NA European TCGA.E9.A1NI.01A.11R.A14D.07
TCGA-PL-A8LV 54 female Black or African American Primary solid Tumor unknown medullary carcinoma not evaluated not evaluated not evaluated NA NA alive NA Basal African TCGA.PL.A8LV.01A.21R.A41B.07
TCGA-A2-A25D 90 female White Primary solid Tumor postmenopausal ILC positive negative negative NA NA alive NA LumA European TCGA.A2.A25D.01A.12R.A16F.07
TCGA-A8-A06N 66 female not available Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive NA LumB European TCGA.A8.A06N.01A.11R.A00Z.07
TCGA-A8-A081 80 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive NA LumB European TCGA.A8.A081.01A.11R.A00Z.07
TCGA-A8-A083 67 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive NA LumA European TCGA.A8.A083.01A.21R.A00Z.07
TCGA-A8-A08H 66 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive NA Normal European TCGA.A8.A08H.01A.21R.A00Z.07
TCGA-A8-A090 74 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive NA LumA European TCGA.A8.A090.01A.11R.A00Z.07
TCGA-A8-A094 75 female not available Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive NA Her2 European TCGA.A8.A094.01A.11R.A00Z.07
TCGA-A8-A096 73 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive NA LumB European TCGA.A8.A096.01A.11R.A00Z.07
TCGA-A8-A09G 79 female not available Primary solid Tumor postmenopausal IDC positive negative positive NA NA alive NA Her2 European TCGA.A8.A09G.01A.21R.A00Z.07
TCGA-A8-A09Z 83 female not available Primary solid Tumor postmenopausal ILC positive negative negative NA NA alive NA LumB European TCGA.A8.A09Z.01A.11R.A00Z.07
TCGA-AC-A3W6 90 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive NA NA European TCGA.AC.A3W6.01A.12R.A22K.07
TCGA-C8-A12K 80 female Asian Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive NA Basal East Asian TCGA.C8.A12K.01A.21R.A115.07
TCGA-C8-A12T 43 female Asian Primary solid Tumor premenopausal IDC positive positive positive NA NA alive NA Her2 East Asian TCGA.C8.A12T.01A.11R.A115.07
TCGA-C8-A133 65 female White Primary solid Tumor postmenopausal ductal/mucinous positive positive not evaluated NA NA alive NA NA South Asian_admix TCGA.C8.A133.01A.32R.A12D.07
TCGA-C8-A26Y 90 female Asian Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive NA Her2 East Asian TCGA.C8.A26Y.01A.11R.A16F.07
TCGA-D8-A1JK 90 female White Primary solid Tumor postmenopausal IDC negative positive negative NA NA alive NA Basal European TCGA.D8.A1JK.01A.11R.A13Q.07
TCGA-LL-A6FP 90 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive NA LumA European TCGA.LL.A6FP.01A.11R.A31O.07
TCGA-AC-A7VC 56 female White Primary solid Tumor postmenopausal metaplastic carcinoma negative negative negative NA NA alive NA Basal European TCGA.AC.A7VC.01A.11R.A352.07
TCGA-C8-A275 56 female Asian Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive NA Her2 East Asian TCGA.C8.A275.01A.21R.A16F.07
TCGA-AN-A0AM 56 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 0.01 LumB European TCGA.AN.A0AM.01A.11R.A034.07
TCGA-C8-A1HJ 53 female Asian Primary solid Tumor perimenopausal IDC negative negative negative NA NA alive 0.01 Basal East Asian TCGA.C8.A1HJ.01A.11R.A13Q.07
TCGA-E9-A1N4 41 female White Primary solid Tumor premenopausal IDC/ILC positive positive positive NA NA alive 0.01 NA European TCGA.E9.A1N4.01A.11R.A14M.07
TCGA-E9-A1N4 41 female White Solid Tissue Normal premenopausal IDC/ILC positive positive positive NA NA alive 0.01 NA European TCGA.E9.A1N4.11A.33R.A14M.07
TCGA-PL-A8LX 35 female Black or African American Primary solid Tumor premenopausal IDC not evaluated not evaluated not evaluated metastasis bone|liver alive 0.01 LumA African TCGA.PL.A8LX.01A.11R.A41B.07
TCGA-C8-A273 29 female Asian Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.02 LumA East Asian TCGA.C8.A273.01A.11R.A16F.07
TCGA-AN-A041 29 female White Primary solid Tumor premenopausal IDC positive negative positive NA NA alive 0.02 LumA European_admix TCGA.AN.A041.01A.11R.A034.07
TCGA-C8-A12W 49 female Asian Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.02 LumB East Asian TCGA.C8.A12W.01A.11R.A115.07
TCGA-C8-A138 54 female Asian Primary solid Tumor postmenopausal IDC positive negative equivocal NA NA alive 0.02 Her2 East Asian TCGA.C8.A138.01A.11R.A115.07
TCGA-C8-A1HK 53 female Asian Primary solid Tumor perimenopausal IDC negative negative positive NA NA alive 0.02 Her2 East Asian TCGA.C8.A1HK.01A.21R.A13Q.07
TCGA-C8-A26W 58 female Asian Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 0.02 LumB East Asian TCGA.C8.A26W.01A.11R.A16F.07
TCGA-C8-A3M8 68 female Asian Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 0.02 LumB East Asian TCGA.C8.A3M8.01A.11R.A213.07
TCGA-AR-A0U0 73 female White Primary solid Tumor postmenopausal IDC negative negative not evaluated NA NA alive 0.02 Basal European TCGA.AR.A0U0.01A.11R.A109.07
TCGA-C8-A8HP 59 female Asian Primary solid Tumor postmenopausal metaplastic carcinoma negative negative positive NA NA alive 0.02 Her2 East Asian TCGA.C8.A8HP.01A.11R.A36F.07
TCGA-E9-A5FL 65 female White Primary solid Tumor postmenopausal metaplastic carcinoma negative negative negative NA NA alive 0.02 Basal European TCGA.E9.A5FL.01A.11R.A27Q.07
TCGA-PL-A8LY 30 female Black or African American Primary solid Tumor premenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.02 Normal African TCGA.PL.A8LY.01A.11R.A41B.07
TCGA-AC-A5XU 74 female Black or African American Primary solid Tumor not available IDC positive positive negative NA NA alive 0.02 LumA African TCGA.AC.A5XU.01A.11R.A28M.07
TCGA-AN-A0XP 69 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.02 LumA European TCGA.AN.A0XP.01A.11R.A109.07
TCGA-C8-A26V 47 female Asian Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 0.02 LumB East Asian TCGA.C8.A26V.01A.11R.A16F.07
TCGA-C8-A278 61 female Asian Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 0.02 Her2 East Asian TCGA.C8.A278.01A.11R.A169.07
TCGA-C8-A8HQ 53 female Asian Primary solid Tumor postmenopausal mucinous carcinoma positive positive negative NA NA alive 0.02 NA East Asian TCGA.C8.A8HQ.01A.11R.A36F.07
TCGA-AN-A03X 74 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.03 LumA European TCGA.AN.A03X.01A.21R.A00Z.07
TCGA-AN-A03Y 66 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.03 LumB European TCGA.AN.A03Y.01A.21R.A00Z.07
TCGA-AN-A046 68 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.03 LumA European TCGA.AN.A046.01A.21R.A034.07
TCGA-AN-A0AR 55 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 0.03 Basal European TCGA.AN.A0AR.01A.11R.A00Z.07
TCGA-AN-A0AS 70 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 0.03 LumA European TCGA.AN.A0AS.01A.11R.A00Z.07
TCGA-AN-A0AT 62 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 0.03 Basal European TCGA.AN.A0AT.01A.11R.A034.07
TCGA-AN-A0FV 58 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 0.03 Her2 European TCGA.AN.A0FV.01A.11R.A00Z.07
TCGA-AN-A0FX 52 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 0.03 Basal European TCGA.AN.A0FX.01A.11R.A034.07
TCGA-AN-A0FY 55 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.03 LumB European TCGA.AN.A0FY.01A.11R.A034.07
TCGA-AN-A0FZ 45 female White Primary solid Tumor premenopausal IDC positive negative positive NA NA alive 0.03 LumA European TCGA.AN.A0FZ.01A.11R.A034.07
TCGA-AN-A0XN 68 female White Primary solid Tumor postmenopausal IDC negative positive negative NA NA alive 0.03 LumA European TCGA.AN.A0XN.01A.21R.A109.07
TCGA-AN-A0XR 55 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 0.03 LumB European TCGA.AN.A0XR.01A.11R.A109.07
TCGA-AN-A0XS 63 female White Primary solid Tumor postmenopausal IDC negative positive negative NA NA alive 0.03 LumA European TCGA.AN.A0XS.01A.22R.A109.07
TCGA-AN-A0XT 54 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 0.03 LumA European TCGA.AN.A0XT.01A.11R.A109.07
TCGA-AN-A0XU 54 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 0.03 Basal European TCGA.AN.A0XU.01A.11R.A109.07
TCGA-AN-A0FW 67 female White Primary solid Tumor postmenopausal IDC positive Indeterminate negative NA NA alive 0.03 LumA European TCGA.AN.A0FW.01A.11R.A034.07
TCGA-E2-A1IL 78 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 0.04 LumA European TCGA.E2.A1IL.01A.11R.A14D.07
TCGA-AN-A0G0 56 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 0.04 NA European TCGA.AN.A0G0.01A.11R.A034.07
TCGA-AN-A049 62 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.05 LumA European TCGA.AN.A049.01A.21R.A00Z.07
TCGA-E9-A1R2 51 female White Primary solid Tumor postmenopausal IDC positive negative equivocal NA NA alive 0.05 LumA European TCGA.E9.A1R2.01A.11R.A14D.07
TCGA-E9-A1RD 67 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.05 LumA European TCGA.E9.A1RD.01A.11R.A157.07
TCGA-E9-A1RD 67 female White Solid Tissue Normal postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.05 LumA European TCGA.E9.A1RD.11A.33R.A157.07
TCGA-E9-A244 54 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.06 Basal European TCGA.E9.A244.01A.11R.A169.07
TCGA-E9-A227 42 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.07 LumA European TCGA.E9.A227.01A.11R.A157.07
TCGA-D8-A27R 41 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 0.08 LumB European TCGA.D8.A27R.01A.11R.A16F.07
TCGA-E9-A1R4 66 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.08 LumB European TCGA.E9.A1R4.01A.21R.A14D.07
TCGA-E9-A249 45 female White Primary solid Tumor premenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.08 LumB European TCGA.E9.A249.01A.11R.A169.07
TCGA-A8-A08A 89 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.08 LumA European TCGA.A8.A08A.01A.11R.A32Y.07
TCGA-A8-A09W 70 female not available Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 0.08 LumB European TCGA.A8.A09W.01A.11R.A00Z.07
TCGA-A8-A0A7 57 female not available Primary solid Tumor postmenopausal ILC negative negative positive NA NA alive 0.08 Her2 European TCGA.A8.A0A7.01A.11R.A00Z.07
TCGA-A8-A06Q 63 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.08 LumB European TCGA.A8.A06Q.01A.11R.A034.07
TCGA-A8-A06Z 84 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.08 LumB European TCGA.A8.A06Z.01A.11R.A00Z.07
TCGA-A8-A09C 69 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.08 LumB European TCGA.A8.A09C.01A.11R.A00Z.07
TCGA-A8-A09N 57 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.08 LumB European TCGA.A8.A09N.01A.11R.A00Z.07
TCGA-AC-A2QH 58 female White Primary solid Tumor postmenopausal metaplastic carcinoma negative negative negative NA NA alive 0.08 Basal European TCGA.AC.A2QH.01A.11R.A18M.07
TCGA-AC-A8OQ 72 female Black or African American Primary solid Tumor postmenopausal IDC negative negative Indeterminate NA NA alive 0.09 Basal African_admix TCGA.AC.A8OQ.01A.11R.A41B.07
TCGA-E2-A15K 58 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 0.09 LumB European TCGA.E2.A15K.01A.11R.A12P.07
TCGA-E2-A15K 58 female White Solid Tissue Normal postmenopausal IDC positive positive equivocal NA NA alive 0.09 LumB European TCGA.E2.A15K.11A.13R.A12P.07
TCGA-E9-A1RF 68 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.1 LumA European TCGA.E9.A1RF.01A.11R.A157.07
TCGA-E9-A1RF 68 female White Solid Tissue Normal postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.1 LumA European TCGA.E9.A1RF.11A.32R.A157.07
TCGA-AC-A8OR 75 female White Primary solid Tumor postmenopausal mucinous carcinoma positive positive negative NA NA alive 0.11 NA European TCGA.AC.A8OR.01A.21R.A41B.07
TCGA-E2-A15H 38 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 0.11 LumA European TCGA.E2.A15H.01A.11R.A12D.07
TCGA-E9-A1R5 63 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.11 LumA European TCGA.E9.A1R5.01A.11R.A14M.07
TCGA-E9-A243 52 female White Primary solid Tumor perimenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.12 Basal European TCGA.E9.A243.01A.21R.A169.07
TCGA-AC-A2FB 65 female White Primary solid Tumor not available ILC positive positive positive NA NA alive 0.12 LumA European TCGA.AC.A2FB.01A.11R.A17B.07
TCGA-AC-A2FB 65 female White Solid Tissue Normal not available ILC positive positive positive NA NA alive 0.12 LumA European TCGA.AC.A2FB.11A.13R.A17B.07
TCGA-E9-A1RI 43 female White Primary solid Tumor premenopausal IDC/ILC not evaluated not evaluated not evaluated NA NA alive 0.13 NA European TCGA.E9.A1RI.01A.11R.A169.07
TCGA-E9-A1RI 43 female White Solid Tissue Normal premenopausal IDC/ILC not evaluated not evaluated not evaluated NA NA alive 0.13 NA European TCGA.E9.A1RI.11A.41R.A169.07
TCGA-D8-A145 80 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 0.13 LumA European TCGA.D8.A145.01A.11R.A115.07
TCGA-D8-A27P 64 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.13 LumA European TCGA.D8.A27P.01A.11R.A16F.07
TCGA-D8-A1XS 48 male White Primary solid Tumor not applicable ductal/micropapillary positive positive positive NA NA alive 0.14 NA European TCGA.D8.A1XS.01A.11R.A14M.07
TCGA-AC-A6NO 43 female Black or African American Primary solid Tumor unknown IDC positive positive negative NA NA alive 0.14 LumA African_admix TCGA.AC.A6NO.01A.12R.A33J.07
TCGA-AN-A04D 58 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 0.14 Basal European TCGA.AN.A04D.01A.21R.A034.07
TCGA-A7-A3RF 79 female White Primary solid Tumor postmenopausal mucinous carcinoma positive positive negative metastasis bone>liver alive 0.15 NA European TCGA.A7.A3RF.01A.11R.A22K.07
TCGA-AN-A04C 51 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 0.15 Her2 European TCGA.AN.A04C.01A.21R.A034.07
TCGA-AC-A3W5 65 female Black or African American Primary solid Tumor not evaluated ILC positive positive not evaluated NA NA alive 0.15 Her2 African TCGA.AC.A3W5.01A.11R.A22K.07
TCGA-AC-A62Y 79 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 0.15 LumA European TCGA.AC.A62Y.01A.11R.A29R.07
TCGA-C8-A132 56 female Asian Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA alive 0.16 LumA East Asian TCGA.C8.A132.01A.31R.A115.07
TCGA-OL-A66P 75 female Black or African American Primary solid Tumor not available IDC negative negative not evaluated NA NA alive 0.16 Her2 African TCGA.OL.A66P.01A.11R.A31O.07
TCGA-E9-A248 51 female White Primary solid Tumor perimenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.16 Her2 European TCGA.E9.A248.01A.11R.A169.07
TCGA-BH-A18G 81 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 0.17 Basal European TCGA.BH.A18G.01A.11R.A12D.07
TCGA-D8-A142 74 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 0.17 Basal European TCGA.D8.A142.01A.11R.A115.07
TCGA-AC-A5EH 76 female Black or African American Primary solid Tumor not available IDC positive negative negative NA NA alive 0.17 Her2 African_admix TCGA.AC.A5EH.01A.11R.A28M.07
TCGA-E9-A1R3 70 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.18 LumA European TCGA.E9.A1R3.01A.31R.A14M.07
TCGA-OK-A5Q2 59 female not available Primary solid Tumor unknown ILC positive positive negative NA NA alive 0.18 LumA African TCGA.OK.A5Q2.01A.11R.A27Q.07
TCGA-A7-A26J 49 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.19 LumA European TCGA.A7.A26J.01A.11R.A169.07
TCGA-C8-A131 82 female Asian Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 0.19 Basal East Asian TCGA.C8.A131.01A.11R.A115.07
TCGA-AC-A8OS 71 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 0.19 LumA European TCGA.AC.A8OS.01A.12R.A41B.07
TCGA-C8-A1HM 74 female Asian Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.19 LumB East Asian TCGA.C8.A1HM.01A.12R.A137.07
TCGA-AC-A23E 50 female White Primary solid Tumor not available IDC positive positive not evaluated NA NA alive 0.2 LumA European TCGA.AC.A23E.01A.11R.A157.07
TCGA-BH-A0HL 56 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 0.2 NA European TCGA.BH.A0HL.01A.11R.A10U.07
TCGA-D8-A1Y2 71 female White Primary solid Tumor postmenopausal IDC positive positive Indeterminate NA NA alive 0.2 LumB European TCGA.D8.A1Y2.01A.11R.A157.07
TCGA-D8-A27V 62 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 0.2 LumA European TCGA.D8.A27V.01A.12R.A17B.07
TCGA-AC-A7VB 51 female Black or African American Primary solid Tumor unknown IDC positive negative not evaluated NA NA alive 0.2 LumB African_admix TCGA.AC.A7VB.01A.11R.A352.07
TCGA-A7-A3J1 63 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 0.21 NA European TCGA.A7.A3J1.01A.11R.A213.07
TCGA-D8-A1XG 86 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 0.21 LumA European TCGA.D8.A1XG.01A.11R.A14D.07
TCGA-A7-A3J0 62 female White Primary solid Tumor postmenopausal mucinous carcinoma positive positive negative NA NA alive 0.21 NA European TCGA.A7.A3J0.01A.11R.A213.07
TCGA-BH-A0HO 48 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.21 LumA European TCGA.BH.A0HO.01A.11R.A034.07
TCGA-AQ-A54N 51 female Black or African American Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 0.21 NA African TCGA.AQ.A54N.01A.11R.A266.07
TCGA-BH-A0DS 71 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.21 LumA European TCGA.BH.A0DS.01A.11R.A056.07
TCGA-HN-A2NL 56 female not available Primary solid Tumor postmenopausal ILC negative negative negative NA NA alive 0.22 Basal European TCGA.HN.A2NL.01A.11R.A18M.07
TCGA-LL-A6FQ 77 female Black or African American Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.22 LumA African TCGA.LL.A6FQ.01A.11R.A31O.07
TCGA-D8-A1XY 74 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.22 LumA European TCGA.D8.A1XY.01A.11R.A14M.07
TCGA-AR-A24P 47 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 0.23 LumA European TCGA.AR.A24P.01A.11R.A169.07
TCGA-E9-A1R6 63 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.23 LumA European TCGA.E9.A1R6.01A.11R.A14D.07
TCGA-D8-A1X7 40 female White Primary solid Tumor premenopausal ductal partially papillary positive positive negative NA NA alive 0.23 NA European TCGA.D8.A1X7.01A.11R.A14M.07
TCGA-MS-A51U 44 female White Primary solid Tumor not available ILC positive positive negative NA NA alive 0.23 NA European TCGA.MS.A51U.01A.31R.A266.07
TCGA-AN-A04A 36 female White Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 0.25 LumA European TCGA.AN.A04A.01A.21R.A034.07
TCGA-E9-A6HE 45 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 0.25 LumA European TCGA.E9.A6HE.01A.11R.A31O.07
TCGA-AC-A3TM 50 female White Primary solid Tumor perimenopausal ILC positive positive equivocal NA NA alive 0.25 NA European TCGA.AC.A3TM.01A.11R.A22K.07
TCGA-C8-A130 52 female Asian Primary solid Tumor perimenopausal IDC positive positive equivocal NA NA alive 0.26 LumB East Asian TCGA.C8.A130.01A.31R.A115.07
TCGA-D8-A1JF 79 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 0.26 Her2 European TCGA.D8.A1JF.01A.11R.A13Q.07
TCGA-D8-A1XF 45 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.27 LumB European TCGA.D8.A1XF.01A.11R.A14D.07
TCGA-LL-A5YO 50 female Black or African American Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 0.27 Her2 African TCGA.LL.A5YO.01A.21R.A28M.07
TCGA-BH-A0DQ 42 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.27 LumA European TCGA.BH.A0DQ.01A.11R.A084.07
TCGA-BH-A0DQ 42 female White Solid Tissue Normal premenopausal IDC positive positive negative NA NA alive 0.27 LumA European TCGA.BH.A0DQ.11A.12R.A089.07
TCGA-BH-A5IZ 51 female Black or African American Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 0.27 Basal African TCGA.BH.A5IZ.01A.11R.A27Q.07
TCGA-LL-A7T0 70 female Black or African American Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.27 LumB African TCGA.LL.A7T0.01A.31R.A352.07
TCGA-C8-A1HN 56 female Asian Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 0.27 LumB East Asian TCGA.C8.A1HN.01A.11R.A137.07
TCGA-LL-A5YP 49 female Black or African American Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 0.27 Basal African TCGA.LL.A5YP.01A.21R.A28M.07
TCGA-BH-A0E0 38 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 0.37 Basal European TCGA.BH.A0E0.01A.11R.A056.07
TCGA-BH-A0E0 38 female White Solid Tissue Normal premenopausal IDC negative negative negative NA NA alive 0.37 Basal European TCGA.BH.A0E0.11A.13R.A089.07
TCGA-BH-A6R9 61 female White Primary solid Tumor postmenopausal metaplastic carcinoma negative positive negative NA NA alive 0.44 Normal European TCGA.BH.A6R9.01A.21R.A32P.07
TCGA-AN-A0XV 67 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.44 LumA European TCGA.AN.A0XV.01A.11R.A109.07
TCGA-AN-A0XL 61 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.45 LumA European TCGA.AN.A0XL.01A.11R.A10J.07
TCGA-E2-A2P6 77 female not available Primary solid Tumor postmenopausal ILC positive positive not evaluated NA NA alive 0.46 LumA American TCGA.E2.A2P6.01A.11R.A19W.07
TCGA-AN-A0XW 36 female White Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 0.47 LumA European TCGA.AN.A0XW.01A.11R.A109.07
TCGA-BH-A0RX 59 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 0.47 Basal European TCGA.BH.A0RX.01A.21R.A084.07
TCGA-AN-A0FF 32 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.47 LumB European TCGA.AN.A0FF.01A.11R.A034.07
TCGA-BH-A0HK 81 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 0.49 LumA European TCGA.BH.A0HK.01A.11R.A056.07
TCGA-BH-A0HK 81 female White Solid Tissue Normal postmenopausal IDC positive negative negative NA NA alive 0.49 LumA European TCGA.BH.A0HK.11A.11R.A089.07
TCGA-EW-A1PC 66 female Black or African American Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.51 NA African TCGA.EW.A1PC.01B.11R.A21T.07
TCGA-AN-A0FD 71 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.54 LumA European TCGA.AN.A0FD.01A.11R.A034.07
TCGA-BH-A28Q 46 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 0.54 LumA European TCGA.BH.A28Q.01A.11R.A16F.07
TCGA-AN-A0FS 55 female White Primary solid Tumor perimenopausal ILC positive negative positive NA NA alive 0.57 LumA European TCGA.AN.A0FS.01A.11R.A034.07
TCGA-AN-A0FK 88 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.58 LumA European TCGA.AN.A0FK.01A.11R.A034.07
TCGA-AN-A0FT 63 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.59 LumA European TCGA.AN.A0FT.01A.11R.A034.07
TCGA-B6-A400 43 female Black or African American Primary solid Tumor unknown IDC negative negative negative NA NA alive 0.59 NA African TCGA.B6.A400.01A.11R.A239.07
TCGA-LD-A7W5 52 female Black or African American Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.59 LumA African TCGA.LD.A7W5.01A.22R.A352.07
TCGA-AN-A0FN 61 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 0.6 LumA European TCGA.AN.A0FN.01A.11R.A034.07
TCGA-BH-A18I 53 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.6 LumA European TCGA.BH.A18I.01A.11R.A12D.07
TCGA-A2-A4RW 49 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 0.61 NA European TCGA.A2.A4RW.01A.21R.A266.07
TCGA-AN-A0AK 76 female White Primary solid Tumor postmenopausal IDC positive negative positive NA NA alive 0.61 LumB European TCGA.AN.A0AK.01A.21R.A00Z.07
TCGA-AR-A2LL 70 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 0.61 NA European TCGA.AR.A2LL.01A.11R.A180.07
TCGA-GI-A2C8 63 female White Primary solid Tumor not available IDC positive positive negative NA NA alive 0.62 LumA European TCGA.GI.A2C8.01A.11R.A16F.07
TCGA-GI-A2C8 63 female White Solid Tissue Normal not available IDC positive positive negative NA NA alive 0.62 LumA European TCGA.GI.A2C8.11A.22R.A16F.07
TCGA-AN-A0AL 41 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 0.62 Basal European TCGA.AN.A0AL.01A.11R.A00Z.07
TCGA-A7-A0CG 78 female White Primary solid Tumor postmenopausal ILC/IDC (grade 1) positive negative negative NA NA alive 0.63 NA European TCGA.A7.A0CG.01A.12R.A056.07
TCGA-AN-A0FL 62 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 0.63 Basal European TCGA.AN.A0FL.01A.11R.A034.07
TCGA-A7-A0CH 79 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.64 LumA European TCGA.A7.A0CH.01A.21R.A00Z.07
TCGA-A7-A0CH 79 female White Solid Tissue Normal postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.64 LumA European TCGA.A7.A0CH.11A.32R.A089.07
TCGA-A1-A0SM 77 male White Primary solid Tumor not applicable IDC positive negative positive NA NA alive 0.66 NA European TCGA.A1.A0SM.01A.11R.A084.07
TCGA-AN-A0FJ 59 female White Primary solid Tumor perimenopausal IDC positive negative positive NA NA alive 0.66 Basal European TCGA.AN.A0FJ.01A.11R.A00Z.07
TCGA-E2-A56Z 69 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 0.69 LumB African_admix TCGA.E2.A56Z.01A.12R.A29R.07
TCGA-EW-A1IY 38 female Asian Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.71 LumB East Asian TCGA.EW.A1IY.01A.11R.A13Q.07
TCGA-A1-A0SB 70 female White Primary solid Tumor postmenopausal adenoid cystic carcinoma positive negative negative NA NA alive 0.71 NA European TCGA.A1.A0SB.01A.11R.A144.07
TCGA-A7-A6VY 48 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 0.73 Basal African_admix TCGA.A7.A6VY.01A.12R.A33J.07
TCGA-A7-A0DB 56 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.73 LumA European TCGA.A7.A0DB.01A.11R.A00Z.07
TCGA-A7-A0DB 56 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA alive 0.73 LumA European TCGA.A7.A0DB.11A.33R.A089.07
TCGA-BH-A18F 50 female White Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 0.73 LumA European TCGA.BH.A18F.01A.11R.A12D.07
TCGA-OL-A97C 67 female Black or African American Primary solid Tumor postmenopausal malignant phyllodes negative negative not evaluated metastasis lung alive 0.74 NA African TCGA.OL.A97C.01A.32R.A41B.07
TCGA-A7-A0D9 37 female White Primary solid Tumor premenopausal IDC positive negative negative NA NA alive 0.75 LumA European TCGA.A7.A0D9.01A.31R.A056.07
TCGA-A7-A0D9 37 female White Solid Tissue Normal premenopausal IDC positive negative negative NA NA alive 0.75 LumA European TCGA.A7.A0D9.11A.53R.A089.07
TCGA-A8-A07R 80 female not available Primary solid Tumor not available IDC negative negative positive NA NA alive 0.75 NA European TCGA.A8.A07R.01A.21R.A034.07
TCGA-A8-A09R 82 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.75 LumB European TCGA.A8.A09R.01A.11R.A00Z.07
TCGA-A8-A079 69 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.75 LumB European TCGA.A8.A079.01A.21R.A00Z.07
TCGA-A7-A6VW 48 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 0.78 Basal African_admix TCGA.A7.A6VW.01A.21R.A33J.07
TCGA-BH-AB28 53 female White Primary solid Tumor unknown ILC positive positive negative NA NA alive 0.79 LumA European TCGA.BH.AB28.01A.31R.A41B.07
TCGA-D8-A27K 47 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.79 LumA European TCGA.D8.A27K.01A.11R.A16F.07
TCGA-E9-A2JT 63 female White Primary solid Tumor postmenopausal ILC not evaluated not evaluated not evaluated NA NA alive 0.79 LumA European TCGA.E9.A2JT.01A.22R.A18M.07
TCGA-E2-A15O 89 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal locoregional recurrence not available alive 0.79 LumA African TCGA.E2.A15O.01A.11R.A115.07
TCGA-BH-A0E6 69 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 0.8 Basal European TCGA.BH.A0E6.01A.11R.A034.07
TCGA-BH-A6R8 46 female Black or African American Primary solid Tumor unknown IDC positive positive not evaluated NA NA alive 0.8 LumA African TCGA.BH.A6R8.01A.21R.A33J.07
TCGA-AO-A0J4 41 female Black or African American Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 0.8 Basal African TCGA.AO.A0J4.01A.11R.A034.07
TCGA-PL-A8LZ 29 female Black or African American Primary solid Tumor premenopausal IDC not evaluated not evaluated not evaluated NA NA alive 0.83 Basal African TCGA.PL.A8LZ.01A.31R.A36F.07
TCGA-5T-A9QA 52 female Black or African American Primary solid Tumor unknown IDC/mucinous positive negative equivocal NA NA alive 0.83 NA African TCGA.5T.A9QA.01A.11R.A41B.07
TCGA-AN-A0AJ 79 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.83 LumB European TCGA.AN.A0AJ.01A.11R.A00Z.07
TCGA-A8-A07O 51 female not available Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 0.83 Basal European TCGA.A8.A07O.01A.11R.A00Z.07
TCGA-A8-A07W 76 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.83 LumB European TCGA.A8.A07W.01A.11R.A00Z.07
TCGA-A8-A099 76 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.83 LumA European TCGA.A8.A099.01A.11R.A00Z.07
TCGA-A8-A09A 40 female not available Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.83 LumA European TCGA.A8.A09A.01A.11R.A00Z.07
TCGA-A7-A0CE 57 female White Primary solid Tumor indeterminate IDC negative negative equivocal NA NA alive 0.85 Basal European TCGA.A7.A0CE.01A.11R.A00Z.07
TCGA-A7-A0CE 57 female White Solid Tissue Normal indeterminate IDC negative negative equivocal NA NA alive 0.85 Basal European TCGA.A7.A0CE.11A.21R.A089.07
TCGA-A7-A6VV 51 female Black or African American Primary solid Tumor perimenopausal IDC negative negative negative NA NA alive 0.86 Basal African TCGA.A7.A6VV.01A.22R.A33J.07
TCGA-A7-A6VX 68 female Black or African American Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.87 LumB African TCGA.A7.A6VX.01A.12R.A33J.07
TCGA-C8-A1HL 38 female Asian Primary solid Tumor premenopausal Infiltrating mucinous-papillary ductal carcinoma positive negative equivocal NA NA alive 0.87 NA East Asian TCGA.C8.A1HL.01A.11R.A137.07
TCGA-A2-A25F 66 female White Primary solid Tumor postmenopausal IDC negative positive negative NA NA alive 0.88 Basal European TCGA.A2.A25F.01A.11R.A169.07
TCGA-A7-A3IZ 62 female White Primary solid Tumor postmenopausal ILC positive negative equivocal NA NA alive 0.88 NA European TCGA.A7.A3IZ.01A.11R.A213.07
TCGA-LD-A9QF 73 female Black or African American Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 0.88 Normal African_admix TCGA.LD.A9QF.01A.32R.A41B.07
TCGA-BH-A28O 50 female White Primary solid Tumor not available ILC positive positive negative NA NA alive 0.89 NA European TCGA.BH.A28O.01A.11R.A22K.07
TCGA-A7-A5ZW 47 female Black or African American Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 0.89 LumA African_admix TCGA.A7.A5ZW.01A.12R.A29R.07
TCGA-BH-A0GZ 62 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 0.9 LumA European TCGA.BH.A0GZ.01A.11R.A056.07
TCGA-AC-A23G 76 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 0.9 NA European TCGA.AC.A23G.01A.11R.A213.07
TCGA-C8-A1HF 48 female Asian Primary solid Tumor premenopausal IDC negative positive positive NA NA alive 0.91 Her2 East Asian TCGA.C8.A1HF.01A.11R.A137.07
TCGA-A8-A07P 68 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 0.91 LumA European TCGA.A8.A07P.01A.11R.A00Z.07
TCGA-A7-A5ZX 48 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 0.92 LumA European TCGA.A7.A5ZX.01A.12R.A29R.07
TCGA-E2-A1IU 60 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.92 LumA European TCGA.E2.A1IU.01A.11R.A14D.07
TCGA-C8-A1HI 40 female Asian Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.94 LumA East Asian TCGA.C8.A1HI.01A.11R.A137.07
TCGA-A7-A3IY 71 female White Primary solid Tumor postmenopausal mucinous carcinoma positive positive negative NA NA alive 0.94 NA European TCGA.A7.A3IY.01A.21R.A21T.07
TCGA-C8-A1HG 50 female Asian Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 0.94 LumB East Asian TCGA.C8.A1HG.01A.11R.A137.07
TCGA-W8-A86G 66 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 0.95 LumA European TCGA.W8.A86G.01A.21R.A36F.07
TCGA-4H-AAAK 50 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 0.95 LumA European TCGA.4H.AAAK.01A.12R.A41B.07
TCGA-AO-A1KS 69 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 0.96 LumB European TCGA.AO.A1KS.01A.11R.A13Q.07
TCGA-JL-A3YX 46 female Asian Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 0.96 LumA South Asian_admix TCGA.JL.A3YX.01A.11R.A22U.07
TCGA-BH-A0BW 71 female Black or African American Primary solid Tumor postmenopausal IDC negative negative not available NA NA alive 0.97 Basal African_admix TCGA.BH.A0BW.01A.11R.A115.07
TCGA-BH-A0BW 71 female Black or African American Solid Tissue Normal postmenopausal IDC negative negative not available NA NA alive 0.97 Basal African_admix TCGA.BH.A0BW.11A.12R.A115.07
TCGA-C8-A12M 70 female Asian Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 0.98 LumB East Asian TCGA.C8.A12M.01A.11R.A115.07
TCGA-C8-A12N 58 female Asian Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.98 LumA East Asian TCGA.C8.A12N.01A.11R.A115.07
TCGA-C8-A12P 55 female Asian Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 0.98 Her2 East Asian TCGA.C8.A12P.01A.11R.A115.07
TCGA-JL-A3YW 49 female Asian Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 0.99 NA South Asian TCGA.JL.A3YW.01A.12R.A239.07
TCGA-D8-A13Y 52 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 0.99 LumB European TCGA.D8.A13Y.01A.11R.A115.07
TCGA-C8-A12L 67 female Asian Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 0.99 Her2 East Asian TCGA.C8.A12L.01A.11R.A115.07
TCGA-A7-A426 50 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 1.0 NA European TCGA.A7.A426.01A.22R.A24H.07
TCGA-A8-A07J 35 female not available Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.0 LumA European TCGA.A8.A07J.01A.11R.A00Z.07
TCGA-A8-A08I 53 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.0 LumB European TCGA.A8.A08I.01A.11R.A00Z.07
TCGA-A8-A097 65 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 1.0 LumA European TCGA.A8.A097.01A.11R.A034.07
TCGA-A8-A09B 58 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.0 LumA European TCGA.A8.A09B.01A.11R.A00Z.07
TCGA-A8-A0A1 84 female not available Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.0 LumA European TCGA.A8.A0A1.01A.11R.A00Z.07
TCGA-E9-A1N8 48 female White Primary solid Tumor postmenopausal IDC negative not evaluated negative NA NA alive 1.0 Basal European TCGA.E9.A1N8.01A.11R.A144.07
TCGA-D8-A1JG 62 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 1.0 Her2 European TCGA.D8.A1JG.01B.11R.A13Q.07
TCGA-A7-A5ZV 62 female Black or African American Primary solid Tumor postmenopausal infiltrating carcinoma NOS negative negative equivocal NA NA alive 1.01 NA African TCGA.A7.A5ZV.01A.11R.A28M.07
TCGA-D8-A1JS 77 female White Primary solid Tumor postmenopausal papillary positive positive negative NA NA alive 1.02 NA European TCGA.D8.A1JS.01A.11R.A13Q.07
TCGA-EW-A1IW 80 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 1.02 LumA European TCGA.EW.A1IW.01A.11R.A13Q.07
TCGA-A7-A0CD 66 female White Primary solid Tumor indeterminate IDC positive positive equivocal NA NA alive 1.02 LumA European TCGA.A7.A0CD.01A.11R.A00Z.07
TCGA-A7-A0DA 62 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.02 Basal European TCGA.A7.A0DA.01A.31R.A115.07
TCGA-AC-A6IX 49 female White Primary solid Tumor perimenopausal ILC positive positive not evaluated NA NA alive 1.02 LumA European TCGA.AC.A6IX.01A.12R.A32P.07
TCGA-D8-A27W 55 female White Primary solid Tumor postmenopausal mucinous carcinoma positive positive equivocal NA NA alive 1.02 NA European TCGA.D8.A27W.01A.11R.A16F.07
TCGA-AN-A0XO 59 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 1.03 LumA European TCGA.AN.A0XO.01A.11R.A109.07
TCGA-C8-A1HE 59 female Asian Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.03 LumA East Asian TCGA.C8.A1HE.01A.11R.A13Q.07
TCGA-C8-A1HO 34 female Asian Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.03 LumA East Asian TCGA.C8.A1HO.01A.11R.A13Q.07
TCGA-E9-A295 71 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 1.03 LumA European TCGA.E9.A295.01A.11R.A16F.07
TCGA-C8-A26X 58 female Asian Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.03 Her2 East Asian TCGA.C8.A26X.01A.31R.A16F.07
TCGA-C8-A137 34 female Asian Primary solid Tumor premenopausal IDC negative negative positive locoregional recurrence not available alive 1.04 Her2 East Asian TCGA.C8.A137.01A.11R.A115.07
TCGA-E9-A228 58 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 1.04 LumB European TCGA.E9.A228.01A.31R.A157.07
TCGA-C8-A12Z 45 female Asian Primary solid Tumor perimenopausal IDC negative negative positive NA NA alive 1.05 Her2 East Asian TCGA.C8.A12Z.01A.11R.A115.07
TCGA-C8-A134 52 female Asian Primary solid Tumor perimenopausal IDC negative negative equivocal NA NA alive 1.05 Basal East Asian TCGA.C8.A134.01A.11R.A115.07
TCGA-C8-A12O 50 female Asian Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.05 LumA East Asian TCGA.C8.A12O.01A.11R.A115.07
TCGA-C8-A12U 46 female Asian Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.05 LumB East Asian TCGA.C8.A12U.01A.11R.A115.07
TCGA-C8-A12V 55 female Asian Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.05 Basal East Asian TCGA.C8.A12V.01A.11R.A115.07
TCGA-C8-A12X 62 female Asian Primary solid Tumor postmenopausal mucinous carcinoma positive positive negative NA NA alive 1.05 NA East Asian TCGA.C8.A12X.01A.11R.A115.07
TCGA-D8-A1XW 53 female White Primary solid Tumor postmenopausal IDC negative positive negative NA NA alive 1.05 Normal European TCGA.D8.A1XW.01A.11R.A14M.07
TCGA-BH-A0HU 52 female White Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 1.07 LumB European TCGA.BH.A0HU.01A.11R.A034.07
TCGA-C8-A135 64 female Asian Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 1.08 Her2 East Asian TCGA.C8.A135.01A.11R.A115.07
TCGA-LL-A5YM 88 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal locoregional recurrence skin chest wall alive 1.08 LumB African TCGA.LL.A5YM.01A.11R.A28M.07
TCGA-D8-A1XU 56 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.08 LumA European TCGA.D8.A1XU.01A.11R.A14M.07
TCGA-A8-A06O 60 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.08 LumB European TCGA.A8.A06O.01A.11R.A00Z.07
TCGA-A8-A06P 63 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.08 LumA European TCGA.A8.A06P.01A.11R.A00Z.07
TCGA-A8-A086 59 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.08 LumA European TCGA.A8.A086.01A.11R.A00Z.07
TCGA-A8-A09D 47 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.08 LumA European TCGA.A8.A09D.01A.11R.A00Z.07
TCGA-A8-A0A4 73 female not available Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.08 LumA European TCGA.A8.A0A4.01A.11R.A00Z.07
TCGA-D8-A27H 72 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.09 Basal European TCGA.D8.A27H.01A.11R.A16F.07
TCGA-D8-A27T 53 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.09 LumA European TCGA.D8.A27T.01A.11R.A16F.07
TCGA-E9-A1N9 58 female White Primary solid Tumor postmenopausal IDC/ILC negative positive positive NA NA alive 1.09 NA European TCGA.E9.A1N9.01A.11R.A14D.07
TCGA-E9-A1N9 58 female White Solid Tissue Normal postmenopausal IDC/ILC negative positive positive NA NA alive 1.09 NA European TCGA.E9.A1N9.11A.71R.A14D.07
TCGA-E9-A22D 38 female White Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 1.1 LumB European TCGA.E9.A22D.01A.11R.A157.07
TCGA-LD-A74U 79 female White Primary solid Tumor not available \ILC, classical type, focal pleomorphic type\"" positive negative negative NA NA alive 1.1 NA European TCGA.LD.A74U.01A.13R.A33J.07
TCGA-D8-A140 62 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 1.1 LumA European TCGA.D8.A140.01A.11R.A115.07
TCGA-EW-A1J2 50 female Black or African American Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 1.1 LumA South Asian TCGA.EW.A1J2.01A.21R.A13Q.07
TCGA-LD-A7W6 54 female White Primary solid Tumor postmenopausal \ILC, mixed classical (70%) and pleomorphic/solid (30%) types\"" positive positive negative NA NA alive 1.11 NA European TCGA.LD.A7W6.01A.81R.A352.07
TCGA-D8-A1JT 70 female White Primary solid Tumor postmenopausal ductal and papillary positive positive equivocal NA NA alive 1.11 NA European TCGA.D8.A1JT.01A.31R.A13Q.07
TCGA-E9-A229 37 female White Primary solid Tumor premenopausal IDC not evaluated not evaluated not evaluated NA NA alive 1.11 LumA European TCGA.E9.A229.01A.31R.A157.07
TCGA-C8-A8HR 49 female Asian Primary solid Tumor perimenopausal ILC not evaluated not evaluated not evaluated NA NA alive 1.12 Normal East Asian TCGA.C8.A8HR.01A.11R.A36F.07
TCGA-D8-A27G 75 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 1.12 LumA European TCGA.D8.A27G.01A.11R.A16F.07
TCGA-D8-A27M 59 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.12 Basal European TCGA.D8.A27M.01A.11R.A16F.07
TCGA-GM-A5PV 63 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated NA NA alive 1.13 LumA European TCGA.GM.A5PV.01A.11R.A28M.07
TCGA-AC-A6IW 73 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.13 Basal African TCGA.AC.A6IW.01A.12R.A33J.07
TCGA-BH-A0HP 65 female White Primary solid Tumor postmenopausal ILC positive negative negative NA NA alive 1.13 LumA European TCGA.BH.A0HP.01A.12R.A084.07
TCGA-A1-A0SJ 39 female Black or African American Primary solid Tumor not available IDC positive positive equivocal NA NA alive 1.14 LumA African_admix TCGA.A1.A0SJ.01A.11R.A084.07
TCGA-AC-A62X 72 female Black or African American Primary solid Tumor postmenopausal IDC positive negative not evaluated NA NA alive 1.14 Basal African TCGA.AC.A62X.01A.11R.A29R.07
TCGA-A7-A4SB 56 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.14 NA European TCGA.A7.A4SB.01A.21R.A266.07
TCGA-E9-A1NE 28 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.15 LumA European TCGA.E9.A1NE.01A.21R.A14M.07
TCGA-S3-AA11 67 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.15 LumA African TCGA.S3.AA11.01A.31R.A41B.07
TCGA-BH-A0DK 49 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.16 LumA European TCGA.BH.A0DK.01A.21R.A056.07
TCGA-BH-A0DK 49 female White Solid Tissue Normal premenopausal IDC positive positive negative NA NA alive 1.16 LumA European TCGA.BH.A0DK.11A.13R.A089.07
TCGA-EW-A1PD 61 male White Primary solid Tumor not applicable IDC positive positive equivocal NA NA alive 1.16 NA European TCGA.EW.A1PD.01A.11R.A144.07
TCGA-S3-AA17 64 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.16 LumB African_admix TCGA.S3.AA17.01A.11R.A41B.07
TCGA-A8-A07I 69 female not available Primary solid Tumor postmenopausal IDC positive negative positive NA NA alive 1.17 Her2 European TCGA.A8.A07I.01A.11R.A00Z.07
TCGA-D8-A1JH 56 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.17 LumA European TCGA.D8.A1JH.01A.11R.A13Q.07
TCGA-E2-A15S 34 female White Primary solid Tumor postmenopausal IDC positive negative equivocal NA NA alive 1.17 LumB European TCGA.E2.A15S.01A.11R.A115.07
TCGA-D8-A1Y3 61 female White Primary solid Tumor postmenopausal IDC positive positive Indeterminate NA NA alive 1.18 LumB European TCGA.D8.A1Y3.01A.11R.A157.07
TCGA-D8-A143 51 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.18 Basal European TCGA.D8.A143.01A.11R.A115.07
TCGA-D8-A1J8 77 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.18 LumB European TCGA.D8.A1J8.01A.11R.A13Q.07
TCGA-A1-A0SG 61 female White Primary solid Tumor postmenopausal micropapillary carcinoma invasive positive positive negative NA NA alive 1.19 NA European TCGA.A1.A0SG.01A.11R.A144.07
TCGA-BH-A0E2 49 female Black or African American Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.19 LumA African TCGA.BH.A0E2.01A.11R.A056.07
TCGA-A1-A0SD 59 female White Primary solid Tumor not available IDC positive positive negative NA NA alive 1.2 LumA European TCGA.A1.A0SD.01A.11R.A115.07
TCGA-C8-A27B 48 female Asian Primary solid Tumor perimenopausal IDC negative negative negative NA NA alive 1.2 Basal East Asian TCGA.C8.A27B.01A.11R.A169.07
TCGA-D8-A27I 58 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.2 LumA European TCGA.D8.A27I.01A.11R.A16F.07
TCGA-A2-A0YI 62 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.21 LumA European TCGA.A2.A0YI.01A.31R.A10J.07
TCGA-A7-A4SD 52 female Black or African American Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 1.21 Basal African TCGA.A7.A4SD.01A.11R.A266.07
TCGA-D8-A1XK 55 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.21 Basal European TCGA.D8.A1XK.01A.21R.A14M.07
TCGA-D8-A3Z5 54 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.21 NA European TCGA.D8.A3Z5.01A.41R.A24H.07
TCGA-LL-A740 61 female Black or African American Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 1.21 LumA African TCGA.LL.A740.01A.21R.A32P.07
TCGA-A2-A0YL 48 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 1.22 LumA European TCGA.A2.A0YL.01A.21R.A109.07
TCGA-A7-A4SC 62 female White Primary solid Tumor postmenopausal ILC positive negative equivocal NA NA alive 1.22 NA European TCGA.A7.A4SC.01A.12R.A266.07
TCGA-A7-A425 70 female White Primary solid Tumor postmenopausal ILC positive positive Indeterminate locoregional recurrence breast>bone alive 1.22 LumA European TCGA.A7.A425.01A.11R.A24H.07
TCGA-D8-A1JU 51 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.22 LumA European TCGA.D8.A1JU.01A.11R.A13Q.07
TCGA-LL-A5YN 46 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.22 LumA African TCGA.LL.A5YN.01A.11R.A28M.07
TCGA-A7-A56D 84 female Black or African American Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.23 LumA African TCGA.A7.A56D.01A.11R.A27Q.07
TCGA-E2-A158 43 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 1.23 Basal European TCGA.E2.A158.01A.11R.A12D.07
TCGA-E2-A158 43 female White Solid Tissue Normal premenopausal IDC negative negative negative NA NA alive 1.23 Basal European TCGA.E2.A158.11A.22R.A12D.07
TCGA-AC-A3OD 68 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.23 LumA European TCGA.AC.A3OD.01A.11R.A21T.07
TCGA-A7-A4SA 40 female White Primary solid Tumor premenopausal ILC positive negative negative NA NA alive 1.24 NA European TCGA.A7.A4SA.01A.11R.A266.07
TCGA-AC-A3TN 75 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 1.25 NA European TCGA.AC.A3TN.01A.11R.A22K.07
TCGA-E2-A15T 65 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.25 LumB European TCGA.E2.A15T.01A.11R.A115.07
TCGA-A8-A09M 75 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.25 LumB European TCGA.A8.A09M.01A.11R.A00Z.07
TCGA-A8-A09V 51 female not available Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 1.25 LumA European TCGA.A8.A09V.01A.11R.A034.07
TCGA-A8-A084 81 female not available Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 1.25 NA European TCGA.A8.A084.01A.21R.A00Z.07
TCGA-BH-A0H0 69 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.26 LumB European TCGA.BH.A0H0.01A.11R.A056.07
TCGA-D8-A1XV 84 female White Primary solid Tumor postmenopausal mucinous carcinoma positive positive equivocal NA NA alive 1.26 NA European TCGA.D8.A1XV.01A.11R.A14M.07
TCGA-EW-A6S9 34 female Black or African American Primary solid Tumor not available IDC positive positive positive NA NA alive 1.27 LumA African_admix TCGA.EW.A6S9.01A.22R.A33J.07
TCGA-D8-A1XZ 81 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 1.28 LumB European TCGA.D8.A1XZ.01A.11R.A14M.07
TCGA-XX-A899 46 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.28 LumA European TCGA.XX.A899.01A.11R.A36F.07
TCGA-A2-A0YF 67 female Black or African American Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 1.28 LumA African_admix TCGA.A2.A0YF.01A.21R.A109.07
TCGA-C8-A26Z 59 female Asian Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.29 LumA East Asian TCGA.C8.A26Z.01A.11R.A16F.07
TCGA-E2-A1LS 46 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 1.29 NA European TCGA.E2.A1LS.01A.12R.A157.07
TCGA-E2-A1LS 46 female White Solid Tissue Normal premenopausal IDC negative negative negative NA NA alive 1.29 NA European TCGA.E2.A1LS.11A.32R.A157.07
TCGA-AC-A3W7 66 female White Primary solid Tumor postmenopausal ILC positive negative negative NA NA alive 1.29 NA European TCGA.AC.A3W7.01A.11R.A22K.07
TCGA-D8-A1Y0 65 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.29 LumA European TCGA.D8.A1Y0.01A.11R.A14M.07
TCGA-D8-A1XO 56 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.3 LumA European TCGA.D8.A1XO.01A.11R.A14M.07
TCGA-AQ-A1H2 84 female White Primary solid Tumor postmenopausal IDC positive positive Indeterminate NA NA alive 1.3 LumA European TCGA.AQ.A1H2.01A.11R.A13Q.07
TCGA-BH-A0DP 60 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.3 LumA European TCGA.BH.A0DP.01A.21R.A056.07
TCGA-BH-A0DP 60 female White Solid Tissue Normal postmenopausal ILC positive positive negative NA NA alive 1.3 LumA European TCGA.BH.A0DP.11A.12R.A089.07
TCGA-BH-A0E1 52 female White Primary solid Tumor perimenopausal IDC positive positive equivocal NA NA alive 1.31 LumA European TCGA.BH.A0E1.01A.11R.A056.07
TCGA-BH-A0E1 52 female White Solid Tissue Normal perimenopausal IDC positive positive equivocal NA NA alive 1.31 LumA European TCGA.BH.A0E1.11A.13R.A089.07
TCGA-EW-A1J5 59 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.31 LumA European TCGA.EW.A1J5.01A.11R.A13Q.07
TCGA-LL-A73Y 67 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.31 Basal African TCGA.LL.A73Y.01A.11R.A33J.07
TCGA-E2-A3DX 43 female White Primary solid Tumor premenopausal ILC positive positive not evaluated NA NA alive 1.31 NA European TCGA.E2.A3DX.01A.21R.A213.07
TCGA-D8-A1JC 59 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.31 LumB European TCGA.D8.A1JC.01A.11R.A13Q.07
TCGA-D8-A1XR 56 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.32 LumB European TCGA.D8.A1XR.01A.11R.A14M.07
TCGA-A2-A0EY 62 female White Primary solid Tumor postmenopausal IDC positive negative positive NA NA alive 1.33 LumB European TCGA.A2.A0EY.01A.11R.A034.07
TCGA-E2-A14P 79 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 1.33 Her2 European TCGA.E2.A14P.01A.31R.A12D.07
TCGA-AR-A5QN 68 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 1.34 LumA European TCGA.AR.A5QN.01A.12R.A28M.07
TCGA-D8-A27F 40 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 1.34 Basal European TCGA.D8.A27F.01A.11R.A16F.07
TCGA-XX-A89A 68 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.34 LumA European TCGA.XX.A89A.01A.11R.A36F.07
TCGA-LL-A6FR 50 female Black or African American Primary solid Tumor postmenopausal IDC negative positive equivocal NA NA alive 1.34 Basal African TCGA.LL.A6FR.01A.12R.A31O.07
TCGA-D8-A73U 88 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.35 LumA European TCGA.D8.A73U.01A.11R.A33J.07
TCGA-BH-A0DZ 43 female White Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 1.36 LumA European TCGA.BH.A0DZ.01A.11R.A00Z.07
TCGA-BH-A0DZ 43 female White Solid Tissue Normal premenopausal IDC positive positive positive NA NA alive 1.36 LumA European TCGA.BH.A0DZ.11A.22R.A089.07
TCGA-A2-A25B 39 female Black or African American Primary solid Tumor premenopausal IDC positive positive equivocal metastasis bone alive 1.36 LumB African TCGA.A2.A25B.01A.11R.A169.07
TCGA-AC-A3HN 87 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.36 LumA European TCGA.AC.A3HN.01A.11R.A213.07
TCGA-D8-A1XQ 69 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.37 Basal European TCGA.D8.A1XQ.01A.11R.A14M.07
TCGA-D8-A27L 49 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.37 LumA European TCGA.D8.A27L.01A.11R.A16F.07
TCGA-A2-A1G6 50 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 1.37 Normal European TCGA.A2.A1G6.01A.11R.A13Q.07
TCGA-E2-A1BC 63 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.37 LumA European TCGA.E2.A1BC.01A.11R.A12P.07
TCGA-E2-A1BC 63 female not available Solid Tissue Normal postmenopausal IDC positive positive negative NA NA alive 1.37 LumA European TCGA.E2.A1BC.11A.32R.A12P.07
TCGA-D8-A1JA 60 female White Primary solid Tumor postmenopausal IDC negative negative positive locoregional disease NA alive 1.37 Her2 European TCGA.D8.A1JA.01A.11R.A13Q.07
TCGA-EW-A1J3 61 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 1.38 LumA European TCGA.EW.A1J3.01A.11R.A13Q.07
TCGA-D8-A1XT 61 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 1.39 Her2 European TCGA.D8.A1XT.01A.11R.A14M.07
TCGA-C8-A274 63 female Asian Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.39 LumB East Asian TCGA.C8.A274.01A.11R.A16F.07
TCGA-E9-A1N5 45 female White Primary solid Tumor postmenopausal IDC/ILC positive positive positive NA NA alive 1.39 NA European TCGA.E9.A1N5.01A.11R.A14D.07
TCGA-E9-A1N5 45 female White Solid Tissue Normal postmenopausal IDC/ILC positive positive positive NA NA alive 1.39 NA European TCGA.E9.A1N5.11A.41R.A14D.07
TCGA-EW-A6SA 59 male Black or African American Primary solid Tumor not applicable IDC positive negative negative NA NA alive 1.4 NA African TCGA.EW.A6SA.01A.21R.A32P.07
TCGA-BH-A0HN 67 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.41 NA European TCGA.BH.A0HN.01A.11R.A10U.07
TCGA-A8-A075 42 female not available Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 1.42 LumB European TCGA.A8.A075.01A.11R.A084.07
TCGA-A8-A0AB 54 female not available Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 1.42 LumA European TCGA.A8.A0AB.01A.11R.A034.07
TCGA-UL-AAZ6 73 female Black or African American Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 1.42 LumA African TCGA.UL.AAZ6.01A.11R.A41B.07
TCGA-D8-A27N 36 female White Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 1.42 LumB European TCGA.D8.A27N.01A.11R.A16F.07
TCGA-E2-A15R 64 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.42 LumA European TCGA.E2.A15R.01A.11R.A115.07
TCGA-LL-A5YL 64 female White Primary solid Tumor postmenopausal ILC positive negative positive NA NA alive 1.42 LumA European TCGA.LL.A5YL.01A.12R.A29R.07
TCGA-E2-A1BD 53 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.42 LumA European TCGA.E2.A1BD.01A.11R.A12P.07
TCGA-D8-A1XD 36 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.43 NA European TCGA.D8.A1XD.01A.11R.A14D.07
TCGA-A2-A25C 50 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.43 LumB European TCGA.A2.A25C.01A.11R.A169.07
TCGA-BH-A0DO 78 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.44 LumA European TCGA.BH.A0DO.01B.11R.A12D.07
TCGA-BH-A0DO 78 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA alive 1.44 LumA European TCGA.BH.A0DO.11A.22R.A12D.07
TCGA-S3-AA15 51 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.44 Basal African TCGA.S3.AA15.01A.11R.A41B.07
TCGA-E2-A15D 47 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 1.44 LumA European TCGA.E2.A15D.01A.11R.A115.07
TCGA-A2-A1FW 62 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 1.45 LumB European TCGA.A2.A1FW.01A.11R.A13Q.07
TCGA-OL-A66O 39 female Black or African American Primary solid Tumor premenopausal IDC positive positive not evaluated NA NA alive 1.45 LumA African TCGA.OL.A66O.01A.11R.A31O.07
TCGA-S3-AA14 47 female Black or African American Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 1.45 LumA African TCGA.S3.AA14.01A.11R.A41B.07
TCGA-D8-A27E 66 female White Primary solid Tumor postmenopausal IDC/mucinous positive positive negative NA NA alive 1.45 NA European TCGA.D8.A27E.01A.11R.A16F.07
TCGA-E2-A15I 44 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 1.45 LumA European TCGA.E2.A15I.01A.21R.A137.07
TCGA-E2-A15I 44 female White Solid Tissue Normal premenopausal IDC positive positive equivocal NA NA alive 1.45 LumA European TCGA.E2.A15I.11A.32R.A137.07
TCGA-A2-A0T5 39 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.45 LumA European TCGA.A2.A0T5.01A.21R.A084.07
TCGA-D8-A1J9 48 female White Primary solid Tumor postmenopausal IDC positive negative positive NA NA alive 1.46 LumB European TCGA.D8.A1J9.01A.11R.A13Q.07
TCGA-EW-A3U0 61 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.46 NA African_admix TCGA.EW.A3U0.01A.11R.A22K.07
TCGA-LL-A9Q3 69 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 1.46 LumA European TCGA.LL.A9Q3.01A.11R.A41B.07
TCGA-A2-A0T0 59 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.46 Basal European TCGA.A2.A0T0.01A.22R.A084.07
TCGA-D8-A1XM 57 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.47 LumA European TCGA.D8.A1XM.01A.21R.A14M.07
TCGA-AO-A1KT 78 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.48 LumB European TCGA.AO.A1KT.01A.11R.A13Q.07
TCGA-D8-A1X6 80 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.48 LumB European TCGA.D8.A1X6.01A.11R.A14M.07
TCGA-E9-A1N3 70 female White Primary solid Tumor postmenopausal IDC/ILC not evaluated not evaluated not evaluated NA NA alive 1.48 NA European TCGA.E9.A1N3.01A.12R.A157.07
TCGA-BH-A0W5 77 female White Primary solid Tumor not available IDC positive positive equivocal NA NA alive 1.49 LumA European TCGA.BH.A0W5.01A.11R.A109.07
TCGA-A7-A4SF 54 female Black or African American Primary solid Tumor postmenopausal IDC positive negative positive NA NA alive 1.49 NA African TCGA.A7.A4SF.01A.11R.A266.07
TCGA-A8-A093 61 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.49 LumA European TCGA.A8.A093.01A.11R.A00Z.07
TCGA-A8-A06R 69 female not available Primary solid Tumor postmenopausal IDC positive negative positive NA NA alive 1.5 LumB European TCGA.A8.A06R.01A.11R.A00Z.07
TCGA-A8-A082 58 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.5 LumB European TCGA.A8.A082.01A.11R.A00Z.07
TCGA-A8-A08F 59 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.5 NA European TCGA.A8.A08F.01A.11R.A00Z.07
TCGA-GM-A5PX 65 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.51 LumA European TCGA.GM.A5PX.01A.12R.A28M.07
TCGA-D8-A1JD 41 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.51 LumB European TCGA.D8.A1JD.01A.11R.A13Q.07
TCGA-D8-A1XB 62 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.51 LumA European TCGA.D8.A1XB.01A.11R.A14D.07
TCGA-A1-A0SQ 45 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.52 LumA European TCGA.A1.A0SQ.01A.21R.A144.07
TCGA-A2-A0YE 48 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.52 Basal European TCGA.A2.A0YE.01A.11R.A109.07
TCGA-BH-A0BD 47 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.52 LumB European TCGA.BH.A0BD.01A.11R.A034.07
TCGA-E2-A15G 76 female White Primary solid Tumor postmenopausal IDC/ILC positive positive negative NA NA alive 1.52 NA European TCGA.E2.A15G.01A.11R.A12D.07
TCGA-BH-A0W7 49 female White Primary solid Tumor not available IDC positive positive negative NA NA alive 1.53 LumA European TCGA.BH.A0W7.01A.11R.A115.07
TCGA-E9-A3Q9 78 female White Primary solid Tumor postmenopausal ILC positive positive Indeterminate NA NA alive 1.53 NA European TCGA.E9.A3Q9.01A.11R.A21T.07
TCGA-EW-A1P6 64 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.54 LumA European TCGA.EW.A1P6.01A.11R.A144.07
TCGA-S3-A6ZG 71 female Black or African American Primary solid Tumor postmenopausal IDC/ILC positive positive negative NA NA alive 1.54 NA African_admix TCGA.S3.A6ZG.01A.22R.A32P.07
TCGA-D8-A3Z6 56 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.54 LumA European TCGA.D8.A3Z6.01A.11R.A239.07
TCGA-D8-A1X5 81 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 1.55 LumB European TCGA.D8.A1X5.01A.11R.A14D.07
TCGA-A2-A0YJ 39 female White Primary solid Tumor premenopausal IDC positive negative negative metastasis cervical lymph node alive 1.55 Basal European TCGA.A2.A0YJ.01A.11R.A109.07
TCGA-AC-A6IV 47 female White Primary solid Tumor not available ILC positive positive equivocal NA NA alive 1.56 LumA European TCGA.AC.A6IV.01A.12R.A33J.07
TCGA-A2-A0T3 37 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 1.56 LumB European TCGA.A2.A0T3.01A.21R.A115.07
TCGA-D8-A1JB 54 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.56 LumA European TCGA.D8.A1JB.01A.11R.A13Q.07
TCGA-S3-A6ZF 64 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.57 LumB African TCGA.S3.A6ZF.01A.32R.A32P.07
TCGA-BH-A8FZ 58 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 1.57 Normal European TCGA.BH.A8FZ.01A.11R.A352.07
TCGA-E2-A1LG 50 female Black or African American Primary solid Tumor perimenopausal ILC negative negative equivocal NA NA alive 1.57 Basal African TCGA.E2.A1LG.01A.21R.A14M.07
TCGA-S3-AA12 82 female Black or African American Primary solid Tumor postmenopausal IDC positive negative negative metastasis lung|adrenal gland alive 1.57 LumA African TCGA.S3.AA12.01A.11R.A41B.07
TCGA-A2-A0T6 50 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 1.57 LumA European TCGA.A2.A0T6.01A.11R.A084.07
TCGA-D8-A1JE 62 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.57 LumB European TCGA.D8.A1JE.01A.11R.A13Q.07
TCGA-EW-A1PA 59 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.57 LumA European TCGA.EW.A1PA.01A.11R.A144.07
TCGA-E9-A1NH 71 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.58 LumA European TCGA.E9.A1NH.01A.11R.A14D.07
TCGA-A8-A07F 65 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.58 LumA European TCGA.A8.A07F.01A.11R.A00Z.07
TCGA-A8-A07G 65 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.58 LumA European TCGA.A8.A07G.01A.11R.A034.07
TCGA-D8-A1JI 54 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.58 LumB European TCGA.D8.A1JI.01A.11R.A13Q.07
TCGA-E2-A576 69 female Black or African American Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 1.58 LumA African TCGA.E2.A576.01A.11R.A31O.07
TCGA-A8-A09T 68 female not available Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.59 LumA European TCGA.A8.A09T.01A.11R.A00Z.07
TCGA-A8-A0A2 66 female not available Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.59 LumA European TCGA.A8.A0A2.01A.11R.A034.07
TCGA-A8-A07C 57 female not available Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.59 NA European TCGA.A8.A07C.01A.11R.A034.07
TCGA-A8-A08S 71 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 1.59 NA European TCGA.A8.A08S.01A.11R.A034.07
TCGA-A8-A091 61 female not available Primary solid Tumor postmenopausal IDC positive negative negative not available NA alive 1.59 LumA European TCGA.A8.A091.01A.11R.A00Z.07
TCGA-A1-A0SP 40 female not available Primary solid Tumor not available IDC negative negative negative NA NA alive 1.6 Basal European TCGA.A1.A0SP.01A.11R.A084.07
TCGA-A2-A1G1 85 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 1.6 Basal European TCGA.A2.A1G1.01A.21R.A13Q.07
TCGA-D8-A147 45 female White Primary solid Tumor indeterminate IDC negative negative negative NA NA alive 1.6 Basal European TCGA.D8.A147.01A.11R.A115.07
TCGA-AC-A23C 62 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 1.6 LumA European TCGA.AC.A23C.01A.12R.A169.07
TCGA-S3-AA10 65 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.6 Basal African TCGA.S3.AA10.01A.21R.A41B.07
TCGA-A2-A0YK 61 female White Primary solid Tumor postmenopausal ILC positive negative negative NA NA alive 1.61 Normal European TCGA.A2.A0YK.01A.22R.A109.07
TCGA-AC-A2QI 76 female White Primary solid Tumor postmenopausal ILC positive negative negative NA NA alive 1.61 NA European TCGA.AC.A2QI.01A.12R.A19W.07
TCGA-AC-A5XS 74 female White Primary solid Tumor not available ILC positive positive negative NA NA alive 1.61 LumA European TCGA.AC.A5XS.01A.11R.A29R.07
TCGA-D8-A1JM 59 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 1.62 Basal European TCGA.D8.A1JM.01A.11R.A13Q.07
TCGA-E2-A15J 51 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 1.62 LumA European TCGA.E2.A15J.01A.11R.A12P.07
TCGA-E2-A154 68 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.62 LumA European TCGA.E2.A154.01A.11R.A115.07
TCGA-LL-A7SZ 49 female Black or African American Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.63 LumA African TCGA.LL.A7SZ.01A.32R.A352.07
TCGA-A2-A1G4 71 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.63 LumB European TCGA.A2.A1G4.01A.11R.A13Q.07
TCGA-E2-A15P 61 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.63 LumA European TCGA.E2.A15P.01A.11R.A115.07
TCGA-LL-A8F5 61 female Black or African American Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 1.63 Basal African TCGA.LL.A8F5.01A.11R.A36F.07
TCGA-E2-A1L9 40 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.64 LumA European TCGA.E2.A1L9.01A.11R.A13Q.07
TCGA-D8-A1XL 34 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 1.66 LumB European TCGA.D8.A1XL.01A.11R.A14M.07
TCGA-A8-A08G 41 female not available Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 1.66 LumB European TCGA.A8.A08G.01A.11R.A00Z.07
TCGA-EW-A1PH 52 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.66 Basal European TCGA.EW.A1PH.01A.11R.A14M.07
TCGA-A8-A07E 81 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.66 LumA European TCGA.A8.A07E.01A.11R.A034.07
TCGA-EW-A1PB 70 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.66 Basal African TCGA.EW.A1PB.01A.11R.A144.07
TCGA-D8-A1JJ 54 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.67 LumB European TCGA.D8.A1JJ.01A.31R.A14M.07
TCGA-D8-A1JL 72 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.67 Basal European TCGA.D8.A1JL.01A.11R.A13Q.07
TCGA-BH-A2L8 45 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 1.68 LumA European TCGA.BH.A2L8.01A.11R.A18M.07
TCGA-AC-A8OP 72 female Black or African American Primary solid Tumor postmenopausal IDC positive positive Indeterminate NA NA alive 1.68 LumA African TCGA.AC.A8OP.01A.11R.A36F.07
TCGA-AR-A1AY 65 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.68 Basal European TCGA.AR.A1AY.01A.21R.A12P.07
TCGA-A2-A1G0 49 female White Primary solid Tumor premenopausal Infiltrating Tubulolobular Carcinoma positive positive equivocal NA NA alive 1.69 NA European TCGA.A2.A1G0.01A.11R.A13Q.07
TCGA-AO-A0J7 71 female White Primary solid Tumor postmenopausal ductal/mucinous positive positive negative NA NA alive 1.69 NA European TCGA.AO.A0J7.01A.11R.A034.07
TCGA-BH-A0HI 78 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.7 LumA European TCGA.BH.A0HI.01A.11R.A084.07
TCGA-D8-A1JN 80 female White Primary solid Tumor postmenopausal ILC positive positive Indeterminate NA NA alive 1.7 LumA European TCGA.D8.A1JN.01A.11R.A13Q.07
TCGA-OL-A5S0 66 female Black or African American Primary solid Tumor postmenopausal IDC positive negative not evaluated NA NA alive 1.7 Basal African_admix TCGA.OL.A5S0.01A.11R.A28M.07
TCGA-AO-A1KO 46 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 1.7 Normal European TCGA.AO.A1KO.01A.31R.A13Q.07
TCGA-AR-A5QP 54 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 1.7 LumA European TCGA.AR.A5QP.01A.11R.A28M.07
TCGA-BH-A0AW 56 female White Primary solid Tumor postmenopausal IDC positive negative positive NA NA alive 1.7 Her2 European TCGA.BH.A0AW.01A.11R.A056.07
TCGA-A2-A0T4 62 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 1.71 LumA European TCGA.A2.A0T4.01A.31R.A084.07
TCGA-D8-A141 40 female White Primary solid Tumor indeterminate IDC positive positive negative NA NA alive 1.71 LumA European TCGA.D8.A141.01A.11R.A115.07
TCGA-E2-A15L 65 female Black or African American Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 1.71 LumA African TCGA.E2.A15L.01A.11R.A12D.07
TCGA-E9-A1RH 63 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 1.71 Her2 European TCGA.E9.A1RH.01A.21R.A169.07
TCGA-E9-A1RH 63 female White Solid Tissue Normal postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 1.71 Her2 European TCGA.E9.A1RH.11A.34R.A169.07
TCGA-S3-AA0Z 63 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.72 Basal African TCGA.S3.AA0Z.01A.11R.A41B.07
TCGA-E2-A15E 40 female White Primary solid Tumor premenopausal IDC positive positive not evaluated NA NA alive 1.72 LumA European TCGA.E2.A15E.01A.11R.A12D.07
TCGA-E9-A22H 42 female White Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 1.72 LumB European_admix TCGA.E9.A22H.01A.11R.A157.07
TCGA-A2-A0T7 51 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.73 LumA European TCGA.A2.A0T7.01A.21R.A084.07
TCGA-A1-A0SI 52 female White Primary solid Tumor not available IDC positive positive negative NA NA alive 1.74 LumB European TCGA.A1.A0SI.01A.11R.A144.07
TCGA-A2-A3KC 55 female Black or African American Primary solid Tumor premenopausal ILC positive positive equivocal NA NA alive 1.74 NA African_admix TCGA.A2.A3KC.01A.11R.A213.07
TCGA-BH-A42V 41 female Black or African American Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.74 LumA African TCGA.BH.A42V.01A.11R.A24H.07
TCGA-D8-A13Z 51 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.74 Her2 European TCGA.D8.A13Z.01A.11R.A115.07
TCGA-D8-A1JP 73 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.75 LumA European TCGA.D8.A1JP.01A.11R.A13Q.07
TCGA-A8-A0A6 64 female not available Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.75 LumA European TCGA.A8.A0A6.01A.12R.A056.07
TCGA-E2-A155 58 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 1.75 LumB European TCGA.E2.A155.01A.11R.A12D.07
TCGA-S3-A6ZH 29 female Black or African American Primary solid Tumor unknown IDC positive positive equivocal NA NA alive 1.75 LumA African TCGA.S3.A6ZH.01A.22R.A32P.07
TCGA-A2-A0D0 60 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.76 Basal African TCGA.A2.A0D0.01A.11R.A00Z.07
TCGA-A2-A4S2 62 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.76 LumA European TCGA.A2.A4S2.01A.12R.A266.07
TCGA-D8-A146 57 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.76 NA European TCGA.D8.A146.01A.31R.A115.07
TCGA-A7-A4SE 54 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.76 Basal African TCGA.A7.A4SE.01A.11R.A266.07
TCGA-E9-A1R7 64 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 1.77 LumB European TCGA.E9.A1R7.01A.11R.A14M.07
TCGA-E9-A1R7 64 female White Solid Tissue Normal postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 1.77 LumB European TCGA.E9.A1R7.11A.42R.A14M.07
TCGA-LD-A66U 44 female White Primary solid Tumor not evaluated ILC positive positive negative NA NA alive 1.77 LumA European TCGA.LD.A66U.01A.11R.A31O.07
TCGA-E9-A1RG 62 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 1.77 LumB European TCGA.E9.A1RG.01A.11R.A14D.07
TCGA-EW-A3E8 60 female White Primary solid Tumor not evaluated ILC positive negative negative NA NA alive 1.77 NA European TCGA.EW.A3E8.01B.11R.A24H.07
TCGA-A2-A4RY 46 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 1.77 NA European TCGA.A2.A4RY.01A.31R.A266.07
TCGA-AO-A0JF 68 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.78 LumA European TCGA.AO.A0JF.01A.11R.A056.07
TCGA-AO-A0J3 67 female White Primary solid Tumor postmenopausal neuroendocrine and ductal positive positive equivocal NA NA alive 1.78 NA European TCGA.AO.A0J3.01A.11R.A034.07
TCGA-BH-A18H 63 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 1.79 LumA European TCGA.BH.A18H.01A.11R.A12D.07
TCGA-E9-A1NA 58 female White Primary solid Tumor postmenopausal IDC/ILC positive positive positive NA NA alive 1.79 NA European TCGA.E9.A1NA.01A.11R.A144.07
TCGA-E9-A1NA 58 female White Solid Tissue Normal postmenopausal IDC/ILC positive positive positive NA NA alive 1.79 NA European TCGA.E9.A1NA.11A.33R.A144.07
TCGA-AO-A0JA 36 female Black or African American Primary solid Tumor premenopausal IDC positive positive negative metastasis bone alive 1.79 LumA African_admix TCGA.AO.A0JA.01A.11R.A056.07
TCGA-E2-A15F 64 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.8 LumA European TCGA.E2.A15F.01A.11R.A115.07
TCGA-E2-A1IH 80 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 1.8 LumA European TCGA.E2.A1IH.01A.11R.A13Q.07
TCGA-A2-A0YH 53 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.8 LumB European TCGA.A2.A0YH.01A.11R.A109.07
TCGA-D8-A4Z1 68 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.8 LumA European TCGA.D8.A4Z1.01A.21R.A266.07
TCGA-E9-A1RE 74 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 1.8 LumB European TCGA.E9.A1RE.01A.11R.A157.07
TCGA-BH-A0BJ 41 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.81 LumA European TCGA.BH.A0BJ.01A.11R.A056.07
TCGA-BH-A0BJ 41 female White Solid Tissue Normal premenopausal IDC positive positive negative NA NA alive 1.81 LumA European TCGA.BH.A0BJ.11A.23R.A089.07
TCGA-A7-A26I 65 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 1.81 Basal European TCGA.A7.A26I.01A.11R.A169.07
TCGA-BH-A8G0 54 female White Primary solid Tumor perimenopausal ILC positive positive negative NA NA alive 1.81 LumA European TCGA.BH.A8G0.01A.11R.A352.07
TCGA-D8-A1XJ 76 female White Primary solid Tumor postmenopausal ductal/mucinous positive positive positive NA NA alive 1.82 NA European TCGA.D8.A1XJ.01A.11R.A14M.07
TCGA-AQ-A54O 51 male Black or African American Primary solid Tumor not applicable IDC positive positive negative NA NA alive 1.82 NA African TCGA.AQ.A54O.01A.11R.A266.07
TCGA-A2-A0YG 63 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 1.82 LumB European TCGA.A2.A0YG.01A.21R.A109.07
TCGA-A2-A4S3 59 female Black or African American Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.82 LumB African_admix TCGA.A2.A4S3.01A.21R.A266.07
TCGA-A2-A04U 47 female White Primary solid Tumor perimenopausal IDC negative negative negative NA NA alive 1.84 Basal European TCGA.A2.A04U.01A.11R.A115.07
TCGA-AC-A3QP 79 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 1.85 LumA European TCGA.AC.A3QP.01A.11R.A22U.07
TCGA-E2-A1IN 60 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.85 LumA European TCGA.E2.A1IN.01A.11R.A13Q.07
TCGA-AC-A2B8 84 female White Primary solid Tumor postmenopausal ILC positive positive negative new primary rectum alive 1.85 LumA European TCGA.AC.A2B8.01A.11R.A17B.07
TCGA-E2-A573 48 female Black or African American Primary solid Tumor perimenopausal IDC negative negative equivocal NA NA alive 1.85 Basal African TCGA.E2.A573.01A.11R.A29R.07
TCGA-A7-A2KD 53 female Black or African American Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 1.86 LumB African TCGA.A7.A2KD.01A.31R.A21T.07
TCGA-OL-A5RZ 57 female Black or African American Primary solid Tumor postmenopausal IDC positive negative not evaluated NA NA alive 1.86 Her2 African TCGA.OL.A5RZ.01A.11R.A28M.07
TCGA-AO-A0J8 61 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.86 LumA European TCGA.AO.A0J8.01A.21R.A034.07
TCGA-A2-A1FZ 63 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.87 LumA European TCGA.A2.A1FZ.01A.51R.A14D.07
TCGA-E2-A1IO 37 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 1.88 LumA European TCGA.E2.A1IO.01A.11R.A144.07
TCGA-E2-A1IK 71 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.89 LumA European TCGA.E2.A1IK.01A.11R.A144.07
TCGA-E9-A22B 71 female White Primary solid Tumor postmenopausal IDC/ILC positive negative negative NA NA alive 1.89 NA European TCGA.E9.A22B.01A.11R.A157.07
TCGA-E2-A15C 61 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 1.9 LumA European TCGA.E2.A15C.01A.31R.A12D.07
TCGA-EW-A1OW 58 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.9 NA African TCGA.EW.A1OW.01A.21R.A144.07
TCGA-BH-A0WA 82 female White Primary solid Tumor not available not available negative negative negative NA NA alive 1.92 NA European TCGA.BH.A0WA.01A.11R.A109.07
TCGA-A8-A08B 52 female not available Primary solid Tumor premenopausal IDC positive negative positive NA NA alive 1.92 Her2 European TCGA.A8.A08B.01A.11R.A00Z.07
TCGA-BH-A0H7 65 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.92 LumA European TCGA.BH.A0H7.01A.13R.A056.07
TCGA-BH-A0H7 65 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA alive 1.92 LumA European TCGA.BH.A0H7.11A.13R.A089.07
TCGA-EW-A1P5 77 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.92 LumA European TCGA.EW.A1P5.01A.11R.A144.07
TCGA-A2-A4S0 77 female White Primary solid Tumor postmenopausal mucinous carcinoma positive positive negative NA NA alive 1.93 NA European TCGA.A2.A4S0.01A.21R.A266.07
TCGA-AC-A3YI 74 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 1.94 Normal European TCGA.AC.A3YI.01A.21R.A239.07
TCGA-E2-A153 51 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.94 LumA European TCGA.E2.A153.01A.12R.A12D.07
TCGA-E2-A153 51 female White Solid Tissue Normal premenopausal IDC positive positive negative NA NA alive 1.94 LumA European TCGA.E2.A153.11A.31R.A12D.07
TCGA-E9-A1NC 61 female White Primary solid Tumor postmenopausal IDC/ILC negative positive positive NA NA alive 1.94 NA European TCGA.E9.A1NC.01A.21R.A26B.07
TCGA-AR-A0TU 35 female not available Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 1.94 NA European TCGA.AR.A0TU.01A.31R.A109.07
TCGA-E2-A15A 45 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 1.94 LumB European TCGA.E2.A15A.01A.11R.A12D.07
TCGA-GI-A2C9 58 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 1.95 NA African TCGA.GI.A2C9.01A.11R.A21T.07
TCGA-GI-A2C9 58 female Black or African American Solid Tissue Normal postmenopausal IDC negative negative negative NA NA alive 1.95 NA African TCGA.GI.A2C9.11A.22R.A21T.07
TCGA-BH-A0DG 30 female Black or African American Primary solid Tumor premenopausal IDC positive negative negative NA NA alive 1.95 LumA African TCGA.BH.A0DG.01A.21R.A12P.07
TCGA-BH-A0DG 30 female Black or African American Solid Tissue Normal premenopausal IDC positive negative negative NA NA alive 1.95 LumA African TCGA.BH.A0DG.11A.43R.A12P.07
TCGA-E9-A22A 74 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 1.95 LumB European TCGA.E9.A22A.01A.11R.A157.07
TCGA-A2-A1FV 74 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.95 LumA European TCGA.A2.A1FV.01A.11R.A13Q.07
TCGA-OL-A66I 36 female Black or African American Primary solid Tumor not evaluated IDC negative negative not evaluated NA NA alive 1.95 Basal African TCGA.OL.A66I.01A.21R.A29R.07
TCGA-BH-A5J0 63 female Black or African American Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.96 LumA African TCGA.BH.A5J0.01A.11R.A27Q.07
TCGA-E9-A22G 47 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 1.96 Basal European TCGA.E9.A22G.01A.11R.A157.07
TCGA-A7-A26G 50 female Black or African American Primary solid Tumor premenopausal IDC with Metaplastic features (area of sarcomatoid carcinoma) negative negative negative NA NA alive 1.98 NA African TCGA.A7.A26G.01A.21R.A169.07
TCGA-A7-A26H 72 female White Primary solid Tumor postmenopausal IDC positive negative equivocal not available NA alive 1.98 LumA European TCGA.A7.A26H.01A.11R.A169.07
TCGA-E9-A54Y 63 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 1.98 LumB European TCGA.E9.A54Y.01A.11R.A466.07
TCGA-E2-A156 61 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.99 LumA European TCGA.E2.A156.01A.11R.A12D.07
TCGA-BH-A0HF 77 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 1.99 NA European TCGA.BH.A0HF.01A.11R.A056.07
TCGA-D8-A1X9 66 female White Primary solid Tumor postmenopausal IDC positive positive Indeterminate NA NA alive 1.99 LumA European TCGA.D8.A1X9.01A.12R.A157.07
TCGA-E9-A54X 85 female White Primary solid Tumor postmenopausal mucinous carcinoma positive positive negative NA NA alive 1.99 NA European TCGA.E9.A54X.01A.11R.A266.07
TCGA-BH-A0W3 58 female White Primary solid Tumor indeterminate IDC positive positive equivocal NA NA alive 1.99 LumB European TCGA.BH.A0W3.01A.11R.A109.07
TCGA-A2-A0EU 79 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.01 LumA European TCGA.A2.A0EU.01A.22R.A056.07
TCGA-OL-A5RV 43 female Black or African American Primary solid Tumor premenopausal IDC positive positive not evaluated NA NA alive 2.01 LumA African TCGA.OL.A5RV.01A.12R.A28M.07
TCGA-AC-A3QQ 54 female White Primary solid Tumor perimenopausal ILC positive positive positive NA NA alive 2.01 LumA European TCGA.AC.A3QQ.01A.11R.A22K.07
TCGA-A7-A26F 55 female White Primary solid Tumor postmenopausal \adenocarcinoma with squamous differentiation, metaplastic\"" negative negative equivocal NA NA alive 2.02 NA European TCGA.A7.A26F.01A.21R.A169.07
TCGA-AR-A0TW 50 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 2.02 LumA European TCGA.AR.A0TW.01A.11R.A084.07
TCGA-A2-A4RX 67 female Black or African American Primary solid Tumor postmenopausal metaplastic carcinoma positive positive negative NA NA alive 2.03 NA African TCGA.A2.A4RX.01A.11R.A266.07
TCGA-BH-A0EI 51 female White Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 2.03 LumA European TCGA.BH.A0EI.01A.11R.A115.07
TCGA-GM-A3NY 72 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 2.03 NA European TCGA.GM.A3NY.01A.11R.A21T.07
TCGA-BH-A0EB 69 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 2.04 LumA European TCGA.BH.A0EB.01A.11R.A034.07
TCGA-BH-A0AU 45 female White Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 2.04 LumB European TCGA.BH.A0AU.01A.11R.A12P.07
TCGA-BH-A0AU 45 female White Solid Tissue Normal premenopausal IDC positive positive positive NA NA alive 2.04 LumB European TCGA.BH.A0AU.11A.11R.A12P.07
TCGA-BH-A0H6 82 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.05 LumA European TCGA.BH.A0H6.01A.21R.A056.07
TCGA-C8-A27A 48 female Asian Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 2.05 LumB East Asian TCGA.C8.A27A.01A.11R.A169.07
TCGA-E9-A24A 69 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 2.05 LumA European TCGA.E9.A24A.01A.11R.A169.07
TCGA-E2-A14V 53 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 2.05 Her2 European TCGA.E2.A14V.01A.11R.A12D.07
TCGA-A2-A0EX 46 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 2.06 LumA European TCGA.A2.A0EX.01A.21R.A034.07
TCGA-OL-A5RY 52 female Black or African American Primary solid Tumor postmenopausal IDC positive negative not evaluated NA NA alive 2.06 Normal African TCGA.OL.A5RY.01A.21R.A28M.07
TCGA-AC-A3YJ 66 female White Primary solid Tumor postmenopausal invasive papillary carcinoma positive positive not available NA NA alive 2.06 NA European TCGA.AC.A3YJ.01A.11R.A22U.07
TCGA-AQ-A04H 61 female White Primary solid Tumor postmenopausal IDC positive positive Indeterminate NA NA alive 2.06 LumB European TCGA.AQ.A04H.01B.11R.A10J.07
TCGA-E9-A1QZ 61 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 2.07 LumA European TCGA.E9.A1QZ.01A.21R.A169.07
TCGA-BH-A0BG 73 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 2.07 Basal European TCGA.BH.A0BG.01A.11R.A115.07
TCGA-BH-A0W4 46 female White Primary solid Tumor not available IDC positive positive negative NA NA alive 2.08 LumA European TCGA.BH.A0W4.01A.11R.A109.07
TCGA-LL-A440 61 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 2.08 LumA European TCGA.LL.A440.01A.11R.A24H.07
TCGA-A8-A07U 66 female not available Primary solid Tumor postmenopausal IDC negative positive negative NA NA alive 2.08 Basal European TCGA.A8.A07U.01A.11R.A034.07
TCGA-EW-A6SB 62 female Black or African American Primary solid Tumor not available IDC negative negative negative NA NA alive 2.08 Basal African TCGA.EW.A6SB.01A.12R.A32P.07
TCGA-A2-A0D2 45 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 2.08 Basal European TCGA.A2.A0D2.01A.21R.A034.07
TCGA-A8-A09Q 83 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.08 LumB European TCGA.A8.A09Q.01A.11R.A00Z.07
TCGA-LL-A50Y 84 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 2.09 LumA European TCGA.LL.A50Y.01A.11R.A266.07
TCGA-E2-A107 54 female White Primary solid Tumor postmenopausal ILC positive negative equivocal NA NA alive 2.09 LumA European TCGA.E2.A107.01A.11R.A10J.07
TCGA-A2-A04Y 53 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.09 LumB European TCGA.A2.A04Y.01A.21R.A034.07
TCGA-A7-A13F 44 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 2.09 LumB European TCGA.A7.A13F.01A.11R.A12P.07
TCGA-A7-A13F 44 female White Solid Tissue Normal premenopausal IDC positive positive equivocal NA NA alive 2.09 LumB European TCGA.A7.A13F.11A.42R.A12P.07
TCGA-A2-A0D4 37 female Black or African American Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 2.1 LumB African_admix TCGA.A2.A0D4.01A.11R.A00Z.07
TCGA-D8-A73X 53 female White Primary solid Tumor postmenopausal tubular carcinoma positive positive negative NA NA alive 2.1 NA European TCGA.D8.A73X.01A.11R.A32P.07
TCGA-A2-A0YD 63 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated NA NA alive 2.11 LumA European TCGA.A2.A0YD.01A.11R.A109.07
TCGA-E2-A150 48 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 2.12 Basal European TCGA.E2.A150.01A.11R.A12D.07
TCGA-AO-A0J6 61 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 2.12 Basal European TCGA.AO.A0J6.01A.11R.A034.07
TCGA-BH-A0AY 62 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.13 LumA European TCGA.BH.A0AY.01A.21R.A00Z.07
TCGA-BH-A0AY 62 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA alive 2.13 LumA European TCGA.BH.A0AY.11A.23R.A089.07
TCGA-D8-A1X8 62 female White Primary solid Tumor postmenopausal ILC positive Indeterminate negative NA NA alive 2.14 LumA European TCGA.D8.A1X8.01A.11R.A14M.07
TCGA-E9-A5UO 41 female White Primary solid Tumor premenopausal mucinous carcinoma not evaluated not evaluated not evaluated NA NA alive 2.15 NA European TCGA.E9.A5UO.01A.11R.A28M.07
TCGA-A2-A0D1 76 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 2.15 Her2 European TCGA.A2.A0D1.01A.11R.A034.07
TCGA-EW-A2FV 39 female White Primary solid Tumor premenopausal invasive micropapillary ductal carcinoma positive positive negative NA NA alive 2.16 NA European TCGA.EW.A2FV.01A.11R.A17B.07
TCGA-EW-A1OV 56 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 2.16 Her2 European TCGA.EW.A1OV.01A.11R.A144.07
TCGA-A8-A06Y 66 female not available Primary solid Tumor postmenopausal IDC positive positive negative not available not available alive 2.17 LumA European TCGA.A8.A06Y.01A.21R.A00Z.07
TCGA-OL-A66N 59 female White Primary solid Tumor postmenopausal ILC positive negative not evaluated NA NA alive 2.17 LumA European TCGA.OL.A66N.01A.12R.A31O.07
TCGA-E9-A3HO 49 female White Primary solid Tumor premenopausal ILC not evaluated not evaluated not evaluated NA NA alive 2.17 LumB European TCGA.E9.A3HO.01A.11R.A213.07
TCGA-BH-A202 60 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 2.18 LumB European TCGA.BH.A202.01A.11R.A14M.07
TCGA-OL-A5RW 40 female Black or African American Primary solid Tumor premenopausal IDC negative negative not evaluated NA NA alive 2.18 Basal African TCGA.OL.A5RW.01A.11R.A28M.07
TCGA-AO-A0JG 49 female White Primary solid Tumor postmenopausal ductal/mucinous positive positive negative NA NA alive 2.18 NA European TCGA.AO.A0JG.01A.31R.A084.07
TCGA-E9-A5UP 63 female White Primary solid Tumor postmenopausal infiltrating papillary adenocarcinoma not evaluated not evaluated not evaluated NA NA alive 2.2 NA European TCGA.E9.A5UP.01A.11R.A28M.07
TCGA-A2-A3KD 47 female White Primary solid Tumor premenopausal mucinous carcinoma positive positive negative NA NA alive 2.2 NA European TCGA.A2.A3KD.01A.12R.A213.07
TCGA-BH-A0HB 55 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 2.21 LumA European TCGA.BH.A0HB.01A.11R.A056.07
TCGA-A2-A0ET 58 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 2.21 LumA European TCGA.A2.A0ET.01A.31R.A034.07
TCGA-E2-A574 44 female Black or African American Primary solid Tumor premenopausal IDC negative negative equivocal NA NA alive 2.21 Basal African_admix TCGA.E2.A574.01A.11R.A29R.07
TCGA-E9-A5FK 60 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 2.22 LumA European TCGA.E9.A5FK.01A.11R.A27Q.07
TCGA-OL-A66H 74 female Black or African American Primary solid Tumor postmenopausal mucinous carcinoma positive positive not evaluated NA NA alive 2.22 NA African_admix TCGA.OL.A66H.01A.11R.A29R.07
TCGA-AQ-A04J 45 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 2.24 Basal European TCGA.AQ.A04J.01A.02R.A034.07
TCGA-A2-A4S1 66 female White Primary solid Tumor postmenopausal metaplastic carcinoma positive negative negative NA NA alive 2.25 Basal European TCGA.A2.A4S1.01A.21R.A266.07
TCGA-A8-A0A9 80 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.25 LumA European TCGA.A8.A0A9.01A.11R.A00Z.07
TCGA-E2-A152 56 female White Primary solid Tumor postmenopausal IDC positive negative positive metastasis liver>breast recur alive 2.26 Her2 European TCGA.E2.A152.01A.11R.A12D.07
TCGA-BH-A0BQ 39 female White Primary solid Tumor premenopausal IDC positive positive positive locoregional recurrence dermis|epidermis alive 2.26 LumA European TCGA.BH.A0BQ.01A.21R.A115.07
TCGA-BH-A0BQ 39 female White Solid Tissue Normal premenopausal IDC positive positive positive locoregional recurrence dermis|epidermis alive 2.26 LumA European TCGA.BH.A0BQ.11A.33R.A115.07
TCGA-E9-A247 59 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 2.27 LumA European TCGA.E9.A247.01A.11R.A169.07
TCGA-BH-A0HX 54 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.27 LumA European TCGA.BH.A0HX.01A.21R.A056.07
TCGA-E2-A572 72 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 2.28 NA African_admix TCGA.E2.A572.01A.13R.A31O.07
TCGA-E2-A14S 65 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 2.28 NA European TCGA.E2.A14S.01A.11R.A12D.07
TCGA-E2-A1L7 40 female White Primary solid Tumor premenopausal IDC negative negative negative new primary contralateral alive 2.28 LumB European TCGA.E2.A1L7.01A.11R.A144.07
TCGA-E2-A1L7 40 female White Solid Tissue Normal premenopausal IDC negative negative negative new primary contralateral alive 2.28 LumB European TCGA.E2.A1L7.11A.33R.A144.07
TCGA-E2-A108 64 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.29 Normal European TCGA.E2.A108.01A.13R.A10J.07
TCGA-E2-A14U 74 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 2.29 NA European_admix TCGA.E2.A14U.01A.11R.A22K.07
TCGA-E9-A1ND 75 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 2.29 Basal European TCGA.E9.A1ND.01A.11R.A144.07
TCGA-E9-A1ND 75 female White Solid Tissue Normal postmenopausal IDC negative negative positive NA NA alive 2.29 Basal European TCGA.E9.A1ND.11A.43R.A144.07
TCGA-D8-A1XA 64 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 2.3 LumA European TCGA.D8.A1XA.01A.11R.A14D.07
TCGA-OL-A5RU 63 female Black or African American Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA alive 2.3 LumA African TCGA.OL.A5RU.01A.11R.A28M.07
TCGA-AR-A2LR 49 female White Primary solid Tumor postmenopausal metaplastic carcinoma negative negative negative NA NA alive 2.32 NA European TCGA.AR.A2LR.01A.12R.A18M.07
TCGA-OL-A6VR 48 female Black or African American Primary solid Tumor unknown IDC positive positive negative NA NA alive 2.32 LumA African_admix TCGA.OL.A6VR.01A.32R.A33J.07
TCGA-LQ-A4E4 73 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated metastasis bone alive 2.32 NA European TCGA.LQ.A4E4.01A.11R.A266.07
TCGA-E2-A1II 51 female White Primary solid Tumor postmenopausal IDC negative positive negative NA NA alive 2.33 Basal European TCGA.E2.A1II.01A.11R.A144.07
TCGA-A1-A0SO 67 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 2.33 Basal European TCGA.A1.A0SO.01A.22R.A084.07
TCGA-A8-A07Z 85 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.34 LumA European TCGA.A8.A07Z.01A.11R.A00Z.07
TCGA-E2-A10C 54 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.34 LumB European TCGA.E2.A10C.01A.21R.A10J.07
TCGA-BH-A0HA 31 female White Primary solid Tumor premenopausal IDC positive positive not available NA NA alive 2.34 LumA European TCGA.BH.A0HA.01A.11R.A12P.07
TCGA-BH-A0HA 31 female White Solid Tissue Normal premenopausal IDC positive positive not available NA NA alive 2.34 LumA European TCGA.BH.A0HA.11A.31R.A12P.07
TCGA-BH-A201 64 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.34 LumA European TCGA.BH.A201.01A.11R.A14M.07
TCGA-OL-A6VO 43 female Black or African American Primary solid Tumor unknown IDC negative negative negative NA NA alive 2.35 Basal African_admix TCGA.OL.A6VO.01A.12R.A33J.07
TCGA-A2-A3Y0 57 female Black or African American Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 2.35 Basal African TCGA.A2.A3Y0.01A.11R.A239.07
TCGA-E9-A1R0 58 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA alive 2.35 LumA European TCGA.E9.A1R0.01A.22R.A16F.07
TCGA-AO-A12H 69 female Black or African American Primary solid Tumor premenopausal mucinous/papillary positive positive negative NA NA alive 2.36 NA African TCGA.AO.A12H.01A.11R.A115.07
TCGA-E2-A10E 64 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 2.37 NA European TCGA.E2.A10E.01A.21R.A10J.07
TCGA-E2-A1IJ 57 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 2.37 LumA European TCGA.E2.A1IJ.01A.11R.A144.07
TCGA-BH-A0AZ 47 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 2.37 LumA European TCGA.BH.A0AZ.01A.21R.A12P.07
TCGA-BH-A0AZ 47 female White Solid Tissue Normal premenopausal IDC positive positive negative NA NA alive 2.37 LumA European TCGA.BH.A0AZ.11A.22R.A12P.07
TCGA-E2-A1B6 44 female White Primary solid Tumor premenopausal IDC negative negative equivocal NA NA alive 2.37 Basal European TCGA.E2.A1B6.01A.31R.A12P.07
TCGA-BH-A0HY 60 female White Primary solid Tumor postmenopausal IDC positive negative positive NA NA alive 2.38 LumB European TCGA.BH.A0HY.01A.11R.A056.07
TCGA-E2-A14Y 35 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 2.38 Basal European TCGA.E2.A14Y.01A.21R.A12D.07
TCGA-A2-A0D3 42 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.4 LumA European TCGA.A2.A0D3.01A.11R.A115.07
TCGA-EW-A1PG 53 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 2.4 Normal European TCGA.EW.A1PG.01A.11R.A144.07
TCGA-E2-A10F 47 female White Primary solid Tumor premenopausal ILC positive positive equivocal NA NA alive 2.4 LumA European TCGA.E2.A10F.01A.11R.A10J.07
TCGA-OL-A5RX 51 female Black or African American Primary solid Tumor premenopausal IDC positive positive not evaluated NA NA alive 2.4 LumA African TCGA.OL.A5RX.01A.11R.A28M.07
TCGA-A8-A08C 65 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 2.41 NA European TCGA.A8.A08C.01A.11R.A00Z.07
TCGA-WT-AB44 77 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 2.42 LumA European TCGA.WT.AB44.01A.11R.A41B.07
TCGA-AO-A03V 41 female White Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 2.43 LumA European TCGA.AO.A03V.01A.11R.A115.07
TCGA-LL-A442 56 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 2.43 NA African TCGA.LL.A442.01A.11R.A24H.07
TCGA-AC-A4ZE 63 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 2.44 LumA European TCGA.AC.A4ZE.01A.11R.A41B.07
TCGA-E2-A14T 52 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.44 LumA European TCGA.E2.A14T.01A.11R.A115.07
TCGA-AR-A2LQ 59 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 2.45 Normal European TCGA.AR.A2LQ.01A.22R.A18M.07
TCGA-AR-A0TV 66 female not available Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 2.48 LumB European TCGA.AR.A0TV.01A.21R.A084.07
TCGA-EW-A1OY 63 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.49 LumB European TCGA.EW.A1OY.01A.11R.A144.07
TCGA-EW-A1OX 43 female White Primary solid Tumor premenopausal mucinous carcinoma positive positive negative NA NA alive 2.49 NA African_admix TCGA.EW.A1OX.01A.11R.A144.07
TCGA-A8-A09K 68 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.5 NA European TCGA.A8.A09K.01A.11R.A00Z.07
TCGA-BH-A0DI 63 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.5 LumA European TCGA.BH.A0DI.01A.21R.A12P.07
TCGA-E9-A22E 56 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 2.5 LumB European TCGA.E9.A22E.01A.11R.A157.07
TCGA-E9-A3QA 33 female White Primary solid Tumor premenopausal medullary carcinoma not evaluated not evaluated not evaluated NA NA alive 2.51 Basal European TCGA.E9.A3QA.01A.61R.A22K.07
TCGA-EW-A1P1 68 female White Primary solid Tumor postmenopausal IDC negative negative equivocal metastasis lung alive 2.52 Normal European TCGA.EW.A1P1.01A.31R.A14D.07
TCGA-BH-A0GY 67 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.53 LumA European TCGA.BH.A0GY.01A.11R.A056.07
TCGA-E9-A3X8 48 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA alive 2.54 LumA European TCGA.E9.A3X8.01A.31R.A22U.07
TCGA-A7-A0CJ 57 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.55 LumB European TCGA.A7.A0CJ.01A.21R.A00Z.07
TCGA-E2-A570 47 female Black or African American Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 2.55 LumA African TCGA.E2.A570.01A.11R.A29R.07
TCGA-A2-A1FX 61 female White Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA alive 2.56 LumB European TCGA.A2.A1FX.01A.11R.A13Q.07
TCGA-AR-A2LO 46 female White Primary solid Tumor premenopausal ILC positive positive equivocal NA NA alive 2.56 LumA European TCGA.AR.A2LO.01A.31R.A18M.07
TCGA-EW-A1OZ 56 female Black or African American Primary solid Tumor postmenopausal IDC positive negative equivocal NA NA alive 2.58 LumB African TCGA.EW.A1OZ.01A.11R.A144.07
TCGA-A8-A092 48 female not available Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 2.58 LumB European TCGA.A8.A092.01A.11R.A00Z.07
TCGA-A8-A08O 45 female not available Primary solid Tumor premenopausal IDC positive positive negative not available not available alive 2.58 LumA European TCGA.A8.A08O.01A.21R.A056.07
TCGA-A8-A08P 70 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 2.58 LumB European TCGA.A8.A08P.01A.11R.A00Z.07
TCGA-A8-A09E 73 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 2.58 NA European TCGA.A8.A09E.01A.11R.A00Z.07
TCGA-BH-A0EE 68 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 2.58 Her2 European TCGA.BH.A0EE.01A.11R.A034.07
TCGA-OL-A66L 71 female Black or African American Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA alive 2.59 LumA African TCGA.OL.A66L.01A.12R.A31O.07
TCGA-BH-A0DE 62 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.6 LumA European TCGA.BH.A0DE.01A.11R.A115.07
TCGA-EW-A6SC 60 female Black or African American Primary solid Tumor not available ILC positive positive negative NA NA alive 2.61 LumA African TCGA.EW.A6SC.01A.12R.A32P.07
TCGA-A7-A26E 71 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 2.61 LumA European TCGA.A7.A26E.01A.11R.A169.07
TCGA-E2-A1IF 74 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.62 LumA European TCGA.E2.A1IF.01A.11R.A144.07
TCGA-A2-A0YM 67 female White Primary solid Tumor postmenopausal IDC negative negative not evaluated NA NA alive 2.64 Basal European TCGA.A2.A0YM.01A.11R.A109.07
TCGA-A7-A13D 46 female Black or African American Primary solid Tumor postmenopausal IDC negative positive equivocal NA NA alive 2.64 Basal African TCGA.A7.A13D.01A.13R.A12P.07
TCGA-A2-A0EV 80 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.65 LumA European TCGA.A2.A0EV.01A.11R.A034.07
TCGA-E2-A14X 55 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 2.66 Basal African_admix TCGA.E2.A14X.01A.11R.A115.07
TCGA-E2-A1LB 41 female Black or African American Primary solid Tumor premenopausal IDC negative negative positive NA NA alive 2.66 Her2 African TCGA.E2.A1LB.01A.11R.A144.07
TCGA-E2-A1LB 41 female Black or African American Solid Tissue Normal premenopausal IDC negative negative positive NA NA alive 2.66 Her2 African TCGA.E2.A1LB.11A.22R.A144.07
TCGA-A2-A3XZ 46 female Black or African American Primary solid Tumor premenopausal IDC negative negative positive NA NA alive 2.66 Her2 African TCGA.A2.A3XZ.01A.42R.A239.07
TCGA-OL-A5D8 40 female Black or African American Primary solid Tumor premenopausal IDC positive positive not evaluated NA NA alive 2.66 LumA African TCGA.OL.A5D8.01A.11R.A27Q.07
TCGA-BH-A0BC 60 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.67 LumA European TCGA.BH.A0BC.01A.22R.A084.07
TCGA-BH-A0BC 60 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA alive 2.67 LumA European TCGA.BH.A0BC.11A.22R.A089.07
TCGA-E2-A14Q 50 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 2.67 LumA European TCGA.E2.A14Q.01A.11R.A12D.07
TCGA-E2-A14W 78 male White Primary solid Tumor not applicable IDC positive positive not evaluated NA NA alive 2.67 NA European TCGA.E2.A14W.01A.11R.A12D.07
TCGA-A8-A07L 58 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.67 LumB European TCGA.A8.A07L.01A.11R.A00Z.07
TCGA-E9-A1RA 48 female White Primary solid Tumor premenopausal IDC not evaluated not evaluated not evaluated NA NA alive 2.67 LumA European TCGA.E9.A1RA.01A.11R.A14D.07
TCGA-GM-A3XG 46 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 2.69 NA European TCGA.GM.A3XG.01A.31R.A24H.07
TCGA-E2-A1IE 61 female White Primary solid Tumor postmenopausal IDC positive positive equivocal metastasis liver alive 2.69 LumA European TCGA.E2.A1IE.01A.11R.A13Q.07
TCGA-E2-A1B5 46 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 2.69 LumA European TCGA.E2.A1B5.01A.21R.A12P.07
TCGA-AC-A3BB 46 female Black or African American Primary solid Tumor not available ILC positive positive negative NA NA alive 2.7 NA African TCGA.AC.A3BB.01A.21R.A19W.07
TCGA-EW-A1P3 48 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 2.7 LumA European TCGA.EW.A1P3.01A.11R.A144.07
TCGA-AQ-A1H3 49 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 2.71 LumA European TCGA.AQ.A1H3.01A.31R.A13Q.07
TCGA-A2-A0YC 59 female White Primary solid Tumor postmenopausal IDC positive positive not evaluated metastasis bone alive 2.71 LumA European TCGA.A2.A0YC.01A.11R.A109.07
TCGA-AR-A24W 55 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 2.71 LumA European TCGA.AR.A24W.01A.11R.A169.07
TCGA-A2-A3XV 46 female Black or African American Primary solid Tumor premenopausal IDC positive negative equivocal NA NA alive 2.73 Her2 African_admix TCGA.A2.A3XV.01A.21R.A239.07
TCGA-LL-A441 62 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 2.73 NA African TCGA.LL.A441.01A.11R.A24H.07
TCGA-AO-A0J2 41 female White Primary solid Tumor premenopausal IDC negative negative equivocal NA NA alive 2.73 Her2 European TCGA.AO.A0J2.01A.11R.A034.07
TCGA-AR-A2LN 65 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 2.73 LumA European TCGA.AR.A2LN.01A.21R.A18M.07
TCGA-E2-A1IG 45 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 2.73 LumA European TCGA.E2.A1IG.01A.11R.A144.07
TCGA-E2-A1IG 45 female White Solid Tissue Normal premenopausal IDC positive positive negative NA NA alive 2.73 LumA European TCGA.E2.A1IG.11A.22R.A144.07
TCGA-EW-A6SD 32 female Black or African American Primary solid Tumor not available IDC negative negative not evaluated NA NA alive 2.77 Her2 African TCGA.EW.A6SD.01A.12R.A33J.07
TCGA-BH-A0HQ 56 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 3.07 LumA European TCGA.BH.A0HQ.01A.11R.A034.07
TCGA-A8-A085 44 male not available Primary solid Tumor not applicable IDC positive positive negative NA NA alive 3.08 NA European TCGA.A8.A085.01A.11R.A00Z.07
TCGA-BH-A0BA 51 female White Primary solid Tumor premenopausal IDC/ILC positive positive negative NA NA alive 3.1 NA European TCGA.BH.A0BA.01A.11R.A056.07
TCGA-BH-A0BA 51 female White Solid Tissue Normal premenopausal IDC/ILC positive positive negative NA NA alive 3.1 NA European TCGA.BH.A0BA.11A.22R.A19E.07
TCGA-BH-A0B1 66 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 3.14 NA European TCGA.BH.A0B1.01A.12R.A056.07
TCGA-AR-A1AS 54 female Asian Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 3.15 LumA South Asian TCGA.AR.A1AS.01A.11R.A12P.07
TCGA-BH-A0DH 63 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 3.16 LumA European TCGA.BH.A0DH.01A.11R.A084.07
TCGA-BH-A0DH 63 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA alive 3.16 LumA European TCGA.BH.A0DH.11A.31R.A089.07
TCGA-A8-A0AD 83 female not available Primary solid Tumor postmenopausal IDC/ILC positive positive negative NA NA alive 3.17 NA European TCGA.A8.A0AD.01A.11R.A056.07
TCGA-BH-A0B4 65 male White Primary solid Tumor not applicable IDC positive positive equivocal NA NA alive 3.26 NA European TCGA.BH.A0B4.01A.11R.A00Z.07
TCGA-A1-A0SN 50 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 3.27 LumB European TCGA.A1.A0SN.01A.11R.A144.07
TCGA-BH-A0B3 53 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 3.29 Basal European TCGA.BH.A0B3.01A.11R.A056.07
TCGA-BH-A0B3 53 female White Solid Tissue Normal postmenopausal IDC negative negative negative NA NA alive 3.29 Basal European TCGA.BH.A0B3.11B.21R.A089.07
TCGA-EW-A1IX 48 female Asian Primary solid Tumor perimenopausal invasive tubulolobular carcinoma positive positive negative NA NA alive 3.31 NA East Asian TCGA.EW.A1IX.01A.12R.A144.07
TCGA-A8-A08Z 76 female not available Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 3.33 LumA European TCGA.A8.A08Z.01A.21R.A00Z.07
TCGA-E9-A1RC 56 female White Primary solid Tumor postmenopausal IDC/ILC not evaluated not evaluated not evaluated NA NA alive 3.35 NA European TCGA.E9.A1RC.01A.11R.A157.07
TCGA-E9-A1RC 56 female White Solid Tissue Normal postmenopausal IDC/ILC not evaluated not evaluated not evaluated NA NA alive 3.35 NA European TCGA.E9.A1RC.11A.33R.A157.07
TCGA-BH-A0H9 69 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 3.41 LumA European TCGA.BH.A0H9.01A.11R.A056.07
TCGA-BH-A0H9 69 female White Solid Tissue Normal postmenopausal IDC positive positive equivocal NA NA alive 3.41 LumA European TCGA.BH.A0H9.11A.22R.A466.07
TCGA-EW-A1P0 55 female White Primary solid Tumor postmenopausal IDC/mucinous positive negative negative metastasis mediastinal lymph node alive 3.43 NA European TCGA.EW.A1P0.01A.11R.A144.07
TCGA-BH-A0C0 62 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 3.48 LumB European TCGA.BH.A0C0.01A.21R.A056.07
TCGA-BH-A0C0 62 female White Solid Tissue Normal postmenopausal IDC positive positive equivocal NA NA alive 3.48 LumB European TCGA.BH.A0C0.11A.21R.A089.07
TCGA-A8-A095 45 female not available Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 3.5 LumB European TCGA.A8.A095.01A.11R.A00Z.07
TCGA-A8-A07B 69 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 3.58 LumA European TCGA.A8.A07B.01A.11R.A00Z.07
TCGA-A8-A08X 43 female not available Primary solid Tumor premenopausal IDC negative negative positive not available not available alive 3.58 Her2 European TCGA.A8.A08X.01A.21R.A00Z.07
TCGA-E2-A105 79 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 3.58 LumA European TCGA.E2.A105.01A.11R.A10J.07
TCGA-E2-A1LL 73 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative metastasis liver alive 3.58 Basal African_admix TCGA.E2.A1LL.01A.11R.A144.07
TCGA-A1-A0SE 56 female White Primary solid Tumor premenopausal IDC/ILC positive positive negative NA NA alive 3.62 NA European TCGA.A1.A0SE.01A.11R.A084.07
TCGA-B6-A1KC 67 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 3.63 LumB European TCGA.B6.A1KC.01B.11R.A157.07
TCGA-A2-A0SY 62 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated NA NA alive 3.69 LumA European TCGA.A2.A0SY.01A.31R.A084.07
TCGA-E2-A14O 76 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 3.72 LumB European TCGA.E2.A14O.01A.31R.A115.07
TCGA-BH-A0E7 79 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 3.73 LumA European TCGA.BH.A0E7.01A.11R.A034.07
TCGA-A8-A09I 84 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 3.75 LumB European TCGA.A8.A09I.01A.22R.A034.07
TCGA-E2-A109 64 female White Primary solid Tumor postmenopausal IDC positive negative equivocal NA NA alive 3.88 LumB European TCGA.E2.A109.01A.11R.A10J.07
TCGA-E2-A14N 37 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 3.93 Basal European TCGA.E2.A14N.01A.31R.A137.07
TCGA-A1-A0SH 39 female White Primary solid Tumor premenopausal IDC negative positive equivocal NA NA alive 3.93 LumA European TCGA.A1.A0SH.01A.11R.A084.07
TCGA-3C-AALK 52 female Black or African American Primary solid Tumor unknown IDC positive positive positive NA NA alive 3.96 LumA African TCGA.3C.AALK.01A.11R.A41B.07
TCGA-A1-A0SF 54 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 4.01 LumA European TCGA.A1.A0SF.01A.11R.A144.07
TCGA-5L-AAT1 63 female White Primary solid Tumor postmenopausal ILC positive positive equivocal metastasis bone alive 4.03 NA European TCGA.5L.AAT1.01A.12R.A41B.07
TCGA-3C-AALJ 62 female Black or African American Primary solid Tumor postmenopausal IDC positive positive Indeterminate NA NA alive 4.04 LumB African_admix TCGA.3C.AALJ.01A.31R.A41B.07
TCGA-C8-A12Y 44 female Asian Primary solid Tumor premenopausal IDC not evaluated not evaluated not evaluated NA NA alive 4.04 LumA East Asian TCGA.C8.A12Y.01A.11R.A12D.07
TCGA-BH-A0BV 78 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 4.16 LumA European TCGA.BH.A0BV.01A.11R.A00Z.07
TCGA-BH-A0BV 78 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA alive 4.16 LumA European TCGA.BH.A0BV.11A.31R.A089.07
TCGA-AO-A0JI 56 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 4.18 LumA European TCGA.AO.A0JI.01A.21R.A056.07
TCGA-A2-A0SX 48 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 4.2 Basal European TCGA.A2.A0SX.01A.12R.A084.07
TCGA-AO-A0JB 50 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 4.22 Normal European TCGA.AO.A0JB.01A.11R.A32Y.07
TCGA-AO-A0JC 64 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 4.24 LumA European TCGA.AO.A0JC.01A.11R.A056.07
TCGA-AR-A24K 46 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 4.24 LumB European TCGA.AR.A24K.01A.11R.A169.07
TCGA-BH-A0HW 62 female Asian Primary solid Tumor postmenopausal IDC positive negative equivocal NA NA alive 4.27 LumB East Asian TCGA.BH.A0HW.01A.11R.A034.07
TCGA-BH-A0B8 64 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 4.3 NA European TCGA.BH.A0B8.01A.21R.A056.07
TCGA-BH-A0B8 64 female White Solid Tissue Normal postmenopausal IDC positive positive equivocal NA NA alive 4.3 NA European TCGA.BH.A0B8.11A.41R.A089.07
TCGA-BH-A0B9 44 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 4.3 Basal European TCGA.BH.A0B9.01A.11R.A056.07
TCGA-A2-A259 70 female Black or African American Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 4.37 LumA African_admix TCGA.A2.A259.01A.11R.A16F.07
TCGA-EW-A2FS 41 female Black or African American Primary solid Tumor premenopausal IDC positive negative negative NA NA alive 4.39 LumA African TCGA.EW.A2FS.01A.11R.A17B.07
TCGA-WT-AB41 55 female Black or African American Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA alive 4.41 LumA African TCGA.WT.AB41.01A.11R.A41B.07
TCGA-AO-A0J9 61 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated metastasis bone alive 4.42 LumA European TCGA.AO.A0J9.01A.11R.A034.07
TCGA-A8-A06T 75 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 4.42 LumA European TCGA.A8.A06T.01A.11R.A00Z.07
TCGA-A2-A0CZ 46 female White Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 4.42 NA European TCGA.A2.A0CZ.01A.11R.A034.07
TCGA-BH-A0H5 45 female White Primary solid Tumor postmenopausal IDC positive positive not available NA NA alive 4.44 LumA European TCGA.BH.A0H5.01A.21R.A115.07
TCGA-BH-A0H5 45 female White Solid Tissue Normal postmenopausal IDC positive positive not available NA NA alive 4.44 LumA European TCGA.BH.A0H5.11A.62R.A115.07
TCGA-E2-A1B0 50 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 4.47 Her2 European TCGA.E2.A1B0.01A.11R.A12P.07
TCGA-AO-A12G 75 female White Primary solid Tumor postmenopausal pleomorphic ILC positive positive positive NA NA alive 4.49 NA European TCGA.AO.A12G.01A.11R.A10J.07
TCGA-A8-A076 66 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 4.5 LumB European TCGA.A8.A076.01A.21R.A00Z.07
TCGA-E2-A1L6 44 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 4.51 LumA European TCGA.E2.A1L6.01A.11R.A13Q.07
TCGA-A2-A0SU 66 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 4.55 LumA European TCGA.A2.A0SU.01A.11R.A084.07
TCGA-A2-A0CY 63 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 4.58 NA European TCGA.A2.A0CY.01A.12R.A034.07
TCGA-EW-A2FR 59 female Black or African American Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 4.58 Her2 South Asian TCGA.EW.A2FR.01A.11R.A21T.07
TCGA-AO-A0JL 59 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 4.61 NA European TCGA.AO.A0JL.01A.11R.A056.07
TCGA-A2-A04X 34 female White Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 4.62 Her2 European TCGA.A2.A04X.01A.21R.A034.07
TCGA-A2-A3XW 42 female Black or African American Primary solid Tumor premenopausal IDC positive negative negative NA NA alive 4.69 Normal African_admix TCGA.A2.A3XW.01A.11R.A239.07
TCGA-A2-A0CX 52 female White Primary solid Tumor premenopausal IDC positive negative positive NA NA alive 4.73 Her2 European TCGA.A2.A0CX.01A.21R.A00Z.07
TCGA-OL-A5D7 70 female Black or African American Primary solid Tumor postmenopausal IDC negative negative not evaluated NA NA alive 4.87 Basal African_admix TCGA.OL.A5D7.01A.11R.A27Q.07
TCGA-OL-A5DA 61 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated NA NA alive 4.88 LumA European TCGA.OL.A5DA.01A.11R.A27Q.07
TCGA-BH-A0AV 52 female Black or African American Primary solid Tumor not available IDC negative negative not available NA NA alive 4.98 Basal African_admix TCGA.BH.A0AV.01A.31R.A115.07
TCGA-AO-A12F 36 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 5.04 Basal European TCGA.AO.A12F.01A.11R.A115.07
TCGA-AC-A2FG 79 female White Primary solid Tumor postmenopausal ILC positive negative not evaluated NA NA alive 5.07 LumA European TCGA.AC.A2FG.01A.11R.A17B.07
TCGA-AR-A1AV 68 male White Primary solid Tumor not applicable IDC positive positive negative NA NA alive 5.1 NA European TCGA.AR.A1AV.01A.21R.A12P.07
TCGA-AO-A03M 29 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 5.11 LumA European TCGA.AO.A03M.01B.11R.A10J.07
TCGA-BH-A0BM 54 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 5.14 LumA European TCGA.BH.A0BM.01A.11R.A056.07
TCGA-BH-A0BM 54 female White Solid Tissue Normal postmenopausal IDC positive negative negative NA NA alive 5.14 LumA European TCGA.BH.A0BM.11A.12R.A089.07
TCGA-AO-A1KQ 84 male White Primary solid Tumor not applicable IDC positive positive negative NA NA alive 5.15 NA European TCGA.AO.A1KQ.01A.11R.A13Q.07
TCGA-AO-A0JJ 54 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 5.17 LumA European TCGA.AO.A0JJ.01A.11R.A056.07
TCGA-BH-A0H3 46 female White Primary solid Tumor premenopausal IDC positive positive not available NA NA alive 5.28 LumA European TCGA.BH.A0H3.01A.11R.A12P.07
TCGA-AR-A2LM 49 female White Primary solid Tumor premenopausal ILC positive positive not evaluated NA NA alive 5.3 LumA European TCGA.AR.A2LM.01A.11R.A180.07
TCGA-PE-A5DD 64 female Asian Primary solid Tumor postmenopausal ILC positive negative positive NA NA alive 5.35 LumA East Asian_admix TCGA.PE.A5DD.01A.12R.A27Q.07
TCGA-AR-A0TX 64 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 5.4 Her2 European TCGA.AR.A0TX.01A.11R.A084.07
TCGA-OL-A66J 80 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated NA NA alive 5.46 LumA European TCGA.OL.A66J.01A.11R.A29R.07
TCGA-GM-A3XN 44 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 5.53 NA European TCGA.GM.A3XN.01A.12R.A22U.07
TCGA-AO-A03N 59 female White Primary solid Tumor postmenopausal IDC positive positive negative locoregional disease NA alive 5.56 LumB European TCGA.AO.A03N.01B.11R.A10J.07
TCGA-V7-A7HQ 75 female Black or African American Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA alive 5.57 LumA African_admix TCGA.V7.A7HQ.01A.11R.A33J.07
TCGA-BH-A0DV 54 female White Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 5.65 LumA European TCGA.BH.A0DV.01A.21R.A12P.07
TCGA-BH-A0DV 54 female White Solid Tissue Normal perimenopausal IDC positive positive negative NA NA alive 5.65 LumA European TCGA.BH.A0DV.11A.22R.A12P.07
TCGA-B6-A408 55 female Black or African American Primary solid Tumor unknown IDC/ILC positive positive equivocal NA NA alive 5.67 NA African TCGA.B6.A408.01A.12R.A24H.07
TCGA-B6-A0RG 26 female White Primary solid Tumor indeterminate IDC negative negative not evaluated NA NA alive 5.7 LumA European TCGA.B6.A0RG.01A.11R.A056.07
TCGA-AO-A03R 57 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 5.72 Normal European TCGA.AO.A03R.01A.21R.A034.07
TCGA-GM-A3XL 49 female Black or African American Primary solid Tumor postmenopausal IDC negative negative not evaluated NA NA alive 5.77 Basal African TCGA.GM.A3XL.01A.11R.A22U.07
TCGA-AO-A03T 42 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 5.82 Normal European TCGA.AO.A03T.01A.21R.A034.07
TCGA-BH-A0B5 40 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 5.85 LumA European TCGA.BH.A0B5.01A.11R.A12P.07
TCGA-BH-A0B5 40 female White Solid Tissue Normal premenopausal ILC positive positive negative NA NA alive 5.85 LumA European TCGA.BH.A0B5.11A.23R.A12P.07
TCGA-AO-A12E 51 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 5.86 LumA European TCGA.AO.A12E.01A.11R.A10J.07
TCGA-GM-A2DF 53 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 5.9 Basal African TCGA.GM.A2DF.01A.11R.A180.07
TCGA-BH-A0DX 62 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 5.9 LumA European TCGA.BH.A0DX.01A.11R.A115.07
TCGA-AR-A255 62 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 5.92 LumA European TCGA.AR.A255.01A.11R.A169.07
TCGA-B6-A40C 51 female White Primary solid Tumor unknown ILC positive positive negative NA NA alive 5.92 LumA European TCGA.B6.A40C.01A.11R.A239.07
TCGA-A2-A0ES 52 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 6.0 LumA European TCGA.A2.A0ES.01A.11R.A115.07
TCGA-AO-A0JD 59 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 6.0 LumB European TCGA.AO.A0JD.01A.11R.A056.07
TCGA-GM-A4E0 67 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated NA NA alive 6.0 LumA European TCGA.GM.A4E0.01A.12R.A266.07
TCGA-GM-A2DH 58 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 6.0 Her2 European TCGA.GM.A2DH.01A.11R.A180.07
TCGA-BH-A0BO 54 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 6.02 LumA European TCGA.BH.A0BO.01A.23R.A12D.07
TCGA-AC-A2BK 78 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 6.08 Basal African TCGA.AC.A2BK.01A.11R.A21T.07
TCGA-B6-A1KI 63 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 6.12 LumA European TCGA.B6.A1KI.01A.11R.A14M.07
TCGA-E2-A1L8 52 female Black or African American Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 6.13 LumA African TCGA.E2.A1L8.01A.11R.A13Q.07
TCGA-A2-A04T 62 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 6.15 Basal European TCGA.A2.A04T.01A.21R.A034.07
TCGA-AC-A2FO 65 female White Primary solid Tumor postmenopausal ILC positive negative negative NA NA alive 6.17 LumA European TCGA.AC.A2FO.01A.11R.A180.07
TCGA-BH-A0BZ 59 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 6.17 LumB European TCGA.BH.A0BZ.01A.31R.A12P.07
TCGA-BH-A0BZ 59 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA alive 6.17 LumB European TCGA.BH.A0BZ.11A.61R.A12P.07
TCGA-A2-A0ER 63 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 6.2 LumA European TCGA.A2.A0ER.01A.21R.A034.07
TCGA-BH-A0BL 35 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 6.24 Basal European TCGA.BH.A0BL.01A.11R.A115.07
TCGA-B6-A402 47 female Black or African American Primary solid Tumor unknown IDC negative negative negative locoregional recurrence breast>lymph node alive 6.25 NA African TCGA.B6.A402.01A.11R.A239.07
TCGA-GM-A2DD 53 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 6.25 Normal European TCGA.GM.A2DD.01A.11R.A180.07
TCGA-A2-A0CT 71 female White Primary solid Tumor postmenopausal IDC positive negative equivocal NA NA alive 6.27 LumA European TCGA.A2.A0CT.01A.31R.A056.07
TCGA-E2-A1AZ 63 female White Primary solid Tumor postmenopausal IDC negative negative Indeterminate NA NA alive 6.38 Basal American TCGA.E2.A1AZ.01A.11R.A12P.07
TCGA-BH-A0BR 59 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 6.38 LumA European TCGA.BH.A0BR.01A.21R.A115.07
TCGA-AO-A0JE 53 female Black or African American Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 6.39 Her2 African TCGA.AO.A0JE.01A.11R.A056.07
TCGA-BH-A0BT 56 female White Primary solid Tumor not available IDC positive positive negative NA NA alive 6.48 LumA European TCGA.BH.A0BT.01A.11R.A12P.07
TCGA-BH-A0BT 56 female White Solid Tissue Normal not available IDC positive positive negative NA NA alive 6.48 LumA European TCGA.BH.A0BT.11A.21R.A12P.07
TCGA-AO-A12C 42 female White Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 6.49 NA European TCGA.AO.A12C.01A.11R.A10J.07
TCGA-BH-A0DL 64 female White Primary solid Tumor postmenopausal IDC with metaplastic carcinoma and focal apocrine features positive negative negative NA NA alive 6.52 NA European TCGA.BH.A0DL.01A.11R.A115.07
TCGA-BH-A0DL 64 female White Solid Tissue Normal postmenopausal IDC with metaplastic carcinoma and focal apocrine features positive negative negative NA NA alive 6.52 NA European TCGA.BH.A0DL.11A.13R.A115.07
TCGA-AR-A1AJ 83 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 6.52 Basal European TCGA.AR.A1AJ.01A.21R.A12P.07
TCGA-A2-A04Q 48 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 6.53 Basal European TCGA.A2.A04Q.01A.21R.A034.07
TCGA-BH-A0DT 41 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 6.58 LumA European TCGA.BH.A0DT.01A.21R.A12D.07
TCGA-BH-A0DT 41 female White Solid Tissue Normal premenopausal IDC positive positive negative NA NA alive 6.58 LumA European TCGA.BH.A0DT.11A.12R.A12D.07
TCGA-GM-A2DB 62 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 6.59 Her2 European TCGA.GM.A2DB.01A.31R.A18M.07
TCGA-A2-A0EQ 64 female Black or African American Primary solid Tumor postmenopausal IDC negative negative positive NA NA alive 6.64 Her2 African TCGA.A2.A0EQ.01A.11R.A034.07
TCGA-A2-A0EO 54 female White Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 6.69 LumA European TCGA.A2.A0EO.01A.11R.A034.07
TCGA-AO-A03L 34 female Asian Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 6.69 LumA South Asian_admix TCGA.AO.A03L.01A.41R.A056.07
TCGA-BH-A0B0 56 female Black or African American Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 6.78 LumA African_admix TCGA.BH.A0B0.01A.21R.A115.07
TCGA-BH-A0B6 47 female White Primary solid Tumor not available IDC positive positive positive NA NA alive 6.8 NA European TCGA.BH.A0B6.01A.11R.A19W.07
TCGA-BH-A0DD 58 male White Primary solid Tumor not applicable IDC positive positive positive NA NA alive 6.81 NA European TCGA.BH.A0DD.01A.31R.A12P.07
TCGA-BH-A0DD 58 male White Solid Tissue Normal not applicable IDC positive positive positive NA NA alive 6.81 NA European TCGA.BH.A0DD.11A.23R.A12P.07
TCGA-BH-A0E9 53 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 6.81 LumA European TCGA.BH.A0E9.01B.11R.A115.07
TCGA-AO-A1KR 51 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 6.88 Basal European TCGA.AO.A1KR.01A.12R.A144.07
TCGA-AO-A12D 43 female White Primary solid Tumor premenopausal IDC negative negative positive NA NA alive 6.89 Her2 European TCGA.AO.A12D.01A.11R.A115.07
TCGA-GM-A2DC 57 female White Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA alive 6.94 LumA European TCGA.GM.A2DC.01A.11R.A18M.07
TCGA-E2-A106 34 female Asian Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 6.96 NA East Asian TCGA.E2.A106.01A.11R.A10J.07
TCGA-AR-A0TS 46 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 7.0 Basal European TCGA.AR.A0TS.01A.11R.A115.07
TCGA-BH-A0B7 42 female White Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 7.01 Her2 European TCGA.BH.A0B7.01A.12R.A115.07
TCGA-BH-A0B7 42 female White Solid Tissue Normal premenopausal IDC positive positive positive NA NA alive 7.01 Her2 European TCGA.BH.A0B7.11A.34R.A115.07
TCGA-GM-A2DI 52 female White Primary solid Tumor premenopausal IDC negative negative not evaluated NA NA alive 7.09 LumA European TCGA.GM.A2DI.01A.31R.A18M.07
TCGA-B6-A401 47 female Black or African American Primary solid Tumor unknown IDC positive positive negative NA NA alive 7.11 LumA African_admix TCGA.B6.A401.01A.11R.A239.07
TCGA-GM-A2DO 54 female Black or African American Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 7.11 LumB African TCGA.GM.A2DO.01A.11R.A18M.07
TCGA-AR-A254 50 female White Primary solid Tumor premenopausal IDC positive positive positive NA NA alive 7.13 Her2 European TCGA.AR.A254.01A.21R.A169.07
TCGA-BH-A0BS 55 female White Primary solid Tumor postmenopausal IDC positive positive not available NA NA alive 7.15 LumA European TCGA.BH.A0BS.01A.11R.A12P.07
TCGA-BH-A0BS 55 female White Solid Tissue Normal postmenopausal IDC positive positive not available NA NA alive 7.15 LumA European TCGA.BH.A0BS.11A.11R.A12P.07
TCGA-AR-A1AO 47 female White Primary solid Tumor premenopausal IDC positive negative negative NA NA alive 7.17 Normal European TCGA.AR.A1AO.01A.11R.A12P.07
TCGA-AR-A1AX 64 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 7.2 LumA European TCGA.AR.A1AX.01A.11R.A12P.07
TCGA-AR-A1AW 65 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 7.21 LumB European TCGA.AR.A1AW.01A.21R.A12P.07
TCGA-AR-A2LJ 40 female White Primary solid Tumor premenopausal ILC positive positive positive NA NA alive 7.21 NA European TCGA.AR.A2LJ.01A.12R.A19W.07
TCGA-GM-A2DK 58 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 7.24 LumA European TCGA.GM.A2DK.01A.21R.A180.07
TCGA-PE-A5DE 41 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 7.24 LumA European TCGA.PE.A5DE.01A.11R.A27Q.07
TCGA-AC-A2FK 45 female White Primary solid Tumor not available ILC positive positive not evaluated NA NA alive 7.26 Normal American TCGA.AC.A2FK.01A.12R.A180.07
TCGA-E2-A1B1 45 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 7.26 LumA European TCGA.E2.A1B1.01A.21R.A12P.07
TCGA-A2-A0CQ 62 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 7.38 LumA African_admix TCGA.A2.A0CQ.01A.21R.A034.07
TCGA-AR-A250 58 female White Primary solid Tumor postmenopausal IDC positive negative equivocal NA NA alive 7.41 LumB European TCGA.AR.A250.01A.31R.A169.07
TCGA-BH-A0C3 47 female White Primary solid Tumor premenopausal with IDC/ILC phenotypes positive negative negative metastasis bone alive 7.42 NA European TCGA.BH.A0C3.01A.21R.A12P.07
TCGA-BH-A0C3 47 female White Solid Tissue Normal premenopausal with IDC/ILC phenotypes positive negative negative metastasis bone alive 7.42 NA European TCGA.BH.A0C3.11A.23R.A12P.07
TCGA-B6-A0RT 39 female White Primary solid Tumor indeterminate IDC negative negative not evaluated NA NA alive 7.45 Basal European TCGA.B6.A0RT.01A.21R.A084.07
TCGA-AC-A2FF 40 female Asian Primary solid Tumor not available ILC positive positive not evaluated NA NA alive 7.55 LumA South Asian_admix TCGA.AC.A2FF.01A.11R.A17B.07
TCGA-AC-A2FF 40 female Asian Solid Tissue Normal not available ILC positive positive not evaluated NA NA alive 7.55 LumA South Asian_admix TCGA.AC.A2FF.11A.13R.A17B.07
TCGA-BH-A0C7 48 female White Primary solid Tumor perimenopausal IDC positive negative not available NA NA alive 7.58 LumB European TCGA.BH.A0C7.01B.11R.A115.07
TCGA-A2-A3XT 45 female Black or African American Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 7.58 Basal African TCGA.A2.A3XT.01A.11R.A22U.07
TCGA-A2-A0CP 60 female White Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA alive 7.7 LumA European TCGA.A2.A0CP.01A.11R.A034.07
TCGA-AR-A252 50 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 7.77 LumA European TCGA.AR.A252.01A.11R.A169.07
TCGA-AR-A1AP 80 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 7.82 LumA European TCGA.AR.A1AP.01A.11R.A12P.07
TCGA-AR-A1AU 39 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 7.85 LumA European TCGA.AR.A1AU.01A.11R.A12P.07
TCGA-AR-A1AN 46 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 7.99 LumA European TCGA.AR.A1AN.01A.11R.A12P.07
TCGA-AO-A1KP 77 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 8.08 LumB European TCGA.AO.A1KP.01A.11R.A13Q.07
TCGA-AR-A1AL 60 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 8.13 LumA European TCGA.AR.A1AL.01A.21R.A12P.07
TCGA-AR-A24S 61 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 8.15 LumB European TCGA.AR.A24S.01A.11R.A169.07
TCGA-AR-A0TQ 27 female White Primary solid Tumor premenopausal IDC positive negative equivocal NA NA alive 8.19 LumB European TCGA.AR.A0TQ.01A.11R.A084.07
TCGA-AR-A1AM 52 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 8.19 NA European TCGA.AR.A1AM.01A.41R.A22K.07
TCGA-AR-A24Z 57 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 8.22 LumB European TCGA.AR.A24Z.01A.11R.A169.07
TCGA-AR-A24X 52 female White Primary solid Tumor premenopausal IDC/ILC positive positive equivocal NA NA alive 8.22 NA European TCGA.AR.A24X.01A.11R.A169.07
TCGA-A2-A0CV 41 female Asian Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 8.24 LumA East Asian TCGA.A2.A0CV.01A.31R.A115.07
TCGA-A2-A0CL 37 female Black or African American Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 8.25 Normal African TCGA.A2.A0CL.01A.11R.A115.07
TCGA-A2-A0ST 62 female White Primary solid Tumor postmenopausal IDC negative negative not evaluated NA NA alive 8.26 Basal European TCGA.A2.A0ST.01A.12R.A084.07
TCGA-AR-A1AQ 49 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 8.27 Basal European TCGA.AR.A1AQ.01A.11R.A12P.07
TCGA-AC-A2BM 41 female Black or African American Primary solid Tumor not available IDC positive positive not evaluated NA NA alive 8.27 LumB African TCGA.AC.A2BM.01A.11R.A21T.07
TCGA-AR-A251 51 female White Primary solid Tumor premenopausal IDC positive negative equivocal NA NA alive 8.3 Basal European TCGA.AR.A251.01A.12R.A169.07
TCGA-AR-A24N 54 female White Primary solid Tumor perimenopausal IDC positive positive equivocal NA NA alive 8.31 LumB European TCGA.AR.A24N.01A.11R.A169.07
TCGA-B6-A1KF 68 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 8.45 Basal European TCGA.B6.A1KF.01A.11R.A13Q.07
TCGA-GM-A2DN 58 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 8.46 LumA European TCGA.GM.A2DN.01A.11R.A180.07
TCGA-A2-A0EM 73 female White Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA alive 8.47 LumA European TCGA.A2.A0EM.01A.11R.A034.07
TCGA-A2-A04W 50 female White Primary solid Tumor premenopausal apocrine negative negative positive NA NA alive 8.49 NA European TCGA.A2.A04W.01A.31R.A115.07
TCGA-AO-A12A 47 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 8.52 LumA European TCGA.AO.A12A.01A.21R.A115.07
TCGA-E2-A1LI 57 female White Primary solid Tumor postmenopausal IDC negative negative equivocal NA NA alive 8.54 Basal European TCGA.E2.A1LI.01A.12R.A157.07
TCGA-AR-A24U 47 female White Primary solid Tumor premenopausal IDC negative negative positive NA NA alive 8.56 Her2 European TCGA.AR.A24U.01A.11R.A169.07
TCGA-B6-A40B 76 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 8.63 LumA European TCGA.B6.A40B.01A.11R.A239.07
TCGA-AR-A1AK 70 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 8.65 LumA European TCGA.AR.A1AK.01A.21R.A12P.07
TCGA-AR-A24Q 49 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 8.68 Basal European TCGA.AR.A24Q.01A.12R.A169.07
TCGA-AR-A24T 46 female White Primary solid Tumor premenopausal ILC positive positive equivocal NA NA alive 8.77 LumA European TCGA.AR.A24T.01A.11R.A169.07
TCGA-AR-A24V 52 female White Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 8.77 LumA European TCGA.AR.A24V.01A.21R.A169.07
TCGA-A2-A25E 34 female Black or African American Primary solid Tumor premenopausal IDC positive positive equivocal locoregional recurrence chest wall alive 8.77 LumB African TCGA.A2.A25E.01A.11R.A169.07
TCGA-GM-A2DM 57 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 8.83 LumA American TCGA.GM.A2DM.01A.11R.A180.07
TCGA-E2-A1LH 59 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 8.89 Basal European TCGA.E2.A1LH.01A.11R.A14D.07
TCGA-E2-A1LH 59 female White Solid Tissue Normal postmenopausal IDC negative negative negative NA NA alive 8.89 Basal European TCGA.E2.A1LH.11A.22R.A14D.07
TCGA-AO-A128 61 female White Primary solid Tumor postmenopausal IDC negative negative negative NA NA alive 8.89 Basal European TCGA.AO.A128.01A.11R.A10J.07
TCGA-Z7-A8R6 46 female White Primary solid Tumor premenopausal ILC positive positive negative NA NA alive 8.91 LumB European TCGA.Z7.A8R6.01A.11R.A41B.07
TCGA-AR-A0U4 54 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 8.93 Basal European TCGA.AR.A0U4.01A.11R.A109.07
TCGA-A2-A25A 44 female White Primary solid Tumor premenopausal ILC positive positive equivocal NA NA alive 8.97 Normal European TCGA.A2.A25A.01A.12R.A16F.07
TCGA-A2-A0CR 54 female Asian Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 8.99 LumA East Asian TCGA.A2.A0CR.01A.11R.A22K.07
TCGA-A2-A0CW 67 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA alive 8.99 LumB European TCGA.A2.A0CW.01A.21R.A115.07
TCGA-AO-A129 29 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA alive 9.0 Basal European TCGA.AO.A129.01A.21R.A10J.07
TCGA-Z7-A8R5 61 female White Primary solid Tumor postmenopausal ILC positive positive negative locoregional recurrence recur>bone alive 9.0 LumA European TCGA.Z7.A8R5.01A.42R.A41B.07
TCGA-AR-A1AI 47 female White Primary solid Tumor postmenopausal medullary carcinoma negative negative equivocal NA NA alive 9.02 Basal European TCGA.AR.A1AI.01A.11R.A12P.07
TCGA-AO-A126 39 female Asian Primary solid Tumor premenopausal IDC positive positive negative locoregional recurrence NA alive 9.05 LumA East Asian TCGA.AO.A126.01A.11R.A10J.07
TCGA-AR-A0TT 53 female Black or African American Primary solid Tumor premenopausal IDC positive negative negative NA NA alive 9.08 LumB African_admix TCGA.AR.A0TT.01A.31R.A084.07
TCGA-GM-A3NW 63 female White Primary solid Tumor postmenopausal ILC negative positive equivocal NA NA alive 9.2 LumA European TCGA.GM.A3NW.01A.21R.A22K.07
TCGA-BH-A42U 80 female Black or African American Primary solid Tumor postmenopausal ILC negative negative negative NA NA alive 9.21 Normal African TCGA.BH.A42U.01A.12R.A24H.07
TCGA-AR-A24R 45 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA alive 9.39 LumB European TCGA.AR.A24R.01A.11R.A169.07
TCGA-AO-A125 72 female Black or African American Primary solid Tumor postmenopausal papillary carcinoma positive positive negative NA NA alive 9.46 NA African TCGA.AO.A125.01A.11R.A10J.07
TCGA-AO-A124 38 female White Primary solid Tumor premenopausal mucinous/ductal negative negative negative NA NA alive 9.6 NA European TCGA.AO.A124.01A.11R.A10J.07
TCGA-GM-A2DL 50 female White Primary solid Tumor perimenopausal IDC positive positive negative NA NA alive 9.63 LumA European TCGA.GM.A2DL.01A.11R.A18M.07
TCGA-A2-A0EP 56 female White Primary solid Tumor postmenopausal ILC positive negative negative NA NA alive 9.86 LumA European TCGA.A2.A0EP.01A.52R.A22U.07
TCGA-AR-A24O 43 female White Primary solid Tumor premenopausal ILC with ductal features positive positive negative not available not available alive 9.88 NA European TCGA.AR.A24O.01A.11R.A169.07
TCGA-AR-A24M 38 female White Primary solid Tumor premenopausal IDC/ILC positive positive negative NA NA alive 10.02 NA European TCGA.AR.A24M.01A.11R.A169.07
TCGA-A2-A04R 36 female Black or African American Primary solid Tumor premenopausal IDC positive positive equivocal NA NA alive 10.15 LumB African_admix TCGA.A2.A04R.01A.41R.A109.07
TCGA-AR-A1AH 51 female White Primary solid Tumor postmenopausal IDC positive negative negative NA NA alive 10.42 Basal European TCGA.AR.A1AH.01A.11R.A12D.07
TCGA-AQ-A04L 48 female White Primary solid Tumor perimenopausal IDC positive negative positive NA NA alive 10.83 NA European TCGA.AQ.A04L.01B.21R.A10J.07
TCGA-3C-AALI 50 female Black or African American Primary solid Tumor postmenopausal IDC positive positive positive NA NA alive 10.97 Her2 African TCGA.3C.AALI.01A.11R.A41B.07
TCGA-3C-AAAU 55 female White Primary solid Tumor premenopausal ILC positive positive negative metastasis lung alive 11.08 LumA European TCGA.3C.AAAU.01A.11R.A41B.07
TCGA-AR-A0U3 59 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA alive 11.17 LumA European TCGA.AR.A0U3.01A.11R.A109.07
TCGA-A2-A0EN 70 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA alive 11.19 LumA European TCGA.A2.A0EN.01A.13R.A084.07
TCGA-A2-A0CK 60 female White Primary solid Tumor postmenopausal ILC positive positive negative new primary contralateral alive 11.39 LumA European TCGA.A2.A0CK.01A.11R.A22K.07
TCGA-B6-A1KN 57 female White Primary solid Tumor postmenopausal IDC negative negative not evaluated NA NA alive 11.59 LumB European TCGA.B6.A1KN.01A.11R.A13Q.07
TCGA-AR-A0TP 43 female White Primary solid Tumor premenopausal IDC positive negative negative NA NA alive 11.7 Basal European TCGA.AR.A0TP.01A.11R.A084.07
TCGA-B6-A0IQ 40 female White Primary solid Tumor indeterminate IDC negative negative not evaluated NA NA alive 11.73 Basal European TCGA.B6.A0IQ.01A.11R.A034.07
TCGA-A2-A04N 66 female White Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA alive 11.92 LumA European TCGA.A2.A04N.01A.11R.A115.07
TCGA-B6-A0I2 45 female White Primary solid Tumor indeterminate IDC not evaluated not evaluated not evaluated NA NA alive 11.94 Basal European TCGA.B6.A0I2.01A.11R.A034.07
TCGA-AR-A24H 65 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA alive 13.4 LumB European TCGA.AR.A24H.01A.11R.A169.07
TCGA-B6-A0RO 71 female White Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA alive 13.49 LumA European TCGA.B6.A0RO.01A.22R.A084.07
TCGA-B6-A0IO 66 female White Primary solid Tumor indeterminate IDC positive Indeterminate not evaluated NA NA alive 13.8 LumA European TCGA.B6.A0IO.01A.11R.A034.07
TCGA-AR-A2LE 69 female White Primary solid Tumor postmenopausal ILC positive negative not evaluated new primary endoometrium alive 13.86 LumA European TCGA.AR.A2LE.01A.11R.A180.07
TCGA-B6-A0RV 42 female White Primary solid Tumor indeterminate IDC/ILC positive positive not evaluated NA NA alive 14.12 NA European TCGA.B6.A0RV.01A.11R.A084.07
TCGA-B6-A0WT 61 female White Primary solid Tumor postmenopausal IDC positive positive not evaluated new primary contralateral alive 15.71 LumA European TCGA.B6.A0WT.01A.11R.A109.07
TCGA-B6-A0IJ 42 female Black or African American Primary solid Tumor indeterminate IDC positive positive not evaluated NA NA alive 19.46 Basal African TCGA.B6.A0IJ.01A.11R.A034.07
TCGA-B6-A0RI 44 female White Primary solid Tumor indeterminate IDC positive positive not evaluated locoregional disease chest wall alive 19.51 LumA European TCGA.B6.A0RI.01A.11R.A056.07
TCGA-B6-A0RE 61 female Black or African American Primary solid Tumor indeterminate IDC negative negative not evaluated NA NA alive 21.29 Basal African_admix TCGA.B6.A0RE.01A.11R.A056.07
TCGA-B6-A0RN 60 female White Primary solid Tumor postmenopausal IDC negative negative not evaluated NA NA alive 21.92 LumA European TCGA.B6.A0RN.01A.12R.A084.07
TCGA-B6-A0IA 51 female White Primary solid Tumor indeterminate ductal/cribiform positive positive not evaluated NA NA alive 22.97 NA European TCGA.B6.A0IA.01A.11R.A034.07
TCGA-B6-A0I5 49 female White Primary solid Tumor indeterminate IDC positive positive not evaluated NA NA alive 23.43 LumA European TCGA.B6.A0I5.01A.11R.A034.07
TCGA-B6-A0RU 40 female White Primary solid Tumor indeterminate ductal/metaplastic negative negative not evaluated NA NA alive 23.56 NA European TCGA.B6.A0RU.01A.11R.A084.07
TCGA-AC-A23H 90 female White Primary solid Tumor postmenopausal IDC positive negative positive NA NA dead NA Her2 European TCGA.AC.A23H.01A.11R.A157.07
TCGA-AC-A23H 90 female White Solid Tissue Normal postmenopausal IDC positive negative positive NA NA dead NA Her2 European TCGA.AC.A23H.11A.12R.A157.07
TCGA-E9-A1N6 52 female White Primary solid Tumor postmenopausal IDC positive positive positive metastasis bone>recur>liver dead NA NA European TCGA.E9.A1N6.01A.11R.A144.07
TCGA-E9-A1N6 52 female White Solid Tissue Normal postmenopausal IDC positive positive positive metastasis bone>recur>liver dead NA NA European TCGA.E9.A1N6.11A.32R.A144.07
TCGA-E9-A1NG 62 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA dead NA LumA European TCGA.E9.A1NG.01A.21R.A14M.07
TCGA-E9-A1NG 62 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA dead NA LumA European TCGA.E9.A1NG.11A.52R.A14M.07
TCGA-E9-A1NF 60 female White Primary solid Tumor postmenopausal IDC/ILC positive positive negative NA NA dead NA NA European TCGA.E9.A1NF.01A.11R.A14D.07
TCGA-E9-A1NF 60 female White Solid Tissue Normal postmenopausal IDC/ILC positive positive negative NA NA dead NA NA European TCGA.E9.A1NF.11A.73R.A14D.07
TCGA-C8-A3M7 60 female Asian Primary solid Tumor postmenopausal ILC negative negative negative locoregional recurrence NA dead 0.0 LumA East Asian TCGA.C8.A3M7.01A.12R.A21T.07
TCGA-AC-A62V 58 male Black or African American Primary solid Tumor not applicable IDC positive positive not evaluated metastasis bone dead 0.01 NA African TCGA.AC.A62V.01A.11R.A31O.07
TCGA-C8-A12Q 78 female Asian Primary solid Tumor postmenopausal IDC negative negative positive metastasis liver dead 0.01 Her2 East Asian TCGA.C8.A12Q.01A.11R.A115.07
TCGA-E9-A2JS 72 female White Primary solid Tumor postmenopausal ILC not evaluated not evaluated not evaluated metastasis bone|liver dead 0.04 LumB European TCGA.E9.A2JS.01A.11R.A180.07
TCGA-E9-A226 45 female White Primary solid Tumor premenopausal IDC not evaluated not evaluated not evaluated metastasis bone|liver dead 0.04 LumB European TCGA.E9.A226.01A.21R.A157.07
TCGA-AC-A3EH 79 female White Primary solid Tumor postmenopausal ILC positive negative negative NA NA dead 0.05 NA European TCGA.AC.A3EH.01A.22R.A22K.07
TCGA-E9-A1RB 40 female White Primary solid Tumor premenopausal IDC not evaluated not evaluated not evaluated NA NA dead 0.06 LumB European TCGA.E9.A1RB.01A.11R.A157.07
TCGA-E9-A1RB 40 female White Solid Tissue Normal premenopausal IDC not evaluated not evaluated not evaluated NA NA dead 0.06 LumB European TCGA.E9.A1RB.11A.33R.A157.07
TCGA-E9-A245 47 female White Primary solid Tumor premenopausal IDC not evaluated not evaluated not evaluated NA NA dead 0.07 LumA European TCGA.E9.A245.01A.22R.A16F.07
TCGA-A8-A08L 89 female not available Primary solid Tumor postmenopausal IDC positive negative negative NA NA dead 0.08 Her2 European TCGA.A8.A08L.01A.11R.A00Z.07
TCGA-BH-A42T 75 female Black or African American Primary solid Tumor postmenopausal ILC positive positive positive NA NA dead 0.88 NA African_admix TCGA.BH.A42T.01A.11R.A24H.07
TCGA-AC-A2QJ 48 female White Primary solid Tumor perimenopausal metaplastic carcinoma negative negative negative metastasis bone dead 1.22 NA American TCGA.AC.A2QJ.01A.12R.A19W.07
TCGA-D8-A1XC 85 female White Primary solid Tumor postmenopausal mucinous carcinoma positive positive negative metastasis bone dead 1.03 NA European TCGA.D8.A1XC.01A.11R.A14D.07
TCGA-D8-A1Y1 80 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA dead 0.83 LumB European TCGA.D8.A1Y1.01A.21R.A14M.07
TCGA-LL-A73Z 55 female Black or African American Primary solid Tumor postmenopausal IDC positive positive equivocal metastasis skin dead 0.62 Normal African TCGA.LL.A73Z.01A.11R.A32P.07
TCGA-A2-A0CU 73 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA dead 0.43 LumA European TCGA.A2.A0CU.01A.12R.A034.07
TCGA-E2-A15M 66 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA dead 0.92 LumA European TCGA.E2.A15M.01A.11R.A12D.07
TCGA-E2-A15M 66 female White Solid Tissue Normal postmenopausal ILC positive positive negative NA NA dead 0.92 LumA European TCGA.E2.A15M.11A.22R.A12D.07
TCGA-D8-A73W 79 female White Primary solid Tumor postmenopausal mucinous carcinoma positive negative negative metastasis lung|bone dead 1.05 NA European TCGA.D8.A73W.01A.22R.A352.07
TCGA-A2-A0T2 66 female White Primary solid Tumor postmenopausal IDC negative negative negative metastasis liver|abdomen dead 0.7 Basal European TCGA.A2.A0T2.01A.11R.A084.07
TCGA-AQ-A7U7 55 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA dead 1.6 LumA European TCGA.AQ.A7U7.01A.22R.A352.07
TCGA-E2-A2P5 78 female Black or African American Primary solid Tumor postmenopausal ILC positive positive not evaluated metastasis bone dead 2.25 NA admix TCGA.E2.A2P5.01A.11R.A19W.07
TCGA-OL-A5D6 71 female Black or African American Primary solid Tumor postmenopausal IDC negative negative not evaluated NA NA dead 3.02 Normal African_admix TCGA.OL.A5D6.01A.21R.A27Q.07
TCGA-E2-A14Z 64 female White Primary solid Tumor postmenopausal IDC positive positive negative metastasis bone dead 1.54 LumA European TCGA.E2.A14Z.01A.11R.A115.07
TCGA-A2-A04P 36 female Black or African American Primary solid Tumor premenopausal IDC negative negative not evaluated metastasis bone>axilla recur|lung>liver dead 1.5 Basal African TCGA.A2.A04P.01A.31R.A034.07
TCGA-A7-A13E 62 female White Primary solid Tumor postmenopausal IDC positive negative equivocal metastasis lung|bone|liver|brain|skin dead 1.68 Basal European TCGA.A7.A13E.01A.11R.A12P.07
TCGA-A7-A13E 62 female White Solid Tissue Normal postmenopausal IDC positive negative equivocal metastasis lung|bone|liver|brain|skin dead 1.68 Basal European TCGA.A7.A13E.11A.61R.A12P.07
TCGA-A2-A0YT 56 female White Primary solid Tumor postmenopausal IDC positive negative not evaluated NA NA dead 1.98 LumB European TCGA.A2.A0YT.01A.11R.A109.07
TCGA-AO-A0J5 48 female White Primary solid Tumor premenopausal ductal/micropapillary positive negative equivocal metastasis lung|bone|liver dead 2.17 NA European TCGA.AO.A0J5.01A.11R.A034.07
TCGA-A2-A0CM 40 female Black or African American Primary solid Tumor premenopausal IDC negative negative negative NA NA dead 2.06 Basal African_admix TCGA.A2.A0CM.01A.31R.A034.07
TCGA-A2-A0EW 53 female White Primary solid Tumor postmenopausal ILC positive positive negative metastasis bone dead 5.16 LumA European TCGA.A2.A0EW.01A.21R.A115.07
TCGA-BH-A0BF 56 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA dead 3.62 LumB European TCGA.BH.A0BF.01A.21R.A12P.07
TCGA-A2-A3XY 49 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative metastasis lung>lymph nodes>brain dead 2.99 NA African TCGA.A2.A3XY.01A.11R.A239.07
TCGA-AC-A2FE 62 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated NA bone>liver dead 7.22 NA European TCGA.AC.A2FE.01A.11R.A19W.07
TCGA-A2-A0SV 63 female White Primary solid Tumor postmenopausal IDC positive positive equivocal metastasis bone dead 2.26 LumB European TCGA.A2.A0SV.01A.11R.A084.07
TCGA-A8-A06U 80 female not available Primary solid Tumor postmenopausal IDC positive positive positive NA NA dead 2.42 LumA European TCGA.A8.A06U.01A.11R.A00Z.07
TCGA-E2-A1B4 74 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA dead 2.75 LumA European TCGA.E2.A1B4.01A.11R.A12P.07
TCGA-A2-A3XU 35 female Black or African American Primary solid Tumor postmenopausal IDC negative negative not evaluated metastasis bone>breast recur|chest wall dead 2.5 Basal African_admix TCGA.A2.A3XU.01A.12R.A22U.07
TCGA-A8-A06X 77 female not available Primary solid Tumor postmenopausal IDC positive negative positive NA NA dead 2.58 LumB European TCGA.A8.A06X.01A.21R.A00Z.07
TCGA-A1-A0SK 54 female Asian Primary solid Tumor indeterminate \neuroendocrine carcinoma, large-cell type, high-grade\"" negative negative negative NA NA dead 2.65 NA East Asian TCGA.A1.A0SK.01A.12R.A084.07
TCGA-OL-A66K 72 female White Primary solid Tumor postmenopausal ILC positive positive equivocal NA NA dead 3.49 LumA European TCGA.OL.A66K.01A.11R.A29R.07
TCGA-A2-A3XS 62 female Black or African American Primary solid Tumor postmenopausal IDC negative negative not evaluated metastasis lung dead 2.83 NA African_admix TCGA.A2.A3XS.01A.11R.A22U.07
TCGA-A8-A08J 52 female not available Primary solid Tumor postmenopausal IDC positive negative negative NA NA dead 3.09 Her2 European TCGA.A8.A08J.01A.11R.A00Z.07
TCGA-B6-A3ZX 50 female Black or African American Primary solid Tumor unknown IDC/ILC negative negative negative metastasis bone dead 3.15 NA African TCGA.B6.A3ZX.01A.11R.A239.07
TCGA-A2-A3XX 49 female Black or African American Primary solid Tumor postmenopausal IDC negative negative negative NA NA dead 3.94 Basal African TCGA.A2.A3XX.01A.21R.A239.07
TCGA-AR-A2LK 62 female White Primary solid Tumor postmenopausal ILC positive positive equivocal metastasis bone dead 4.51 LumB European TCGA.AR.A2LK.01A.11R.A180.07
TCGA-BH-A0C1 61 female White Primary solid Tumor postmenopausal ILC positive positive negative metastasis bone dead 3.86 LumA European TCGA.BH.A0C1.01B.11R.A12D.07
TCGA-A2-A0SW 82 female White Primary solid Tumor postmenopausal IDC positive negative not evaluated metastasis liver dead 3.74 LumB European TCGA.A2.A0SW.01A.11R.A084.07
TCGA-A2-A0CO 85 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA dead 4.02 NA European TCGA.A2.A0CO.01A.13R.A22K.07
TCGA-BH-A0BP 76 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA dead 6.29 LumA European TCGA.BH.A0BP.01A.11R.A115.07
TCGA-HN-A2OB 45 female not available Primary solid Tumor premenopausal ILC positive positive negative metastasis bone|omentum dead 5.2 LumA European TCGA.HN.A2OB.01A.21R.A27Q.07
TCGA-A2-A04V 39 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA dead 5.26 LumA European TCGA.A2.A04V.01A.21R.A034.07
TCGA-AR-A24L 26 female White Primary solid Tumor premenopausal IDC positive positive equivocal NA NA dead 7.85 LumA European TCGA.AR.A24L.01A.11R.A169.07
TCGA-AR-A0TZ 43 female White Primary solid Tumor premenopausal IDC positive positive equivocal metastasis bone dead 8.93 LumA European TCGA.AR.A0TZ.01A.12R.A084.07
TCGA-A2-A0CS 73 female White Primary solid Tumor postmenopausal IDC positive positive equivocal metastasis ovary dead 6.43 LumA European TCGA.A2.A0CS.01A.11R.A115.07
TCGA-AO-A03P 54 female Black or African American Primary solid Tumor postmenopausal IDC positive positive negative metastasis liver dead 7.97 LumB African TCGA.AO.A03P.01A.11R.A00Z.07
TCGA-B6-A0IP 74 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated NA NA dead 10.75 LumA European TCGA.B6.A0IP.01A.11R.A034.07
TCGA-A8-A08T 64 female not available Primary solid Tumor postmenopausal IDC positive positive positive not available not available dead 9.33 LumA European TCGA.A8.A08T.01A.21R.A00Z.07
TCGA-B6-A0IM 75 female Black or African American Primary solid Tumor postmenopausal ductal/cribiform positive positive not evaluated NA NA dead 10.6 NA African TCGA.B6.A0IM.01A.11R.A034.07
TCGA-B6-A0X1 48 female White Primary solid Tumor indeterminate IDC negative negative not evaluated NA NA dead 20.41 Basal European TCGA.B6.A0X1.01A.11R.A109.07
TCGA-B6-A0RH 51 female Black or African American Primary solid Tumor indeterminate IDC positive positive not evaluated NA NA dead 17.68 Her2 African TCGA.B6.A0RH.01A.21R.A115.07
TCGA-GM-A2DA 46 female White Primary solid Tumor postmenopausal IDC positive positive equivocal metastasis bone>liver>lymph node>brain dead 18.05 LumA European TCGA.GM.A2DA.01A.11R.A18M.07
TCGA-B6-A0IC 90 female White Primary solid Tumor postmenopausal invasive papillary positive positive not evaluated NA NA dead NA NA European TCGA.B6.A0IC.01A.11R.A034.07
TCGA-BH-A1F8 90 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA dead NA LumB European TCGA.BH.A1F8.01A.11R.A13Q.07
TCGA-BH-A1F8 90 female White Solid Tissue Normal postmenopausal IDC positive positive positive NA NA dead NA LumB European TCGA.BH.A1F8.11B.21R.A13Q.07
TCGA-UU-A93S 63 female Black or African American Primary solid Tumor postmenopausal IDC negative negative positive metastasis bone|liver dead 0.32 Her2 African_admix TCGA.UU.A93S.01A.21R.A41B.07
TCGA-AR-A0TR 68 female White Primary solid Tumor postmenopausal IDC positive positive equivocal NA NA dead 0.44 LumA European TCGA.AR.A0TR.01A.11R.A084.07
TCGA-AQ-A0Y5 70 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA dead 0.47 LumA European TCGA.AQ.A0Y5.01A.11R.A14M.07
TCGA-BH-A18T 70 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA dead 0.61 Basal European TCGA.BH.A18T.01A.11R.A12D.07
TCGA-EW-A1P8 58 female White Primary solid Tumor postmenopausal IDC negative negative negative metastasis lung|bone|liver|skin dead 0.65 Basal European TCGA.EW.A1P8.01A.11R.A144.07
TCGA-E2-A1LK 84 female Black or African American Primary solid Tumor postmenopausal IDC negative negative equivocal locoregional recurrence axilla dead 0.73 Basal African_admix TCGA.E2.A1LK.01A.21R.A14D.07
TCGA-BH-A8FY 87 female White Primary solid Tumor postmenopausal ILC positive positive negative NA NA dead 0.81 LumA European TCGA.BH.A8FY.01A.11R.A36F.07
TCGA-AR-A5QQ 68 female White Primary solid Tumor postmenopausal squamous (metaplastic) carcinoma negative negative negative locoregional recurrence chest wall|lung|liver|bone|adrenal glands dead 0.88 NA European TCGA.AR.A5QQ.01A.11R.A28M.07
TCGA-B6-A0I9 62 female White Primary solid Tumor indeterminate IDC Indeterminate positive not evaluated metastasis bone dead 0.99 Her2 European TCGA.B6.A0I9.01A.11R.A034.07
TCGA-BH-A1EV 45 female White Primary solid Tumor not available IDC positive positive positive NA NA dead 1.0 Her2 European TCGA.BH.A1EV.01A.11R.A137.07
TCGA-BH-A1EV 45 female White Solid Tissue Normal not available IDC positive positive positive NA NA dead 1.0 Her2 European TCGA.BH.A1EV.11A.24R.A137.07
TCGA-A8-A09X 62 female not available Primary solid Tumor postmenopausal ILC negative negative negative NA NA dead 1.17 Her2 European TCGA.A8.A09X.01A.11R.A00Z.07
TCGA-BH-A18N 88 female White Primary solid Tumor not available IDC positive positive negative NA NA dead 1.28 LumA European TCGA.BH.A18N.01A.11R.A12D.07
TCGA-BH-A18N 88 female White Solid Tissue Normal not available IDC positive positive negative NA NA dead 1.28 LumA European TCGA.BH.A18N.11A.43R.A12D.07
TCGA-AR-A1AR 50 female White Primary solid Tumor postmenopausal IDC negative negative negative new primary contralateral dead 1.43 Basal European TCGA.AR.A1AR.01A.31R.A137.07
TCGA-BH-A1EY 79 female White Primary solid Tumor postmenopausal IDC positive positive negative metastasis lung|liver dead 1.47 LumA European TCGA.BH.A1EY.01A.11R.A13Q.07
TCGA-B6-A0WW 58 female Black or African American Primary solid Tumor indeterminate IDC positive positive not evaluated metastasis brain dead 1.53 LumB African TCGA.B6.A0WW.01A.11R.A109.07
TCGA-B6-A0IK 63 female White Primary solid Tumor indeterminate IDC negative negative not evaluated metastasis lung dead 1.56 Her2 European TCGA.B6.A0IK.01A.12R.A056.07
TCGA-B6-A409 44 female Black or African American Primary solid Tumor premenopausal IDC negative negative equivocal metastasis lung dead 1.57 Basal African TCGA.B6.A409.01A.11R.A24H.07
TCGA-BH-A1FG 88 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA dead 1.58 LumA European TCGA.BH.A1FG.01A.11R.A13Q.07
TCGA-BH-A1FG 88 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA dead 1.58 LumA European TCGA.BH.A1FG.11B.12R.A13Q.07
TCGA-BH-A18J 56 female White Primary solid Tumor not available IDC positive positive negative metastasis bone dead 1.68 LumA European TCGA.BH.A18J.01A.11R.A12D.07
TCGA-BH-A18J 56 female White Solid Tissue Normal not available IDC positive positive negative metastasis bone dead 1.68 LumA European TCGA.BH.A18J.11A.31R.A12D.07
TCGA-AR-A2LH 55 female White Primary solid Tumor postmenopausal ILC negative negative equivocal metastasis bone|liver dead 1.69 Normal European TCGA.AR.A2LH.01A.31R.A18M.07
TCGA-B6-A0WX 40 female Black or African American Primary solid Tumor premenopausal pleomorphic/lobular negative negative not evaluated metastasis bone dead 1.75 NA African TCGA.B6.A0WX.01A.11R.A109.07
TCGA-B6-A0I8 46 female White Primary solid Tumor indeterminate IDC not evaluated not evaluated not evaluated locoregional disease pectoral muscle dead 2.05 NA European TCGA.B6.A0I8.01A.11R.A034.07
TCGA-BH-A1F0 80 female White Primary solid Tumor postmenopausal IDC negative Indeterminate negative NA NA dead 2.15 Basal European TCGA.BH.A1F0.01A.11R.A137.07
TCGA-BH-A1F0 80 female White Solid Tissue Normal postmenopausal IDC negative Indeterminate negative NA NA dead 2.15 Basal European TCGA.BH.A1F0.11B.23R.A137.07
TCGA-AC-A2FM 87 female White Primary solid Tumor postmenopausal ILC not evaluated not evaluated not evaluated metastasis bone marrow dead 2.17 NA European TCGA.AC.A2FM.01A.11R.A19W.07
TCGA-AC-A2FM 87 female White Solid Tissue Normal postmenopausal ILC not evaluated not evaluated not evaluated metastasis bone marrow dead 2.17 NA European TCGA.AC.A2FM.11B.32R.A19W.07
TCGA-BH-A18L 50 female White Primary solid Tumor not available IDC positive positive negative NA NA dead 2.22 LumB European TCGA.BH.A18L.01A.32R.A12D.07
TCGA-BH-A18L 50 female White Solid Tissue Normal not available IDC positive positive negative NA NA dead 2.22 LumB European TCGA.BH.A18L.11A.42R.A12D.07
TCGA-B6-A0X4 62 female White Primary solid Tumor postmenopausal IDC positive positive not evaluated metastasis bone dead 2.35 LumA European TCGA.B6.A0X4.01A.11R.A109.07
TCGA-E2-A1LE 71 female White Primary solid Tumor postmenopausal IDC negative negative positive metastasis lung dead 2.41 NA European TCGA.E2.A1LE.01A.12R.A19W.07
TCGA-BH-A18P 60 female White Primary solid Tumor not available IDC positive negative positive NA NA dead 2.52 Her2 European TCGA.BH.A18P.01A.11R.A12D.07
TCGA-BH-A18P 60 female White Solid Tissue Normal not available IDC positive negative positive NA NA dead 2.52 Her2 European TCGA.BH.A18P.11A.43R.A12D.07
TCGA-BH-A1F2 53 female White Primary solid Tumor not available IDC positive positive positive NA NA dead 2.63 LumB European TCGA.BH.A1F2.01A.31R.A13Q.07
TCGA-BH-A1F2 53 female White Solid Tissue Normal not available IDC positive positive positive NA NA dead 2.63 LumB European TCGA.BH.A1F2.11A.32R.A13Q.07
TCGA-B6-A0I6 49 female Black or African American Primary solid Tumor indeterminate IDC negative negative not evaluated metastasis bone|skin dead 2.71 NA African TCGA.B6.A0I6.01A.11R.A034.07
TCGA-BH-A0EA 72 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA dead 2.71 LumA European TCGA.BH.A0EA.01A.11R.A115.07
TCGA-BH-A1FD 68 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA dead 2.76 LumB European TCGA.BH.A1FD.01A.11R.A13Q.07
TCGA-BH-A1FD 68 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA dead 2.76 LumB European TCGA.BH.A1FD.11B.21R.A13Q.07
TCGA-BH-A1FH 47 female White Primary solid Tumor not available IDC positive negative not evaluated metastasis bone dead 2.83 LumA European TCGA.BH.A1FH.01A.12R.A13Q.07
TCGA-BH-A1FH 47 female White Solid Tissue Normal not available IDC positive negative not evaluated metastasis bone dead 2.83 LumA European TCGA.BH.A1FH.11B.42R.A13Q.07
TCGA-BH-A18R 50 female White Primary solid Tumor not available IDC Indeterminate negative positive NA NA dead 3.13 Her2 European TCGA.BH.A18R.01A.11R.A12D.07
TCGA-BH-A18R 50 female White Solid Tissue Normal not available IDC Indeterminate negative positive NA NA dead 3.13 Her2 European TCGA.BH.A18R.11A.42R.A12D.07
TCGA-BH-A203 78 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA dead 3.21 Her2 European TCGA.BH.A203.01A.12R.A169.07
TCGA-BH-A203 78 female White Solid Tissue Normal postmenopausal IDC not evaluated not evaluated not evaluated NA NA dead 3.21 Her2 European TCGA.BH.A203.11A.42R.A169.07
TCGA-AR-A1AT 62 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA dead 3.48 NA European TCGA.AR.A1AT.01A.11R.A12P.07
TCGA-BH-A1EU 83 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA dead 3.52 LumA European TCGA.BH.A1EU.01A.11R.A137.07
TCGA-BH-A1EU 83 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA dead 3.52 LumA European TCGA.BH.A1EU.11A.23R.A137.07
TCGA-BH-A1FM 44 female White Primary solid Tumor not available IDC positive negative not evaluated NA NA dead 3.8 LumB European TCGA.BH.A1FM.01A.11R.A13Q.07
TCGA-BH-A1FM 44 female White Solid Tissue Normal not available IDC positive negative not evaluated NA NA dead 3.8 LumB European TCGA.BH.A1FM.11B.23R.A13Q.07
TCGA-PE-A5DC 72 female White Primary solid Tumor postmenopausal ILC positive positive positive NA NA dead 3.92 LumA European TCGA.PE.A5DC.01A.12R.A27Q.07
TCGA-BH-A1EX 67 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA dead 4.13 LumA East Asian TCGA.BH.A1EX.01A.11R.A13Q.07
TCGA-BH-A18U 72 female White Primary solid Tumor postmenopausal IDC positive positive positive NA NA dead 4.28 LumB European TCGA.BH.A18U.01A.21R.A12D.07
TCGA-BH-A18U 72 female White Solid Tissue Normal postmenopausal IDC positive positive positive NA NA dead 4.28 LumB European TCGA.BH.A18U.11A.23R.A12D.07
TCGA-BH-A1FR 73 female White Primary solid Tumor not available IDC/mucinous positive positive not evaluated NA NA dead 4.5 NA European TCGA.BH.A1FR.01A.11R.A13Q.07
TCGA-BH-A1FR 73 female White Solid Tissue Normal not available IDC/mucinous positive positive not evaluated NA NA dead 4.5 NA European TCGA.BH.A1FR.11B.42R.A13Q.07
TCGA-BH-A1FL 69 female White Primary solid Tumor not available IDC positive positive not evaluated NA NA dead 4.58 LumA European TCGA.BH.A1FL.01A.11R.A13Q.07
TCGA-BH-A1FU 44 female White Primary solid Tumor not available IDC negative negative not evaluated NA NA dead 4.62 Normal European TCGA.BH.A1FU.01A.11R.A14D.07
TCGA-BH-A1FU 44 female White Solid Tissue Normal not available IDC negative negative not evaluated NA NA dead 4.62 Normal European TCGA.BH.A1FU.11A.23R.A14D.07
TCGA-BH-A18Q 56 female White Primary solid Tumor not available IDC negative negative positive NA NA dead 4.63 Basal European TCGA.BH.A18Q.01A.12R.A12D.07
TCGA-BH-A18Q 56 female White Solid Tissue Normal not available IDC negative negative positive NA NA dead 4.63 Basal European TCGA.BH.A18Q.11A.34R.A12D.07
TCGA-BH-A1EW 38 female White Primary solid Tumor premenopausal IDC negative negative negative NA NA dead 4.64 LumA European TCGA.BH.A1EW.01A.11R.A137.07
TCGA-BH-A1EW 38 female White Solid Tissue Normal premenopausal IDC negative negative negative NA NA dead 4.64 LumA European TCGA.BH.A1EW.11B.33R.A137.07
TCGA-AR-A0TY 54 female White Primary solid Tumor postmenopausal IDC positive negative negative metastasis bone dead 4.65 LumB European TCGA.AR.A0TY.01A.12R.A115.07
TCGA-BH-A208 48 female White Primary solid Tumor not available IDC not evaluated not evaluated not evaluated NA NA dead 4.82 Normal European TCGA.BH.A208.01A.11R.A157.07
TCGA-BH-A208 48 female White Solid Tissue Normal not available IDC not evaluated not evaluated not evaluated NA NA dead 4.82 Normal European TCGA.BH.A208.11A.51R.A157.07
TCGA-B6-A0X7 62 female White Primary solid Tumor postmenopausal IDC/ILC positive positive not evaluated new primary colon dead 4.88 NA European TCGA.B6.A0X7.01A.11R.A10J.07
TCGA-AO-A03U 31 female White Primary solid Tumor premenopausal secretory negative negative negative NA NA dead 4.91 NA European TCGA.AO.A03U.01B.21R.A10J.07
TCGA-GM-A2D9 69 female White Primary solid Tumor postmenopausal IDC positive positive not evaluated metastasis bone>lymph node|lung dead 4.96 LumA European TCGA.GM.A2D9.01A.11R.A18M.07
TCGA-BH-A1FJ 66 female White Primary solid Tumor not available IDC negative positive not evaluated NA NA dead 5.28 LumB European TCGA.BH.A1FJ.01A.11R.A13Q.07
TCGA-BH-A1FJ 66 female White Solid Tissue Normal not available IDC negative positive not evaluated NA NA dead 5.28 LumB European TCGA.BH.A1FJ.11B.42R.A13Q.07
TCGA-B6-A0IE 38 female Black or African American Primary solid Tumor premenopausal IDC/ILC negative negative not evaluated metastasis bone dead 5.46 NA African_admix TCGA.B6.A0IE.01A.11R.A034.07
TCGA-BH-A18S 79 female White Primary solid Tumor postmenopausal mucinous carcinoma positive positive negative NA NA dead 5.5 NA European TCGA.BH.A18S.01A.11R.A12D.07
TCGA-BH-A18S 79 female White Solid Tissue Normal postmenopausal mucinous carcinoma positive positive negative NA NA dead 5.5 NA European TCGA.BH.A18S.11A.43R.A12D.07
TCGA-B6-A0X5 61 female Black or African American Primary solid Tumor postmenopausal IDC positive positive not evaluated metastasis bone|liver|pleura dead 5.74 LumB African_admix TCGA.B6.A0X5.01A.21R.A109.07
TCGA-BH-A1EN 78 female White Primary solid Tumor postmenopausal IDC negative negative positive NA NA dead 5.82 Her2 European TCGA.BH.A1EN.01A.11R.A13Q.07
TCGA-BH-A1EN 78 female White Solid Tissue Normal postmenopausal IDC negative negative positive NA NA dead 5.82 Her2 European TCGA.BH.A1EN.11A.23R.A13Q.07
TCGA-BH-A1FN 34 female White Primary solid Tumor not available IDC positive positive not evaluated NA NA dead 6.0 LumB European TCGA.BH.A1FN.01A.11R.A13Q.07
TCGA-BH-A1FN 34 female White Solid Tissue Normal not available IDC positive positive not evaluated NA NA dead 6.0 LumB European TCGA.BH.A1FN.11A.34R.A13Q.07
TCGA-BH-A18M 39 female White Primary solid Tumor not available IDC positive positive positive NA NA dead 6.04 LumA European TCGA.BH.A18M.01A.11R.A12D.07
TCGA-BH-A18M 39 female White Solid Tissue Normal not available IDC positive positive positive NA NA dead 6.04 LumA European TCGA.BH.A18M.11A.33R.A12D.07
TCGA-BH-A1FE 31 female White Primary solid Tumor not available IDC positive positive not evaluated NA NA dead 6.22 LumA European TCGA.BH.A1FE.01A.11R.A13Q.07
TCGA-BH-A1FE 31 female White Solid Tissue Normal not available IDC positive positive not evaluated NA NA dead 6.22 LumA European TCGA.BH.A1FE.11B.14R.A13Q.07
TCGA-B6-A0I1 73 female Black or African American Primary solid Tumor postmenopausal IDC negative negative not evaluated metastasis lung dead 6.46 Basal African_admix TCGA.B6.A0I1.01A.11R.A21T.07
TCGA-B6-A0RM 57 female Black or African American Primary solid Tumor indeterminate IDC positive positive not evaluated NA NA dead 6.5 LumA African_admix TCGA.B6.A0RM.01A.11R.A084.07
TCGA-B6-A0WV 67 female White Primary solid Tumor postmenopausal IDC positive positive not evaluated NA NA dead 6.62 LumB European TCGA.B6.A0WV.01A.11R.A109.07
TCGA-B6-A0RL 60 female Black or African American Primary solid Tumor not available IDC positive positive not evaluated NA NA dead 6.76 LumB African TCGA.B6.A0RL.01A.11R.A084.07
TCGA-AO-A03O 69 female Black or African American Primary solid Tumor postmenopausal IDC positive positive negative NA NA dead 6.8 LumB African_admix TCGA.AO.A03O.01A.11R.A00Z.07
TCGA-BH-A1ET 55 female White Primary solid Tumor not available IDC positive positive negative NA NA dead 6.9 LumA European TCGA.BH.A1ET.01A.11R.A137.07
TCGA-BH-A1ET 55 female White Solid Tissue Normal not available IDC positive positive negative NA NA dead 6.9 LumA European TCGA.BH.A1ET.11B.23R.A137.07
TCGA-BH-A204 80 female White Primary solid Tumor postmenopausal IDC not evaluated not evaluated not evaluated NA NA dead 6.94 LumB European TCGA.BH.A204.01A.11R.A157.07
TCGA-BH-A204 80 female White Solid Tissue Normal postmenopausal IDC not evaluated not evaluated not evaluated NA NA dead 6.94 LumB European TCGA.BH.A204.11A.53R.A157.07
TCGA-AR-A0U2 47 female White Primary solid Tumor premenopausal IDC positive positive negative metastasis bone|liver dead 6.98 LumB European TCGA.AR.A0U2.01A.11R.A109.07
TCGA-B6-A0IN 45 female White Primary solid Tumor indeterminate IDC with mucinous features positive negative not evaluated metastasis bone|brain dead 7.04 NA European TCGA.B6.A0IN.01A.11R.A034.07
TCGA-BH-A1F5 62 female White Primary solid Tumor not available IDC positive positive negative NA NA dead 7.43 NA European TCGA.BH.A1F5.01A.12R.A13Q.07
TCGA-BH-A18K 46 female White Primary solid Tumor not available IDC positive positive negative NA NA dead 7.56 LumA European TCGA.BH.A18K.01A.11R.A12D.07
TCGA-BH-A18K 46 female White Solid Tissue Normal not available IDC positive positive negative NA NA dead 7.56 LumA European TCGA.BH.A18K.11A.13R.A12D.07
TCGA-BH-A1EO 68 female White Primary solid Tumor postmenopausal IDC/ILC features positive positive negative NA NA dead 7.66 NA European TCGA.BH.A1EO.01A.11R.A137.07
TCGA-BH-A1EO 68 female White Solid Tissue Normal postmenopausal IDC/ILC features positive positive negative NA NA dead 7.66 NA European TCGA.BH.A1EO.11A.31R.A137.07
TCGA-AR-A256 45 female White Primary solid Tumor premenopausal IDC negative negative negative locoregional disease NA dead 7.81 Basal European TCGA.AR.A256.01A.11R.A169.07
TCGA-B6-A0IH 81 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated NA NA dead 8.12 LumA European TCGA.B6.A0IH.01A.11R.A115.07
TCGA-B6-A0WS 58 female Black or African American Primary solid Tumor indeterminate IDC positive positive not evaluated NA NA dead 8.12 LumA African_admix TCGA.B6.A0WS.01A.11R.A115.07
TCGA-BH-A1F6 51 female White Primary solid Tumor not available IDC negative negative negative NA NA dead 8.12 Basal European TCGA.BH.A1F6.01A.11R.A13Q.07
TCGA-BH-A1F6 51 female White Solid Tissue Normal not available IDC negative negative negative NA NA dead 8.12 Basal European TCGA.BH.A1F6.11B.94R.A13Q.07
TCGA-B6-A0RS 38 female White Primary solid Tumor indeterminate IDC negative negative not evaluated new primary contralateral dead 8.39 Her2 European TCGA.B6.A0RS.01A.11R.A084.07
TCGA-B6-A0RP 73 female White Primary solid Tumor postmenopausal IDC/ILC positive positive not evaluated metastasis bone dead 8.56 NA European TCGA.B6.A0RP.01A.21R.A084.07
TCGA-B6-A0WY 40 female White Primary solid Tumor premenopausal IDC positive negative not evaluated metastasis bone dead 9.48 LumA European TCGA.B6.A0WY.01A.11R.A109.07
TCGA-BH-A1ES 35 female White Primary solid Tumor premenopausal IDC positive positive negative NA NA dead 9.48 NA European TCGA.BH.A1ES.01A.11R.A137.07
TCGA-BH-A1FC 78 female Black or African American Primary solid Tumor postmenopausal medullary carcinoma negative negative negative NA NA dead 9.51 Basal African TCGA.BH.A1FC.01A.11R.A13Q.07
TCGA-BH-A1FC 78 female Black or African American Solid Tissue Normal postmenopausal medullary carcinoma negative negative negative NA NA dead 9.51 Basal African TCGA.BH.A1FC.11A.32R.A13Q.07
TCGA-BH-A1FB 60 female White Primary solid Tumor postmenopausal IDC positive positive negative NA NA dead 10.05 NA European TCGA.BH.A1FB.01A.11R.A13Q.07
TCGA-BH-A1FB 60 female White Solid Tissue Normal postmenopausal IDC positive positive negative NA NA dead 10.05 NA European TCGA.BH.A1FB.11A.33R.A13Q.07
TCGA-B6-A0IB 64 female White Primary solid Tumor indeterminate IDC positive positive not evaluated metastasis skin>lung|bone|liver dead 10.79 LumB European TCGA.B6.A0IB.01A.11R.A034.07
TCGA-B6-A0X0 54 female White Primary solid Tumor indeterminate cribiform positive positive not evaluated NA NA dead 10.8 NA European TCGA.B6.A0X0.01A.21R.A115.07
TCGA-BH-A209 77 female Black or African American Primary solid Tumor postmenopausal medullary carcinoma positive positive not evaluated NA NA dead 10.84 LumB African TCGA.BH.A209.01A.11R.A157.07
TCGA-BH-A209 77 female Black or African American Solid Tissue Normal postmenopausal medullary carcinoma positive positive not evaluated NA NA dead 10.84 LumB African TCGA.BH.A209.11A.42R.A157.07
TCGA-B6-A0RQ 68 female White Primary solid Tumor postmenopausal ILC positive positive not evaluated NA NA dead 11.68 Normal European TCGA.B6.A0RQ.01A.11R.A115.07
TCGA-B6-A0IG 50 female White Primary solid Tumor indeterminate IDC positive positive not evaluated NA NA dead 12.2 LumA European TCGA.B6.A0IG.01A.11R.A034.07

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Breast Cancer Now is a company limited by guarantee registered in England (9347608) and a charity registered in England and Wales (1160558), Scotland (SC045584) and Isle of Man (1200). Registered Office: 6th Floor, The White Chapel Building, 10 Whitechapel High Street, London, England, E1 8QS.