BCNTB bioinformatics: the next evolutionary step in the bioinformatics of breast cancer tissue banking |
BCNB Research Environment; BCNB Analytics |
Informatics; Bioinformatics |
ICGC; TCGA; BCNB; CCLE |
2017 |
BCCTBbp: the Breast Cancer Campaign Tissue Bank bioinformatics portal |
BCNB Research Environment; BCNB Analytics |
Informatics; Bioinformatics |
TCGA |
2014 |
Single-cell RNA sequencing and spatial transcriptomics reveal cancer-associated fibroblasts in glioblastoma with protumoral effects |
Tumour Microenvironment |
Transcriptomics |
- |
2023 |
Aurora Kinase A Is an independent predictor of invasive recurrence in breast ductal carcinoma in situ |
Outcome; Tumour Progression & Metastasis |
Clinicopathologic; Protein Expression |
METABRIC |
2022 |
Breast cancer: Investment biobanking--increased returns from tissue samples |
Review |
Review |
- |
2013 |
Rare germline copy number variants (CNVs) and breast cancer risk |
Tumour Biology |
Genomics |
Breast Cancer Association Consortium (BCAC) |
2022 |
TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression |
Tumour Biology; Tumour Progression & Metastasis |
3D Model |
TCGA |
2023 |
Detection of involved margins in breast specimens with X-ray phase-contrast computed tomography |
Methods & Techniques |
X-ray Imaging Modalities |
- |
2021 |
Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer |
Molecular Subtypes; Outcome; Predictive Models; Early Detection |
Clinicopathologic; Proteomics; Transcriptomics |
TCGA |
2020 |
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway |
Lifestyle; Tumour Biology; Signalling Pathways |
Clinicopathologic |
- |
2020 |
A 3D in vitro model of the human breast duct: a method to unravel myoepithelial-luminal interactions in the progression of breast cancer |
Methods & Techniques |
Cell Culture; Microscopy |
- |
2017 |
Adding value to rare tissue samples donated to biobanks: characterisation of breast tissue and primary cell cultures obtained from a female-to-male transgender patient |
Internal QC |
Protein Expression |
- |
2014 |
Genomics England: Breast Cancer |
Informatics Research Environment |
Clinicopathologic; Genomics; Bioinformatics |
Genomics England |
2019 |
Role of IKK alpha in TNBC |
Signalling Pathways; Tumour Biology |
Protein Expression; Transcriptomics |
- |
2021 |
Dynamic biobanking for advancing breast cancer research |
Review; BCNB Research Environment |
Informatics; Bioinformatics; Clinicopathologic |
- |
2023 |
Characterization of the immune microenvironment in inflammatory breast cancer using multiplex immunofluorescence |
Tumour Microenvironment; Outcome |
Protein Expression |
- |
2023 |
The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples |
Tumour Biology; Predictive Models |
Epigenetics |
TCGA |
2022 |
Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock |
Methods & Techniques; Risk Assessments |
Epigenetics; Clinicopathologic |
- |
2022 |
Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women |
Clinical Trial |
Clinical Trial |
NCT01898312 |
2022 |
Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study |
Diversity & Equality; Lifestyle; Predictive Models |
Clinicopathologic; Genomics |
UKBiobank; Breast Cancer Association Consortium (BCAC) |
2022 |
Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival |
Tumour Microenvironment; Tumour Progression & Metastasis; Early Detection; Signalling Pathways; Outcome |
Protein Expression; Transcriptomics |
GenExMiner; METABRIC; TCGA |
2020 |
Field cancerization in breast cancer |
Tumour Biology; Early Detection; Review |
Review |
- |
2022 |
Incorporating progesterone receptor expression into the PREDICT breast prognostic model |
Methods & Techniques; Early Detection |
Bioinformatics |
Breast Cancer Association Consortium (BCAC) |
2022 |
Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion |
Tumour Progression & Metastasis |
Protein Expression |
- |
2022 |
Pin1 plays a key role in the response to treatment and clinical outcome in triple negative breast cancer |
Tumour Biology; Drug Response |
Protein Expression; Transcriptomics |
- |
2020 |
Cancer-associated fibroblasts induce an aggressive phenotypic shift in non-malignant breast epithelial cells via interleukin-8 and S100A8 |
Tumour Microenvironment; Tumour Biology |
Mouse Model; Protein Expression |
- |
2021 |
MicroRNA-495/TGF-β/FOXC1 axis regulates multidrug resistance in metaplastic breast cancer cells |
Drug Response; Outcome; Tumour Biology |
Epigenetics; Transcriptomics |
- |
2021 |
Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors |
Tumour Biology |
Mouse Model; Microscopy; Transcriptomics |
- |
2021 |
Tumor-infiltrating B lymphocyte profiling identifies IgG-biased, clonally expanded prognostic phenotypes in triple-negative breast cancer |
Clonal Dynamics; Outcome; Molecular Subtypes |
Protein Expression; Transcriptomics |
TCGA |
2021 |
PPFIA1 expression associates with poor response to endocrine treatment in luminal breast cancer |
Tumour Progression & Metastasis; Tumour Biology; Drug Response |
Protein Expression; Transcriptomics |
GenExMiner; METABRIC |
2020 |
CAFs and cancer cells co-Migration in 3D spheroid invasion assay |
Tumour Microenvironment; Methods & Techniques |
Cell Culture |
- |
2020 |
Clinicopathological significance of lipocalin 2 nuclear expression in invasive breast cancer |
Tumour Progression & Metastasis; Outcome |
Clinicopathologic; Protein Expression |
TCGA |
2019 |
Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer |
Outcome; Tumour Biology |
Protein Expression; Transcriptomics |
METABRIC |
2020 |
Enhanced glutamine uptake influences composition of immune cell infiltrates in breast cancer |
Tumour Progression & Metastasis |
Protein Expression |
- |
2020 |
Stromal NRG1 in luminal breast cancer defines pro-fibrotic and migratory cancer-associated fibroblasts |
Tumour Progression & Metastasis; Drug Resistance; Tumour Microenvironment |
Protein Expression; Transcriptomics |
- |
2021 |
Cytoplasmic cyclin E Is an independent marker of aggressive tumor biology and breast cancer-specific mortality in women over 70 years of age |
Tumour Biology; Outcome |
Clinicopathologic; Protein Expression |
- |
2020 |
Co-expression effect of SLC7A5/SLC3A2 to predict response to endocrine therapy in oestrogen-receptor-positive breast cancer |
Drug Resistance |
Protein Expression; Transcriptomics |
METABRIC |
2020 |
SOX11 promotes epithelial/mesenchymal hybrid state and alters tropism of invasive breast cancer cells |
Tumour Progression & Metastasis; Outcome |
Mouse Model; Protein Expression |
- |
2020 |
Werner Syndrome Protein Expression in Breast Cancer |
Outcome |
Clinicopathologic; Protein Expression |
- |
2021 |
The prognostic significance of wild-type isocitrate dehydrogenase 2 (IDH2) in breast cancer |
Outcome |
Clinicopathologic; Protein Expression; Transcriptomics |
METABRIC; TCGA |
2019 |
The solute carrier SLC7A8 is a marker of favourable prognosis in ER-positive low proliferative invasive breast cancer |
Prognostic Assessments; Molecular Subtypes |
Genomics; Protein Expression; Transcriptomics |
METABRIC |
2020 |
IL6/STAT3 signaling hijacks estrogen receptor α enhancers to drive breast cancer metastasis |
Tumour Progression & Metastasis; Signalling Pathways |
Mouse Model; Proteomics; Transcriptomics |
- |
2020 |
Integrated analysis of key differentially expressed genes identifies DBN1 as a predictive marker of response to endocrine therapy in luminal breast cancer |
Drug Response; Outcome; Prognostic Assessments |
Clinicopathologic; Protein Expression; Transcriptomics |
METABRIC; KM-Plotter |
2020 |
HER2-PI9 and HER2-I12: two novel and functionally active splice variants of the oncogene HER2 in breast cancer |
Tumour Biology; Tumour Progression & Metastasis |
Protein Expression; Transcriptomics |
- |
2021 |
Visual histological assessment of morphological features reflects the underlying molecular profile in invasive breast cancer: a morphomolecular study |
Tumour Biology |
Imaging; Transcriptomics |
TCGA |
2020 |
Volumetric high-resolution X-ray phase-contrast virtual histology of breast specimens with a compact laboratory system |
Methods & Techniques |
X-ray Imaging Modalities |
- |
2022 |
SLC1A5 co-expression with TALDO1 associates with endocrine therapy failure in estrogen receptor-positive breast cancer |
Drug Resistance; Tumour Biology |
Protein Expression; Transcriptomics |
GenExMiner; METABRIC; KM-Plotter |
2021 |
Prognostic significance of cathepsin V (CTSV/CTSL2) in breast ductal carcinoma in situ |
Tumour Progression & Metastasis; Outcome; Tumour Microenvironment |
Protein Expression |
- |
2019 |
The genetic architecture of breast papillary lesions as a predictor of progression to carcinoma |
Early Detection; Tumour Biology |
Genomics; Protein Expression; Imaging; Tissue Micro-Dissection |
METABRIC; TCGA |
2020 |
Derivation of a nuclear heterogeneity image index to grade DCIS |
Heterogeneity; Methods & Techniques |
Imaging |
- |
2020 |
PIK3Cδ expression by fibroblasts promotes triple-negative breast cancer progression |
Outcome; Tumour Microenvironment; Tumour Progression & Metastasis |
Mouse Model; Protein Expression; Transcriptomics |
TCGA |
2020 |
Discussion with French Biotech companies about potential collaborations |
Overview |
Review; Bioinformatics |
- |
2023 |
Predicting breast cancer recurrence using Natural Language Processing on imaging reports |
Early Detection; AI |
Clinicopathologic; AI |
- |
2023 |
Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers |
Outcome; Signalling Pathways; Drug Resistance |
Protein Expression; Transcriptomics |
Nottingham Series |
2020 |
Clinical utility of 'Shaken' biopsies for whole-genome sequencing |
BCNB Research Environment; BCNB Cohort Browser; BCNB Analytics |
Informatics; Bioinformatics; Clinicopathologic |
ICGC; TCGA; BCNB |
2025 |
The ITIM-containing receptor: Leukocyte-Associated Immunoglobulin-Like Receptor-1 (LAIR-1) modulates immune response and confers poor prognosis in invasive breast carcinoma |
Tumour Biology |
Protein Expression; Gene Expression |
cBioPortal; GenExMiner; TCGA |
2021 |
Exploring the potential of cycloidal computed tomography for advancing intraoperative specimen imaging |
Methods & Techniques |
Imaging |
- |
2021 |
XRCC1 deficient triple negative breast cancers are sensitive to ATR, ATM and Wee1 inhibitor either alone or in combination with olaparib |
Drug Resistance; Review |
Review |
- |
2020 |
The biological and clinical significance of glutaminase in luminal breast cancer |
Prognostic Assessments; Outcome |
Clinicopathologic; Genomics; Protein Expression; Transcriptomics |
GenExMiner; TCGA |
2021 |
A novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis |
Tumour Progression & Metastasis; Outcome |
Mouse Model; Protein Expression; Whole-Cell Patch Clamp Recording; Transcriptomics |
TCGA |
2023 |
A human breast cell atlas mapping the homeostatic cellular shifts in the adult breast |
- |
- |
- |
- |
ADAMTS3 restricts cancer invasion in models of early breast cancer progression through enhanced fibronectin degradation |
Tumour Microenvironment; Tumour Progression & Metastasis |
Protein Expression; Cell Culture; Image Analysis |
- |
2023 |
Evaluation of European-based polygenic risk score for breast cancer in Ashkenazi Jewish women in Israel |
Diversity & Equality; Methods & Techniques; Predictive Models |
Genomics |
Breast Cancer Association Consortium (BCAC) |
2023 |
Virtual alignment of pathology image series for multi-gigapixel whole slide images |
Methods & Techniques; Computational Workflow |
Bioinformatics; Imaging |
- |
2023 |
Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival |
Outcome |
Genomics |
- |
2023 |
Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research |
Review; Guidelines |
Review |
- |
2023 |
Multiscale deep learning framework captures systemic immune features in lymph nodes predictive of triple negative breast cancer outcome in large-scale studies |
AI; Outcome |
AI; Bioinformatics; Imaging |
- |
2023 |
High Inner Centromere Protein Expression Correlates with Aggressive Features and Predicts Poor Prognosis in Patients with Invasive Breast Cancer |
Prognostic Assessments; Outcome |
Clinicopathologic; Transcriptomics |
METABRIC; TCGA |
2023 |
A gap analysis of UK biobank publications reveals SNPs associated with intrinsic subtypes of breast cancer |
Review |
Review |
- |
2024 |
Breast Cancer Now biobank (BCNB) research platform |
Overview; BCNB Research Environment; BCNB Cohort Browser; BCNB Analytics |
Clinicopathologic; Bioinformatics |
ICGC; TCGA; BCNB; CCLE |
2025 |
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry |
Diversity & Equality; Tumour Progression & Metastasis |
Genomics |
Breast Cancer Association Consortium (BCAC) |
2023 |
Associations of a breast cancer polygenic risk score with tumor characteristics and survival |
Diversity & Equality; Outcome |
Clinicopathologic |
MINDACT Trial; Breast Cancer Association Consortium (BCAC) |
2023 |
A proteolytic landscape: understanding the role of myoepithelial cells in early-stage breast cancer progression |
Methods & Techniques; Tumour Progression & Metastasis |
3D Model |
- |
2023 |
Utility of stromal lymphocytes in diagnosis and predicting upgrade of B3 breast lesions from core biopsies |
Tumour Microenvironment; Predictive Models |
Protein Expression; Imaging |
- |
2022 |
Dynamic cancer biobanking for precision medicine |
Overview |
Epigenetics |
TCGA |
2025 |
A biobank perspective on use of tissue samples donated by trial participants |
Guidelines; Review |
Review; Guidelines |
- |
2022 |
Obituary - Margaret Wilcox |
Obituary |
- |
- |
2022 |
Capture Hi-C to identify regulatory variants and target genes influencing breast cancer risk |
Tumour Microenvironment |
Genomics |
TCGA; Breast Cancer Association Consortium (BCAC) |
2022 |
Radiotherapy biobanking: current landscape, opportunities, challenges, and future aspirations |
Review; Guidelines |
Review; Guidelines |
- |
2021 |
Exploring the potential of cycloidal computed tomography for advancing intraoperative specimen imaging |
Methods & Techniques |
Imaging |
- |
2021 |
Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment |
Outcome |
Clinicopathologic; Genomics |
Breast Cancer Association Consortium (BCAC) |
2021 |
Gene-environment interactions relevant to estrogen and risk of breast cancer: Can gene-environment interactions be detected only among candidate snps from genome-wide association studies? |
Gene Environment Interactions |
Clinicopathologic; Genomics |
Seoul Breast Cancer Study (SEBCS); Breast Cancer Association Consortium (BCAC) |
2021 |
Breast cancer risk factors and survival by tumor subtype: Pooled analyses from the Breast Cancer Association Consortium |
Lifestyle |
Clinicopathologic |
Breast Cancer Association Consortium (BCAC) |
2021 |
Combined associations of a polygenic risk score and classical risk factors with breast cancer risk. JNCI: Journal of the National Cancer Institute |
Early Diagnosis; Predictive Models; Risk Assessments |
Questionnaires; Genomics |
Breast Cancer Association Consortium (BCAC) |
2021 |
CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers |
Predictive Models; Risk Assessments |
Genomics; Questionnaires |
Breast Cancer Association Consortium (BCAC) |
2021 |
The clinical significance of oestrogen receptor expression in breast ductal carcinoma in situ |
Prognostic Assessments; Outcome |
Clinicopathologic |
- |
2020 |
A Mendelian randomization analysis of circulating lipid traits and breast cancer risk |
Tumour Biology; Risk Assessments |
Genomics |
Breast Cancer Association Consortium (BCAC) |
2020 |
Cancer burden is controlled by mural cell-β3-integrin regulated crosstalk with tumor cells |
Tumour Biology |
Mouse Model; Protein Expression; Imaging |
- |
2020 |
The prognostic significance of immune microenvironment in breast ductal carcinoma in situ |
Prognostic Assessments; Outcome |
Genomics; Protein Expression |
- |
2020 |
Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium |
Tumour Biology |
Genomics |
Breast Cancer Association Consortium (BCAC) |
2020 |
Extracellular matrix anisotropy is determined by TFAP2C-dependent regulation of cell collisions |
Tumour Microenvironment; Tumour Biology |
Mouse Model; Protein Expression; Microscopy; Transcriptomics |
- |
2020 |
CDC20 expression in oestrogen receptor positive breast cancer predicts poor prognosis and lack of response to endocrine therapy |
Drug Resistance; Tumour Progression & Metastasis; Prognostic Assessments; Biomarkers |
Clinicopathologic; Protein Expression; Gene Expression |
METABRIC; KM-Plotter |
2019 |
Clinicopathological characteristics of Basal-like Breast Cancer (BLBC): a comparative study between Egyptian and British patients |
Diversity & Equality; Tumour Progression & Metastasis |
Clinicopathologic; Protein Expression |
- |
2019 |
Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer |
Prognostic Assessments; Outcome |
Clinicopathologic; Protein Expression |
GenExMiner; TCGA; KM-Plotter |
2019 |
Geometric characteristics of collagen have independent prognostic significance in breast ductal carcinoma in situ: an image analysis study |
Tumour Biology; Outcome |
Protein Expression; Image Analysis |
- |
2019 |
Heparanase-dependent remodeling of initial lymphatic glycocalyx regulates tissue-fluid drainage during acute inflammation in vivo |
Tumour Biology |
Microscopy |
- |
2019 |
ERCC1 Is a predictor of anthracycline resistance and taxane sensitivity in early stage or locally advanced breast cancers |
Outcome; Drug Response |
Genomics; Proteomics; Transcriptomics |
METABRIC |
2019 |
SMAC, a computational system to link literature, biomedical and expression data |
Computational Workflow |
Bioinformatics |
BCNB; Gene Expression Omnibus |
2019 |
The molecular mechanisms underlying reduced E-cadherin expression in invasive ductal carcinoma of the breast: high throughput analysis of large cohorts |
Tumour Progression & Metastasis |
Genomics; Protein Expression; Transcriptomics |
- |
2019 |
Atypical ductal hyperplasia is a multipotent precursor of breast carcinoma |
Tumour Models; Tumour Progression & Metastasis |
Genomics |
- |
2019 |
Utility of ankyrin 3 as a prognostic marker in androgen-receptor-positive breast cancer. |
Tumour Biology; Signalling Pathways; Outcome |
Clinicopathologic; Genomics; Protein Expression; Transcriptomics |
METABRIC; TCGA |
2019 |
Prognostic role of androgen receptor in triple negative breast cancer: a multi-institutional study |
Prognostic Assessments |
Protein Expression |
- |
2019 |
A key genomic subtype associated with lymphovascular invasion in invasive breast cancer |
Tumour Progression & Metastasis; Outcome |
Imaging; Transcriptomics |
METABRIC; TCGA |
2019 |
The prognostic significance of lysosomal protective protein (cathepsin A) in breast ductal carcinoma in situ |
Outcome |
Protein Expression |
- |
2019 |
Oncogenic EP300 can be targeted with inhibitors of aldo-keto reductases |
Cell Models; Tumour Biology; Tumour Progression & Metastasis; Drug Resistance |
Protein Expression; Transcriptomics |
- |
2019 |
The clinical and biological significance of HER2 over-expression in breast ductal carcinoma in situ: a large study from a single institution |
Prognostic Assessments; Outcome |
Genomics; Protein Expression |
- |
2019 |
Legumain is an independent predictor for invasive recurrence in breast ductal carcinoma in situ |
Outcome |
Protein Expression |
- |
2019 |
Clinicopathological significance of ataxia telangiectasia-mutated (ATM) kinase and ataxia telangiectasia-mutated and Rad3-related (ATR) kinase in MYC overexpressed breast cancers |
Tumour Progression & Metastasis; Outcome |
Clinicopathologic; Protein Expression; Gene Expression |
Nottingham Series; METABRIC |
2019 |
The combined expression of solute carriers is associated with a poor prognosis in highly proliferative ER+ breast cancer |
Molecular Subtypes; Outcome |
Clinicopathologic; Protein Expression |
- |
2019 |
Overexpression of the cancer stem cell marker CD133 confers a poor prognosis in invasive breast cancer |
Outcome; Tumour Progression & Metastasis; Biomarkers |
Protein Expression |
METABRIC |
2019 |
SHON expression predicts response and relapse risk of breast cancer patients after anthracycline-based combination chemotherapy or tamoxifen treatment |
Outcome; Drug Response |
Protein Expression |
Nottingham Series |
2019 |
Expression of Lamin A/C in early-stage breast cancer and its prognostic value |
Prognostic Assessments; Outcome; Tumour Biology |
Protein Expression |
Nottingham Series |
2019 |
Genome-wide association study of germline variants and breast cancer-specific mortality |
Prognostic Assessments; Outcome |
Genomics |
- |
2019 |
Connexin 43 is an independent predictor of patient outcome in breast cancer patients |
Outcome |
Clinicopathologic; Protein Expression |
- |
2019 |
Glutamate dehydrogenase (GLUD1) expression in breast cancer |
Molecular Subtypes; Outcome |
Clinicopathologic; Genomics; Protein Expression; Transcriptomics |
METABRIC |
2019 |
The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor |
Outcome; Tumour Progression & Metastasis |
Mouse Model; Protein Expression; Genomics; Transcriptomics |
TCGA; KM-Plotter |
2019 |
Kinesin family member-18A (KIF18A) is a predictive biomarker of poor benefit from endocrine therapy in early ER+ breast cancer |
Prognostic Assessments; Outcome |
Clinicopathologic; Genomics; Protein Expression; Transcriptomics |
METABRIC; KM-Plotter |
2019 |
Investigation of hormone signalling and breast epithelial hierarchy in women at a high risk of cancer |
Tumour Biology; Risk Assessments |
Protein Expression; Transcriptomics |
- |
2019 |
Validation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissues |
Methods & Techniques |
Protein Expression; Cell Culture |
- |
2023 |
Prediction models for hormone receptor status in female breast cancer do not extend to males: further evidence of sex-based disparity in breast cancer |
Diversity & Equality; Tumour Biology |
Bioinformatics; Imaging |
TCGA |
2023 |
Implementing Fully Humanised Methods to Examine How the Endocrine Disrupting Chemical Bisphenol A Contributes to Breast Cancer Development |
- |
Cell Culture; Transcriptomics |
- |
2023 |
Characterisation of HER2 binding Affimer drug conjugates in 2D and 3D cell culture |
Tumour Biology |
Cell Culture |
- |
2020 |
Novel imaging modalities for the detection and characterisation of breast cancer |
Methods & Techniques |
- |
- |
2023 |
Collagen (XI) alpha-1 chain is an independent prognostic factor in breast ductal carcinoma in situ |
Tumour Microenvironment; Outcome; Biomarkers |
Clinicopathologic; Protein Expression |
- |
2019 |
Prolyl-4-hydroxylase Α subunit 2 (P4HA2) expression is a predictor of poor outcome in breast ductal carcinoma in situ (DCIS) |
Tumour Progression & Metastasis; Tumour Microenvironment; Outcome |
Protein Expression |
- |
2018 |
The significance of tumour microarchitectural features in breast cancer prognosis: a digital image analysis |
Tumour Progression & Metastasis |
Clinicopathologic; Imaging |
- |
2018 |
Thioredoxin-interacting protein is an independent risk stratifier for breast ductal carcinoma in situ |
Tumour Progression & Metastasis; Outcome |
Clinicopathologic; Protein Expression |
METABRIC |
2018 |
Dual mechanisms of LYN kinase dysregulation drive aggressive behavior in breast cancer cells |
Tumour Progression & Metastasis; Outcome |
Protein Expression; Transcriptomics |
- |
2018 |
Impact of breast cancer grade discordance on prediction of outcome |
Prognostic Assessments; Outcome |
Clinicopathologic; Imaging |
- |
2018 |
Heterogeneity of tumour‐infiltrating lymphocytes in breast cancer and its prognostic significance |
Prognostic Assessments; Outcome; Heterogeneity |
Protein Expression; Imaging |
- |
2018 |
Saccharomyces cerevisiae-like 1 (SEC14L1) is a prognostic factor in breast cancer associated with lymphovascular invasion |
Tumour Progression & Metastasis; Tumour Biology; Outcome |
Genomics; Protein Expression; Imaging; Transcriptomics |
GenExMiner; METABRIC |
2018 |
Clinicopathological and prognostic significance of Ras association and pleckstrin homology domains 1 (RAPH1) in breast cancer |
Tumour Progression & Metastasis; Outcome |
Genomics; Protein Expression; Transcriptomics |
METABRIC; TCGA |
2018 |
Stanniocalcin 2 expression is associated with a favourable outcome in male breast cancer |
Diversity & Equality; Tumour Progression & Metastasis; Outcome |
Protein Expression; Transcriptomics |
Oncomine |
2018 |
Co-expression of nuclear P38 and hormone receptors is prognostic of good long-term clinical outcome in primary breast cancer and is linked to upregulation of DNA repair |
Prognostic Assessments; Outcome |
Protein Expression |
METABRIC |
2018 |
An engineered human adipose/collagen model for in vitro breast cancer cell migration studies |
Tumour Biology; Tumour Models |
Cell Culture; Fluorescence Microscopy |
- |
2018 |
Clinical and biological roles of Kelch-like family member 7 in breast cancer: a marker of poor prognosis |
Tumour Biology; Outcome |
Clinicopathologic; Genomics; Protein Expression; Transcriptomics |
GenExMiner; METABRIC |
2018 |
BQ323636.1, a novel splice variant to NCOR 2, as a predictor for tamoxifen-resistant breast cancer |
Drug Resistance; Biomarkers; Outcome |
Mouse Model; Protein Expression; Transcriptomics |
- |
2018 |
Prognostic significance of tumor-infiltrating lymphocytes in ductal carcinoma in situ of the breast. |
Prognostic Assessments; Outcome |
Imaging |
- |
2018 |
Breast cancer histologic grading using digital microscopy: concordance and outcome association |
Methods & Techniques; Prognostic Assessments |
Imaging; Microscopy |
- |
2018 |
Immune infiltration in invasive lobular breast cancer |
Outcome; Tumour Biology |
Protein Expression |
Nottingham Series; BIG 02-98; METABRIC; TCGA |
2018 |
Characterising the adipose-inflammatory microenvironment in male breast cancer |
Diversity & Equality; Tumour Biology; Outcome; Tumour Microenvironment |
Protein Expression; Histological examination |
- |
2018 |
The multifunctional solute carrier 3A2 (SLC3A2) confers a poor prognosis in the highly proliferative breast cancer subtypes |
Prognostic Assessments; Outcome; Molecular Subtypes |
Clinicopathologic; Genomics; Protein Expression; Transcriptomics |
METABRIC |
2018 |
Mediator complex (MED) 7: a biomarker associated with good prognosis in invasive breast cancer, especially ER+ luminal subtypes |
Outcome |
Clinicopathologic; Protein Expression; Transcriptomics |
Nottingham Series; GenExMiner; METABRIC |
2018 |
Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers |
Tumour Microenvironment; Outcome |
Protein Expression; Proteomics; Imaging; Transcriptomics |
- |
2018 |
The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours |
Prognostic Assessments; Outcome |
Clinicopathologic; Genomics; Protein Expression; Transcriptomics |
METABRIC |
2018 |
MYC regulation of glutamine-proline regulatory axis is key in luminal B breast cancer |
Tumour Progression & Metastasis; Outcome; Tumour Biology |
Genomics; Protein Expression; Transcriptomics |
METABRIC |
2018 |
Analysis of clonal expansions through the normal and premalignant human breast epithelium reveals the presence of luminal stem cells |
Cancer Stem Cells; Clonal Dynamics |
Protein Expression; Tissue Micro-Dissection |
- |
2018 |
Evaluation of CDK12 Protein Expression as a Potential Novel Biomarker for DNA Damage Response-Targeted Therapies in Breast Cancer |
Outcome |
Clinicopathologic; Genomics; Protein Expression; Transcriptomics |
Nottingham Series; METABRIC; TCGA |
2018 |
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors |
Early Detection |
Epigenetics; Transcriptomics |
- |
2017 |
CIP2A expression predicts recurrences of tamoxifen-treated breast cancer |
Drug Resistance |
Protein Expression |
- |
2017 |
POPDC1 is suppressed in human breast cancer tissues and is negatively regulated by EGFR in breast cancer cell lines |
Biomarkers |
Protein Expression |
- |
2017 |
Rho-GTPase activating-protein 18: a biomarker associated with good prognosis in invasive breast cancer |
Prognostic Assessments; Outcome; Tumour Progression & Metastasis |
Clinicopathologic; Protein Expression; Transcriptomics |
GenExMiner; METABRIC |
2017 |
Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer |
Drug Resistance; Cancer Stem Cells; Tumour Progression & Metastasis |
Protein Expression; Transcriptomics |
- |
2017 |
Ki67 expression in invasive breast cancer: the use of tissue microarrays compared with whole tissue section |
Methods & Techniques |
Clinicopathologic; Protein Expression |
- |
2017 |
How is Herstatin, a tumor suppressor splice variant of the oncogene HER2, regulated? |
Tumour Biology |
Proteomics; Transcriptomics |
- |
2017 |
A case-matched gender comparison transcriptomic screen identifies eIF4E and eIF5 as potential prognostic markers in male breast cancer |
Diversity & Equality; Signalling Pathways; Biomarkers; Tumour Biology |
Protein Expression; Transcriptomics |
- |
2017 |
Clinical impact of tumor DNA repair expression and T-cell infiltration in breast cancers |
Tumour Biology |
Protein Expression |
- |
2017 |
Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function |
Tumour Progression & Metastasis; Tumour Microenvironment |
Protein Expression; Cell Culture; Transcriptomics |
- |
2017 |
Expression of CDK7, Cyclin H, and MAT1 is elevated in breast cancer and is prognostic in estrogen receptor-positive breast cancer |
Outcome |
Protein Expression; Transcriptomics |
METABRIC; Oncomine |
2016 |
Management of breast cancer in an Asian man with post-traumatic stress disorder: a case report |
Diversity & Equality; Case Study |
Review |
- |
2016 |
An evaluation of matrix-containing and humanised matrix-free 3-dimensional cell culture systems for studying breast cancer |
Methods & Techniques |
Cell Culture |
- |
2016 |
The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis |
Tumour Progression & Metastasis |
Mouse Model; Transcriptomics |
- |
2016 |
3-D tissue modelling and virtual pathology as new approaches to study ductal carcinoma in situ |
Tumour Progression & Metastasis |
Review; Protein Expression; Imaging |
- |
2015 |
Nav1.5 regulates breast tumor growth and metastatic dissemination in vivo |
Tumour Progression & Metastasis |
Mouse Model; Protein Expression; Whole-Cell Patch Clamp Recording; Transcriptomics |
- |
2015 |
Epigenetic mechanisms of breast cancer prevention by the Type II diabetes mellitus agent metformin |
Tumour Biology; Signalling Pathways; Risk Assessments |
Epigenetics; Protein Expression; Transcriptomics |
- |
2019 |
Epigenomic and genomic dissection of oestrogen receptor-positive breast cancer |
Tumour Biology; Heterogeneity; Drug Resistance |
Epigenetics; Genomics |
- |
2019 |
Electrophysiological characterisation of ion channel activity in tumour slices |
Tumour Progression & Metastasis; Outcome |
Mouse Model; Protein Expression; Whole-Cell Patch Clamp Recording; Transcriptomics |
- |
2018 |
Exploring the roles of the Protein Kinase N family in breast cancer |
Tumour Microenvironment; Tumour Progression & Metastasis |
Mouse Model; Protein Expression |
- |
2018 |
Mechanostimulation of integrin αvβ6 and fibronectin in DCISmyoepithelial cells |
Tumour Microenvironment; Tumour Biology; Tumour Progression & Metastasis |
Protein Expression; Transcriptomics |
- |
2018 |
The role of microRNAs in the fibroblasts of triple negative and basal-like breast cancer |
Tumour Biology |
Protein Expression; Transcriptomics; Review; Drug Resistance Assay; Imaging |
- |
2017 |
Epigenomic profiling of oestrogen receptor-positive breast cancer |
Drug Resistance; Heterogeneity; Tumour Progression & Metastasis |
Epigenetics |
- |
2017 |
A comparative study of male versus female breast cancer identifies overexpression of eiF signalling pathways in male breast cancer providing opportunities for a therapeutic window |
Diversity & Equality; Tumour Biology |
Protein Expression; Transcriptomics |
- |
2016 |
Breast Cancer Now Cell Culture Programme: a bespoke resource for the research community |
Overview |
Bioinformatics; Cell Culture Programme |
- |
2016 |
A 3D in vitro model of the human breast duct: unravelling myoepithelial-luminal interactions in breast cancer |
Tumour Biology; Methods & Techniques |
Cell Culture |
- |
2016 |
Multi-modal AI for comprehensive breast cancer prognostication |
Tumour Progression & Metastasis; Outcome; Predictive Models |
AI; Imaging; Clinicopathologic |
- |
2024 |
A novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis |
Tumour Progression & Metastasis; Outcome |
Mouse Model; Protein Expression; Whole-Cell Patch Clamp Recording; Transcriptomics |
- |
2024 |
A single-cell atlas enables mapping of homeostatic cellular shifts in the adult human breast |
Cell Atlas; Early Detection |
Clinicopathologic; Protein Expression; Transcriptomics |
- |
2024 |
validation of DCIS markers to predict IDC |
Methods & Techniques |
Genomics |
- |
2025 |
Epigenetic deprogramming by disruption of CIZ1-RNA nuclear assemblies in early-stage breast cancers |
Diversity & Equality; Informatics Research Environment |
Clinicopathologic; Genomics |
Genes & Health; TCGA; BCNB; Genomics England |
2025 |
The Lancet Breast Cancer Commission |
Review |
Review |
- |
2024 |
The clinical and molecular landscape of breast cancer in women of African and South Asian ancestry |
Methods & Techniques; Tumour Microenvironment |
Protein Expression; Cell Culture |
- |
2025 |
ECM degrading bacteria boost CAR T cell therapy in solid cancers |
Methods & Techniques |
Spectroscopy |
- |
2025 |
Vitacrystallography: Structural Biomarkers of Breast Cancer Obtained by X-ray Scattering |
Methods & Techniques |
X-ray Imaging Modalities |
- |
2024 |
Subtype-Specific Detection in Stage Ia Breast Cancer: Integrating Raman Spectroscopy, Machine Learning, and Liquid Biopsy for Personalised Diagnostics |
Methods & Techniques; Molecular Subtypes |
Transcriptomics; Protein Expression; Imaging; Tissue Micro-Dissection |
- |
2025 |
Persistence of BRCA1and RAD51C methylation after neoadjuvant chemotherapy in high risk TNBC |
Outcome |
Epigenetics |
- |
2024 |
katana |
- |
- |
- |
- |
The amino acid transporter SLC7A11 expression in breast cancer |
Tumour Biology; Outcome |
Epigenetics; Genomics; Protein Expression; Transcriptomics |
GenExMiner; METABRIC; TCGA |
2024 |
Stromal lymphocytes are associated with upgrade of B3 breast lesions |
Tumour Microenvironment; Predictive Models |
Clinicopathologic |
- |
2024 |
The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis |
Tumour Progression & Metastasis |
Mouse Model; Protein Expression; Image Analysis |
- |
2014 |
Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer |
Tumour Evolution; Heterogeneity |
Epigenetics; Genomics |
METABRIC; TCGA |
2018 |
Immunopeptidomic profiling of HLA-A2-positive triple negative breast cancer identifies potential immunotherapy target antigens |
Prognostic Assessments |
Protein Expression |
- |
2018 |
Glucocorticoid receptor expression predicts good Outcome in response to taxane-free, anthracycline-based therapy in triple negative breast cancer |
Biomarkers; Tumour Biology |
Protein Expression; Transcriptomics |
- |
2020 |
Subcellular mRNA localization regulates ribosome biogenesis in migrating cells |
Tumour Biology; Tumour Progression & Metastasis; Review |
Review |
- |
2020 |
Tumour promoting HER2 splice variant Δ16HER2: Regulation and implication in breast cancer |
Drug Resistance |
Protein Expression; Transcriptomics |
- |
2017 |
Reciprocal Interactions Between the Gut Microbiome and Mammary Tissue Mast Cells Promote Metastatic Dissemination of HR+ Breast Tumors |
Tumour Biology |
Fecal Microbiota Transplantation; Mouse Model; Transcriptomics |
- |
2022 |
Defining the role of MYBL2 in breast cancer progression |
Review |
Review |
- |
2020 |
Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues |
Methods & Techniques |
Epigenetics; Transcriptomics |
TCGA |
2015 |